the national kidney foundation’s kidney early evaluation program tm “the greater new york...
TRANSCRIPT
The National Kidney The National Kidney Foundation’s Kidney Early Foundation’s Kidney Early
Evaluation ProgramEvaluation ProgramTMTM
““The Greater New YorkThe Greater New York Experience”Experience”
Ellen H. Yoshiuchi, MPSDivision Program Director
National Kidney Foundation Serving Greater New York
Kidney EarlyKidney EarlyEvaluation ProgramEvaluation ProgramTMTM
www.keeponline.org
KEEP ObjectivesKEEP Objectives
• Identify those at risk for Chronic Kidney Disease (CKD) using inclusion criteria:– Hypertension – Diabetes – Family history in first order relatives of
hypertension, diabetes or chronic kidney disease
• To empower individuals to prevent or delay the onset of CKD or renal failure through education and appropriate disease management
Chronic Kidney Disease Is a Chronic Kidney Disease Is a Public Health Problem!Public Health Problem!
• 26 million Americans have CKD. Most don’t know it.
• The devastating consequences of CKD are End Stage Renal Disease (ESRD), which requires dialysis or transplantation, or cardiovascular disease & death.
• Early screening, diagnosis, and treatment should delay or prevent death and ESRD.
• CKD is a worldwide public health problem.
New York State Impact
• An estimated 1.2 million New Yorkers are affected by CKD.
• The Center for Disease Control (CDC) reports a 116% increase in CKD in NYS over the past decade.
• In cost related to CKD, NYS is the 4th highest state at $2.9 billion.
• 7,300 New Yorkers will advance to End Stage Renal Disease (ESRD) annually.
• The diabetic CKD prevalence rate has increased from 6.2% to 7.6% from 2000 to 2006.
• Primary Causes of ESRD– Diabetes 40.5%– Hypertension 24%
KEEP OVERVIEW
• KEEP is a free public health screening program.• It was initiated in New York City by the National
Kidney Foundation in August of 2000.• Screenings are held in all areas of the US by local
National Kidney Foundation divisions or affiliates.• Over 160,000 people have been screened to
date. • Visit www.KEEPonline.org for more information.
Who Should Participate In KEEP?
Anyone age 18 or older with one or more of the following:
• History of diabetes• History of high blood pressure• Family history in first order relatives of
diabetes, high blood pressure and/or kidney disease.
(KEEP is not recommended for anyone on dialysis or for anyone who has had a kidney transplant.)
• Station One – Registration: Participant receives paperwork packet
• Station Two – Screening Questionnaire & Informed Consent: Filled out by a professional volunteer
• Station Three – Physical Measurements: Height, weight, waist circumference, BMI & blood pressure
• Station Four – Urine & Blood Testing• Station Five – Clinician Consultation: Interview
with a physician, nurse practitioner or physician assistant
• Station Six – Screening Review: Participants receive copy of informed consent & test results
Six Screening Stations
KEEP Screening EvaluationKEEP Screening Evaluation
Medical history DM HTN CVD CKD
Blood pressure Height and weight Waist circumference Body mass index (BMI) Blood glucose measurement Hemoglobin A1c (select
participants) Serum creatinine Hemoglobin
Albumin to Creatinine ratio eGFR-Estimated Glomerular Filtration Rate Lipid testing Total Cholesterol HDL/LDL/Triglycerides For eGFR<60 ml/min, Reflex Testing:
Calcium Phosphorus PTH-Parathyroid
hormone
Estimated GlomerularEstimated Glomerular Filtration Rate (eGFR) Filtration Rate (eGFR)
• Calculated based on serum creatinine test result, age, gender and ethnicity.
• Determines kidney function.
• Results sent to participant within 4 weeks, with a comprehensive report.
Blood Test: HemoglobinBlood Test: Hemoglobin
Used to determine anemia, which can be due to advanced Stages 3 to 5 or even low levels of kidney function.
KDOQI Classification of Anemia in CKD
Women <12.0 g/dl Anemia
Men <13.5 g/dl Anemia
AJKD May 2006
Reflex TestsReflex Tests
The following tests are conducted on the blood specimens of KEEP participants with an eGFR below 60:
•Calcium•Phosphorus•PTH
These tests assess bone health. Abnormal results may be related to kidney disease.
KEEP CRITERIA FOR HEMOGLOBIN A1cKEEP CRITERIA FOR HEMOGLOBIN A1c
Stages of CKDStages of CKD Stage Description GFR
(ml/min/1.732)
1 GFR Kidney damage and normal or GFR
90
2 Kidney damage and
Mild GFR
60-89
3 Moderate GFR 30-59
4 Severe GFR 15-29
5 Kidney Failure usually need dialysis
<15
KEEP in Greater New York
5 Years/62 Screenings2/1/2004 to 6/30/2009
• 4,944 attended the screenings.• 4,356 met inclusion criteria & completed
the screening.• Breakdown by gender
Male: 33.54% (1461) Female: 66.21% (2884)
Of the 4,356 who learned of a new problem…
• 2,538 learned they may have kidney disease: 58.26%
• 465 learned they may have diabetes:10.67%
• 555 learned they may have hypertension:12.74%
• 855 learned they may have high cholesterol: 19.63%
Of the 847 individuals who reported values for all 9 tests…
Values outside the normal range:• 23.14%--1 value• 25.27%--2 values• 20.54%--3 values• 9.45%--4 values• 78% of the 847 showed values outside the
normal range in 1 to 4 values.
All Asian
• 1,276 participants
• 1,056 met criteria
• 399 male
• 656 female
• 1 NA
• Asian 96%
• Caucasian & African American 4%
All Chinese: 95% Chinese800 participants/702 met criteria
• 252 Male: 35.90%• 449 Female: 63.96%• Individuals who were aware of a pre-
existing condition:• 50—kidney disease: 7.12%• 230—high cholesterol: 32.76%• 147—diabetes: 20.94%• 282—hypertension: 40.17%
Individuals who learned that they may have a new problem…
• Diabetes 13.82% (97)
• HTN 10.68% (75)
• Cholesterol 18.66% (131)
• CKD 58.83% (413)
Of the 103 individuals who reported values for all 9 tests…
Values outside the normal range:
• 24 individuals 23.30%--1 value
• 27 individuals 26.21%--2 values
• 17 individuals 16.50%--3 values
• 6 individuals 5.83%--4 values
• 2 individuals 1.94%--5 values
• 4 individuals 3.88%--6 values
Values Outside the Norm
• 80 individuals out of 103… reported one of more values outside the normal range
• 12 reported with 4 to 6 values outside the normal range