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The World Center for Anti-Aging & Regenerative Medicine:

A Center of Excellence for State-of-the-Art Age Reversal

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Executive Statement Dr. Robert Goldman & Dr. Ronald Klatz

Around the world, people are seeking expert medical guidance for ways to stay healthy, active, and vital well into their older years. As a result, the principles of the anti-aging medical model have gained rapid and widespread acceptance as a framework for lifelong habits for healthy living. Anti-aging medicine is a clinical specialty is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases. The goal of anti-aging medicine is not to merely prolong the total years of an individual's life, but to ensure that those years are enjoyed in a productive and vital fashion. Regenerative medicine is a medical specialty that applies advanced biomedical technologies for the purposes of renewing body tissues with

the goal of maintaining the human body in normal-to-peak function for a prolonged period of time. Taken collectively, the advancements offered by anti-aging and regenerative medicine to improve the quality of, and/or extend the length of, the human lifespan, are the singlemost potent emerging biomedical technologies today. Anti-aging and regenerative medicine are now practiced by tens of thousands of physicians in private medical offices, as well as at some of the most prestigious teaching hospitals around the world. Universally, those involved in healthcare, or those whose fields of expertise intersect with healthcare issues, support anti-aging and regenerative medicine as

a healthcare model promoting innovative science and research to prolong the healthy human lifespan. Public policy organizations and government agencies are now embracing anti-aging/regenerative medicine as a viable solution to alleviate the mounting social, economic, and medical woes otherwise anticipated to arrive with the aging of nearly every nation on the planet. The World Center for Anti-Aging & Regenerative Medicine functions as a world-class, university affiliated research and treatment facility unique in its focus on the investigation and application of diagnostic and treatment protocols that extend the length, and enhance the quality, of the human lifespan. The World Center will unite the world’s top physicians under the umbrella of a new hospital medical resort complex, to which patients will return annually to undergo a comprehensive and personalized program of rejuvenative and restorative longevity therapies.

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The World Center serves as a positive draw for retirement communities, high-end housing, luxury hotels, and upscale real estate developments to locate within a close proximity. Residents at such properties will wish to be close to the facility in order to take full advantage of the breadth of medical services provided at The World Center. By serving as a cornerstone drawing attraction to the region, the establishment of The World Center beneficially impacts the real estate market of the host venue. The World Center for Anti-Aging & Regenerative Medicine will be the major training center for

anti-aging physicians. It will be the world’s premier research center for clinical anti-aging / regenerative medical therapeutics. As well, The World Center will aim to identify breakthrough anti-aging interventions first, thereby positioning itself to patent and/or develop proprietary technologies from its key central position in the industry. Essentially, all roads in/to anti-aging medicine, as well as its key products and services, will originate from The World Center.

The World Center for Anti-Aging & Regenerative Medicine is established as the true pinnacle of the anti-aging medical movement. The World Center fosters essential research in the anti-aging and regenerative medical sciences that will ultimately lead to universal protocols to stave off aging-related diseases and disorders. The potential now exists for 20 to 30 years of optional functioning life extension in humans, given animal studies, as well as demographic studies of long-lived human populations. The World Center for Anti-Aging & Regenerative Medicine elevates the standard of care for advanced preventive medicine to improve healthcare for all peoples of the world, and will become the Gold Standard against which all other advanced medical facilities will be measured. The World Center will serve a rich and powerful global clientele, as it is the sole medical facility to effectively offer the full complement of state-of-the-art diagnostic and treatment protocols to intervene in the diseases and disorders of aging.

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Development Phases Phase I Construction and opening of The World Center for Anti-Aging & Regenerative Medicine, a 100,000 sqft state-of-the-science clinical facility. An intensive Internet, print media, and direct mail campaign announces The World Center and highlights the brilliant foresight of the nation and its governmental officials in embracing innovation, scientific invention, and advanced technologies. This positive publicity draws the world’s brightest scientific minds to visit and train at The World Center, thereby affording the nation the opportunity to showcase its unparalleled position as a global leader in the advanced medical sciences. Within a very short time, the venue city is recognized worldwide and brings much pride and honor to the nation. Phase II A After the successful establishment of The World Center, a major financial opportunity exists in the creation of an adjacent ring of affiliated specialty treatment clinics focused on state-of-the-art treatment of the degenerative diseases of aging. Referrals to these affiliate clinics will be provided after patients receive their intensive and comprehensive physical and biochemical analyses and physician examinations provided to the elite clients of The World Center. Such specialty clinics would arise spontaneously due to the demand for the world’s best and most innovative treatments of diseases such as Alzheimer’s, neurodegenerative disorders, cancers, diabetes, and other conditions associated with the degenerative diseases of aging. Each of these centers would in and of themselves be a significant profit center and have a magnetic draw benefitting the new health tourism industry created by the attraction created by The World Center. Phase IIB

