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  • Toxicologic and Exploratory Pathology Specialty Section (TEPSS)Our Goal: TEPSS aims to establish scientific and educational programs on current advances and policies regarding experimental pathology and to guide discussions of the application of pathology to regulatory policy and risk assessment. TEPSS also offers awards to deserving trainees and networking opportunities to the pathology community.

    Members include pathologists with a variety of backgrounds (DVM, MD, and/or PhD), biol-ogists and toxicologists who use pathology techniques, histologists, students and postdoc-toral trainees.

    For further information, contact a TEPSS officer: President: Glenn Cantor (glenn.cantor@bms.com)Vice President: Doug Wolf (wolf.doug@epamail.epa.gov)Vice President-Elect: Norman Barlow (norman.barlow@sanofi-aventis.com)Secretary / Treasurer: Tomas Magee (tom.magee@genzyme.com)Past-President: Charles Qualls (cquallsj@amgen.com)2nd Year Councilor: Brian Day (dayb@njhealth.org)1st Year Councilor: Zaher Radi (zaher.radi@pfizer.com)PDA Representative: Chidozie Amuzie (amuziec@dcpah.msu.edu) SAC Representative: Lu Wang (lwang3@u.washington.edu)

    Toxicological Sciences 10 Most Cited Articles With Pathological Endpoints

    1. Akiko Enomoto et al, (2001) High Sensitivity of Nrf2 Knockout Mice to Acetaminophen Hepatotoxicity Associated with Decreased Expression of ARE-Regulated Drug Metabo-lizing Enzymes and Antioxidant Genes. 59(1):169-177

    2. Louise G. Park et al, (2000) The Plasticizer Diethylhexyl Phthalate Induces Malforma-tions by Decreasing Fetal Testosterone Synthesis during Sexual Differentiation in the Male Rat. 58(2):339-349

    3. L. Earl Gray, Jr., et al, (2000) Perinatal Exposure to the Phthalates DEHP, BBP, and DINP, but Not DEP, DMP, or DOTP, Alters Sexual Differentiation of the Male Rat. 58(2):350-365

    4. Eve Mylchreest et al, (1998) Male Reproductive Tract Malformations in Rats Follow-ing Gestational and Lactational Exposure to Di(n-butyl) Phthalate: An Antiandrogenic Mechanism? 43(1):47-60

    5. Chiu-Wing Lam et al, (2004) Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation. 77(1):126-134

    6. Hisham K. Hamadeh et al, (2002) Gene Expression Analysis Reveals Chemical-Specific Profiles. 67(2):219-231

    7. Eve Mylchreest et al, (2000) Dose-Dependent Alterations in Androgen-Regulated Male Reproductive Development in Rats Exposed to Di(n-butyl) Phthalate During Late Ges-tation. 55(1):143-151

    8. D. B. Warheit et al, (2004) Comparative Pulmonary Toxicity Assessment of Single-wall Carbon Nanotubes in Rats. 77(1):117-125

    9. Hartmut Jaeschke et al, (2002) Mechanisms of Hepatotoxicity. 65(2):166-176

    10. Valerie D. Shultz et al, (2001) Altered Gene Profiles in Fetal Rat Testes afterin Utero Ex-posure to Di(n-butyl) Phthalate. 64(2):233-242

    TEPSS Awards

    Roger O. McClellan Student AwardThis award is made possible by the Roger O. McClellan Student Award Fund of the SOT Endowment. Special consideration will be given to abstracts that exemplify the role of comparative medicine in evaluating the safety/risk of exposure to chemicals or physical agents. Nominees for the Award must be individuals who are enrolled in a program lead-ing to a DVM degree or in post-DVM residency or graduate program. The awardee must be a member of the Society of Toxicology (any level) or have an application pending. The ab-stract must be submitted and accepted through the regular SOT submission process. This research must be hypothesis driven.

    Travel AwardsNominees must be the first author of an SOT-accepted abstract concerning research in toxicology that presents work illustrating the integrated application of pathology (morpho-logic or clinical pathology) endpoints with other scientific approaches, e.g. molecular or systems biology, imaging, or in vitro-in vivo correlations, to enhance the understanding of whole animal or tissue toxicologic responses.

    Charles Capen Student Travel Award This award is funded by the International Academy of Toxicologic Pathology recognizing Dr. Charles Capen and his legacy as a researcher, teacher, and mentor to the veterinary and toxicologic pathology communities spanning more than four decades. The successful applicant will have demonstrated achievements in the field of toxicologic pathology in-cluding but not limited to research contributing to public safety as it relates to the adverse health effects of xenobiotics, establishing test methods and standards that enhance the field of toxicologic pathology; and/or developing new or novel uses of toxicologic pathol-ogy in safety research.

    TEPSS Travel AwardThis award is sponsored by the Toxicologic and Exploratory Pathology Specialty Section membership. Abstracts will be judged based on scientific merit and clarity of presentation. Consideration will also be given to candidates whose professional goals include the incor-poration of the science of pathology in their research work

    Dr. James A. Popp (TEPSS member)SOT President 2006-2007

    A caricature of Dr. Wanda M. Haschek, co-author of Fundamentals of Toxicologic Pathology, rendered by Dr. Jack R. Harkema (TEPSS president, 2005-2006)

    Dr. Roger O. McClellan (TEPSS member)SOT President 1989-1990Arnold J. Lehman Award 1992Achievement award 2005Founders award 2009

    Above, Dr. Saini (right) winner of 2010 McClellan award and Dr. Barlow (TEPSS Vice-president elect

    Above, Dr. Liu (left) winner of 2010 Capen Awardand Dr. Qualls, Jr., TEPSS outgoing President

    Above, Ms Sparkenbaugh, winner of 2010 TEPSSStudent Travel Award, & Dr. Day, TEPSS Councilor

    1961 SOT founded 2001 TEPSS Founded 2011

    5%

    18%

    67%

    10%

    TEPSS Membership

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