vaibhav[dengue fever]

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    ALL INDIA SENIOR SECONDARY CERTIFICATE

    EXAMINATION

    OF

    CENTRAL BOARD OF SECONDARY EDUCATION..

    NAME OF THE PROJECT : DENGUE FEVER .

    SUBJECT : BIOLOGY.

    SCHOOL : D.A.V. Sr. Sec. PUBLIC

    SCHOOL,BINA.

    SUBMITTED BY : VAIBHAV GUPTA.

    ROLL NO. :

    DATE OF SUBMISSION :

    GUIDE : Mrs. URMILA TRPATHI.

    Mr. A.K. SINGH. Mrs. URMILA

    TRIPATHI.

    [PRINCIPAL] [HEAD OF BIOLOGY

    DEPT.]

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    1. ACKNOWLWDGEMENT.

    2. PLANNING OF THE PROJECT.

    3. WHY A PROJECT?

    4. AIM OH THE PROJECT.

    5. WHAT IS DENGUE FEVER?

    6. INCIDENCE AND PREVELENCE.

    7. SYMPTOMS AND SIGNS.

    8. COMPLICATION OF DENGUE FEVER.

    9. DIAGNOSIS.

    10. TREATMENT OF DENGUE.

    11. PROGNOSIS OF DENGUE FEVER.

    12. PREVENTION OF MOSQUITO BITES.

    13. PREVENTION OF MOSQUITO BREEDING.

    14. REFRENCES.

    15. DECLARATIONS.

    16. CERTIFICATE.

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    ACKNOWLEDGEME

    NT.Acknowledgement is due to the principal Mr. A.K.

    Singh, DAV Sr. Sec. Public School, Bina for

    granting the necessary permission to write this

    project guidance to achieve the goal.

    I am very grateful to our Head of Biology

    Department Mrs. Urmila Tripathi for her kind co-operation and valuable suggestions provided to

    me in order to achieve my goal successfully by

    providing with certain information, which was of

    great help to me. This is her supervision and

    guidance that the project work has been taken

    up and completed.

    I must express extreme heartiest thanks towardsall the staff and attendants of Biology

    Laboratory, without the help of whom this work

    would have never been completed.

    I express my sincere thanks to my classmates for

    their valuable assistance and co-operation during

    the course of the project work.

    At last, I thank all those who directly or indirectly

    helped me in making and completing my project

    work on DENGUE FEVER.

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    NAME: VAIBHAV GUPTA.

    ROLL NO.:

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    PLANNING OF THE

    PROJECT.The very first discussion of carrying the project thrilled me

    a lot. I was rather excited to carry out the project as early

    as possible and circumstances allowed me. Now, the first

    thing I had to do was to search the project that could

    satisfy my expectations.

    I took help from:-

    ENCYCLOPEDIA- BRITANNICA.

    NEWSPAPAER- THE TIMES OF INDIA &

    HINDUSTAN TIMES. COMPUTER SOFTWARES.

    VAIBHAV GUPTA.

    CLASS- XII-B

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    WHY A PROJECT..

    The project method of learning is the best manner

    through which a student specially a science student apply

    the knowledge he gains from classroom lectures to daily

    life. One not only learns how to solve the problems but

    also starts taking interest in everything that he does in

    the laboratories.

    This method enables the student to understandsignificance and utilization of the subject n their daily life

    and allow them to choose their activities.

    A project is defined as, A whole hearted, purposeful

    activity that proceeds in a social environment. Thus,

    project is stated to be a piece of work in which a student

    does their own research and presents the results.

    By doing a project work a student displays their spirit

    of enquiry, a creativity of improving the existing method

    of solving a problem through understanding of the

    existing situation, independent thinking and ability to

    understand the basic facts. It also helps the student in the

    art of organizing, designing, planning to achieve a

    particular aim.

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    AIM OF THE PROJECT..The aim of this project is to get more knowledge about

    DENGUE FEVER and to understand its possible causes,

    symptoms, treatment etc.

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    WHAT IS DENGUEFEVER??Dengue is caused by four closely related but

    antigenitically distinct virus serotypes and transmitted

    from person to person by a bite from the mosquito,

    AEDES AEGYPTI.

