Career trajectoriesUsing NIH grant data to understand the job paths of

biomedical researchers

Christopher L. Pickett, Ph.D.Director

Rescuing Biomedical Research1

79% 60%

10%

New Ph.D.s who do a postdoc

Sauermann and Roach, 2016

Postdocs who want a faculty position

Postdocs who get a faculty position

Attrition

FundingPublications

“I have to get my K99 before I can go on the job market!”

3

4

Perc

ent F

TR01

aw

arde

es w

ith N

IH tr

aini

ng a

war

d

With F or K award before R01

With no NIH award before R01

F32

K01

K08

K23

K99

NRSA postdoctoral fellowship

Research scientist CDA

Clinical scientist research CDA

Patient-oriented research CDA

Pathway to Independence

PhD, MD

PhD

MD

MD

PhD, MD

6

25

No preference

25

Q1, Q2 prefer

25

Q3, Q4 prefer

First Time R01 awards

25% 50% 75%12

institutions23

institutions46

institutions897

institutions

Quartile 4Quartile 2 Quartile 3Quartile 1

Stanford Dartmouth Princeton

Institutional preference for training awardees

7

F32 K01 K08 K23 K99 None

Perc

ent o

f FTR

01 a

war

dee

pool

1 2 3 4

What percentage of FTR01 awardees got their F/K at the same institution as their first R01?

8

Perc

ent s

tayi

ng a

t sam

e in

stitu

tion

Conte & Omary2018 J Clin Invest

Institutional preference for training awardees

9

F32 K01 K08 K23 K99 None

Perc

ent o

f FTR

01 a

war

dee

pool

1 2 3 4

10

0 – 15%

15 – 25%

25 – 35%

35 – 50%

>50%

0-3.75%

3.75-6.25%

6.25-8.75%

8.75-12.5%

>12.5%

110 – 15% 0-3.75% 15 – 25% 3.75-6.25% 25 – 35% 6.25-8.75% 35 – 50% 8.75-12.5% >50% >12.5%

12

(12 schools)

K99 awards

K99 institutions

R00 institutions

9%

39%

(405 awards) (145 schools)

64%

R00 conversion rate

*

13

White Multiracial Asian Black

*

**

Perc

ent

K99 success rate

14

• Better understand immigrant faculty, postdoc populations

• How do T trainees affect these values?

• What are the dynamics in retention versus external hiring?

• How do K awards factor into early lab funding?

• What can small groups of universities do to diversify the research enterprise?

• How well do other grant mechanisms support underrepresented scienitsts?

Thank you!

Chris Pickettclp3@princeton.edu

@ChrisPickett5