the haps impact march 2019

STAY CONNECTED...

MARCH 2019INSIDE THIS ISSUE:

022019 Marathon Wrap Up

032019 Marathon Donors Continued

05 Article: Prodromal Parkinson's

06Exercise and Support Group Schedule

09 HAPS Parkinson's Awareness Month EventNew Online Videos Richmond Brain and Body Class

10Article: Coffee and Parkinson's Protection in the Making

11Contributions and TributesApril 6th PD 101 Class for Newly Diagnosed

Impact has different definitions to different people and in different contexts. Impact may be thought of as force, influence, meaning, or significance. It can be conceptualized as the long-term effect of an outcome or something we hope to achieve. Whether it is programmatic planning or overarching organizational theory, HAPS considers impact in all the things we do. We use impact as our compass as we develop and implement programs and services; it is how we evaluate our work and where we find our inspiration. To HAPS, impact also means innovative, transformative, and catalytic, as well as, empowering, sustaining and supportive.

In 2018, HAPS proudly provided 59,638 total hours of service to those with Parkinson's disease and their family members. HAPS furnished free transportation to 110 riders who took a total of 1,405 trips to and from doctor appointments and HAPS groups. Fifteen eligible clients received a total of $5,000 in emergency funds to assist with medications, medical equipment or groceries. In addition to nearly 100 home visits completed by social workers, our 2018 Annual Summer Lecture Series, PD 101 program for those who have been recently diagnosed, and Caregiver Conference provided 490 individuals with 3,396 hours of education.

Through various evaluations, you reported that after participating in or receiving these services, you felt more connected to others, better educated and prepared for the future, less isolated, and more confident in your ability to manage your disease. Impact goes far beyond outcomes. It is the real-life difference something or someone makes. HAPS is reminded every day of the impact our clients have on the trajectory, depth, quality and richness of what we do. Each person who shows up and shares a part of who they are gives our programs meaning and perhaps, without knowing it, contributes greatly to their success.

Donors too, have impact when they contribute to the organization creating the opportunity to connect more people to greater resources. As we endeavor to grow, expand and meet the ever increasing needs of our community we are asking for your assistance. The story we tell funders isn't about HAPS, it is about you. We work to promote understanding of the disease and how it affects the lives of those who are living with it, but we also strive to provide a bigger picture of what life with Parkinson's can be.

As we work to create the narrative of HAPS, we recognize that it is your voice that can best tell our collective story. We want to hear from you–we would like to formally capture what so many of you have shared with us in passing. Let us know how what impact HAPS has made on your life. You can send your story, of any length, by email to [email protected] or regular mail to the HAPS office. Help us tell our story by sharing yours.

THE HAPS IMPACT

HOUSTON AREA PARKINSON SOCIETY2

STRONG FINISH FOR TEAM HAPS!

Margaret AbbottJohn AdamsFranklin AdamskyMartha AguilarCarol AhlesJoe AhmadLeticia AldanaM. Jane AlexanderEdward AlmarazMaria AlvaChristy AmunyKay AndrewsMichael AquinoPatty AquintoAngelina AquintoApril, Scott, Wyatt, Wade, and Walker AquintoAngel Archer-MoralesPaula ArnoldHarvey AronsonDorothy and Lynn AshbyManal AssalLinda AstalaSteve AtchisonDeborah A. AtchisonNancy AtchisonBarbara AtchisonDavid AtwoodAmy AugustineAmanda AustinArturo AvilesDonna AvolioDavid BabinPatricia BahrTeresa BaileySteve BairJanet BakerJudy and Bobby BakerKen BallardWally BarberBarbeque ExchangeBill BarneyLinda BarryMike BassettAnnette BaumgartnerAlan BazardRoslyn BeamWanda BeardRussell C. Beard, P.C.Scott Beaty

Stephen BeaudryAshley BeavanCharline BeebeJacob BekkenMelanie Bell MainwaringJeremy BelliniJennifer BennettElizabeth BentleyJulie BergeronBarbara BergersenPatrick BerkebileJan BettisBrandy BeverlyGauri BhattacharyaTari BirkeloSara BishopJ. Robert BlackJorge BlancoSaba BlandingBen BlankenshipAmy BoatmanVeronica BobadillaRobert BogerMichael BonnotMarie BottTanya BoucherClayton BoutainWill BowenJanet and Todd BowerMelinda BowmanArlene and Dale BoyerAnnie BradburyAlice BradleyG. Todd Brady, DMDNita BrantleyLucy BrantsKathy and Will BrayNicole BrennigChip BrennigGary BrentlingerChris BrewsterJohn BridgerMichael BridwellBette and Ron BriegerBeverly and Bob BrittonDebra BrodPaul BrooksBarbara and Curt BroussardDerek BrownMichael Brown

Jerry BrownMishael BrownDon BrownVirginia BrownJunie Ledbetter BroylesBart BrozMary Ellen BryantDonald BuckholtPat BuckleyTheresa BuenoVilma BurgettTambra BurnsAnita and Jim BurrPat BurtonSusan and Brian BuschJeanne ButlerKelly and Billy BuzzettJoe BuzzettDiane ByersBlake and Cory ByersIsabelle CabreraIsabella and Nicanor CabreraJuan CalderaSam CaldwellFrank CaloAlice CalvinAndrea CamachoRachel CameronPatti CameronMichael Campbell Debbie and Scott CampbellAnne CampbellKim CampbellDale CannonJoan CantrellDiana CantuLucia CantuAdrian CantuMarissa CantuElizabeth CareyPatti and Kirk CarlosJessica CarlsonPatricia CarlsonRebecca CarlsonKaren CarmanJanet CarpenterCarol CarrKathleen CarricoJoe CarrizalesKeith Cartwright

