ultrasonographic lung sliding sign in confirming proper endotracheal intubation during emergency...

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study specifically were blunt trauma, injury to the brain, and transfer from or referral to a non-TARN hospital. Regression analyses were performed crude and adjusted for age, gender, In- jury Severity Scale, and Glasgow Coma Scale score. Using data from January 2000 through December 2009, a total of 3444 pa- tients from 161 hospitals, with a median age of 30.0 years and SBP of 126 mm Hg, were analyzed. The majority of patients (86.9%) were male. Mortality ranged from 1.2% in patients with an SBP $ 170 mm Hg to 47.7% in patients with SBP < 70 mm Hg (p for linear trend < 0.001). After adjustment for confounders, mortality odds doubled at 90–109 mm Hg (odds ratio [OR] 2.22, 95% confidence interval [CI] 1.09– 4.50) compared to the reference range of 110–129 mm Hg. Odds were four-fold higher at 70–89 mm Hg (OR 4.01, 95% CI 2.02–7.95), 10-fold higher at < 70 mm Hg (OR 10.3, 95% CI 4.76–22.2), and unchanged for SBP 150–169 mm Hg (OR 0.65, 95% CI 0.22–1.91) or SBP $ 1700 mm Hg (OR 0.20, 95% CI 0.03–1.17). [Omeed Saghafi, MD Denver Health Medical Center, Denver, CO] Comment: This study was limited principally by its retro- spective design. It also has questionable generalizability, given the composition of the patient population within the study group. Nonetheless, the finding that mortality increases at a blood pressure cutoff of 110 mm Hg is of interest, as this is higher than most Emergency Physicians would traditionally as- sociate with such an adverse outcome. Additional research with blunt and more minor trauma would be of special interest, espe- cially if it corroborated this finding. , PREVALENCE AND INCIDENCE OF LONGER TERM PAIN IN SURVIVORS OF POLYTRAUMA. Gross T, Amsler F. Surgery 2011;150:985–95. This study sought to better define the prevalence and severity of chronic pain in patients who have suffered polytrauma, and to evaluate the utility of different methods of measuring pain in these patients. The authors identified 229 consecutive patients over 4 years who were treated for blunt polytrauma at an aca- demic trauma center in Switzerland. Patients were included if at least two Abbreviated Injury Severity regions were affected and the patient had an Injury Severity Score of > 16. Follow- up data were collected by mail surveys at a mean of 2.4 years after injury. However, 23% of patients were not alive at the time of follow-up, and 43% did not respond. The final cohort in- cluded 102 polytrauma survivors. Patients were asked to rate their pre-injury pain and quality of life as well as post-injury pain, quality of life, and functional outcomes using seven previ- ously described scoring systems. At the time of follow-up, 54% of patients were fully rehabilitated. The prevalence and severity of pain differed among the different pain score metrics used, but overall, the authors found that 46–85% of patients reported pain that they did not have before injury, and the different scores used in the assessment of longer-term pain correlated well (R = 0.4– 0.9). The authors found that the Trauma Outcome Profile (TOP), a recently developed scoring system, was the most sensitive for incidence of pain, and correlated best with objective functional outcomes. Several factors were found to be associated with prevalence of long-term pain in polytrauma survivors, including higher initial Trauma and Injury Severity Score, and blue-collar profession. Increased severity of long-term pain was associated with existence of pre-injury pain, lesser pre-injury quality of life, and lower educational level. [Nir Harish, MD Denver Health Medical Center, Denver, CO] Comments: This study had several significant limitations, in- cluding a low follow-up rate, potential for significant recall bias in patient assessment of pre-injury pain, and reliance on subjec- tive outcome data. It is also unclear if the length of follow-up was sufficient, given that only 54% of patients were considered fully rehabilitated at the time of follow-up. Some confounding factors that have been previously described, such as the effect of traumatic brain injury on chronic pain, were not addressed. Nonetheless, the results highlight the heavy disease burden of chronic pain in survivors of polytrauma. The role of the TOP score for evaluation of chronic pain in survivors of trauma will need to be studied further, but may prove to be a useful tool. , ULTRASONOGRAPHIC LUNG SLIDING SIGN IN CONFIRMING PROPER ENDOTRACHEAL IN- TUBATION DURING EMERGENCY INTUBATION. Sim SS, Liena WC, Chou HC, et al. Resuscitation 2012;83:307–12. Unrecognized single-lung intubation can lead to hypoventi- lation, atelectasis, barotrauma, and even patient death. This pro- spective, single-center, observational study conducted at the Emergency Department of a national university teaching hospi- tal in Taiwan aimed to assess the utility of ultrasound lung slid- ing sign in confirming proper endotracheal tube placement during emergency intubation, as previous cadaver studies have noted the absence of lung sliding in some cases of one-lung in- tubation. One hundred fifteen emergent intubations were in- cluded; 9 (7.8%) had one-lung intubations by chest radiograph. The overall accuracy of ultrasound to confirm proper endotracheal intubation was 88.7% (95% confidence in- terval [CI] 81.6–93.3%). The positive predictive value was 94.7% (95% CI 87.1–97.9%) in the non-cardiac-arrest group and 100% (95% CI 87.1–100.0%) in the cardiac-arrest group. Hence, unilateral absence of lung sliding is not accurate enough to detect one-lung intubation. However, this study produced re- sults that corroborate the findings of previous studies, and further support the practice of using bilateral lung sliding in identifying proper endotracheal tube placement, especially in cardiac arrest patients. Moreover, the median operating time of ultrasound was 88 s (interquartile range [IQR] 55.0–193.0), and of chest radiog- raphy was 1349 s (IQR 879.0–2221.0) post intubation. [Douglas Melzer, MD Denver Health Medical Center, Denver, CO] Comments: The principal limitation of this study was its very small size and exceedingly small number of true positives. The results of the study would not seem to support the enthusiasm of the authors in advocating for this test, as chest X-ray study is clearly superior for detecting the rare single-lung intubation. The exception may be in cardiac arrest, although in that situa- tion, it is unclear whether making the determination using ultra- sound, although more rapid, will have any impact on clinical outcome. 752 Abstracts

