vol. new productsdownloads.hindawi.com/journals/jamc/1988/325813.pdfdata-base can be used for acid,...

Journal of Automatic Chemistry, Vol. 10, No. 2 (April-June 1988), pp. 111-119

New products

Gas chromatograph

The 8700 GC offers simultaneousdual channel operation with a fullcolour VDU for enhanced userinteraction. Powerful integral dataprocessing, with multi-level calibra-tion and multiple reference peakfacilities, easily handles the most

complex chromatography, makingthe instrument ideal for researchenvironments as well .as routineanalysis.

Features include:

Single or simultaneous dual chan-nel chromatographic operation.

Full colour VDU with softkey userinteraction.

Dual-channel real-time or postrun graphics, split screen or over-laid.

Simple graphics manipulation forcomparison of sample and refer-ence chromatograms.Enhanced software for indepen-dent integration of both channels,multi-level calibration, and mul-tiple reference peaks, with re-integration facilities.

Computer communications fortransfer of GC methods, raw andre-integrated data and reports.

Fully automated, analyticalsequencing software is included asstandard for routine applications.

For further information contact Perkin-Elmer Ltd, Post Office Lane, Beacons-field, Buckinghamshire HP9 1QA, UK.

Centrifuge brochure

Beckman’s range of GP series centri-fuges is described in an illustratedbrochure. There is a choice ofmodelsthat fit under, as well as on top of,the laboratory bench, and the GPcentrifuges offer a 3-1itre capacity,3750 rpm/3200 g with horizontalrotor or 6400 rpm/5642 g with fixedangle versions, automatic soft-startand two-stage disc brake for rapidbut gentle acceleration.

Modular disc adapters are availablefor every popular sized tube and theGP is the first compact centrifugeable to run 250 ml conical-tip tissueculture bottles- up to four per run inspecial sleeves. It also spins 750 ml,500 ml and general 250 ml bottlesand accommodates up to eight 96-well microplates as well as blood bagcups for single, double, triple andquad packs and aerosol canisters,with bucket covers to contain brokentubes. Each model is available withor without refrigeration.

Further information from Beckman Ltd,Progress Road, Sands Industrial Estate,High Wycombe, Buckinghamshire, UK.Tel.: 0494 41181.

Dual target sample introductionprobe

Fast atom boxnbardment mass spec-trometry (FAB-MS) is an indispens-able technique for the analysis ofthermolabile, non-volatile com-pounds and polar compounds. Accu-rate mass measurement by conven-tional FAB-MS has been made bymixing the internal reference sample,sample and matrix materials at asuitable ratio and placing the mix-ture on a single sample target of theFAB probe. However, as the ioniza-tion efficiency of the sample cannotbe known in advance, the adjustmentof the optimum concentration ratiobetween the sample and internalreference sample must be made bytrial and error.

A new dual target FAB probe hasbeen developed by Jeol Ltd to over-come such problems.

The probe tip has two faces which areloaded with two different samples,which can be measured by rotatingthe probe by 180 One face is loadedwith an unknown sample and theother with a reference sample, andthe target face is changed over alter-nately at each scan. This probe canmeasure inorganic salts such as cae-sium iodide as the reference sample,

and permits mass measurement in ahigh mass range above m/z 1500,which has not been possible by theconventional method.

The new probe is described in twoapplication papers available fromJeol. Work detailed includes massmeasurements on compounds withmolecular weights of 362"2 to 1857"9.These include angiotensin-1 andgamma-endorphin, hydrocortisone,erythromycin, alpha-cyclodextrin,bradykinine, bracitracin A andalpha-MSH.

Details of the new probe and copies of thepapers are available from Jeol Ltd, JeolHouse, Grove Park, Colindale, LondonNW9 0JN, UK. Tel.: O1 205 6376.

Sample scheduler software

It is a routine requirement for anyanalytical laboratory concerned withproduction control, to have a pres-cribed schedule of sampling times,dates and locations. Similarly, healthcontrol and water control labora-tories need to know when and whereto collect samples. Perkin-Elmer hasnow released software, the samplescheduler package, to fully automatethis aspect of laboratory informationmanagement. The sample schedulerpackage is an enhancement packageto Perkin-Elmer’s laboratory infor-mation management system (LIMS000).

The major features of the samplesheduler package are:

A spreadsheet format diary: allow-ing a laboratory to specify, up to ayear in advance, when a sampleshould be taken from which sam-pling point and which tests are tobe performed at the samplingpoint or in the laboratory. Sam-pling points could be riverstations, soil areas or, on com-pletion of certain reactions, withina multi-stage chemical process.

