· web viewparticipated in graduate recruiting weekend(s) (2014) hosted a workshop and visited...
TRANSCRIPT
Department of Chemistry and BiochemistryAnnual Report for 2014
Scholarship Total of 41 Publications:
1. B. Du2, S. P. Haddad, A. Leuk, W. C. Scott, G. N. Saari, L. A. Kristofco, K. A. Connors, C. Rash1, J. B. Rasmussen, C. K. Chambliss, and B. W. Brooks*, “Bioaccumulation and trophic dilution of human pharmaceuticals across trophic levels of an effluent-dependent wadeable stream,” Philosophical Trans. B 2014 369 (1656), article no. 20140058.
2. D. Olaitan, B. Zekavat, B. Dhungana1, W. C. Hockaday, C. K. Chambliss, and T. Solouki*, “Analysis of volatile organic compound mixtures using radio-frequency ionization/mass spectrometry,” Analytical Methods 2014, 6, 4982-4987.
3. D. Watkins*, K. O. Winemiller, M. A. Mora, B. Du2, C. K. Chambliss, B. W. Brooks, and D. Phalen, “Assessment of mosquitofish, Gambusia affins, health indicators in relation to domestic wastewater discharges in suburbs of Houston, USA,” Bull. Environ. Contam. Toxicol. 2014, 93, 13-18.
4. P. D. Hazelton, B. Du2, S. P. Haddad, A. K. Fritts, C. K. Chambliss, B. W. Brooks, and R. B. Bringolf, “Chronic fluoxetine exposure alters movement and burrowing in adult freshwater mussels,” Aquatic Toxicol. 2014, 151, 27-35.
5. S. Franzellitti*, S. Buratti, M. Capolupo, B. Du2, S. P. Haddad, C. K. Chambliss, B. W. Brooks, and E. Fabbri, “An exploratory investigation of various modes of action and potential adverse outcomes of fluoxetine in marine mussels,” Aquatic Toxicol. 2014, 151, 14-26.
6. B. Du2*, A. E. Price, W. C. Scott, L. A. Kristofco, A. J. Ramirez, C. K. Chambliss, J. C. Yelderman, and B. W. Brooks, “Comparison of contaminants of emerging concern removal, discharge, and water quality hazards among centralized and on-site wastewater treatment system effluents receiving common wastewater influent,” Sci. Total Environ. 2014, 466-467, 976-984.
7. “Viewpoint: Amyloids, Melanins and Oxidative Stress in Melanomagenesis” Liu-Smith, F.; Poe, C.; Farmer, P.J.; Meyskens, F.L., Jr. Exper. Dermatol. 2014 online 2014/10/1.
8. “Ligand-based Photooxidations of [Ru(bpy)2(ttma)]+ and Zn(ttma)2” Bruner, B.; Walker, M. B.; Zhang, D.; Selke, M.; Ghimire, M. M. M.; Omary, M. A.; Klausmeyer, K.; Farmer, P J. Dalton Trans. 2014, 43,11548-11557.
9. Dana A. Horgen, Charles M. Garner; “Influence of the azulene ring on the enantioseparation of 1,5-diols.”, Chromatography 2014, 1, 65-74.
10.Dana A. Horgen, Kevin K. Klausmeyer, Cody Carson, Harry Shen and Charles M. Garner, “Remarkably large remote-stereocenter-induced chromatographic differences: azulenyl 1,5-diols.”, Tetrahedron Lett. 2014, 55, 128-132.
11.Facile syntheses of functionalized toll-like receptor 7 agonists”, Babatope Akinbobuyi, Matthew R. Byrd, Charles A. Chang, Mysa Nguyen, Zacharie J. Seifert, Anne-Laure Flamar, Gerard Zurawski, Katherine C. Upchurch, SangKon Oh, Stephen H. Dempsey, Thomas J Enke, John Le, Hunter J. Winstead, Jose R. Boquin, and Robert R. Kane Tetrahedron Letters, 2015, 56(2), 458-460, Published online 12/4/2014 (doi 10.1016/jtetlet.2014.11.126)
12. “Comparison of surface modification chemistries in mouse, porcine, and human islets”, Jeffrey A. SoRelle, Mazhar A. Kanak, Takeshi Itoh, Joshua M. Horton, Bashoo Naziruddin, Robert R. Kane, J. Biomed. Mater. Res. Part A 2015. Published online 5/24/14 (doi 10.1002/jbm.a.35229)
13. Kim S. J.*, Chang J., and Singh M. (2015) Peptidoglycan architecture of Gram-positive bacteria by solid-state NMR. Biochimica et Biophysica Acta (BBA)-Biomembranes, Vol. 1848 (1): 350-362.
14. Singh M., Kim S. J. Sharif S., Preobrazhenskaya M., and Schaefer J. (2015) REDOR constraints on the peptidoglycan lattice architecture of Staphylococcus aureus. Biochimica et Biophysica Acta (BBA)-Biomembranes, Vol. 1848 (1): 363-368.
15. Kim S. J., Singh M., Sharif S., and Schaefer J. (2014) Cross-link formation and peptidoglycan lattice assembly in the FemA mutant of Staphylococcus aureus. Biochemistry, Vol. 53 (9): 1420-1427.
16.H. Diez-y-Riega, D. Camejo, A. E. Rodriguez, and C. E. Manzanares, "Unsaturated hydrocarbons in the lakes of Titan: Benzene solubility in liquid ethane and methane at cryogenic temperatures " Planetary and Space Science, 99 (2014) 28-35.
17.H. Diez-y-Riega, D. Camejo, and C. E. Manzanares, "Thermal lens detection of one and two-color excitation of benzene in cryogenic liquid solutions", J. Raman Spectroscopy (accepted -under revision) (2014).
18. “Investigating the Ring Expansion Reaction of Pentaphenylborole and an Azide” Shannon A. Couchman, Trevor K. Thompson, David J. D. Wilson, Jason L. Dutton and Caleb D. Martin*, Chem. Commun., 2014, 11724-11726.
19. “Cross-Coupling Reactions Between Stable Carbenes” Cory M. Weinstein, Caleb D. Martin, Liu Liu and Guy Bertrand, Angew. Chem. Int. Ed., 2014, 53, 6550-6553.
20.Heling Zhou, Rami R. Hallac, Ramona Lopez, Rebecca Denney, Matthew T. MacDonough, Li Li, Li Liu, Edward E. Graves, Mary Lynn Trawick, Kevin G. Pinney, and Ralph P. Mason, Evaluation of tumor ischemia in response to an indole-based vascular disrupting agent using BLI and 19F MRI, American Journal of Nuclear Medicine and Molecular Imaging. Accepted for publication on Monday November 24, 2014.
21.Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values. Shi Y, Abdolvahabi A, Shaw BF. Protein Sci. 2014 Oct 23(10):1417-33.
22.Metal-ion-specific screening of charge effects in protein amide H/D exchange and the Hofmeister series. Abdolvahabi A, Gober JL, Mowery RA, Shi Y, Shaw BF. Anal. Chem. 2014 Oct 21;86(20):10303-10.
23.Detection of leukocoria using a soft fusion of expert classifiers under non-clinical settings. Rivas-Perea P, Baker E, Hamerly G, Shaw BF. BMC Ophthalmol. 2014 Sep 9;14:110.
24. Insights into the Role of the Unusual Disulfide Bond in Copper-Zinc Superoxide Dismutase. Sea K, Sohn SH, Durazo A, Sheng Y, Shaw BF, Cao X, Taylor AB, Whitson LJ, Holloway SP, Hart PJ, Cabelli DE, Gralla EB, Valentine JS. J. Biol. Chem. 2014 Nov 28. [Epub ahead of print]
25.Hee-Jeong Jang, Songyi Ham, Jesus A. I. Acapulco Jr., Yookyung Song, Soonchang Hong, Kevin L. Shuford, and Sungho Park, “Fabrication of 2D Au Nanorings with Pt Framework,” J. Am. Chem. Soc. 136, 17674-17680 (2014).
26.Paul A. Brown, Chengyong Xu, and Kevin L. Shuford, “Periodic Trends of Pnictogen Substitution into a Graphene Monovacancy: A First Principles Investigation,” Chem. Mater. 26, 5735-5744 (2014).
27.Hee-Jeong Jang, Soonchang Hong, Songyi Ham, Kevin L. Shuford, and Sungho Park, “Site-Specific Growth of a Pt Shell on Au Nanoplates: Tailoring their Surface Plasmonic Behavior,” Nanoscale 6, 7339-7345 (2014).
28.Kevin L. Shuford, “Modeling Nanoparticle Optics and Surface Enhanced Emission,” Invited Paper, AIP Conf. Proc. 1590, 168-177 (2014).
29.Harper, B., Miladi, M., Solouki, T.: Loss of Internal Backbone Carbonyls: Additional Evidence for Sequence-scrambling in Collision-induced Dissociation of y-Type Ions. Journal of the American Society for Mass Spectrometry 25(10) 1716-1729 (2014) (Impact Factor: 3.594, 2012)
30.Brantley, M., Zekavat, B., Harper, B., Mason, R., Solouki, T.: Automated Deconvolution of Overlapped Ion Mobility Profiles. Journal of the American Society for Mass Spectrometry 25(10) 1810-1819 (2014) (Impact Factor: 3.594, 2012)
31.Zekavat, B., Szulejko, J. E., LaBrecque, D., Olaitan, A. D., and Solouki, T.: Efficient Injection of Low Mass Ions into High Magnetic Field FTICR Mass Spectrometers. Rapid Commun. Mass Spectrom. 28(2) 230-8 (2014) (Impact Factor: 1.94, 2014) (Impact Factor: 2.64, 2014)
32.Birendra Dhungana, Christopher Becker, Behrooz Zekavat, Touradj Solouki, William C Hockaday, C Kevin Chambliss.: Characterization of Slow-Pyrolysis Bio-Oils by High-Resolution Mass Spectrometry and Ion Mobility Spectrometry, 12/22/2014 in press (Impact Factor: 2.73, 2014)
33.Zekavat, B., Miladi, M., Alfdeilat, A., Somogyi, A., and Solouki, T.: Evidence for Sequence Scrambling and Divergent H/D Exchange Reactions of Doubly-Charged Isobaric b Type Fragment ions. J. Am. Soc. Mass Spectrom. 25(2) 226-36 (2014) (Impact Factor: 3.594)
34.AlAsiri, S., Basit, S., Wood-Trageser, M.A., Yatsenko, S.A., Jeffries, E.P., Surti, U., Ketterer, D.M., Afzal, S., Ramzan, R., Faiyaz-Ul Haque, M., Jiang, H, Trakselis, M.A., Rajkovic, A. (2015) Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability. J. Clin. Invest., 125 (1), 258-262.
35.Wood-Trageser, M.A., Gurbuz, F., Yatsenko, S.A., Jeffries, E.P., Kotan, L.D., Surti, U., Ketterer, D.M., Matic, J., Chipkin, J., Jiang, H, Trakselis, M.A., Topaloglu, A.K., Rajkovic, A. (2014) Exome sequencing identifies MCM9 mutations in ovarian failure, short stature and chromosomal instability. Am. J. Hum. Genetics, 95 (6) 754-762.
36.Nucleic Acid Polymerases, Nucleic Acids and Molecular Biology Series, Vol. 30, Murakami, K.S. and Trakselis, M.A. (Eds.), Berlin, Germany, Springer, 2014
37.Trakselis, M.A. and Murakami, K.S. (2014) Introduction to Nucleic Acid Polymerases: Families, Themes, and Mechanisms, Nucleic Acid Polymerases, Murakami, K.S. and Trakselis, M.A. (Eds.), Berlin, Germany, Springer, Chapter 1.
