#HIMSS21

Transforming Specialty Pharmacy to Deliver Better CareSession #116, August 11, 2021

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Chief Executive Officer, AllianceRx Walgreens Prime

Joel Wright, RPh

DISCLAIMER: The views and opinions expressed in this presentation are solely those of the author/presenter and do not necessarily represent any policy or position of HIMSS.

Chief Executive Officer and Chairman of the Board, Inovalon

Keith Dunleavy, MD

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Welcome

CEO and Chairman of the Board,Inovalon

Keith Dunleavy, MD

CEO, AllianceRx Walgreens Prime

Joel Wright, RPh

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Agenda

Introductions

Overview of Specialty Pharmacy and the Specialty Pharmacy Marketplace

Patient-Centric Specialty Pharmacy Management: AllianceRx Walgreens Prime

A Cloud-Based Platform Approach: Inovalon

Case Study: Real Time Data Stream and Insights for Better Patient Care and Experiences

Looking Ahead

Q & A

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Learning Objectives

1. Demonstrate how various segments of the healthcare ecosystem rely on the capabilities

of specialty pharmacy for their own respective care, quality, and economic goals

2. Analyze the steps taken to improve care and outcomes in specialty pharmacy

treatments

3. Evaluate the impact of advanced capabilities in connectivity and analytics on specialty

pharmacy operations

4. Illustrate how an expanded and shared view of patient-centric data can help healthcare

providers such as specialty pharmacies understand and improve the patient journey.

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What’s Special About Specialty Pharmacy?

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High-touch, high cost, & high complexity

Licensed, accredited pharmacy

providing medications for people with

chronic conditions or rare diseases,

requiring complex therapies

Patient-Centered Care and Disease ManagementDedicated assistance and support every

step of the way, including convenient

digital tools, medication services and

clinical support

Stakeholder Coordination and Management

Alignment across all disciplines, including

pharma, payer, provider, pharmacist

and patient

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Navigating Today’s Ever-Changing Market Dynamics

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Utilization

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Outdated and Legacy IT

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Technological Obstacles to Patient Care

Siloed PatientData

Time-lagged,Incomplete

Patient Information

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What is the problem we

are trying to solve?Current State of Healthcare in the U.S.

• Important patient data is scatteredacross silos – data that is needed by

providers, patients and payers isn’t

easily accessible

• Healthcare costs continue to rise

Future State of Healthcare in the U.S.• Data standards that make it easier to

transfer important data to the people who need it to care for patients

• Integrated data to streamline care

coordination

• Real time insights for informed decision

making at the point of care

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Uniting Clinical Expertise and Data

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Integrated pharmacy model with

Walgreens delivers total patient

experience with a single view

Data supplementation to identify and

address gaps in patient care

Technological investments to improve

clinical care and stakeholder access to

analytics

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Comprehensive and Proven Clinical Programs

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Innovative technology adapts clinical

assessment questions in real time based on

patient variables, driving stronger adherence and

outcomes.

Disease-focused teams comprised of dedicated, multidisciplinary specialists

apply a tailored approach to patient

needs.

Partner access to self-service portal with real-time actionable data

show trends in their patient population

Connected Care Specialty360 Therapy Teams Clinical Data and Reporting

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• Providing insights to help optimize

patient outcomes and total cost of

care

• Innovating to provide members

with an enhanced specialty

experience

Payer

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• Connecting patients to therapies

through market-leading access to

specialty medication

• Reducing administrative burden

and patient time-to-therapy

Provider

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• Utilizing unique pharmacy model to

start patients on therapy quickly

• Co-creating clinical and digital

offerings to improve adherence an

outcomes

Pharma

Connecting Across the Healthcare Ecosystem to Care for Specialty Patients

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Building an Enhanced Specialty Experience

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Email notifications

Online refills

Text notifications

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Inovalon Empowers Data-Driven Healthcare at Scale

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336M+ Patients

76K+ Provider Sites

100sHealth Plans, Providers, Life Sciences, Pharmacy, and Diagnostics Organizations

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Payers ProvidersLife Sciences

Companies

Pharmacy Organizations

Patient Engagement

Risk Score Accuracy

Patient Outcomes

Financial Performance

Clinical Operational Efficiency

Administrative Improvement

Patient Outcomes

Provider Engagement

Reduce Operational Costs

Improve Patient Care

AutomateReferrals

Streamline Order Workflow

Medical Claims Processing

Patient Outcomes

Optimal Treatment Protocols

Outcomes-Based Contracting

Health Economics and Outcomes

Research

Commercialization Strategies

MarketAccess

Payer Operations

Operational Transparency

Clinical Quality Metrics

Quality of Care

Point-of-Care Analytics

Serving the Needs of the Healthcare Ecosystem

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Leading Customer Presence Across Verticals

Top 25 U.S.

