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VIVEKANANDHA

COLLEGE OF ENGINEERING FOR WOMEN

(An Autonomous Institution Affiliated to Anna University-Chennai

Approved by AICTE – Accredited by NBA Ne w Delhi and ISO 9001:2008 Certified)

Elayampalayam, Tiruchengode – 637 205, Namakkal District, Tamilnadu.

DEPARTMENT OF BIOTECHNOLOGY

CURRICULUM & SYLLABI

FOR

UNDER GRADUATE (UG)

REGULATION 2015

( CBCS )

VIVEKANANDHA




Elayampalayam , Tiruchengode – 637 205, Namakkal District, Tamilnadu.

CONTENTS

S.NO. DETAILS PAGE.NO.

1. Curriculum for B.Tech.,BT 1 - 10

2. Syllabi for B.Tech.,BT 11 - 60

VIVEKANANDHA





CURRICULUM

FOR

B.TECH BIOTECHNOLOGY

1

VIVEKANANDHA COLLEGE OF ENGINEERING FOR WOMEN (Autonomous Institution, Affiliated to Anna University, Chennai)

Elayampalayam, Tiruchengode – 637 205

Programme B.E. / B.Tech. Programme Code ---- Regulation 2015

Department ---- Semester I

CURRICULUM (Applicable to the students admitted from the academic year 2015 - 2016onwards)

Course Code Course Name Category Periods / Week Credit Maximum Marks

L T P C CA ESE Total

THEORY

U15EN101 English for Communication – I

*

HS 3 0 2 4 50 50 100

U15MA101 Calculus* BS 4 0 0 4 50 50 100

U15PH101 Physics- I*

BS 3 0 0 3 50 50 100

U15CH101 Chemistry*

BS 3 0 0 3 50 50 100

U15CS101 Fundamentals of Computing and C Programming

*

ES 3 0 0 3 50 50 100

U15GE101 Engineering Graphics*

ES 2 0 4 4 50 50 100

PRACTICAL

Physics and Chemistry Laboratory*

BS 0 0 4 - - - -

U15CS102 Computer Programming in C Laboratory*

ES 0 0 4 2 50 50 100

U15GE102 Engineering Practices Laboratory*

ES 0 0 4 2 50 50 100

Total Credits 25 400 400 800

CA - Continuous Assessment, ESE - End Semester Examination, BS - Basic Sciences, ES - Engineering Sciences, HS - Humanities and Social Sciences * Common Syllabus for CSE, EEE, ECE, IT & BT

- Laboratory classes on alternate weeks for physics and Chemistry .The Laboratory Examination will be held only in the second semester.

2



Programme B.E. / B.Tech. Programme Code --- Regulation 2015

Department --- Semester II

CURRICULUM (Applicable to the students admitted from the academic year 2015 – 2016 onwards)

Course Code Course Name Category Periods / Week Credit Maximum Marks


THEORY

U15EN202 English for Communication- II

*

HS 3 0 2 4 50 50 100

U15MA202 Linear Algebra ,Vector Calculus,and Laplace Transforms

*

BS 4 0 0 4 50 50 100

U15PH202 Physics – II* BS 3 0 0 3 50 50 100

U15GE203 Basic Civil and Mechanical Engineering

*

ES 3 0 0 3 50 50 100

U15CH203 Bio Chemistry# BS 3 0 0 3 50 50 100

U15GE204 Biochemical Thermodynamics

#

ES 3 0 0 3 50 50 100

PRACTICAL

U15PC101 Physics and Chemistry Laboratory

*

BS 0 0 4 2 50 50 100

U15CH204 Biochemistry Laboratory # ES 0 0 4 2 50 50 100

Total Credit 24 400 400 800

CA - Continuous Assessment, ESE - End Semester Examination,BS - Basic Sciences, ES - Engineering

Sciences, HS - Humanities and Social Sciences * Common Syllabus for CSE, EEE, ECE, IT& BT

+ Syllabus for CSE, EEE, ECE, IT

# Syllabus only for BT

3

VIVEKANANDHA COLLEGE OF ENGINEERING FOR WOMEN (Autonomous Institution Affiliated to Anna University, Chennai)


Programme B. Tech Programme

Code 105 Regulation 2015

Department BIOTECHNOLOGY Semester III

CURRICULUM (Applicable to the students admitted from the academic year 2015 - 2016 onwards)

Course Code Course Name

Periods /

Week Credit Maximum Marks


THEORY

U15MA304 Complex Analysis and Partial

Differential Equations#

BS 4 0 0 4 50 50 100

U15BT301 Bioprocess Calculation PC 3 0 2 4 50 50 100

U15GE305 Fluid Mechanics and Momentum

Transfer ES 3 0 0 3 50 50 100

U15BT302 Genetics and Molecular Biology PC 3 0 0 3 50 50 100

U15BT303 Microbiology PC 3 0 0 3 50 50 100

PRACTICAL

U15BT304 Microbiology Laboratory PC 0 0 4 2 50 50 100

U15BT305 Molecular Biology Laboratory PC 0 0 4 2 50 50 100

U15GE306 Fluid Mechanics and Momentum

Transfer Laboratory ES 0 0 4 2 50 50 100


CA - Continuous Assessment, ESE - End Semester Examination

# Common syllabus for ECE, EEE & BT

4



Programme B. Tech Programme Code 105 Regulation 2015

Department BIOTECHNOLOGY Semester IV


Course Code Course Name Periods / Week Credit Maximum Marks


THEORY

U15MA405 Probability and Statistics BS 4 0 0 4 50 50 100

U15BT406 Bioprocess Engineering PC 3 0 0 3 50 50 100

U15BT407 Bio-Heat and Mass Transfer PC 3 0 0 3 50 50 100

U15ITE36 Bioinformatics ES 3 0 0 3 50 50 100

U15BT408 Protein Engineering PC 3 2 0 4 50 50 100

PRACTICAL

U15BT409 Bioprocess Engineering Laboratory PC 0 0 4 2 50 50 100

U15ITE37 Bioinformatics Laboratory ES 0 0 4 2 50 50 100

U15BT410 Bio-Heat and Mass Transfer Laboratory PC 0 0 4 2 50 50 100



5



Programme B. Tech Programme

Code 105 Regulation 2015

Department BIOTECHNOLOGY Semester V




THEORY

U15BA501 Principles of Management HS 3 0 0 3 50 50 100

U15BT511 Advanced Bioprocess

Technology PC 3 2 0 4 50 50 100

U15BT512 Genetic Engineering PC 3 0 0 3 50 50 100

U15BT513 Food Processing Technology PC 3 0 0 3 50 50 100

U15BT514 Plant Biotechnology PC 3 0 0 3 50 50 100

Professional Elective - I PE 3 0 0 3 50 50 100

PRACTICAL

U15BT515 Genetic Engineering

Laboratory PC 0 0 4 2 50 50 100

U15BT516 Food Processing Technology

Laboratory PC 0 0 4 2 50 50 100

U15BT517 Technical Report Writing EEC 0 0 2 1 50 50 100



6

VIVEKANANDHA COLLEGE OF ENGINEERING FOR WOMEN

(Autonomous Institution Affiliated to Anna University, Chennai)



Department BIOTECHNOLOGY Semester VI



Periods /



THEORY

U15BT618 Immunology and

Immunotechnology PC 3 2 0 4 50 50 100

U15BT619 Instrumentation & Process

Control PC 3 0 0 3 50 50 100

U15BT620 Animal Biotechnology PC 3 0 0 3 50 50 100

U15BT621 Bioreaction engineering & Plant design

PC 3 2 0 4 50 50 100

Professional Elective - II PE 3 0 0 3 50 50 100

Professional Elective - III PE 3 0 0 3 50 50 100

PRACTICAL

U15EN603 Communication skills laboratory EEC 0 0 2 1 50 50 100

U15BT622 Immunology and

Immunotechnology Laboratory PC 0 0 4 2 50 50 100

U15BT623 Plant & Animal Biotechnology

Laboratory PC 0 0 4 2 50 50 100



7

VIVEKANANDHA COLLEGE OF ENGINEERING FOR WOMEN (Autonomous Institution Affiliated to Anna University, Chenna i)



Department BIOTECHNOLOGY Semester VII




THEORY

U15BT724 Proteomics & Genomics PC 3 0 0 3 50 50 100

U15BT725 Biopharmaceutical Technology & Drug Development

PC 3 0 0 3 50 50 100

U15BT726 Downstream Processing PC 3 0 2 4 50 50 100

Professional Elective –IV PE 3 0 0 3 50 50 100

Professional Elective –V PE 3 0 0 3 50 50 100

Open Elective - I OE 3 0 0 3 50 50 100

PRACTICAL

U15BT727 Downstream Processing Laboratory PC 0 0 4 2 50 50 100

U15BT728 Internship training EEC 0 0 8 4 50 50 100



8


(Autonomous Institution Affiliated to Anna University, Chennai)



Department BIOTECHNOLOGY Semester VIII




THEORY

Professional Elective - VI PE 3 0 0 3 50 50 100

Open Elective - II OE

3 0 0 3 50 50 100

PRACTICAL

U15BT829 Project EEC 0 0 20 10 50 50 100



Cumulative Course Credit: 185

9




Department BIOTECHNOLOGY Semester -


LIST OF PROFESSIONAL ELECTIVES



PROFESSIONAL ELECTIVE - I

U15BTE01 Professional Ethics 3 0 0 3 50 50 100

U15BTE02 Bioenergetics & Metabolism 3 0 0 3 50 50 100

U15BTE03 Cytogenetics 3 0 0 3 50 50 100

U15BTE04 Advanced Biochemistry 3 0 0 3 50 50 100

PROFESSIONAL ELECTIVE –II

U15BTE05 Enzyme Engineering and Technology 3 0 0 3 50 50 100

U15BTE06 Cancer Biology 3 0 0 3 50 50 100

U15BTE07 Biological waste treatment 3 0 0 3 50 50 100

U15BTE08 Food Biochemistry and Nutrition 3 0 0 3 50 50 100

PROFESSIONAL ELECTIVE –III

U15BTE09 Fermentation Technology 3 0 0 3 50 50 100

U15BTE10 Molecular Biophysics 3 0 0 3 50 50 100

U15BTE11 Analytical Techniques in Biochemistry 3 0 0 3 50 50 100

U15BTE12 System Biology 3 0 0 3 50 50 100

PROFESSIONAL ELECTIVE – IV

U15BTE13 Stem Cell Technology 3 0 0 3 50 50 100

U15BTE14 Developmental Biology 3 0 0 3 50 50 100

U15BTE15 Perl Programming and Bioperl 3 0 0 3 50 50 100

U15BTE16 Principles of Biomedical Engineering 3 0 0 3 50 50 100

10

PROFESSIONAL ELECTIVE –V

U15BTE17 Biopharmaceutical Technology and Drug

Development 3 0 0 3 50 50 100

U15BTE18 Therapeutic Nutrition 3 0 0 3 50 50 100

U15BTE19 Entrepreneurship 3 0 0 3 50 50 100

U15BTE20 Bio-Business 3 0 0 3 50 50 100

PROFESSIONAL ELECTIVE –VI

U15BTE21 Biosensor & Biotransducers 3 0 0 3 50 50 100

U15BTE22 Nanobiotechnology 3 0 0 3 50 50 100

U15BTE23 Clinical Trial & Management 3 0 0 3 50 50 100

U15BTE24 Bioethics,Biosafety & IPR 3 0 0 3 50 50 100

U15BTE25 Total Quality Management 3 0 0 3 50 50 100


VIVEKANANDHA





SYLLABI

FOR

B.TECH BIOTECHNOLOGY

11



Programme B.E. / B.Tech. Programme Code ---- Regulation 2015

Department CSE, EEE, ECE, IT & Bio-Tech. Semester I


Periods Per Week

Credit Maximum Marks


U15EN101 English for Communication – I 3 0 2 4 50 50 100

Course

Objective

The Main Objective of this course is to

Give students knowledge about the correct usage of English with an emphasis on reading skills in order to be able to study effectively and think logically.

