TIB/UB Hannover

2004 2nd IEEE InternationalSymposium on BiomedicalImaging: Macro to Nano

Volume I

Arlington, VA15 -18 April 2004

•IEEE IEEE Catalog Number: 04EX821ISBN: 0-7803-8388-5

Table of Contents

Volume I

A Template-Propagation Method for Segmentation of FilamentousStructures in Electron Tomograms 1Germain, David; Rouault, Tracey; Shen, Weicheng; Subramaniam, Sriram; Zhang, Peijun

A New Approach for 3D Segmentation of Cellular Tomograms Obtained UsingThree-Dimensional Electron Microscopy 5Bartesaghi, Alberto; Lee, Stanton; Lefman, Jon; Orenstein, Jan; Sapiro, Guillermo;Subramaniam, Sriram; Wahl, Sharon

DT-MRI Estimation, Regularization and Fiber Tractography 9Deriche, Rachid; Lenglet, Christophe; Tschumperie, David A.

Hybrid 3D Segmentation Framework 13Metaxas, Dimitris; Chen, Ting

Variational Methods and Partial Differential Equations in Cardiac Image Analysis 17Paragios, Nikos

Image Interpolation Based on Optimal Mass Preserving Mappings 21Tannenbaum, Allen; Zhu, Lei

Dual-Mode Ultrasound Phased Arrays for Imaging and Therapy 25Ebbini, Emad; Yao, Hui

Microbubbles for Ultrasound Diagnosis and Therapy 29Carson, Paul; Fowlkes, J.B.; Kripfgans, Oliver

Velocity Vector Estimation in Synthetic Aperture Flow and B-Mode Imaging 33Jensen, Jorgen

Coded Excitation Methods in Biomedical Ultrasound 37O'Donnell, Matthew; Wang, Yao

Imaging Tissue Mechanical Properties Using Impulsive Acoustic Radiation Force 41Congdon, Amy; Frinkley, Kristin; Nightingale, Kathryn; Palmeri, Mark; Soo, Mary Scott; Trahey, Gregg

Motion Tracking for Palpation Imaging 45Hall, Timothy; Jiang, Jingfeng

3D Intravascular Ultrasound Palpography for Vulnerable Plaque Detection 49Baldewsing, RadjA.; de Korte, Chris L; Mastik, Frits; Schaar, Johannes A.;van der Steen, Anton F. W.; Serruys, Patrick W.

Automated Interpretation of Subcellular Location Patterns 53Murphy, Robert

M-FISH Image Registration and Classification 57Wang, Yu-Ping

Hi

Super-Resolution Tracking of Weak Fluorescent Markers in 3D: Application in Dissecting theMechanics of Chromosome Segregation Using Fluorescence Imaging andMolecular Genetics in Yeast 61Danuser, Gaudenz

Pareto Depth Sampling Distributions for Gene Ranking 65Fleury, Gilles; Hero, Alfred; Swaroop, Anand; Zareparsi, Sepidarseh

Automated Confocal Microscopy: The Way of Achieving Both Quality andQuantity in 3D Image Cytometry 69Kozubek, Michal; Matula, Pavel; Matula,

PetrHigh Resolution Detection of Chromosome Abnormalities with Single CopyFluorescence in situ Hybridization 73Knoll, Joan; Rogan, Peter

Cortical Surface Flattening Using Least Square Conformal Mapping withMinimal Metric Distortion 77Hurdal, Monica; Ju, Lili; Rehm, Kelly; Rottenberg, David; Schaper, Kirt; Stern, Josh

Anatomical Guided Segmentation with Non-Stationary Tissue Class Distributions in anExpectation-Maximization Framework 81Bouix, Sylvain; Grimson, W. Eric; Kikinis, Ron; Pohl, Kilian

Segmentation of 3D Deformable Objects with Level Set Based Prior Models 85Duncan, James; Staib, Lawrence; Tagare, Hemant; Yang, Jing

Skeletonzation by Blocks for Large 3D Datasets: Application to Brain Microcirculation 89Asselot, Didier; Cassot, Francis; Fouard, Celine; Malandain, Gregoire; Marc-Vergnes, Jean-Pierre;Mazel, Christophe; Prohaska, Steffen; Westerhoff, Malte

Segmentation of Connective Tissue in the Optic Nerve Head Using anAnisotropic Markov Random Field 93Burgoyne, Claude; Downs, J. Crawford; Grau, Vicente

Level Set Method for Skull-Stripping MR Brain Images 97Valentino, Daniel; Zhuang, Haihong

Normalization of Joint Image-Intensity Statistics in MRI Using the Kullback-Leibler Divergence 101Warfield, Simon; Weisenfeld, Neil

Microarray Gene Expression Data Analysis 105Ding, Yuhua; Fairiey, Jacqueline; Vachtsevanos, George; Gardner, Andrew; Simeonova, Petia

Robust Unsupervised Tissue Classification in MR Images 109Pham, Dzung; Prince, Jerry

Likelihood Function Analysis for Segmentation of Mammographic Masses forVarious Margin Groups 113Chouikha, Mohamed; Freedman, Matthew; Kinnard, Lisa; Lo, Shih-Chung; Makariou, Erini;Osicka, Teresa; Wang, Paul

Quality Processing of Microarray Image Data Through Image Inpainting and Texture Synthesis 117Liu, Xiaohui; Magoulas, George; O'Neill, Paul

iv

Toward Leukocyte Recognition Using Morphometry, Texture and Color 121Costa, Luciano; Rizzatti, Edgar; Sabino, Daniela; Zago, Marco

4-D Lesion Detection Using Expectation-Maximization and Hidden Markov Model 125Solomon, Jeffrey; Sood, Arun

Segmentation of In-Vitro Endothelial Cell Networks 129Lamberti, Fabrizio; Montrucchio, Bartolomeo

Vascular Segmentation in Three-Dimensional Rotational Angiography Based onMaximum Intensity Projections 133Chung, Albert C.S.; Gan, Rui; Wong, Wilbur C.K.; Yu, Simon

C.H.A New Image Segmentation and Smoothing Model 137Bui, Tien; Gao, Song

An Adaptive Speed Term Based on Generalized Fuzzy Operator for Level Set Segmentation 141Lin, Yazhong; Chen, Wufan