William CarySuggie CaseyCheryl CaseyMichael CaseyConstance CaseyMary Kay CaseyPatrice CassidyJoe CastilloNancy and David CastroSidney CauthornKeri CauthornRuthann and Bill CazalasRebecca CemoTomas CernikovskyBarbara ChandlerVirginia Watt ChandlerStephanie ChapmanMary Jo ChapmanNina and Frank ChapmanWendy ChauvinRebecca ChavezRobert ChickGary ChilesJennifer CianciulliStephanie ClarkVivian ClineDavid CloudAnne CocoPaul CohenCledwyn ColeHugh ColeBlake CollierBrenda CollinsSusie and Fred CollinsJack CollinsSandra ConnatserJen and Chris ConnerLinda and Samuel ConnerLaura ConnerClare CooperNina CooperSamantha CooperMark CopelandGayla Corley PruettKatharine CornwellCaryl CoronisYvonne CosgroveMichael CosgroveJoe CostantinoNicolas Costanzo

Carlo CotroneChristian CourtneyJanet CoutureSue CoxTravis CrabtreeJo CrakeMarjorie CrawfordLouise CriderKathleen CristTara CrittendenLarry CrutcherMelissa DaileyBrian DalmCharlene DaltonMichelle DalyMarcy DandyJanelle and Lawry DanielDavid DavenportDarlene DavenportJanis Davis-StreetEsmeralda De La CruzAlicia M. DeasisKatelijne DecraeneMonique DelatorreKatie DeLeonNathan DennisClayton DevinFilomena DiazKelly and Mark DickinsonMichael DickmanJean Paul DimaalaGilda DimayugaShannon DobynsMike DodsonAshley DominguezKacy DominguezCynthia DonaldsonThomas DonekerAndrea DonleyAlice DorseyKaren and Brad DouglasJoyce and Tom DowneyGiselle DoyleRichard DoyleLarry DunnAshley and Long DuongErin DutkaKelly DyerGreg DykemanE.R. Norwood Expense Account

The final finish-line has been crossed as fundraising for the 2019 Chevron Houston Marathon wrapped up in February. The collective efforts of 2019 TEAM HAPS raised an astounding $125,860 and increased Parkinson’s awareness with a massive group of nearly 200 runners and walkers participating in race weekend. We thank our dedicated Marathon Chairs, Jeff Hurlbert and Sherry Hunter, as well as all the walkers, runners, fundraisers, volunteers, spectators, and the more than 800 donors below who participated in making this the most successful Marathon event in HAPS' 25 years of participation!

TOP 10 FUNDRAISERS1. Mike Hendryx–$8,8502. Sherry Hunter–$4,0303. Fred Stephens–$3,7504. Jeff Hurlbert–$3,400

5. Kathleen Crist–$3,2106. Kathy Smith–$2,7507. Robby Payne–$2,3008. Suggie Casey–$2,150

9. Ashley Hurlbert–$2,02610. Leon Keeble–$2,000

3MARCH 2019 HAPS HAPPENINGS

Gary EbdonDebbie EdwardsZach EfirdEllen EfsicBonnie EgbertPenny EgenesAbby EisoldMichelle EllisPhil EltingSlater ElzaNoble EnergyNancy EnnisEnterprise HoldingsCarey ErdmanChris ErmlichCandace EscobarJeanne and John EslerCarla EspinozaGloria EsquedaMonica EsquedaJose EsquedaDolores EsquedaJennifer EsquiveWarren EvansMichael EvertExxonMobil FoundationDave FaberRegina FabianBeth FainAlbert FayJohn FeatherAimee FelioSheilah and Kevin FichtnerHolly FitzGeraldMelanie FlavinAnn FleischmannSheree FlemingBrian FolloderJeff FolloderJody FolloderJoe FordPhilip FrancisPaul FrancisRene FrancoCurtis FrasierFreeport LNGSteve FrenchKimberly FrickDoug FryeDebra and Tristan FuentesDavid FusselmanCheryl GahmAdriano GalanoGreg GangluffConnie GangluffAbel GarciaLamoyne GarrisonJuan GarzaLeslie Garza ConstanfJames GascoyneLarissa GavinMarian GeerEllen and Jeffrey GehrsCharles GentlesJason GerencserChad GerkeKendall GibbsKerry GilbertStanley GillespieChristine GladbachChristina GleasonCourtney GoffSamantha GonzalezHarold Goodearle

Janet GoodfoxLenore and Marty GordonVicki GormanRhonda GraffDeborah GrausteinBorgia Graves IiiScott GreenPeggy GreenHilary GreeneAnn GreenePhilip GriffithPatricia GrossmanMichael GroverCristina GuerreroJames GuerreroMichael GuityIvete HablinskiLana HadlockBeth and Dale HahnLibby HahnShahmeer HalepotaMichelle HallgrenLee HamelJudith HamelersRachel HamelersJason HanlonDebra HarlowMurphey HarmonMelinda and Frank HarmonForrest Harrell Jr. Colleen and Robin HarrisHazel HarronDonna and Craig HartmanD. Willis HartmanDavid HartmanKeith HartmanLisa HathawayBen HearnJean and Donald HeinemanCliff HelmcampGail and Mike HendryxPatricia Ann HerreraHolly HerreraTodd HewgleySusan and David HillJanet and George HillKatie HinszDon HisleDiedra HlinskyMaria HoffmanGinger and Jim HollyCindy HolmesDebbie HorganHorne FamilyBonnie HortonReagan HoughElisabeth and Dennis HoughLani HouseSandra HowellSusan HrachMarilyn HrachMatthew HuffGlynis and Johnny HugghinsJune and Larry HuntChristine HunterSherry and Dean HunterJim HurHurlbert Family Foundation Ashley and Jeffrey HurlbertJim HurlbertKim and Tim HurlbertTerrance HurlburtKaty HussMichael Huss