38.Trakselis, M.A. and Bauer, R.J. (2014) Archaeal DNA Polymerases: Enzymatic Abilities, Coordination, and Unique Properties, Nucleic Acid Polymerases, Murakami, K.S. and Trakselis, M.A. (Eds.), Berlin, Germany, Springer, Chapter 7.
39. “Metformin Suppresses Gluconeogenesis by Inhibiting Mitochondrial Glycerophosphate Dehydrogenase” Madiraju, A. K.; Erion, D. M.; Rahimi, Y.; Zhang, X.-M.; Braddock, D. T.; Albright, R. A.; Prigaro, B. J.;Wood, J. L.; Bhanot, S.; MacDonald, M. J.; Jurczak, M. J.; Camporez, J.-P.; Lee, H.-Y.; Cline, G. W.;Samuel, V. T.; Kibbey R. G.; Shulman, G. I. Nature 2014, 510, 542.
40. “Synthetic Studies Toward the Citrinadins: Enantioselective Preparation of an Advanced Spirooxindole Intermediate” Matsumaru, T.; McCallum, M. E.; Enquist Jr., J. A.; Smith, G. M., Kong, K., Wood, J. L.Tetrahedron 2014, 70, 4089-4093.
41. “Collaborative Synthesis” Wood, J. L. Nature 2014, 509, 203 (News and Views)
Presentations
Dr. Darrin J Bellert1. 03/01-03/04: Invited talk at the Austin Symposium on Molecular Structure
and Dynamics at Dallas
Dr. C. Kevin ChamblissInvited Talks:
2. C. K. Chambliss*. “Bioaccumulation of Pharmaceuticals in Fish – What We Know and What We Don’t,” Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research, Barcelona, Spain, September 9, 2014.
3. C. K. Chambliss*, B. Du2, C. Rash1, A. Leuk, J. B. Rasmussen, and B.W. Brooks. “Bioaccumulation and Trophic Dilution of Human Pharmaceuticals in an Aquatic Food Web,” 34th International Symposium on Halogenated Persistent Organic Pollutants, Madrid, Spain, September 4, 2014.
Additional Presentations:
4. R. S. King*, R. A. Brain, J. A. Back, C. Becker1, M. V. Wright, V. Toteu Djomte1, W. C. Scott, S. R. Virgil1, B. W. Brooks, A. J. Hosmer, and C. K. Chambliss, “Effects of pulsed atrazine exposures on autotrophic community structure, biomass, and production in field-based stream mesocosms,” SETAC North America 35th Annual Meeting, Vancouver, BC, Canada, November 10, 2014 (oral).
5. K. A. Connors*, B. Du2, P. Fitzsimmons, C. K. Chambliss, J. W. Nichols, and B. W. Brooks, “Method optimization for fathead minnow (Pimephales promelas) liver S9 isolation,” SETAC North America 35th Annual Meeting, Vancouver, BC, Canada, November 13, 2014 (poster).
6. B. Du2*, S. P. Haddad, W. C. Scott, S. R. Burket, C. Breed, M. Kelly, L. Broach, B. W. Brooks, and C. K. Chambliss, “Differential trophic position accumulation of select contaminants of emerging concern in an urban bayou, Houston, Texas, USA,” SETAC North America 35th Annual Meeting, Vancouver, BC, Canada, November 11, 2014 (poster).
7. S. R. Burket*, M. V. Wright, L. F. Baker, C. K. Chambliss, R. S. King, C. W. Matson, and B. W. Brooks, “Uptake of pharmaceuticals by Corbicula fluminea in an effluent-dependent experimental stream mesocosm study,” SETAC North America 35th Annual Meeting, Vancouver, BC, Canada, November 11, 2014 (poster).
8. G. N. Saari*, B. Du2, S. P. Haddad, C. K. Chambliss, J. Corrales, and B. W. Brooks, “Influence of diltiazem on fathead minnow responses across
dissolved oxygen gradients,” SETAC North America 35th Annual Meeting, Vancouver, BC, Canada, November 11, 2014 (poster).
9. J. W. Nichols*, B. Du2, J. P. Berninger, K. A. Connors, C. K. Chambliss, R. J. Erickson, A. D. Hoffman, and B. W. Brooks, “Observed and modeled effects of pH on bioconcentration of diphenhydramine, a weakly basic pharmaceutical, in fathead minnows,” SETAC North America 35th Annual Meeting, Vancouver, BC, Canada, November 11, 2014 (oral).
Dr. Patrick J Farmer10. “The bioinorganic chemistry of HNO: the value of a different point of view”
West Texas A&M University, March 6, 2014
Poster and oral presentations by research students:
11. “Organometallic reactivity of nitroxyl donors with transition metal complexes” Del Homme, Michelle E.; Farmer, Patrick J. Abstracts of Papers, 247th ACS National Meeting & Exposition, Dallas, TX, United States, March 16-20, 2014, INOR-281.
12. “Is HNO produced from the reaction of H2S with GSNO or HNSO?” Kumar, Murugaeson; Clover, Tara; Farmer, Patrick J. Abstracts of Papers, 247th ACS National Meeting & Exposition, Dallas, TX, United States, March 16-20, 2014, INOR-226.
13. “Catalyzing the copolymerization of CO2 and cyclohexene oxide by employing a dinuclear cobalt complex” Keim, Jonathan H.; Poe, Carrie; Farmer, Patrick Abstracts of Papers, 247th ACS National Meeting & Exposition, Dallas, TX, United States, March 16-20, 2014, CHED-855.
Dr. Charles M Garner
14. American Scientific Affiliation meeting, Baylor University, November 17, 2014, “The current status of origin-of-life chemistry”.
Poster and oral presentations by research students:
15. "Novel C2-asymmetric bis-camphor phosphinine and bis-camphor phosphabarrelene ligands for asymmetric hydroformylation.", Dana A. Horgen, Charles M. Garner, Jason Bell and Kevin Klausmeyer, 247th National Meeting of the American Chemical Society, Dallas TX, March 17, 2014.
16. "Azulene-modified polysiloxane for use as a gas chromatography stationary phase", Matthew Jackson, Jason Schaffer, and Charles M. Garner, 247th National Meeting of the American Chemical Society, Dallas TX, March 17, 2014.
Dr. Bob Kane
17. Oral presentation at Keystone Conference “The Modes of Action of Vaccine Adjuvants”, October 8, Seattle WA: “Synthesis and Protein Conjugation of TLR Agonists”
Dr. Sung Joon Kim
18. The 4th International conference on Algal Biomass, Biofuels and Bioproducts. Talk titled “Acetate metabolism in Chlamydomonas reinhardtii by solution-state NMR” Santa Fe NM (16-19 June, 2014).
19. Texas Christian University, Department of Chemistry, “Lipoglycopeptide antibiotic mode of action by solid-state NMR “Fort Worth TX (April 22, 2014).
20.Poster and oral presentations by research students:
21. Chang JD, and Kim SJ.*, “Characterization of Staphylococcus aureus peptidoglycan tertiary structure by REDOR NMR” Gordon Research Conference (Bacterial Cell Surface), West Dover, VT (June, 2014).
22. Chang JD, Van der Veld NA, Nguyen A, Goodenough U, and Kim SJ.*, “Acetate metabolism in Chlamydomonas reinhardtii” The 4th International conference on Algal Biomass, Biofuels and Bioproducts, Santa Fe, NM (June, 2014).
23. Chang JD, Van der Veld NA, Nguyen A, Singh M, Goodson C, Goodenough U, and Kim SJ.*, “Acetate and carbonate metabolism in Chlamydomonas reinhardtii” The 16th International Conference on the Cell and Molecular Biology of Chlamydomonas, Santa Fe, NM (June, 2014).
24. Singh M, Goodson C, Goodenough U, and Kim SJ.*, “Carbonate metabolism in Chlamydomonas reinhardtii” The 4th International conference on Algal Biomass, Biofuels and Bioproducts, Santa Fe, NM (June, 2014).
25. Singh M, Kim SJ, Sharif S, and Schaefer J, “Peptidoglycan tertiary structure and lattice assembly of FemA a mutant of Staphylococcus aureus” The 55th Experimental Nuclear Magnetic Resonance conference, Boston, MA (March, 2014).
Dr. Kevin K KlausmeyerNone
Dr. Carlos E Manzanares
26. “Thermal Lens Detection of One and Two Photon Absorption of Benzene in Cryogenic Liquid Solutions” Carlos E. Manzanares, Helena Diez-y-Riega, David Camejo, European Conference on Nonlinear Optical Spectroscopy (ECONOS) 2014, Dole, France, May 10-15, 2014.
27. "Molecular structure determinations using near infrared absorption bands". Carlos E. Manzanares, International Diffuse Reflection Conference, Chambersburg, PA, Aug. 3-8, 2014.
28. "On axis and off axis phase shift cavity ring down spectroscopy". D. Camejo, H. Diez‐y Riega, and C.E. Manzanares, 247th American Chemical Society National Meeting, Dallas, Texas, March. 16-20, 2014.
Dr. Caleb D Martin29. “Investigating the Reactivity of Unusual Boron Compounds” Caleb D. Martin,
Mount Allison University, Sackville, NB, Canada, August 18, 2014. (Invited)
30. “Boron Diiminopyridine Complexes” Thomas Dunnam, Abigail Africa and Caleb D. Martin, Boron in the Americas XIV, Rutgers University – Newark, Newark, NJ, USA, June 2014.
31. “Conversion of a Borole to a 1,2-azaborine” Caleb D. Martin, Gordon Research Conference: Inorganic Chemistry, Biddeford, ME, USA, June 2014.
32. “Reactions of diiminopyridine ligands with boron halides” Abigail Africa and Caleb D. Martin, ACS National Meeting, Dallas, TX, USA, March 2014.
33. “Synthetic Studies of Electrophilic Carbenes and Main Group Compounds” Caleb D. Martin, Texas State San Marcos, San Marcos, TX, February 3, 2014. (Invited)
34. “Exploring the Electrophilicity of Singlet Carbenes” Caleb D. Martin, Texas Christian University, Fort Worth, TX, USA, January 30, 2014. (Invited)
35. “Phosphorus Carbene Complexes: Synthetic and Structural Studies” Caleb D. Martin, St. Edwards University, Austin, TX, USA, January 17, 2014. (Invited)
Dr. Kevin G Pinney
36.Kevin G. Pinney, invited to speak at the Summer Faculty Institute, Baylor University, June 19, 2014 from 1:30 to 2:30 PM on the topic of “Acquiring External Funding for your Research” / Invitation extended by Dr. Andy Arterbury – also led by Dr. Tom Hanks.
37.Kevin G. Pinney, “Highly Potent Benzosuberene and Dihydronaphthalene-based Inhibitors of Tubulin Assembly as Potential Payloads for Selective Delivery by Antibody-Drug Conjugates”, Applied Pharmaceutical Chemistry 2014, Drug Discovery in the 21st Century, The Boston Society (held at The Broad Institute, Cambridge, MA), March 4, 2014. (listed Dr. Mary Lynn Trawick as a co-author on the title slide)
38.Kevin G. Pinney, “Small-Molecule, Tubulin Binding, Vascular Disrupting Agents as Anti-Cancer Therapeutics”, 28th Annual Beak-Pines Organic Area Allerton Conference, Allerton Park, Monticello, IL (University of Illinois at Urbana-Champaign, IL), Saturday November 8, 2014.
39.Kevin G. Pinney, “Small-Molecule, Tubulin Binding, Vascular Disrupting Agents as Anti-Cancer Therapeutics”, Pharmacology Seminar Series, Department of Pharmacology, Baylor College of Medicine, Houston, TX, Tuesday December 9, 2014.
