the power of innovation. for better sterilization. autoclaves ......systec v-40 systec v-55 systec...

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the autoclave company The Power of Innovation. For better Sterilization. Autoclaves: Systec V-Series

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Page 1: The Power of Innovation. For better Sterilization. Autoclaves ......Systec V-40 Systec V-55 Systec V-65 Systec V-75 Systec V-Series: Vertical autoclaves. These autoclaves don't just

t h e a u t o c l a v e c o m p a n y

The Power of Innovation. For better Sterilization.Autoclaves: Systec V-Series

Page 2: The Power of Innovation. For better Sterilization. Autoclaves ......Systec V-40 Systec V-55 Systec V-65 Systec V-75 Systec V-Series: Vertical autoclaves. These autoclaves don't just

Systec V-40 Systec V-65Systec V-55 Systec V-75

Systec V-Series: Vertical autoclaves.

These autoclaves don't just seem to be different; they are different. Exclusively developed for special sterilization applications in thelaboratory, processes become easier, safer, more precise, more reproducible and validatable.

autoclaves_Systec_V-Seriespage_2

Space advantage!

We have created a new class of autoclavewith these new dimensions: as before, com-pact and space-saving but with increasedchamber height. Advantage: optimal loadingcapacity with most standard media andErlenmeyer flasks. Up to 50 % more loadingcapacity.

Dimensions and performance

Systec V-40 V-55 V-65 V-75 V-95 V-100 V-120 V-150

Chamber dimensions Ø x depth in mm 344 x 450 344 x 600 400 x 500 400 x 600 400 x 750 500 x 500 500 x 600 500 x 750Chamber volumein liters total / nominal 45 / 40 60 / 55 70 / 65 80 / 75 100 / 95 110 / 100 130 / 120 160 / 150External dimensionsW 500 500 550 550 550 650 650 650H 920 920 960 960 1080 985 985 1110D 740 740 780 780 780 900 900 900Heating power kW 3,6 3,6 9,0 9,0 9,0 9,0 9,0 9,0

Electrical connections for Systec V-40 and V-55: 220 – 240 V AC, 50/60 Hz, 16 A Electrical connections for Systec V-65 – V-150: 380 – 400 V, 50/6 Hz, 380 – 400 V, 50/60 Hz, 3-phase to neutral, 16 AOther voltages and single-phase operation available on request

Page 3: The Power of Innovation. For better Sterilization. Autoclaves ......Systec V-40 Systec V-55 Systec V-65 Systec V-75 Systec V-Series: Vertical autoclaves. These autoclaves don't just

Systec V-100 Systec V-120

A new dimension in technology and design.

Systec V-95 Systec V-150

Erlenmeyer flasks

Systec V-40 V-55 V-65 V-75 V-95 V-100 V-120 V-150250 ml 3 x 11 4 x 11 3 x 14 4 x 14 5 x 14 3 x 22 4 x 22 5 x 22500 ml 2 x 7 3 x 7 2 x 8 3 x 8 4 x 8 2 x 14 3 x 14 4 x 14

1000 ml 2 x 4 2 x 4 2 x 5 2 x 5 3 x 5 2 x 8 2 x 8 3 x 82000 ml 3 2 x 3 4 2 x 4 2 x 4 6 2 x 6 2 x 63000 ml 1 1 2 2 2 x 2 4 4 2 x 45000 ml 1 1 1 1 2 x 1 3 3 2 x 3

Loading capacity*

Schott–Duran media flasks

Loading capacity*

Systec V-40 V-55 V-65 V-75 V-95 V-100 V-120 V-150250 ml 3 x 17 4 x 17 3 x 20 3 x 20 5 x 20 3 x 30 3 x 30 5 x 30500 ml 2 x 11 3 x 11 2 x 15 3 x 15 4 x 15 2 x 22 3 x 22 4 x 22