Just as the Mayo brother physicians in 1889 established The Mayo Clinic (Minnesota, USA), their success and notoriety established the seed for an entire metropolitan community focused on healthcare. Hospitals, outpatient clinics, luxury hotels, and extended-stay housing for patients and their families will create an interlinked campus. The World Center campus will offer upper-end retirement housing, as well as resort-style residence, in a radius emanating proximally from The World Center. These properties will offer the elite clientele of The World Center the ability to have direct access to The World

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Center’s contemporary facilities. Wealthy families will rotate family members to The World Center on a bi-annual basis to participate in the rejuvenative medical protocols. Those patients that may require more prolonged and intensive rehabilitation will reserve housing for an extended stay. Further, The World Center will support college and postgraduate level education, serving as the major training center for anti-aging physicians. As such, hundreds of visiting physicians and scientists who participate in the academic educational & research programs at The World Center will stay at the on-campus housing properties. In addition, The World Center campus will expand via adjunctive buildings that support the healthcare framework. For example, pharmaceutical research, food manufacturing, and private medical offices will create a network of related supporting medical and health businesses, providers, and vendors. The World Center will create a major economic opportunity in terms of commerce and construction, with high-end shopping districts and entertainment venues supplementing the core medical services provided by The World Center. This rapidly established metropolitan complex established on the backbone of medical tourism establishes not only a campus – but a community – unified by The World Center. In reality, The World Center community represents the apex of advanced preventative medical sciences – that is, anti-aging medicine.

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Authority of Endorsing Principals

Dr. Robert Goldman, M.D., Ph,D., D.O., FAASP, is physician co-founder and Chairman of the Board of the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net) and Chairman of the World Anti-Aging Academy of Medicine (www.waaam.org). Dr. Goldman serves as Chairman of the International Medical Commission overseeing sports medicine committees in over 184 nations. He also is President Emeritis of the National Academy of Sports Medicine (www.nasm.org), and founded the International Sports Hall of Fame (www.SportsHOF.org). Dr. Goldman has overseen cooperative research agreement development

programs in conjunction with such prominent institutions as the American National Red Cross, the US National Aeronautics and Space Administration (NASA), the Department of Defense, and the FDA's Center for Devices & Radiological Health. Dr. Goldman has served as a Senior Fellow at the Lincoln Filene Center, Tufts University; as an Affiliate at the Philosophy of Education Research Center, Graduate School of Education, Harvard University. He currently holds professorships at Universities in China, Indonesia, Korea, and Brazil.

Dr. Ronald Klatz, M.D., D.O. . is a physician, medical scientist, futurist, and innovator. He coined the term "anti-aging medicine" and is recognized as a leading authority in the new clinical science of anti-aging medicine. Dr. Klatz is the physician founder and President of the American Academy of Anti-Aging Medicine – A4M. Since 1981, Dr. Klatz has been integral in the pioneering exploration of new therapies for the treatment and prevention of age-related degenerative diseases. He is the inventor, developer, or administrator of 100-plus scientific patents, including those for technologies for brain resuscitation, trauma and emergency medicine, organ transplant and blood preservation. Today, Dr. Klatz helps to support aging-related biotech research and supervises postgraduate medical training

programs for physicians from 120 countries. A best-selling author and columnist, Dr. Klatz is Medical Editor for The World Health Network – the A4M’s educational website at www.worldhealth.net.

Founded by Dr. Goldman and Dr. Klatz in 1991, The American Academy of Anti-Aging Medicine (A4M, Chicago IL, www.worldhealth.net) is a not-for-profit medical society dedicated to the advancement of technology to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. A4M is also dedicated to educating physicians, scientists, and members of the public on anti-aging issues. A4M believes that the disabilities associated with normal aging are caused by physiological

dysfunction which in many cases are ameliorable to medical treatment, such that the human life span can be increased, and the quality of one's life improved as one grows chronologically older. A4M seeks to disseminate information concerning innovative science and research as well as treatment modalities designed to prolong the human life span. The A4M is comprised of 26,000 physician, scientist, and health practitioner members from 120 nations who are forging a profound healthcare paradigm shift spearheaded by research and clinical pursuits that enhance the quality, and extend the quantity, of the human lifespan.