    The

    first clinical

    report of

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    dengue was done by BENJAMIN RUSH in 1789. However its

    viral cause and its transmission via the mosquitoes were

    only established in early 20th century.

    Dengue and Dengue Hemorrhagic Fever [DHF] isa mosquito borne disease virus caused by the virus that

    belonged to the group of FLAVIVIRUS.

    Dengue viruses are transmitted from person

    to person by the bite from Aedes aegypti, a domestic

    mosquito.

    The disease is caused by any of the fourclosely related, but antigenitically distinct, virus serotypes

    DEN-1, DEN-2, DEN-3, AND DEN-4.

    Due to serotype specificity,

    infection caused by one serotype does not provide cross

    protective immunity to other serotypes, so a person is

    susceptible to have four dengue infections during their

    lifetime.

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    INCIDENCE AND

    PREVELENCE..

    The worldwide incidence is estimated to be 50 to 100

    million cases of dengue fever. And over 5,00,000 cases of

    dengue hemorrhagic fever per year..

    The incidence of this fever is variable and depends on

    the geographical region and the density of mosquito

    borne diseases in a region. DENGUE Hemorrhagic Fever is

    more serious and the fatality rate is about 5%.

    Children younger than 15 years comprise 90% of

    dengue hemorrhagic fever subjects in the world. Dengue

    Hemorrhagic Fever can affect both adults as well aschildrens.

    Poor surveillance system in India makes it

    difficult to know the exact incidence of the epidemic in

    the country. There have been reports regularly in medical

    literature from various hospitals. Between September

    2001 and January 2002, during the epidemic of dengue in

    Chennai, Tamil Nadu india nearly 800 cases were reported

    to the health system.

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    SYMPTOMS AND

    SIGNS..Abrupt fever, assosciated with headaches and pain

    that affects legs, joints, and the lumbar region of the

    spine are the classical symptoms of Dengue.

    Classic dengue is characterized by Fever :

    Sudden and abrupt onset.

    May go upto 39.5-41.4C.

    Last for about 1-7 days, then fades away for 1-2

    days.

    It soon reoccurs with secondary rashes which is

    usually not as severe as before.

    HEADACHES.

    Fever is usually accompanied by headache in front

    portion of head or behind the eyes.

    MUSCULAR ( MYALGIA) or BONE PAIN.

    Occurs after onset of fever.

    Affects legs, joints, and lumbar spine.

    Usually the pain gets severe after its onset.

    The pain may last for several weeks even after

    the fever has subsided.

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    Pain is usually absent in Dengue Hemorrhagic

    Fever/ Dengue Shock Syndrome.

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    COMPLICATIONS OF

    DENGUE FEVER..Complications, though rare may occur in dengue

    hemorrhagic fever/ dengue shock syndrome are as follows

    :

    Damage to brain due to bleeding orprolonged shock.

    Liver failure. Inflammation of the heart muscles

    [MYOCARDITIS].

    Encephalopathy (disorder of brain).

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    DIAGNOSIS..DIAGNOSIS OF DENGUE FEVER : confirmed diagnosis

    of dengue infection can be done by:

    ISOLATION OF THE VIRUS : Isolation of

    virus requires collection of serum sample

    from patients within five days after

    appearance symptoms.

    DETECTING SPECIFIC ANTIBODIES :

    Serologic requires collection of serum withinsix days after onset of symptoms. The serum

    is tested for detecting specific ant-dengue

    antibodies by Enzyme Linked Immuno

    Sorbent Assay (ELISA) .

    Antibody Titers of Igm and IgG antibody increases four-fold in serum sample.

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    TREATMENT OF

    DENGUE..

    Although no specific anti viral tablets or injections that

    can kill dengue virus are currently available, adequate

    supportive care and treatment could control its morbidity.

    There are no specific anti-viral tablets or injections that

    can kill the virus. However, a lot of supportive care and

    treatment can go a long way to save a patient suffering

    from dengue fever.

    Fever is treated by anti-pyretic like Paracetamol.

    Pain in the bone should be treated by analgesics

    or pain killing tablets.