1000 ml 8 2 x 8 2 x 9 2 x 9 3 x 9 2 x 15 2 x 15 3 x 152000 ml 4 2 x 4 5 2 x 5 2 x 5 8 2 x 8 2 x 85000 ml 1 1 2 2 2 x 2 4 4 2 x 410000 ml 1 1 1 1 1 2 2 2

*At max. loading, partially without baskets

autoclaves_Systec_V-Series page_3

Page 4: The Power of Innovation. For better Sterilization. Autoclaves ......Systec V-40 Systec V-55 Systec V-65 Systec V-75 Systec V-Series: Vertical autoclaves. These autoclaves don't just

Autoclaves Systec V-series:Performance categories of the 3 series types.

Vertical top-loading autoclaves Systec V-series type

From the sterilization chamber separated steamgenerator integrated into the housing xExtension of temperature and pressure to 150 °C / 5bar(only for sizes Systec V-65 — V-150) O ONumber of sterilization programs 25 12 3Password secured access rights for parameterizationand for further security relevant interventions x xPre-programmable automatic door openingat the end of a program x xAdditional PT-100 temperature sensor in the condense exhaust xRapid cooling O OPre- and post-vacuum OAir exhaust filtration O ODrying ‘Superdry’ (only in conjunction with an optional vacuum system) ORS 232 and RS 485 for external data transfer(network-compatible) x xPC-Software for extensive documentation (network-compatible) O OInternal memory for documentation ofup to 500 sterilization cycles x xIIntegrated SD-Card-Slot inclusive SD-Card (1024 MB) for data backup of up to 10.000 sterilization cycles and for transmission of process data to a PC via SD-Card reader O Otart by clock, Timer for programmable start time x xSteam exhaust condensation, water cooled, thermostatic controlled x x“Autofill“ - Automatic de-mineralized water feed for steam generation x xSpecial program for waste sterilization with pulsed heat-up for more effecient air exhaust x x xTemperature holding function after the end of program for liquids x xSpecial program for Durham-Tubes x xHousing and basic frame construction out of corrosion resistant stainless steel x x xPrepared for subsequent rapid cooling installation x xPrepared for subsequent installation of vacuum system xPrepared for subsequent drying installation xCalculation of FO value x x

Further options / Special programs (on request)Special accessories like baskets and inserts, lifting devices and wheels, available on request.

X = Standard O = Optional

VX VE VB

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Page 5: The Power of Innovation. For better Sterilization. Autoclaves ......Systec V-40 Systec V-55 Systec V-65 Systec V-75 Systec V-Series: Vertical autoclaves. These autoclaves don't just

Autoclaves Systec V-series:Three types with different performance categories.

Systec VX

For all laboratory applications even forsophisticated state-of-the-art sterilizationprocesses. With all possibilities to addadditional options for process optimizationto enable validatable sterilization to becarried out.

Systec VE

For basic laboratory applications and mediasterilization. With limited possibilities toadd additional options for process optimi-zation.

Systec VB

For simple process applications. Nooptions available for process optimization.

VX VE VB

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Page 6: The Power of Innovation. For better Sterilization. Autoclaves ......Systec V-40 Systec V-55 Systec V-65 Systec V-75 Systec V-Series: Vertical autoclaves. These autoclaves don't just

Pressure-safe upto 5 bar/150 °C.

Tomorrow's requirements are catered for intoday's design! The Systec V-Series auto-claves are the first of its kind to be designedfor higher pressures and temperatures. Thestandard pressure chamber is designed tocope with 5 bar/150 °C. If the expandedpressure and temperature model is selectedas an option, all control and safety com-ponents are adapted to the higher tem-perature and pressure. This option may befitted retrospectively.

Systec V-Series autoclaves are equippedex-factory for sterilization temperaturesup to 140 °C and a pressure of 4 bar.

The extension of pressure and temperatureto 5 bar / 150 °C is not available for SystecV-40 and Systec V-55.

autoclaves_Systec_V-Seriespage_6

Advanced technology, design and electronic intelligence!