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New products

Collection lists: indicating whenand from where the samples aredue for collection. These can beproduced at any time, again up toa year in advance if necessary, andwith optional labels to attach to

samples at time of collection.

Sample receipt: an autoschedulingfeature works overnight to searchthe computer data-base for all thesamples expected the next day andcreates a current file for them.This saves the analyst time whenlogging samples on to the system.The software can cope withsamples that have been lost or willbe sampled at a later date out ofsequence.

From scheduling sample collection to

report generation, the LIMS 2000family provides a total solution toinformation management problems.

For further information contactPerkin-Elmer Ltd, Post Office Lane,Beaconsfield, Buckinghamshire HP91QA, uI.

Sample manipulation

Applied Research Laboratories(ARL) has .announced two systems

for the automatic manipulation ofsamples. The SMS-100 and SMS-200 are standard extensions of theARL 3460 optical emission spectro-meter and both provide a fully auto-matic instrument operation eliminat-ing the need for operators to handlesamples.

The SMS systems provide the follow-ing automatic facilities"

Sample preparation.

Sample transport to the spec-trometer spark stand.

Sample analysis.

Sample filing following analysis.

Cleaning of electrode and sparkstand table.

Instrument standardization(option).

Check of instrument operationusing control samples (option).

The more sophisticated version, theSMS-200, employs one of the mostadvanced industrial robots on themarket. The smaller SMS-100 ver-sion is equipped with a proven andwidely accepted industrial robot cap-able of handling up to 40 sampleanalyses per hour.

Each robot possesses an armlikeflame and stands on a subframewhich is linked electrically andmechanically to the spectrometer.

The spectrometer equipped with anSMS-100 or SMS-200 system can beused in various environments. Forexample"

In close proximity to the produc-tion process, installed in a cabin or

shelter (local laboratory version).

In a central laboratory, remote

from the production process. Inthis case, the user needs to install along distance automatic sampletransport and preparation systemto achieve complete automation(central laboratory version).

In fully automatic operation, theSMS-200 can handle as many as 60sample analyses per hour; far morethan any operator could sustain overa working shift.

Apart from the savings in manpowerwhich can be achieved by employingthe SMS-100 or SMS-200 samplemanipulation systems, further reduc-tions in production costs are obtainedbecause the systems:

ARL Applied Research Laboralories SA (Ecublens, Switzerland) have announced the SMS-IO0 and SMS-200 in thezr spectrographer’snewspaper ’ARL News’.

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New products

Reduce the response time betweensampling and availability of thesample analysis.

Increase the sample analysiscadence.

Increase overall reliability byeliminating possible humanerror.

All result in an increased return onthe spectrometer investment,improved laboratory productivityand short payback period.

Details from ARL Applied ResearchLaboratories SA, En Vallaire, CH 1024Ecublens, Switzerland. Tel.: 02134 97 01.

Quality control

The quality control laboratory is thekey element in ensuring that pro-ducts conform to specifications,internal limits and possible legisla-tive requirements. QCLIMS is alaboratory information managementsystem designed by Perkin-Elmer toassist specifically in maintaining pro-duct quality in the pharmaceutical,cosmetic and food and drink indus-tries.

It has been successfully installed atsites in the UK, Europe and NorthAmerica, feedback of ideas from thecustomer base has assisted Perkin-Elmer in the development ofQCLIMS revision 1.1.

QCLIMS revision 1.1 is an enhancedversion ofthis popular software pack-age. It contains substantiallyincreased functionality and providesthe user with a well structured andsound product which has beenengineered in line with good labora-tory practices. This means that lab-oratory personnel can maintain a

great degree of confidence in theiranalytical results as well as in thedecisions derived from such data.

The core of the system is theQCLIMS database, which is dividedinto a number of data sets. Thesecontain details of samples, tests, spe-cifications and other informationnecessary to run the system. Theconfiguration of the database is flex-ible and data sets can be defined tomeet the needs of laboratory andproduction personnel.

The ’applications’ software is ofmodular design and performs opera-tions from specification managementand sample log-in to results entryand certificate of analysis produc-tion. QCLIMS provides the means to

effectively control information gener-ated in the laboratory and so whiledata is organized, skilled laboratoryanalysts are freed to analyse thesamples.

QCLIMS revision 1.1 featuresenhancements to most of the applica-tion modules and operates with theLIMS 2000 software on a wide rangeof Perkin-Elmer 32-bit minicomput-ers. Any suitably configured IBM PCor compatible can also be incorpor-ated into the QCLIMS system towork as a text and graphics terminaland provide a system which has thebenefits of both a centralized data-base and distributed processing.

