the heart cardiology. physical characteristics situated between the lungs in the mediastinum about...
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The Heart
Cardiology
Physical Characteristics Situated between the lungs in the
mediastinum About the size of a clenched fist Cone or pyramid shape, tilting to
the left Apex - inferior portion Base - superior portion
Pericardium - 3 layers Fibrous pericardium - outer layer Serous pericardium - inner layer
parietal layer visceral layer (epicardium)
Pericardial cavity - space between the parietal and visceral layers that is filled with pericardial fluid
Pericardial fluid - lubrication,reduces friction
Heart Wall Epicardium - outermost layer
visceral pericardium Myocardium - middle layer
cardiac muscle involuntary, striated, short, branched cells intercalated discs
Endocardium - inner layer lines the chambers and covers the valves simple squamous epithelium
Heart Chambers Two upper atria ; two lower ventricles Atria are the receiving chambers Ventricles are the distributing chambers Interatrial septum separates atria Interventricular septum divides
ventricles Auricles are external flaps Left ventricle very thick
Heart Valves Atrioventricular valves
tricuspid (right) bicuspid or mitral (left) chordae tendineae papillary muscle
Semilunar valves aortic semilunar pulmonary semilunar three pocketlike cusps
Valve Disorders Rheumatic Fever - group A, B-
hemolytic Streptococcus pyogenes Heart Mumur
stenosis incompetent valves Mitral valve prolapse (MVP)
Blood Flow through the Heart
The heart receives blood from the superior vena cava, inferior vena cava and the coronary sinus
Right atrium->tricuspid valve->right ventricle-> pulmonary semilunar valve-> pulmonary trunk>pulmonary arteries-> lungs-> pulmonary veins->left atrium->mitral valve->left ventricle>aortic semilunar valve -> aorta
Pulmonary & Systemic Circulation
Pulmonary circulation - refers to blood going through the right side of the heart to the lungs
Systemic circulation - involves the left heart. Oxygenated blood from the lungs flows into the left atrium, enters the left ventricle, out through the aorta into the body’s tissue, and back via systemic veins to the right atrium
Coronary Circulation The aorta
branches into the left and right coronary arteries
Blood flow through myocardium
Left coronary artery Anterior interventricular artery Circumflex artery
Right coronary artery Posterior interventricular artery Marginal artery
Arterial anastomoses
Venous Drainage Great cardiac veins Coronary sinus Right atrium
Cardiac Conduction System
Sinoatrial (SA) node Pacemaker of the heart
Atrioventricular (AV) node Atrioventricular bundle (Bundle of His) Left and right bundle branches Purkinje fibers Modification by the ANS and hormones
Cardiac Physiology
Electrocardiogram - ECG P wave - atrial depolarization QRS complex - ventricular
depolarization T wave - ventricular repolarization Atrial repolarization is masked by
the larger QRS complex
Arrhythmias Abnormal Heart Rhythms Heart block - blockage in the AV node Tachycardia - >100 beats per minute Bradycardia - <60 beats per minute Fibrillation - uncoordinated quivering Flutter - rapid contractions PVC - premature ventricular
contraction PAC - preatrial contraction
Terms Myocardial infarction (MI) - heart
attack Infarction - tissue death due to loss
of blood supply Ischemia - decreased blood flow
causing hypoxia Angina pectoralis - chest pain
related to coronary problems
Cardiac Cycle
Cardiac cycle consists of one complete cycle of contraction and relaxation
Contraction phase - systole Relaxation phase - diastole Complete cycle - 0.8 seconds Phases : relaxation period,
ventricular filling, ventricular systole Normal heart rate - 75 beats/minute
Cardiac Output CO = Stroke volume x Heart rate
Amount of blood passing through a ventricle in 1 minute
SV = Amount of blood that is pumped by a ventricle per beat (approx. 70 ml)
HR = number of beats per minute
Examples Rest - CO = 70ml/beat x 75 beats/min = 5250ml/minute =5.25 liters/minute Exercise - CO = 140ml/beat x 150 beats/min = 21,000ml/minute = 21 liters /minute
Factors influencing stroke volume
“Frank - Starling law of the heart” Critical factor = stretch of cardiac muscle Preload - how much blood enters a
ventricle during diastole Contractility - forcefulness of a contraction Afterload - pressure needed before
ventricle ejection occurs
Regulation of Heart Rate
Cardiovascular Center Medulla Sympathetic nervous
system Cardiac accelerator
nerves Parasympathetic
nervous system Vagus nerve
Baroreceptors - monitor pressure aortic arch carotid arteries
Chemoreceptors - monitor chemicals aortic/carotid
bodies Hormones, age,
fitness,gender