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752 Abstracts

study specifically were blunt trauma, injury to the brain, andtransfer from or referral to a non-TARN hospital. Regressionanalyses were performed crude and adjusted for age, gender, In-jury Severity Scale, and Glasgow Coma Scale score. Using datafrom January 2000 through December 2009, a total of 3444 pa-tients from 161 hospitals, with a median age of 30.0 years andSBP of 126 mm Hg, were analyzed. The majority of patients(86.9%) were male. Mortality ranged from 1.2% in patientswith an SBP$ 170 mm Hg to 47.7% in patients withSBP < 70 mm Hg (p for linear trend < 0.001). After adjustmentfor confounders, mortality odds doubled at 90–109 mm Hg(odds ratio [OR] 2.22, 95% confidence interval [CI] 1.09–4.50) compared to the reference range of 110–129 mm Hg.Odds were four-fold higher at 70–89 mm Hg (OR 4.01, 95%CI 2.02–7.95), 10-fold higher at < 70 mm Hg (OR 10.3, 95%CI 4.76–22.2), and unchanged for SBP 150–169 mm Hg (OR0.65, 95% CI 0.22–1.91) or SBP$ 1700 mm Hg (OR 0.20,95% CI 0.03–1.17).

[Omeed Saghafi, MD

Denver Health Medical Center, Denver, CO]

Comment: This study was limited principally by its retro-spective design. It also has questionable generalizability, giventhe composition of the patient population within the studygroup. Nonetheless, the finding that mortality increases ata blood pressure cutoff of 110 mm Hg is of interest, as this ishigher than most Emergency Physicians would traditionally as-sociate with such an adverse outcome. Additional research withblunt and more minor trauma would be of special interest, espe-cially if it corroborated this finding.

, PREVALENCE AND INCIDENCE OF LONGERTERMPAIN INSURVIVORSOFPOLYTRAUMA.Gross T,Amsler F. Surgery 2011;150:985–95.