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Market Overview

Global Anti-Aging Industry Trends The worldwide anti-aging marketplace is:[1,2]

Valued at $250 Billion (2012) Projected to grow at a compound annual growth rate of 5.7% To top $345 billion in 2018

Demographics of End-Users:

Traditionally, the anti-aging market has been driven by the aging Baby Boomer generation, who are “[d]riven by the desire to stay young and healthy,” which is anticipated to prompt “sales of dietary supplements, vitamins, and minerals … to rise in the upcoming years.”[3]

Younger consumers are now being attracted to anti-aging products and services. This expansion of the market audience is projected help drive the anti-aging industry’s growth into the future. “With younger consumers becoming more proactive about their skin maintenance regime, women aged between 25 years to 30 years are increasingly beginning to use anti-aging creams, thereby resulting in expanded market opportunities.” The anti-aging industry may see a “shift from [products] being just healthcare enhancers to beauty enhancers.” [3]

[1] ”BCC Research Publishes A New Report on Global Markets for Antiaging Products and Services,” PR Web, Sept. 17, 2013. [2] Anti-Aging Products - Executive Summary” p. II-1, in “Anti-Aging Products: A Global Strategic Business Report: MCP-1107,” Global

Industry Analysts, Inc., San Jose, CA. March 2008; “Anti-Aging Products: A Global Market Report,” Global Industry Analysts, Inc., San Jose, CA. March 2009.

[3] “World Anti-Aging Products Market to Reach US $115.5 Billion by 2010, According to New Report by Global Industry Analysts,” PRWeb, 10 March 2008.

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Unique & Customized Age Reversal Program

As we age, changes take place in our body systems. Cellular processes slow down, and our organs and tissues become less robust in performing their tasks and functions. From head to toe, and beginning as early as the second decade of life, our body systems begin to demonstrate senescence signs of old age. An understanding of these age-related declines enables us to better grasp the potential for contemporary medical discoveries and applications of biomedical technology to retard or reverse the otherwise inevitable process of senescence. In other words, we will, in this series of articles, obtain an idea of just how we age if we choose to sit back and do nothing about it, if we let the process of aging engulf and, ultimately, end our lives long before necessary. The ten key systems in the body that age are:

1. Endocrine system, responsible for the hormonal response 2. Immune system, which mounts the body's response to infectious invaders 3. Metabolic system, involving age-related physiology changes 4. Cardiovascular system, involving the heart and arteries 5. Gastrointestinal system, affecting absorption of nutrients from food 6. Reproductive system, including menopause (in women) and andropause (in men) 7. Nervous system, responsible for the body's muscular response to stimuli 8. Brain function, including memory and cognition 9. Muscular system, involving strength and function 10. Sensory system, including the senses of touch, taste, smell, sight, and hearing

While until now the declining performance in these biological processes has been accepted as a "natural" part of aging, in the anti-aging medical model we no longer consider the declines as inevitable. Anti-aging medicine addresses aging as a treatable medical condition, aiming to reduce or eliminate the disabilities, diseases, and dysfunctions we have grown used to assuming are a part of growing older. Drawing upon the latest medical breakthroughs across specialties of medical science, The World Center is renowned for its delivery of cutting-edge, high-technology methods that revolutionize the diagnostic measurement of the aging process. The World Center deploys the anti-aging medical model of a multi-disciplinary approach towards advanced preventative medical care. To accomplish its age regression goals, The World Center offers a diverse array of innovative medical therapeutics, a decade in-advance of what is provided at today’s existing elite medical centers such as Mayo Clinic or Harvard University affiliated Hospitals. These breakthrough biomedical technologies

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include: replacement joints, artificial organs, platelet rich plasma rejuvenation therapy, multi growth factor augmentation, intravenous therapy, bone marrow banking, stem cell therapies, and more. Diagnostic Assessments Biomarkers of Aging

Laboratory Markers:

Mitochondrial energy production Bone density Production of intrinsic intracellular antioxidant molecules (demonstrating antioxidant protection/buffering capacity)

Thyroid function

Collagen crosslinking histology Cortisol Liver enzymes IGF-1 HbA1C / 3 hr GTT + insulin curve Testosterone, estrogen, progesterone Albumin / Total protein DHEA Kidney function Melatonin

Physical Markers:

