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    The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons:

    Medical Operation of the 2nd

    Machine,Production and Commissioning Status of Machines No. 3 to 7

    H. Rcken, M. Abdel-Bary, E. Akcltekin, P. Budz, T. Stephani, J. Wittschen

    VARIAN Medical SystemsParticle Therapy GmbHFriedrich-Ebert-Str. 1D-51429 BERGISCH GLADBACHGERMANY

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    The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons:

    Medical Operation of the 2nd

    Machine,Production and Commissioning Status of Machines No. 3 to 7

    H. Rcken, M. Abdel-Bary, E. Akcltekin, P. Budz, T. Stephani, J. Wittschen

    VARIAN Medical SystemsParticle Therapy GmbHFriedrich-Ebert-Str. 1D-51429 BERGISCH GLADBACHGERMANY

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    4/544The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    and became in 2009

    Varian Medical Systems Particle Therapy GmbH

    Further split-ups: > RI Research Instruments GmbH> BASC Bruker Advanced Supercon GmbH

    VARIAN PT ?

    Former ACCEL Instruments

    was acquired in 2007 by

    VARIAN Medical Systems

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    5/545The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    OUTLINE

    Introduction

    Operating Cyclotrons #1 and #2Patient Treatment / Uptime Statistics

    Cyclotrons under Commissioning#3 Assembly, SC Magnet Ramping, Test Quench, Magnetic Field Mapping

    Examples for New ComponentsSolid State Amplifier, Digital Low Level RF

    Cyclotron Production Site

    Production of Next Machines#4, #5, #6, #7

    Cyclotron and Scanning Nozzle Test Cell

    Conclusion

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    6/546The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Beam - Energy 250 MeV- Extracted current (max) 800 nA- Emittance of extracted beam < 3 / 5 mm mrad (2 )- Momentum spread p/p 0.04% (i.e. 200keV @ 250MeV)- Number of turns 650- Extraction efficiency (multi-turn extraction mode) ~80%- Dynamic range for intensity modulation 1:800- Fast intensity modulation via electrostatic deflector, >10% in 100 s

    VARIAN PT Cyclotron System Parameters(Engineering Goals)

    RF System - Frequency 72.8 MHz (2 nd harmonic)- Voltage source to puller / @ extraction radius 80 kV / 130 kV

    - RF power 115 kW

    Iron Yoke - Outer diameter 3.1 m- Height 1.6 m- Weight

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    Lanzhou, China

    Operating VARIAN PT Cyclotrons #1 and #2

    1. Paul Scherrer Institut PSI (CH), treating patients since beginning of 2007.

    2. Rinecker Proton Therapy Center RPTC (D) treating patients since

    beginning of 2009!This facility is widely equipped with VARIAN technology, like

    superconducting compact 250 MeV proton cyclotrondegrader for energy adjustmentenergy selection system for energy filteringbeam line for beam transportation

    4 rotational isocentric gantries for 360

    irradiation+ 1 fixed beam for head / neck treatmentsdelivery nozzles providing pencil beam spot scanningsafety systems

    treatment control software

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    Lanzhou, China

    Patient Treatment at RPTC

    On website

    www.rptc.de :

    PATIENT TREATMENTSTARTED MARCH 16 th, 2009

    TREATMENT REPORTS ARE AVAILABLE

    STATUS REPORTS AND

    MEDICAL CASE STUDIES ARE AVAILABLE

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    Lanzhou, China

    Patient Treatment at RPTC

    On website

    www.rptc.de :

    PATIENT TREATMENTSTARTED MARCH 16 th, 2009

    TREATMENT REPORTS ARE AVAILABLE

    STATUS REPORTS AND

    MEDICAL CASE STUDIES ARE AVAILABLE

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    10/5410The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    RPTC Uptime during Patient Treatment

    RPTC presentation on

    PTCOG 48 conference(specialized particletherapy event)

    6 months after start of operation:

    Poster presented by RPTC at PTCOG 48

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    The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under CommissioningCyclotron #3 Assembly and FAT

    Cyclotron #3 will be widely pre-assembled,

    tested (with beam!) in the factory,

    and shipped to its destination in

    2 large lots (upper / lower part).

    It is currently in the final stageof assembly and is undergoingFATs in parallel.

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    The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under CommissioningCyclotron #3 Assembly and FAT

    Cyclotron #3 will be widely pre-assembled,

    tested (with beam!) in the factory,

    and shipped to its destination in

    2 large lots (upper / lower part).

    It is currently in the final stageof assembly and is undergoingFATs in parallel.

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    14The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under Commissioning#3 SC Magnet Ramping and Test Quench

    First excitation of thesuperconducting magnet tookplace on May 18, 2010 on thefirst attempt.

    The obligatory test quenchcould not be forced by fast

    ramping and had to betriggered by the dedicatedquench heaters.