Tissue Color Images Segementation Using Artificial Neural Networks 145Sammouda, Mohamed; Sammouda, Rachid; Niki, Noburu; Benaichouche, Mohamed

Image Segmentation with the Combination of the PCA- andICA-Based Modes of Shape Variation 149Koikkalainen, Juha; Lotjonen, Jyrki

Automatic 2D Segmentation of the Left Ventricle in Tagged Cardiac MRI Using Motion Information 153Arts, Theo; Clarysse, Patrick; Croisille, Pierre; Magnin, Isabelle; Milles, Julien; van Susteren, Anneke

Hierarchical Segmentation of Multiple Sclerosis Lesions in Multi-Sequence MRI 157Ayache, Nicholas; Bensa, Caroline; Chanalet, Stephane; Dugas-Phocion, Guillaume;Gonzalez, Miguel Angel; Lebrun, Christine; Malandain, Gregoire

Combining Fuzzy Logic and Level Set Methods for 3D MRI Brain Segmentation 161Barillot, Christian; Ciofolo, Cybele; Hellier, Pierre

Multiresolution Automatic Segmentation of T1-Weighted Brain MR Images 165Zoroofi, Reza A.; Soltanian-Zadeh, Hamid; Zeydabadi, Mahmood

Meta-Analysis of Functional Imaging Studies Using a Geometric Model of the Cortical Surface 169Burnod, Yves; Tom, Roberto

Large Deformation Minimum Mean Squared Error Template Estimation for Computational Anatomy 173Davis, Brad; Joshi, Sarang; Lorenzen, Peter

3D Model-Based Vascular Tree Analysis Using Differential Geometry 177

Higgins, William; Ritman, Erik; Yu, Kun-Chang

A New Method for Robust Contour Tracking in Cardiac Image Sequences 181Chen, Wufan; Bin, Liang; Zhou, Shoujun

Toward Real-Time, Physically-Correct Soft Tissue Behavior Simulation 185Chandrasekaran, Shivkumar; Koppel, Dan; Wang, Yuan-Fang

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Local Weak Form Geometric Active Contours for Medical Image Segmentation 189

Ho, Gary H.P.; Liu, Huafeng; Shi, Pengcheng

Population Analysis of Knee Cartilage Thickness Maps Using Model Based Correspondence 193Holmes, Andrew; Taylor, Christopher; Waterton, John; Williams, Tomos

Correspondence Recovery in 2-View Mammography 197Anton, Sorin; Goldgof, Dmitry; Li, Lihua; Qiu, Yan; Sarkar, Sudeep; Zhang, Yong

Nerves - Level Sets for Interactive 3D Segmentation of Nerve Channels 201Burgielski, Zbigniew; Hanssen, Nils; Jansen, Thomas; Keeve, Erwin; Lievin, Marc; Ritter, Lutz;von Rymon-Lipinski, Bartosz

Longitudinal Measurements of Signal Intensity as a Potential Marker for CartilageDegeneration in Osteoarthritis 205Bowes, Mike; Kothari, Manish; Naish, Josephine; Taylor, Chris; Vincent, Graham;Waterton, John; White, David

Iterative Image Reconstruction in MRI with Separate Magnitude and Phase Regularization 209Fessler, Jeffrey; Noll, Doug

Matched Filter vs. Least-Squares for Multiple-Coil MRI 213Scheffe, Molly; Zientara, G.P.

Parallel Imaging with Prior Information for Dynamic MRI 217Akao, James; Duensing, Randy; Huang, Feng; Rubin, Andrew

Analysis of Serial MR Images of Joints 221Brooks, Keith; Buckton, Jacky; Changani, Kumar; Hajnal, Joseph; Heckemann, Rolf; Hill, Derek;Holden, Mark; Leung, Kelvin; Reid, David; Rueckert, Daniel; Saeed, Nadeem

Computed Simultaneous Imaging of Multiple Functional Biomarkers 225Wang, Yue; Xuan, Jianhua; Srikanchana, Rujirutana; Szabo, Zsolt; Choyke, Peter

Risk for Alcoholism and Developmental Defects of Specific BrainStructures: A MR Morphometric Study 229Antony, George; Benegal, Vivek; Jayakumar, P.N.

Multi-Resolution Hierarchical Blind Recovery of Biochemical Markers of Brain Cancer in MRSI 233Du, Shuyan; Mao, Xiangling; Sajda, Paul; Shungu, Dikoma

Optimal Variable-Density K-Space Sampling in MRI 237Lee, Jin Hyung; Nishimura, Dwight; Osgood, Brad

On the Regularization of Sense and Space-RIP in Parallel MR Imaging 241

Brooks, Dana; Hoge, William Scott; Kyriakos, Walid; Madore, Bruno

Computer Aided Monitoring of Fibrous Dysplasia Disease in Craniofacial Bones 245

Butman, John; Collins, Michael; Lee, Janice; Yao, Jianhua

Automatic Quantification of Pupil Dilation Under Stress 249Aylward, Stephen; Jomier, Julien; Rault, Erwann

VI

Classification of Breast MRI Lesions Using a Backpropagation Neural Network (BNN) 253Arbach, Una; Reinhardt, Joseph; Stolpen, Alan

Improved Prediction of Prostate Cancer Recurrence Based on an AutomatedTissue Image Analysis System 257Fogarasi, Stephen; Kotsianti, Angeliki; Kumar, Vinay; Ma, Junshui; Pang, Ho-Yuen;Saidi, Olivier; Tabesh, Ali; Teverovskiy, Mikhail; Vengrenyuk, Yevgen; Verbel, David

Distance Contained Centerline for Virtual Endoscopy 261Blaise, Frederic; Jianfei, Liu; Xiaopeng, Zhang

Image-Guidance for Cardiac Surgery Using Dynamic Autostereoscpic Display System 265Dohi, Takeyoshi; Hata, Nobuhiko; Liao, Hongen

Image-Based Rendering and Modeling in Video-Endoscopy 269Koppel, Dan; Wang, Yuan-Fang; Lee, Hua

