towards a model-based integration of co-registered electroencephalography/functional magnetic...

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Towards a model-based integration of co- registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes by I. Bojak, Thom F. Oostendorp, Andrew T. Reid, and Rolf Kötter Philosophical Transactions A Volume 369(1952):3785-3801 October 13, 2011 ©2011 by The Royal Society

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Page 1: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance

imaging data with realistic neural population meshes

by I. Bojak, Thom F. Oostendorp, Andrew T. Reid, and Rolf Kötter

Philosophical Transactions AVolume 369(1952):3785-3801

October 13, 2011

©2011 by The Royal Society

Page 2: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

(a) Neural population model surface (blue) between the Civet interfaces of grey matter with white matter (yellow) and cerebrospinal fluid (orange).

I. Bojak et al. Phil. Trans. R. Soc. A 2011;369:3785-3801

©2011 by The Royal Society

Page 3: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

(a) Before (top) and after (bottom) pruning.

I. Bojak et al. Phil. Trans. R. Soc. A 2011;369:3785-3801

©2011 by The Royal Society

Page 4: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

(a) Head model as extracted from structural magnetic resonance imaging.

I. Bojak et al. Phil. Trans. R. Soc. A 2011;369:3785-3801

©2011 by The Royal Society

Page 5: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

(a) Direct connections , , and within the cortical volume are concatenated to the shortest route .

I. Bojak et al. Phil. Trans. R. Soc. A 2011;369:3785-3801

©2011 by The Royal Society

Page 6: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

(a) Projection vectors for vertex si and voxel vj, and resulting weights from high (red) to low (blue).

I. Bojak et al. Phil. Trans. R. Soc. A 2011;369:3785-3801

©2011 by The Royal Society

Page 7: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

Dependence of the power spectral density of the ECoG on the strength of specific connectivity .

I. Bojak et al. Phil. Trans. R. Soc. A 2011;369:3785-3801

©2011 by The Royal Society

Page 8: Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes

Predictions of (a) scalp EEG, (b) ECoG and (c) fMRI BOLD for different strengths of specific connectivity: 0% (top), 30%, 60%, 85% and 90% (bottom).

I. Bojak et al. Phil. Trans. R. Soc. A 2011;369:3785-3801

©2011 by The Royal Society