40.OXiGENE Pre-Clinical Research Collaborators Meeting, South San Francisco, CA, October 9, 2014
41.Collaborative Research Discussions during a visit to Baylor University by Dr. David Chaplin (CEO, OXiGENE Inc., and Visiting Research Professor, Baylor University) on February 23-26, 2014. These discussions included a visit by Dr. Clive P. Bosnyak (Chief Scientific Officer, Molecular Rebar Design LLC, Austin, TX) and members of his team associated with our growing collaboration.
42.Collaborative Research Discussions and Presentations during a visit to Baylor University by Dr. Clive P. Bosnyak (Chief Scientific Officer, Molecular Rebar Design LLC, Austin, TX), Dr. Malcolm Finlayson (Senior Scientist, Molecular Rebar Design LLC, Austin, TX) and Mr. Chad Lewis (Chief Global Strategy Officer, Molecular Rebar Design LLC, Austin, TX) on August 6, 2014.
43.Collaborative Research Working Days at Molecular Rebar Design, LLC (Austin, TX); participants included members of the Pinney Research Group and Trawick Research Group at Baylor University; October 14-15, 2014.
44.OXiGENE Pre-Clinical Research Collaborators Meeting, South San Francisco, CA, October 9, 2014
45.Antibody-Drug Conjugate Mastermind Day, Hanson-Wade, World ADC (held in conjuction with the AACR National Meeting), San Diego, CA, April 8, 2014
Poster and oral presentations by research students:
46.Tyler Goddard, Christine A. Herdman, and Tracy E. Strecker (along with faculty mentors, Kevin G. Pinney and Mary Lynn Trawick, Chemistry and Biochemistry) Title: Design and Synthesis of Benzosuberene Analogues as Potential Anti-Cancer Agents. Poster Board #63
47.Cassie Robertson, Jarrod P. Tunnell, Laxman Devkota, and Zhe Shi (along with faculty mentor, Kevin G. Pinney, Chemistry and Biochemistry) Title: Design and Synthesis of Bridge-Modified Combretastatin Analogues. Poster Board #62
48.Jesse Hilton, Samuel Odutola and Jiangli Song (along with faculty mentors, Kevin G. Pinney and Mary Lynn Trawick, Chemistry and Biochemistry) Title: Cruzain Inhibition by Thiosemicarbazones as Therapeutics for Chagas’ Disease. Poster Board #67
49.Laxman Devkota, Blake A. Winn, Tracy E. Strecker, David J. Chaplin, Mary Lynn Trawick, and Kevin G. Pinney, “Bioreductively Activatable Prodrug Conjugates (BAPCs) of Combretastatin A-1 (CA1) as Anticancer Agents Targeted Towards Tumor Hypoxia” Abstract No: MEDI 146, 247th ACS National Meeting & Exposition, March 16-20, 2014, Dallas, TX (poster presented on Sunday March 16, 2014).
50.Samuel O. Odutola, Lindse(a)y M. Jones, Jiangli Song, G. D. Kishore Kumar, Kevin G. Pinney, and Mary Lynn Trawick, “Evaluation of Inhibitors of Cruzain as Potential Therapeutics for Chagas Disease” Abstract No: BIOL 73, 247th ACS National Meeting & Exposition, March 16-20, 2014, Dallas, TX (poster presented on Sunday March 16, 2014).
51.Thomas Wittenborn, Michael Stratford, Mary Lynn Trawick, Kevin G. Pinney, David J. Chaplin, Dietmar W. Siemann, and Michael R. Horsman, “Assessment of Anti-Tumour Activity of the Cathepsin L Inhibitor KGP94”, Abstract No. 1816, American Association of Cancer Research (AACR) 104th Annual Meeting, San Diego, CA, April 5-9, 2014. Poster presented on Monday April 7, 2014.
52.H. Zhou, R. R. Hallac, R. Denney, L. Li, R. Lopez, L. Liu, E. E. Graves, M. L. Trawick, K. G. Pinney, R. P. Mason, “Evaluation of tumor oxygenation in response to an indole-based vascular disrupting agent using 19F MRI”, Proc. Joint Annual Meeting ISMRM-ESMRMB, Milan, Italy, May 2014.
53.Li Liu, Mary Lynn Trawick, Kevin G. Pinney, Ralph P. Mason, “In Vivo Comparison of Novel Vascular Disrupting Agents in Breast Cancer Using Dynamic Bioluminescence
Imaging”, World Molecular Imaging Congress (WMIC) 2014, Seoul, Korea, September 17-20, 2014.
54.Morgan S. Cooper (invited speaker), Rajendra P. Tanpure, Clinton George, David J. Chaplin, Kevin G. Pinney, and Mary Lynn Trawick. "Bioreductive Cleavage of Prodrugs of Combretastatin Analogues by NADPH Cytochrome P450 Oxidoreductase" Texas Enzyme Mechanisms Conference, The University of Texas at Austin, Austin, TX, Jan. 3-4, 2014.
55.Morgan S. Cooper, Rajendra P. Tanpure, Clinton George, David J. Chaplin, Kevin G. Pinney, and Mary Lynn Trawick (poster presentation). "Bioreductive Cleavage of Prodrugs of Combretastatin Analogues by NADPH Cytochrome P450 Oxidoreductase" Texas Enzyme Mechanisms Conference, The University of Texas at Austin, Austin, TX, Jan. 3-4, 2014.
Dr. Bryan F Shaw
56.Oregon State University, Linus Pauling Institute (Invited by Professor Joseph Beckman): “Arresting Amyloid with Coloumb’s Law”; February 20, 2014
57.Pacific University (Invited by Northwest Congress of Optometry): “Photographic Detection of Retinoblastoma”; February 22, 2014
58.Georgia Institute of Technology (Invited by Professor M.G. Finn): “Cu, Zn Superoxide Dismutase and ALS: To Charge or Not to Charge?”; September 15, 2014 (11am-12pm)
59.Georgia Institute of Technology (Invited by Professor M.G. Finn): “Can Smart phones prevent metastatic retinoblastoma in children?”; September 15, 2014 (4:30-5:30pm)
60.PopTech 2014: Rebellion (Invited by Dr. Joe Palca): “Joe Palca with inventors”; October 23, 2014; video: http://poptech.org/popcasts/joe_palca_with_inventors
61.TEDx Utica: Limitless (Invited by TEDx selection committee); “Can smartphones and Facebook help kids survive eye cancer?”; November 7, 2014, Utica, New York; video: https://www.youtube.com/watch?v=XH2Y8iKfDbQ
Selected Media Coverage of Bryan Shaw:
62.NPR Morning Edition (National): May 6, 2014; http://www.npr.org/blogs/health/2014/05/06/309003098/chemist-turns-software-developer-after-sons-cancer-diagnosis
63.NPR Morning Edition (National): May 7, 2014; http://www.npr.org/blogs/health/2014/05/07/310104315/faith-drives-a-father-to-create-a-test-for-childhood-cancer
64.NPR Morning Edition (National): August 11, 2014; http://www.npr.org/blogs/health/2014/08/11/338329842/where-we-learn-that-artificial-eyes-really-arent-round-at-all
65.NPR Morning Edition (National): October 31, 2014; http://www.npr.org/blogs/health/2014/10/31/359568507/look-here-phone-app-checks-photos-for-eye-disease
66.BBC: November 12, 2014; http://www.bbc.com/capital/specials/protection-now/health/white-eye-app-can-give-red-flag-to-eye-abnormalities_a-32-369.html
67.CBS (Dallas affiliate): May 19, 2014; http://dfw.cbslocal.com/2014/05/19/white-eye-photos-may-indicate-rare-cancer-in-children/
68.CBS (Austin affiliate): November 6, 2014; http://www.keyetv.com/news/features/special/stories/app-helps-detect-cancer-hiding-plain-sight-205.shtml
69.Numerous CBS, ABC and NBC affiliate spin-offs of (6) and (7) in large markets (e.g., Philadelphia, Boston, San Antonio)
70.Fast Company: July 10, 2014; http://www.fastcoexist.com/3032018/diagnosing-cancer-by-scanning-the-family-photo-album-for-white-eyes
71.Wikipedia: http://en.wikipedia.org/wiki/Bryan_Shaw_%28chemist%29
72.Waco Tribune: November 2, 2014; http://www.wacotrib.com/news/higher_education/eye-cancer-in-children-baylor-profs-develop-an-app-for/article_ae135c4b-59bd-5ee3-86f6-cf97a387d10b.html
73.Spokesman Review: September 23, 2014; http://www.spokesman.com/stories/2014/sep/23/app-aims-to-alert-parents-to-sign-of-rare-eye-canc/
Dr. Kevin L Shuford74.Kevin L. Shuford, “Nanoscale Modeling and Simulation: Fundamental Optics and
Energy Applications,” Department of Chemistry, University of Florida, Gainesville FL, December 2014.
75.Kevin L. Shuford, “Nanoscale Modeling and Simulation: Fundamental Optics and Energy Applications,” Department of Chemistry and Biochemistry, Florida State University, Tallahassee FL, December 2014
76.Kevin L. Shuford, “Plasmonic Nanostructures for Sensing and Energy Applications,” Energy, Materials, and Nanotechnology Meeting, Orlando FL, November 2014.
77.Kevin L. Shuford, “Nanoscale Modeling and Simulation: Fundamental Optics and Energy Applications,” Department of Chemistry, University of Central Florida, Orlando FL, November 2014.
78.Kevin L. Shuford, “Nanoscale Modeling and Simulation: Fundamental Optics and Energy Applications,” Department of Physics and Energy Science, University of Colorado at Colorado Springs, Colorado Springs CO, October 2014.
79.Kevin L. Shuford, “What Modeling Can Tell You about Why Nano is Different,” Department of Chemistry and Biochemistry, St. Edward’s University, Austin TX, October 2014.
80.Kevin L. Shuford, “Nanoscale Modeling and Simulation: Fundamental Optics and Energy Applications,” Department of Chemistry, University of North Carolina at Charlotte, Charlotte NC, September 2014.
81.Kevin L. Shuford, “What Modeling Can Tell You about Why Nano is Different,” Department of Chemistry, Texas Lutheran University, Seguin TX, September 2014.
82.Kevin L. Shuford, “What Modeling Can Tell You about Why Nano is Different,” Department of Chemistry, Trinity University, San Antonio TX, September 2014.
83.Kevin L. Shuford, “Nanoscale Modeling and Simulation: Fundamental Optics and Energy Applications,” Department of Chemistry and Biochemistry, Texas Tech University, Lubbock TX, April 2014.
84.Kevin L. Shuford, “Suppression of Quenching in Strongly Coupled Nanodimers,” Austin Symposium on Molecular Structure and Dynamics at Dallas, Dallas TX, March 2014.
85.Kevin L. Shuford, “Suppression of Quenching in Strongly Coupled Nanodimers,” American Chemical Society Meeting, Dallas TX, March 2014.
Poster and oral presentations by research students:
86.Sungho Park and Kevin L. Shuford*, “Optical Properties of Complex Nanorod Architectures,” American Chemical Society Meeting, Dallas TX, March 2014.
87.Olga Samoylova, Emvia Calixte, and Kevin L. Shuford*, “Interfacial Structure and Confinement Effects of Aqueous Electrolytes in Carbon Pores,” American Chemical Society Meeting, Dallas TX, March 2014.
88.Dustin Buller* and Kevin L. Shuford, “The Effects of Alcohol on Ion Transport Across Neural Trans-membrane Channels:A Molecular Dynamics Study,” Undergraduate Research and Scholarly Achievement (URSA) Presentation, Baylor University, Waco TX, April 2014.
89.Paul Brown*, Chengyong Xu, and Kevin L. Shuford, “Modification of the Electronic Properties of Graphene via Molecular Adsorption and Lattice Substitution,” American Chemical Society Meeting, Dallas TX, March 2014.