Method for Assessing Augmented Reality Needle Guidance Using a Virtual Biopsy Task 273Klatzky Roberta; Shelton, Damion; Stetten, George

New Function for Accurate MR-Guided Microwave Ablation UsingVertically Opened 0.5-T MR System 277Demura, Koichi; Haque, Hasnine; Inubushi, Toshiro; Kurumi, Yosimasa; Morikawa, Shigehiro;Naka, Shigeyuki; Sato, Koichiro; Shiomi, Hisanori; Tani, Tohru

A Virtual Reality Based 3D Real-Time Interactive Brachytherapy Simulation of NeedleInsertion and Seed Implantation 280Fenster, Aaron; Wang, Xiaogang

Automatic Detection of Head Refixation Errors in Fractionated Stereotactic Radiotherapy (FSR) 284DeWeese, Theodore; Geng, Jason; He, Shanjin; Kleinberg, Lawrence; Li, Shidong;Liu, Dezhi; Rigamonti, Daniele

Haptic Guided Seeding of MRA Images for Semi-Automatic Segmentation 288Bengtsson, Ewert; Nystrom, Ingela; Tizon, Xavier; Vidholm, Erik

Colon Straightening Based on an Elastic Mechanics Model 292Ackerman, Michael; Li, Jixing; Zhang, Zhan

MRI-Guided Laser Thermal Ablation: Model and Parameter EstimatesRelating MR Thermometry Images to Cell Death 296Breen, Michael; Butts, Kim; Chen, Lili; Saidel, Gerald; Wilson, David

Vorticity Imaging of Diastolic Cardiac Inflow by Phase Contrast MRI 300Chluda, Heather; Cooke, Jason; Gill, Edward; Hertzberg, Jean; Kerwin, William; Shandas, Robin

The Choice of Tracking Features in Ultrasound-Based Strain Imaging Analysis 304Duncan, James; Yu, Weichuan

Bimodal Myocardial Motion Analysis from B-Mode and Tissue Doppler Ultrasound 308Arigovindan, Muthuvel; Hunziker, Patrick; Jansen, Christian; Suhling, Michael; Unser, Michael

Automated Tracking of Multiple Body Parts in Video Recordings of Neonatal Seizures 312Frost, James, Jr.; Karayiannis, Nicolaos; Mizrahi, Eli; Sami, Abdul; Wise, Merrill

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A Posteriori Navigator Echo for Perfusion Imaging of the Liver with Contrast Ultrasound 316Bleuzen, Aurore; Frouin, Frederique; Herment, Alain; Renault, Gilles; Tranquart, Francois

Generalized Robust Point Matching Using an Extended Free-FormDeformation Model: Application to Cardiac Images 320Duncan, James; Lin, Ning

Towards Diffusion Profile Image Registration 324Gee, James; Yushkevich, Paul; Zhang, Hui

DT-MRI Data Visualisation Using the Dual Tree Complex Wavelet Transform 328Kingsbury, Nick; Pena, Alonso; Zymnis, Argyris

Modelling Noise-Induced Fibre-Orientation Error in Diffusion-Tensor MRI 332Alexander, Daniel; Cook, Philip; Parker, Geoffrey

DT-MRI Regularization Using Anisotropic Tensor Field Filtering 336Rodriguez-Florido, Miguel Angel; Ruiz-Alzola, Juan; Westin, Carl-Fredrik

Constrained Free Form Deformation Based Algorithm for Geometric DistortionCorrection of Echo Planar Diffusion Tensor Images 340Ardekani, Siamak; Sinha, Usha

Towards a Shape Model of White Matter Fiber Bundles Using Diffusion Tensor MRI 344Corouge, Isabelle; Gerig, Guido; Gouttard, Sylvain

Maximum-Lesion-Detectability Reconstruction Using Penalized Maximum Likelihood 348Huesman, Ronald; Qi, Jiny

Quasi-Maximum Likelihood Blind Deconvolution of Images Acquired Through Scattering Media 352Bronstein, Alexander; Bronstein, Michael; Zeevi, Yehoshua; Zibulevsky, Michael

Reconstruction of 2D PET Data with Monte Carlo Generated Natural Pixels 356Byrne, Charles; Glick, Stephen; Lemahieu, Ignace; Soares, Ed; Vandenberghe, Stefaan

Analytical Approach to Channelized Hotelling Observer Performance for RegularizedTomographic Image Reconstruction 360

Fessler, Jeffrey; Yendiki, Anastasia

Fourier-Based Forward and Back-Projectors in Iterative Fan-Beam TomographicImage Reconstruction 364Fessler, Jeffrey; Zhang, Yingying

Covariance of Kinetic Parameter Estimators Based on Time Activity CurveReconstructions: Preliminary Study on 1D Dynamic Imaging 368Ahn, Sangtae; Fessler, Jeffrey; Koeppe, Robert; Nichols, Thomas

Nonlinear Dimension Reduction of fMRI Data: The Laplacian Embedding Approach 372

Faugeras, Olivier; Thirion, Bertrand

Incremental Activation Detection in fMRI Series Using Kalman Filtering 376Layahe, Pierre-Jean; Poline, Jean-Baptiste; Roche, Alexis

VIII

Imaging Cortical Oscillations During Sustained Visuomotor Coordination in MEG 380

Baillet, Sylvain; Garnero, Line; Jerbi, Karim; Lachaux, Jean-Philippe

The Influence of Heart Beat and Respiration on Functional Connectivity Networks 384Anton, Jean-Luc; Brett, Matthew; Dodel, Silke; Poline, Jean-Baptiste

Controling the False Positive Detection Rate in Fuzzy Clustering of fMRI Data 388Hossein-Zadeh, Gholam Ali; Jahanian, Hesamoddin; Soltanian-Zadeh, Hamid

Outlier Detection for Robust Region-Based Estimation of the HemodynamicResponse Function in Event-Related fMRI 392Ciuciu, Philippe; lidier, Jerome; Pallier, Christophe; Roche, Alexis

Matching Diffusion Tensor Images Using Gabor Features 396Davatzikos, Christos; Verma, Ragini

A Deformable Brodmann Area Atlas 400Johnston, Patrick; Rasser, Paul; Thompson, Paul; Ward, Philip