Practice writing skills at the sentence and paragraph levels with correct grammatical structures.

Practice listening and speaking skills so as to be able to communicate their thoughts in professional & corporate context effectively.

Enable students to acquire comprehensive English skills to express their technical and non-technical ideas through the LSRW skills efficiently

Abbreviation L –Listening , R –Reading, W –Writing , S –Speaking, LF- Language Focus

Unit - I Periods 12

L-Types of Listening R - Basic Reading Comprehension W- Introduction to writing strategies S- Conversational Skills LF - Language Focus-Technical terms, collocations and Grammar SUGGESTED ACTIVITIES :L-Listening to conversations, R-Reading Instructions and Technical Manuals, W- Writing Definitions, S-Short Conversations through role play, LF - Activities relating to understanding and using active and passive general and technical vocabulary Basic sentence patterns; Exercises relating to technical terms, tenses (past, present, perfect and continuous tenses).

Unit - II Periods 12

L- Types of Listening R - Reading Comprehension W- Introduction to writing strategies S - Strategies for developing conversational skills LF-Tenses and concord SUGGESTED ACTIVITIES:L-Listening to lectures, listening to description of equipment, R-Reading e-mails, Reading headlines, predicting content, W-Note making, writing descriptions, S-Asking questions, participating in discussions, LF-Exercises related to special uses of tenses, Subject - verb agreement

Unit - III Periods 12 L- Enhancing Listening Skills R - Intensive reading W- Effective writing strategies S -Improving fluency through oral practice LF- Form and Informal usage of words, Use of the passive forms SUGGESTED ACTIVITIES: L-Listening to different kinds of interviews (Face - to - face, radio, TV and telephone interviews), R-Reading passages for gist, W-Informal writing -short e-mails (Focus on brevity, coherence and cohesion), Memos, S-Role play and describing, LF-Descriptive words, verbs to describe processes, informal language used in conversation, guessing meanings of unknown vocabulary, exercises related to the passive voice (conversion from active to passive, impersonal passive forms).

Unit - IV Periods 12

L - Note taking R - Reading strategies W- Effective writing strategies – Informal S - Improving fluency through oral practice LF - Cause and Effect, Modals SUGGESTED ACTIVITIES L-Taking down notes, R-Reading passages for specific information,W- Phone messages (Focus on brevity, coherence and cohesion), S-Pronunciation (Phonetic sounds - vowels, consonants and diphthongs),LF-Exercises related to cause and effect (if - clauses and types), usage of modal verbs.

Unit - V Periods 12 L - Listening for nuances of tone R - Reading for a purpose, information transfer W- Effective writing strategies –

12

Formal S - Improving fluency through oral practice LF - Descriptive Vocabulary - Word building . SUGGESTED ACTIVITIES: L-Activities relating to variation in tone, listening to welcome speeches, R-Reading business documents, interpreting graphical representations, W-Writing business e-mails, S-Segmental and suprasegmental features-stress and intonation, LF -Exercises related to describing objects and usage of prefixes and suffixes, synonyms and antonyms.

Total Periods 60

REFERENCES:

1. Dr.Padma Ravindran,Poorvadevi,M.Y.Abdur Razack-English for life, English for work, students Book,Ebek language laboratory pvt ltd,2011

FURTHER READINGS:

1. Dutt Rajeevan, Prakash. A Course in Communication Skills(Anna University, coimbatore edition) : Cambridge University Press India Pvt.Ltd, 2007

2. Meenakshi Raman and Sangeeta Sharma-'Technical Communication English Skills for Engineers'; Oxford University Press, 2008.

3. S.P. Dhanavel, English and Communication Skills for Students of Science and Engineering, Orient Blackswan Pvt, Ltd, 2009.

4. Technical English – I & II, Sonaversity, Sona College of Technology, Salem, First Edition, 2012.

Course Outcome: The students will be able to

Develop an ability to interpret, evaluate, and apply what they read to their college courses and real- life situations.

Expand & Develop complete, concise, concrete, correct, clear, and courteous professional letters and memoranda. Produce disciplined pieces of personal exposition, description, and narration, as

well as several expressions according to professional embodiment. Appreciate that keeping current with professional standards and practices is expected for optimum effectiveness in the professional and academic domain.

Participate in classroom discussions with emphasis on narrating and describing situations to develop oral communication skills including fluency, idea sequencing, accuracy, vocabulary and

pronunciation. Participate and be sufficiently understood in role-playing, simulating effective proficient quality.

Paraphrase the ideas of classroom lessons and turn them into coherent and well developed notes.

EXTENSIVE READING:

1. Paulo Coelho, The Alchemist, Published May 1st 1993 by HarperCollins.

2. Stephen R.Covey, The 7 Habits of Highly Effective People: Powerful Change, Paperback, Anniversary Edition, 372 pages, Published November 9, 2004.

3. Mary Pope Osborne, Run , Run, as Fast as You Can! 198 pages, Published Jan- 1, 2001 Lutterworth Press.

E RESOURCES FOR EXTENSIVE READING:

http://www.sparknotes.com/lit/the-alchemist/summary.html http://www.cliffsnotes.com/literature/a/the-alchemist/book-summary https://www.stephencovey.com/7habits/7habits.php http://en.wikipedia.org/wiki/The_Seven_Habits_of_Highly_Effective_People http://en.wikipedia.org/wiki/Mary_Pope_Osborne

http://www.sparknotes.com/lit/the-alchemist/summary.html

http://en.wikipedia.org/wiki/The_Seven_Habits_of_Highly_Effective_People

http://en.wikipedia.org/wiki/Mary_Pope_Osborne

13



Programme B.E. / B.Tech. Programme Code Regulation 2015 Department CSE, EEE, ECE, IT & BIO-TECH. Semester I

Course Code Course Name Periods Per



U15MA101 Calculus 4 0 0 4 50 50 100

Course Objective

The Main Objective of the course is to

Provide the information about Review of limits, continuity and

differentiability.

Understand maxima and minima and Lagrangian Multiplier

Demonstrate Integral calculus. Identify the problems based on area, surface, volume.

Recognize Second order linear differential equations.

Unit – I DIFFERENTIAL CALCULUS

Periods 12

Limit, continuity, differentiability, rules of differentiation, differentiation of various functions, Rolle‟s theorem, Mean value theorem, Intermediate value theorem, Taylor‟s theorem, Maxima and Minima.

Unit – II FUNCTION OF SEVERAL VARIABLES Periods 12 Partial derivatives – Total derivatives – Taylors‟s theorem – maxima and minima, Lagrangian multipliers, Jacobians

Unit – III INTEGRAL CALCULUS Periods 12 Riemann integral- Fundamental theorem of calculus - methods of integration (Integration by parts, Trigonometric integrals, Trigonometric substitutions, Integration of rational functions by partial fraction,

Integration of irrational functions) -Reduction formula on 2

0

cos

xdxn,

2

0

sin

xdxnand

2

0

sincos

xdxx nm

Unit – IV MUTIPLE INTEGRALS Periods 12 Double and Triple integration- Change of order of integration - Applications to area, surface and volume - Change of variables

Unit – V ORDINARY DIFFERENTIAL EQUATIONS Periods 12 Second order Linear ordinary differential equations with constant coefficients, Cauchy‟s - Euler equations- Legendre‟s Linear differential equations - Method of variation of parameters.

Total Periods 60

TEXT BOOKS:

1. James Stewart, Calculus (7th

Edition), Cengage Learning , 2012.

2. G. B. Thomas and R. L. Finney, Calculus and Analytic Geometry (9

th Edition), ISE

Reprint, Addison-Wesley, 1998

REFERENCES:

1. E. Kreyszig, Advanced engineering mathematics (10

th Edition), John Wiley (2015),(Unit

III,IV.V).

2. W. E. Boyce and R. DiPrima, Elementary Differential Equations (8

th Edition), John Wiley

( 2005).

14

Course

Outcome

The students will be able to

Apply Mean value theorem and Taylors theorem.

Analyze Jacobian and Lagrangian multipliers.

Formulate Reduction Formulae.

Translate Change of order of integration Apply method of variation of parameters.

15


(Autonomous Institution, Affiliated to Anna University ,Chennai)


Programme B.E/B.Tech Programme code Regulation 2015

Department CSE, ECE, EEE, IT & Bio-Tech. Semester I

Course code Course name

Periods per

week Credit Maximum Marks


U15PH101 PHYSICS-I

3 0 0 3 50 50 100

Course

Objective

The main objective of this course is to: Familiarize interference, principles of Fiber optics & its applications

Impart basic concepts of diffraction, polarisation

Understand theorems in dynamics of fluid

Gain knowledge of thermal physics

Identify different crystal structures, lattices

Unit - I Interference Periods 9

Superposition principle, intensity distribution, condition for interference, coherent and non coherent source,

classification of fringes. Engineering application of interference phenomena, Michelson Interferometer, Air wedge,

Anti reflection coating, Fiber optics – Principle and Propagation of light in optical fibers – Numerical Aperture and

Acceptance angle-applications of fiber optics – Displacement sensor, Temperature sensor.

Unit - II Diffraction & Polarisation Periods 9

Fraunhoffer diffraction for single slit and double slit, diffraction grating, resolving power of a grating, image

forming systems.

Propagation of electromagnetic wave and its representation, concept of phase, random, plane, circular and elliptical

polarised light. Polarisation of light by reflection, polariser (Malus law).

Unit - III Dynamics of Fluid Periods 9

Continuity equation, Bernoulli‟s theorem and its application- Torcelli‟s theorem, Viscosity flow of liquid through

a capillary tube, Comparison of Viscosity - Ostwald‟s Viscometer, Poiseuille‟s equation, Stoke‟s formula, effect of

temperature and pressure on viscosity.

Unit - IV Thermal Physics Periods 9

Kinetic theory of gases. Maxwellian dist., imperfect gases, Van der waal‟s equation of states, Radiation,

Conduction, Convection, production and measurement of low and high pressure, Thermal conductivity of bad

conductor-Lee‟s disc and its derivation,– IR Camera.

Unit - V Crystal Physics Periods 9

Lattice – Bravais space lattice – Lattice planes –Miller indices- d spacing in cubic lattice – Unit cell - Calculation of

number of atoms per unit cell- Atomic radius – Coordination number- Packing Factor for SC, BCC, FCC and HCP

structures – Crystal defects –point, line and surface defects – Burger vector.

Total Periods 45

References:

16

1. B.K. Pandey, S. Chaturvedi. “Engineering Physics”, 1

st Edition, Cengage Learning

India Pvt Ltd, (2012).

2. A.Ghatak(AG), Optics, 3rd

Edition, Tata Mcgraw Hill, 2005 3. Fundamentals Of Physics Extended 8/Ed 8th Edition, David Halliday, Robert Resnick Jearl Walker, Wiley India Pvt Ltd, 2008.