90.Paul Brown*, Chengyong Xu, and Kevin L. Shuford, “Periodic Trends of Pnictogen Substitution into a Graphene Monovacancy: A First Principles Investigation,” ACS Southwest Regional Meeting, Fort Worth TX, November 2014.
91.Olga N. Samoylova, Emvia I. Calixte*, and Kevin L. Shuford, “Molecular Dynamics Simulations of Ion Transport through Carbon Nanotube Channels,” ACS Southwest Regional Meeting, Fort Worth TX, November 2014.
92.Cody Scruggs* and Kevin L. Shuford, “Tensile and Compressive Loading of Class 5 Amyloid Fibrils using MD Simulations,” Undergraduate Research and Scholarly Achievement (URSA) Presentation, Baylor University, Waco TX, April 2014.
93.Paul Brown*, Chengyong Xu, and Kevin L. Shuford, “Substitutional Effects of Pnictides in a Monolayer Graphene Sheet: A Density Functional Study,” American Chemical Society Meeting, Dallas TX, March 2014.
94.EmviaCalixte*, Olga Samoylova, and Kevin L. Shuford, “Molecular Dynamics Study on Confinement Effects of Aqueous Electrolytes with Graphene-based Electrodes towards the Development of Enhanced Supercapacitor Materials,” American Chemical Society Meeting, Dallas TX, March 2014.
Dr. Touradj Solouki
95.Harper, B.; Brantley, M.; Pettit, M.; Solouki, T. “Spectrometry Instruments.” Proceedings of the 62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD.
96.Harper, B.; Neumann, E. K.; Olaitan, A. D.; Solouki, T. “Sequence-scrambling in Collision-induced Dissociation of Oligonucleotides.” Proceedings of the 62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD.
97.Zekavat, B.; Harper, B.; Brantley, M.; Pettit, M. E.; Solouki, T. “Use of Multivariate Curve Resolution and Ion Mobility-Mass Spectrometry for Isomer Differentiation.” Proceedings of the 62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD.
98.Olaitan, A. D.; Zekavat, B.; Solouki, T. “Ionization Mechanism in Radio-Frequency Ionization (RFI).”Proceedings of the 62nd ASMS Conference on Mass Spectrometry and Allied Topics, 2014, Baltimore, MD.
99.Harper, B.; Zekavat, B.; Brantley, M.; Pettit, M.; Solouki, T. “Energy Resolved Ion Mobility Deconvolution of Isobaric Compounds.” Proceedings of the 62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD.
100. Miladi, M.; Olaitan, A. D.; Zekavat, B.; Lochridge, J.; Solouki, T.; Effect of Metal Ion and Neutral Reagent Type on Gas-Phase Adduct Formation.” Proceedings of the 62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD.
101. Matthew R. Brantley, M. R; Zekavat, B.; Olaitan, A. D.; Solouki, T. “Inexpensive, Programmable, and Modular Radio-Frequency Power Supplies for Mass Spectrometers” Pittsburgh Conference, poster presentation to be presented on 3-11-2015, New Orleans, LA.
102. Harper, B.; Lochridge, J.; Solouki, T. “Spray Pump Ionization Mass Spectrometry of Pharmaceutical, Peptide, and Protein Ions.” Pittsburgh Conference, poster presentation to be presented on 3-11-2015, New Orleans, LA.
103. Olaitan, A. D.; Zekavat, B.; Solouki, T. “Electron Generation in Radio Frequency Ionization” Pittsburgh Conference, poster presentation to be presented on 3-11-2015, New Orleans, LA.
104. Pettit, M. E.; Harper, B.; Brantley, M. R.; Solouki, T. “Collision-Energy Resolved Ion Mobility Deconvolution of a Ternary Isomeric Mixture” Pittsburgh Conference, Oral Presentations, poster presentation to be presented on 3-11-2015, New Orleans, LA.
105. Harper, B.; Neumann, E. K.; Solouki, T. “Improving Sequence Coverage of Ion Mobility Unresolved Peptide Isomers Using Chemometric Data Deconvolution” Pittsburgh Conference, oral presentation to be presented on 3-11-2015, New Orleans, LA.
106. Reviewed tens of proposals (two NSF Panel Reviews in May 5 (virtual) and August 19), six tenure/annual promotions (internal and external/international), and seven papers for various journals.
107. National ACS Meeting “Ionization, chemometric, & derivatization methods for analysis of complex petroleum and biofuel samples by MS & IMS” MS and Related Technologies for Energy & Fuels, March 18, 2014, Dallas, TX.
108. University of Texas at Arlington, Department of Chemistry & Biochemistry, Department, “Multidimensional Mass and Ion Mobility Spectrometry Beyond m/z Measurements: Structural Characterization of Macromolecules, March 21, Arlington, TX.
109. Center for Astrophysics, Space Physics & Engineering Research (CASPER), “Radiofrequency Ionization Coupled with Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (RFI FT-ICR MS)”, April 4, 2014, Waco, TX.
110. Beach Tree Labs Annual Meeting, “Multidimensional Analysis Of Streptolysin O”, September 21, 2014 Rensselaerville, NY
Dr. Michael A. Trakselis
111. Trakselis, M.A. (2015) Evolved ssDNA Interactions with Hexameric Helicases. Zing Nucleic Acids Meeting, Cancun, Mexico.
112. Trakselis, M.A. (2014) Title Detection of a Supraholoenzyme DNA Polymerase Complex for Coupled DNA Replication and Lesion Bypass. ACS Southwestern Regional Meeting (SWRM), Ft. Worth, TX, U.S.A.
113. Trakselis, M.A. (2014) Title TBD: Northeastern University, Chemistry and Chemical Biology Department Colloquium
Poster and oral presentations by research students:114. Carney, S.M., Graham, B.W., Tao, Y., Schauer, G.W., Marshall, A.G., Young,
N.L., Leuba, S. Trakselis, M.A. (2015) Evolved ssDNA Conformations with Hexameric Helicases Facilitate DNA Unwinding. 24th Biannual Enzyme Mechanisms Conference, Galveston, TX, U.S.A.
Dr. Mary Lynn Trawick
115. Laxman Devkota, Blake A. Winn, Tracy E. Strecker, David J. Chaplin, Mary Lynn Trawick, and Kevin G. Pinney, “Bioreductively Activatable Prodrug Conjugates (BAPCs) of Combretastatin A-1 (CA1) as Anticancer Agents Targeted Towards
Tumor Hypoxia” Abstract No: MEDI 146, 247th ACS National Meeting & Exposition, March 16-20, 2014, Dallas, TX (poster presented on Sunday March 16, 2014).
116. Samuel O. Odutola, Lindse(a)y M. Jones, Jiangli Song, G. D. Kishore Kumar, Kevin G. Pinney, and Mary Lynn Trawick, “Evaluation of Inhibitors of Cruzain as Potential Therapeutics for Chagas Disease” Abstract No: BIOL 73, 247th ACS National Meeting & Exposition, March 16-20, 2014, Dallas, TX (poster presented on Sunday March 16, 2014).
117. Thomas Wittenborn, Michael Stratford, Mary Lynn Trawick, Kevin G. Pinney, David J. Chaplin, Dietmar W. Siemann, and Michael R. Horsman, “Assessment of Anti-Tumour Activity of the Cathepsin L Inhibitor KGP94”, Abstract No. 1816, American Association of Cancer Research (AACR) 104th Annual Meeting, San Diego, CA, April 5-9, 2014. Poster presented on Monday April 7, 2014.
118. H. Zhou, R. R. Hallac, R. Denney, L. Li, R. Lopez, L. Liu, E. E. Graves, M. L. Trawick, K. G. Pinney, R. P. Mason, “Evaluation of tumor oxygenation in response to an indole-based vascular disrupting agent using 19F MRI”, Proc. Joint Annual Meeting ISMRM-ESMRMB, Milan, Italy, May 2014.
119. Li Liu, Mary Lynn Trawick, Kevin G. Pinney, Ralph P. Mason, “In Vivo Comparison of Novel Vascular Disrupting Agents in Breast Cancer Using Dynamic Bioluminescence Imaging”, World Molecular Imaging Congress (WMIC) 2014, Seoul, Korea, September 17-20, 2014.
120. Morgan S. Cooper (invited speaker), Rajendra P. Tanpure, Clinton George, David J. Chaplin, Kevin G. Pinney, and Mary Lynn Trawick. "Bioreductive Cleavage of Prodrugs of Combretastatin Analogues by NADPH Cytochrome P450 Oxidoreductase" Texas Enzyme Mechanisms Conference, The University of Texas at Austin, Austin, TX, Jan. 3-4, 2014.
121. Morgan S. Cooper, Rajendra P. Tanpure, Clinton George, David J. Chaplin, Kevin G. Pinney, and Mary Lynn Trawick (poster presentation). "Bioreductive Cleavage of Prodrugs of Combretastatin Analogues by NADPH Cytochrome P450 Oxidoreductase" Texas Enzyme Mechanisms Conference, The University of Texas at Austin, Austin, TX, Jan. 3-4, 2014.
122. Collaborative Research Discussions during a visit to Baylor University by Dr. David Chaplin (CEO, OXiGENE Inc., and Visiting Research Professor, Baylor University) on February 23-26, 2014. These discussions included a visit by Dr. Clive P. Bosnyak (Chief Scientific Officer, Molecular Rebar Design LLC, Austin, TX) and members of his team associated with our growing collaboration.
123. Collaborative Research Discussions and Presentations during a visit to Baylor University by Dr. Clive P. Bosnyak (Chief Scientific Officer, Molecular Rebar Design LLC, Austin, TX), Dr. Malcolm Finlayson (Senior Scientist, Molecular Rebar Design
LLC, Austin, TX) and Mr. Chad Lewis (Chief Global Strategy Officer, Molecular Rebar Design LLC, Austin, TX) on August 6, 2014.
124. Collaborative Research Working Days at Molecular Rebar Design, LLC (Austin, TX); participants included members of the Pinney Research Group and Trawick Research Group at Baylor University; October 14-15, 2014.
