the internet for social machines - choose your...
TRANSCRIPT
(2005)
Which Gene Did You Mean?why bury it first and then mine it again?
What does FAIR eventually entail?The Machine knows what I mean
(2018)
The Internet of FAIR data and Services
The Internet for Social MachinesThe end of data sharing as we know it
Lorentz
FAIRdICT
EOSC
IFDS
Birth Infancy Adolescence Maturity
2014 2015 2016 2017 2018…
FAIR and GO FAIR
Prof. Dr. Barend Mons
DirectorGO FAIR International Support and Coordination Office
Visiting address: Poortgebouw N-01, Rijnsburgerweg 10, 2333 AA Leiden,The Netherlands, E-mail: [email protected], Mobile: +31 6 24879779, Skype: dnerab
www.go-fair.org
Primary use
Secondary use
Research and care data are not ‘technically’ different
Health care managers
other Health care
professionals
Health researchers
Goverment Commercial / innovation
Population
Health care professionals
Healthcare
Health research
Public health management
Management, financial, politics
Analytics and Statistics
Quality and process improvement
Innovation & commercial development
artifical barriersartifical barriers
Primary use
Secondary use
Care and research data should be dovetailed
Health care managers
other Health care
professionals
Health researchers Goverment
Commercial / innovation
Population
Health care professionals
Healthcare
Health research
Public health management
Management, financial, politics
Analytics and Statistics
Quality and process improvement
Innovation & commercial development
dovetailingdovetailing
12
Challenges with secondary use of health data
Access to data involves significant legal, organisational and technical hurdles
Burdensome registration for health care professionals - limited benefits from (multiple) registration
Low semantic and technical interoperability
Technical debt/legacies
Lack of basic, broad purpose common infrastructure and broadly accessible analytical capabilities
schemaof
required data
schemaof
required data
Formof
required data
datasteward
EHR 1
EHR 1
DICA
§
research
archive
biobank
savesave
reuseforany
purpose
schemaof
required data
schemaof
required data
Formof
required data
datasteward
EHR 1
EHR 1
DICA
§
research
archive
biobank
savesave
reuseforany
purposeFAIR
FAIR
ss pp oo
UPRIUPRI
provenanceprovenance
A nanopublication is the smallest meaningful assertion, minimally one Subject-Predicate-Object tripleS,P, & O are all concepts and thus all have Unique, Persistent and Resolvable Identifiers. Many nanopublications are small graphs with multiple triples forming the assertion
ss pp oo
UPRIUPRI
provenanceprovenance
Two nanopublications representing the same meaningful assertion, i.e. the Subject-Predicate-Object triples are identicalmay have different provenance (they come from different sources)They each have their Persistent and resolvable Identifier. and different provenance graphs
ss pp oo
UPRIUPRI
provenanceprovenanceUPRIUPRI
provenanceprovenance
A Cardinal Assertion is one assertion that is linked to 1-n provenance graphs (up to thousands in some cases)
A
B
C
5 objects are shared between all three knowlets (in this case: metabolic syndrome, diabetes, and e.o Alzheimer)
Aconceptual similarity
(hypothesis generation)
Cconceptual drift
(meta-data/blockchain)
DQUA’s
(semantic bias)
The value of knowlets in dynamic ontological graphs
BNear sameness
(semantic lenses)
UPRI
UPRI
URI
Hospital 1Hospital 1UPRI
Hospital 2Hospital 2
Hospital nHospital n
Thyroid Gland <> COPD?
Pubmed: no
Thyroid Gland <> COPD
196.425 K patients
Thyroid Gland <> COPD?
EURETOS: YES
Thyroid Gland <> COPD?
DICA: measure!Measure CLCX13
Measure CLCX13
Measure CLCX13
predispositon? CLCX13
Thyroid Gland <> COPD?
doctors: no
UPRI
UPRI U
PRI
UPRI
UPRI
UPRI
UPRI
UPRI
UPRI
UPRI U
PRI
UPRI
UPRI
UPRI
pathwaypathwayworkflowworkflow
The Internet of Data and Services (PHT model)controlled at two levels: UPRI’s and a web of associative Knowletsrepresenting abstract concepts, digital objects (including distributed VMs) and physical objects, devices & things in a universal way with
scalable, unique, resolvable identifiers at is core.
UPRI
UPRI MEGA
UPRIUPRI
other metadata
data set
UPRIUPRI
other metadata
curated database
UPRIUPRI
other metadata
workflow
UPRIUPRI
other metadata
smartwatch
similarity measuresimilarity measure
UPRI
preferred term
definition
symbols used
The Internet….The end of data sharing a s we know it
from data sharing to data visiting in
The Internet for Social Machines