4. V.Rajendran,”Engineering Physics” McGraw Hill Education Pvt Ltd,2013.

Course Outcome

The student will be able to

Differentiate between interference and diffraction phenomena

Apply concepts of dynamics of fluid in related fields

Derive equation for thermal conductivity

Determine packing factor for various unit cells

http://www.flipkart.com/author/david-halliday

http://www.flipkart.com/author/robert-resnick

http://www.flipkart.com/author/jearl-walker

17


(Autonomous Institution Affiliated to Anna University Chennai)


Programme B.E/B.Tech. Programme code Regulation 2015

Department CSE, ECE, EEE, IT & Bio-Tech. Semester I

Course code Course name Periods per week Credit Maximum Marks


U15CH101 CHEMISTRY

3 0 0 3 50 50 100

Course

Objective

The main objective of this course is to:

Familiarize different types of electrodes, and its equations.

Acquire Knowledge about Nanomaterial‟s and its applications.

Recognize the concepts of Thermodynamics and their engineering applications.

Cram knowledge about different types of batteries, metals and its corrosion resistance.

Unit - I BATTERIES AND FUEL CELLS Periods 9

Electro chemistry-Basics-Types of electrodes-Standard Hydrogen electrode-Calomel electrode - Batteries and fuel cells - basic concepts - characteristics - classical batteries (Pb-Acid) - modern batteries (Ni-Metal Hydride) - Lithium batteries (LiTiS2)- Hydrogen-Oxygen fuel cells - merits of fuel cells and applications of batteries - Solar cell - functions and applications.

Unit - II NANO MATERIALS Periods 9

Introduction – Basics - distinction between molecules, nanoparticles and bulk materials; size-dependent properties.

Structures of Nanomaterials-Nanoparticles - Synthesis: Precipitation, sol gel method, laser ablation, spray pyrolysis,

Chemical vapour deposition, Arc-discharge method; properties and applications

Unit - III POLYMERS AND CONDUCTING POLYMERS Periods 9

Definitions - classification of Polymers - types of polymerization - Mechanism of polymerization - Plastics – Introduction-

Types - thermo set - thermo plastics – prepration,prperties and applications of (PE,PMMA,PC, Bakelite, Urea

formaldehyde) ) - Conducting polymers - conduction mechanism of poly acetylene, polypyrrole and polyaniline.

Unit - IV THERMODYNAMICS Periods 9

The Laws of thermodynamics - Enthalpy – Entropy – free energy change –Helmholtz and Gibbs free energy functions -

Criteria for the spontaneity of the reaction-reversible and irreversible reaction Claussius - Clapeyron equation – Maxwell‟s

relations – Van‟t Hoff isotherm and isochore – problems

Unit - V CORROSION AND ITS CONTROL Periods 9

Corrosion-Types-ChemicalCorrosion -ElectrochemicalCorrosion(galvanic and Differential aeration)-Factors influencing

corrosion – Material selection and design aspects-control methods of corrosion –Sacrificial anodic and impressed current

cathodic protection-Protective coatings- Pilling Bedworth rule- electro plating (Au on Cu) - electro less plating (Ni).

Total Periods 45

Course

Outcome

The students will be able to:

Understand different types of electrodes and their applications.

Predict the information of Nanoparticles and their industrial applications

Apply Thermodynamics properties for engineering applications.

Construct batteries and identification of metal‟s resistance towards corrosion. Text Books:

1. Dr. S. Vairam and Dr. Subaramesh, Engineering Chemistry: First Edition, Wiley publication,2014

2. O.G.Palanna,”Engineering Chemistry”Tata Mc GrawHill PVT,Ltd. Edition -4-2012

18

3. J.D. Lee, Inorganic Chemistry, Edition- 8- Wiley India private ltd.-2011.

4. Physical Chemistry: P.W. Atkins, Puri, Sharma and Pathnia,Vishal Publishers,.Edition- 5- 2010.

References

1. Engineering Chemistry: Jain & Jain, Edition- 13- 2013.

2. Engineering Chemistry: Sashi Chawla, Edition- 5- 2010.

3. NPTEL –Course notes (for further reference)

19



Programme B.E. / B.Tech. Programme Code Regulation 2015

Department CSE, EEE, ECE, IT & Bio-Tech. Semester I


Periods Per



U15CS101

Fundamentals of

Computing and C

Programming

3 0 0 3 50 50 100

Course

Objective

The Main objective of this course is

Know about the components of Computer

Understand the basics of problem solving methods.

learn the fundamentals of C programming

learn how to write C programs for solving real time problems

Unit - I COMPUTER FUNDAMENTALS Periods 9

Introduction – Evolution – Generation – Classification – Components of Computer Systems – Application – Evolution of Internet – Classification of Programming Languages – Algorithm , Pseudo Code , Flowchart.

Unit - II FUNDAMENTALS OF C Periods 9 Introduction – Identifier, Keywords, Variables, Data types of C, Constants – Operators and Expression – Type conversion in C – Formatted Input and Output functions – Decision Making and Branching – Conditional Operators – Switch Statement, While Construct, GOTO statements, Nested Loops.

Unit - III ARRAYS AND STRINGS Periods 9 Introduction – One Dimensional Arrays – Working with 1D Array – Strings – String Manipulations – N Dimensional Array – Working with 2D Arrays – Arrays of Strings – Manipulating String Arrays.

Unit - IV FUNCTIONS AND POINTERS Periods 9

Concept of Function – User Defined Functions – Scope Rules – Storage Classes – Recursion, Common Errors – Pointers: Void and Null Pointers – Arrays and Pointers – Pointer and Strings, Pointer Arithmetic – Dynamic Memory Allocation.

Unit - V USER DEFINED DATA TYPES & VARIABLES Periods 9

Introduction – Structures – Structures within Structures – Array of Structures – Array within Structures – Structures and Pointers – Structures and Functions – Union – Enumeration Types – Bit Fields.

Total Periods 45

SUGGESTED TEXTS AND REFERENCE MATERIALS:

1. Pradip Dey and Manas Ghosh, “Fundamentals of Computers with Programming in C”, First Edition, Oxford University Press, 2009.

2. Behrouz A.Forouzan and Richard.F.Gilberg,”A Structured Programming Approach Using C”, II edition,Brooks-Cole Thomson Learning Publications,2007.

3. Balagurusamy. E “Programming in ANSI C”, Fourth Edition, Tata McGraw Hill, 2008.

4. Ashok N. Kamthane, “Computer Programming”, Second Edition, Dorling Kindersley (India) Pvt. Ltd., Pearson Education, 2012.

5. Anita Goel and Ajay Mittal, “Computer Fundamentals and Programming in C”, Dorling Kindersley

20

(India) Pvt. Ltd., Pearson Education in South Asia, 2011.

6. Byron Gottfried, “Programming with C”, 2

nd Edition, (Indian Adapted Edition), TMH publications,

2006.

7. Stephen G.Kochan, “Programming in C”, Third Edition, Pearson Education India, 2005.

Course Outcome

The Students will be able to

Write C program for simple applications

Formulate algorithm for simple problems

Analyze different data types and arrays Use C programming language to solve problems

21

VIVEKANANDHA COLLEGE OF ENGINEERING FOR WOMEN (AUTO NOMOUS INSTITUTIO N AFFILIATED TO ANNA UNIVERSITY, CHENNAI)


Programme B.E / B.Tech Programme

Code Regulation 2015

Department CSE, EEE, ECE, IT and Bio Tech. Semester I



U15GE101 Engineering Graphics 3 2 0 4 50 50 100

Course

Objective

The Main objective of this course is to 1. Identify the importance of Engineering Graphics and know its relevance in Engineering

Applications. 2. Know Orthographic Projection and to describe & recognize its importance. 3. Explain the position of objects with respect to the plane of projection. 4. Understand the invisible details of the object and to develop the surfaces of the objects. 5. Explain the importance of isometric projection and pictorial projection of objects.

Concepts and Conventions

(Not for Examination)

Importance of graphics in engineering applications – Use of drafting instruments – BIS conventions and specifications – Size, layout and folding of drawing sheets – Lettering and dimensioning.

Periods 1

Unit - I Plane curves, Projection of points, lines and plane surfaces Periods 5+9

Introduction to P lane curves, Orthographic projection – principles – projection of points, straight lines (only first

angle projections) and plane surfaces (polygonal and circular).

Unit - II Projection of solids Periods 5+9

Projection of simple solids like prisms, pyramids, cylinders and cones when the axis is inclined to one of the

principal planes by change of position method.

Unit - III Section of solids Periods 5+9

Sectioning of above solids in simple vertical position when the cutting plane is inclined to the one of the principal

planes and perpendicular to the other – obtaining true shape of section.

Unit - IV Development of surfaces Periods 5+9

Development of lateral surfaces of simple and truncated solids – prisms, pyramids, cylinders and cones.

Unit - V Isometric projections, Orthographic views from pictorial views and

Perspective projections Periods 6+12

Isometric projections, orthographic views from pictorial views and Introduction to Perspective projections – Visual

ray method.

COMPUTER AIDED DRAFTING (Demonstration only) Introduction to drafting packages and demonstration of their use.

22

Total Periods 75

Suggested texts and reference materials

Text book:

1. Bhatt.N.D and Panchal V.M., “Engineering Drawing”, Charotar Publishing House .

References:

1. Venugopal K, Prabhu Raja V, “Engineering Graphics “New Age International Publishers.

2. Natarajan K V, "Engineering Drawing and Graphics", M/s. Dhanalakshmi. N, Chennai

3. Bureau of Indian Standards, “Engineering Drawing Practices for Schools and Colleges SP 46- 2003”, BIS

New Delhi.

Course Outcome The students will be able to 1. Communicate the details of the objects through graphical language. 2. Understand the importance of the three views of a geometrical object like points, line, planes, and solids. 3. Prepare three views of geometrical objects in their given position with reference to the planes of projection. 4. Explain the invisible details and development of the surfaces of an object. 5. Convert the pictorial projection into orthographic projection and orthographic projection into Isometric

projection.

23


(Autonomous Institution, Affiliated to Anna University Chennai)


Programme B.E/B.TECH Programme code Regulation 2015

Department CSE, EEE, ECE, IT and Bio Tech. Semester I

Course

code Course name

Periods per week Credit Maximum Marks


PHYSICS AND CHEMISTRY

LABORATORY 0 0 4 0 50 50 100

Course

Objective


Identify prominent wavelengths using mercury lamp

Gain knowledge in measuring the lowest thickness materials

Understand elastic behavior of Materials

Observe heat conduction in bad conductor

Predict viscous force in liquids.

SUGGESTED LIST OF EXPERIMENTS Periods 2

PHYSICS 1. a) Determination of Laser Wavelength. b) Particle size determination using Diode Laser 2. Determination of wavelengths of mercury spectrum – spectrometer grating. 3. Determination of thickness of the thin wire – Air wedge method. 4. Determination of Numerical Aperture, Attenuation and Acceptance angle using Optical Fiber. 5. Determination of Young‟s modulus of the material - Non uniform bending method. 6. Determination of thermal conductivity of a bad conductor using Lee‟s Disc Method. 7. Determination of viscosity of liquid – Poiseuille‟s method.

Total Periods 30

Course Outcome : The students will be able to :

Observe and measure different wavelengths of mercury spectrum.

Calculate thickness of thin wire using Air wedge.

Infer about elastic properties of materials based on young‟s modulus.

Illustrate the conductivity of bad conductors.

Use poiseuille‟s method to find viscosity of the liquids.

Course

Objective


Gather basic simple acid and base reactions.

Collect the mechanism of acid mixture with base.

Enumarate the reactions involved in the formation of a precipitate.

Study the pH and potential for identifying of acid, base, ferrous solution.

Learn the structure and the percentage of water present in copper sulphate.

Quote iron forms complex with thiocyanate.

24


CHEMISTRY

1. Conductometric titration (Simple Acids and Bases).

2. Conductometric titration (Mixture of weak and Strong Acids).

3. Conductometric titration (Precipitation Titration).

4. Potentiometric titration (Fe2+

/KMnO4 or K2Cr2O7).

