Table S2 Brain specific gene list enrichment analysis of each cluster from WGCNAanalysis of the Brain Span Data using userListEnrichmentR

Cluster Brain-Specific Categories P values*B0 Neuron_probable__Cahoy 5.70E-25B0 Astrocyte_probable__Cahoy 1.88E-17B0 DownWithAlzheimers_Blalock__ADvsCT_inCA1 1.08E-14B0 Oligodendrocyte_probable__Cahoy 1.75E-13B0 turquoise_M9_Oligodendrocyte__CTX 2.95E-13B0 brown_M3_Astrocytes__HumanMeta 4.96E-12B0 brown_M15_Astrocyte__CTX 3.38E-11B0 turquoise_Cerebellum__HumanChimp 7.27E-11B0 turquoise_M14_Nucleus__HumanMeta 3.64E-10B0 turquoise_upAging_oligo__Lu_Aging 4.14E-10B0 Neuron_definite__Cahoy 1.16E-09B0 blue_M2_Oligodendrocytes__HumanMeta 1.34E-09B0 yellow_M18__CTX 9.22E-09B0 UpWithAlzheimers_Blalock__ADvsCT_inCA1 2.82E-08B0 yellow_Caudate__HumanChimp 2.87E-08B0 blue_M16_Neuron__CTX 3.18E-08B0 DownWithAlzheimers_Liang__ADvsCT_inCA1 8.77E-08B0 Autism_differential_expression_across_at_least_one_comparison__Voineagu 8.92E-08B0 turquoise_M14_Nucleus__MouseMeta 1.19E-07B0 Autism_associated_module_M12__Voineagu 2.30E-07B0 brown_Cortex__HumanChimp 2.61E-07B0 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 4.04E-07B0 green_M10_GlutamatergicSynapticFunction__CTX 4.45E-07B0 green_M5_Mitochondria__HumanMeta 2.18E-06B0 blue_downAging_mitochondria_synapse__Lu_Aging 2.92E-06B0 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 7.08E-06B0 yellow_noChangeAD_antigenProcessing_ribosome__Blalock_AD 8.80E-06B0 Autism_differential_splicing_events__Voineagu 2.40E-05B0 GlutamatergicNeuronsInMouseCortex_Sugino__MO 2.98E-05B0 greenyellow_downAD_ionAndCalciumTransport__Blalock_AD 9.49E-05B0 tan_M13_Neuron__MouseMeta 0.00015008B0 pink_downAD_synapticTransmission__Blalock_AD 0.000153665B0 GABAergicNeuronsInMouseCortex_Sugino__MO 0.000185453B0 upActivationMicroglia_3treatments_Thomas__MicrogialMarkers 0.000199627B0 pink_glutamatergicNeurons__Sugino/Winden 0.000217426B0 Down_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.000223218

B0 Neuron__ABA 0.000231979B0 Schizophrenia_possible__DiseaseGenes 0.00031517B0 greenyellow_M6_GlutatmatergicSynapse__HumanMeta 0.000501738B0 Oligodendrocyte__ABA 0.000561568B0 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.000679662B0 black_M11__CTX 0.000897484B0 UpWithAlzheimers_Liang__ADvsCT_inCA1 0.000914922B0 Somatic__MitochondrialType 0.000927884B0 turquoise_CingulateNeurons(allTypes)/Layer5__Sugino/Winden 0.001195257B0 purple_downAD_synapticTransmission__Blalock_AD 0.001278084B0 CA1specific_Newrzella__CA1vsCA3 0.001374272B0 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 0.001720985B0 turquoise_downAD_intracellularTransport_cytoskeleton__Blalock_AD 0.001732939B0 palegreen_M1_Gender__CTX 0.001775912B0 green_CortexAndCerebellum__HumanChimp 0.001871469B0 brown_upAging_copperHomeostatisMT1__Lu_Aging 0.002227017B0 blue_Cortex__HumanChimp 0.002369436B0 tan_M13_Neuron__HumanMeta 0.002609245B0 red_ACCandCaudate__HumanChimp 0.003716094B0 black_noChangeAD_heatShockProteinActivity__Blalock_AD 0.004076999B0 tan_noChangeAD_oligo_plasmaMembrane__Blalock_AD 0.004640058B0 green_glutamatergicNeurons__Sugino/Winden 0.004648375B0 red_M11_Neuron__HumanMeta 0.004872087B0 red_upAD_transferase_oncogenesis__Blalock_AD 0.005529291B0 yellow_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)/LGN__Sugino/Winden 0.0058732B0 brown_downAD_mitochondrion__Blalock_AD 0.0062813B0 upMacrophageAndMGactivagtion_GSE1910__MicrogialMarkers 0.007096243B0 magenta_downAD_synapticTransmission__Blalock_AD 0.008122733B0 green_M5_Mitochondria__MouseMeta 0.008214114B0 black_M1_PvalbInterneurons__HumanMeta 0.009243998B0 magenta_M8_Microglia(Type2)__HumanMeta 0.010422523B0 Nucleus_Foster__MO 0.0211667B0 upInFrontalCortex__EarlyAD 0.027391798B1 Autism_differential_expression_across_at_least_one_comparison__Voineagu 3.56E-44B1 Astrocyte_probable__Cahoy 2.29E-42B1 Neuron_probable__Cahoy 8.59E-31B1 DownWithAlzheimers_Blalock__ADvsCT_inCA1 1.17E-30B1 brown_M15_Astrocyte__CTX 5.71E-26B1 Autism_associated_module_M12__Voineagu 2.77E-25B1 brown_M3_Astrocytes__HumanMeta 2.85E-23B1 Astrocyte_definite__Cahoy 1.66E-19B1 green_M5_Mitochondria__HumanMeta 1.23E-18B1 blue_downAging_mitochondria_synapse__Lu_Aging 2.09E-18