    Patients are prone to dehydration hence they

    should drink plenty of fluids. If necessary a few

    days of intra-venous fluids can be administered

    in the form of normal saline or dextrose saline.

    In some cases, oxygen is helpful. Steroids are not

    known to help.

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    PRONOSIS OF DENGUE

    FEVER..

    Survival is usually related to early hospitalization and

    aggressive supportive treatment. Aggressive fluids and

    electrolytes can help the most affected of patients

    including children with Dengue Hemorrhagic Fever/

    Dengue Shock Syndrome who can wake up and feel

    normal. Morens, a physician states that the rapid clinical

    response to intravenous fluids is among the most

    dramatic events in clinical medicine.

    The recovery period may be slow with associated

    weakness and mental depression.

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    PREVENTION OF MOSQUITOBITES..

    Use mosquito nets during nights. Use mosquito repellant creams or coils containing

    chemical DEET to avoid mosquito bites.

    Wear bright and colored clothing, as mosquitoes areattracted towards dark clothing.

    Wear long sleeved clothes and long pants. Wear boots and socks and also if necessary tuck the

    pants into the socks.

    Avoid outdoor activities during dawn or dusk whenthese mosquitoes are most active.

    Avoid strong perfumes as mosquitoes are attractedtowards their smell.

    Store water undercover. Use bleaching powder mixed in water if it is not tube

    used for drinking.

    Measures should be taken to prevent mosquitobreeding in stored water bodies like wells.

    Destroy discarded objects like old tyres, coconutshells and bottles as they collect and store rain water.

    Avoid stagnant water around houses to get rid ofmosquito breeding sites.

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    PREVENTION OF

    MOSQUITOBREEDING..

    The onset of monsoons usually to a surge of breedingamong mosquitoes, which coexists with humans andshare the same milieu.

    Aedes aegypti mosquitoes, which are causativevectors of Dengue fever and Chikungunya carry thevirus and cause these diseases. The following shouldbe noted about Aedes mosquito :

    A. It is the female mosquito that feeds onblood as it requires the blood protein toproduce its eggs.

    B. The female Aedes mosquito searches forsuitable to lay their eggs and it is usually thestagnant water. In Delhi, 90% of thesemosquitoes were found rampantly breedingin water stagnant in coolers.

    C. The malemosquitoesusually feedonly on plantnectar.

    D. Aedesmosquitoescausing

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    dengue and chikungunya usually bite duringthe day unlike those causing malaria.

    E.Avoid stagnat water around or near houses

    to get rid of mosquito breedings.

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    REFERENCES. .

    http://www.who.int/mediacentre/

    factsheets/fs192/en/

    http://www.pubmedcentral.nih.gov/

    articlerender.fcgi?artid=179846

    http://www.emedicine.com/

    EMERG/topic124.htm

    http://www.cdc.gov/ncidod/

    dvbid/dengue/

    http://www.who.int/mediacentre/http://www.pubmedcentral.nih.gov/http://www.emedicine.com/http://www.cdc.gov/ncidod/http://www.who.int/mediacentre/http://www.pubmedcentral.nih.gov/http://www.emedicine.com/http://www.cdc.gov/ncidod/
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    DECLARATION. .

    I, Vaibhav Gupta hereby declare that I have

    completed my project work with all the best of my

    knowledge and efforts. It is now completed in all

    respects. It took a reasonable time, energy and a

    lot of efforts to successfully complete the project

    entitled, DENGUE FEVER. I am glad to announce

    that the project has completed in all respects well

    before the scheduled time.

    VAIBHAV GUPTA.

    CLASS: XII-B.

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    CERTIFICATE. .

    This is to certify that VAIBHAV GUPTA has completed

    his project. Titled as DENGUE FEVER with sincerity and

    diligence. He has completed his project work well before

    the completion of tenure. I assure that he has not used

    any unfair means and he has done the project work

    independently.

    His project may be considered as fulfillment for

    AISSCE, 2010-2011 conducted by CBSE.

    I hereby declare that she is a well behaved and

    obedient student to the best of my knowledge.

    Mr. A.K. Singh. Mrs. Urmila

    Tripathi.

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    (PRINCIPAL.) (Head of Dept. of Biology,

    PGT.)

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