THE HISTORYOF INJECTABLES

THE REVOLUTION IN FACIAL REJUVENATION

Injectable treatments such as wrinkle fillers & wrinkle relaxers have

revolutionized facial rejuvenation. Collagen was the first FDA-approved filler in

1981, but was soon replaced with better, safer, longer-lasting fillers in the early

2000s. Here's a look at the history of these products.

WRINKLE RELAXERS WRINKLE FILLERS

Infographic by:

Sources:http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/CosmeticDevices/WrinkleFillers/ucm227749.htm

ZYDERM®

1981

ZYPLAST®

1985 1988 2002

2003200320042004

Hylaform®

2004 2006 2006 2006

2006200820082009

2009 2011 2011

20122013

FIBREL®

Cosmoderm®

CaptiqueTM elevessTM

PREVELLE® SILKEVOLENCE®

-LV O L U M ATM XC

wrinkle relaxers

wrinkle fillers

• Products relax muscles that cause wrinkles

• Products contain a purified form of neurotoxin

• Results develop within a few days to a week

• Results last from 3 to 6 months

• Products fill wrinkles and provide volume

• Products contain a variety of substances

• Results often seen immediately

• Results last from 6 months to several years, based on product