Body composition and body fat Grip strength Bone density – ultrasound, atomic absorption Memory EKG and R1-R2 variability Psychological disposition Peripheral vascular circulation Nerve conduction velocity evoked response Cardiac output Bowel function & transit time Pulmonary function Central nervous system processing speed,

including brain (P300) Peripheral pulse pressures Sensory function: including olfactory, taste,

hearing, tactile, and visual accommodation Kidney filtration/renal function Balance and coordination Spinal anatomy and flexibility Reaction time

Advanced Diagnostic Biomarkers:

Infrared, Ultrasound, and MRI imaging – noninvasive “head to toe” examinations

Computerized cognitive analysis – to identify signs of declines in memory and cognition

Genomic testing – to assess risk factors of future disease Microscopy – to discern blood-based disorders Sleep lab – to reveal underlying disease contributors such as apnea Dental examination – to assess potential infectious pathogens

invading the body

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Therapeutic Interventions To accomplish its age regression goals, The World Center will offer a diverse array of innovative medical therapeutics, a decade in-advance of what is provided at today’s existing elite medical centers such as Mayo Clinic or Harvard University affiliated Hospitals. These breakthrough biomedical technologies include:

• Replacement joints • Artificial organs • Brain / neurological implants • Vision / hearing enhancement devices • Platelet rich plasma rejuvenation therapy • Multi growth factor augmentation • Sleep therapy • Blood plasmaphoresis • Genetic engineering • Intravenous therapy • Phototherapy • Bone marrow banking • Stem cell therapies for age regression

c

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Proformas Estimated Expenditures

Project funding is estimated at US $50 Million.

NUMBER EACH LINE TOTAL

STAFFING REQUIREMENTS (compensation inclusive of salaries, benefits, bonuses, and perks)

Medical Director 1 200,000 200,000Assistant Medical Director 1 165,000 165,000General Manager 1 125,000 125,000Clincal Care Team: Program Administrator 2 110,000 220,000Staff Physician 6 200,000 1,200,000Medical (Life Extension) Technician 4 60,000 240,000Sports Physiologist/Physical Trainer 2 75,000 150,000Physical Therapist Assistant 3 50,000 150,000Staff Psychologist / Counselor 1 70,000 70,000Laboratory Technicians 2 55,000 110,000Pharmacist / Dispensary Manager 1 100,000 100,000Pharmacy Technician 2 50,000 100,000Patient Care Coordinator (RN level) 4 80,000 320,000Research Team: Research Director 1 150,000 150,000Research Doctorates 6 80,000 480,000Research Assistants 4 50,000 200,000Medical Librarian 1 60,000 60,000Support Team: Receptionist/ Office Clerk 4 45,000 180,000Bookkeeper/Collection 2 50,000 100,000IT Manager 1 75,000 75,000Computer Technician 1 50,000 50,000Public Relations/Media Spokesperson 1 100,000 100,000Total Staffing Costs, Estimated 4,545,000Staffing Costs, Years 2-5 18,180,000

DIAGNOSTIC EQUIPMENT Cell biology / tissue regeneration lab 2 675,000 1,350,000Spiral CT Scanner Diagnostic Imaging 1 900,000 900,000SPECT Scanner Diagnostic Imaging 1 750,000 750,000Diagnostic Ultrasound Scanner 2 150,000 300,000Ultrasound with Plethisonography 2 70,000 140,000Ultraviolet Face and Body Photography 4 25,000 100,000Basal Metabolic Rate Cart CO2/O2 Analyzer 2 50,000 100,000IR Thermagraphy / Tetrahertz Camera 2 55,000 110,000Retinal Camera Microscope 2 50,000 100,000Dermal and Scalp Microscope 2 40,000 80,000Darkfield High Power Microscope and TV Display

2 35,000 70,000

Digital Fluroscope Xray Suite / Procedure room

1 350,000 350,000

Dynomometer, Back and Spine (Medx) 1 150,000 150,000

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QEEG (P-300) 1 65,000 65,000HBO Tx Station 4 120,000 480,000Clinical Laboratory Equipment (microscopes, automated blood lab, etc)

1 500,000 500,000

Medical Disposibles 1 250,000 250,000Miscelleneous Medical Supplies (reagents etc)

1 150,000 150,000

Total Diagnostic Equipment, Estimated 5,945,000Diagnostic Consumables, Years 2-5 1,600,000