125. OXiGENE Pre-Clinical Research Collaborators Meeting, South San Francisco, CA, October 9, 2014(dual-listed under research presentations – section above)
Poster and oral presentations by research students:
126. Tyler Goddard, Christine A. Herdman, and Tracy E. Strecker (along with faculty mentors, Kevin G. Pinney and Mary Lynn Trawick, Chemistry and Biochemistry)
127. Title: Design and Synthesis of Benzosuberene Analogues as Potential Anti-Cancer Agents. Poster Board #63
128. Jesse Hilton, Samuel Odutola and Jiangli Song (along with faculty mentors, Kevin G. Pinney and Mary Lynn Trawick, Chemistry and Biochemistry)
129. Title: Cruzain Inhibition by Thiosemicarbazones as Therapeutics for Chagas’ Disease. Poster Board #67
Dr. John L Wood
130. University of Manchester UK (January 2014)
131. Novartis, Horsham UK (January 2014)
132. Amgen, San Francisco (January 2014)
133. University of Texas, Arlington (February 2014)
134. Nichols Medal Award Symposium New York (March 2014)
135. Stereochemistry GRC (August 2014)
136. Yale University (Wasserman Symposium Sept. 2014)
137. American Cancer Society (Waco Chapter, Oct. 2014)
138. Nanyang Technological Univ., Singapore (Oct. 2014)
139. SWRM of the ACS Fort Worth (November 2014)
Grant Proposals and Awards 56 proposals, 15 funded totalling $2,886,884
Principal Investigator Co-PI Funding
SourceAmt
RequestedAmt
Funded Title of Proposal
Darrin Bellert Welch $180,000
A Novel Approach to State Selected
Chemistry and its Application to
Catalysis
URC $4,000 $4,000
Reaction Dynamics Along Spin Surfaces
in Two-State Reactive
Mechanisms
ACS $110,000
Reactivity of Atomic and Diatomic Cations
Toward Organic Substrates; A Gas
Phase Study of Potential Reforming
Catalysts
Kevin Chambliss NSF $186,686
Collaborative Research: Towards
Manufacturing Biofuels –
Understanding the Role of Inhibitory
Compounds Generated During
Pretreatment
Syngenta $186,490 $190,000
Effect of Exposure Conditions on
Laboratory-Derived Sampling rates for
POCIS DevicesNSF $194,987 Collaborative
Research: Understanding the Role of Inhibitory
Compounds Generated During
Chemical Pretreatment of Lignocellulosic
Biomass
Patrick Farmer Welch $180,000
Reactivity Studies of Nitroxyl with Metal-
based Enzymes and Complexes
NIH $1,918,209
Cu ionophores in combination therapies for melanoma
de Mesa NSF $236,382
New Path to Success: an
extended freshman chemistry series for
at-risk students
NSF $417,557 Bioinorganic NOx reactivity
Martin, Shaw, Pinney
NSF $276,702 $241,989
MRI-Acquisition of a Bruker EMXplus
Series EPR Spectrometer
Charles Garner Welch $180,000
Simplified Access to Chelating Phosphine
Ligands
URC $2,000 $2,700
Benzoylcamphor derivatives as
nonlinear optical materials
Robert Kane CFRIP $25,000 $25,000
Islet Immunoprotection
Using Multiple Novel Surface Modifications
URC $7,500 $7,500
Synthesis and Evaluation of Novel
Immune-Ssytem Modulators'
JDRF $109,983 Functional
Modifications to Islet Surfaces
Sung Joon Kim Keck $985,05
Development of a solid-state NMR
instrument for in vivo study of intracellular
pathogens
NIH $692,500 pending Glycopeptide
complexes with bacterial cell walls
Mallinckrodt $180,000
Molecular Mechanisms of
chlamydia infection by solid-state NMR
Mizutani Foundation $68,000
Peptidoglycan Tertiary Structure by
Solid-State NMR
URC $7,500
Characterization of peptidoglycan
compositions and structures in Gram-
positive bacteria
Welch $180,000
Ultra-Fast Magic-Angle Spinning Solid-State NMR Study of
Biopolymers
Kevin Klausmeyer URSA $3,000
Coordination Complexes of Functionalized
Phosphines
Carlos Manzanares Welch $180,000
Photochemical Decomposition of
Esters and Formation of Organic Acids in
the Atmosphere
Airware, Inc. $18,155 $18,156
Near-infrared spectra of rabbit blood
samples
Caleb Martin Welch $180,000 $180,000
New Powerful Lewis Acids as Metal-Free
Catalysts
ACS $180,000Redox-Active Ligand Assisted Catalysis in
Boron Complexes
KevinPinney Trawick CPRIT $900,000 $900,000
Targeting Hypoxia in Breast Cancer with
Highly Potent Small-Molecule Anticancer
Prodrugs
Trawick CPRIT $200,000
Antibody Drug-Conjugates for
Delivery of Potent Tubulin Binding
Anticancer Agents
Welch $180,000 Mechanistic Studies on the Cysteine
Proteases Cathepsin L and Cathepsin K
Trawick DOD/CDMRP $537,378
Targeting Hypoxia in Breast Cancer with
Highly Potent Small-Molecule Anticancer
Prodrugs in Combination with Radiation Therapy
Trawick NIH $417,928
Antibody-Drug Conjugates for
Delivery of Potent Tubulin Binding
Anticancer Agentof Potent Tubulin
Binding Anticancer Antibody-Drug Conjugates for
Delivery
Trawick NIH $3,037,218
The Development of Novel Cathepsin L and K Inhibitors as
Anti-metastatic Agents
Trawick CPRIT $649,502
Tentative Title (will likely change): Investigations
Directed Towards the Validation of
Cathepsin L as a Target for Anti-
Metastatic Therapeutic Intervention
OXIGENE, INC $225,000 $225,000
Enhanced Synthetic Chemistry to Support
Cathepsin L Drug Discovery and Tumor
Selected Delivery Strategies for Highly
Potent Anticancer Agents
Trawick NIH $422,109 R-21 Special: Antibody-Drug Conjugates for
Delivery of Potent
Tubulin Binding Anticancer Agents
CPRIT $200,000
Unique Highly Discrete Carbon
Nanotubes (CNTs) for Tumor-Selective Delivery of Highly
Potent Dual-Mechanistic
Anticancer Agents
Trawick OXIGENE, INC $100,000 $100,000
Small-Molecule Anticancer Agents: Design, Synthesis,
and Biological Evaluation
Bryan Shaw Welch $180,000 $180,000
Asparagine deamidation in motor neurons: a molecular clock or a ticking time
bomb?
URSA $4,746 $4,746 Charge regulation in metalloproteins
F32 Post Doc
Fellowship NIH $60000
Synthesis and Evaluation of Charge Boosting Compounds to Treat Amyotrophic
Lateral Sclerosis
Kevin Shuford Dreyfus $75,000
Modeling Electrochemical
Interfaces
Welch $180,000
Electronic Properties and Surface
Chemistry of Doped Graphene
NSF $363,598
Modeling Physical and Chemical Processes at Liquid/Solid
Interfaces for Electrical Energy
Storage
DOE $369,828 Modeling
Electrochemical Interfaces
Touradj Solouki Chambliss NSF $476,725 MRI: Development of
Next Generation High
Resolution Imaging Mass Spectrometry
for Single Cell Anaysis
Welch $180,000
Experimental and Computational Studies of H/D
Exchange Reaction Kinetics: Gas-phse Chemical Probes
Farmer NSF $684,793 $684,793
IDBR: Type A – Ultrahigh Spatial Resolution Sub-
organelle Molecular Mass Spectrometry
Imaging Using Liquid Metal Ion Beam Desorption and Radiofrequency
Ionization
NIH $602,710
Novel Multiplexed Conformational
Analyses and Non-Covalent Interaction Mapping for Early
Detection and Monitoring of Ovarian
Cancer
NSF $365,935
Instrument Development: Smart
Radio Frequency Ionization Systems for Highly Sensitive and Programmable Multidimensional
Chemical Measurements
NIH $265,935
Early Detection of Ovarian Cancer
Through Multiplexed Conformational
Analyses and Non-Covalent Interaction Mappings in Cells
NIH $79,022 Cell and Tissue Imaging by Ambient
Laser Ablation Sampling and High Resolution Mass
Spectrometry
Michael Trakselis
American Cancer Society
$123,394 $123,000
Mechanism of DNA Polymerase
Switching During Replication to Bypass
Lesions
NSF $859,759
Evolved DNA contacts required for hexameric helicase
unwinding
Mary Lynn Trawick
UT Austin - CPRIT $80,000
Hypnoxis-derived antineoplastics:
Multitargeted, ADMA-optimized rooperol
analogs
John Wood
F32 Post Doc
Fellowship NIH $159,906
Desymmetrization of Meso Compounds in
Natural Product Synthesis: Total
Synthesis of Mollolide A
Undergraduate Program Dr. C. Alton Hassell, UPD2014 Fall enrollment of 580 undergraduate majors
In 2014 Chemistry & Biochemistry had 22 tenure-track faculty (18 of which are research active) and 7 non-tenure track faculty. The 2013 Fall SCH/FTEF (Student Course Hours/ Full-Time Equivalent Faculty) was 426, up from 313 in 2009, and much higher than the College of Arts & Sciences’ average of 225. Our Fall SCH has increased from 8,822 in 2009 to 11,941 in 2014, due to the larger percentage of premedical entering freshman. Our high teaching load is attributable to large service courses for students in Biology, Health Sciences, Psychology & Neuroscience, Engineering and University Scholars.
Promotions
Dr. Marie Maricel de Mesa from Lecturer to Senior LecturerDr. Riz Klausmeyer, Director of Living Learning Center
Faculty Additions
Dr. Paul Zinke, Lecturer in Organic Chemistry
University 1000 TeachingAlton HassellMaricel de MesaThomas McGrath
Teaching HonorsDe Mesa Baylor Professor Award 2014 (picked by student athletes)Klausmeyer, R Baylor Professor Award 2014 (picked by student athletes)Hassell Baylor Professor Award 2014 (picked by student athletes)
Engaged and experiential learning
Undergraduate Research Course Enrollments Spring 2014
Course Section Professor Enrollment
CHE 1V98 01 Bellert 102 Chambliss 103 Farmer 5
06 Hassell 109 Kane 113 Manzanares 114 Martin 316 Pinney 519 Trawick 220 Wood 121 Shuford 1
CHE 2V98 01 Kim 102 Klausmeyer 203 Chambliss 104 Garner 205 Pinney 1
CHE 4V98 01 Bellert 203 Farmer 204 Garner 305 Kane 306 Kim 108 Klausmeyer 111 Pinney 112 Shaw 315 Trawick 1
Undergraduate Research Course Enrollments SU 2014
CHE 1V98 03 Farmer 304 Garner 106 Kane 511 Pinney 315 Trawick 117 Jones 1
CHE 2V98 01 Martin 103 Farmer 1
CHE 4V98 03 Farmer 1
Undergraduate Research Enrollment Fall 2014
CHE 1V98 03 Farmer 304 Garner 307 Kim 110 Martin 211 Pinney 715 Trawick 117 Trakselis 2
CHE 2V98 01 Bellert 102 Pinney 203 Kane 104 Farmer 105 Trawick 1
CHE 4V98 02 Chambliss 103 Farmer 104 Garner 405 Kane 107 Klausmeyer 210 Pinney 111 Shaw 112 Shuford 213 Solouki 1
Other types of engaged learning
Fall 2014Alton Hassell – CHA 1088-B34 Major Sciences 18 studentsTom McGrath – CHA 1088-C9 Major Sciences 18 studentsMaria de Mesa – CHA 1088-TRL General Sciences 18 students
Honors SectionsSpring 2014 CHE 1302 Pennington 10 students
CHE 1405H1Hassell 1 studentsCHE 1405H2Hassell 2 students
Fall 2014 CHE 1301 Pennington 27 studentsCHE 1405H1Hassell 2 studentsCHE 1405H2Hassell 1 studentsCHE 3331 Garner 20 students
MinimesterSummer 2014 CHE 1302-M1 McGrath 13 students
General Education Courses for Major for 2014s
Spring Summer FallCourse Faculty
Enroll. Course Faculty
Enroll.
Course Faculty
Enroll.
