university of birmingham business club breakfast briefing...tuesday 10 october 2017 university of...
TRANSCRIPT
![Page 1: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/1.jpg)
Tuesday 10 October 2017
University of Birmingham Business Club
Breakfast Briefing
‘Innovative surface
coatings and food
hygiene’
![Page 2: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/2.jpg)
Innovative Surface
Coatings & Hygiene
Dr Zhenyu Jason Zhang School of Chemical Engineering
University of Birmingham
![Page 3: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/3.jpg)
Outline
Overview
Surface coating strategies
Antimicrobial surface coating
Our approaches
– Design
– Testing
![Page 4: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/4.jpg)
What I am interested
![Page 5: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/5.jpg)
Why am I interested in
• Surface functionalization /
coating
• Colloidal stabilization
• Lubrication
• Detergents
• Fouling/Cleaning
Soft matter at surface/interface
• Biomaterials
• Drug delivery
• Cell mechanics
• etc.
![Page 6: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/6.jpg)
Surface coating strategies
Substrate
Surface coating
Surface
Interface
Coating
• Vapour deposition
• Chemical & electrochemical route
• Spraying
• Roller coating
• Physical coating
![Page 7: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/7.jpg)
Antimicrobial surface coating
Implications in medical applications:
• Biofilm infection
• Increased resistance to antimicrobial
therapy and immune clearance
• Limiting treatment options
• Life threatening disease
• Medical device
• Consumer goods
• Food packaging
![Page 8: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/8.jpg)
Development - concept
• Two major strategies
• Anti-adhesive: polymer, hydrogel, superhydrophobic
• Bactericide: antimicrobial peptides, antibiotics, chitosan, enzymes
• Multi-functional coating
• Application dependent
• Expectation
![Page 9: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/9.jpg)
Surface modification – chemical
routes • Polyelectrolyte layer
• Inorganic film
![Page 10: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/10.jpg)
Surface modification – physical routes
• Organic film
• Precision machining
![Page 11: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/11.jpg)
Testing – initial stage Protein adsorption • Adsorption kinetics
• Adsorption amount
• Distribution on surfaces
• Response to environment
• Removal force required
![Page 12: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/12.jpg)
Testing – individual cell
Escherichia coli
Pseudomonas putida
![Page 13: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/13.jpg)
Testing - biofilm
Rhodococcus sp. Enterococcus faecalis
![Page 14: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/14.jpg)
Thank you!
![Page 15: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/15.jpg)
And now Pitches
![Page 16: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/16.jpg)
N troPep
Dr Felicity de Cogan Royal Academy of Engineering Enterprise Fellowship
Institute of Microbiology and Infection [email protected]
@FelicitydeCogan www.nitropep.com
@NitroPep
![Page 17: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/17.jpg)
N troPep
The Problem What is growing on the surfaces you touch everyday?
MRSA
Pseudomonas aeruginosa
Micrococcus
![Page 18: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/18.jpg)
The Solution • Durable, non-toxic and
efficacious.
• Significantly reduces bacteria number in laboratory tests.
• Greater than 99 % effective
in trials with potential customers
N troPep
![Page 19: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/19.jpg)
Trials
Queen Elizabeth Hospital Trial – NitroPep surface modification showed greater than 99 % efficacy
Control
NitroPep Surface
N troPep
![Page 20: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/20.jpg)
What We Need!
N troPep
Innovative companies who are looking for disruptive technologies in the
market
Sales representatives with expertise in the healthcare market,
especially the NHS.
![Page 21: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/21.jpg)
How to get in touch
N troPep
Dr Felicity de Cogan
07727611651
@FelicitydeCogan
![Page 22: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/22.jpg)
Next…
![Page 23: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/23.jpg)
Firm performance and wage setting
Anne Green Professor of Regional Economic Development
[email protected] 0121 414 9666
![Page 24: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/24.jpg)
Firm performance and wage setting Funded by the Joseph Rowntree Foundation City-REDI is investigating the hospitality, retail and manufacturing sectors with regard to the following:
Up to an hour of your time for a discussion Confidentiality and anonymity guaranteed
What this is for – Research to inform and influence policy
What metrics do you use to measure firm performance? What approaches are you using to increase productivity? What factors do you consider when setting wages? (How) do workers gain from productivity increases?
![Page 25: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/25.jpg)
Next…
![Page 26: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/26.jpg)
A.T.E.T.A Opportunities - Future Energy
Systems
David Terry Business Engagement Manager
[email protected] 07973 984485
![Page 27: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/27.jpg)
ATETA
What we do
Business support for energy technology companies and energy users
What we need
• Free service to all SME businesses in Birmingham, Bromsgrove, Cannock Chase, East Staffordshire, Lichfield, Redditch, Solihull Tamworth and Wyre Forest
What we offer
Multi disciplinary team – smart grid and electrical systems, thermal energy material and storage, bio-energy generation
Our USP
Take advantage of opportunities
in a changing energy market
place. Access expertise and
facilities in a World leading Energy
institute
![Page 28: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/28.jpg)
![Page 30: University of Birmingham Business Club Breakfast Briefing...Tuesday 10 October 2017 University of Birmingham Business Club Breakfast Briefing ‘Innovative surface coatings and food](https://reader033.vdocuments.net/reader033/viewer/2022051901/5ff0bbe105a95e08f20c15cf/html5/thumbnails/30.jpg)
Thank you to our
speakers and for
your attention