THERAPEUTIC EQUIPMENT Physical Therapy Treatment Area (traction, therapeutic massage, lymphatic drainage, electrotherapeutics, showers) & Buildout

1 550,000 550,000

Physical Therapy Procedure Rooms 4 35,000 140,000Therapeutic / Muscuskeletal Rehab Pools 2 100,000 200,000Sauna / Spa facility (hot pool immersion bath, IR / dry sauna) & Buildout

1 1,000,000 1,000,000

Evoked Response / Brain EEG Analysis & Training

2 50,000 100,000

Aesthetics Suite & Buildout 4 75,000 300,000Aesthetics Suite Equipment (2/each @ dermal laser, fractal, intensed pulsed light, CO2, rubium, plasma)

2 510,000 1,020,000

Aesthetics Supplies & Disposibles 1 120,000 120,000Compounding Pharmacy & Buildout (incl equipment - incl fulfillment)

1 1,000,000 1,000,000

Compounding Pharmacy Supplies & Pharmaceuticals

1 350,000 350,000

Total Therapeutic Equipment, Estimated 4,780,000Therapeutic Consumables, Years 2-5 1,880,000

FIXED OVERHEAD ITEMS Rent (75,000 sf, $20/ft) 1 $1,500,000 $1,500,000Legal and accounting 1 $350,000 $350,000Insurance (incl E&O) 1 $125,000 $125,000Exam/consult room furnishings & decorating 20 $10,000 $200,000Office furnishings, computers (networked) 25 $15,000 $375,000Telemedicine Room furnishings (AV) & Buildout

2 $80,000 $160,000

Marketing - videos, in-office literature, website etc

1 $175,000 $175,000

Mail (including direct mail campaigns) 1 $225,000 $225,000Telephone 1 $100,000 $100,000Fixed Overhead, Estimated -- Year 1 $3,210,000Fixed Overhead, Estimated -- Years 2 -5 $9,900,000

GRAND TOTAL, WORLD CENTER, YEAR 1 OPERATING COSTS 18,480,000GRAND TOTAL, WORLD CENTER, YEARS 2-5 OPERATING COSTS 31,560,000GRAND TOTAL, WORLD CENTER, YEARS 1-5 OPERATING COSTS 50,040,000

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Potential / Projected Revenues

LEVEL ELEMENTS PRICING % OF CONSULTS/YEAR

I Basic LExScan (heart/lungs/abdominal) 499 30% Radiology consult (videotape--selected images, short report) II Total LExScan (heart/lungs/abdominal/brain/spine) 699 10% Intake/H&P via patient-administered software Anti-aging projections Radiology consult (10-min Q&A live)

III Total LExScan (heart/lungs/abdominal/brain/spine) 999 40% Intake/H&P via patient-administered software Anthropometric Assessment LExChemistries Specimen Testing Radiology consult--extended (20 minutes live) Nutritional consultation (certified nutritionist, 30 minutes)

IV Executive Health Program 1399 20% equals Level III plus: expanded anthro assmt & lab testing derm evals cognitive assessment

BASE CONSULT ADD-ON CLIENTS ($11,650/yr/pt) LEVEL CONSULT $ PER 10 CLIENTS % OF SCAN CLIENTS ADD-ON $ I 499 3 0 0II 699 1 0 0III 999 4 0.25 2875IV 1399 2 0.5 5750

ADD-ONS: Expanded wellness lab tests = $2,000/yr Derm evals = $250/yr Derm treatments = $600/yr Derm products = $800/yr HRT = $6,000/yr Nutraceuticals = $2,000/yr Total add-on $/pt = $11,650/yr

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(Per 10

clients=3/1/4/2 Breakdown)

(Per 10 clients=0/0/0.25/0.5 Brkdn)