B1 brown_Cortex__HumanChimp 2.60E-18B1 GlutamatergicNeuronsInMouseCortex_Sugino__MO 3.61E-15B1 Neuron_definite__Cahoy 3.86E-14B1 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 5.72E-12B1 brown_downAD_mitochondrion__Blalock_AD 8.19E-12B1 Somatic__MitochondrialType 1.49E-11B1 Neuron__ABA 2.67E-11B1 magenta_M8_Microglia(Type2)__HumanMeta 1.27E-10B1 DownWithAlzheimers_Liang__ADvsCT_inCA1 3.51E-10B1 green_glutamatergicNeurons__Sugino/Winden 4.43E-10B1 red_M11_Neuron__HumanMeta 5.68E-10B1 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 1.48E-09B1 turquoise_M9_Oligodendrocyte__CTX 5.50E-09B1 Schizophrenia_possible__DiseaseGenes 6.27E-09B1 pink_downAD_synapticTransmission__Blalock_AD 7.41E-09B1 tomato_M17_Interneurons__CTX 7.96E-09B1 Synaptic__MitochondrialType 8.72E-09B1 black_M1_PvalbInterneurons__HumanMeta 9.17E-09B1 blue_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)__Sugino/Winden 2.18E-08B1 turquoise_CingulateNeurons(allTypes)/Layer5__Sugino/Winden 4.16E-08B1 purple_downAD_synapticTransmission__Blalock_AD 4.33E-08B1 brown_upAging_copperHomeostatisMT1__Lu_Aging 6.46E-08B1 blue_Cortex__HumanChimp 6.55E-08B1 red_ACCandCaudate__HumanChimp 6.93E-08B1 green_M10_GlutamatergicSynapticFunction__CTX 1.33E-07B1 Alzheimer_possible__DiseaseGenes 9.83E-07B1 blue_M16_Neuron__CTX 1.40E-06B1 Astrocyte__ABA 1.46E-06B1 magenta_downAD_synapticTransmission__Blalock_AD 2.90E-06B1 Parkinson_possible__DiseaseGenes 2.96E-06B1 greenyellow_downAD_ionAndCalciumTransport__Blalock_AD 3.02E-06B1 CA3specific_Newrzella__CA1vsCA3 3.73E-06B1 yellow_Caudate__HumanChimp 3.98E-06B1 orange_M5_Microglia(Type2)__CTX 5.74E-06B1 GABAergicNeuronsInMouseCortex_Sugino__MO 8.69E-06B1 CA1specific_Newrzella__CA1vsCA3 1.97E-05B1 PresynapticCompartmentProteins_Morciano__MO 2.17E-05B1 Mitochondria_Foster__MO 6.36E-05B1 tan_M13_Neuron__MouseMeta 6.76E-05B1 magenta_M8_Microglia(Type2)__MouseMeta 7.55E-05B1 greenyellow_M6_GlutatmatergicSynapse__HumanMeta 0.000128248B1 turquoise_upAging_oligo__Lu_Aging 0.000163826B1 yellow_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)/LGN__Sugino/Winden 0.000240909

B1 DownWithAlzheimers_Colangelo__ADvsCT_inCA1 0.000287912B1 blue_M2_Oligodendrocytes__HumanMeta 0.000292772B1 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.000299824B1 Parkinsons_probable__DiseaseGenes 0.000419152B1 lightyellow_telencephalicInterneurons__Sugino/Winden 0.000507477B1 darkolivegreen_M6_PvalbInterneurons__CTX 0.000677922B1 Validated_Astrocyte_Bachoo__MO 0.00069889B1 CA3specific_Torres__CA1vsCA3 0.001129701B1 midnightblue_pyramidalNeurons_Layers5&6/basolateralAmygdala__Sugino/Winden 0.0012165B1 Autism_differential_splicing_events__Voineagu 0.001585789B1 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.001602811B1 pink_M10_Microglia(Type1)__MouseMeta 0.00234809B1 downInFrontalCortex__EarlyAD 0.002528264B1 CA1specific_GorLorT__CA1vsCA3 0.002571853B1 MultipleSclerosis_probable__DiseaseGenes 0.004710643B1 green_CortexAndCerebellum__HumanChimp 0.005023705B1 upInHippocampus__EarlyAD 0.00530172B1 Cytoplasm_Foster__MO 0.006116404B1 red_LGN_interneurons__Sugino/Winden 0.006167548B1 tan_M12_Hypoxia__CTX 0.006640863B1 Autism_susceptability_genes_from_Pinto_et_al_2010__Voineagu 0.00731337B1 honeydew_M7_Mitochondria__CTX 0.009031335B1 mutationMouseOrHumanOrBoth__JAXdiseaseGene 0.010127826B1 cyan_M4_Mitochondria__HumanMeta 0.012677843B1 SZGene_2+_26Mar08__MO 0.013466946B1 turquoise_M14_Nucleus__MouseMeta 0.014465623B1 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.015526959B1 pink_M10_Microglia(Type1)__HumanMeta 0.015988432B1 CA3specific_GorLorT__CA1vsCA3 0.017699292B1 upInFrontalCortex__EarlyAD 0.018134955B1 cyan_M4_Mitochondria__MouseMeta 0.020306693B1 downActivationMicroglia_3treatments_Thomas__MicrogialMarkers 0.024725905B1 UpWithAlzheimers_Liang__ADvsCT_inCA1 0.024832046B1 mutationHuman__JAXdiseaseGene 0.025766444B1 CA1specific_Lein__CA1vsCA3 0.027232555B1 downInHippocampus__EarlyAD 0.02918158B1 upMGactivagtion_GSE1910__MicrogialMarkers 0.033132161B1 salmon_M12_Ribosome__HumanMeta 0.034371431B1 yellow_noChangeAD_antigenProcessing_ribosome__Blalock_AD 0.038290644B1 red_M19__CTX 0.044064443B1 pink_M14_GlutamatergicSynapticFunction__CTX 0.045313499B2 turquoise_Cerebellum__HumanChimp 5.85E-07B2 Autism_differential_expression_across_at_least_one_comparison__Voineagu 1.63E-06