Systec V-Series autoclaves are completelynew designs: innovative mechanical and electronic components are incorporated andguarantee high sterilization quality in thelaboratory. They thus fulfill those require-ments that will ultimately be demanded ofall laboratory sterilization processes infuture, e.g. higher sterilization temperaturesfor work with prions.

Schematic illustration of the new door-locking system of the Systec V-65 –V-150.

Lid open, circumferential locking ring in theready position.

Lid closed, circumferential locking ring in lock position. The internal steam pressure presses the lip seal between lidand chamber.

VX VEAutomaticdoor-opening.

In types VX and VE, the autoclave doorfunctions automatically – either by pres-sing a button or automatically at the endof a program. A simple system but usefulin practice. Residual steam is exhaustedautomatically without having to interruptthe process. Residual heat is used to drythe items being sterilized during the finalshort stage in the autoclave. Automaticdoor-opening is restricted to approx. 15°to avoid possible contamination from theoutside. This is especially important andfacilitates the working process whenitems to be sterilized have to remain inthe autoclave for cooling and drying. Sub-sequently, for removing the sterilizeditems, the door can be completely openedmanually.

VX VE Novel automatic lid-openingsystem.

Easy but safe – on closing, the lid is auto-matically locked by a circumferential ringsystem. A special lip seal made of heat-resistant silicone provides reliable tightness;the more the steam pressure increases, thetighter the seal becomes – without theneed for additional compressed air or othermedia!

The door-locking system is temperaturedependent – according to national andinternational standards. Also, the doorremains locked as long as there is excesspressure in the chamber. The lid, like otherparts of the pressure vessel and housing,is made of stainless steel. The attractivefaceplate of the lid, which also containsthe control panel, display and part of thecontrol technology, is made of heat-resistant and insulated plastic. There isthus no risk of the operator coming intocontact with hot components of thesystem.

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autoclaves_Systec_V-Series page_7

Immediate documentation

Optional, with integrated printer for pro-gram type, batch number, date, time, tem-perature, pressure and sterilization phase.

Menu-presented instructionsin text form!

These can be selected from German,English, French, Spanish and Italian. Otherlanguages are available as options. Large,easy-to-read display. Membrane keyboardwith acoustic confirmation signal. Ergono-mically located – everything is logical andeasy to operate.

Documentation,dialog and diag-nosis via PC.

Includes a standard RS 232 and RS 485interface for direct connection to a PC.Special software for use with Windowsoptional. Suitable for documentation of allprocess data including relevant diagrams.In addition, dialog for adapting programs,changing parameters, calibrating andadjusting. Distant diagnosis via modem isalso possible.

Available programs*

1-3 Solids4-5 Waste bags6 Liquid waste with regulated steam

exhaust for cooling7 Liquid waste for self-cooling8-10 Liquids with regulated steam

exhaust for cooling11 Liquids for self-cooling12 Cleaning13 Vacuum test**14 Bowie-Dick Test**15-25 Free for individual programming

**Only in combination with a vacuum device

Available programs*

1-3 Solids4-5 Waste bags6 Liquid waste with regulated steam

exhaust for cooling7 Liquid waste for self-cooling8-10 Liquids with regulated steam

exhaust for cooling11 Liquids for self-cooling12 Cleaning

Available programs*

1 Solids2 Waste bags3 Liquid waste with regulated steam

exhaust for cooling

* All programs can be individually parametered

VX VE

VX VE VB

New generation – with microprocessor and software!

Pressure and temperature regulation is viaan electronic pressure sensor in the steri-lization chamber or a flexible temperaturesensor in a reference vessel (for liquids). A microprocessor specially developed forour autoclaves regulates and controls allrelevant systems. In addition to vaporpressure, temperature and sterilizationtime all options such as rapid cooling, pre-and post-vacuums and drying are included.