This study sought to better define the prevalence and severityof chronic pain in patients who have suffered polytrauma, and toevaluate the utility of different methods of measuring pain inthese patients. The authors identified 229 consecutive patientsover 4 years who were treated for blunt polytrauma at an aca-demic trauma center in Switzerland. Patients were included ifat least two Abbreviated Injury Severity regions were affectedand the patient had an Injury Severity Score of > 16. Follow-up data were collected by mail surveys at a mean of 2.4 yearsafter injury. However, 23% of patients were not alive at thetime of follow-up, and 43% did not respond. The final cohort in-cluded 102 polytrauma survivors. Patients were asked to ratetheir pre-injury pain and quality of life as well as post-injurypain, quality of life, and functional outcomes using seven previ-ously described scoring systems. At the time of follow-up, 54%of patients were fully rehabilitated. The prevalence and severityof pain differed among the different pain score metrics used, butoverall, the authors found that 46–85% of patients reported painthat they did not have before injury, and the different scores usedin the assessment of longer-term pain correlated well (R = 0.4–0.9). The authors found that the Trauma Outcome Profile (TOP),a recently developed scoring system, was the most sensitive forincidence of pain, and correlated best with objective functionaloutcomes. Several factors were found to be associated withprevalence of long-term pain in polytrauma survivors, including

higher initial Trauma and Injury Severity Score, and blue-collarprofession. Increased severity of long-term pain was associatedwith existence of pre-injury pain, lesser pre-injury quality oflife, and lower educational level.

[Nir Harish, MD

Denver Health Medical Center, Denver, CO]

Comments: This study had several significant limitations, in-cluding a low follow-up rate, potential for significant recall biasin patient assessment of pre-injury pain, and reliance on subjec-tive outcome data. It is also unclear if the length of follow-upwas sufficient, given that only 54% of patients were consideredfully rehabilitated at the time of follow-up. Some confoundingfactors that have been previously described, such as the effectof traumatic brain injury on chronic pain, were not addressed.Nonetheless, the results highlight the heavy disease burden ofchronic pain in survivors of polytrauma. The role of the TOPscore for evaluation of chronic pain in survivors of traumawill need to be studied further, but may prove to be a useful tool.

, ULTRASONOGRAPHIC LUNG SLIDING SIGN INCONFIRMING PROPER ENDOTRACHEAL IN-TUBATION DURING EMERGENCY INTUBATION. SimSS, Liena WC, Chou HC, et al. Resuscitation 2012;83:307–12.

Unrecognized single-lung intubation can lead to hypoventi-lation, atelectasis, barotrauma, and even patient death. This pro-spective, single-center, observational study conducted at theEmergency Department of a national university teaching hospi-tal in Taiwan aimed to assess the utility of ultrasound lung slid-ing sign in confirming proper endotracheal tube placementduring emergency intubation, as previous cadaver studies havenoted the absence of lung sliding in some cases of one-lung in-tubation. One hundred fifteen emergent intubations were in-cluded; 9 (7.8%) had one-lung intubations by chestradiograph. The overall accuracy of ultrasound to confirmproper endotracheal intubation was 88.7% (95% confidence in-terval [CI] 81.6–93.3%). The positive predictive value was94.7% (95% CI 87.1–97.9%) in the non-cardiac-arrest groupand 100% (95% CI 87.1–100.0%) in the cardiac-arrest group.Hence, unilateral absence of lung sliding is not accurate enoughto detect one-lung intubation. However, this study produced re-sults that corroborate the findings of previous studies, and furthersupport the practice of using bilateral lung sliding in identifyingproper endotracheal tube placement, especially in cardiac arrestpatients. Moreover, themedian operating time of ultrasoundwas88 s (interquartile range [IQR] 55.0–193.0), and of chest radiog-raphy was 1349 s (IQR 879.0–2221.0) post intubation.

[Douglas Melzer, MD

Denver Health Medical Center, Denver, CO]

Comments: The principal limitation of this study was its verysmall size and exceedingly small number of true positives. Theresults of the study would not seem to support the enthusiasm ofthe authors in advocating for this test, as chest X-ray study isclearly superior for detecting the rare single-lung intubation.The exception may be in cardiac arrest, although in that situa-tion, it is unclear whether making the determination using ultra-sound, although more rapid, will have any impact on clinicaloutcome.