Performance-Based Multi-Classifier Decision Fusion for Atlas-BasedSegmentation of Biomedical Images 404Brandt, Robert; Maurer, Calvin, Jr.; Menzel, Randolf; Rohlfing, Torsten; Russakoff, Daniel

Non-Rigid Registration Algorithm with Spatially Varying Stiffness Properties 408Dawant, Benoit; D'Haese, Pierre-Francois; Duay, Valerie; Li, Rui

Building a 4D Atlas of the Cardiac Anatomy and Motion Using MR Imaging 412Chandrashekara, Raghavendra; Lorenzo-Valdes, Maria; Mohiaddin, Raad; Perperidis, Dimitrios;Rao, Anil; Rueckert, Daniel; Sanchez-Ortiz, Gerardo-lvar

Grid-Enabled Automatic Construction of a Two-Chamber Cardiac PDM from a LargeDatabase of Dynamic 3D Shapes 416Boisroberi, Loic; Bossa, Matias; Frangi, Alejandro; Laucelli, Marcos; Huguet, Marina;Olmos, Salvador; Ordas, Sebastian

Finite Element Mesh Generation and Remeshing from Segmented Medical Images 420

Davatzikos, Christos; Mohamed, Ashraf

Automated Identification of Microstructures on Histology Slides 424Coward, Chip; Garcia, Fernando; Katsinis, Constandine; Petushi, Sokol; Tozeren, Aydin

Cortical Surface Parameterization by P-Harmonic Energy Minimization 428Joshi, Anand; Leahy, Richard; Shattuck, David; Thompson, Paul

Diffusion Smoothing on Brain Surface via Finite Element Method 432Chung, Moo; Taylor, Jonathan

Clustering on Image Boundary Regions for Deformable Model Segmentation 436Chaney, Edward; Pizer, Stephen; Rao, Manjari; Stough, Joshua

A Probabilistic Framework for the Detection and Tracking in Time of Multiple Sclerosis Lesions 440Greenspan, Hayit; Shahar, Alton

IX

Modeling of Tumor Conspicuity in Hepatic CT Images: Combined Compartment andVascular Models 444Bezy-Wendling, Johanne; Coupe, Pierrick; Kretowski, Marek

Analysis of Time-Varying Psoriasis Lesion Image Patterns 448Delgado Gomez, David; Ersboll, Bjarne; Maletti, Gabriela; Nielsen, Allan

Relationship Between the Morphology and Functionality of Articular Surfaces.Applications to 3D Navigation 452Guillard, Gwenael; Hamitouche, Chafiaa; Cano, Julio Daniel Gil; Roux, Christian; Stindel, Eric

Measuring Blood Cells Velocity in Microvessels from a Single Image: Application toIN VIVO and IN SITU Confocal Microscopy 456Ayache, Nicholas; Lacombe, Frangois; Le Goualher, Georges; Malandain, Gregoire;Perchant, Aymeric; Savoire, Nicolas

Parametric Analysis of Main Motion: Application to the Assessment of Left VentricularWall Motion by MR Imaging 460Delouche, Annie; Diebold, Benoit; Frouin, Frederique; Jolivet, Odile; Kachenoura, Nadjia;Mousseaux, Elie; Redheuil, Alban; Ruiz Doninguez, Cinta,

Meshfree Cardiac Motion Analysis Using Composite Material Model andTotal Lagrangian Formulation 464Liu, Huafeng; Shi, Pengcheng; Sinusas, Albert; Wong, Alexandra; Wong, Ken

Cardiac Motion Tracking in Tagged MR Images Using a 4D B-Spline Motion Modeland Nonrigid Image Registration 468Chandrashekara, Raghavendra; Mohiaddin, Raad; Rueckert, Daniel

Effects of Breathing Motion on the Spatial Resolution in Microscopic ImagingTechniques of Rodents 472Badea, Cristian; Hedlund, Laurence; Johnson, G. Allan; Mai, Wilfried; Wheeler, Charies

Tracking Fluorescent Cells with Coupled Geometric Active Contours 476Olivo-Marin, Jean-Christophe; Zhang, Bo; Zimmer, Christophe

Respiratory Motion Estimation from Slowly Rotating X-Ray Projections 480

Baiter, James; Fessler, Jeffrey; Zeng, Rongping

Non-Rigid Image Transformation for Assessing Changes in Fluorescence ImagingData of Molecular Activity in Time-Dependent Geometries 484Marias, Kostas; Ntziachristos, Vasilis; Orphanoudakis, Stelios; Ripoll, Jorge

Image Analysis of Doppier Echocardiography for Patients with Atrial Fibrillation 488Feinberg, Micha; Greenspan, Hayit; Shechner, Oron; Sheinovitz, Mickey

Three-Dimensional Reconstruction of Tracked Freehand Ultrasound Using Non-Rigid Registration 492Joosten, Krista; Letteboer, Marloes; Niessen, Wiro; Penney, Graeme; Viergever, Max

Automatic Segmentation of Prostate Boundaries from Abdominal UltrasoundImages Using Priori Knowledge 496Rousseau, Jean; Vermandel, Maximilien; Betrouni, Nacim; Maouche, Salah

Advantages in Using Multi-Frequency Driving to Enhance Ultrasound Contrast MicrobubbleNon-Linearities for Optimizing Echo Particle Image Velocimetry Techniques 500Hertzberg, Jean; Kim, Hyoung-Bum; Mukdadi, Osama; Shandas, Robin; Zheng, Hairong

Numerical Modeling of Ultrasound Imaging Using Contrast Agents for Particle ImageVelocimetry IN VIVO 504Mukdadi, Osama; Shandas, Robin; Kim, H.B.; Hertzberg, J.R.

