This

is

With

Host...

Your

Vasculitides

Awesome Associations

RA Rx

Rheum with a View II

100

200

300

400

500

Vasculitides RA RxRheum with

a View IIAwesome

Associations

100

200

300

400

500

100

200

100

200

300300

400400

500500

Involvement of the ophthalmic artery causing sudden

irreversible blindness is 1 sign of this large-sized vasculitis

What is giant cell or temporal arteritis?

Coin lesions+ pulmonary hemorrhage

+ RPGN +saddle-nose deformity

What is Wegener’s granulomatosis?

A.k.a. Kussmaul-Meier disease, this medium-sized vessel

vasculitis is common in Hep B and can show a classic “string of

beads” angiographic picture

What is polyarteritis nodosa?

Papable purpura, arthritis and abdominal pain make up the classic triad of this vasculitis

marked by IgA-immune complex deposition

What is Henoch-Schonlein purpura?

This vasculitis may be associated with uveitis and

erythema nodosum, but most typically known for recurrent oral and genital ulcers, and a

(+) pathergy reaction

What is Behcet’s syndrome?

Most common gynecologic

maligancy in dermatomyositis

What is ovarian cancer?

Painless yellow-brown lesions in palms/soles in

reactive arthritis

What is keratoderma blennorrhagica?

Valvular abnormality in ankylosing spondylitis

What is aortic regurgitation?

Lung condition in scleroderma with diffuse cutaneous involvement

What is pulmonary fibrosis?

Hematologic lab value typically >5x normal in

Adult-onset Still’s disease

What is ferritin?

A folic acid analogue used to treat moderately active RA, it

confers clinical improvement and possible survival benefit

What is methotrexate?

This anti-malarial drug has been shown to reduce inflammation and joint erosions but may also

cause rare ophthalmologic toxicity

What is hydroxychloroquine?

(Plaquenil)

An FDA-approved therapy for RA, this sulfonamide is now a

mainstay of outpatient treatment for inflammatory bowel disease

What is sulfasalazine?

A chimeric monoclonal antibody against TNF-ά, it

requires a pre-treatment PPD to rule out latent TB

What is infliximab?(Remicade)

A recombinant DNA drug, it is produced by combining IgG1 and human TNF receptor—the so-called “master regulator” of inflammation in autoimmune

diseases

What is etanercept?(Enbrel)

View Q1

What is rheumatoid arthritis?

(Boutonniere deformity)

What is gout?

(Ear tophus)

What is dermatomyositis?(shawl sign)

View Q4

What is psoriatic arthritis?

(Dactylitis, DIP involvement, nail pitting)

View Q5

What is scleroderma?

(sclerodactily)

HIV

Buzz wordsin ID

STDs

Drugs for Bugs

200

400

600

800

1000

HIV STDsDrugs for

BugsBuzz words

in ID

200

400

600

800

1000

200

400

200

400

600600

800800

10001000

The risk for this fungal infection increases when the CD4 count

drops below 200 cells/mm3

What is Pneumocystis jiroveci pneumonia?

Multiple brain lesions or

encephalitis in patients with severe HIV

What is Toxoplasmosis?

This HIV drug will make you live your dreams--and nightmares!

What is efavirenz?

(Sustiva)

HIV drug class most commonly associated with fat redistribution syndrome

or lipodystrophy

What are protease inhibitors?

The First and Only Once-Daily Single Tablet HIV Treatment

What is Atripla?(efavirenz/emtricitabine/tenofovir)

Hot tub folliculitis

What is Pseudomonas aeruginosa

infection?

Gardener+ painless nodule on the wrist + palpable axillary lymph node

What is Sporotrichosis?

(Sporothrix schenckii)

Hog farmer from Arkansas+ periorbital edema

+ joint and muscle pains+ eosinophilia

What is Trichinosis?

(Trichinella spiralis)

Post-renal transplant patient+ gram positive rod meningitis

What is Listeriosis?(Listeria moncytogenes)

Seawater exposure+ hemorrhagic bullae/ necrotizing fasciitis

+ septic shock

What is Vibrio vulnificus infection?

Painless penile ulcer with clear base but indurated edges

What is syphilis?(Treponema pallidum)

Painful vesicles in the groin and genital area

What is Herpes simplex type 2 infection?

This tender genital ulcer will make you “cry”!

What is chancroid?(Haemophilus ducreyi)

Small painless vesicle that can cause painful and suppurative

lymphadenopathy

What is Lymphogranuloma venerum?

Beefy red painless ulcer associated with pseudo-buboes,

subcutaneous swelling but not lymph nodes

What is granuloma inguinale?(Calymmatobacterium

granulomatis)

Treponema pallidum

What is Penicillin?

Sporothrix schenkii

What is Itraconazole?

Borrelia burgdorferi

What is Doxycycline?(Tetracyclines)

Bordetella pertussis

What is Erythromycin?

(Macrolides)

Chloroquine-resistantPlasmodium falciparum

What is Mefloquin?

Medical Milestones

1 German and 2 French scientists shared the recently awarded Nobel prize for Medicine for discovering these two viruses causing global

disease and death

What are HPV and HIV?

Thank you for playing