B2 Astrocyte_probable__Cahoy 2.10E-06B2 red_ACCandCaudate__HumanChimp 9.35E-06B2 Schizophrenia_possible__DiseaseGenes 2.49E-05B2 Astrocyte_definite__Cahoy 4.06E-05B2 mutationMouseOrHumanOrBoth__JAXdiseaseGene 4.24E-05B2 brown_M3_Astrocytes__HumanMeta 7.88E-05B2 yellow_M18__CTX 0.000122808B2 brown_upAging_copperHomeostatisMT1__Lu_Aging 0.000172223B2 Autism_associated_module_M12__Voineagu 0.00017593B2 blue_M16_Neuron__CTX 0.000211893B2 green_M5_Mitochondria__HumanMeta 0.000247393B2 turquoise_M14_Nucleus__MouseMeta 0.000743355B2 Oligodendrocyte_definite__Cahoy 0.000951945B2 mutationMouseAndHuman__JAXdiseaseGene 0.000978887B2 Somatic__MitochondrialType 0.001016227B2 pink_M10_Microglia(Type1)__HumanMeta 0.001420763B2 mutationHuman__JAXdiseaseGene 0.001603858B2 turquoise_M14_Nucleus__HumanMeta 0.001799557B2 turquoise_M9_Oligodendrocyte__CTX 0.002047935B2 upMGactivagtion_GSE1910__MicrogialMarkers 0.002254657B2 upInFrontalCortex__EarlyAD 0.002557369B2 blue_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)__Sugino/Winden 0.002725588B2 GlutamatergicNeuronsInMouseCortex_Sugino__MO 0.003263102B2 Mitochondria_Foster__MO 0.003344381B2 Neuron__ABA 0.004200504B2 blue_M2_Oligodendrocytes__HumanMeta 0.00590741B2 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.006526134B2 brown_Cortex__HumanChimp 0.006940411B2 purple_pyramidalNeurons_Layers5&6/basolateralAmygdala__Sugino/Winden 0.0096638B2 cyan_M4_Mitochondria__HumanMeta 0.013410468B2 salmon_M12_Ribosome__HumanMeta 0.013513257B2 tan_noChangeAD_oligo_plasmaMembrane__Blalock_AD 0.014341551B2 magenta_M8_Microglia(Type2)__HumanMeta 0.01764588B2 black_M1_PvalbInterneurons__HumanMeta 0.021472624B2 Astrocyte__ABA 0.022443849B2 Validated_Astrocyte_Bachoo__MO 0.024065931B2 upActivationMicroglia_3treatments_Thomas__MicrogialMarkers 0.025552776B2 brown_pyramidalNeurons_Layer5/basolateralAmygdala__Sugino/Winden 0.02699477B2 brown_M15_Astrocyte__CTX 0.029628349B2 Neuron_definite__Cahoy 0.030574875B2 black_WhiteMatter__HumanChimp 0.033347181B2 Cytoplasm_Foster__MO 0.03443119B2 Alzheimer_possible__DiseaseGenes 0.034962409

B2 greenyellow_GABAergicNeurons__Sugino/Winden 0.037993521B2 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 0.040658865B2 black_M11__CTX 0.041504457B2 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.041863356B3 Neuron_probable__Cahoy 2.91E-09B3 Nucleus_Foster__MO 8.19E-08B3 turquoise_M14_Nucleus__HumanMeta 1.14E-05B3 turquoise_M14_Nucleus__MouseMeta 3.70E-05B3 salmon_M12_Ribosome__HumanMeta 0.000114004B3 Autism_associated_module_M12__Voineagu 0.000201805B3 pink_glutamatergicNeurons__Sugino/Winden 0.000264712B3 Down_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.000313328B3 Schizophrenia_possible__DiseaseGenes 0.000972033B3 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.001660003B3 Neuron_definite__Cahoy 0.001679015B3 Oligodendrocyte_probable__Cahoy 0.002241569B3 pink_downAD_synapticTransmission__Blalock_AD 0.002926168B3 blue_downAging_mitochondria_synapse__Lu_Aging 0.005419802B3 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.005579133B3 turquoise_Cerebellum__HumanChimp 0.006741357B3 Parkinson_possible__DiseaseGenes 0.016546904B3 brown_Cortex__HumanChimp 0.017822462B3 Astrocyte_definite__Cahoy 0.019739304B3 honeydew_M7_Mitochondria__CTX 0.033634707B3 brown_downAD_mitochondrion__Blalock_AD 0.042422824B3 greenyellow_downAD_ionAndCalciumTransport__Blalock_AD 0.043954288B3 SZGene_2+_26Mar08__MO 0.044381362B3 Autism_susceptability_genes_from_Pinto_et_al_2010__Voineagu 0.048724176B4 Astrocyte_probable__Cahoy 9.98E-12B4 Neuron_probable__Cahoy 1.68E-10B4 DownWithAlzheimers_Blalock__ADvsCT_inCA1 2.83E-06B4 Autism_associated_module_M12__Voineagu 2.90E-05B4 Neuron_definite__Cahoy 4.05E-05B4 DownWithAlzheimers_Liang__ADvsCT_inCA1 0.000928067B4 Down_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.00112386B4 Parkinson_possible__DiseaseGenes 0.001700547B4 Nucleus_Foster__MO 0.001780608B4 mutationMouse__JAXdiseaseGene 0.002693154B4 brown_M3_Astrocytes__HumanMeta 0.003260358B4 red_M11_Neuron__HumanMeta 0.003444208B4 blue_downAging_mitochondria_synapse__Lu_Aging 0.003527404B4 green_M5_Mitochondria__HumanMeta 0.003839749B4 turquoise_CingulateNeurons(allTypes)/Layer5__Sugino/Winden 0.00753781