Quantitation of Regional Myocardial Function During Short-Lived Events with Ultrasound Imaging 508Belohlavek, Marek; Korinek, Josef; McMahon, Eileen; Urheim, Stig; Wang, "Jianwen

Atomic Layer Deposition for Fabricating Capacitive Micromachined UltrasonicTransducers: Initial Characterization 512Bright, Victor; Hertzberg, Jean; Kim, Hyoung; Liu, Lingli; Mukdadi, Osama; Shandas, Robin

A Study of Pressure-Dependent Attenuation in Ultrasound Contrast Imaging 516Eckersley Robert; Noble, J. Alison; Tang, Meng-Xing

Monitoring Angiogenesis in Human Melanoma Xenografts Using Contrast-Enhanced Ultrasound 520Forsberg, Flemming; James, Kathryn; Lewin, Peter; Liu, Ji-Bin; Nazarian, Levon;Potoczek, Magdalena; Ro, Raymond

Interactive Rendering of Real-Time Volumetric Ultrasound Images 524Bredthauer, Gregory; von Ramm, Olaf

A Novel Closed Form Solution for Ultrasound Calibration 527Boctor, Emad; Choti, Michael; Fichtinger, Gabor; Hager, Gregory; Taylor, Russell; Viswanathan, Anand

Quantitative Analysis of Circumferential Plaque Distribution in Human CoronaryArteries in Relation to Local Vessel Curvature 531Braddy, Kathleen; Brennan, Theresa; Chandran, Krishnan; Coskun, A. limit; Feldman, Charles;Medina, Ruben; Olszewski, Mark; Rossen, James; Sonka, Milan; Stone, Peter;Vigmostad, Sarah; Wahle, Andreas

The Accuracy of Blood Velocity Measurement Using Ultrasound 535Cosgrove, John; Greated, Clive; Hoskins, Peter; Meagher, Siobhan; Poepping, Tamie

A Software Package for Portable Three-Dimensional Ultrasound Imaging 539Chen, Xinlin; Xu, X. George; Zhang, Tiantian

Simultaneous Elastic Image Registration and Elastic Modulus Reconstruction 543Barbone, Paul; Doyley, Marvin; Gokhale, Nachiket; Oberai, Assad; Richards, Michael

Speckle Reduction on Ultrasound Image by Variational Methods and AdaptiveLagrangian Multipliers 547Barillot, Christian; Hellier, Pierre; Ogier, Arnaud

A Method for Reconstructing Label Images from a Few Projections, asMotivated by Electron Microscopy 551Herman, Gabor; Liao, Hstau

A Fast Fully 4D Incremental Gradient Reconstruction Algorithm for List Mode PET Data 555Asma, Evren; Leahy, Richard; Li, Quanzheng

xi

Three-Dimensional Multi-Resolution Statistical Reconstruction for Tomosynthesis 559

Chen, Pei; Barner, Kenneth

A "Brick" Caching Scheme for 3D Medical Imaging 563Li, Jianchun; Papachristou, Christos; Shekhar, Raj

3D Region of Interest X-Ray CT for Geometric Magnification from Multiresolution Acquisitions 567Scheunders, Paul; Tisson, Greg; Van Dyck, Dirk

Ultra-Fast 3D Filtered Backprojection on Commodity Graphics Hardware 571Mueller, Klaus; Xu, Fang

Image Reconstruction from Truncated Cone-Beam Projections 575Schomberg, Hermann

Alternating Minimization Algorithm for Dual Energy X-Ray CT 579Benac, Jasenka; 0'Sullivan, Joseph; Williamson, Jeffrey

Genetic Influences on Human Brain Morphology 583Cannon, Tyrone; Huttunen, Matti; Lonnqvist, Jouko; Poutanen, Veli-Pekka; Salonen, 0/7/;Standertskjdld-Nordenstam, Cari-Gustav; Thompson, Paul; Toga, Arthur; Tran, Helen;Valanne, Leena; van Erp, Theo; Wobbekind, Amber; Kaprio, Jaakko

Morphological Classification of Medical Images Using Nonlinear Support Vector Machines 587

Davatzikos, Christos; Karacali, Bilge; Lao, Zhiqiang; Shen, Dinggang; Xue, Zhong

Inverse Consistent Registration with Object Boundary Constraints 591Christensen, Gary

Shape Averaging with Diffeomorphic Flows for Atlas Creation 595Avants, Brian; Gee, James

Challenges and Progress Toward Quantitative Deformation Morphometry of Gyral Anatomy 599Cardenas, Valerie; Drapaca, Corina; Studholme, Colin; Weiner, Michael

Brain Warping with Implicit Representations 603Huang, Sung Cheng; Leow, Alexia; Protas, Hillary; Thomspon, Paul

Dynamic SPECT Imaging: Exploring a New Frontier in Medical Imaging 607Gullberg, Grant

Tracer Kinetic Parametric Imaging in PET 611Carson, Richard

Phase - Correlated Dynamic CT 616Kachelrie, B

Level Set Methods for Dynamic Tomography 620Karl, William; Shi, Yonggang

Imaging the Evolution of Three-Dimensional Myocardial Strains Using a Fast MRImaging Technique 624Osman, Nael; Prince, Jerry; Sampath, Smita

xii

Spatio-Temporal Modeling and Adaptive Acquisition for Cardiac MRI 628Aggarwal, Nitin; Bandyopadhyay, Saptarshi; Bresler, Yoram

3DSIicer 632Halle, Michael; Kikinis, Ron; Pieper, Steve

Simulation of Advanced Ultrasound Systems Using Field II 636Jensen, Jorgen

Scirun/Biopse: Integrated Problem Solving Environment for Bioelectric Field Problemsand Visualization Bioelectric Field Problems and Visualization ".. 640Brooks, Dana; de St. Germain, Davison; Johnson, Christopher; MacLeod, Rob;Parker, Steven; Weinstein, David

Duff: Software Tools for Visualization and Processing of Neuroimaging Data 644MacKenzie-Graham, Allan; Shattuck, David; Toga, Arthur

Software Process: The Key to Developing Robust, Reusable and MaintainableOpen-Source Software 648Ibanez, Luis; Martin, Kenneth; Schroeder, William

Electromagnetic Brain Imaging Using Brainstorm 652Baillet, Sylvain; Leahy, Richard; Mosher, John

Automatic Quantification of Microtubule Dynamics 656Duncan, James; Hadjidemetriou, Stathis; Toomre, Derek; Tuck, David

Extended Depth-of-Focus for Multi-Channel Microscopy Images: A Complex Wavelet Approach 660Berent, Jesse; Forster, Brigitte; Sage, Daniel; Unser, Michael; Van De Ville, Dimitri