1101 Lahousse 296 1302 M1 McGrath 13 1101 Rabbe 9671102 Rabbe 590 1102 Lahousse 2371301 Olson 81 1101 Lahousse 18 1301 Gipson 87
Gipson 76 1102 Rabbe 32 Olson 289Olson 27 1301 Olson 16 Pennington 93Shuford 47 Hodson 12 Hodson 242Martin 48 1302 McGrath 22 Klausmeyer 164Hodson 101 Hodson 24 Hassell 135
1302 McGrath 231 2216 Hassell 8 Castleberry 178Castleberry 175 3238 George 48 Rabbe 80Hassell 41 3331 Jones, L 31 1302 McGrath 177Hodson 150 Jones, J 8 Castleberry 74Klausmeyer 37 3332 Jones,L 58 Pennington 10 Jones, J 18 2216 Solouki 93
4302Pennington 4
2216 Rabbe 77 4341 Jonklaas 12 3238 George 212 Kane 1
3238 George 291 3331 Zinke 1693331 Jones, J 60 Jones, J 45
Jones, L 196 George 803332 Jones, L 102 Kame 33
Garner 71 Hodson 50
Kane 19 Klausmeyer, R 47
Pinney 72 Garner 20George 93 3332 Jones, J 121Jones, J 51 Wood 48
4001 Hassell 76 4001 Hassell 11
4125 Kim, J 26 4125Manzanares 48
4128 Bellert 14 4127 Bellert 244141 Sevcik 23 4141 Sevcik 594142 Sevcik 52 4142 Sevcik 21
4151 Hassell 11 4151Klausmeyer, K 15
Kim, S-K 13 Solouki 15
de Mesa 4 Olson 15Bellert 9 4207 McGrath 26
4217 Ramirez 29 4307 Farmer 154237 Garner 27 4321 Bellert 22
4302 Pennington 39 4327Manzanares 55
4316 Chambliss 48 4332 Kane 164322 Bellert 15 4341 Trakselis 23
4327Manzanares 7 Jonklaas 102
4341 Jonklaas 75 Shaw 60Kim, J 13 4342 Trawick 28Sevcik 22
4342 Kim, J 80
Graduate Program Dr. Charles M Garner, GPD2014 Fall enrollment of 57 graduate students
As a research active department, we continue our push towards Carnegie VHR status expectations while attempting to balance teaching loads with research demands of faculty. From June 2014 to February 2015, research expenditures totaled $1,558,517 from 22 active grants or contracts which include nationally competitive funding from the DOD, DOE, and American Cancer Soc. for Asst. Profs. Shaw, Shuford and Trakselis, from the NSF for Profs. Shaw, Farmer and Solouki, from the NIH/NCI for Profs. Pinney and Trawick and from CPRIT for Profs. Pinney, Trawick and Wood. Additional funding from private sources was obtained by Profs. Chambliss, Martin, Shaw, Solouki, Trawick and Pinney.
Degrees awarded
4 Ph.D. 1 MS Thesis 7 MS Non-Thesis
Faculty Additions
Dr. Michael Trakselis, Assistant Professor in Biochemistry
Departmental Highlights
Summer Research Experiences for Undergraduates (REU) program funded by the National Science Foundation, to run 2015-17, $224K, to fully support eight external students each summer.
A dramatic upgrade in departmental NMR instrumentation (addition of automated 400 and 600 MHz instruments) funded by CPRIT grant to Prof. Wood.
Hiring of two new faculty: Dr. Elyssia Gallagher, Asst. Prof. of Analytical Chemistry, coming from NIST and Dr. Daniel Romo, Schotts Professor of Organic Chemistry coming from Texas A&M University.
Service Activities by Faculty
Dr. Darrin J BellertDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Please list (1) administrative assignments, (2) committee activities; (3) student advising activities, including service as undergraduate and graduate adviser, major advising during registration, orientation activities, student organization advising, recruitment and retention activities:Invitation to Excellence (02/01/14)High School, Middle School and Regional Science Fair Judge (02/25/14)Department Graduate Recruiting Weekend (02/28/14-03/01/14)Annual Instrumentation Workshop (09/26/14-09/27/14)ACS Undergraduate Student Affiliates AdvisorChair of the Instrumentation Committee (2014)Selection Committee for Outstanding Professors (2014)
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member of St. Jerome Catholic Church in HewittActive in Cub/Boy Scout leadership (a ministry of St. Jerome Catholic Church)Article Reviewer for J. Phys. Chem.
Dr. Vanessa CastleberryDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Served on the textbook selection committee during the spring of 2014. Attended all publisher presentations, tried out many of their online products, and implemented a couple in my classes as a trial run to see what students responded to best. Read the three books that were on the final list.Served as an academic undergraduate advisor for BS Biochemistry majors (30 students). Attended the advisor training in August. Faculty mentor for Baylor Quidditch Association and BU Meds.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member of AAAS. Member of ACS. Member of AOS. Member of the KWBU CAC (serving in the role of secretary)
Dr. C. Kevin ChamblissDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Member of 3 University Committees and 4 Departmental Committees – University Committees: VHR, Radiation Safety, ad-hoc Selection of Graduate Student Teaching Award in the Sciences;
Department Committees: Graduate Committee, Tenure and Promotion Committee, Gooch-Stephens Committee, Search Committee for a Junior Analytical Faculty Member Served on the TIE3S Advisory Board and was appointed TIE3S Graduate Program Director June 1, 2014.Served on a dean-appointed committee to review and revise sections of ProFuturA&S, the strategic plan for the College of Arts and Sciences
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Invited Session Chair (w/ Dr. Ethel Eljarrat), “Pseudo-POPs – Non-persistent but persistently in the environment,” 34th International Symposium on Halogenated Persistent Organic Pollutants, Madrid, Spain, September 3, 2014.Manuscript reviewer for multiple peer-reviewed journalsMember of the Arena Team at Bosque County Cowboy Church (BGCT affiliate), Meridian, TX
Dr. Maria Maricel de MesaDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Faculty host in a table of prospective students in Invitation to Excellence both spring and fallFaculty host in Kaleidoscope (Feb 28)Chemistry major advising during registrationPre-Health Committee MemberAttendance to Pre-health Subcommittee MeetingCommittee Report Writing for Pre-med and Pre-dent studentsInterviewed student candidates for Baylor2Baylor program (recruitment activity)Meeting of prospective students and their parents during campus visits Hosted the visit of 40 AVID high school kids from Connally, Moody and Oglesby ISD Education Service Center Region 12 Faculty usher in commencement ceremonyBaylor greeter for student transfereesParticipation in Parent’s weekendAttendance at Faculty meetingsAttendance at Women in Science and Engineering Brown Bag LunchWriting of recommendation letters for students applying to medical school, scholarships, internship, etc.Participation in Cultural Connection sponsored by the diversity committee (Jan 31)Attendance to NSNA Teacher Appreciation DinnerAttendance to Inaugural Veteran Recognition ReceptionAttendance to FCS Nutrition Science review for re-accreditation (Accreditation Council for Education of Nutrition and Dietetics)Attendance to Seminar for Advisors of Baylor Student Organizations
Attendance to Baylor Science Collaborative Meeting Chi Alpha Christian Fellowship Faculty Advisor Attendance to Meeting with School of Nursing Re: development of a chemistry course for the nursing curriculum
Dr. Patrick J FarmerDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Department: de facto member of all Chemistry & Biochemistry committees, including Safety Committee,Ran searches for Junior Biochemistry, Inorganic and Analytical Faculty, Organic Lecturer and Senior Organic positions. Organized a Summer Undergraduate Research Program for Chemistry & Biochemistry, June-August 2014College of Arts & Sciences: Biology Chair Search, Pro Futuris Themes 2, , Microscopy Facility Manager Search Committee. Organized institutional proposal preparation for HHMI for the Sustaining Excellence competition focused on student retention and persistence in STEM fields. University: Carnegie VHR committee, Invitation to Excellence recruiting
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member First United Methodist Church, active in the praise band, part-time Sunday School teaching. Reviewed NSF, PRF and NIH proposals in field, 2 this year (have declined many due to high workload)Reviewed submissions to J. Amer. Chem. Soc., Inorg. Chem., J. Inorganic Biochemistry
Dr. Charles M GarnerDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Director of graduate program (beginning fall 2007).Graduate Advisor to ~ 55 students.Organized Graduate Recruiting Weekend, February 28-March 1, 2014.Graduate recruiting at American Chemical Society national meeting, Dallas, TX, March 16; and at the Southwest Regional meeting of the American Chemical Society, Ft. Worth, TX, November7, 2014.Conducted orientation for new graduate students (with K. Humphrey and Kevin Chambliss), August 21, 2014.Member of URSA (undergraduate research and scholarly achievement) Steering Committee.NSF virtual panel for review of REU proposals, December 11-12, 2014Invitation to excellence, January 31 and November 24th, 2014.Advanced Instrumentation Workshop, September 26, 2014 (NMR section, with Mike Brown of Bruker, Inc.).
Attended Council for Undergraduate Research meeting, Washington D.C., June 29-July 1, 2014.Organic chemistry review for exit exam, March 21st and November 7th.Primary guide for tours of BSB chemistry areas.Chemistry Departmental Water Marshall.Alcohol Curator for Sciences Building.Supervisor of the fifth-floor glass shop.Administrator of ChemBioOffice software site license.Keeper of department's standardized ACS exams.Instrumentation Committee.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member, American Chemical Society and Organic Chemistry DivisionESL teacher and member, Calvary Baptist Church.
Dr. Stephen L GipsonDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Director of Undergraduate Advising for CHE dept.Trained and assisted other departmental advisors.Advisor to B.S. chemistry majors. This included individual advisement sessions with 91 different students in the spring and summer for fall and 131+ in the fall for spring registration.University Premedical/Predental Advisory CommitteeFreshman Summer Orientation Advisor, summer 2014 - advised and registered 102 incoming freshmen and transfersConducted peer review of teaching for Maria de Mesa (applying for senior lecturer) during Summer-2 term.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Park Lake Drive Baptist Church, memberFormosan Christian Church of Dallas, participant
Dr. C. Alton HassellDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Director of Undergraduate Programs
DepartmentalUndergraduate Affairs Chemistry Awards CommitteeChemistry Scholarship Committee
UniversityGraduation co-Chief Marshal (Spring, Summer, Fall)(30 hours per ceremony)Public Exercises Committee
AdvisingBA Chemistry AdvisorKappa Omega Tau sponsor (5 hours per week)Chemistry Honors Society sponsor Interviewer for Baylor 2 Baylor Program
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Graded AP Chemistry examsColumbus Avenue Baptist Church (Deacon, Choir member and officer)
Dr. Bruce HodsonDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Dept. of Chem. and Biochem. Library Committee; UG Affairs and Awards CommitteeFaculty Advisor to the Baylor Rock Climbing Team, attending weekly practice, and both regional and national level competitions. Student Advising: 48 (BSc Biochemistry)Greeter at Freshman Orientation during the summer
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Profession membership of the American Chemical Society (ACS), Regular member at the 7th and James Baptist Church, visiting Fellowship Church Grapevine.
Dr. Jesse W JonesDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
National Baptist Congress of Christian Education (109th Session), Instructor, course: “People of Color in the Bible”, Dallas, TX, June 16-20, 2014.Local Church Activities. Member of the Trustee Board, Deacon, Sunday School Teacher and Dean of the Christian Leadership School at the Good Street Baptist Church.Advisory Board, Member, Circle Ten Council, BSAMember, Board of Directors, Museum of African American Life and CultureAmerican Chemical Society
American Institute of Chemist, FellowNational Institute of ScienceBeta Kappa Chi Honor Society The Society of the Sigma XiNational Organization for Black Chemist and Chemical Engineers
Dr. Marc Devan JonklaasDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
I also served as a faculty partner for a particular floor on Brooks Hall (from Fall 2013 to Spring 2014). As faculty partner, I participated in events with these students (e.g. attending dinners at Brooks cafeteria, a frozen yogurt social, etc.) as a way for students to get to know Baylor faculty better. This also included a special dinner function for the group at the Brooks faculty master’s (Dr. Rishi Sriram’s) residence.I served as a Biochemistry Advisor for the Dept. of Chemistry & Biochemistry and advised numerous students over the course of 2014.Although not officially recorded as “service,” I also wrote numerous letters of recommendation for students applying to graduate or health professions schools (especially Pharm., Medical and Dental schools) as many of them require at least one recommendation from a Biochemistry professor.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
My wife and I have been active and involved members of Antioch Community Church (ACC) in Waco and attend Sunday services at ACC and also participate in small group (cell group) meetings associated with the church.My wife and I served as Directors of a weekend Children’s Conference at All People’s Church in San Diego California in Spring 2014: This involved coordinating and running worship and programs for about 105 children ages 3-12.
