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Urinary System Drugs

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Common UrinaryAgents ProblemsUrecholine

Urispas

Urex/Hiprex

Pro-banthine

Pyridium (phenazopyridine)

Oxybutynin

Detrol

Increase peristalsis

Increase bladder capacity

Bactericidal

Bladder spasms

Local anesthetic ( Rx & OTC)

Urinary antispasmodic

Bladder control

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Diuretic Therapeutic Classes

Carbonic Anhydrase inhibitors

Osmotic

Loop

Thiazides

Combination

Potassium-Sparing

Miscellaneous

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Carbonic Anhydrase Osmotics

Acetazolamide (Diamox)

Loop furosemide (Lasix)

torsemide (Demadex)

bumetanide (Bumex)

Mannitol

ThiazidesHydrochlorothiazide

(HCTZ)

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Combination K+Sparing

Triamterene-HCTZ• Dyazide• Maxzide

Triamterene (Dyrenium)Spironolactone (Aldactone)

MiscellaneousIndapamide (Lozol)Metalazone (Zaroxolyn)

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Renal Function and DiseaseStages of Renal Disease Causes of Renal Failure

Loss of renal reserve

Renal insufficiency

Chronic renal failure

End stage renal disease

Pre-renal• Decreased volume to

kidneys

Intra-renal• Physical damage

• Toxins

Post-renal• Block urine flow

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Agents for Renal Disease

Epogen & Procrit (epoetin alfa {erythropoietin}

Folvite (folic acid {vitamin B9}

Nestrex (pyridoxine {vitamin B6}

Multiple vitamin complex (MVI)

InFed (iron dextran injection)

Renagel (Sevelamer)

Calciferol (ergocalciferol {Vitamin D})

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What are UTI’s?

Classification• Cystitis

• Urethritis (lower tract)

• Prostatitis

• Pyelonephritis (upper tract)

Treatment• Antibiotics (SMZ-TMP, Amoxil, Nitrofurantoin)

• Analgesics (phenazopyridine)

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Summary Slide

Renal Function and Disease

Agents for Renal Disease

Common Urinary Problems & Agents Benign Prostatic Hypertropy (BPH) in text

Anatomy of the Nephron

Diuretic Therapeutic Classes and MOA