MONTH NUMBER PATIENTS ENROLLED*

MONTHLY REVENUE: BASE CONSULT

MONTHLY REVENUE: ADD-ONS

MONTHLY REVENUE--SUBTOTAL

FACILITY'S RUNNING GROSS REVENUE TOTAL

0-6 0 $0 $0 $0 $07 5 $4,495 $11,650 $16,145 $16,1458 10 $8,990 $23,300 $32,290 $48,4359 30 $26,970 $69,900 $96,870 $145,30510 60 $53,940 $139,800 $193,740 $339,04511 80 $71,920 $186,400 $258,320 $597,36512 100 $89,900 $233,000 $322,900 $920,26513 120 $107,880 $279,600 $387,480 $1,307,74514 140 $125,860 $326,200 $452,060 $1,759,80515 160 $143,840 $372,800 $516,640 $2,276,44516 180 $161,820 $419,400 $581,220 $2,857,66517 200 $179,800 $466,000 $645,800 $3,503,46518 220 $197,780 $512,600 $710,380 $4,213,84519 240 $215,760 $559,200 $774,960 $4,988,80520 260 $233,740 $605,800 $839,540 $5,828,34521 280 $251,720 $652,400 $904,120 $6,732,46522 300 $269,700 $699,000 $968,700 $7,701,16523 320 $287,680 $745,600 $1,033,280 $8,734,44524 340 $305,660 $792,200 $1,097,860 $9,832,30525 360 $323,640 $838,800 $1,162,440 $10,994,74526 380 $341,620 $885,400 $1,227,020 $12,221,76527 400 $359,600 $932,000 $1,291,600 $13,513,36528 410 $368,590 $955,300 $1,323,890 $14,837,25529 420 $377,580 $978,600 $1,356,180 $16,193,43530 430 $386,570 $1,001,900 $1,388,470 $17,581,90531 440 $395,560 $1,025,200 $1,420,760 $19,002,66532 450 $404,550 $1,048,500 $1,453,050 $20,439,57033 460 $413,540 $1,071,800 $1,485,340 $21,892,62034 470 $422,530 $1,095,100 $1,517,630 $23,313,38035 480 $431,520 $1,118,400 $1,549,920 $24,669,56036 500 $449,500 $1,165,000 $1,614,500 $26,025,74037 515 $462,985 $1,199,950 $1,662,935 $27,365,77538 530 $476,470 $1,234,900 $1,711,370 $28,689,66539 545 $489,955 $1,269,850 $1,759,805 $29,997,41040 560 $503,440 $1,304,800 $1,808,240 $31,289,01041 575 $516,925 $1,339,750 $1,856,675 $32,564,46542 590 $530,410 $1,374,700 $1,905,110 $33,823,77543 605 $543,895 $1,409,650 $1,953,545 $35,066,94044 620 $557,380 $1,444,600 $2,001,980 $36,293,96045 635 $570,865 $1,479,550 $2,050,415 $37,504,83546 650 $584,350 $1,514,500 $2,098,850 $38,699,56547 665 $597,835 $1,549,450 $2,147,285 $39,878,15048 680 $611,320 $1,584,400 $2,195,720 $41,040,59049 690 $620,310 $1,607,700 $2,228,010 $42,170,74050 700 $629,300 $1,631,000 $2,260,300 $43,268,60051 710 $638,290 $1,654,300 $2,292,590 $44,334,170

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52 720 $647,280 $1,677,600 $2,324,880 $45,367,45053 730 $656,270 $1,700,900 $2,357,170 $46,400,73054 740 $665,260 $1,724,200 $2,389,460 $47,434,01055 750 $674,250 $1,747,500 $2,421,750 $48,467,29056 760 $683,240 $1,770,800 $2,454,040 $49,500,57057 770 $692,230 $1,794,100 $2,486,330 $50,533,85058 780 $701,220 $1,817,400 $2,518,620 $51,567,13059 790 $710,210 $1,840,700 $2,550,910 $52,600,41060 800 $719,200 $1,864,000 $2,583,200 $53,633,690

*Conservative estimates on growth of patient base: fast growth in months 12-24; slower growth in months 37-60.

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Concluding Remarks

A prolonged healthy lifespan – and the practice of the anti-aging medical specialty – beneficially impacts the economic framework of nations around the world. Until we've eradicated the age-related decline in health that leads to many of us becoming dependent and disabled in our older years, society will bear increasing financial costs to sustain the older population. In the absence of scientific solutions that halt the onset of the degenerative diseases of aging, the elderly support

burden may swell and compromise the economic and social frameworks of many industrial nations. In that anti-aging medicine is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans, the field’s most important contribution will be in the reduction of disabilities, diseases, and dependencies otherwise associated with aging and greying populations. To achieve this legacy goal, The World Center for Anti-Aging & Regenerative Medicine unites the world’s top physicians under the umbrella of a new hospital medical resort complex, serving as a highly evolved conceptualization of a Medical Tourism destination that is unique and unparalleled in medical excellence.