Adam HussAlesia HustonChaille HutchesonJan HutchinsonDallas HutchinsonDavid HyattAnna HydeMontie HydenApril IbarraMarlon IgnacioJennifer IsamingerKathy IvesWilliam JacksonPreeti and Paresh JainNausheen JamalEmily JamesJerry JeanmardBetty JoeFred JohnsonKirkwood JohnstonSusette JonesChristine JonesKathleen JonesAnna KaganKeaton KainerPhyllis and Phil KalzDave KapavikJudy KatzBenjamin KatzSara KauffmanAnnette and Mike KeadyAnn KearyLeon KeebleStephanie and Jeff KeiserNatalee KelaherWendy KellyJohn KellyRobert KennedyDonna KennedySarah KerriganJenny KertsosSherry KingDon KingDavid KinnanSue Kirby-WebbJohn KirkseyIsabella KlebMishell KneelandKelly KnightCheryl KnottRich KoehlerCarol and John KollehnerKaren KoprivaAndi KreuerKeith KreuerCynthia KreuerKenneth KruseNancy KryderTrevor KulviFred KunzingerJohn Anthony KupersmithBrian KurrNigel LanderAmy LangfordAdrianne LashleyJudith LasseterKevin LaudadioTim LaudadioPaul LaudadioBrenda and Timothy LawtonAngie LaytonHarriet and U.W. LeavellDavid LedyardScott Lee

Doreen LeeKathleen LeFloreMolly LeinsdorfNatalie LekkasSara LemoineEric LeonardTim LeslieAugusta LevineMichelle LewisCraig LinJenny LinGreg LinneyShelley LinseyJanet and David LionbergerShirley LockeJon LuckettFrank LuethLaurei and Doug LynchOdette MaceBeatriz MaciasSteve MacomberPamela MadereAlonso MagoJoseph MaierNicola MaitlandJohnnie MalloySusan MarinoJames MarkgrafChristine MarkhamLarry MartinAnne MartinKathy MartinezLisa MashnoukGeorge MastersonStewart MastersonCinda and William MatthewsJames McCabeRobin McCallumHaley McCannAudrey and Mike McCarthyAnna and Mike McClaneAnna McClaneDinah McClymondsJane McCourtPatsy McDonaldLarry McGintyChris McinroyCaroline McKnightSylvia McLartyJim McLeodHeather McMillanMelinda McNamaraMatt McNeilBeverly and Doug MeadenSharon and Peter MeadenDavid MeadenCrystal MeadowsKarla MedinaDale and David MeffordMeredith Meissner-CroweSarah MerrillMiguel MeuszKate MeyerMissy MeyerMary MihalopoulosJoni MillerJulie MillerJasmine MillerPolly MillerJeffrey MillerJoyce MilnerPatricia MireAlexis MirelesKarin and Greg Monson

Charles MooneyMichael MoralesArdith MorganTina MorrisHolly MorrisPatricia MounceMarvin MuellerSue MuenksJohn MunseyAnn MurdockPamela MurrahDavid MusgroveNancy NabilsiJody NealyHouston NetherlandAaron NeusKristen and Rob NeviRobin NicholsNaomi NickensMarjorie NogueiraGerald NormanBeth and Dan NorthSharleen NoskeJoyce Nunez GaryLori OchoadaEdward O'DonnellCarolyn and Joe O'DonnellVincent OdorisioSarah OfnerMari OkabayashiLisa O'LearyMargaret OlszewskiJoann OlvedaMisty O'NealKaren OrtizJulie and Chip OudinPatti OwensRosa OzunaJackie PaceDebbie and Tom PacholderNicole PalmRebecca PalmerVirginia PapeErin ParchmanRamon ParedesCharlie ParkerRoma and Ray ParkerSarah and Chris ParksMary PasleyFernando PavonWilliam PayneJulie PayneShelby PayneRyan Shelby PayneHarvey PearlsteinJennifer Pearlstein FleckTish and David PedenLisa PepinSandra PerezConsuelo PerezHal PerkinsMadelyn PerryThomas PerryJanis PetnerElaine PhillipsDwayne and Melissa PickettBarb J. PiehEileen and Frank PiergiovanniErin PikoffCindy PilkentonJames S. PittmanShelly PittsBridget PoiznerAlan Poizner


Kari PokrzywaShanel PontigoKim PotterBetty Jo PowersPatrick PowersJoshua PrenticeThomas PressRenda Claudine PriestElizabeth PrinceKenneth PrindleMiriam PrioleauMonica QuinteroBonnie QuintonShannon QuisenberryJake RaineyBrad RankinBarbara and Wayne RansbottomEliza RappaportAmanda RedmonJay RedmonScott Pat ReedGeorge ReedKathleen ReedyMary Ellen and Robert ReidTracy RichardsonCarole RiekertCharlie RiggsJames M. Riley, Jr.Marina RiosCatherine RivasLauren RobertsonJane RobinsonCathie RobinsonKathy RobsonAngelica RodriguezAlyssa RodriguezCristobal RodriguezPatti RomanoAshley RosenbergMelissa RosenbergSheila RosenbergGary RossJanetta RossKaren and Gary RossAlan Rotkiewicz