A Multiple Target Approach for Single Quantum Dot Tracking 664Bonneau, Stephane; Cohen, Laurent; Dahan, Maxime

Deep Tissue Imaging Approaches by Direct Capture of Two-Photon Absorption 668Fischer, Martin; Tian, Peifang; Wagner, Wolfgan; Warren, Warren S.; Ye, Tong; Yurtsever, Gunay

Reduction of Physiological Interference in Optical Functional Neuroimaging UsingEigenvector-Based Spatial Filtering 672Boas, David; Brooks, Dana; Franceschini, Maria; Zhang, Yiheng

A Method for Dynamically Suppressing Sidelobes in Optical Coherence Tomography 676Boppart, Stephen; Carney, Paul; Marks, Daniel

3-D Multispectral Monitoring of Living Cell Signaling Using Confocal-lmagingand FPGA Processing 680Budge, Scott; Perrine, Kenneth; Seim, Thomas; Solinsky, James;Sowa Resat, Marianne; Wiley, H. Steven

Development of a Percutaneous Optical Imaging System for Tracking VascularGene Expression: An Ultrasound-Guided Ex Vivo Feasibility Study 684Kar, Sourav; Kumar, Ananda; Yang, Xiaoming

In Vivo Multi Lifetime Discrimination Using Time Domain Fluorescence Imaging 688

Belenkov, Alexander; Lesage, Frederic

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An Integrated Fibered Confocal Microscopy System for in vivo and IN SITUFluorescence Imaging - Applications to Endoscopy in Small Animal Imaging 692Berier, Frederic; Genet, Magalie; Le Goualher, Georges; Perchant, Aymeric; Viellerobe, Bertrand

Evaluation of a Similarity-Based Elastography Technique Using Four Similarity Metrics 696Miga, Michael; Rothney, Megan; Washington, Chad

Subpixel Registration in Renal Perfusion MR Image Sequence 700Ho, Chien; Moura, Jose; Sun, Ying

Local Feature Matching Using Entropic Graphs .7 704Carson, Paul; Hero, Alfred; Meyer, Charles; Neemuchwala, Huzefa

2D-3D Vascular Registration Between Digital Subtraction Angiographic (DSA) andMagnetic Resonance Angiographic (MRA) Images 708Chan, H.M.; Chung, Albert; Wells, William, III; Yu, Simon

Multi-Channel Registration of Diffusion Tensor Images Using Directional Information 712

Pajevic, Sinisa; Pierpaoli, Carlo; Rohde, Gustavo

Ground Truth Data for Validation of Nonrigid Image Registration Algorithms 716Chou, Yi-Yu; Skrinjar, Oskar

Model Based Symmetric Information Theoretic Large Deformation Multi-Modal Image Registration 720Daws, Brad; Joshi, Sarang; Lorenzen, Peter

A Unified Feature-Based Registration Method for Multimodality Images 724

Rangarajan, Anand; Zhang, Jie

Quadrature-Based Image Registration Method Using Mutual Information 728Fookes, Clinton; Maeder, Anthony

Differential Evolution with Powell's Direction Set Method in Medical Image Registration 732Dony, Robert; Xu, Xiaoyan

An Extendable Registration Similarity Metric for Anatomical Image Sequence Alignment 736

Belford, Geneva; Gabriel, Michael; Zhao, Rongkai

Surface Matching Algorithms for Computer Aided Reconstructive Plastic Surgery 740Bhandarkar, Suchendra; Chowdhury, Ananda; Tang, Yarong; Tollner, Ernest; Yu, Jack

Symmetry-Based 3D Brain Reconstruction 744Bertrand, Louise; Fan, Yingli; Gefen, Smadar; Nissanov, Jonathan

Penalized Likelihood Transmission Image Reconstruction: Unconstrained Monotonic Algorithms 748Fessler, Jeffrey; Srivastava, Somesh

A Geometric Approach to Parameter Estimation from Tomographic Data 752Chernyavskiy, Alexey; Whitaker, Ross

Compact Representation of PET 3D System Response Matrices 756Adler, Stephen; Kudrolli, Haris; Nevin, John; Romanov, Leonid; Worstell, William

XIV

Volterra-Type Nonlinear Image Restoration of Medical Imagery Using Principal Dynamic Modes 760Do, Synho; Jeong, Jeong-Won; Kim, Tae-Seong; Marmarelis, Vasilis; Shin, Dae

A Bayesian Approach to Image Restoration 764Borga, Magnus; Knutsson, Hans; Wrangsjo, Andreas

Robust Filtering Strategies for Soft Tissue Young's Modulus Characterization 768Liu, Huafeng; Shi, Pengcheng; Sinusas, Albert

Analysis of Spatial-Temporal Regularization Methods for Linear Inverse Problems froma Common Statistical Framework 772Brooks, Dana; Ghodrati, Alireza; Zhang, Yiheng

New Method of Image Reconstruction from Projections 776Grigoryan, Artyom

A New Imaging Method in Diffraction Tomography Based on the Topoiogical Derivative 780Feijoo, Gonzalo

Fast Spiral Fourier Transform for Iterative MR Image Reconstruction 784Donoho, David; Lee, Jin Hyung; Lustig, Michael; Tsaig, Jacob

An Adaptive Window Approach for Poisson Noise Reduction and StructurePreserving in Confocal Microscopy 788Kervrann, Charles; Trubuil, Alain

Regional LungVentilation from Volumetric CT Scans Using Image Warping Functions 792Albert, Richard; Beck, Kenneth; Carlson, Katherine; Hoffman, Eric; Krishnan, Smita;Reinhardt, Joseph; Simon, Brett

Search Space Partitioning Using Convex Hull and Concavity Features forFast Medical Image Retrieval 796Mlsna, Phillip; Sirakov, Nikolay

Using Grey-Level and Shape Information for Decomposing Proteins in 3D Images 800Mata, Susana; Sintorn, Ida-Maria

Quantitative Analysis of Volumetric Two-Photon Laser Scanning Microscopy Data 804Friedman, Beth; Ifarraguerri, Agustin; Kleinfeld, David; Lev-Ram, Varda; Schaffer, Chris;Squier, Jeff; Thompson, Beveriy; Tsai, Philbert; Tsien, Roger