    After cool down (5 hrs) allforces on the support links aswell as the magnetic fieldmap remained unchanged:

    stable, quench proof andquench tolerant system

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    15The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under Commissioning#3 SC Magnet Ramping and Test Quench

    First excitation of thesuperconducting magnet tookplace on May 18, 2010 on thefirst attempt.

    The obligatory test quenchcould not be forced by fast

    ramping and had to betriggered by the dedicatedquench heaters.

    After cool down (5 hrs) allforces on the support links aswell as the magnetic fieldmap remained unchanged:

    stable, quench proof andquench tolerant system

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    16The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under Commissioning#3 SC Magnet Ramping and Test Quench

    First excitation of thesuperconducting magnet tookplace on May 18, 2010 on thefirst attempt.

    The obligatory test quenchcould not be forced by fast

    ramping and had to betriggered by the dedicatedquench heaters.

    After cool down (5 hrs) allforces on the support links aswell as the magnetic fieldmap remained unchanged:

    stable, quench proof andquench tolerant system

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    17The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    A measured field map

    VARIAN PT Cyclotrons under Commissioning#3 Magnetic Field Mapping

    Initially the field showed afirst harmonic of ~29 Gauss.

    is compared to itssymmetrized form to revealdeviations from perfect 4-foldsymmetry.

    This could be compensated

    Some remaining deviationson the extraction radius mustbe shimmed locally.

    down to

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    18The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    A measured field map

    VARIAN PT Cyclotrons under Commissioning#3 Magnetic Field Mapping

    1 st Harmonic of Initial Field Map

    29 Gauss

    Initially the field showed afirst harmonic of ~29 Gauss.

    is compared to itssymmetrized form to revealdeviations from perfect 4-foldsymmetry.

    This could be compensated

    Some remaining deviationson the extraction radius mustbe shimmed locally.

    down to

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    19The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    A measured field map

    VARIAN PT Cyclotrons under Commissioning#3 Magnetic Field Mapping

    1 st Harmonic of Initial Field Map

    29 Gauss

    Initially the field showed afirst harmonic of ~29 Gauss.

    is compared to itssymmetrized form to revealdeviations from perfect 4-foldsymmetry.

    This could be compensated

    Some remaining deviationson the extraction radius mustbe shimmed locally.

    down to

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    20The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    RF power amplifiers used at PSI and RPTC:3-stage tetrode tube based , several electrical cabinetsfor power transformers and high voltage supplies

    Supplied byCryoelectra GmbH

    New design is tested:transistor based , 20 parallel working RF power modulesTest setup completed a >1000h test with 25kW,

    allowed reflected power limit >15%

    VARIAN PT Cyclotrons under CommissioningSolid State Amplifier

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    21The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Currently the final setup consisting of 6 cabinets with a total of 120 power

    modules is under test in the factory.

    VARIAN PT Cyclotrons under CommissioningSolid State Amplifier

    Via its redundancy, the design features ahigher

    - availability,- maintainability,- cost reduction, ...

    The digitally controlled modularizedsystem provides extended diagnosticscapabilities.

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    24The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under CommissioningDigital Low Level RF

    VARIAN will use a digital LLRF with itsfuture systems.

    Supplied byCryoelectra GmbH

    The dLLRF has already passedperformance tests at the supplier andwill be delivered in September to theVARIAN factory for system integrationtests.

    Like the SSAmp, the dLLRF is designedfor high redundancy. This yields a high

    fault tolerance and increases systemuptime.

    The dLLRF is faster than the previouslyused system and provides much morediagnostic signals and functionality.

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    25The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under CommissioningDigital Low Level RF

    VARIAN will use a digital LLRF with itsfuture systems.

    Supplied byCryoelectra GmbH

    The dLLRF has already passedperformance tests at the supplier andwill be delivered in September to theVARIAN factory for system integrationtests.

    Like the SSAmp, the dLLRF is designedfor high redundancy. This yields a high

    fault tolerance and increases systemuptime.

    The dLLRF is faster than the previouslyused system and provides much morediagnostic signals and functionality.

    l d

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    26The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotrons under CommissioningDigital Low Level RF

    VARIAN will use a digital LLRF with itsfuture systems.

    Supplied byCryoelectra GmbH

    The dLLRF has already passedperformance tests at the supplier andwill be delivered in September to theVARIAN factory for system integrationtests.

    Like the SSAmp, the dLLRF is designedfor high redundancy. This yields a high

    fault tolerance and increases systemuptime.

    The dLLRF is faster than the previouslyused system and provides much morediagnostic signals and functionality.