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SteamGenerator

Design – pure innovation!

autoclaves_Systec_V-Seriespage_8

Condensationinstead of steamremoval!

Exhaust steam is condensed automaticallyvia a PT 100-regulated cooling system.This prevents odors and protects wastewater piping that may be made of plastic.

Steam generation Steam generation

VX VE VB

VX VESteam generation!

A separate steam generator is incorporatedin the housing. This has substantial advantages:

– No heating elements and no reservoirfor dirty water in the chamber

– In conjunction with the stand-by pre-heating option, only 10 min. heatingtime to 121 °C with an empty chamber

– Improved removal of air from the emptychamber via pulsed heating (rapidattainment of optimal steam atmosphere)

– Accuracy better than ± 0.3 K with emptychamber

– Quicker cooling as neither hot water in the chamber nor the separate steamgenerator need be cooled

– On cooling, steam is immediately available for the next sterilization run

VX Conventionalsteam generation.

In this system, powerful heating elementsare integrated directly on the floor of thesterilization chamber. As required, deionizedwater can be fed in, heated and convertedto steam. The deionisized water for steamgeneration can be fed in manually, and forVE-series also automatically with demine-ralised water connection.

VE VB

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autoclaves_Systec_V-Series page_9

High, all-round quality!

The pressure vessel is made of corrosion-resistant electro-polished stainless steel1.4571 (V4A) AISI 316 Ti and is thus easyto clean. The excess pressure release safetyvalve is of the approved component type.Autoclave framework and housing are also

Compressed air connection (optional)Demineralized water feed for steam generationCooling water feedCollection outlet (drain)

RS 232/485 interfaceFlexible power connection with CEE plug

made of stainless steel. The highly efficient,high-quality Hanno-Tect insulation mate-rial releases no particles; thus, the SystecV-Series can be used under clean roomconditions.

Guaranteed sterilization ofliquids!

During the entire sterilization process thetemperature is measured by a PT 100 flexible temperature sensor in a referencevessel. In this way it is guaranteed thatthe sterilization process begins only whenthe sterilization temperature of the liquidhas been attained. The cooling temperatureis also continuously monitored. As requiredby the operating standards and to preventdelayed boiling, the door can only be opened when the temperature of the liquidhas cooled to at least 80 °C.

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autoclaves_Systec_V-Seriespage_10

Intelligent process engineering for quicker and safer processes!

The actual sterilization time of e. g. 15 – 20 minutes at 121°C is only a fraction of the total time required for the entire sterilization process. Especially when sterilizing liquids, the heating up and cooling down times are far longer (fig. 1).

tCH S

100°C1 bar

121°C2,1 bar

80 °C

°C/bar

= 10 min

fig. 1*The conventional process.

In conventional systems, the set steriliza-tion temperature may in fact be reachedwithin the autoclave; however, the liquidsto be sterilized may only have reachedapprox. 100°C. The temperature equilibriumtime between chamber and liquid temper-ature is usually much longer.

The cooling process for liquids is also veryslow as the heat under 100 °C can only bedispersed by convection via the chamberinsulation if there is no rapid cooling faci-lity.

H = Heating up phase S = Sterilization phaseC = Cooling down phase

TemperaturePressure

* The times indicated in the diagram are dependent on the size and number of items tobe sterilized.

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autoclaves_Systec_V-Series page_11

Up to 50 % shorter heat-uptimes possible as standard!

Due to the combined temperature andpressure regulation, the chamber pressureis increased during the heat-up phase. Theresult: more rapid temperature equilibriumin the liquids and a shorter heat-up time.

New system and process technology have made it possible to shorten the entire process considerably. Several hours can be saved in this way! In addition, the media need not be exposed to temperatures unnecessarily (fig. 2).

tKA S

100°C1 bar

121°C2,1 bar

80 °C

°C/bar

= 10 min

fig. 2*

Time saving through new process technology.

