u41: research resource for image guided therapy

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U41: Research resource for Image guided therapy. PI: Ferenc Jolesz. U41 Image guided therapy. Background & Significance IGT technology growth Clinical imaging growth Aim Advance and propagate novel image guided procedures - PowerPoint PPT Presentation

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Department of Radiology, BWHSlide *
PI: Ferenc Jolesz
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Advance and propagate novel image guided procedures
To dev and implement IGT technologies and allow rapid deployment in clinic
©2005 Surgical Planning Laboratory, ARR
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Leader: Alex Golby
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Continuous activities on site
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Collaborations
Technology based
Advancing imaging and image processing into the OR of the future
AMIGO
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Internal (11) NIH funded grants
d2.1 G CT R01 AG 19513 MR guided prostate diagnosis and brachytherapy
External (8) NIH grants with BWH collaborators
d2.1p Christos Davatzikos 1R01 CA 104976 Targeted prostate biopsy using mathematical optimization
©2005 Surgical Planning Laboratory, ARR
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GE
Doumoulin/Pelc
3 projects stem from the Engineering research center for computed surgical systems and technology (CISST ERC)of Johns Hopkins
Targeted biopsy (Christos Davatzikos)
Transrectal prostate therapy robot in closed MRI scanner (Gabor Fichtinger)
©2005 Surgical Planning Laboratory, ARR
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An example
Prostate intervention
Paradigm shift
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Infrastructure
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left
right
Probability of cancer occurrence shown in green (left) and its
adaptation (middle) to a stack of segmented intra-operative MR images obtained at the BWH (right). Optimal biopsy sites are transferred to the patient's space.
©2005 Surgical Planning Laboratory, ARR
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IGT Procedural
Staple-analysis of expert and automated methods
Procedure Feasibility
Patient safety, toxicity profiles, Cancer control-long and short term outcomes
©2005 Surgical Planning Laboratory, ARR
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©2005 Surgical Planning Laboratory, ARR
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1.                  Tempany CMC, McNeil BJ. Advances in biomedical imaging. JAMA 2000; 285(5):562-567.
Apex
Base
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Anterior
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Apex
Base
Posterior
Anterior
Left
Right
6
7
4
3
1
2
5