5. pH metric titration (Acids and Bases).

6. Determination of water of crystallization of a crystalline salt (Copper sulphate)

7. Estimation of Ferric ion by Spectrophotometry.

Total Periods 30

Course Outcome : The students will be able to :

Infer knowledge on neutralization reaction between acid and base.

Identify acid mixtures estimation with base through reaction.

Evaluate the reaction of BaCl2 & Na2SO4 with the formation of a precipitate.

Classify the pH and potential for estimation of acid, base, ferrous solution.

Find out the percentage of water and reason for the colour of copper sulphate.

Calculate the formation of complex for estimation of iron.

25



Programme B.E. / B.Tech. Programme Code Regulation 2015 Department CSE, EEE, ECE, IT & Bio-Tech. Semester I

Course Code Course Name Periods Per Week Credit Maximum Marks


U15CS102 Computer Programming in C

Laboratory 0 0 4 2 50 50 100

Course

Objective


Understand the basic programming constructs and articulate how they are used to develop a program with a desired runtime execution flow.

Articulate where computer programs fit in the provision of computer based solutions to real world problems.

learn to use user defined data structures

SUGGESTED LIST OF EXPERIMENTS

1. Work with MS office/ Open Office for search, Generate and Manipulate data.

2. Process with Presentation and Visualization-graphs, charts, 2D, 3D.

3. Problem formulation, Problem Solving, Algorithms and Flowcharts.

4. Implement C Program using Simple statements and expressions.

5. Implement scientific problems solving using decision making and looping.

6. Implement C program for 1D and 2D arrays.

7. Basic C program for solving problems and string functions

8. C program using a user defined functions.

9. C program using Recursive functions.

10. C program for Structures and Unions.

TOTAL: 45 PERIODS

Course Outcome:


Prepare document using MS Word. Prepare charts using MS Excel

Write and compile programs using C.

Demonstrate the use of conditional statement

Write program with the concept of Structured Programming

26

VIVEKANANDHA COLLEGE OF ENGINEERING FOR WOMEN (AUTO NOMOUS INSTITUTIO N AFFILIATED TO ANNA UNIVERSITY, CHENNAI)


Programme B.E / B.Tech Programme Code Regulation 2015

Department CSE, EEE, ECE, IT & Bio Tech. Semester I


Periods per



U15GE102 Engineering Practices Laboratory 0 0 4 2 50 50 100

Course

Objective

The Main objective of this course is to

Know the joints and the way to assemble to prepare the pipe line circuits in plumbing and the

wooden furniture in carpentry,.

Know the importance of machining, welding and how the raw material is prepared to a

desired shape.

Know the concept of development of surface and how to make sheet metal objects.

GROUP A (CIVIL & MECHANICAL ENGINEERING)

I. CIVIL ENGINEERING PRACTICE

1.Plumbing :

(a) Study of pipeline joints, its location and functions: valves, taps, couplings, unions, reducers and

elbows in household fittings.

(b) Hands-on-exercise:

Basic pipe connections – Mixed pipe material connection – Pipe connections with different

joining components.

2.Carpentry:

(a) Study of the joints in roofs, doors, windows and furniture.

(b) Hands-on-exercise:

Wood work, joints by sawing, planning and cutting.

II. MECHANICAL ENGINEERING PRACTICE

1.Welding:

(a) Preparation of arc welding of butt joints, lap joints and tee joints.

(b) Gas welding practice

2.Basic Machining:

(a) Turning and Facing

(b) Drilling Practice

3.Sheet Metal Work:

(a) Forming & Bending:

(b) Model making – Tray and Basket.

4.Demonstration on:

(a) Foundry operations like mould preparation for gear and step cone pulley.

(b) Fitting – Exercises – Preparation of square fitting and vee – fitting models.

27

5. Study of Air Conditioner & Centrifugal Pump.

GROUP B (ELECTRICAL & ELECTRONICS ENGINEERING)

III. ELECTRICAL ENGINEERING PRACTICE

1. Residential house wiring using switches, fuse, indicator, lamp and energy meter.

2. Fluorescent lamp wiring.

3. Stair case wiring

4. Measurement of electrical quantities – voltage, current, power & power factor in RLC circuit.

5. Measurement of energy using single phase energy meter.

6. Measurement of resistance to earth of electrical equipment.

7. Demonstration on Soldering & Brazing

8. Hands on exercises/assembly of Computer, Laptop, Cell phone, Fan , Iron box etc.

IV. ELECTRONICS ENGINEERING PRACTICE

1. Study of Electronic components and equipments – Resistor, colour coding measurement of AC signal

parameter (peak-peak, rms period, frequency) using CR.

2. Study of logic gates AND, OR, EOR and NOT.

3. Generation of Clock Signal.

4. Soldering pr a c t ic e – Components Devices and Circuits – Using ge ne r a l purpose PCB.

5. Measurement of ripple factor of HWR and FWR.

TOTAL PERIODS:60

Course outcome


1. Prepare the pipe line circuits and the joints to make furniture.

2. Prepare desired shape and make permanent joints.

3. Prepare the sheet metal objects in an efficient manner.

28



Programme B.E. / B.Tech. Programme Code Regulation 2015 Department CSE, EEE, ECE, IT & Bio-Tech. Semester II



U15EN202 English for Communication - II 3 0 2 4 50 50 100

Course

Objective

The Main objective of the course is to

Demonstrate good listening skills for academic and professional purposes

Exhibit effective reading skills.

Improve their vocabulary. Write effectively in informal and professional situations.

Abbreviation L –Listening , R –Reading, W –Writing , S –Speaking, LF- Language Focus

Unit - I Periods 12 L - Listening to cultural awareness R - Inferential Reading W- Letter writing - Informal and Formal S - Developing confidence LF - Adjectives, Degrees of comparison. SUGGESTED ACTIVITIES: L-Listening to casual conversations, talks, interviews and lectures R-Reading short messages and technical articles, W-Thank you letters, calling for quotations, placing an order, seeking clarification, letters of complaint, S-Describing and Discussing, LF-Exercises-equal and unequal comparison.

Unit - II Periods 12

L - Listening to specific information relating to technical content R - Reading Texts W- Letter writing – Formal S - Expressing opinions LF - Simple, compound and complex sentences. SUGGESTED ACTIVITIES: L-Listening for statistical information, R-Exercises related to articles (in magazines) and comparing articles, W-Letter seeking permission to undergo practical training and undertake project work, S-Exercises related to discussing, describing role play and oral summarizing, LF-Exercises related to transformation of sentences.

Unit - III Periods 12 L - Listening to specific information relating to technical content R - Skimming and Scanning W- Formal Letter writing S - Giving Instructions LF - Pronouns, Phrasal verbs, Restrictive and Non - restrictive clauses. SUGGESTED ACTIVITIES: L-Exercises related to listening to interviews and presentations, R-Reading Job applications, W-Applying for a Job, Writing a CV, S-Exercises related to discussing, describing role play and oral summarizing of instructions, LF-Exercises related to vocabulary and Grammar.

Unit - IV Periods 12

L - Listening and retrieving Information R-Skimming and Scanning W- Letter writing, Report writing S - Developing fluency and Coherence LF - Countable, Uncountable nouns, Vocabulary relating to graphical representation, Recommendations. SUGGESTED ACTIVITIES: L-Exercises related to listening and retrieving information, R-Reading and understanding advertisements, W-Letters to the Editor, Letter of Complaint, Various kinds of Report writing meetings, industrial visits, S-Activities related to intonation and improving voice quality, LF-Exercises related to vocabulary and grammar structure and examples of situational recommendations (Should form).

Unit - V Periods 12

L - Listening and retrieving Information R - Predicting content W- Writing proposals, Agenda, Minutes of the meeting S - Developing coherence and self-expression, making presentations LF - British and American Vocabulary, Error Detection, Punctuation. SUGGESTED ACTIVITIES: L-Exercises related to listening and retrieving information, gapped texts R-

29

Interpreting reports, W-Writing Proposals (Symposia, seminars, conferences) Agenda and Minutes of the meeting (Class committee meeting etc.), S-Paralinguistic and extra linguistic features (body language, short presentations), LF -Exercises related to British and American vocabulary (Differences in vocabulary, spelling etc), Editing texts.

Total Periods 60

REFERENCES:

1. Norman Whitby - Business Benchmark Pre-Intermediate to Intermediate, Students Book, Cambridge University Press, 2008. , 1997.

FURTHER READINGS:

1. Dutt, Rajeevan, Prakash .A Course in Communication Skills (Anna University, Coimbatore edition) :. Cambridge University Press India Pvt.Ltd, 2007.

2. Meenakshi Raman and Sangeeta Sharma-'Technical Communication English Skills for Engineers'; Oxford University Press, 2008.

3. S.P. Dhanavel, English and Communication Skills for Students of Science and Engineering, Orient Blackswan Pvt, Ltd, 2009.

4. Technical English – I & II, Sonaversity, Sona College of Technology, Salem, First Edition, 2012.

EXTENSIVE READING:

1. Spencer Johnson, Who moved my Cheese? Publishers: RHUK (4 March 1999), Publication date- September 8, 1998.

2. Jim Stovall, The Ultimate Gift, Published- Jan 1, 1999.

3. Arundhati Roy, The God of Small Things (1997) publisher –IndiaInk India, Publication date 1997.

E RESOURCES FOR EXTENSIVE READING:

http://www.kalevleetaru.com/Publish/Book_Review_Who_Moved_My_Cheese.pdf http://www.bookbrowse.com/reviews/index.cfm/book_number/304/who-moved-my-cheese http://www.imdb.com/title/tt0482629/plotsummary http://www.beyondsilverandgold.com/the-ultimate-gift-by-jim-stovall-book-review/ http://www.gymmuenchenstein.ch/stalder/klassen/lm/3lm_rw/04.htm http://www.shmoop.com/god-of-small-things/chapter-1-summary.html

Course

Outcome


Listen to listen for nuances of tone, variation in tone and to listen to welcome speeches.

Read passages for specific information, a purpose and information transfer, business documents and interpreting graphical representations.

Learn informal Writing – short e-mails, writing phone messages, formal Writing and writing business e-mails

Learn Pronunciation (Phonetic Sounds), Vowels, consonants and diphthongs and improving fluency through oral practice

30



Programme B.E. / B.Tech. Programme Code Regulation 2015 Department CSE, EEE, ECE, IT & Bio-Tech. Semester II

Course Code Course Name Periods Per



U15MA202

Linear Algebra, Vector Calculus

and Laplace Transforms.

4 0 0 4 50 50 100

Course Objective


Introduce the rank of the matrix.

Understand Eigen values and Eigen vectors and its role in the system of equations.

Demonstrate Gradient and divergence

Proficiently understand the vector integral calculus

Identify the Laplace transform of derivatives and integrals.

Unit - I VECTOR SPACE Periods 12 Vectors of linear independence and dependence, Review of matrices, rank of a matrix (in terms of row space), systems of linear equations-Gauss elimination.

Unit - II EIGENVALUES AND EIGENVECTOR Periods 12 Eigen values and eigenvectors, Eigen values of special matrices (orthogonal, unitary). Similarity transformation- diagonalization – principal axis(canonical form) - Quadratic forms – Reduction to canonical forms

Unit - III VECTOR DIFFERENTIAL CALCULUS Periods 12

Vector fields - Gradient, divergence and curl – Directional Derivative – Irrotational and Solenoidal vectors - Tangents and Normal‟s.

Unit - IV VECTOR INTEGRAL CALCULUS Periods 12

Line, Surface and Volume integrals , Green‟s theorem in a plane, Gauss Divergence theorem, Stokes theorem (Excluding proof)- simple applications involving rectangular parallelepipeds and spheres.