James RubinCynthia RubioMaribel RuizDiana and James RutherfordJeremy SabioJanet SabioMary SabioJoshua SabioJoseph SabioRanya SalamaYessica SalazarFred SalazarTeresa and Charlie San MiguelMarylou SanchezErick SandlinRosanne SantacroceRavi SanthanamNeal SarkarMatt SavatskyJanis and Bruce SavatskyDenise SaylorLaura SchaferGloria ScheelConnie SchillerSarah SchlacksSusan SchmaelingCristy and Mike SchmidtJanet SchmidtAnn SchmidtWard SchultzJamie and David SchupePatti SchwartzBarbara SchwarzRussell ScottLaura ScyrkelsKaren SeefeldtManuel ServellonJanice ShaffnerBridgett SharpeJennifer ShenefeltScott SherkBonnie SherkAmber ShermanTifney ShroyerSally Shu

Patricia SilvaRobert SimeKaren and Greg SimpsonRob SimpsonBlake SimsPamela SkaufelAmy SmallKim SmilieRia SmitHolly SmithAlbert SmithRachael SmithDavid SmithMeryl SmithKatherine SmithDonna SmithSandra SmithAlison SmithMitchell SmithPatricia and Russell SmithSteven SonnierWilliam SpechtJoyce SpencerAnn SprovachCrews SprovachMary SpruntJarrod StaffordGretchen and Jim StallingsJudy and Sherrill StarrFrances SteeleCharlie StegemoellerDavid SteinKaren StellabotteFred StephensBob StephensonNancy SterlingGordon SterlingDoris and Robert StewartNicholas StillmanMartha and David StoneBrent StoolRoland StoteLori StoufferAnn and Tim StoutPaul StreetJudy Sullivan

Elizabeth SumanLisa and Ferdie TanjuatcoJudy TateRonald TaylorBill TaylorAmmetta TaylorMartin TaylorMarita TeeElizabeth TennantHoward TenneyThe Rodney H. and Judy E. Margolis FoundationEric ThiedeMaddy ThomasMichael ThompsonPaul ThompsonCheryl ThorneShirley ThorntonTim ThurmondRose TimmerCamden TissuePat TomainoJerry TownsleyThuy TranFreddie TsaoJackie and Jack TuckerJustine UlrichRita UpadhyayaLindsie UpsonChristina UribeMarcela UribeJoyce UribieVeronica ValdesWilliam VanceGeetha VargheseAmanda VasquezSandra VasquezDebra VaughnAmanda VelaTracey VelezAntonette VeraSandra VidalVanessa VillaAdriana VillaTamara VinsonRoland Volker

Mike VolpeBarb and Dave VolzJim VonderhaarRichard WahlsBobby WaldenSusan WaldronRita WalkerJane WallaceNikki WalleyKelly and Jeff WallisDerek WalshRick WannemacherShayna WattsAlix WaughAllyson WeathersLeslye WeaverElizabeth WeedmanRichard WeirichPeter WeldJacqueline WeldyKasey WendelSharla WendtMeredith Wesson DroletMurrell WhelanWesley WilliamsNancy and Gary WilliamsonSusan WillifordAlice WinklerJulia WintonHeather WoltzRanelle WoolrichGuy WorshamSandy and Lee WotizMax WrightAmanda WuenschePatrick YarboroughLynn YarwoodMichele YorkSteven ZakinGabriel ZamoraPamela ZamoraSusan Zarate

many thanks to our 2019 chevron houston marathon corporate donors


Parkinson’s disease was initially described in 1817 by a London physician, James Parkinson, who described some major motor features including tremor, rigidity and gait disturbance. It took another 50 years before neurologist Dr. Jean-Martin Charcot described bradykinesia, or slowness of movement, as a separate cardinal feature of the disease, providing us with a set of motor impairments on which we rely to make the diagnosis of Parkinson’s disease.

Studies have indicated that the neurodegenerative process of Parkinson’s disease begins decades before the motor signs actually appear. Usually dopamine is depleted by approximately 40% before the first clinical motor sign appears. Before these motor symptoms appear, there are non-motor symptoms, which if recognized early, allow for initiation of potential neuroprotective therapies. In fact, current medications are not effective for the non-motor symptoms nor do they slow down the progression of the disease. If we could stop the disease from progressing or even delay it by 5, 10 or 20 years, we could add to the quality of an individual's life.

Today, I would like to talk about the prodromal or early symptoms; the stage in which individuals do not fulfill diagnostic criteria for Parkinson’s disease, but do exhibit signs and symptoms that indicate a higher than average risk of developing motor symptoms and a diagnosis of Parkinson’s disease in the future. These symptoms are non-motor.

Hyposmia–Olfaction (sense of smell) is impaired in about 80-90% of patients at the time of their Parkinson’s disease diagnosis. Most people are unaware of their deficit. Loss of smell however is a very non-specific finding especially in individuals who have a history of smoking, allergies or nasal polyps. One study suggested that hyposmia after four years was not in fact associated with Parkinson’s disease risk.

Constipation–This is a common symptom noted in the prodromal phase affecting 28-61% of patients. One study suggested that individuals with fewer than one bowel movement per day had an approximately 2.7 times higher risk of developing Parkinson’s disease compared to individuals with more frequent bowel movements. Constipation can be noted almost 20 years before the diagnosis of Parkinson’s disease making it one of the earliest signs. However, just as with loss of smell, it is a very non-specific finding and can be caused by a variety of things especially in the elderly population–lack of activity, diet, medications, etc.