Health Plans

Top 25 U.S.

Provider Systems

Top 25 Global

Pharma Companies

Top 10 Pharmacy

Companies

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of 252

25

of 251

25

of 253 4

2

of 105

Top 10 Consumer

Retail Companies

7of 10⁴

1) Top 25 health plans based on AIS 2019 directory and CMS data; 2) Total Provider sites of care as of September 2019 based on CMS data; 3) Top 25 pharma companies based on PharmExec’s Top 50 Companies 2020; 4) Based on estimated pharma and life sciences companies' database; 5) Top national retailers based on National Retail Federation 2020 rankings.

Reflecting Inovalon’s differentiated capabilities, the Company’s significant customer base includes all 25 of the Top

25 health plans by size in the nation, all 25 of the Top 25 global pharma companies, 24 of the Top 25 healthcare

provider systems, and more than 76,000 U.S. provider sites.

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The Inovalon ONE® PlatformThe Inovalon ONE® PlatformIntegrated, real-time cloud platform delivering healthcare ecosystem connectivity,

multi-sourced big data assets, advanced analytics, and data-driven intervention toolsets.

Clients/Partners

Data Exchange

ApplicationConnectivity

Interactive Connectivity

API Gateway

Inovalon & Commercial Cloud

Shared ServicesData Aggregation and Access

Payer Applications

Provider Applications

Pharmacy Applications

Life SciencesApplications

Data Analytics(Traditional Methodologies, Machine Learning, Artificial Intelligence, Deep Learning)

• Diagnosis, lab, procedure, and pharmacy claims

• Electronic Health Record (EHR) clinical data

• Patient-reported data• Demographic data• Socioeconomic data

• Eligibility and Enrollment data

• DME usage data• Lab results data• Provider data• Facility census

and staffing data• Cost data

The MORE2 Registry®• 338M Unique Patients• 63B Medical Events• 1M+ Physicians• 584,000 Clinical Facilities

Customer-Specific Data StoresiPORT HD™

ConsumerApplications

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Connected Data Delivering Real Time Insights

Nationwide Connectivity

Primary-Sourced Healthcare Data

1000+ Active Connections

Multi-Sourced Data Inputs

1,100 Data Integrity Checks

Personalized care and experiences informed by data curated from

longitudinal health history

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ScriptMed® CloudA Configuration of the Inovalon ONE® Platform

Order

Fulfillment

Technicians

Specialty

Pharmacies

Physicians &

Practice Groups Nurses

Order

Management

Referral

Management

Clinical Care

Management

Revenue Cycle

Management

Contract

Management

MORE2 Registry® Analytics

ScriptMed®

Cloud Users

Inventory

Management

Patients

Connected

Parties

Health Plans

Hospitals &

Health Systems

Data

Supplementation

HUB

Pharmaceutical

& Suppliers

Diagnostic

Platforms

Laboratory

Systems

EHRs & HIEs

Reporting &

Visualization

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A Case Study

Enabling Real-Time Specialty Pharmacy forBetter Outcomes, Experience, and Business Performance

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• CA is a 53-year-old female• Diagnosed with rheumatoid arthritis• CA was initiated on methotrexate 7.5 mg• by mouth weekly• CA reported no improvement after three

months• The rheumatologist discontinued the

methotrexate and added a TNF-α inhibitor to CA’s therapy regimen

CA’s new prescription is sent to

AllianceRx Walgreens Prime:

•Cimzia® 200mg subcutaneously

every other week

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Typical Patient History Data Sources

PatientSelf-Reporting

FaxMachine

PhoneCalls

Hypertension, diagnosed in 2011

Hypercholesterolemia, diagnosed in 2010

Depression, diagnosed in 2003

Lisinopril 10mg daily

Atorvastatin 20mg daily

Multivitamin daily

Ibuprofen 600mg TID prn

Roadblocks to Timely, Patient-Centric Care

Data inaccuracy and

potential re-work

Lack of consistent data

standardization

Incomplete patient history and

information

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Inovalon DataStream® API Marketplace™