Unit-V LAPLACE TRANSFORMS 12

Laplace Transform generalities - Transforms of elementary functions-Basic properties-Transform of Derivatives and integrals-Transform of unit step function and impulse functions-Transform of periodic functions. Definition of Inverse Laplace transform –Convolution theorem (excluding proof)-Initial and final value theorems-Solution of ODE of second order with constant coefficients using Laplace transformation techniques

Total Periods 60

TEXT BOOKS:

1. E. Kreyszig, Advanced engineering mathematics (10th Edition), John Wiley (2015). 2. S. Kumaresan, Linear algebra - A Geometric approach, Prentice Hall of India (2000).

REFERENCES: 1. H. Anton, Elementary linear algebra with applications (8th Edition), John Wiley (1995).

2. Ray Wylie C. and Barrett , L.C. Advanced Engineering Mathematics , McGraw-Hill Companies; 6

th Edition (1995)

31

Course

Outcome

The Students will be able to

Analyze the Rank of the matrix.

Derive the Eigen values and Eigen vectors of the matrices.

Demonstrate Vector Differential Calculus.

Apply Greens's Stocke's,Gauss Diverernce theorems

Recognize the Laplace transform of unit step and unit impulse functions.

32


(Autonomous Institution, Affiliated to Anna University ,Chennai)



Department CSE, ECE, EEE, IT & Bio-Tech Semester II


Periods per



U15PH202 PHYSICS-II

3 0 0 3 50 50 100

Course

Objective


Classify properties of semiconducting materials

Compare the Dia, Para, Ferro magnetic materials

Classify the Dielectric materials based on the properties Gain knowledge of thermoelectricity

Understand concepts of modern physics

Understand concepts of modern physics

Unit - I Semiconducting Materials Periods 9

Introduction to semiconductors-Quantum mechanical concepts, Electron in a potential well, density of states, Fermi energy, Bonding in solids, effective mass, electrons and holes, mobility, Hall effect, Carrier concentration- intrinsic and extrinsic semiconductors (Derivation), Law of mass action.

Unit - II Magnetic Materials Periods 9

Origin of magnetic moment – Bohr magneton – comparison of Dia, Para and Ferro magnetism – Domain theory – Hysteresis – soft and hard magnetic materials – antiferromagnetic materials – Ferrites and its applications

Unit - III Dielectric Materials Periods 9

Electrical susceptibility – dielectric constant – electronic, ionic, orientational and space charge polarization – frequency and temperature dependence of polarization – internal field – Claussius – Mosotti relation (derivation) – dielectric loss – dielectric breakdown – uses of dielectric materials (capacitor and transformer).

Unit - IV Thermoelectricity Periods 9

Seebeck effect, thermoelectric power, thermoelectric series, Peltier effect, Thomoson effect, measurement of temperature

using thermocouple, law of successive temperature, law of intermediate metal, application of Thermo electric properties.

Unit - V Modern Physics Periods 9

Dual nature of particles, Blackbody radiation, Wien's law, Photoelectric effect, Compton effect, de Broglie's hypothesis, electron diffraction, nuclear energy, mass energy relation, nuclear binding energy, nuc lear fission, nuclear power reactor, fast breeder reactor, nuclear fusion.

Total Periods 45

Course Outcome: The student will be able to

Distinguish different types of Semiconductors

Differentiate various magnetic materials Apply the concept of Dielectrics in their respective fields Differentiate various concepts of thermoelectricity. Apply concepts of modern physics in their respective fields

33

References:

1. R.K.Gaur, S.L.Gupta, Engineering Physics, Dhanpat Rai Publications Pvt Ltd, 2002

2. M.N.Avadhanulu, P.G.Kshirsagar, Engineering Physics, S.Chand Publications, 2012

Further Readings:

1. W.H.Hayt and J.A.Buck, Engineering Electromagnetics, Tata McGraw Hill, 2006.

2. Rajendran, V, „Materials science‟ Tata McGraw Hill, First reprint, 2012.

3. Mathew N.O. Sadiku (SAD), Elements of Electromagnetics, Oxford University Press,

2001.

34


(Autonomous Institution, Affiliated to Anna University, Chennai)


Programme B.E. Programme Code Regulation 2015

Department CSE,EEE,ECE,IT,BT Semester II



U15GE203 Basic Civil and Mechanical

Engineering 3 0 0 3 50 50 100

Course

Objective

To understand the basics of Civil Engineering and how to survey the area.

To know the various construction materials and its proper selection.

To understand the types and working principle of power plants. To study the various types and working principles of IC engines and pumps.

To understand the types and working principles of boilers and refrigeration and air conditioning systems.

Unit - I SURVEYING AND CIVIL ENGINEERING MATERIALS Periods 15

Surveying: Objects – types – classification – principles – measurements of distances – angles –leveling – determination of areas – illustrative examples. Civil Engineering Materials: Bricks – stones – sand – cement – concrete – steel sections.

Unit - II BUILDING COMPONENTS AND STRUCTURES Periods 15

Foundations: Types, Bearing capacity – Requirement of good foundations. Superstructure: Brick masonry – stone masonry – beams – columns – lintels – roofing – flooring – plastering – Mechanics – Internal and external forces – stress – strain – elasticity – Types of Bridges and Dams – Basics of Interior Design and Landscaping.

Unit - III POWER PLANT ENGINEERING Periods 10

Introduction, Classification of Power Plants – Working principle of steam, Gas, Diesel, Hydro-electric and Nuclear Power plants – Merits and Demerits – Pumps and turbines – working principle of Reciprocating pumps (single acting and double acting) – Centrifugal Pump.

Unit - IV IC ENGINES Periods 10

Internal combustion engines as automobile power plant – Working principle of Petrol and Diesel Engines – Four stroke and two stroke cycles – Comparison of four stroke and two stroke engines – Boiler as a power plant.

Unit - V REFRIGERATION AND AIR CONDITIONING SYSTEM Periods 10 Terminology of Refrigeration and Air Conditioning. Principle of vapour compression and absorption system – Layout of typical domestic refrigerator – Window and Split type room Air conditioner.

Total Periods 60

TEXT BOOKS:

1. Shanmugam G and Palanichamy M S, “Basic Civil and Mechanical Engineering”, Tata McGraw Hill Publishing Co., New Delhi, (1996).

2. Ramamrutham S., “Basic Civil Engineering”, Dhanpat Rai Publishing Co. (P) Ltd. (1999).

3. Seetharaman S., “Basic Civil Engineering”, Anuradha Agencies, (2005).

4. Venugopal K. and Prahu Raja V., “Basic Mechanical Engineering”, Anuradha Publishers, Kumbakonam, (2000).

35

5. Shantha Kumar S R J., “Basic Mechanical Engineering”, Hi-tech Publications, Mayiladuthurai,(2000).

Course Outcome

After learning the course the students can able to

Explain and prepare the area map, building plan and layout.

Explain the usage of construction material and proper selection of construction materials to design building structures.

Understand the energy sources and working principle of power plants and apply the knowledge of power plants to diagnose and solve the Engineering

problem.

Demonstrate working principles of petrol, diesel engine and pumps.

Explain the components of boilers, refrigeration and Air conditioning cycle.

36

VIVEKANANDHA COLLEGE OF ENGINEERING FOR WOMEN (Autonomous Institution Affiliated to Anna University Chennai)


Programme B.Tech Programme code Regulation 2015 Department BIOTECHNOLOGY Semester II

Course code Course name Periods / week Credit Maximum Marks


U15GE204 BIOCHEMICAL

THERMODYNAMICS

3 0 0 3 50 50 100

Course

Objective

The main objective of this course is to

Recall chemical reactions related to thermodynamics in biological processes.

Outline laws of thermodynamics. Investigate thermo bioenergetics

Evaluate bioprocess operations problems.

Unit - I INTRODUCTION TO THERMODYNAMICS

Periods 8+3

Generalised concept of Thermodynamics- Law of Thermodynamics,Enthalpy, Entropy, Free energy &Chemical Equilibria, Energy yield, Energy requiring reaction, Higher energy bonds & Compounds, Biological Oxidation- reduction recation, Energy yield, Energy requiring reaction

Unit - II

VOLUMETRIC PROPERTIES OF PURE LIQUID AND

GASES Periods 9+3

Volumetric properties of pure liquids: Equation of states- Ideal gas law-law of corresponding state-generalised compressibility factor with chart- behavior of liquids

Unit - III BASICS OF HEAT AND ITS APPLICATIONS

Periods 8+3

Heat effects- Heat capacities, equation and charts- Heat effect with and without phase changes- Standard heat of formation and combustion- Heat effect of industrial reaction

Unit - IV THERMODYNAMICS PROPERTIES OF FLUIDS Periods 10+3

Thermodynamics properties of fluids- Maxwell relation-Thermodynamic relations-Carnot cycle - Third law of Thermodynamics-Enthalpy & Entropy changes in ideal gases

Unit - V THERMO-BIOENERGETICS Periods 9+3

Thermodynamics and energetic of metabolic pathway, Oxygen requirement and Heat generation in aerobic growth, Energy Coupling (NADH and ATP) Thermodynamics of Oxidation-reduction reaction, Energetics of DNA- Protein Interaction, Protein folding and receptor- ligand binding

Total Periods 45+15

37

References 1. Sandler S.I. Chemical And Engineering Thermodynamics. John Wiley,4

th edition 2006.

2. Royels, JA, Kinetics and Energetics in Biotechnology, Elseviers, 2006

Further Readings

1. Smith J.M., Van Ness H.C., Abbot M.M. Chemical Engineering Thermodynamics. 6

th Edition. McGraw-Hill,

2001.

2. Narayanan K.V. A Text Book Of Chemical Engineering Thermodynamics. Prentice Hall India, 2001

Course Outcome:


Applying skills of thermodynamics in energy conversion.

Supports equilibrium calculations when two phases coexists in bacterial growth.

Design industrial equipments for bioprocess operations.

Formulate heat transfer equipments.

38


Elayampalayam, Tiruchengode – 637 205 Programme B.Tech Programme code Regulation 2015 Department BIOTECHNOLOGY Semester II

Course Code Course name Periods / week Credit Maximum Marks


U15CH203 BIOCHEMISTRY 3 0 0 3 50 50 100

Course

Objective


Familiarize different types of bio molecules,Classifications and its structure

Aquire knowledge in molecular structures and metabolic reactions.

Generalize theory nitrogen metabolisms.

Recognize the concepts and mechanism of contractile Proteins.

Cram knowledge about different types of energy compounds.

Unit - I INTRODUCTION TO BIOMOLECULES Periods 8 Types of functional groups, water, pH & buffers. Classification, functions and reactions of biomolecules: Carbohydra tes, Lipids, Proteins, Nucleic acids.

Unit - II METABOLISM OF CARBOHYDRATES & LIPIDS Periods 10

Glycolysis, TCA cycle, gluconeogenesis, pentose phosphate shunt, glyoxalate shunt, fatty acid synthesis and oxidation. Biosynthesis and degradation of Starch and Glycogen. Biosynthesis, degradation and regulation of Lipids.

Unit - III METABOLISM OF AMINO ACIDS

Periods 9

Nitrogen metabolism, Biosynthesis and degradation of all Amino acids, nucleotides. Metabolic disorders and

important molecules derived from amino acids, Interconnection of pathways and metabolic regulation.

Unit - IV STRUCTURAL PROTEINS & PROTEIN TRANSPORT Periods 9

Contractile proteins, Actin, myosin, mechanism of myosin ATPase activity, excitation- contraction coupling and relaxation, microtubules, microfilaments and their role in organelle movements.