B4 Oligodendrocyte_probable__Cahoy 0.009207777B4 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 0.00948464B4 green_M10_GlutamatergicSynapticFunction__CTX 0.010706386B4 blue_M16_Neuron__CTX 0.012692835B4 Astrocyte_definite__Cahoy 0.015111712B4 mutationMouseOrHumanOrBoth__JAXdiseaseGene 0.018100305B4 turquoise_Cerebellum__HumanChimp 0.019360346B4 turquoise_upAging_oligo__Lu_Aging 0.021562641B4 brown_downAD_mitochondrion__Blalock_AD 0.028250971B4 black_M1_PvalbInterneurons__HumanMeta 0.032424471B4 greenyellow_M6_GlutatmatergicSynapse__HumanMeta 0.034023342B4 purple_downAD_synapticTransmission__Blalock_AD 0.034428935B4 mutationHuman__JAXdiseaseGene 0.035433252B4 pink_downAD_synapticTransmission__Blalock_AD 0.036773298B4 brown_Cortex__HumanChimp 0.03700242B4 Autism_susceptability_genes_from_Pinto_et_al_2010__Voineagu 0.046247539B5 Astrocyte_probable__Cahoy 4.02E-08B5 turquoise_Cerebellum__HumanChimp 2.61E-05B5 blue_M16_Neuron__CTX 7.71E-05B5 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.000186842B5 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.000553297B5 green_M5_Mitochondria__HumanMeta 0.000992393B5 Neuron_probable__Cahoy 0.001235521B5 brown_M15_Astrocyte__CTX 0.001851753B5 DownWithAlzheimers_Blalock__ADvsCT_inCA1 0.002231498B5 brown_Cortex__HumanChimp 0.009644903B5 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.011102574B5 turquoise_M9_Oligodendrocyte__CTX 0.012495347B5 yellow_M18__CTX 0.014796855B5 CA1specific_Newrzella__CA1vsCA3 0.015415116B5 GlutamatergicNeuronsInMouseCortex_Sugino__MO 0.019614278B5 brown_downAD_mitochondrion__Blalock_AD 0.020253387B5 Oligodendrocyte_probable__Cahoy 0.030336617B5 turquoise_M14_Nucleus__HumanMeta 0.037477682B5 red_M11_Neuron__HumanMeta 0.038705168B5 brown_M3_Astrocytes__HumanMeta 0.041329358B6 DownWithAlzheimers_Blalock__ADvsCT_inCA1 1.47E-15B6 Neuron_probable__Cahoy 1.22E-12B6 Astrocyte_probable__Cahoy 2.17E-12B6 DownWithAlzheimers_Liang__ADvsCT_inCA1 1.58E-09B6 turquoise_M9_Oligodendrocyte__CTX 3.45E-09B6 brown_M15_Astrocyte__CTX 6.06E-09B6 Oligodendrocyte_probable__Cahoy 4.93E-08

B6 turquoise_M14_Nucleus__MouseMeta 1.29E-06B6 brown_M3_Astrocytes__HumanMeta 1.71E-06B6 turquoise_upAging_oligo__Lu_Aging 1.74E-06B6 yellow_M18__CTX 2.70E-06B6 turquoise_Cerebellum__HumanChimp 2.25E-05B6 blue_M16_Neuron__CTX 0.000100848B6 blue_M2_Oligodendrocytes__HumanMeta 0.000196645B6 green_M10_GlutamatergicSynapticFunction__CTX 0.000205065B6 brown_downAD_mitochondrion__Blalock_AD 0.000206539B6 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.00027239B6 GlutamatergicNeuronsInMouseCortex_Sugino__MO 0.000295081B6 red_M11_Neuron__HumanMeta 0.000296366B6 Neuron_definite__Cahoy 0.000301265B6 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.000346027B6 blue_downAging_mitochondria_synapse__Lu_Aging 0.000761988B6 turquoise_M14_Nucleus__HumanMeta 0.000804829B6 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.000887398B6 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 0.000977934B6 Autism_associated_module_M12__Voineagu 0.001717488B6 blue_Cortex__HumanChimp 0.002645159B6 brown_Cortex__HumanChimp 0.00383513B6 turquoise_CingulateNeurons(allTypes)/Layer5__Sugino/Winden 0.005070509B6 CA3specific_Newrzella__CA1vsCA3 0.006329734B6 UpWithAlzheimers_Liang__ADvsCT_inCA1 0.007041912B6 black_M11__CTX 0.010466121B6 Down_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.014922299B6 red_upAD_transferase_oncogenesis__Blalock_AD 0.015767136B6 green_M5_Mitochondria__HumanMeta 0.01677253B6 yellow_noChangeAD_antigenProcessing_ribosome__Blalock_AD 0.018919392B6 pink_M10_Microglia(Type1)__HumanMeta 0.023298393B6 Synaptic__MitochondrialType 0.023398501B6 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.028130516B6 yellow_M15_unknown__HumanMeta 0.0331611B6 pink_glutamatergicNeurons__Sugino/Winden 0.034632524B6 tan_M13_Neuron__MouseMeta 0.034961291B7 Neuron_probable__Cahoy 2.77E-17B7 Astrocyte_probable__Cahoy 6.79E-16B7 DownWithAlzheimers_Blalock__ADvsCT_inCA1 9.61E-16B7 Oligodendrocyte_probable__Cahoy 3.61E-13B7 Autism_differential_expression_across_at_least_one_comparison__Voineagu 2.45E-10B7 blue_M16_Neuron__CTX 4.96E-08B7 turquoise_Cerebellum__HumanChimp 5.82E-08B7 turquoise_M14_Nucleus__HumanMeta 5.82E-08

B7 yellow_M18__CTX 1.93E-07B7 turquoise_M14_Nucleus__MouseMeta 3.06E-07B7 brown_M15_Astrocyte__CTX 1.97E-06B7 turquoise_M9_Oligodendrocyte__CTX 3.04E-06B7 green_M10_GlutamatergicSynapticFunction__CTX 3.83E-06B7 DownWithAlzheimers_Liang__ADvsCT_inCA1 6.80E-06B7 blue_M2_Oligodendrocytes__HumanMeta 2.36E-05B7 CA1specific_Newrzella__CA1vsCA3 0.000208404B7 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.000231713B7 blue_downAging_mitochondria_synapse__Lu_Aging 0.000295319B7 yellow_M15_unknown__MouseMeta 0.000329015B7 brown_M3_Astrocytes__HumanMeta 0.000426385B7 Neuron_definite__Cahoy 0.000444327B7 turquoise_upAging_oligo__Lu_Aging 0.000732548B7 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.000732548B7 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.00124744B7 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 0.001459101B7 green_M5_Mitochondria__HumanMeta 0.002158643B7 Autism_associated_module_M12__Voineagu 0.003532816B7 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.004905985B7 turquoise_downAD_intracellularTransport_cytoskeleton__Blalock_AD 0.005835314B7 GABAergicNeuronsInMouseCortex_Sugino__MO 0.006903222B7 green_glutamatergicNeurons__Sugino/Winden 0.007226609B7 black_M1_PvalbInterneurons__HumanMeta 0.015651646B7 red_LGN_interneurons__Sugino/Winden 0.016101964B7 brown_downAD_mitochondrion__Blalock_AD 0.020004841B7 Autism_susceptability_genes_from_Pinto_et_al_2010__Voineagu 0.023391497B7 brown_pyramidalNeurons_Layer5/basolateralAmygdala__Sugino/Winden 0.024283578B7 CA3specific_Newrzella__CA1vsCA3 0.025960551B7 brown_Cortex__HumanChimp 0.027009687B7 red_M11_Neuron__HumanMeta 0.027168037B7 GlutamatergicNeuronsInMouseCortex_Sugino__MO 0.027326104B7 Autism_differential_splicing_events__Voineagu 0.032711174B7 pink_M10_Microglia(Type1)__HumanMeta 0.036032258B7 Plasma_membrane_Foster__MO 0.036032258B7 Synaptic__MitochondrialType 0.036411745B7 yellow_noChangeAD_antigenProcessing_ribosome__Blalock_AD 0.038764911B7 Cytoplasm_Foster__MO 0.038984141B7 cyan_M4_Mitochondria__MouseMeta 0.048051231B7 turquoise_CingulateNeurons(allTypes)/Layer5__Sugino/Winden 0.048820771B8 Neuron_probable__Cahoy 1.41E-16B8 Neuron_definite__Cahoy 5.64E-06B8 blue_Cortex__HumanChimp 2.77E-05