A Minimum Reliable Scale Selection in 3D Images 808Ge, Yaorong; Wyatt, Christopher

Enhanced Snake-Based Segmentation of Vocal Folds 812Allin, Sonya; Dailey, Seth; Galeotti, John; Stetten, George

Image Enhancement by the Tensor Transform 816Arslan, Fatma; Grigoryan, Artyom

Trilateral Filtering for Biomedical Images 820Chung, Albert C.S.; Wong, Wilbur C.K.; Yu, Simon C.H.

xv

Evaluation of Reproducibility for Perfusion Assessment of Tumors in MRI 824

Ashton, Edward; Kim, Seung

Cardiac MR Image Segmentation: Quality Assessment of STACS 828Ho, Chien; Moura, Jose; Pluempitiwiriyawej, Charnchai; Wu, Yi-Jen Lin

Model-Observer Based Quality Measures for Decompressed Medical Images 832Li, Dunling; Loew, Murray

Medical Software Control Quality Using the 3D Mojette Projector 836Beaumont, Stephane; Guedon, Jean-Pierre; Normand, Nicolas; Servieres, Myriam

Focal Cartilage Defect Progression Detection: Measurement of Precision and Variationin Natural Characteristics of Cartilage Thickness Maps Derived from 3D MRI Data 840Barbu-Mclnnis, Monica; Tamez-Pena, Jose; Totterman, Saara

An Exploratory Approach to Modelling Effective Connectivity 844Rajapakse, Jagath; Yang, Kanyan

Identification of a Large-Scale Functional Network in Functional Magnetic Resonance Imaging 848Bellec, Pierre; Benali, Habib; Doyon, Julien; Jbabdi, Saad; Jolivet, Odile; Marrelec, Guillaume;Pelegrini-lssac, Melanie; Perlbarg, Vincent

Selection of Spatially Independent Components to Explain Functional Connectivity in fMRI 852Bellec, Pierre; Benali, Habib; Jbabdi, Saad; Marrelec, Guillaume; Pertbarg, Vincent

Combining Voxel Intensity and Cluster Extent with a Permutation Test Framework 856Hayasaka, Satoru; Nichols, E.; Thomas, B.

Semi-Blind Deconvolution of Neural Impulse Response in Event-Related fMRIUsing a Gibbs Sampler 860Ciuciu, Philippe; lidier, Jerome; Makni, Salima; Poline, Jean-Baptiste

Fusion of Simultaneous fMRI/EEG Data Based on the Electro-Metabolic Coupling 864Baillet, Sylvain; Garnero, Line; Lahaye, Pierre-Jean; Poline, Jean-Baptiste

Reversible Jump Markov Chain Monte Carlo Signal Detection in FunctionalNeuroimaging Analysis 868Galatsanos, Nikolas; Lukic, Ana; Strother, Stephen; Wernick, Miles; Yang, Yongyi

Analysis of Correlated Activity in fMRI Data by Artificial Neural Networks 872Dodel, Silke; Herrmann, J.M.; Voultsidou, Marotesa

An fMRI Activation Method Using Complex Data 876Logan, Brent; Rowe, Daniel

Reconstruction of 3D Dense Cardiac Motion from Tagged MR Sequences 880Chang, Hsun-Hsien; Ho, Chien; Moura, Jose; Sato, Kazuya; Wu, Yijen

Dynamic Range of Harmonic Phase Magnetic Resonance Imaging (HARP-MRI) 884Ness-Aiver, Moriel; Parthasarathy, Vijay; Prince, Jerry

XVI

Combined Tag Tracking and Myocardium Motion Reconstruction from PlanarTagged MR Image Data Without User-Defined Myocardial Contours 888Deng, Xiang; Denney, Thomas, Jr.

Accelerated Parallel Magnetic Resonance Imaging by Adaptive K-Space Sampling 892Aggarwal, Nitin; Bresler, Yoram

Motion Artifact Reduction in MRI Through Generalized DFT 896Andersson, Mats; Borga, Magnus; Knutsson, Hans; Sigfridsson, Andreas; Wigstrom, Lars

Unique Planar Color Coding of Fiber Bundles and Its Application to Fiber Integrity Quantification 900Hahn, Horst; Peitgen, Heinz; Rexilius, Jan; Schlueter, Mathias; Stieltjes, Bram

4D Image Warping for Measurement of Longitudinal Brain Changes 904Shen, Dinggang

Consistent Groupwise Non-Rigid Registration for Atlas Construction 908Bhatia, K.K.; Edwards, A.D.; Hajnal, J.V.; Puri, B.K; Rueckert, D.

A Simulated Charged Fluid for Deformable Models 912Chang, Herng-Hua; Valentino, Daniel

Isolation and Minimization of Effects of Motion on fMRI Using Multiple Reference Images 916Krolik, Jeffrey; Liao, Rui; McKeown, Martin

Symmetric, Transitive, Geometric Deformation and Intensity Variation InvariantNonrigid Image Registration 920Skrinjar, Oskar; Tagare, Hemant

Non-Rigid Registration of Shapes via Diffeomorphic Point Matching 924Guo, Hongyu; Joshi, Sarang; Rangarajan, Anand; Younes, Laurent

Directional Interpolation of Sparsely Sampled Cone-Beam CT Sinogram Data 928Aach, Til; Bertram, Matthias; Rose, Georg; Schaefer, Dirk; Wiegert, Jens

Exact 3D Cone-Beam Reconstruction from Projections Obtained Over a WobbleTrajectory on aC-Arm 932Prince, Jerry; Ramamurthi, Krishnakumar; Strobel, Norbert

Gridding-Based Three-Dimensional Image Reconstruction from ProjectionsWith Arbitrary Directions 936Penczek, Pawel; Renka, Robert; Schomberg, Hermann

| An Observer Model Evaluation of Simultaneous Reconstruction and MotionI estimation for Emission Tomography 940I Ceo, Zixiong; Gilland, David; Mair, Bernard; Tsui, Benjamin

llJarebral Aneurysm Hemodynamics Modeling from 3D Rotational Angiography 944s, James; Castro, Marcelo; Cebral, Juan; Putman, Christopher

lple-lrnage Computed Tomography 948stasio, Mark; Brankov, Jovan; Chapman, Dean; Li, Jun; Muehleman, Carol;