Unit - V BIOENERGETICS Periods 9

High energy compounds, electronegative potential of compounds, respiratory chain, ATP cycle, calculation of ATP yield during oxidation of glucose and fatty acids.

Total Periods 45

References

5. Nelson, D.L. and M.M. Cox, “Lehninger‟s Principles of Biochemsitry”, 4

th Edition, W.H. Freemen &

Co., 2005. 6. Stryer, L., “Biochemsitry”, 4

th Edition, W.H. Freeman & Co., 2000.

Further Readings 4. Voet, D. and Voet, J.G., “Biochemistry”, 3

rd Edition, John Wiley & Sons Inc., 2004.

5. Murray, R.K., Granner, B.K., Mayes, P.A., Rodwell. V.W., Harper‟s Biochemistry, Prentice Hall International,2012

Course

Outcome

The students will be able to :

Understand different types of biomolecules and its structures.

Comprehend the pathway of various metabolisms related to carbohydrate and lipids.

Deduce different types amino acids and its interconnection pathways.

39

Apply structural properties and mechanism of proteins.

Analyze the yield of high energy compounds for Many metabolic reactions.

40


(Autonomous Institution, Affiliated to Anna University Chennai)



Department CSE, ECE, EEE, IT & Bio-Tech Semester II

Course

code Course name

Periods per week Credit Maximum Marks


U15PC101 PHYSICS AND CHEMISTRY

LABORATORY 0 0 4 2 50 50 100

Course

Objective

The main objective of this course is to :

Gain knowledge of dispersion of light.

Identify ultrasonic interferometer for measuring compressibility of liquid.

Understand elastic behavior of materials

Observe rigidity modulus of materials


PHYSICS 1. Determination of Young‟s modulus of the material – uniform bending. 2. Determination of dispersive power of a prism – Spectrometer 3. Determination of velocity of sound and compressibility of liquid – Ultrasonic interferometer. 4. Determination of the Rigidity modulus of the material- Torsional Pendulum. 5. Determination of band gap of the Semiconductor diode.

Total Periods 30

Course Outcome : The students will be able to

Understand unique nature of elastic property of a material.

Analyze Dispersive power of a prism.

Calculate compressibility of liquid.

Examine Rigidity modulus of the wire.

Estimate band gap of a semiconductors.

Course

Objective


Gather knowledge on harness producing salts and removal of hardness through estimation.

Collect the data required for dissolved oxygen present in water sample.

Employ the presence of chloride ion present in the given water sample.

Understand the alkalinity present in sample through neutralization reaction.


CHEMISTRY Periods 2

41

1. Determination of Total hardness, temporary and permanent hardness of water by EDTA method.

2. Estimation of Dissolved Oxygen content in water by Winkler‟s method.

3. Determination of chloride content of water sample by argentometric method (Mohr‟s method).

4. Estimation of alkalinity in water sample.

5. Estimation of available chlorine in bleaching powder.

Total Periods 30

Course Outcome :

The students will be able to :

Identify the hardness producing salts and removal of hardness through acid base reactions.

Calculate the amount of dissolved oxygen present in water sample and ensure that sample is fit for usage.

Estimate the presence of chloride through silver nitrate.

Evaluate the alkalinity present in sample through neutralization reaction.

42



Programme B.Tech Programme code Regulation 2015

Department BIOTECHNOLOGY Semester II



U15CH204 Biochemistry Laboratory 0 0 4 2 50 50 100

Course Objective: The main objective of this course is to:

Learn the principles behind the qualitative and quantitative estimation of Biomolecules.

Collect data required for analysis of the same in the body fluids.

_________________________________________________________________________________


1. pH measurements & Preparation of buffers

2. Qualitative test for Carbohydrates

3. Distinguishing reducing & non-reducing sugars

4. Using ninhydrin for distinguishing Imino & Amino acids

5. Protein estimation by Biuret & lowry‟s method

6. Protein estimation by Bradford colorimetric methods

7. Enzymatic assay of Phosphate

8. Extraction of lipids & analysis by TLC

9. Estimation of Cholestrol by Zak‟s methods

10. Estimation of nucleus end by absorbance at 260nm & hyperchromicity

TOTAL: 60 PERIODS

________________________________________________________________________________________

Course Outcome: The students will be able to :

Calculate amount of biomolecules present in the given sample

Estimate the amount of DNA salt through Spectrometric method.

43




Programme B.E./ B. Tech Programme code Regulation 2015

Department ECE , EEE &BT Semester

III

Course code Course Name Periods / Week Credit Maximum Marks


U15MA304 Complex Analysis and Partial

Differential Equations 4 0 0 4 50 50 100

Course

Objective

The Main Objective of the course is to Identify the skills of the students in areas of analyticity

understand and find Taylor’s series and determine their intervals of convergence and contour integral

Recognize to understand the concepts in Fourier series

Proficiently understand the skills of the students in the areas of transform techniques

Provide information in the areas of boundary value problems

Unit - I ANALYTIC FUNCTIONS Periods 9 + 3

Definition and properties of analytic functions, Cauchy-Riemann equations, Conformal mapping{ 1/z, z2} -

Bilinear transformations- Mapping of transformation w=1/z & w=z2.

Unit - II COMPLEX INTEGRATION Periods 9 + 3

Complex integration, Cauchy’s integral theorem and Cauchy’s integral formula and for Derivatives - Taylor’s

and Laurent’s Series. Singularities, Types of Singularities. Cauchy’s Residue Theorem .Evaluation of real

integrals( Unit Circle,Semi Circle excluding poles on real axis).

Unit - III FOURIER SERIES Periods 9 + 3

Periodic functions, Fourier series -Dirichlet’s condition- General Fourier series – Odd and Even functions-

Half range sine and cosine series- Parseval’s identity - Harmonic Analysis - Gibb’s Phenomenon .

Unit - IV FOURIER TRANSFORM Periods 9 + 3

Fourier integral theorem (without proof) – Fourier transform pair- Fourier transform of simple functions,Sine

and cosine transforms – Parseval’s identity,Evaluation of definite integrals.

Unit - V PARTIAL DIFFERENTIAL EQUATIONS Periods 9 + 3

Introduction to PDE, Classification of linear second order PDE in two variables, Modeling of one

dimensional wave equations, Solutions of one dimensional Heat and wave equations.

Total Periods: 60

Text Books / References:

1. E. Kreyszig, Advanced Engineering Mathematics (10th Edition), John Wiley (2015).

2. R. V. Churchill and J. W. Brown, Complex variables and applications (9th

Edition), McGraw-Hill

(2014).

3. R. V. Churchill and J. W. Brown, Fourier series and boundary value problems.(8th

Edition),

McGraw-Hill

44

Course

Outcome


Determine continuity , differentiability, analyticity of a function and find the derivative of the function

Evaluate a contour integral using fundamental theorem of calculus, Cauchy integral formula and compute the residue of a function ,find the Taylor’s series of a function, determine its circle or annulus of convergence.

Demonstrate the basic concepts in Fourier Series, properties , parseval’s identity.

Apply the concepts of Fourier Transform

Apply partial differential equation in engineering problems

45



Programme B. Tech Programme code 105 Regulation 2015

Department BIOTECHNOLOGY Semester

III



U15BT301 BIOPROCESS CALCULATION 3 0 2 4 50 50 100

Objective

The main objective of this course is to Analyze stoichiometric calculations in industrial applications

Recall humidity and solubility.

Investigate the chemical reactions among different states of matter.

Categorize steady and unsteady state processes.

Unit – I BASIC CHEMICAL CALCULATIONS Periods 8+3

Introduction - Conservation of mass and energy -Unit and its conversion: basic laws- stoichiometric calculations- Gases, Vapours, Liquids and Solids: Ideal gas law calculations, real gas relationships, vapour pressure and liquids, saturation, partial saturation - vapour-liquid equilibria

Unit – II HUMIDITY AND SOLUBILITY Periods 8+3

Humidity - Percentage Humidity, Relative Humidity, Molal Humidity, Cox Chart- saturation – vaporization - condensation - wet and dry bulb thermometry Solubility and Crystallisation, Dissolution – solubility of gases.

Unit – III MATERIAL BALANCES WITHOUT CHEMICAL

REACTIONS Periods 10+3

Overall and component material balances process flow sheet- Material balance without chemical reactions-Steady state and unsteady state- Recycle, bypass and purge

Unit – IV MATERIAL BALANCES WITH CHEMICAL

REACTIONS Periods 10+3

Material balance for steady and unsteady state processes with chemical reactions, multiple subsystems; Recycle, bypass and purge; Degrees of freedom-NTU- problems in Biotechnology industrial applications.

Unit – V ENERGY AND COMBUSTION BALANCE Periods 9+3

Energy balance – laws - heat capacity calculations-gas-liquid-fuel, enthalpy calculations- combustion calculations: fuel and flue gas analysis, air fuel ratio, theoretical oxygen, percentage excess air, limiting and excess reactant.

Total Periods 45+15

Textbooks

1 McCabe W.L., Smith J.C, Harriot P. ―Unit Operations In Chemical Engineering, 7th Edition. McGraw-Hill Inc., 2005

2 Geankoplis C.J. ―Transport Processes and Unit Operations, Prentice Hall India, 2002.

References

1 V.Venkataramani and N.Anantharaman,.Process Calculations Prentice Hall of India,Ltd, N.Delhi.2011

2 B. I. Bhatt and S. M. Vora, "Stoichiometry", 5th Edn., Tata McGraw Hill Publishers, 1996

Outcomes

Students who complete this course successfully are expected to

1. Evaluate unit operations of different states of matter.

2. Applying skills of material balance in industries.

3. Construct material balance process flow sheet for the effective unit processes to occur.

46





III



U15GE305 FLUID MECHANICS AND

MOMENTUM TRANSFER 3 0 0 3 50 50 100

Objective


Outline fluid flow properties for biochemical Processes.

Recall laws controlling motion of particles through fluids

Investigate mechanism of momentum transfer.

Evaluate hydrodynamics and flow characteristics needed in large scale industries.

Unit – I FLUID STATICS AND HYDRODYNAMICS

Periods 8+3

Fluid Statics and Its Applications Unit systems-conversion of units-Dimensional analysis-Basic concepts; fluid mechanics-hydrostatic equilibrium-application of fluid static s-manometers, continuous gravity decanter and centrifugal decanter.

Unit – II FLUID PROPERTIES

Periods 10+3

Fluid Flow Phenomena Rheological properties of fluids-laminar and turbulent flow-boundary layers; Basic equations of flow-continuity equation, Laminar and turbulent flow in pipes and channels. Mechanical energy equation-Bernoulli equation, pump work in Bernoulli equation.

Unit – III FLOW PAST IMMERSED BODIES

Periods 8+3

Flow past immersed bodies Drag and drag coefficients, flow through beds of solids-Ergun’s equation. Motion of particles through fluids-terminal velocity, Stoke’s law and Newton’s law. Hindered settling.

Unit – IV TRANSPORTATION OF FLUIDS Periods 10+3 Transportation and metering of fluids in P ipes, fittings and valves, pumps-power requirement, suction lift and

cavitation, positive displacement and centrifugal pumps. Measurement of flowing fluids-Venturi meter, orifice meter,

rotameter, pitot tube, magnetic flow meter

Unit – V MOMENTUM TRANSFER

Periods 9+3

Momentum transfer -Transport properties and mechanism of momentum transport. One dimensional transport in laminar flow.

Total Periods 45+15

Text books

1. McCabe,W.L, Smith,J.C and P.Harriot., Unit Operations of Chemical Engineering, 7

th Edn.,

McGraw Hill, 2005.