B8 tan_M13_Neuron__HumanMeta 0.006581621B8 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 0.010230309B8 Autism_differential_splicing_events__Voineagu 0.015397825B8 greenyellow_downAD_ionAndCalciumTransport__Blalock_AD 0.018858864B8 blue_downAging_mitochondria_synapse__Lu_Aging 0.029969353B8 turquoise_M14_Nucleus__HumanMeta 0.033860496B8 Early_endosome_Foster__MO 0.034996382B8 Schizophrenia_probable__DiseaseGenes 0.034996382B8 pink_downAD_synapticTransmission__Blalock_AD 0.037325517B8 DownWithAlzheimers_Blalock__ADvsCT_inCA1 0.040708507B9 blue_M2_Oligodendrocytes__HumanMeta 1.58E-55B9 turquoise_M9_Oligodendrocyte__CTX 3.84E-29B9 Oligodendrocyte_probable__Cahoy 3.30E-26B9 tan_noChangeAD_oligo_plasmaMembrane__Blalock_AD 5.72E-24B9 Oligodendrocyte_definite__Cahoy 1.06E-21B9 turquoise_upAging_oligo__Lu_Aging 6.00E-17B9 Oligodendrocyte__ABA 1.75E-16B9 black_WhiteMatter__HumanChimp 1.62E-10B9 Neuron_probable__Cahoy 0.000145197B9 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.000560312B9 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.001101976B9 mutationMouseAndHuman__JAXdiseaseGene 0.006028567B9 black_noChangeAD_heatShockProteinActivity__Blalock_AD 0.010751472B9 yellow_noChangeAD_antigenProcessing_ribosome__Blalock_AD 0.022918274B9 green_M5_Mitochondria__HumanMeta 0.02327328B9 Schizophrenia_possible__DiseaseGenes 0.027498924B9 mutationMouseOrHumanOrBoth__JAXdiseaseGene 0.036757234B9 red_upAD_transferase_oncogenesis__Blalock_AD 0.041547969B10 turquoise_Cerebellum__HumanChimp 0.005620641B10 Neuron_probable__Cahoy 0.007397917B10 Neuron_definite__Cahoy 0.023937762B10 Somatic__MitochondrialType 0.038223396B11 Neuron_probable__Cahoy 7.27E-25B11 Autism_associated_module_M12__Voineagu 5.37E-14B11 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 5.55E-10B11 DownWithAlzheimers_Blalock__ADvsCT_inCA1 3.08E-09B11 green_M10_GlutamatergicSynapticFunction__CTX 1.16E-07B11 Neuron_definite__Cahoy 2.25E-07B11 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 8.51E-07B11 pink_downAD_synapticTransmission__Blalock_AD 2.03E-06B11 green_M5_Mitochondria__HumanMeta 1.11E-05B11 turquoise_M9_Oligodendrocyte__CTX 1.48E-05B11 black_M1_PvalbInterneurons__HumanMeta 5.12E-05

B11 Autism_differential_splicing_events__Voineagu 8.04E-05B11 UpWithAlzheimers_Liang__ADvsCT_inCA1 0.000126033B11 PresynapticCompartmentProteins_Morciano__MO 0.000190743B11 blue_Cortex__HumanChimp 0.000500401B11 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.000688854B11 brown_M15_Astrocyte__CTX 0.000753956B11 turquoise_Cerebellum__HumanChimp 0.000930925B11 yellow_M18__CTX 0.001348441B11 DownWithAlzheimers_Liang__ADvsCT_inCA1 0.001698088B11 greenyellow_M6_GlutatmatergicSynapse__HumanMeta 0.002278618B11 Autism_susceptability_genes_from_Pinto_et_al_2010__Voineagu 0.003531192B11 brown_Cortex__HumanChimp 0.003962339B11 Schizophrenia_possible__DiseaseGenes 0.004038522B11 CA3specific_Ginsberg__CA1vsCA3 0.004432689B11 pink_M14_GlutamatergicSynapticFunction__CTX 0.006893006B11 greenyellow_downAD_ionAndCalciumTransport__Blalock_AD 0.008859831B11 blue_downAging_mitochondria_synapse__Lu_Aging 0.010016311B11 magenta_downAD_synapticTransmission__Blalock_AD 0.011694009B11 Neuron__ABA 0.012288273B11 ER_Golgi_vesicles_Foster__MO 0.016353719B11 CA3specific_GorLorT__CA1vsCA3 0.016952627B11 midnightblue_pyramidalNeurons_Layers5&6/basolateralAmygdala__Sugino/Winden 0.022109402B11 red_LGN_interneurons__Sugino/Winden 0.023057778B11 UpWithAlzheimers_Colangelo__ADvsCT_inCA1 0.023188874B11 Cytoplasm_Foster__MO 0.023942373B11 blue_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)__Sugino/Winden 0.025424311B11 pink_glutamatergicNeurons__Sugino/Winden 0.025424311B11 GlutamatergicNeuronsInMouseCortex_Sugino__MO 0.032237086B11 red_M11_Neuron__HumanMeta 0.032358772B11 tan_M13_Neuron__HumanMeta 0.04121267B12 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.001802274B12 yellow_M15_unknown__MouseMeta 0.010597535B12 CA3specific_Newrzella__CA1vsCA3 0.023218967B12 Cytoplasm_Foster__MO 0.023897051B12 GABAergicNeuronsInMouseCortex_Sugino__MO 0.024161944B12 red_ACCandCaudate__HumanChimp 0.035210707B13 Astrocyte_probable__Cahoy 0.0002178B13 turquoise_upAging_oligo__Lu_Aging 0.00157263B13 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.011389194B13 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.019573115B13 turquoise_M14_Nucleus__MouseMeta 0.037103211B13 Neuron_probable__Cahoy 0.037343368B13 yellow_M15_unknown__HumanMeta 0.049206791

