transplanted without a history of renal cell carcinoma. These statistics are for individuals 65 yearsor older at the time of transplantation. Finally, the authors indicate that about one-fifth of patientshave recurrence of the renal cell carcinoma following transplantation.

W. Scott McDougal, M.D.

Is Preoperative Iodine 123 Meta-Iodobenzylguanidine Scintigraphy Routinely Necessary BeforeInitial Adrenalectomy for Pheochromocytoma?

J. MISKULIN, B. L. SHULKIN, G. M. DOHERTY, J. C. SISSON, R. E. BURNEY AND P. G. GAUGER, Departments ofSurgery and Radiology (Nuclear Medicine), University of Michigan, Ann Arbor, Michigan

Surgery, 134: 918–923, 2003

Background. Iodine 123 meta-iodobenzylguanidine (MIBG) scintigraphy has been used in patients withclinical suspicion of pheochromocytoma to confirm the nature of an adrenal or extraadrenal mass or toidentify occult disease. Additionally, it may be used to identify unsuspected bilaterality or metastases in thesetting of a known unilateral adrenal mass before operation. We sought to determine the role of 123I MIBGscintigraphy in this apparently routine preoperative setting. Our hypothesis was that 123I MIBG wouldprovide additional preoperative information that could modify operative intervention.Methods. All patients undergoing 123I MIBG scintigraphy at our institution between 1992 and 2002 were

identified. MIBG results, operative procedures and findings, and pathologic findings were retrospectivelyreviewed and compared.Results. The 123I MIBG scintigraphy was performed in a total of 315 patients. Of these, 48 were patients

with an initial biochemical diagnosis of pheochromocytoma and a unilateral adrenal mass. 47 of the 48(98%) primary scans were positive for a single focus of activity concordant with anatomic imaging data fromcomputed tomography or magnetic resonance imaging and operative findings. The 123I MIBG did not revealunsuspected metastatic or bilateral disease in any patient.Conclusion. In this large series of patients undergoing 123I MIBG scintigraphy, the test served only to confirm

diagnostic impressions and corroborate anatomic imaging. The 123IMIBGdid not alter the operativemanagement ofany patient with a solitary adrenal lesion in the clinical context of biochemically-proven catecholamine excess.

Editorial Comment: Simply put, MIBG studies did not reveal any unsuspected metastases orbilateral disease involvement in an analysis of more than 315 patients. Nor did it alter theoperative treatment of any patient with a solitary adrenal lesion. Thus, the bottom line is thatonly under highly selected circumstances is MIBG appropriate.

W. Scott McDougal, M.D.

Optimal Timing of Hydration to Erase Contrast-Associated Nephropathy: The OTHER CANStudy

R. A. KRASUSKI, B. M. BEARD, J. D. GEOGHAGAN, C. M. THOMPSON AND S. A. GUIDERA, Division of Cardiology,Wilford Hall Medical Center, Lackland Air Force Base, Texas

J Invasive Cardiol, 15: 699–702, 2003

Permission to Publish Abstract Not Granted

Editorial Comment: These authors studied contrast nephropathy in patients undergoingelective coronary artery catheterization. The use of contrast material in such patients hasrelevance to those of us who use it for renal imaging. The authors looked at 2 treatmentmodalities—overnight hydration and bolus administration—in patients with moderate renalinsufficiency before the study. They noted that 11% of patients in the bolus group versus nonein the overnight hydration group had an increase in serum creatinine of greater than 0.5 mg/dl.Although these results did not achieve statistical significance, it appears that in the high riskpatient overnight hydration would be preferable to bolus hydration.

W. Scott McDougal, M.D.

VOIDING FUNCTION AND DYSFUNCTION, BLADDER PHYSIOLOGY ANDPHARMACOLOGY, AND FEMALE UROLOGY

Urodynamics Prior to Prostatectomy: Pro

S. MADERSBACHER,Department of Urology and Ludwig Boltzmann Institute for Urological Oncology, Donaus-pital, Vienna, Austria

Eur Urol, 45: 557–560, 2004

No Abstract

VOIDING FUNCTION, BLADDER PHYSIOLOGY AND PHARMACOLOGY, AND FEMALE UROLOGY2492