References

1. Fundamentals of Momentum, Heat and Mass Transfer (5th Ed.) J. Welty, C.E. Wicks, G.L. Rorrer, R.E. Wilson,2007

Outcomes Students who complete this course successfully are expected to

1. Design reactor for bio-based products to achieve the desired production and yield specification. 2. Lists flow properties and mechanism of fluid motion. 3. Formulate flow characteristic equipments. 4. Supports calculations of Bio-Heat and Mass Transfer operations in the upcoming semester.

47





III



U15BT302 GENETICS AND

MOLECULAR BIOLOGY 3 0 0 3 50 50 100

Objective


Recall basics of heredity, inheritance, mendelian principles of genetics and crossing over.

Discuss structure and molecular mechanism of genes.

Analyze the function of the genes at molecular level.

Evaluate regulation of gene expression in prokaryotes and eukaryotes.

Unit - I CLASSICAL GENETICS

Periods 8

Introduction and general background Reproduction as the basis of heredity; Mendelian principles of genetics, applications of Mendelian principles. Chromosomal basis of inheritance and linkage; Construction of genetic and physical maps; Linkage and crossing over, genetic mapping in eukaryotes and prokaryotes.

Unit - II GENE MUTATION

Periods 10

Chromosomal changes and gene mutations, types of mutations, consequences of mutations, occurrence and causes of mutations Genetic disorders and genetic counseling: Applications of genetics: Genetic advances in agriculture and medicine, eugenics.

Unit - III TRANSCRIPTION

Periods 8

DNA Replication in prokaryote and eukaryotes, enzymes and accessory proteins, telomere replication.DNA repair, mutagenesis. Transcription process in Prokaryote & Eukaryotes, regulation of transcription. RNA processing nuclear export and stability of mRNA

Unit - IV TRANSLATION Periods 9

Translation in prokaryote and eukaryotes, translational control , co and post translational modification of proteins

Unit - V REGULATION OF GENE EXPRESSION

Periods 10

Gene expression in prokaryote& eukaryote, operon model, genes silencing, transcription factors, antisense and ribozymes Various techniques of molecular biology, DNA cloning, genome sequencing.

Total Periods 45

Text books 1. Snustad, S., “Principles of Genetics”, John Wiley 7

th edition,2012

References

1. Klug, W.S. and Cummings, M.R., “Concepts of Genetics”, 10th

edition Pearson Education Incl,2012

2. Russel, P.J., “Genetics”, 6th Ed, Benjamin Cumming Comp. Inc,2004

48

Outcomes:

Students who complete this course successfully are expected to 1. Translate the structure of genetic materials to the function of the genes. 2. Lists gene mutations responsible for genetic disorders. 3. Differentiate transcription and translation mechanisms in prokaryotes and eukaryotes. 4. Analyze mechanisms of gene expression and develop new generation.

49






III

Course code Course name Periods/ week Credit Maximum Marks


U15BT303 MICROBIOLOGY 3 0 0 3 50 50 100

Objective


Recall history of microbiology, nomenclature of microorganisms and staining techniques.

Identify microbes, their structure, their metabolism and their industrial applications.

Analyze industrially important microbes and their effect in the environment.

Outline the production process of primary and secondary metabolites.

Unit – I INTRODUCTION

Periods 8

History of microbiology, Classification and nomenclature of microorganism, microscopic examination of microorganisms, light and electron microscopy; principles of different staining techniques like gram staining , acid fast, capsular staining, flagellar staining.

Unit – II MICROBES STRUCTURE AND MULTIPLICATION

Periods 10

Structural organization and multiplication of bacteria, viruses, algae and fungi with a special mention of life history yeast and bacteriophage.

Unit – III MICROBIAL NUTRITION, GROWTH AND

METABOLISM Periods 9

Nutritional requirements of bacteria and different media used for bacterial culture; growth curve, growth kinetics. Factors affecting growth and different methods to quantitate bacterial growth. Host-microbe interactions

Unit – IV CONTROL OF MICROORGANISMS

Periods 9

Physical and chemical control of microorganisms-Sterilization and disinfection- Dry heat, Moist heat, Filtration, Pasteurization , Radiation and Various chemical agents. Anti-bacterial, anti-fungal and anti-viral agents, mode of action and resistance

Unit – V INDUSTRIAL AND ENVIRONMENTAL

MICROBIOLOGY Periods 9

Production of penicillin alcohol, vit.b-12; biogas; bioremediation; leaching of ores by microorganisms; preservation of food. Bio-fertilizers and bio-pesticides; microorganisms and pollution control; biosensors. Recent advances in microbiology

Total Periods 45

Text books

1. DarnellJ., Lodish,H. and Baltimore, D., “Molecular Cell Biology”, W.H.Freeman & Co, 4th

edition 2000

References

1. Pelczar, M.J Chan and Krein Microbiology McGraw Hill 2007, 5

th edition

Outcomes:


1. Translate structure and biochemical aspects of various microbes. 2. Interpret microbial infections and their control in medical field. 3. Design microorganisms that can act in controlling food spoilage, leaching, pollution etc. 4. Examine problems related to culture contamination.

50





III

Course code Course name Periods / week Credit Maximum Marks


U15BT304 MICROBIOLOGY

LABORATORY

0 0 4 2 50 50 100

Objective


Develop skills of culture preparation.

Analyze sterilization techniques.

Identify microbes, their structure, their metabolism and their industrial applications.

Evaluation of parameters controlling microbial growth.

LIST OF EXPERIMENTS

1. Laboratory safety and sterilization techniques

2. Preparation of culture media – nutrient broth and nutrient agar

3. Culturing of microorganisms – in broth and in plates (pour plates, streak plates, Spread plate)

4. Staining techniques – grams’ and fungal

5. Quantization of microorganisms

6. Isolation of microorganisms from different sources – Soil and water

7. Physiological characteristics of Microorganisms using Carbohydrate fermentation test, IMVIC test,

Catalase Activity test, Oxidase activity test, Starch hydrolysis test.

8. Antibiotic sensitivity assay

9. Growth curve – observation and growth characteristics of bacteria

10.Effect of different parameters on bacterial growth (ph, temperature & UV irradiation)

Total periods : 60

Outcomes:


1. Investigate culture preparation for isolation and quantification of any bacteria 2. Solve problems with culture contamination. 3. Lists antibiotics influencing microbes, essential in diagnostics. 4. Create optimal conditions required for the bacterial growth.

51




Programme B.Tech Programme code 105 Regulation 2015


III

Course code Course name Periods/ week Credit Maximum Marks


U15BT305 MOLECULAR BIOLOGY

LABORATORY 0 0 4 2 50 50 100

Objective


Develop strategies for isolation of DNA & RNA.

Design competent cells

Analyze screening techniques for recombinants

Report recombinant plasmids by gel electrophoresis.

LIST OF EXPERIMENTS

1. Agarose gel electrophoresis

2. Isolation of bacterial Plasmid DNA

3. Isolation of bacterial Genomic DNA

4. Isolation of RNA

5. Restriction enzyme digestion

6. Ligation of digested DNA

7. Competent cells preparation

8. Transformation and screening for recombinants

9. SDS PAGE gel electrophoresis

Total periods : 60

Outcomes

Students who complete this course successfully are expected to 1. Define biochemistry of nucleic acids, proteins and identify central dogma. 2. Applying skills of isolation of DNA & RNA.

3. Solve problems related to screening of recombinant clones.

52





III



U15GE306

FLUID MECHANICS AND MOMENTUM TRANSFER

LABORATORY

0 0 4 2 50 50 100

Objective

The main objective of this ocurse is to

Outline the fluid properties for biochemical processes.

Recall laws controlling motion of particlesthrough fluids.

Investigate mechanism of momentum transfer.

Evaluate hydrodynamics and flow characteristics needed in large scale industries.

LIST OF EXPERIMENTS

1. Experiments on Reynolds apparatus for determination of flow regime and construction of fanning friction

factor vs. Reynolds No. plot

2. Determination of co.efficient of Discharge for Orifice meter

3. Determination of co.efficient of Discharge for venturi meter

4. Determination of co.efficient of Pitot tube and construction of velocity profile across the cross section of pipe

5. Determination of pressure drop for flow through packed bed and verification of Ergun equation

6. Experiment on Fluidization techniques and determination of

i) Minimum fluidization velocity

ii) Pressure drop profile

7. Determination of efficiency of a centrifugal pump

8. Pipeline assembling and a layout drawing with standard symbols

9. Calibration of a Rotameter

10. Determination of viscosity of Newtonian & Non-Newtonian fluid by Falling sphere method

Total periods : 60

Outcomes

Students who complete this course successfully are expected to 1. Ability to apply the skill of unit process of Fluid Mechanics 2. Ability to analyses the principles of fluid mechanics and its application of biological perspectives 3. Design and working principles of fluid moving machinery and transport phenomenon

53




Programme B.E / B.Tech. Programme code 105 Regulation 2015

Department BIOTECHNOLOGY Semester IV

Course Code Course name

Periods Per



U15MA405 Probability and Statistics 4 0 0 4 50 50 100

Course

Objective

The main objective of the course is to Proficiently understand the expected value, variance, and higher-order moments of

random variables (for both discrete and continuous types).

Analyze and interpret statistical data using appropriate probability distribution

Know and differentiate between one dimensional and Two dimensional random variables.

Identify and demonstrate suitable sampling and data collection process.

Identify testing of hypothesis for all size of samples.

Unit – I RANDOM VARIABLES Periods 12

Introduction to probability, random variables, probability distributions, moments, moment generating function,

Chebyshev inequality.

Unit – II SPECIAL DISTRIBUTIONS Periods 12

Special discrete and continuous distributions: Binomial and Poisson distributions, Uniform, Gaussian and

Exponential distributions. Function of a random variable.

Unit – III TWO DIMENSIONAL RANDOM VARIABLE Periods 12

Joint distributions, Marginal and Conditional distributions, Transformation of random variables, central limit

theorem.

Unit – IV ESTIMATION THEORY Periods 12

Sampling distributions, point estimation, unbiasedness, consistency, maximum likelihood estimation, Confidence

intervals for parameter in one sample from normal population ,

Unit – V TESTING OF HYPOTHESIS Periods 12

Testing of hypotheses for mean, variance using, t, F , chi-square distributions.

Total Periods 60

TEXT BOOKS:

1. Montgomery, John Wiley,“Applied Statistics and Probability for Engineers”, 5

th Edition, PHI Publications,

2003. 2. Dr.J. Ravichandran, “Probability and statistics for Engineers”, 1

st Edition, Wiley India Ltd, 2012.

REFERENCES: 1. Gupta S.C. and Kapoor V.K, “Fundamentals of Mathematical Statistics”, 1

st Edition, Sultan an Sons, 2001.

Course

Outcome


Translate the density and distribution functions for discrete and continuous variables.

Enable to identify various probability distributions.

Use the central limit theorem to compute probabilities.

Apply appropriate modern technology to explore probability/statistical concepts.

Ability to test the hypothesis using suitable statistical test

54





IV

Course code Course name Periods per



U15BT406 BIOPROCESS ENGINEERING 3 0 0 3 50 50 100

Objective


Recall the historical development of bio process technology.

Analyze the parameters to be monitored and controlled in fermentation process.

Evaluate the kinetics and thermodynamics of enzymatic process.

Interpret the kinetics and mechanism of microbial growth.