B14 brown_M3_Astrocytes__HumanMeta 2.39E-22B14 Astrocyte_probable__Cahoy 2.22E-21B14 brown_M15_Astrocyte__CTX 4.42E-15B14 UpWithAlzheimers_Blalock__ADvsCT_inCA1 8.64E-13B14 brown_upAging_copperHomeostatisMT1__Lu_Aging 3.02E-08B14 turquoise_upAging_oligo__Lu_Aging 2.50E-06B14 red_ACCandCaudate__HumanChimp 1.35E-05B14 yellow_noChangeAD_antigenProcessing_ribosome__Blalock_AD 6.92E-05B14 Astrocyte_definite__Cahoy 0.000198071B14 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.002750209B14 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.003188772B14 GABAergicNeuronsInMouseCortex_Sugino__MO 0.005035245B14 Schizophrenia_possible__DiseaseGenes 0.006165077B14 Oligodendrocyte_probable__Cahoy 0.006692685B14 upInFrontalCortex__EarlyAD 0.006858316B14 blue_M2_Oligodendrocytes__HumanMeta 0.019132271B14 magenta_M8_Microglia(Type2)__HumanMeta 0.020365635B14 Neuron_probable__Cahoy 0.026067959B14 turquoise_downAD_intracellularTransport_cytoskeleton__Blalock_AD 0.028087903B14 CA1specific_Newrzella__CA1vsCA3 0.028535993B14 Cytoplasm_Foster__MO 0.031643296B14 Oligodendrocyte_definite__Cahoy 0.04035133B14 yellow_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)/LGN__Sugino/Winden 0.046921313B15 turquoise_Cerebellum__HumanChimp 0.005937128B15 powderblue_M13_Neurogenesis__CTX 0.019588728B16 cyan_M4_Mitochondria__MouseMeta 2.31E-20B16 cyan_M4_Mitochondria__HumanMeta 1.64E-09B16 Mitochondria_Foster__MO 9.87E-07B16 salmon_M12_Ribosome__MouseMeta 2.16E-05B16 green_M5_Mitochondria__MouseMeta 0.000187805B16 honeydew_M7_Mitochondria__CTX 0.000230416B16 DownWithAlzheimers_Liang__ADvsCT_inCA1 0.000677442B16 turquoise_downAD_intracellularTransport_cytoskeleton__Blalock_AD 0.003273358B16 blue_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)__Sugino/Winden 0.009587641B16 brown_downAD_mitochondrion__Blalock_AD 0.011982942B16 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.026512561B16 turquoise_M14_Nucleus__HumanMeta 0.026634048B16 blue_downAging_mitochondria_synapse__Lu_Aging 0.028425827B16 Somatic__MitochondrialType 0.028700452B16 green_M5_Mitochondria__HumanMeta 0.030890462B16 Cytoplasm_Foster__MO 0.047060267B17 turquoise_M14_Nucleus__HumanMeta 0.000242701B17 Neuron_probable__Cahoy 0.011636891

B17 mutationMouseOrHumanOrBoth__JAXdiseaseGene 0.011676588B17 brown_M3_Astrocytes__HumanMeta 0.024654252B17 Oligodendrocyte_probable__Cahoy 0.028075822B18 CA1specific_Newrzella__CA1vsCA3 0.035466058B19 UpWithAlzheimers_Blalock__ADvsCT_inCA1 4.49E-06B19 Autism_susceptability_genes_from_Pinto_et_al_2010__Voineagu 0.00217276B19 green_M10_GlutamatergicSynapticFunction__CTX 0.002245613B19 red_upAD_transferase_oncogenesis__Blalock_AD 0.002719132B19 black_M11__CTX 0.003600437B19 turquoise_M14_Nucleus__HumanMeta 0.004930264B19 turquoise_Cerebellum__HumanChimp 0.010430019B19 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.012920068B19 blue_downAging_mitochondria_synapse__Lu_Aging 0.022026878B19 turquoise_downAD_intracellularTransport_cytoskeleton__Blalock_AD 0.029966277B19 lightcyan_M7_unknownHumanSpecific__HumanMeta 0.039091558B19 brown_Cortex__HumanChimp 0.039320888B19 red_M19__CTX 0.042664619B19 pink_M14_GlutamatergicSynapticFunction__CTX 0.047535576B20 turquoise_M14_Nucleus__HumanMeta 6.01E-07B20 UpWithAlzheimers_Liang__ADvsCT_inCA1 2.00E-05B20 green_M10_GlutamatergicSynapticFunction__CTX 2.51E-05B20 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 4.19E-05B20 Neuron_probable__Cahoy 0.000316384B20 pink_M14_GlutamatergicSynapticFunction__CTX 0.001005627B20 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.002039955B20 green_M5_Mitochondria__HumanMeta 0.003292041B20 turquoise_M9_Oligodendrocyte__CTX 0.004802972B20 Alzgene_2+_26Mar08__MO 0.004970853B20 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.005876936B20 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.009047412B20 Neuron_definite__Cahoy 0.010251034B20 yellow_Caudate__HumanChimp 0.013084793B20 Schizophrenia_possible__DiseaseGenes 0.021399984B20 red_M19__CTX 0.033512551B21 DownWithAlzheimers_Liang__ADvsCT_inCA1 4.84E-05B21 Mitochondria_Foster__MO 0.000109606B21 salmon_M12_Ribosome__MouseMeta 0.00028057B21 Somatic__MitochondrialType 0.010472908B21 green_M5_Mitochondria__MouseMeta 0.013395248B21 cyan_M4_Mitochondria__MouseMeta 0.020336853B21 red_M11_Neuron__HumanMeta 0.024032177B21 mutationHuman__JAXdiseaseGene 0.025054889B21 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.031341211

