the past 2 decades of epi and nvi-v3nvi.ddc.moph.go.th/download/vc6/slide/03_1.pdf · 2014. 10....
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![Page 1: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/1.jpg)
๑ ทศวรรษ กบัการพฒันาวคัซีน และการสร้างเสริมภูมคิุ้มกนัโรค
ในประเทศไทยศุภมิตร ชุณหสุทธิวฒน
24 กรกฏาคม 2014
![Page 2: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/2.jpg)
มุมมอง
![Page 3: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/3.jpg)
1995 – 2004 2005 – 2014
National immunization program
Vaccine development & production
Policy coordination mechanisms
Para
llel t
imel
ines
Vaccine quality control & assurance
Disease and AEFI surveillance
![Page 4: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/4.jpg)
1995 – 2004 2005 – 2014
National immunization program
Vaccine development & production
Policy coordination mechanisms
Para
llel t
imel
ines
![Page 5: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/5.jpg)
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
![Page 6: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/6.jpg)
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
BCG
DTP
OPV
HB
JE
TT / dT
DTP-HB
M
MMR
Influenza
Neonatal Tetanus
0
20
40
60
80
100
0
20
40
60
80
100
1977 1981 1985 1989 1993 1997 2001 2005 2009
![Page 7: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/7.jpg)
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
BCG
DTP
OPV
HB
JE
TT / dT
DTP-HB
M
MMR
Influenza
Neonatal Tetanus
0
20
40
60
80
100
0
20
40
60
80
100
1977 1981 1985 1989 1993 1997 2001 2005 2009
![Page 8: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/8.jpg)
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
2010 vaccine supply by NHSO . --------------------
2011 pilot on Rota started in Sukhothai . ---------
2014 pilot on HPV started in Ayuthaya . --
Rescheduling & campaigns to cope with re-emergences
![Page 9: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/9.jpg)
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
2010 vaccine supply by NHSO . --------------------
2011 pilot on Rota started in Sukhothai . ---------
2014 pilot on HPV started in Ayuthaya . --
Rescheduling & campaigns to cope with re-emergences
![Page 10: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/10.jpg)
1995 – 2004 2005 – 2014
Vaccine development & production
Para
llel t
imel
ines
Mahidol maintaining continuous dengue vac development
GPO shifted JEV from Nakayama to Beijing strain GPO attempted LAV-JE, aborted
GPO stopped DTP to improve GMP
GPO constructingFlu manufacture
NSTDA & TCELS supporting dengue vac
GPO’s LAIV H1N1 licensed, H5N2 in clinical trials
TRCS maintaining BCG production TRCS upgrading BCG production
Bionet-Asia established as first private sector developer & producer, making continuous progress
Deve
lopm
ent
Prod
uctio
n GPO-MBP supplying EPI
Attempts on TB, Chik, EV7
Historical phase III HIV trial
![Page 11: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/11.jpg)
1995 – 2004 2005 – 2014
Vaccine development & production
Para
llel t
imel
ines
Mahidol maintaining continuous dengue vac development
GPO shifted JEV from Nakayama to Beijing strain GPO attempted LAV-JE, aborted
GPO stopped DTP to improve GMP
GPO constructingFlu manufacture
NSTDA & TCELS supporting dengue vac
GPO’s LAIV H1N1 licensed, H5N2 in clinical trials
TRCS maintaining BCG production TRCS upgrading BCG production
Bionet-Asia established as first private sector developer & producer, making continuous progress
Deve
lopm
ent
Prod
uctio
n GPO-MBP supplying EPI
Attempts on TB, Chik, EV7
Historical phase III HIV trial
Veterinary vaccine manufacture under DLD
National Bio-pharma Center
(NBF)
![Page 12: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/12.jpg)
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
![Page 13: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/13.jpg)
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
![Page 14: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/14.jpg)
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
![Page 15: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/15.jpg)
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
![Page 16: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/16.jpg)
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
1990’s - meetings & workshops on national mechanism for vaccine policy and capacity
NVC appointed by Cabinet , NVC secretary office in DDC/MOPH
![Page 17: The past 2 decades of EPI and NVI-v3nvi.ddc.moph.go.th/Download/vc6/slide/03_1.pdf · 2014. 10. 10. · Tetanus 0 20 40 60 80 100 0 20 40 60 80 100 1977 1981 1985 1989 1993 1997 2001](https://reader033.vdocuments.net/reader033/viewer/2022053118/609c9e7184f30260f35bab62/html5/thumbnails/17.jpg)
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
1990’s - meetings & workshops on national mechanism for vaccine policy and capacity
NVC appointed by Cabinet , NVC secretary office in DDC/MOPH
2005 Government approved national vaccine strategic plan proposed by NVC/MOPH
2011 - NVI in DDC
2012 - NVI as PSO
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มุมมอง / ภาพรวม• Gaps in vaccine security• Past records of successes• Potential capacities in
multi-sector partners • Huge enthusiasms for
development and cooperation • Ongoing efforts• Challenges
• Policy coordination & support• Human resource development• Trust & team work • Regional competition &
cooperation
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