    VARIAN PT C l P d i Si

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    27The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production SiteOverview

    Production site nearCologne / Germany

    Allows assembly ofup to 6 cyclotrons in

    parallel

    and up to 8 - 12

    cyclotrons / year

    VARIAN PT C l P d i Si

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    28The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production SiteOverview

    Production site nearCologne / Germany

    Allows assembly ofup to 6 cyclotrons in

    parallel

    and up to 8 - 12

    cyclotrons / year

    VARIAN PT C l t P d ti Sit

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    29The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production Site Assembly Stands

    VARIAN PT C l t P d ti Sit

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    30The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production Site Assembly Stands

    VARIAN PT Cyclotron Production Site

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    31The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production Site Assembly Stands

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    VARIAN PT Cyclotron Production Site

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    33The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production Site Assembly Stands

    VARIAN PT Cyclotron Production Site

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    34The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production Site Assembly Stands

    VARIAN PT Cyclotron Production Site

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    35The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    VARIAN PT Cyclotron Production Site Assembly Stands

    Production of Next Machines

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    36The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Production of Next Machines#4, #5, #6, #7

    #4: All major componentsare ready, coil winding andassembly of pole caps is

    underway#5: Fine machined ironyoke and pole caps are inthe factory underinspection

    #6, #7: Iron parts and longlead items are ordered(iron is casted and forged these days)

    Expected build sequenceis ~2 cyclotrons per year at

    the moment

    #4 coil windingpole caps

    yoke rings #5 pole capsyoke rings

    Cyclotron and Scanning Nozzle Test Cell

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    37The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Cyclotron and Scanning Nozzle Test CellFactory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    38The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Cyclotron and Scanning Nozzle Test CellFactory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    39The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Cyclotron and Scanning Nozzle Test CellFactory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    40The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    y gFactory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    41The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    y gFactory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    42The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    y gFactory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    43The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    y gFactory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

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    Cyclotron and Scanning Nozzle Test Cell

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    45The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Factory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    46The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Factory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    47The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Factory Beam Test Plans

    Adjacent to the manufacturing hallVARIAN has built a concrete bunkerfor cyclotron and scanning nozzle

    tests, the so-called Test Cell.This enables the delivery of factorybeam tested systems.

    The Test Cell is finalized this monthand cyclotron #3 will move in aftermagnetic shimming.

    Cyclotron and Scanning Nozzle Test Cell

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    48The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Factory Beam Test Plans

    We plan to test all RF components,ion source, slit systems, extractors, diagnostics, etc.

    during a system integration and FAT for cyclotron #3 in this year.

    Cyclotron and Scanning Nozzle Test CellF B T Pl

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    49The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Factory Beam Test Plans

    We plan to test all RF components,ion source, slit systems, extractors, diagnostics, etc.

    during a system integration and FAT for cyclotron #3 in this year.

    VARIAN PT Superconducting Proton CyclotronsF D l

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    50The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Future Developments

    The proven design

    which was built in the past

    will be improved continuouslyfor the VARIAN PT Cyclotronwith regard to reliability maintainability performance upgrades cost reduction

    Ion Source, Solid State Amplifier,Dee Noses, Digital LLRF, Simplified Media Supply,Iron, Cryosystem, Extraction System, and so on

    VARIAN PT Superconducting Proton CyclotronsF t D l t

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    51The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Future Developments

    The proven design

    which was built in the past

    will be improved continuouslyfor the VARIAN PT Cyclotronwith regard to reliability maintainability performance upgrades cost reduction

    Ion Source, Solid State Amplifier,Dee Noses, Digital LLRF, Simplified Media Supply,Iron, Cryosystem, Extraction System, and so on

    VARIAN PT Superconducting Proton CyclotronsFuture Developments

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    52The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    Future Developments

    The proven design

    which was built in the past

    will be improved continuouslyfor the VARIAN PT Cyclotronwith regard to reliability maintainability performance upgrades cost reduction

    Ion Source, Solid State Amplifier,Dee Noses, Digital LLRF, Simplified Media Supply,Iron, Cryosystem, Extraction System, and so on

    ConclusionOperating & Future VARIAN PT Cyclotrons

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    53The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    * Iron #5 is under inspection in the factory.

    * Cyclotron #3 is currently undergoing FATs.

    * Cyclotron #4 parts are currently assembled in the VARIAN factory.

    * Irons #6 and #7 are currently being casted and forged

    Operating & Future VARIAN PT Cyclotrons

    * Paul Scherrer Institute (PSI), treating patients since beginning of 2007.

    * Rinecker Proton Therapy Center (RPTC), treating patients sincebeginning of 2009. Gantry #4 @RPTC is handed over right now.

    * A contract for the next complete PT installation with a customer from theUSA has been signed.

    * There are more projects in Europe and the USA in the pipeline.

    more to come

    Teams Charity Run

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    54The VARIAN 250 MeV Superconducting Compact Proton Cyclotrons

    Lanzhou, China

    for the Childrens Cancer Ward of the University Hospital in Cologne:

    Thank you!