B21 green_M5_Mitochondria__HumanMeta 0.035537198B21 red_LGN_interneurons__Sugino/Winden 0.043383182B21 Neuron_probable__Cahoy 0.048471122B22 Neuron_probable__Cahoy 0.006900777B22 turquoise_Cerebellum__HumanChimp 0.0069497B22 Cytoplasm_Foster__MO 0.007255924B22 Somatic__MitochondrialType 0.029552621B22 Golgi_Foster__MO 0.04365974B22 ER_Golgi_vesicles_Foster__MO 0.044036107B22 mutationHuman__JAXdiseaseGene 0.048334452B23 turquoise_Cerebellum__HumanChimp 1.35E-09B23 DownWithAlzheimers_Liang__ADvsCT_inCA1 0.003046198B23 yellow_M18__CTX 0.010356661B23 DownWithAlzheimers_Blalock__ADvsCT_inCA1 0.018529372B23 tan_M12_Hypoxia__CTX 0.034679125B23 Up_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.036934267B23 orange_Interneurons_Cingulate(Cck+)/Somatosensory(Cck+)/LGN__Sugino/Winden 0.039714713B23 red_M19__CTX 0.041176315B24 Neuron_probable__Cahoy 3.74E-17B24 brown_Cortex__HumanChimp 3.22E-09B24 tan_M13_Neuron__HumanMeta 1.38E-08B24 salmon_M8__CTX 2.71E-08B24 DownWithAlzheimers_Blalock__ADvsCT_inCA1 5.30E-08B24 blue_downAging_mitochondria_synapse__Lu_Aging 1.48E-06B24 Neuron_definite__Cahoy 2.18E-06B24 magenta_downAD_synapticTransmission__Blalock_AD 4.50E-06B24 Schizophrenia_possible__DiseaseGenes 1.61E-05B24 greenyellow_downAD_ionAndCalciumTransport__Blalock_AD 3.63E-05B24 Neuron__ABA 7.52E-05B24 pink_downAD_synapticTransmission__Blalock_AD 8.09E-05B24 DownWithAlzheimers_Liang__ADvsCT_inCA1 0.000100271B24 green_M5_Mitochondria__HumanMeta 0.000116838B24 downInHippocampus__EarlyAD 0.000601454B24 turquoise_M9_Oligodendrocyte__CTX 0.000766153B24 midnightblue_pyramidalNeurons_Layers5&6/basolateralAmygdala__Sugino/Winden 0.001114769B24 turquoise_Cerebellum__HumanChimp 0.001421918B24 blue_Cortex__HumanChimp 0.002783132B24 CA3specific_Newrzella__CA1vsCA3 0.003945276B24 CA1specific_Newrzella__CA1vsCA3 0.004965649B24 GlutamatergicNeuronsInMouseCortex_Sugino__MO 0.007018338B24 yellow_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)/LGN__Sugino/Winden 0.007056778B24 green_M10_GlutamatergicSynapticFunction__CTX 0.008139831B24 black_M1_PvalbInterneurons__HumanMeta 0.019739182

B24 turquoise_M14_Nucleus__MouseMeta 0.022049233B24 SZGene_2+_26Mar08__MO 0.024950491B24 blue_M16_Neuron__CTX 0.028014508B24 greenyellow_M6_GlutatmatergicSynapse__HumanMeta 0.028052079B24 Autism_associated_module_M12__Voineagu 0.030200035B24 purple_downAD_synapticTransmission__Blalock_AD 0.030506775B24 Schizophrenia_probable__DiseaseGenes 0.032753078B24 turquoise_CingulateNeurons(allTypes)/Layer5__Sugino/Winden 0.039906341B24 brown_downAD_mitochondrion__Blalock_AD 0.043490876B24 Parkinson_possible__DiseaseGenes 0.044677926B25 Neuron_probable__Cahoy 0.000238862B25 Oligodendrocyte_probable__Cahoy 0.000754381B25 DownWithAlzheimers_Blalock__ADvsCT_inCA1 0.009889347B25 salmon_M8__CTX 0.015272694B25 black_M1_PvalbInterneurons__HumanMeta 0.019739182B25 greenyellow_M6_GlutatmatergicSynapse__MouseMeta 0.020644398B25 purple_downAD_synapticTransmission__Blalock_AD 0.030506775B25 orange_M5_Microglia(Type2)__CTX 0.033071094B25 pink_downAD_synapticTransmission__Blalock_AD 0.034841239B25 Neuron_definite__Cahoy 0.036243402B25 blue_Cortex__HumanChimp 0.04004534B25 Autism_differential_splicing_events__Voineagu 0.042029941B25 CA3specific_Ginsberg__CA1vsCA3 0.049915996B26 yellow_M18__CTX 4.84E-06B26 turquoise_M14_Nucleus__MouseMeta 1.64E-05B26 DownWithAlzheimers_Blalock__ADvsCT_inCA1 9.48E-05B26 blue_M16_Neuron__CTX 0.001410027B26 red_upAD_transferase_oncogenesis__Blalock_AD 0.012123401B26 Recycling_endosome_TGN_Foster__MO 0.016054139B26 black_pyramidalNeurons_Hippocampus/Amygdala__Sugino/Winden 0.019264525B26 green_CortexAndCerebellum__HumanChimp 0.021904911B26 DownWithAlzheimers_Liang__ADvsCT_inCA1 0.021970461B26 red_M11_Neuron__HumanMeta 0.022311754B26 purple_downAD_synapticTransmission__Blalock_AD 0.022530787B26 brown_downAD_mitochondrion__Blalock_AD 0.028254567B26 Neuron_probable__Cahoy 0.032319293B26 GABAergicNeuronsInMouseCortex_Sugino__MO 0.041399535B26 brown_pyramidalNeurons_Layer5/basolateralAmygdala__Sugino/Winden 0.042387645B26 blue_downAging_mitochondria_synapse__Lu_Aging 0.047617726B27 pink_M10_Microglia(Type1)__HumanMeta 6.17E-17B27 upInFrontalCortex__EarlyAD 5.35E-10B27 purple_M4_Microglia(Type1)__CTX 6.56E-07B27 upMGactivagtion_GSE1910__MicrogialMarkers 0.009834117