Unit – I PRINCIPLES OF ENZYME CATALYSIS Periods 8 Proteins as enzymes; Michaelis-Menten kinetics; Kinetics and Statistics; Inhibition; Effect of pH and temperature; Enzymology; Immobilized enzymes: methods, mass transfer considerations; Industrial enzymes

Unit – II FERMENTATION PROCESS Periods 9

General requirements, basic design and construction of fermenters and ancillaries; various commercial media for industrial fermentation; Sterilization of air, liquid media. Microbial biomass production - enzyme, Antibiotic and steroid fermentations, Aerobic and anaerobic fermentation processes; Solid state and submerged fermentation and their applications; Mixing in fermentation broths

Unit – III PROCESS DESIGN AND OPERATION OF BIOREACTORS Periods 10

Introduction to bioreactors; Operational modes of Bioreactors-Batch and Fed-batch bioreactors, Continuous bioreactors; Immobilized cells; Agitation and Aeration in Bioreactor; bioreactor strategies for maximizing product formation; bioprocess design considerations for plant and animal cell culture

Unit – IV MASS TRANSFER OPERATIONS AND BIOREACTOR SCALE –

UP Periods 10

Regime analysis of bioreactor processes, oxygen mass transfer in bioreactors - microbial oxygen demands; methods for the determination of mass transfer coefficients; mass transfer correlations. Scale up criteria for bioreactors based on oxygen transfer, power consumption and impeller tip speed.

Unit – V BIOSEPARATIONS Periods 8

Biomass removal; Biomass disruption; Separation techniques; Filtration, Centrifugation, Extraction; Adsorption and Chromatography.

Total Periods 45

Text books

1. Michael Shuler and Fikret Kargi, Bioprocess Engineering: Basic Concepts, 2nd Edition, Prentice Hall, Englewood Cliffs, NJ, 2005.

References 1 D.G.Rao,”Introduction to Biochemical Engineering” McGraw-Hill. 2005.

2 Stanbury,P.F.Whitaker,A&Hall,S.J , “Principles of fermentation Technology“, 2

nd Ed , Elsevier

Science Publishers, BV,Amsterdam. 2005.

Outcomes

Students who complete this course successfully are expected to Solve complex bioprocess engineering problems

Applying skills of reactors in chemical and bioprocess industries

Develop bio separation techniques

Design reactors for plant and animal cell culture.

55





IV



U15BT407 BIO-HEAT AND MASS

TRANSFER 3 0 0 3 50 50 100

Objective


Outline heat transfer properties used in industrial processes

Recall absorption, distillation and related equipments.

Investigate mechanism of mass transfer.

Evaluate absorption problems needed in large scale industries.

Unit – I MODE OF HEAT TRANSFER Periods 9 Steady state conduction; combined resistances; unsteady state conduction; lumped heat capacity; extended surfaces; combined conduction and convection

Unit – II HEAT TRANSFER MECHANISM Periods 9

Dimensional analysis; forced and natural convection; convection in flow over surfaces through pipes boiling and condensation.

Unit – III DIFFUSIONAL MASS TRANSFER

Periods 9

Molecular diffusion in fluids and solids; Inter phase Mass Transfer; Mass Transfer coefficients; Analogies in Transport Phenomenon

Unit – IV LIQUID – GAS SEPERATION

Periods 9

Principles of gas absorption; Single and Multi component absorption; Absorption with Chemical Reaction; Design principles of absorbers; Industrial absorbers; HTU, NTU concepts

Unit – V VAPOUR LIQUID OPERATION

Periods 9

V-L Equilibria; Simple, Steam and Flash Distillation; Continuous distillation; McCABE-THIELE & PONCHON-SAVARIT Principles; Industrial distillation equipments, HETP, HTU and NTU concepts.

Total Periods 45toii

Text books

1. McCabe,W.L, Smith,J.C and P.Harriot., Unit Operations of Chemical Engineering, Seventh Edn., McGraw Hill, 2005.

References

1. Geankoplis C.J. Transport Processes and Unit Operations. 3

rd edition, Prentice Hall of India, 2002

Outcomes


Design industrial equipments with desired heat transfer and mass transfer coefficients.

List transport phenomenon of fluids in industries.

Formulate heat transfer equipments.

Supports calculations of instrumentation and process control in the upcoming semester.

56





IV



U15ITE36 BIOINFORMATICS 3 0 0 3 50 50 100

Objective

The main objective of this course is to Recall function of database, data storage and data retrieval.

Categorize the software used to determine evolutionary distances.

Analyze mechanism of evolutionary relationship to treat genetic disorders.

Evaluate tools used for human genome project.

Unit – I INTRODUCTION & DATABASES Periods 8

Introduction, database model, raw database and processed database, data mining, data storage and retrieval,querying in database and tools for querying-BLAST, FASTA.

Unit – II PATTERN MATCHING & MACHINE LEARNING Periods 10

Gene finding, Hidden Markov Models (HMM), annotation of protein sequences, prediction of co-regulated genes from sequences. Sequence alignment-pairwise, substitution matrices, local, global, multiple sequence alignment, clustering, prediction

Unit – III PHYLOGENY Periods 10

Protein-protein interaction, protein chips, searching in databases, binding site prediction, phylogenetic tree analysis. Structural database –Protein structure database, homologous modeling. Comparison and superposition of structure

Unit – IV PROTEIN STRUCTURE AND SEQUENCING Periods 9

Comparison of distance matrices, searching of patterns and motifs. Evolution of Protein structure and sequence by comparing different organism

Unit – V ADVANCED TOPICS IN BIOINFORMATICS Periods 8

Human genome, introduction, Tools for Analysis, gene finding, probing with EST Exon microarray, database, functional genomics

Total Periods 45

Text books

1. Mount, D.W., “Bioinformatics: Sequence and Genome analysis”, Cold spring Harbour,2nd

edition 2004

References

1. Sensen,C.W, Essentials of Genomics and Bioinformatics 1st edition, John Wiley and sons,2002

Outcomes


1.Develop bioinformatics tools with programming skills 2.Applying skills of computational approach for biological perspectives 3. Design gene with desired mutation for treating genetic disorders. 4. Define diagnosis procedure based on computational approach.

57





IV



U15BT408 PROTEIN ENGINEERING 3 2 0 4 50 50 100

Objective

The main objective of this course is to Recall structure of aminoacids and the function of proteins.

Analyze bonding involved in the protein formation.

Interpret structure-function relationship of proteins.

Investigate protein sequence databases.

Unit – I INTRODUCTION TO PROTEINS AND PEPTIDES Periods 8+3 Amino acids as the building blocks of proteins, properties of amino acids. Different bonds in protein formation: Covalent, Ionic, Hydrogen, Coordinate, hydrophobic and Vanderwals interactions.

Unit – II PROTEIN ARCHITECTURE Periods 9+3 Primary structure, Secondary structure, Super-secondary structure, Tertiary structure, Quaternary structure. Ramachandran plot.

Unit – III STRUCTURE-FUNCTION RELATIONSHIP Periods 10+3

DNA-binding proteins: prokaryotic transcription factors, Helix-turn-Helix motif in DNA binding, Trp repressor, Eukaryotic transcription factors, Zn fingers, helix-turn helix motifs in homeodomain, Leucine zippers, Membrane proteins: General characteristics, Transmembrane segments, prediction, bacteriorhodopsin and Photosynthetic reaction center Immunoglobulins: IgG Light chain and heavy chain architecture, Abzymes & Enzymes: Serine proteases

Unit – IV TECHNIQUES IN PROTEIN ENGINEERING Periods 10+3

Strategies for protein engineering, Random and site-directed mutagenesis, Various PCR based strategies, Role of low

fidelity enzymes in protein engineering,Gene shuffling and Directed evolution of proteins, Protein backbone changes,

Antibody engineering, de novoprotein design.

Unit – V PROTEIN STRUCTURE ON THE WORLD WIDE WEB Periods 8+3 Protein sequence databases- Uni Prot, Swiss-Prot, PROSITE, Pfam. Protein structure databases- PDB, SCOP, CATH.

Total Periods 45+15

Text books

1. Voet D., Prat W.C., Voet J., “Principles of Biochemistry”, John Wiley and Sons, 4th

edition 2012.

2. Alberghina L., “Protein engineering in Industrial Biotechnology” CRC Press, 1st edition, 2000.

3. Branden C.Tooze J., “Introduction to protein structure”, Garland Publishing, NY, USA 2nd

edition, 1999.

References

1. Rawn D.J., “Principles of Biochemistry”, Prentice Hall, 3rd

edition, 2001.

2. Creighton T.E,” Proteins-Structures and Molecular properties”, WH Freeman, 2

nd edition 1993

Outcomes


Solve protein architecture for its effective function.

Design functional proteins in various fields of biotechnology.

Develop denovo protein with mutagenesis.

Applying skills of predicting protein structure.

58





IV



U15BT409

BIOPROCESS ENGINEERING

LABORATORY

0 0 4 2 50 50 100

Objective


Develop practical skills in enzyme isolation.

Evaluate enzyme kinetics.

Analyze BOD

Optimize growth medium and parameters influencing it.

LIST OF EXPERIMENTS

1.Growth of Bacteria - estimation of biomass, calculation of specific growth rate, yield Medium optimization coefficient

2. Growth of Yeast - estimation of biomass, calculation of specific growth rate, yield coefficient

3. Plackett Burman design

4. Medium optimization - response surface methodology

5. Enzyme kinetics - Michelis Menton parameters

6. Enzyme activity - effect of Temperature and pH

7. Enzyme inhibition kinetics

8. Enzyme immobilization - gel entrapment

9.Preparation of bioreactor, utilities for bioreactor operation

10. Biological Oxygen Demand

Total Periods: 60

Outcomes


Solve complex bioprocess engineering problems Applying skills of reactors in chemical and bioprocess industries

Develop bio separation techniques

Design reactors for plant and animal cell culture

59





IV

Course code

Course name Periods per



U15ITE37 BIOINFORMATICS

LABORATORY 0 0 4 2 50 50 100

Objective


Develop skills of database creation.

Analyze protein & DNA database with different tools.

Evaluate multiple sequence alignment tools.

Evaluation of parameters used for imaging.

LIST OF EXPERIMENTS

1.Introduction to UNIX basic commands and UNIX Filters.

2.Perl programming and applications to Bioinformatics.

•Basic scripting.

•Regular expressions.

•File i/o & control statement.

•Subroutines & functions.

•Writing scripts for automation.

3.Types of Biological Databases and Using it.

•Genbank.

•Protein Data Bank .

•Uniprot.

4.Sequence Analysis Tools

•Use of BLAST, FASTA (Nucleic Acids & Proteins).

•Use of Clustal W.

•Use of EMBOSS.

5. Phylogenetic Analysis

•Use of Phyllip.

6.Molecular Modeling

• Homology Modeling – Swiss modeller.

•Any Open Source Software Total Periods : 60

Outcomes

Students who complete this course successfully are expected to 1.Develop bioinformatics tools with programming skills 2.Applying skills of computational approach for biological perspectives 3. Construct evolutionary tree by calculating phylogenetic relationship. 4.design molecular 3-D relationship between organisms.

60





IV



U15BT410 BIO-HEAT AND MASS

TRANSFER LABORATORY 0 0 4 2 50 50 100

Objective


Outline heat transfer properties used in industrial processes

Recall absorption, distillation and related equipments.

Investigate mechanism of mass transfer.

Evaluate absorption problems needed in large scale industries.

LIST OF EXPERIMENTS

1.Shell and Tube Heat Exchanger

2. Simple Distillation

3. Steam Distillation

4. Packed bed Distillation

5.L-L Extraction

6. Leaching Studies

7.Adsorption Studies

8.Drying Studies

9. Plate & frame filter press

10. Rotary drum filter

Total Periods :60

Outcomes


Characterise adsorption phenomenon.

Develop distillation and drying equipments.

Design of growth kinetics and enzyme kinetics.

Solve heat transfer derivations

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