Mood disorders–Studies have suggested that both anxiety and depression tend to become more significant in patients

about 1-2 years before a Parkinson’s disease diagnosis. Thus, mood disorders tend to be a late marker of the prodromal phase. However, similar to the symptoms of constipation and hyposmia, mood disorders are also non-specific.

REM sleep behavior disorder–This is characterized by dream enacting behavior during REM sleep which can be described as talking, screaming, or movement of the upper extremities. Usually the patient is unaware of these activities and it is noted by their bed partner. Studies have suggested that between 50-70% of individuals with confirmed REM behavior disorder will progress to develop a neurodegenerative process such as Parkinson’s disease. Of all the different symptoms described thus far, REM sleep behavior disorder has the greatest association with the future development of Parkinson’s disease. Given the high risk of progression, an appropriate workup is highly recommended. It is also important to mention that although it can occur with certain medications, it occurs in approximately 5-8% of the general population over the age of 60.

As you can see the prodromal symptoms can be very non-specific and certainly can be caused by a variety of different pathologies. In my practice, every month I see a handful of patients who have family members with Parkinson’s disease and have read about these prodromal symptoms and would like to be evaluated. If their clinical examination is normal, the diagnosis of Parkinson’s disease cannot be made. Also, at this time there are no reliable tests to indicate with certainty who will develop Parkinson’s disease in the future. In addition, there currently are no therapies available to stop or slow down the progression in patients who are in this prodromal phase. Thus, further research is imperative not only to find better ways to recognize patients at an early stage, but also to provide neuroprotective therapies at a stage when therapies might be most effective.

Shahin Shirzadi, MD, was born in Pittsburgh, PA, attended the University of Houston after completing high school in Houston. He then went on to earn his doctorate degree from Texas Tech University in Lubbock, TX. Subsequently, he completed his internship in Internal Medicine at the University of Texas Medical Branch in Galveston, and completed his residency at the University of Texas Health Science Center in Houston, TX. In 2000, Dr. Shirzadi completed his fellowship in Neurophysiology. He became Board Certified in Neurology in 2000. He has many clinical interests including movement disorders. He is a member of many professional and scientific organizations as well as the Houston Area Parkinson Society's Medical Advisory Board.

PRODROMAL PARKINSON'S by Shahin Shirzadi, MD

central

DANCE

Mondays 12:30-1:30 pmHouston Ballet Center for Dance

601 Preston Houston, TX 77002

Text HAPS001 to 51555

Presented in partnership with Houston Ballet

SINGING

2nd and 4th Mondays 1:45-2:45 pmHouston Ballet Center for Dance

601 Preston Houston, TX 77002


Presented in partnership with Houston Ballet

TAI CHI

Tuesdays 10:30-11:30 amMetropolitan Multi-Service Center

1475 West Gray - Room 2 Houston, TX 77019


TANGO

Wednesdays 1:00-2:15 pmMetropolitan Multi-Service Center

1475 West Gray - Gym Houston, TX 77019


MUsic therapy & EXERCISE

Tuesdays 1:30-3:30 pmCrosspoint Church

4601 Bellaire Blvd. - Loft Bellaire, TX 77401


EXERCISE

Thursdays 9:45-10:45 amMetropolitan Multi-Service Center

1475 West Gray - Gym Houston, TX 77019


Brain & Body class

Tuesdays 10:00-11:00 am Class content changes weekly.

Call for more information.St. John's United Methodist Church

400 Jackson Street - Wendt Hall Richmond, TX 77469


central

BOXING

Wednesdays Class 1 - 9:45-10:45 am

Class 2 - 11:00 am-12:00 pmMetropolitan Multi-Service Center

1475 West Gray - The Gym Houston, TX 77019

Paperwork and assessment are required. Both classes are currently full. Contact

HAPS for more information.Text HAPS005 to 51555

HAPS PD EXERCISE & SUPPORT GROUPS—MARCH 2019

all groups are free of charge. Please call the haps office to confirm group times and locations at 713-626-7114 or 713-313-1652.

Music therapy & TAI CHIFridays 10:00 am-12:00 pm

Memorial Drive Presbyterian Church11612 Memorial Drive - Room 102

Houston, TX 77024Text HAPS024 to 51555

tai chiThursdays 10:00-11:00 am

St. Martin’s Lutheran Church1123 Burney Road

Sugar Land, TX 77498Text HAPS014 to 51555

EXERCISEFridays 10:00-11:00 am

Sugar Land Baptist Church16755 SW Freeway - Room 107


EXERCISE Mondays 10:00 am-11:00 pm

First United Methodist Church3900 Lexington Blvd. at FM 1092

Missouri City, TX 77459Text HAPS012 to 51555

CAREGIVER WELLNESS CLASS

Fridays 10:00-11:00 amSugar Land Baptist Church

16755 SW Freeway - Room 106 Sugar Land, TX 77479


southwest

MUSIC THERAPY & EXERCISETuesdays 10:00 am-12:00 pm



SPEECH & EXERCISEWednesdays 2:30-4:00 pm



CENTRAL west


yoga

Mondays 11:00 am-12:00 pm St. Stephen's United Methodist Church

2003 West 43rd Street - Rm 101Houston, TX 77018


North

SPEECH & ExerciseMondays 1:00-2:45 pmCHI St. Luke's Hospital

17200 St. Luke's Way - Lakeview A The Woodlands, TX 77384


EXERCISE Thursdays 1:30-2:30 pm

Woodlands United Methodist Church2200 Lake Woodlands Drive The Woodlands, TX 77380


Northwest

EXERCISEMondays 10:00-11:00 am

Lakewood United Methodist Church11330 Louetta Road Houston, TX 77070


EXERCISETuesdays 1:45-2:45 pm

Encompass Rehab Hospital of Cypress13031 Wortham Center Drive

Houston, TX 77065Please call, class space is limited.