B27 CA1specific_Lein__CA1vsCA3 0.012471284B27 upMacrophageAndMGactivagtion_GSE1910__MicrogialMarkers 0.012471284B27 orange_M5_Microglia(Type2)__CTX 0.02280374B27 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.031059825B27 yellow_M18__CTX 0.037257767B27 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.04386929B28 DownWithAlzheimers_Blalock__ADvsCT_inCA1 0.000350879B28 Choroid plexus__ABA 0.001910502B28 Oligodendrocyte_probable__Cahoy 0.008725777B28 Autism_differential_expression_across_at_least_one_comparison__Voineagu 0.015764866B28 turquoise_M14_Nucleus__HumanMeta 0.022979596B29 mutationMouseOrHumanOrBoth__JAXdiseaseGene 6.48E-09B29 mutationMouse__JAXdiseaseGene 1.55E-06B29 mutationHuman__JAXdiseaseGene 3.23E-05B29 upMGactivagtion_GSE1910__MicrogialMarkers 0.000261151B29 magenta_M8_Microglia(Type2)__HumanMeta 0.000822554B29 Choroid plexus__ABA 0.001782866B29 mutationMouseAndHuman__JAXdiseaseGene 0.001857953B29 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.002032947B29 Parkinson_possible__DiseaseGenes 0.005568815B29 upMacrophageAndMGactivagtion_GSE1910__MicrogialMarkers 0.011613017B29 Oligodendrocyte_definite__Cahoy 0.022415992B29 Alzheimer_possible__DiseaseGenes 0.030021218B29 pink_M10_Microglia(Type1)__HumanMeta 0.039798356B30 Neuron_probable__Cahoy 1.80E-12B30 GlutamatergicNeuronsInMouseCortex_Sugino__MO 2.64E-06B30 Neuron_definite__Cahoy 0.000116161B30 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.000341715B30 green_glutamatergicNeurons__Sugino/Winden 0.000510848B30 brown_Cortex__HumanChimp 0.003370615B30 UpWithAlzheimers_Liang__ADvsCT_inCA1 0.013982584B30 yellow_M18__CTX 0.015280051B30 red_M19__CTX 0.016519167B30 yellow_Interneurons_Hippocampus(Sst+)/Cingulate(Pvalb+)/LGN__Sugino/Winden 0.023629245B30 pink_glutamatergicNeurons__Sugino/Winden 0.027950496B30 tan_M13_Neuron__MouseMeta 0.029922647B30 CA3specific_Lein__CA1vsCA3 0.030139143B31 yellow_M15_unknown__MouseMeta 0.0007122B31 lightcyan_M7_unknownHumanSpecific__HumanMeta 0.013286343B31 brown_downAD_mitochondrion__Blalock_AD 0.016933924B31 green_M5_Mitochondria__MouseMeta 0.020238635B31 Down_CD40_stimulation_in_MG_AitGhezala__MicrogialMarkers 0.027608758B31 brown_pyramidalNeurons_Layer5/basolateralAmygdala__Sugino/Winden 0.027905173

B31 UpWithAlzheimers_Blalock__ADvsCT_inCA1 0.044685525B32 downActivationMicroglia_3treatments_Thomas__MicrogialMarkers 0.004378897B32 tan_M13_Neuron__HumanMeta 0.010235887B32 tan_M13_Neuron__MouseMeta 0.021036847B32 Autism_susceptability_genes_from_Pinto_et_al_2010__Voineagu 0.030109777B33 Synaptic__MitochondrialType 0.002819473B33 CA1specific_Newrzella__CA1vsCA3 0.006931656B33 cyan_M4_Mitochondria__MouseMeta 0.00903566B33 Astrocyte_probable__Cahoy 0.040133541B34 purple_pyramidalNeurons_Layers5&6/basolateralAmygdala__Sugino/Winden 0.005069215B34 Parkinsons_probable__DiseaseGenes 0.005640082B34 Autism_differential_splicing_events__Voineagu 0.007626828B34 purple_downAD_synapticTransmission__Blalock_AD 0.007691816B34 Endoplasmic_Reticulum_Foster__MO 0.01043485B34 green_M5_Mitochondria__HumanMeta 0.011528218B34 Parkinson_possible__DiseaseGenes 0.028089812B34 blue_downAD_metalIonTransport_glycoprotein__Blalock_AD 0.038472109B34 upWithABeta_MGactivation_GSE772__MicrogialMarkers 0.043513794B34 pink_M14_GlutamatergicSynapticFunction__CTX 0.047210692B35 turquoise_upAging_oligo__Lu_Aging 0.022298162B35 Astrocyte_probable__Cahoy 0.025314809B36 brown_downAD_mitochondrion__Blalock_AD 5.70E-05B36 DownWithAlzheimers_Liang__ADvsCT_inCA1 0.011748255B36 cyan_M4_Mitochondria__HumanMeta 0.021411573B36 magenta_M8_Microglia(Type2)__MouseMeta 0.034798146B36 yellow_M18__CTX 0.036126128B37 turquoise_Cerebellum__HumanChimp 0.000164547B37 mutationMouseOrHumanOrBoth__JAXdiseaseGene 0.000675421B37 mutationMouse__JAXdiseaseGene 0.001975698B37 Schizophrenia_possible__DiseaseGenes 0.002126765B37 mutationMouseAndHuman__JAXdiseaseGene 0.014678811B37 red_LGN_interneurons__Sugino/Winden 0.016486704B37 lightyellow_telencephalicInterneurons__Sugino/Winden 0.021473697B38 yellow_Caudate__HumanChimp 1.74E-09B38 CA1specific_Ginsberg__CA1vsCA3 0.000419652B38 Schizophrenia_possible__DiseaseGenes 0.001547394B38 Parkinson_possible__DiseaseGenes 0.002236854B38 Parkinsons_probable__DiseaseGenes 0.003647525B38 lightcyan_M7_unknownHumanSpecific__HumanMeta 0.005161029B38 orange_Interneurons_Cingulate(Cck+)/Somatosensory(Cck+)/LGN__Sugino/Winden 0.009325617B38 Neuron_probable__Cahoy 0.010489744B38 Neuron_definite__Cahoy 0.011048465B38 Alzgene_2+_26Mar08__MO 0.025908874

B38 CA1specific_GorLorT__CA1vsCA3 0.026580138B38 SZGene_2+_26Mar08__MO 0.035926563B38 tan_M13_Neuron__HumanMeta 0.036691341B39 turquoise_CingulateNeurons(allTypes)/Layer5__Sugino/Winden 0.002523029B39 turquoise_Cerebellum__HumanChimp 0.022468087B39 ER_Golgi_vesicles_Foster__MO 0.040916279B39 red_M11_Neuron__HumanMeta 0.045891288

*P values are Bonferonni corrected