the intermediary reloaded

Download The Intermediary Reloaded

Post on 03-Nov-2014

236 views

Category:

Science

5 download

Embed Size (px)

DESCRIPTION

Opening Session - Keynote Address, CSA Trust Mike Lynch Award, at the Ninth International Conference on Chemical Structures, June 5th, 2011, Noordwijkerhout NL

TRANSCRIPT

  • 1. 9th Intl. Conf. Chem. Structures, June 5th, 2011 The Intermediary Reloaded On the Need for a "Go-Between" to Information Users and Producers Engelbert Zass Chemistry Biology Pharmacy Information Center ETH Zrich 8093 Zrich, Switzerland

2. 9th Intl. Conf. Chem. Structures, June 5th, 2011 3. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Prof. Dr. Dr .h.c. mult. Emanuel Vogel * 2.12.1927 31.3.2011 Gratefully dedicated to the memory of my first academic teacher 4. History of Searching about: -1970 print sources only 1970- isolated electronic sources for information specialists 1985- isolated electronic sources for chemists (end-users) 2000- integrated electronic sources for chemists 9th Intl. Conf. Chem. Structures, June 5th, 2011 4 5. 9th Intl. Conf. Chem. Structures, June 5th, 2011 5 Searching the Beilstein Handbook (1984) 6. Searching (1993) 9th Intl. Conf. Chem. Structures, June 5th, 2011 6 Librarian Online-"Specialist" End-User / Research group specialist Printed Sources CD-ROMs Public Online Databases (Data-Star, STN, DIALOG, ORBIT, CIS, Questel) Chemistry Library ETHZ Access to Chemical Information 7. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Searching (1998) Library Staff (Chemists) End-Users Printed Sources Public Online Databases (Data-Star, STN, DIALOG, ORBIT, CIS, Questel) ETH Chemistry Information Center Access to Chemical Information at InfoCenter "at the bench" "Electronic Library" CD-ROMs In-house Databases at InfoCenter 8 Licence Control 8. Problems in End-User Searching Insufficient education and experience Searches are often executed in the best known/easiest accessible, not in the most appropriate source New user interfaces often hide old data structures & indexing policies problems of content & coverage Availability of databases at the bench does not per se improve information access 9th Intl. Conf. Chem. Structures, June 5th, 2011 8 9. Goals in End-User Searching Enable chemists do do their own routine searches in appropriate sources Stimulate critical distance to searching What am I able to search on my own ? When do I need support for searching ? What do I have to delegate to specialists ? Select most suitable sources Formulate appropriate queries Evaluate search results critically 9th Intl. Conf. Chem. Structures, June 5th, 2011 9 10. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Problem Matrix Search procedure obvious ? Interface useful ? Data base appropriate ? Yes Yes Yes End User Search No Yes Yes Supported Search No No Yes Mediated Search No No No Instruction / Test Searches 11. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Service Matrix End User Search Support Supported Search Individual Coaching Training Mediated Search Search Service Instruction / Test Searches Education Individual Instruction 12. 9th Intl. Conf. Chem. Structures, June 5th, 2011 13. 9th Intl. Conf. Chem. Structures, June 5th, 2011 13 Roles of an Intermediary Support of Users Education & Training of Users Search Services Evaluation & Testing of Sources Licensing & Propagation (meta info) Feedback to Producers: identifying problems developping bypasses suggesting solutions 14. 