SPEECHThursdays 10:30-11:30 am

John Wesley United Methodist Church5803 Bermuda Dunes Houston, TX 77069


TAI CHIFridays 11:00 am-12:00 pm

Tomball United Methodist Church1603 Baker Drive - Faith Building

Tomball, TX 77375Text HAPS036 to 51555

EXERCISEWednesdays 10:00-11:00 am

Richard & Meg Weekley Community Center

8440 Greenhouse Road - Room 200 Cypress, TX 77433


EXERCISEWednesdays 1:00-2:00 pm

The Luke Church2380 S. Houston Ave. - Room D

Humble, TX 77396Text HAPS038 to 51555

SPEECH & EXERCISETuesdays 4:30-6:00 pm

First United Methodist Church of Katy5601 5th Street at Ave. A - Fellowship Hall

Katy, TX 77493Text HAPS025 to 51555

MUSIC THERAPY

Thursdays 1:00-2:00 pmLiving Word Lutheran Church

3700 South Mason Road - Micah Room Katy, TX 77450


WATER EXERCISETuesdays and Thursdays 9:00-10:00 am

Bay Area Rehabilitation Center5313 Decker Drive Baytown, TX 77520


Call the HAPS office. Paperwork required.

EXERCISETuesdays 1:30-2:30 pmAlvin Lutheran Church

1800 FM 1462 Alvin, TX 77511


EXERCISEWednesdays 4:00-5:00 pm

St. Andrew’s Episcopal Church2535 E. Broadway, FM 518

Pearland, TX 77598Text HAPS019 to 51555

EXERCISE

3rd Thursday 2:00-3:00 pmFirst United Methodist Church

200 W Highway 517 - Gym Dickinson, TX 77539


east

Speech & exercise

Speech - Tuesdays only 2:45-3:45 pm Exercise - Tuesdays & Thursdays

3:45-4:45 pmKindred Hospital Bay Area

4801 E. Sam Houston Parkway South Pasadena, TX 77505

Text HAPS010 to 51555 (Tue)Text HAPS011 to 51555 (Thu)

southeast

south

water exerciseWednesdays 12:00-1:00 pm

Mansion Villas 15223 Scenic ForestConroe, TX 77384

Text HAPS028 to 51555 Call the HAPS office. Paperwork required.

Northeast

TAI CHIMondays 11:00 am-12:00 pm

Tracy Gee Community Center3599 Westcenter Drive


west

exercise

NOT CURRENTLY MEETINGFirst Baptist Church

18525 N 6th Street/Buddy Riley Blvd Magnolia, TX 77354



EXERCISE & SpeechWednesdays 1:00-3:00 pm

Gloria Dei Lutheran Church18220 Upper Bay Road - Life Center


support groups

PLEASE CONTACT THE HAPS OFFICE FOR MARCH SUPPORT GROUP SCHEDULES

To help you find the most appropriate support group, contact a HAPS social worker prior to attending a support group at 713-626-7114, 713-313-1706 or [email protected].

PD SUPPORT GROUP CHAMPIONS

1st Wednesday 2:30-4:00 pm

John Wesley United Methodist Church5830 Bermuda Dunes Houston, TX 77069


PD SUPPORT GROUP WILLOWBROOK

1st Wednesday 6:00-7:30 pm

Methodist Willowbrook Hospital18200 Tomball Parkway - Aspen Room


CAREGIVER SUPPORT GROUP CHAMPIONS

2nd Thursday 10:30-11:30 am

John Wesley United Methodist Church5830 Bermuda Dunes - 2nd floor Board Rm


PD SUPPORT GROUP KATY

1st Thursday 10:00-11:30 amMemorial Hermann Hospital

23900 Katy Freeway - Ram Room Katy, TX 77494


SUPPORT GROUPS THE WOODLANDS

2nd Thursday

Patient Group 12:15-1:15 pm Caregiver Group 1:30-2:30 pm

Woodlands United Methodist Church2200 Lake Woodlands Drive The Woodlands, TX 77380


PD SUPPORT GROUP KINGWOOD

3rd Thursday 1:00-2:30 pmKingwood United Methodist Church

1799 Woodland Hills Drive - Room K105 Kingwood, TX 77339


NEWLY DIAGNOSED SUPPORT GROUP

3rd Monday

For those diagnosed with PD within the last three years. Please call for details.

PD SUPPORT GROUP CENTRAL AM

3rd Tuesday 10:00-11:30 am

American Red Cross2700 SW Freeway Houston, TX 77098


PD SUPPORT GROUP SUGAR LAND

3rd Tuesday 6:00-7:30 pm

Houston Methodist Sugar Land Hospital16655 SW Freeway - Main Conf. Rm B


CAREGIVER SUPPORT GROUP CENTRAL

3rd Wednesday 2:30-4:00 pm

Memorial Drive Presbyterian Church11612 Memorial Drive


PD & DEMENTIA/LEWY BODY CAREGIVER SUPPORT GROUP

4th Monday 10:00-11:30 am

For caregivers of those with PD and dementia or Dementia with

Lewy Bodies.

