transgenic animalsftp.tugraz.at/pub/molekulare_biotechnologie/mol_911 molecular... · transgenic...
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Transgenic Animals
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Transgenic Animals
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Transgenic Animals
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Transgenic Animals
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Transgenic Animals
“Cloning”
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Transgenic Animals
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Transgenic Animals
Tissue specific Expression
CFTR: Cystic Fibrosis Transmembrane Conductance Regulator
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Transgenic Animals
Tissue specific Expression
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Transgenic animals as organ supplier
Immunological Barriers
Hyperacute rejectionAcute vascular rejectionCellular rejectionChronic rejection
Porcine endogenous retroviruses
Humanizing the pig:
Introduction of Human Genes
Knock out of pig genes -1.3 galactosyltransferase avoid immunogenic reaction
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