tm. technical milestones conceptualization market analysis methionine study ingredient study...
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TM
Technical Milestones
Conceptualization Market analysis
Methionine study
Ingredient study
Formulation lab study Field trials
THE NEED
DL- Methionine price fluctuation
Cost effect protein source
Natural replacer
Methionine price and monopoly
Technical Milestones
Conceptualization Market analysis
Methionine study
Ingredient study
Formulation lab study Field trials
November 2009
Amino acids are available and synthesized in all living forms, the order of importance of the same would differ. Thus, essential amino acids for one category of life can be a non essential and easily synthesized in vivo by another organismThus,• Replacing DL-Methionine by a source of natural origin??• Functional replacement of DL- Methionine ??• Improving digestibility of rations for better methionine assimilation ??• Using precursors of Methionine and enzyme systems for in vivo biotransformation??
Technical Milestones
Conceptualization Market analysis
Methionine study
Ingredient study
Formulation lab study Field trials
January 2010 Comparable products in marketPricing placement of productEfficacy reports from known sourcesComplete market analysis to justify product development
Technical Milestones
Conceptualization Market analysis
Methionine study
Ingredient study
Formulation lab study Field trials
March 2010Research compilation and analysis for various international and domestic published papersNarrowing down of selective known functional rolesStudy of precursors and enzyme pathwaysStudy of analogues
Technical Milestones
Conceptualization Market analysis
Methionine study
Ingredient study
Formulation lab study Field trials
November 2010Herbal options from known sourcesNatural ingredients mimicking functions of methionine Precursors in plantsHerbs and natural substances improving digestibility of methionine from common livestock dietsUse of sulfur donors and methyl donors in natural forms
Technical Milestones
Conceptualization Market analysis
Methionine study
Ingredient study
Formulation lab study Field trials
January 2011
Combination of selected ingredients ,stability, and interactionAmino acid content of these formulations Dosage and DL-Methionine comparison of dosage
Technical Milestones
Conceptualization Market analysis
Methionine study
Ingredient study
Formulation lab study Field trials
2011 to 2015
Trials,Lab scale to field scale to probable customer trialsTotal trials conducted – 12Lab scale - 2Field scale – 9Probable customer trial - 2
KIFAY is a DL-methionine replacer of natural origin. It improves the availability of
essential amino acid methionine and has a methionine sparing effect on the body.
KIFAY helps regulate all functions of methionine in the body. It is a combination of
various herbs rich in sulfur entities and source of methionine complementing active
bio-constituents.
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APPLICATION,MECHANISM OF ACTION AND USPs
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KIFAY - Mechanism of action
Improves amino acid digestibility of ingredients.
SAMe rich fractions give methionine sparing effect and reduces the methionine requirement
Functional replacers in the formulation compensate and surpass performance of DL-Methionine as a growth promoter and immunomodulant.
Plants rich in cofactor Vitamin B12 which is important methionine uptake and metabolism.
Intestinal microbiodata modulation to improve methionine uptake and nitrogen recycling.
Application of KIFAY -steps
All replacement are independent of final proximate analysis including total crude protein levels
Replace Mass by Mass of KIFAY for DL-Methionine.
Replace 75 % of DL-Methionine by KIFAY
Calculate DL-Methionine required/Recommended
Formulate least cost matrix ( All parameter set)
Application of KIFAY –steps, eg.
All replacement are independent of final proximate analysis including total crude protein levels
Replace Mass by Mass of KIFAY for DL-Methionine.
Replace 75 % of DL-Methionine by KIFAY
Calculate DL-Methionine required/Recommended
Formulate least cost matrix ( All parameter set)• CP – 23 %, Typical energy – 3200 ME/Kg
• Methionine - 0.5 % , 5 Kg per ton of feed
• 3.75 kg of DLM replace by 3.75 Kg of KIFAY
• Final diet will have 3.75 Kg KIFAY + 1.25 Kg DLM
USPsLeast cost formulation
Maximum profitability even from adding less protein in diet , thus reducing the cost by improving bioavailability of amino acids.
Inherent hepatoprotectant effect in the formulation
Natural and effective DLM replacer
Dosage
DL-Methionine
Calculate total methionine requirement per ton of feed per phase( Pre-
starter, starter, grower and finisher separately)
Replace 75 percent of artificial methionine by KIFAY
75:25
www.vinayakcorporation.com
A product ofVINAYAK INGREDIENTS (INDIA) PRIVATE LIMITED
Corporate Address :Unit No.116, 1st Floor, Cama Industrials Estate,
Sunmill Compound Lower Parel - West, Mumbai - 400 013. INDIA.
Tel : +91 22 40560400 Facsimile - +91 – 22 - 40560404
mail : [email protected]
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