\

American Academy of Anti-Aging Medicine | 1510 West Montana Street | Chicago, IL 60614 USATel: 773-528-6100 | Fax: 773-929-5733

Internet: www.worldhealth.net | www.a4m.com

Established 199126,000+ physician & scientific members120 countries

The GlobalAnti-Aging Market

THE GLOBALANTI-AGINGMARKETPLACE-- Stood at ZERO dollars

prior to 1991 (the year A4M was established)

-- Valued at $250 billion in 2012

-- Projected to grow at a compound annual growth rate of 5.7%

-- To top $345 billion in 2018

”BCC Research Publishes A New Reporton Global Markets for Antiaging

Products and Services,” PR Web, Sept. 17, 2013

With a total validated circulation of

17 million readers/visitors,

Dr. Ronald Klatz & Dr. Robert Goldmancreated the space of anti-aging medicine.

Dr. Ronald Klatz & Dr. Robert Goldman co-founded the sector’s leading professional organization, The American Academy of Anti-Aging Medicine (A4M), a federally registered non-profit medical society dedicated to the advancement of technologyto detect, prevent, and treat aging related disease and to promoteresearch into methods to retard and optimize the human aging process.A4M is also dedicated to educating physicians, scientists, and members of the public on biomedical sciences, breaking technologies,and anti-aging issues.

The vast majority of anti-aging physicians are board certified in a primary medical specialty that is recognized by the AMA establishment.

Medical PioneersDr. Robert Goldman, M.D., Ph,D., D.O., FAASP, is physician co-founder and Chairman of the Board of the American Academy of Anti-AgingMedicine (A4M) and Chairman of the World Anti-Aging Academy of Medicine. He has served as a Senior Fellow at the Lincoln Filene Center, Tufts University; as an Affiliate at the Philosophy of Education Research Center, Graduate Schoolof Education, Harvard University. Dr. Goldman currently holds professorships atUniversities in China, Indonesia, Korea, and Brazil.

Dr. Goldman serves as Chairman of the International Medical Commissionoverseeing sports medicine committees in over 184 nations. Dr. Goldmanserved as Special Adviser & Lecturer to the US Drug Enforcement Agency (DEA)

Demand Reduction Education Programs nationally, as well as to the US Olympic Committee, spearheadingthe design of drug policy and testing procedures.

Dr. Goldman is author of Death In the Locker Room (1984), a first-ever expose of the illicit use of anabolic steroids in sports, that remains widely regarded as the seminal text on the dangers of anabolicand performance enhancing substances in sports. Death in the Locker Room was the first book to alert the public and the medical community to such issues, and the book subsequently led directly to much ofthe drug testing, control, and educational programs now in-place across a number of professional sportsand on the global level.

Dr. Goldman is the cofounder and presently serves as President Emeritis of the National Academy ofSports Medicine (NASM) , the global leader in certification, continuing education, solutions and tools for the health, fitness, sports performance and sports medicine professionals.

In 2012, Dr. Goldman founded the International Sports Hall of Fame, a non-profit foundationestablished to honor the world’s greatest athlete legends in all sports.

A world champion athlete with over 20 world strength records, Dr. Goldman has been listed inthe Guinness Book of World Records. Some of his past performance records include 13,500consecutive situps and 321 consecutive handstand pushups.

Dr. Goldman is the 2013 recipient of the Dwight David Eisenhower Fitness Award, bestowed for outstanding individual or cumulative achievement in fitness and contributions to the growth and development of sport fitness through outstanding leadership activity. A black belt in karate and Chinese weapons expert, in 2012 he was inducted into the MartialArts Hall of Fame. Dr. Goldman received the 2014 Honor Award Martial Arts History Museum,and the title of Honorary Grand Master Black Belt Certificate in Martial Arts Shim Shin Do.

www.sportsHOF.org

Dr. Robert Goldman & Dr. Ronald Klatz found theNational Academy of Sports

Medicine (NASM), whichcreated the specialty ofpersonal sports trainersin sports medicine

1985 1991

Dr. Robert Goldman & Dr. Ronald Klatz found theAmerican Academy of Anti-Aging Medicine (A4M).They envision anti-aging medicine as a direct extension

of sports medicine. Just as sports medicineaims to keep the athlete’s body functioning atits optimum level, anti-aging medicine seeksto keep the body functioning at its peak.