H = Heating up phase S = Sterilization phaseC = Cooling down phase

TemperaturePressure

* The times indicated in the diagram are dependent on the size and number of items tobe sterilized.

Up to 90 %shorter coolingtimes!

Various optional rapid cooling systemsenable the cooling times for liquids to be significantly reduced. This conservesnutrient media and makes for efficientutilization of the autoclave.

VX VE

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SteamGenerator

autoclaves_Systec_V-Seriespage_12

Radial ventilator

Together with the optional cooling system,the ventilator ensures accelerated removalof heat, through air circulation, from thesterilization load to the cooled mantle. The fan is located in the convex lid abovethe chamber (hence no reduction of cham-ber height!) and is driven via a magneticclutch by a motor fitted under the lid cover.

Exhaust air filtra-tion and steriliza-tion of condensate

When working with infectious material, theexhaust air is filtered via an autoclavablesterile filter comprising a filter cartridge withPTFE membrane, pore size 0.2 µm, incorpo-rated in a pressure-resistant housing andeasily replaced. The filter is automaticallysterilized during each sterilization process,monitored by a PT 100 temperature sensor.The condensate is retained during the heat-ing and sterilization phases and thus alsosterilized. In this way, neither aerosole particles nor microorganisms can escapebefore the sterilization process is completed.

Magnetic stirrer

For the homogeneous mixing of liquidsduring the sterilization processes. Can beplaced directly in the chamber as requiredand is provided with power via a flexiblecable through the validation port.

For the efficient drying of solids, hollowitems and porous items such as filters andtextiles. In this case, the series-installedsteam generator supplies the heat for drying. Rapid surface drying with open lidor penetrating vacuum drying in combina-tion with the optional vacuum facility arepossible. Subsequent drying in a separatedrying cabinet is thus unnecessary!

VX VE

VX

Options: prepared for special applications!

Vacuum facility

When working with infectious material, theexhaust air is filtered via an autoclavablesterile filter comprising a filter cartridge withPTFE membrane, pore size 0.2 µm, incorpo-rated in a pressure-resistant housing andeasily replaced. The filter is automaticallysterilized during each sterilization process,monitored by a PT 100 temperature sensor.Only thus a validatable sterilization ofporous materials, hollow items, textiles andwaste bags can be obtained, even with highcontamination.

SuperDry

VX

VX VE

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SteamGenerator

autoclaves_Systec_V-Series page_13

Optional: technology for special applications!

For the sterilization of liquids in closedvessels, plastic bottles, bags, cans, blistersor food packs, e. g.:– System and program for sterilization

in a mixture of steam and air– System and program for sterilization

with hot water spraying and spray cooling

Up to 90 % quicker cooling!

Systec autoclaves are equipped with clas-sical cooling systems (regulated steamexhaust down to 100 °C) and subsequentextremely slow self-cooling to min. 80 °C;however, optional systems for rapid coolingare available:

– Mantle cooling with cooling water– Mantle cooling with cooling water and

support pressure– Mantle cooling with cooling water

recirculated through a heat exchanger– Radial ventilator for air circulation and

accelerated heat removal in the chamber– Spray cooling with recirculated and

recooled sterile water and support pressure

– Cooling with ambient air ventilation

VX VE

The right process for your sterilization application:

+ recommended procedure ? eventually acceptable - not possible

Air release Cooling Drying Other

Gravitation Single Pulsed Fractionated Conventional Rapid cooling Surface drying Drying with Exhaust airpre-vacuum heat up pre-vacuum cooling with system without subsequent filtration

(over pressure slow steam with support vacuum vacuumApplication: pulses) release pressure +SuperDry +SuperDry

Liquids + ? - - ? + - -Unpacked non hollow items + + + + ? +Porous materials(filters, textiles) - ? ? + - +Hollow items(pipette tips,empty glassware, tubes and hoses) - - - + - +Contaminated waste in “destruction bags” - - ? + - - +

Procedure/Process:

Important notice for effective sterilization!