/c/c, Miles; Zhong, Zhong

XVII

A Regularized Approach to Freehand Ultrasound Elastography of Breast Lesions 952Frouin, Frederique; Herment, Alain; Insana, Michael; Lindfors, Karen; Mai, Jerome;Pellot-Barakat, Claire; Tsou, Jean; Von Behren, Patrick

Comparison of Doppler Ultrasound Flow Resistance Indices in Beta-Thalassemic,Sickle Cell Anemic and Control Mice 956Cloutier, Guy; Foster, F. Stuart; Stoyanova, Ekatherina; Trudel, Marie

Oblique Needle Segmentation for 3D TRUS-Guided Robot-Aided TransperinealProstate Brachytherapy 960Downey, Donal; Fenster, Aaron; Gardi, Lori; Wei, Zhouping

Coded Pulse Excitation for Ultrasonic Strain Imaging 964Insana, Michael; Liu, Jie

3-D High Resolution Images of Ultrasonic Transmission Tomography Compared toMagnetic Resonance and Optical Images 968Do, Syn-Ho; Huang, Chengzheng; Jeong, Jeong-Won; Kim, Tae-Seong;Marmarelis, Vasilis; Shin, Dae; Singh, Manbir

Spatial Angular Compounding for Ultrasound Elastography 972Chen, Quan; Madsen, Ernest; Techavipoo, Udomchai; Varghese, Tomy; Zagzebski, James

Detecting Cortical Activations from fMRI Data Using a Recursive STAP Algorithm 976Holland, Scott; Schmithorst, Vincent; Thompson, Elizabeth

Detection of Functional Networks in the Resting Brain 980He, Yong; Jiang, Tianzi; Lu, Yingli; Weng, Xuchu; Zang, Yufeng

Independent Component Analysis of Complex-Valued Functional Magnetic ResonanceImaging Data by Complex Nonlinearities 984Adali, Tulay; Calhoun, Vince; Yiou, Li

Dimensionality and Degrees of Freedom in fMRI Data Analysis - A Comparative Study 988Borga, Magnus; Knutsson, Hans; Lundberg, Peter; Rydell, Joakim

Selection of Temporal Models for Event-Related fMRI 992Ciuciu, Philippe; Donnet, Sophie; Lavielle, Marc; Poline, Jean-Baptiste

Simultaneous Estimation of Kinetic Parameters and the Input Function fromDCE-MRI Data: Theory and Simulation 996Han, Zhu; Liu, K.J. Ray; Wang, Yue; Wang, Z. Jane

Solving for Motion and Activation Simultaneously in an fMRI Experiment withMultiple Stimulus Conditions 1000Atkins, M.; Orchard, Jeff

Relevance Vector Machine Learning of Functional Neuroimages 1004

Galatsanos, Nikolaos; Likas, Aristidis; Lukic, Ana; Tzikas, Dimitris; Wernick, Miles

Clustering-Based Framework for Comparing fMRI Analysis Methods 1008Golestani, Ali-Mohammad; Hossein-Zadeh, Gholam-Ali; Soltanian-Zadeh, Hamid

XVIII

Comparison of Supervised and Unsupervised Linear Methods for RecoveringTask-Relevant Activity in EEG 1012Gerson, Adam; Luo, An; Sajda, Paul

Constrained Projection Reconstruction for Reduced Encoding MR Diffusion Tensor Imaging 1016

Hsu, Edward; Jiang, Yi

Distortion Correction Using Mutual Information in 3D Diffusion Tensor Microscopy 1020Hsu, Edward; Mistry, Nilesh

A Level Set Method for Building Anatomical Connectivity Paths Between Brain Areas Using DTI 1024Bellec, Pierre; Benali, Habib; Jbabdi, Saad; Marrelec, Guillaume; Peribarg, Vincent

Recovery of Intra-Voxel Structure from High Angular Resolution DWI 1028Chen, Yunmei; Guo, Weihong; Liu, Yijun; Vemuri, Baba; Zeng, Qingguo; He, Guojun

Statistical Analysis of a Nonlinear Estimator for ADC and Its Application to OptimizingDiffusion Weighting Factors _ 1032Chen, Yunmei; Mareci, Thomas; Ozarslan, Evren; Vemuri, Baba; Wang, Zhizhou

Fiber Orientation Mapping Using Generalized Diffusion Tensor Imaging 1036Mareci, Thomas; Ozarslan, Evren; Vemuri, Baba

PDE Denoising of MR Diffusion Tensor Imaging Data 1040

Chen, Bin; Hsu, Edward

Volume II

A New Method to Measure Cross Sectional Area of Vessels in MRI Image and ItsApplication in Stenosis Detection 1043Dong, Ming; Haacke, E. Mark; Jiang, Jing

Improved Reconstruction of Dynamic Cardiac Perfusion MRI with Use of a Reference Frame 1047Di Bella, Ed; Riabkov, Dmitri

A Technique for Improving Tag Contrast Persistence in SSFP MRI ImagingUsing Adaptive Flip Angle 1051Ibrahim, El-Sayed; Osman, Nael

Detecting the Onset of Myocardial Contraction for Establishing InverseElectro-Mechanical Coupling in XMR Guided RF Ablation 1055Chandrashekara, Raghavendra; Hill, Derek; Razavi, Reza; Rhode, Kawal;Rueckert, Daniel; Sanchez-Ortiz, Gerardo; Sermesant, Maxime

Spatial-Spectral FAT Suppression in Phase-Contrast Coronary Flow Imaging 1059Bayram, Ersin; Hamilton, Craig; Hundley, W. Gregory; Kraft, Robert

Reconstruction of the Heart Boundary from Undersampled Cardiac MRI Using FourierShape Descriptors and Local Basis Functions 1063Arridge, Simon; Hill, Derek; Kastanis, lason; Ravazi, Reza; Silver, Avi

Simplified Gamma-Variate Fitting of Perfusion Curves 1067Chan, Antoinette; Nelson, Sarah

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