1994

Dr. Robert Goldman &Dr. Ronald Klatz foundLife ResuscitationTechnologies, Inc. (US $1.65 Mn funding)

1995

Dr. Robert Goldman& Dr. Ronald Klatzfound Organ Inc.(total funding US $70 Mn)

1994-1996

Dr. Robert Goldman & Dr. Ronald Klatzsecure Cooperative Research &Development Agreements with: AmericanNational Red Cross (US $2 Mn); USNational Aeronautics & Space Administration(NASA); and US Food & Drug AdministrationCenter for Devices & Radiological Health

“MedicalPioneers”

Vision & LeadershipDr. Ronald Klatz, MD, DO, is a physician, medical scientist, futurist, and innovator. He coined the term "anti-aging medicine" and is recognized as aleading authority in the new clinical science of anti-aging medicine. Dr. Klatz is the physician founder and President of the American Academy of Anti-AgingMedicine (A4M). In 1984, Dr. Klatz was a pioneer in the clinical specialty of preventative medicine: as a principal founder of the National Academy of SportsMedicine (NASM) and researcher into elite human performance and physiology. He has served as a Senior Fellow at the Lincoln Filene Center, Tufts University; as an Affiliate at the Philosophy of Education Research Center, Graduate Schoolof Education, Harvard University. Dr. Klatz is a best-selling author, and is columnist or senior medical editor to several international medical journals.

Dr. Klatz's professional achievements include:~ First physician and founder of the new clinical speciality of anti-aging medicine~ Best-selling author/editor of 40+ books with over 2 million copies in print~ President and physician founder of the American Academy of Anti-Aging Medicine (A4M)~ Academic oversight for AMA/ACCME-approved continuing medical education programs that train over

100,000 physicians, health practitioners, and scientists~ Medical Editor of The World Health Network, leading nonprofit source of non-commercial health

information; and Longevity Magazine(R) eJournal, an award-winning weekly health e-newsletter featuring wellness, prevention, and biotech advancements in longevity

Since 1981, Dr. Klatz has been integral in the pioneering exploration of new therapies for thetreatment and prevention of age-related degenerative diseases. Dr. Klatz is inventor, developer,or administrator of 100-plus scientific patents, including those for technologies for brain resuscitation, trauma and emergency medicine, organ transplant and blood preservation.

The originator of the concept for brain resuscitation, Dr. Klatz was awarded theGold Medal in Science for Brain Resuscitation Technology (1993) and the GrandPrize in Medicine for Brain Cooling Technology (1994).

Dr. Klatz has been named as a Top 10 Medical Innovatorin Biomedical Technology (1997) by the National Instituteof Electromedical Information, and received the GroundBreaker Award in Health Care (1999) with Presidential

Acknowledgment by US President William Jefferson Clinton from TransitionalServices of New York.

1999

American Board ofAnti-Aging HealthCare Practitioners(ABAAHP) administers its first Board Examination

2000

A4M annuallycosponsors/cosupports over 30 anti-agingconferencesaround the world

2006

A4M Anti-AgingConferences partnerswith Tarsus, world's thirdlargest conference management corporation,sales assets in excess ofUS $500 Million

2006

Fellowship inAnti-Aging /RegenerativeMedicinelaunched

1999

A4M launches educational website,www.worldhealth.net,pioneering the dissemination ofadvanced preventativehealth information onthe internet

1997

American Board ofAnti-Aging Medicine(ABAAM) administers the firstBoard CertificationExamination for MDs and DOs

2009

MastersDegree in Anti-AgingMedicine atthe University ofSouth Floridaestablished

2016

Dr. Robert Goldman& Dr. Ronald Klatzdevelop NextBotTM

Robotics Conference& Expo, the world'slargest professional& consumer show-case (in-process)

2012

A4M publishesEncyclopedia ofClinicalAnti-AgingMedicine &RegenerativeBiomedicalTechnologies -15 book compendium

“ParadigmShift”

THE WORLD HEALTH NETWORKwww.worldhealth.netNon-Profit Trusted Source ofNon-Commercial Information in Advanced Preventative Health

Monthly Visitors: 220,000+ pageviews

LONGEVITY MAGAZINE{R} e-JOURNALAward-winning weekly health e-newsletter

covering wellness, prevention, and biotech advancements in longevity.

Subscriber Base: 210,000 (100% opt-in)

Raising the Profile of Anti-Aging Medicine

Total Global Media Reach = 17,120,000 (annually)

American Academy of Anti-Aging MedicineInternet: www.worldhealth.net | www.a4m.com

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Syndicated columns and featured articles in trade, professional, elite sports,

and consumer magazines

Trusted authority in advancedpreventative medicine,dedicated to consumer

outreach and public information

Leading academic publisher for the science of anti-aging medicine and

regenerative biomedical technologies