Dr. Bob KaneDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Director, Institute for Biomedical StudiesDirector/Organizer, Advanced Instrumentation Workshop.Graduate Committee: a number of BMS and Chem & Biochem grad studentsSponsor - Vietnamese Student Association.Scholars Week Moderator
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Adjunct Investigator, Baylor Institute for Immunology Research, Baylor Health Care System
Chair, Conflict of Interest Committee, Baylor Research Inst. (Baylor Health Care System)Grant reviewer –NSF (2 SBIR Panels).Manuscript Referee: Bioconjugate Chemistry, Journal of the American Chemical Society, Biomaterials, Tetrahedron Letters,Phytochemistry.
Dr. Sung Joon KimDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Erin Foster, Honors Advanced ReadingElizabeth Luper, Honors Advanced ReadingAngeline Nguyen, Honors Advanced ReadingDavid Song, Special Research ProblemRebecca Ramirez, Special Research ProblemAlex Guinn, Special Research ProblemPanayotis Apokremiotis, Special Research ProblemAmbreea Warren, Special Research ProblemChemistry Graduate Student Admission CommitteeHonors Thesis Committees: Sara Ji Soo Park, Elizabeth Luper, Angeline NguyenMS Committee: Nicole SolidaPh.D. Committee: Sara Schlesinger, Eun-Jeong Yu
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member of Korean United Methodist Church since 2011. Have served as a Sunday college group bible study leader in 2013 and am currently serving as a Director of Education.American Society for Microbiology
Dr. Kevin KlausmeyerDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Associate Chair for Graduate AffairsGraduate Affairs Committee, Instrumentation CommitteeParticipated in I2E Fall 2014X-ray portion of the Advanced Instrumentation Workshop
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member St. Louis Catholic Church, Waco, TXThird Degree Member of the Knights of ColumbusReviewed manuscripts for several different journals
Dr. Carlos E ManzanaresDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Baylor University Committees:Laser Safety CommitteeChemistry Department Committees:Departmental Safety CommitteeInstrumentation Committee (undergraduate)Long Range Planning CommitteePromotion CommitteeTenure CommitteeLibrary Committee
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member of Saint Jerome Catholic ChurchBaylor University Chapter Co-Adviser for the ALPHA LAMBDA DELTA Academic Honor SocietyFor the past seven years I have been in charge of recruiting and selecting judges in the areas of biology, chemistry, and physics for the: " Midway Middle School Science Fair" .Research advisor for projects involving one Midway High School student (Linda Ren). As science fair participant, she has received honors at regional and state levels.Member of the Laser Electro-Optics Technology Advisory Committee. This advisory committee works in conjunction with the Nano Technology and Semiconductor Manufacturing Technology Advisory Committees. The three advisory committees were created at TSTC to increase and improve training of personnel in these areas. The advisory committee will make recommendations to TSTC to make curriculum changes to reflect new technologies as well as changes and advances in industry related to laser and electro optics, nano, and semiconductor technologies.
Dr. Caleb D MartinDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Committee activities: Within the department I devote a significant amount of time towards serving on student evaluation committees. I evaluated all the annual inorganic division graduate student oral exams. In addition, I evaluated the graduate student seminars. In 2014, I served on two PhD defense committees (one in my division and one in the organic division).Student Advising Activities: I am the direct graduate supervisor of Thomas Dunnam and Samantha Yruegas, two PhD students in my research laboratory. In 2014, I supervised 3 undergraduates in my laboratory (Abigail Africa, Trevor Thompson and Ben Caputo). I am a supporter of minorities in science (Trevor is an African American and Abigail is a female student). Trevor’s work resulted in a publication (#2).
Recruitment and Retention: In 2014, I gave four invited seminars, three of which were at primarily undergraduate institutions. The primary goal of these visits was to recruit students into our graduate program at Baylor. I accompanied Dr. Charles Garner at the Baylor booth at the graduate recruitment session to answer the questions to potential incoming graduate students at the ACS national meeting in Dallas.The department organizes an Instrumentation Workshop each year to expose undergraduate students from small schools to facilities that they wouldn’t have access to at their institution. I coordinated a workshop for this event in my laboratory allowing the program to expand. The department is regularly hiring new faculty members and I meet with all incoming candidates and often partake in dinners. I also regularly meet with visiting speakers for our department colloquium series often taking them out to dinner or breakfast. In one case, to save the department money I had a speaker stay at my house.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Professional Association: I also served as a chair for a session at the Boron in the Americas conference in Newark, NJ (June 2014). I am a member of the American Chemical Society and the Canadian Society for Chemistry.Community Activities: I am a donor to the Baylor Bear Foundation that provides scholarship funds for Baylor’s student-athletes and supports as well as promotes the interest and welfare of Baylor Athletics. I regularly attend Football, Softball, Basketball and Baseball games to support Baylor student-athletes.I frequent the events put on by the Waco Young Professionals Organization. This organization aims to shape and promote Waco’s quality of life, attract and retain a labor force of educated young adults by establishing professional relationships, developing leaders and investing in our community. Church Service Activities: After spending a considerable amount of time searching for a new church in Waco, I have joined St. Alban’s Episcopal Church. I was confirmed into the church in October (my previous church, the United Church of Canada did not do confirmations). As a new member of the church, I have already become involved in the Men’s ministry and also the crisis cooking team who provides meals for those who are in times of need and unable to prepare meals for themselves.
Dr. Thomas McGrathDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Assisted the Undergraduate Program Director (on an ad hoc basis) with scheduling and other matters.University-Wide: University Lecturers Committee; Pre-Health Committee; Board of Prehealth Advising.Departmental: Undergraduate Affairs Committee; Library Committee; Lecturer Review Committees (De Mesa, Castleberry); Mentor (Castleberry).
Academic Advisor for B.S. Biochemistry studentsMember, Board of Prehealth AdvisingInterviewed students for Baylor to Baylor Program (January 2014) and hosted dinner at Invitation to Excellence (January 2014, October 2014).Represented the Department at Academic Convocation, April 2014.Faculty Advisor, Baylor Cricket Club.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES:
Member of the American Chemical SocietyMember of the Royal Society of Chemistry (U.K.) and Chartered ChemistMember of the British Crystallographic SocietyFaculty Advisor for Pearson’s Mastering Chemistry systemHosted several “phone-ins” with 8th grade science students at Atlas Academy, WacoActive member of Saint Jerome Catholic Church, Waco
Dr. John A OlsonDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Advising students began during the Fall term and I was responsible for about thirty students.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
ACSSaint Mathew Lutheran Church
Dr. David E PenningtonDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Prof. Pennington served as the departmental representative to the Council for Chemical Research, attended the Annual CCR Meeting In Alexandria, VA and took part in some 5 Graduate Education conference calls. The CCR Conference dovetailed with the National Academy of Science’s Workshop on Chemical Education in Washington, DC. He continues as JAMP Faculty Director supervising four JAMP students grooming four more for interviews, and interviewed 9 premedical students for the Prehealth Advisory Committee. He also served on the Prehealth Committee, the W. Dial Black Family Lectures Committee, and chaired the Departmental Library Committee. He serves as Faculty Advisor to the Baylor Texas Beta Chapter of Alpha Epsilon Delta, the National Prehealth Honor Society (completing 27 years) and serves as Regional Director of Region IV for the Society (Re-elected) , attended the 2014 National Convention in Nashville, TN where he Chaired the Regional Business Meeting. Our Chapter won Second Place for Activities & Attendance for Large Chapters in Region IV; he reviewed three Charter Applications for new AED Chapters. He
began a new role by serving on the Halley Earle Hall Advisory Board, assisted with Spring and Fall Premiers and at one Invitation to Excellence recruitment dinner. In the spring & fall he led the Inorganic Chemistry Review for the Chemistry EXIT EXAM. He is an active member of the American Chemical Society and served on the Awards Committee for the 2015 Southwest Regional Meeting. Prof. Pennington attends Seventh & James Baptist Church, where he is a Sunday school Teacher, Adult Choir member, and Deacon. Worked one day at a Habitat work sit w/church group, assisted w/CrossTies Children's Christmas Party, & w/MOW.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
A fifty year member of the American Chemical Society and Alpha Chi Sigma (the national professional society in chemistry).Attended TAAHP Annual Meeting hosted by US Southwestern School of MedicineServed as Moderator at Seventh & James Baptist Church (chairing Council Meetings & presiding at monthly business meetings).Taught an Adult Sunday School class and sang in the Adult Choir
Dr. Kevin G PinneyDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Member and co-founder of The Center for Drug Discovery (Summer 99-present).Baylor University Graduate Faculty (Full, Regular Member)Institute of Biomedical Studies (Full Faculty Member)Currently serve as Chair of the W. Dial Black Family Lectures Selection Committee, College of Arts and Sciences, (2007 – present).Chair (2014-2015), University Research Committee (URC), 2007 – present.Baylor University Committee on Intellectual Property (2012-2015).Member, Cornelia Marschall Smith Professor of the Year Selection Committee (2014-2016)Gooch-Stephens Lecture Committee Welch Chair CommitteeA total of approx. 44 letters of recommendation were written and processed on behalf of approximately 18 different (present and former) students, postdocs, and colleaguesParticipated in Graduate Recruiting Weekend(s) (2014)Hosted a Workshop and visited with Faculty and Students attending the Advanced Instrumentation Workshop (AIW) September 26-27, 2014.Participation as a faculty table representative for the Invitation to Excellence dinner on Friday January 31, 2014.Participation as a faculty table representative for the Invitation to Excellence dinner on Friday October 24, 2014.Member of the Pre-Tenure/Tenure Review Committee for Dr. Erica Bruce, Department of Environmental Science.
Invited participant in the PROFF (Preparing our Future Faculty) Workshop (Tuesday February 4, 2014) – review CV and cover letters with graduate students [Creekmore Conference Room in the Jesse H. Jones Library at Baylor University].
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Served (in 2014) as Peer Reviewer for Approximately eight (8) Manuscripts Submitted for Publication in Journals and Declined Numerous Other Review Opportunities Due to Time constraints.Served (by invitation) as the Chairperson of the Drug Delivery Section of the Cancer Chemistry Subcommittee of the 2014 American Association for Cancer Research (AACR) Program Committee (actual work done in late 2013 and early 2014).Conducted an invited grant review for the Medical Research Council in the UK, September, 2014Member of the First United Methodist Church in Waco)Attend (since mid-fall 2004) worship services on a regular basis at Antioch Community Church (Waco, TX)
Dr. Amanda Charlton SevcikDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Invitation to Excellence table host for the Chemistry Dept. 1/31/14Hosted 11:00-11:30 meeting with colloquium speaker, Dr. Yulia Sevryugina, Texas Christian University, 3/7/14Faculty Senior Reception, 4/4/14Campus visit host for prospective students and family, 4/11/14, 4/25/14ATL hosted seminar “Positive Psychology Techniques in University Teaching”, 5/6/14Student advising training, 8/18/14Biochemistry undergraduate advising (30 students), Fall 2014ASBMB Webinar on Chemistry and Biochemistry certification, report created and sent to Biochemistry faculty and Department head, 10/1/14Biochemistry Laboratory Dedication 11/1/14Baylor Parent Coffee, 11/20/14Co-designed “chemistry-themed” page in the 2014 Baylor University Press publication “Green, Gold, Baylor: A Little Bear Colors Book” 2014
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member of Calvary Baptist Church, Easter 2014Children’s Bible club at Calvary Baptist Church, 6/16/14 – 6/20/14Early Childhood Sunday school volunteer, Calvary Baptist Church, monthly throughout 2014
Meals on Wheels Volunteer for Calvary BC, daily meal preparation/organization, 12/16/14 – 1/7/14Meals on Wheels Volunteer, animal food delivery route, December 2014American Chemical Society memberAmerican Society for Biochemistry and Molecular Biology (ASBMB) member.