CAREGIVER SUPPORT GROUP CLEAR LAKE

1st Wednesday 1:00-2:30 pmGloria Dei Lutheran Church

18220 Upper Bay Road - Kid Zone Houston, TX 77058


PD SUPPORT GROUPmagnolia

ON HOLD UNTIL FURTHER

NOTICE after exercise

First Baptist Church 18525 N 6th Street/Buddy Riley Blvd

Magnolia, TX 77354Text HAPS213 to 51555

PD SUPPORT GROUPPEARLAND

4th Wednesday 2:30-3:45 pm

St. Andrew’s Episcopal Church2535 E. Broadway, FM 518

Pearland, TX 77598Text HAPS214 to 51555

caregiver SUPPORT SUGAR LAND

3rd Friday 10:00-11:00 am

Sugar Land Baptist Church16755 SW Freeway - Room 106



Atypical Parkinson's SUPPORT GROUP

3rd Thursday10:00-11:00 am

American Red Cross2700 SW Freeway Houston, TX 77098



save the date

THURSDAY APRIL25Annual Parkinson’s Awareness Month Event!

L O T E R I A ! ( M e x i c a n B i n g o )

(Details to follow)

Now on l i n e !You can now access the video recorded sessions from the HAPS 7th Caregiver Conference: caring for self and others on the website at www.hapsonline.org. Archived sessions include:

What is Parkinson's Disease Dementia Michele York, PhD, ABPP-CN The Things You Don't See Joohi Jimenez-Shahed, MD Living with Low Blood Pressure Olga Waln, MD Mobility Challenges: Some Answers to Your Questions Betty MacNeill, PT, DPT

brain & bodyparkinson’s

class

St. John's United Methodist Church 400 Jackson Street–Wendt Hall

Richmond, TX 77469

TUESDAYS FROM 10:00-11:00 AM

Join us for a weekly class that provides participants with an environment to experience and learn new things– sometimes using their bodies and sometimes challenging their brains.

This holistic framework provides unique opportunities for individuals to explore various approaches such as engaging socially through games and connecting with others; incorporating complementary disciplines such as meditation and art; and practicing more traditional symptom management modalities such as tai chi, physical exercise and speech therapy. Every Tuesday, this class offers one activity which varies from week to week.


COFFEE AND PARKINSON'S: PROTECTION IN THE MAKING

For years, drinking coffee has been associated with having a reduced risk of developing Parkinson's disease (PD). In fact, a 1968 study suggested that coffee drinkers were less like to get PD (Nefzger, Quadfasel, & Karl, 1968). Since then, multiple epidemiologic studies have confirmed the PD/coffee connection (Ascherio et al., 2003; Ascherio et al., 2004; Fujimaki et al., 2018). Researchers have mostly attributed the protective effect to the caffeine component (Lee et al., 2013).

However, coffee is more than a caffeine delivery system. Coffee has more than 1,000 different compounds, including organic acids, sugars, amino acids and fatty acids. One such fatty acid called Eicosanoyl-5-hydroxytryptamide (EHT) has been getting quite a bit of buzz in the PD research community; and, for good reason. A recently published study titled, “Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson’s disease and DLB” (Yan et al., 2018), provides some compelling insights into the possible biochemical protective mechanisms of our cup of joe. A recently published study in the journal, Neuropsychopharmacology, sought to determine if having ADHD and/or its treatment, increases the risk of having basal ganglia and cerebellar diseases. In this 20-year follow-up retrospective cohort study, a total of 190,586 patient records (31,796 with ADHD and 158,790 without ADHD) from Utah were examined. People with no prior PD diagnosis or symptoms, no basal ganglia/cerebellar disease and those with a history of substance abuse were excluded from participating in the study.

Here’s what the researchers did: over a six-month period, they treated groups of two different PD model mice with various combinations of caffeine and EHT (caffeine alone, EHT alone, or caffeine and EHT together) to study their effects on both brain and behavior. There was also a group of mice that received no treatment. Then they performed several behavioral tests to study their movement, as well as study their brains for signs of alpha-synuclein clumps (which result in Lewy bodies, the pathological hallmark of PD), neurodegeneration and inflammation. The study found that the untreated mice had significant amounts of clumped α-synuclein in their brains, increased inflammation and loss of neurons, as well as significant deficits on three different behavioral tests. In general, the mice treated with EHT or caffeine alone showed either no or minimal improvement in any of these measures. However, the mice treated with the combination of EHT and caffeine together showed significant improvements in all of these measures.

ResultsMore specifically, mice treated with both EHT and caffeine together:• Had less alpha-synuclein clumping in the brain• Maintained better neuron integrity and function• Had less brain inflammation• Displayed less movement symptoms

What Does This Mean?In this study, a synergistic combination of EHT and caffeine was shown to slow down the progression of the neurodegeneration associated with PD in mice — which

has potentially readily available therapeutic implications. In addition, previous research has demonstrated that caffeine enhances dopamine signaling in the brain (Volkow et al., 2015); and, it’s the death of dopamine-producing cells that results in movement symptoms of PD (and why dopamine replacement medication is the gold standard treating PD symptoms).

For years, coffee consumption has been suggested to play a protective role in developing PD. However, it was never clear what exactly in coffee had this effect. This study suggests that two compounds, caffeine and the fatty acid EHT, work together to protect against alpha-synuclein clumps and dopamine neuron loss in two different PD models of mice. Interestingly, these effects were seen even using very low doses of the compounds. If the results of this study can be replicated by other researchers, then identifying that delicate balance of safety and effectiveness for humans is likely an essential step that researchers will be investigating in the future.