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Data Analytics(Traditional Methodologies, Machine Learning, Artificial Intelligence, Deep Learning

State HIE City HIE Cloud-

Based EHR

Hospital EHR

National

Payer

Regional

Payer

Local

Payer

Local

Payer

Practice

Group EHR

Authorized Third-Party Apps Serving

Consumers

CDEaaS™

Consumer

Health Gateway

API

Gateway

Data LakeIntegrate, Aggregate, Normalize, Transform)

The MORE2 Registry®

• 336M Unique Patients

• 62B Medical Events• 1M Physicians

• 580,000 Clinical Facilities

Shared Services

Custom-Specific Data Stores

iPORT HD™

The Inovalon DataStream API Marketplace™

Data Aggregation &

Access

Develop healthcare applications that enable you to solve problems today and innovate toward the future. Access FHIR-

enabled, purpose-built APIs that optimize value from data with insights from longitudinal clinically relevant patient

history.

Bi-DirectionalData Exchange

The Inovalon ONE Platform™

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Streamlined Data Experience, Curated Insights

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Social Determinantsof Health

MORE2

Registry®

Claims, Membership

& Provider Data

Structured & Unstructured Clinical EHR Data

PredictiveStatistical modeling and forecasting for prospective insights.

DescriptiveData aggregation

and mining for retrospective insights.

Prescriptive Optimization and

simulation algorithms to generate

recommendations for optimal actions.

Dashboards APIsSystem

Integration

Health Systems&

Clinics

Providers Payers Pharma

336M+

Patients

62B+

Medical Events750,000+ Connected

Providers> 1,200 Analytic Measure

Catalogs

Flexible ConsumptionAdvanced AnalyticsMultiple Data Inputs

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Patient-Level Data and Insights Streamed Incrementally

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Medications

Conditions

Allergies

Visits

Patient DetailPatient Summary

Care Timeline

Worklist

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• CW is a 44-year-old female• Diagnosed with multiple sclerosis• Initiated treatment with Tecfidera• Now being evaluated as part of her

Tecfidera refill protocol

CW’s refill prescription is sent to

AllianceRx Walgreens Prime:

• Tecfidera 240 mg PO BID

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FHIR-Enabled Patient Data Enrichment

PATIENT-REPORTED SAMPLE POST-ANALYTICS

Key:

Patient-Reported

EHR clinical data

MORE2 Registry

ScriptMed® CloudA Configuration of the

Inovalon ONE® Platform

Advanced

AnalyticsEHR Clinical

Data Integration

MORE2

Registry®

DataStream™ Patient History Enrichment

• Multiple Sclerosis

diagnosed in 2018

• Diabetes Mellitus Type

2 diagnosed in 2012

• Tecfidera

• Metformin

• Multiple Sclerosis: last evaluated

8/10/20

• Metformin 500 mg: last filled 1/20/21

***poor adherence

• Prednisone 20 mg: last filed 5/30/21

***significant corticosteroid usage

• 221 pounds weight: 5/10/21 (most

recent) ***significant weight gain

• Hemoglobin A1C Elevated: 5/10/20

***overdue for A1c and elevated

***concern for diabetes progression

• Eye Exam 2/1/18 *overdue for eye

exam

• Speed – Analytics identified medication non-adherence for diabetes

• Safety - Prompted screening

assessment for worsening of multiple sclerosis symptoms based on increased prednisone consumption

• Quality – Diabetes care alertsinformed pharmacist that patient needed counseling for A1c and diabetic eye exam)

• Efficiency – Visit dates made provider aware that patient had not seen her neurologist in ~ 1 year, prompting counseling to make an appointment for new medication evaluation

Real-Time Impact

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The Value of Real Time Data Delivery

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1 Access to clinical data – doctor visits

Access to lab data – liver function

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Access to billing/insurance info expedites

medication and prior authorization process

Access to patient’s pharmacy records

enables understanding of past RA

medications versus other medications

Personalized patient experience – delights

with comprehensive understanding of her

health history and current issues

Efficiency gains for the healthcare system –

decreased provider abrasion, streamlined

operations, etc.

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The Next Frontier for DataStream™ and Specialty Pharmacy

The next frontier is here

Performance Tracking and Monitoring

Enriched Data Elements

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Thank you!

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Questions

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