tryton - addressing the challenge of bifurcation stenting | dean j. kereiakes, m.d
TRANSCRIPT
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Tryton: Addressing the Challenge of Bifurcation Stenting
Dean J. Kereiakes, M.D.Medical Director, The Christ Hospital Heart and Vascular Center and the Lindner Research Center , Cincinnati, OhioProfessor of Medicine, Ohio State University
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• Modest Consulting Fees• Significant Consulting Fees• Significant Consulting Fees• Significant Consulting Fees• Significant Consulting Fees• Significant Consulting Fees• Major Stock Shareholder/Equity
• HCRI• Boston Scientific• Abbott Vascular• Svelte Medical Systems, Inc.• Janssen Research & Development LLC• Sanofi-Aventis U.S. LLC• Ablative Solutions, Inc.
Affiliation/Financial Relationship Company
Disclosure Statement of Financial InterestWithin the past 12 months, I or my spouse/partner have had a financial interest/arrangement or affiliation with the organization(s) listed below.
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Tryton-The Vision: To treat spectrum of Bifurcation Lesions with the Same
Predictability and Durability as Straight Lesions
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Bifurcation Lesions• Bifurcation lesions are characterized by
variable and complex anatomy:
FocalDiffuse Angulated
Calcified
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Clinical Segmentation- Plaque Distribution Classifications -
Duke Plaque Distribution Classification -
Type F:Pre-Branch & Ostial
Type A:Pre-Branch
(ICPS Type 3)
Type B:Post-Branch
(ICPS Type 4a)
Type C:Parent Vessel Only
(ICPS Type 2)
Type D:Bifurcation
(ICPS Type 1)
Type E:Ostial
(ICPS Type 4b)
Sources: Popma 1994; Baim TCT 2003
TrueBifurcation
ICPS
*
*
Bifurcation Disease Strategy, Morice, TCT 2005
*
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Bifurcation Stenting Techniques with Workhorse Stents
T Stenting V Stenting Y Stenting Culotte * Crush*
Kissing Stent* *”gap” coverage
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Complex Bifurcation Disease:Addressing with workhorse DES makes one ‘MADS’!
Catheter and Cardio Interventions 71:175–183 (2008)
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Unstented Vessel area versus Bifurcation angle
0
5
10
15
20
25
30
35
0 10 20 30 40 50 60 70 80 90
Bifurcation Angle (degrees)
Uns
tent
ed v
esse
l are
a (m
m^2
)
As bifurcation angle changes from 90º, unstented vessel area
increases rapidly with “workhorse stents”
Suboptimal Coverage & Drug delivery with Workhorse Stents
0 10 20 30 40 50 60 70 80 .
Bifurcation Angle (degrees)
UnstentedVessel Area
90
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Tryton Side Branch Stent
Transition Zone
Side Branch Zone
Main Branch Zone
8 mm 4.5 mm 6.5 mm
For Investigational Use Only in the United States For Investigational Use Only in the United States
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Tryton Deployed - Side Branch Secured
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Position Main Branch Stent
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Complete Lesion Coverage
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Tryton Sidebranch Stent
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Symposium Agenda
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Thank You