References:Ascherio, A., Chen, H., Schwarzschild, M. A., Zhang, S. M., Colditz, G. A., & Speizer, F. E. (2003). Caffeine, postmenopausal estrogen, and risk of Parkinson's disease. Neurology, 60(5), 790-795.Ascherio, A., Weisskopf, M. G., O'Reilly, E. J., McCullough, M. L., Calle, E. E., Rodriguez, C., & Thun, M. J. (2004). Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: the modifying effects of estrogen. Am J Epidemiol, 160(10), 977-984. doi:10.1093/aje/kwh312Chang, K. L., & Ho, P. C. (2014). Gas chromatography time-of-flight mass spectrometry (GC-TOF-MS)-based metabolomics for comparison of caffeinated and decaffeinated coffee and its implications for Alzheimer's disease. PLoS One, 9(8), e104621. doi:10.1371/journal.pone.0104621Collaborators, G. B. D. P. s. D. (2018). Global, regional, and national burden of Parkinson's disease, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol, 17(11), 939-953. doi:10.1016/S1474-4422(18)30295-3Fujimaki, M., Saiki, S., Li, Y., Kaga, N., Taka, H., Hatano, T., Hattori, N. (2018). Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease. Neurology, 90(5), e404-e411. doi:10.1212/WNL.0000000000004888Lee, K. W., Im, J. Y., Woo, J. M., Grosso, H., Kim, Y. S., Cristovao, A. C., Mouradian, M. M. (2013). Neuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's disease. Neurotherapeutics, 10(1), 143-153. doi:10.1007/s13311-012-0165-2Nefzger, M. D., Quadfasel, F. A., & Karl, V. C. (1968). A retrospective study of smoking in Parkinson's disease. Am J Epidemiol, 88(2), 149-158.Vicente, S. J., Ishimoto, E. Y., & Torres, E. A. (2014). Coffee modulates transcription factor Nrf2 and highly increases the activity of antioxidant enzymes in rats. J Agric Food Chem, 62(1), 116-122. doi:10.1021/jf401777mVolkow, N. D., Wang, G. J., Logan, J., Alexoff, D., Fowler, J. S., Thanos, P. K., Tomasi, D. (2015). Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain. Transl Psychiatry, 5, e549. doi:10.1038/tp.2015.46Yan, R., Zhang, J., Park, H.-J., Park, E. S., Oh, S., Zheng, H., Mouradian, M. M. (2018). Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB. Proceedings of the National Academy of Sciences, 115(51), E12053-E12062. doi:10.1073/pnas.1813365115

This article is reprinted in its entirety with permission from Parkinson's Foundation and can be found at www.parkinson.org/blog.

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IN MEMORY

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PD101

Newly Diagnosed Education ProgramAn educational program for those who have been diagnosed with Parkinson’s within the last three years, this program offers an introductory look at the disease, treatment options and proactive disease management strategies. The program is offered five times a year with each session presented by a different movement disorder specialist.

Space is limited. Registration is required. Contact the HAPS office at 713-626-7114 or [email protected]. Made possible by UCB.

Presented by Erin Furr Stimming, MD

Saturday, April 6th

8:30 am - 12:30 pm

Board of Directors

Pamela Skaufel President Chris Brewster Vice President/Treasurer Mimi Prioleau Vice President/Secretary

Chris BellRon BernellNina P. BrownJoiner Cartwright, Jr., PhDRich CliffordAnne Jones CocoRobert CruikshankMeredith CullenJo FurrGreg Groogan

Ellin Grossman, EdDHarriet HartJosh HussKamden KanalyRob KerrLiz LaryHarriet LatimerDan LauckRobert A. MartoneQuin McWhirter

Joohi Jimenez-Shahed, MD ChairMadhureeta Achari, MDLeanne Burnett, MDBrian Dalm, MDAlbert Fenoy, MDErin Furr Stimming, MDJoseph Jankovic, MDEugene C. Lai, MD, PhDLaura Marsh, MD

Kathleen Crist, LMSW Executive Director

Celeste Harris, LMSW Director of Social Services

This publication is not intended to provide diagnosis or treatment. Always seek the advice of your physician or pharmacist with questions regarding medical conditions or drug interactions. To request permission to reprint content published in this newsletter, please contact the HAPS office at 713-626-7114 or [email protected].

Joe AhmadFrank Donnelly, Jr.William FinnornPhilip FrancisTom GanucheauDaphne Haskin

Mike HendryxJeff HurlbertLeon KeebleCaroline Kerr Renju Jose KuruvilaJose M. Oti

Gerald RideauxErick SandlinIzzy SchulteDavid StuyckJim ThorpStephanie Zamora

Board of advisors medical advisory board

Greg McLauchlin, MDKimberly Monday, MDWilliam Ondo, MDTerry K. Satterwhite, MDMya Schiess, MD Shahin Shirzadi, MDDesirée B. Thomas, MDAshwin Viswanathan, MDToby Yaltho, MDMichele York, PhD, ABPP-CN

Jim NicklosW.O. Neuhuas IIIMalcolm PettigrewGeorge PuigJeff RosenbergArthur SchechterJoyce Proler SchechterLeslye Weaver Michael YoungGabriel Zamora

staff

Maggie Abbott, PT, DPT Director of Education

Angelica Rodriguez Manager of Therapeutic Programs

Madelyn Perry Manager of Special Events

Gini Brown Administrative Assistant

the haps impact march 2019

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