Dr. Bryan F ShawDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Member, graduate student admission committee.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Member, Redeemer PresbyterianTeacher, Redeemer Presbyterian Church, “Kid’s Quest Catechism”; Wednesday 5:30 pm-7 pm.Regular attendee of Redeemer Pres. Men’s bible study; Tuesday at 6-7:30 am.Faculty mentor for Reformed University Fellowship, a Baylor-approved student group.
Dr. Kevin L ShufordDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Committee Activities:Graduate committee, Department of Chemistry and BiochemistryStudent Advising Activities:Advisor for 2 postdoctoral associatesAdvisor for 3 graduate studentsAdvisor for 4 undergraduate studentsOther Department/University Service:Made a number of recruiting trips to regional colleges to promote our graduate programContributed to departmental REU proposal that was fundedMaintained departmental computational chemistry facilityParticipated in graduate student recruiting weekendOrganized/hosted workshops for Advanced Instrumentation WorkshopWrote nomination letters for Cherry Award candidate and Outstanding Staff awardApplied for BU Faculty in Residence position (interviewed but was not selected)Participated in search committees for new faculty, graduate seminar program, colloquium activities, divisional summer orals
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Reviewer for journal articles (Journal of Physical Chemistry, ACS Photonics, Journal of Computational Chemistry)
Reviewer for proposals (Department of Energy – Computational and Theoretical Chemistry, also Condensed PhasedInterfacial Molecular Sciences; National Science Foundation – Macro, Supra, and Nanochemistry)Member of American Chemical Society and Materials Research SocietyAttended Woodway First United Methodist Church. Participant in local and international outreach. Active in youth and adult social events
Dr. Touradj SoloukiDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
I have been involved in student recruitment and I am a member of the following committees:Instrumentation (Department), Wilson Award Committee (University), Scholarly Communication Task Force Representatives Committee, and I am a member of the analytical division committee as well as numerous graduate student committees. Also, I have participated in student training and presentations of AIW last three years. I have been the chair/co-chair of committees for (a) full professor promotion and (b) new assistant professor hire. I have advised several undergraduate students (please see table III)In 2014 I advised 2 postdocs, 6 graduate students, and 3 undergraduate students.
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Current Membership/Professional Association:Member of the American Society for Mass SpectrometryMember of the American Chemical Society. CHURCH SERVICE ACTIVITIESWe (my wife, Sabina, and I) are members of the St. John United Church of Christ (Robinson, TX 76706). At our church, we are members of the following committees: 1- Pastoral Relations, 2- All-Church Meals, 3-Budget, and 4- Special Projects. We also look for opportunities to participate in our community events (e.g., Mission Waco; St. John UCC special events to raise funds to support local community events).
Dr. Michael TrakselisDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Graduate Student Curriculum
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Book Coeditor: Nucleic Acid Polymerases, Springer, 2014Editorial Boards: International Scholarly Research Notices (ISRN) (2014-present)
New Journal of Science (2013-present)ISRN Molecular Biology (2010-2014)Ad-hoc Manuscript Reviewer: Nature, Science, ACS Chemical Biology, Nature Chemical Biology, Journal of Biological Chemistry, Biochemistry, Journal of Bacteriology, Journal of Molecular Biology, Research and Reports in Biology, EMBO, Molecular Microbiology, Archaea, Encyclopedia of Catalysis, Nucleic Acids Enzymes, FEBS Letters, Molecular and Cellular Biology, Springer Books, Molecular Biology Reports, Molecular Genetics & Genomic Medicine. Frontiers in Microbiology, Nature Scientific Reports, Nature CommunicationsFaculty of 1000 (F1000) - Faculty Member – Biocatalysis Section (2013 – Current)Grant Review Committee Member: American Cancer Society DNA Mechanisms in Cancer (DMC) (2013-2017)
Dr. Mary Lynn TrawickDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Member of The Center for Drug Discovery (Summer 99-present).Baylor University Graduate Faculty (Full, Regular Member)Institute of Biomedical Studies (Full Faculty Member)Committee to evaluate Summer Sabbatical Leave Requests Currently serve on the W. Dial Black Family Lectures Selection Committee, Institutional Biosafety CommitteeBaylor University Committee on Intellectual Property Undergraduate Affairs CommitteeCollaborative Activity with the Baylor Biomedical Research InstituteParticipated in Graduate Recruiting Weekend(s) (2014)Participated in Instrumentation Workshop (2014)Numerous letters of recommendation were written and processed on behalf of approximately 10 different (present and former) students Dissertation Committee Member for a number of graduate students in our Department, BMS and the Department of Environmental ScienceOther Service Activities on the Campus of Baylor UniversityMember of the Pre-Tenure/Tenure Review Committee for Dr. Erica Bruce, Department of Environmental Science
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Served (in 2014) as Ad Hoc Peer Reviewer for Manuscripts Submitted for Publication in Journals Including: ChemMedChem, Bioorganic Medicinal Chemistry Letters, ChemComm, Journal of Cellular Biochemistry, and Journal of Enzyme Inhibition and Medicinal Chemistry
Member of St. Paul’s Episcopal Church, Waco, TX
Dr. John L WoodDEPARTMENT AND UNIVERSITY SERVICE ACTIVITIES:
Baylor, Chemistry and Biochemistry Seminar Committee, Fall 2014Baylor, Chemistry and Biochemistry Gooch-Stephens Committee
PROFESSIONAL ASSOCIATION, COMMUNITY, AND CHURCH SERVICE ACTIVITIES
Editor for the Americas, Tetrahedron Letters (I handled 920 Manuscripts in 2014)Editor, Organic Syntheses (In addition to making decisions our laboratory checks 2-3 procedures/year)Co-Chair, Tetrahedron Symposium, London (This symposium hosted approximately 640 delegates)Co-Chair, Tetrahedron Symposium Asia Edition, Singapore (This symposium hosted 550 delegates)Coach, Science Olympiad Preston Middle SchoolMember, St. Alban’s Episcopal Church, Waco TX. Elected to the Vestry, three-year term to begin in 2015, supported the Crisis Cooking Team, Provided Food to the Baylor Episcopal Student Center, Participated in midweek youth ministry
Guest Lecturers, Colloquia, and Seminars
CHE 5050 Chemistry Colloquium, Spring 2014
Hosts: Dr. Charles M Garner and Dr. Kevin L Shuford
Speaker
Chris Beaudry, Oregon State UniversityShih-Yuan Liu, Boston CollegeRoberto de la Salud Bea, Rhodes CollegeAndrew Rappe, Univ. of PennsylvaniaM. G. Finn, Georgia TechYulia Sevryugina, Texas ChristianKarl Hale, Queen’s University, Belfast, IrelandAdrian Roitberg, Univ. of FloridaMarty Pomper, John Hopkins UniversityGrant Jensen, Cal TechDaniel Romo, Texas A&M UniversityGraeme Henkelman, Univ. of TexasPurneudu (Sandy) Dasgupta, UT, ArlingtonDr. Eunsuk Kim, Brown University Eric Ferreira, Colorado State University
CHE 5050 Chemistry Colloquium, Fall 2014
Hosts: Dr. John Wood and Dr. Caleb Martin
Speaker
Viresh Rawal, University of ChicagoChris Bielawski, University of Texas - AustinPaul Cheong, Oregon StateStephen Gray, Argonne National Laboratory Brian McNaughton, Colorado State UniversityTheodore Betley, Harvard UniversityAndrew Evans, Queen’s University, CanadaRichmond Sarpong, University of California - BerkeleySteve Westcott, Mount Allison UniversityZach Tonzetich, University of Texas – San AntonioChris Vanderwal, University of California – IrvinePaul Hergenrother, University of Illinois at Urbana-ChampaignChristopher Cummins, Massachusetts Institute of TechnologySunil David, University of Kansas
Stone Symposium/Gooch-StephensDue to hosting the Southwest Regional Meeting of the ACS, being held here in Waco in November of 2013, the Stone Symposium and Gooch-Stephens lectures were not held in 2014.
Fall 2014 Advanced Instrumentation WorkshopOur AIW Workshop received 45 Applications. 39 Student Participants were accepted - (23 males/16 female). We had 10 Faculty attend the workshop also. We had 5 declines and one person submitted 2 apps listing different areas of research interest. Our Participants represented 13 Colleges/Universities.
Summer Undergraduate Research ProgramOur Summer Undergraduate Research Program was funded for the last 2 summers (2012-13) by our College of Arts and Sciences and Chemistry & Biochemistry Dept. In fall 2014 we are fortunate to be a recipient of the National Science Foundation – Research Experiences for Undergraduates grant.
In the spirit of continuing our summer research effort, each faculty who had undergraduate students working under them continued supervising their students, and we composed a program. We had 16 Baylor and Bio-medical students and 1 Non-BU student from the University of Maine. We also had 1 high school student phased into our activities. We still met for 10-weeks of research, had weekly lunch-seminar meeting on research and advanced techniques, and a special seminar addressing research ethics and career opportunities in science. Our Non-BU student received a stipend, was provided housing and a portion of his travel, covered by Dr. Touradj Solouki.
Societies and Associations Dr. David Pennington represents the department each year at the annual meeting of the Council for Chemical Research. Annual surveys and data are provided for the Council for Chemical Research, American Chemical Society and SACS which the department maintains memberships.
Development Funds 2014Development funds contributed to the Department of Chemistry in 2014 totaled $325,328.
(Scholarship funds, Memorial Scholarship funds, Endowment funds, Foundation funds, personal donations).
Our large donations ($1000+) were:Mr. & Mrs. Robert L. Cagle 4/30/2014 $100,000.00
Robert A. Welch Foundation Attn: Norbert Dittrich
Funding to Caleb Martin 9/10/2014 $60,000.00
Robert A. Welch Foundation Attn: Norbert Dittrich
Funding to Bryan Shaw 9/10/2014 $60,000.00
The Honorable Jennifer Walker Elfrod and Mr.
Funding to Biochemistry Lab 7/22/2014 $20,656.80
Pine Street Foundation
Funding to Touradj Solouki 7/2/2014 $20,000.00
Robert A. Welch Foundation Attn: Norbert Dittrich
Funding to Caleb Martin 6/5/2014 $15,000.00
Robert A. Welch Foundation Attn: Norbert Dittrich
Funding to Caleb Martin 6/5/2014 $15,000.00
Swint Enterprises Attn: Richard Swint 1/21/2014 $10,000.00
Organic Syntheses Inc. Attn: Carl R. Johnson, Treasur
Funding to John Wood 12/10/2014 $3,000.00
Dow Chemical Company Foundation 2/25/2014 $2,000.00
Dr. Robert E. Graves 6/23/2014 $2,000.00
Mr. & Mrs. Gerald D. Tiner 9/19/2014 $2,000.00
Ms. Margaret Jane Davis 1/22/2014 $1,200.00
Drs. Lawrence & Frances Hartley Jr. 1/6/2014 $1,000.00
Dr. & Mrs. Kevin G. Pinney 12/22/2014 $1,000.00
Staffing Changes
Dr. Meike Lahousse was hired as Freshman Lab coordinator.
Changes in Facilities & EquipmentDuring 2014 the Department of Chemistry and Biochemistry purchased over $2.8
million worth of equipment and instrumentation. The bulk of this amount was composed of three large purchases, the first consisting of 3 high performance, digital NMR spectrometers totaling nearly $1.5 million dollars, funding for this came from the CPRIT grant. These spectrometers are available for department wide use. The second large purchase was for a CM3 reaction screening robotic system as part of the new CPRIT laboratory for Drs. Wood and Romo, this totaled $632K. The third large purchase was for an NSF funded EPR spectrometer system with a total cost of over $340K, this instrument is for department wide use. In addition to these three main purchases there were several other pieces of equipment purchased either as replacements for existing instruments or new additions for either the teaching labs or new research faculty. Funding for these instruments came from a combination of external grants, departmental budget, and new faculty startup funds.