visiting the doctor
DESCRIPTION
猩 红 热 Scarlet fever. 北京大学第三医院 崔蕴璞. Visiting the Doctor. Your subtitle goes here. Contents. 1. Etiology. 2. Epidemiology. 3. Clinical Manifestations. 3. Clinical Manifestations. 4 . Differential Diagnosis. Etiology. Group A hemolytic streptococcal pyogenes. GAS. - PowerPoint PPT PresentationTRANSCRIPT
2. Epidemiology2. Epidemiology
Contents
1. Etiology
4. Differential Diagnosis
3. Clinical Manifestations3. Clinical Manifestations
Extracellular Enzymes and Toxins:
Streptococcal pyogenic exotoxins(SPE) 红疹毒素Streptolysin O and S 溶血素Streptokinase(SK) 链激酶DNAases DNA 酶Hyaluronidase 透明质酸酶Proteinase 蛋白酶
2. Epidemiology2. Epidemiology
Contents
1. Etiology
4. Differential Diagnosis
3. Clinical Manifestations
2. Epidemiology2. Epidemiology
Contents
1. Etiology
4. Differential Diagnosis
3. Clinical Manifestations3. Clinical Manifestations
Prodromal period
Fever
Headache
Abdominal pain
Swollen glands in the neck
Sore throat
White strawberry tongue
Rash period
Rash appears Whithin 24 ~48h after onset of fever
In 12~24h diffused to the whole body
Pastia’s lines
Desquamation
at the end of the 1st week to the 2nd week desquamation occur
comes off as fine flakes like bran
糠屑样脱皮
Characteristic Manifestations
Fever
Typical rash
Strawberry tongue
Pastia’s lines
Circumoral pallor
Desquamation
2. Epidemiology2. Epidemiology
Contents
1. Etiology
4. Differential Diagnosis
3. Clinical Manifestations
Case
A seven year old boy presents with fever for
one day, the temperature rises to 39.5 ℃,
He felt unwell flesh and fell, and complaining
sore throat and headache,
Rash was detected in this morning
Case
PE: T 38.6℃, RR 32/min, HR 110 beats/min.
The mantal status is fine
The throat is red, and the tonsils are enlarged,
reddened, and covered with patches of exudate.
The skin is covered with tiny red spots
No abnormal sign is found in lung, heart and abdomen.
Summary
Scarler fever is an acute infectious disease
caused by group A hemolytic streptococcal pyogenes
Clinical features :Fever, Sore throat, Typical rash,
Pastia’s lines, Circumoral pallor, Desquamation
STSS: invasive GAS, shock and multiple organ
dysfunction