As already described, several options areavailable should it be necessary to obtaincorrect and validatable results or rapidcooling times, especially in the case ofliquids. The options that can be useddepend on the type of items to be sterili-zed. It is thus important for you to thinkcarefully about your requirements so thatthe autoclave can be optimally configured

for the tasks on hand. A validatable sterilization process with confirmable bio-logical efficiency can only be obtained ifthe instrument configuration has been correctly thought out. The table belowprovides help in establishing the desiredconfiguration; however, we recommendobtaining additional advice from ourexperts.

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System accessories for ease of handling!

Lifting device for heavy items!

The electrical lifting device with swiveledarm facilitates the loading and unloadingof heavy items. The arm can be operatedby a mobile control panel. The liftingdevice is firmly attached to the side of theautoclave. The swivel arm has a specialgrip for baskets; they thus remain stableeven when full.

autoclaves_Systec_V-Seriespage_14

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Each and every component used is subjectedto stringent controls and each autoclaveis thoroughly checked for function beforebeing delivered. An acceptance protocol isissued.

Step-by-step documentationoptionally available!

Our Quality Management fulfills the high-est requirements with regard to testingand documentation. Within the scope ofour service, we also provide qualificationand validation work with GMP-compliantdocumentation, e. g.: – DQ Design Qualification– IQ Installation Qualification– OQ Operation Qualification– PQ Performance Qualification

Our Quality Assurance

autoclaves_Systec_V-Series page_15

Wire mesh baskets out of stainless steel, stackableInner Dimensions

Art. No ø x h (mm) V-40 V-55 V-65 V-75 V-95 V-100 V-120 V-150Hold capacity per autoclave

1654 305 x 190 21655 305 x 280 1 27215 360 x 225 2 37212 360 x 280 27210 360 x 355 1 1 27225 460 x 230 2 37222 460 x 280 27220 460 x 355 1 1 2

Bucket out of stainless steel, stackable, with ventilation holes only in the upper part, bottom closed, for waste sterilizationInner Dimensions

Art. No. ø x h (mm) V-40 V-55 V-65 V-75 V-95 V-100 V-120 V-150Hold capacity per autoclave

1657 325 x 385 1 17230 350 x 355 1 1 27235 465 x 355 1 1 2

Bucket out of stainless steel, stackable, with ventilation holes only in the upper part, bottom closed, for waste sterilization with swivel lidInner Dimensions

Art. No. ø x h (mm) V-65 V-75 V-95 V-100 V-120 V-150Hold capacity per autoclave

7240 345 x 270 1 2 27245 450 x 350 1 1 2

Loading baskets and inserts

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t h e a u t o c l a v e c o m p a n y

Systec GmbH Labor-SystemtechnikSandusweg 11D-35435 WettenbergTel. +49 (0) 641-98211-0Fax +49 (0) 641-98211-21E-Mail: [email protected]: www.systec-lab.com

Performance and competence!

We only make one thing: laboratory autoclaves.But we do this exceptionally well!

Our goal is always to make laboratory worksafer, easier, more accurate and more eco-nomical. With over 25 years of experienceand constant cooperation with experts inpractice, we know how to tackle and pro-vide optimal solutions for even the mostcomplex of sterilization tasks.

We have the knowledge and know-how toproduce the results!

Our expertise and know-how are availablefor you worldwide through specializedpartners.

Product expertise:

– Development– Design– Production of series products– Production of specialty products– Application and technical advice

Additional services:

– Installation and start-up– Special technical developments– Tests and process development– Individual service on-call– Contract service – Qualification and validation– GMP-compliant documentation

Performance and competence!

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Rights reserved to change technical aspectsas required.

Subsidiary Switzerland:Systec Schweiz GmbHBösch 23CH-6331 HünenbergTel. +41 (0) 41 781 52 80Fax +41 (0) 41 781 52 79E-Mail: [email protected]: www.systec-lab.ch