9th Intl. Conf. Chem. Structures, June 5th, 2011 14 Disclaimer Some people in the audience will probably not like several of the conclusions drawn from the search examples shown but XX 15. Support of Users Catalogs (Web OPAC) Navigational Help (GIS) Meta Databases General Services Personal Services WYNIWYG: what you need is what you get 9th Intl. Conf. Chem. Structures, June 5th, 2011 15 16. Locate J. Comput. Chem. 9th Intl. Conf. Chem. Structures, June 5th, 2011 16 17. Fast Track to e-Journals 9th Intl. Conf. Chem. Structures, June 5th, 2011 17 18. ETH Central Library Knowledge Portal 9th Intl. Conf. Chem. Structures, June 5th, 2011 18 19. Clemenceau Paraphrase (1) La guerre ! Cest une chose trop grave pour la confier des militaires Chemical Information: too important to leave it to Central Libraries Flourish. Enter (after Shakespeare): Chemical Information Specialist 9th Intl. Conf. Chem. Structures, June 5th, 2011 19 20. 9th Intl. Conf. Chem. Structures, June 5th, 2011 20 Meta Databases: Patent Sources 21. Education & Training 9th Intl. Conf. Chem. Structures, June 5th, 2011 21 22. 9th Intl. Conf. Chem. Structures, June 5th, 2011 23. Integrated Bachelor Courses 9th Intl. Conf. Chem. Structures, June 5th, 2011 http://www.infochembio.ethz.ch/kurse_chemie.html 24. Tailored Special Courses 9th Intl. Conf. Chem. Structures, June 5th, 2011 25. Master/Ph.D. Level 9th Intl. Conf. Chem. Structures, June 5th, 2011 26. 9th Intl. Conf. Chem. Structures, June 5th, 2011 27. Search Services 9th Intl. Conf. Chem. Structures, June 5th, 2011 27 28. Request: Phase Diagram for B2O3-V2O5 Not found in: Springer Materials (Landolt-Brnstein) Reaxys SciFinder 9th Intl. Conf. Chem. Structures, June 5th, 2011 28 29. 9th Intl. Conf. Chem. Structures, June 5th, 2011 30. 9th Intl. Conf. Chem. Structures, June 5th, 2011 30 All three references indexed by CAS, but irretrievable by conceivable queries 31. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Search Services: Chemical Abstracts Complex (precise, comprehensive) Topic Searches (by Keyword) Boolean & Proximity Operators Truncation (more) Roles Lexikon Specific Data Fields Composition of Compounds (Materials) Sequences of Biopolymers 32. NOE Difference Spectroscopy 9th Intl. Conf. Chem. Structures, June 5th, 2011 32 33. 9th Intl. Conf. Chem. Structures, June 5th, 2011 SciFinder (4.6.2010) 34. 9th Intl. Conf. Chem. Structures, June 5th, 2011 34 cf. SciFinder: 7 ! 35. 9th Intl. Conf. Chem. Structures, June 5th, 2011 35 Citation Searching J. Am. Soc. Inf. Sci. Technol. 53, 12101215 (2002) 36. Multifile Citation Search: CA + SCI 9th Intl. Conf. Chem. Structures, June 5th, 2011 36 37. ETH InfoCenter: STN Expenses 9th Intl. Conf. Chem. Structures, June 5th, 2011 37 0.00 2000.00 4000.00 6000.00 8000.00 10000.00 12000.00 14000.00 16000.00 Expenses(EUR) 1995 1997 1999 2001 2003 2005 2007 2009 Year 1995: CrossFire 2002: SciFinder Scholar 38. 9th Intl. Conf. Chem. Structures, June 5th, 2011 38 Roles of an Intermediary Support of Users Education & Training of Users Search Services Evaluation & Testing of Sources Licensing & Propagation (meta info) Feedback to Producers identifying problems developping bypasses suggesting solutions 39. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Meta Information: Database Content 40. 9th Intl. Conf. Chem. Structures, June 5th, 2011 CASREACT (STN): Documents 41. 9th Intl. Conf. Chem. Structures, June 5th, 2011 CASREACT (SciFinder): Reactions 42. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Reaxys: Content Gmelin Gmelin database sources: printed handbook 1924-1975 248 vols. (1924-1975) in database 512 vols. (1976-1997) NOT in database instead 112 journals 1976- 43. 9th Intl. Conf. Chem. Structures, June 5th, 2011 43 Reaxys: Recent Update 44. 9th Intl. Conf. Chem. Structures, June 5th, 2011 44 Point of Attachment: before Update 45. 9th Intl. Conf. Chem. Structures, June 5th, 2011 45 Point of Attachment: after Update 46. 9th Intl. Conf. Chem. Structures, June 5th, 2011 46 Comparison: Substructure Search Repeating Groups VPA (variable points of attachment) 47. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Repeating Groups and VPAs such entered do not work in a Reaxys search ! 48. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Comparison of Literature Coverage 49. 9th Intl. Conf. Chem. Structures, June 5th, 2011 49 Comparison: Steps of Total Syntheses Dysidiolide (6/2009) Reaxys SFS CASREACT longest sequence commercial start. longest sequence commercial start. Waldmann 2002 "multistep" 3 of 3 14 7 of 10 (0 of 3) Forsyth 2002 20 8 of 8 19 8 of 10 (1 of 2) Yamada 2001 15 3 of 6 (2 of 3) 23 9 of 13 (2 of 4) Yamada 2000 22 10 of 12 (2 of 2) 1 0 of 2 (1 of 2) Forsyth 2000 18 7 of 9 (2 of 2) 17 7 of 9 (1 of 2) Shirai 2000 THL 17 10 of 10 15 10 of 10 Shirai 2000 BMCL 5 5 of 6 (1 of 1) 4 4 of 5 (1 of 1) Danishefsky 1998 10 3 of 6 (3 of 3) not found not found Boukouvalas 1998 13 6 of 8 (1 of 2) not found not found Corey 1997 24 9 of 10 (1 of 1) 3 0 of 1 50. E. Zass, Forum Molekulare Wissenschaften, 2.6.2010 50 51. 9th Intl. Conf. Chem. Structures, June 5th, 2011 51 52. 9th Intl. Conf. Chem. Structures, June 5th, 2011 52 53. Books by Gisbert Schneider 9th Intl. Conf. Chem. Structures, June 5th, 2011 53 54. SciFinder: MnSO4 E. Zass, InfoZentrum Chemie Biologie Pharmazie, FS 2011 54 55. CA: Salts dot.disconnect + Hill E. Zass, InfoZentrum Chemie Biologie Pharmazie, FS 2011 55 56. Chalkogen Acids: acidic H kept ! E. Zass, InfoZentrum Chemie Biologie Pharmazie, FS 2011 56 57. E. Zass, InfoZentrum Chemie Biologie Pharmazie, FS 2011 57 dot.disconnect: Normalization BexHy(PO4)z Be3(PO4)2 Be(H2PO4)2 BeHPO4 58. 9th Intl. Conf. Chem. Structures, June 5th, 2011 58 Reaxys: BxFyOz 59. E. Zass, InfoZentrum Chemie Biologie Pharmazie, FS 2011 59 A Legacy to Keep in SciFinder: Analyses 60. E. Zass, InfoZentrum Chemie Biologie Pharmazie, FS 2011 60 61. 9th Intl. Conf. Chem. Structures, June 5th, 2011 61 62. CrossFire Gmelin: Composition Element Symbol No. of Elements No. of Components not available any more in Reaxys ! 63. 9th Intl. Conf. Chem. Structures, June 5th, 2011 SciFinder (Scholar): Warning ??? 64. 9th Intl. Conf. Chem. Structures, June 5th, 2011 64 Problem: SciFinder Explore by Topic 65. 9th Intl. Conf. Chem. Structures, June 5th, 2011 65 SciFinder: Variants ? 66. 9th Intl. Conf. Chem. Structures, June 5th, 2011 66 67. 9th Intl. Conf. Chem. Structures, June 5th, 2011 Problem: First Total Synthesis of Estrone Search via Structure: 2011 2004 total synthesis 1948 1967 Search via Keyword (trivial name): estron total synt

View more >