Further details from Perkin-Elmer Ltd,Post Office Lane, Beaconsfield, Bucking-hamshire HP9 1QA UK. Tel.: 049466161.

Fluorescence detectors

Severn Analytical, the UK’s largestindependent supplier of HPLC andSFC instrumentation have intro-duced a new range of fluorescencedetectors- the FD series.

All competitively priced, the instru-ments greatly enhance Severn’scapability as a specialist supplier ofdetectors for HPLC.

The three instruments in the rangeall feature a powerful 10 W xenonflash source and are designed for thefast and convenient interchange offlow cells and cuvettes for microbore,analytical and preparative applica-tions. Measurements of non-flowingsamples, such as those from fractioncollectors, can be taken with acuvette accessory.

The FD-100 is an advanced filterfluorimeter with a wide selection ofthe highest quality excitation andemission filters which can be inter-changed in seconds.

The FD-200 features the combina-tion of a high efficiency monochro-mator for excitation and emissionfilters common to the FD- 100.

The top-of-the-range FD-300 is a.dual monochromator instrument,with continuously variable excitationand emission wavelengths. Incorpor-ating high throughput monochroma-tors and offering low stray light, it isan ideal detector for applicationswhere the excitation and emissionwavelengths are closely separated.

The detectors will find applicationsin many areas, including phar-maceutical analysis, food analysis,clinical assays, organic synthesis andpolymer/plastics analyses.

For further technical information contactDave Green, Severn Analytical Limited,Unit 2b, St Francis’ Way, SheffordIndustrial Park, Shefford, BedfordshireSG17 5DZ, UK. Tel.: 0462 816406.

Titrator

With a built-in data-base of 15 stan-dard methods, the new Mettler DL25titrator is suitable for both routinework and for development. This tit-rator has significant advantages, par-ticularly for analytical laboratoriesthat require precise, clear, resultsquickly.

The 15 standard methods held in thedata-base can be used for acid, baseand redox titrations, non-aqueous orphotometric titrations, and also forthe determination of chlorides. TheDL25 titrates automatically to twoendpoints or to equivalent points; itdetermines p- and m- values, pHvalues, TAN/TBN values (total acidand total base numbers) according toASTM/DIN, calculates half-neutral-ization value (HNV) and carries outpH stat and back titrations.

In all cases where the standardmethods, although optimized inmany practical trials, do not exactlymeet the user’s requirements, themethod can be adapted to the par-ticular application with configura-tion parameters entered in a dialoguewith the DL25. These standardmethods can then be stored in aspecial memory which will hold up to50 methods. A code prevents themethod parameters from beingaltered accidentally.

Mettler balances can be connectedfor transferring sample weights auto-matically. A Mettler GA44 printer or

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New products

a commercial dot matrix graphicsprinter then logs the titration data indetail. The Mettler ST20 samplechanger (optional) or robots or com-

puters can also be connected.

More information from MettlerInstrumente A G, CH 8606 Greifensee,Switzerland.

Binary gradient controller

The Aston LC controller is a binarygradient controller, which is compat-ible with most stand-alone LCpumps. Gradient profiles and timedevents schedule are created on thegraphics screen of an IBM or com-

patible PC. Methods can be storedon disk and then downloaded to thecontroller where its battery backedRAM storage means that they arc

always available for use.

Gradient programs are powerful,allowing up to 10 segments, each ofwhich can have a different profile andflow rate. The controller integrateswell with automated systems andprovides appropriate handshakingsignals for other equipment.

With a method in the controller’smemory, the PC may be disconnec-ted, an LCD and status lights on thecontroller providing information tothe chromatographer on the method,status and chromatographic condi-tions.

Revision to Lab Manager

CALS Lab Manager Revision 6.0, anintegrated laboratory informationmanagement system (LIMS), is nowavailable from Beckman. Revision6.0 is the current release version ofLab Manager software for DECVAX and H-P computers. It con-tains many enhancements and muchnew functionality suggested by thelarge, active CALS User Group.

Revision 6.0 provides users with totalfull screen data entry and executionof most functions. Full screen opera-tion can be described as a ’fill in theblanks’ approach to a computerinterface, similar to entering data ona blank form in a laboratory note-

book. This capacity makes LabManager Revision 6.0 simple to use,thus reducing the personnel trainingburden.

In previous Lab Manager softwarerevisions, functions for sample log-in,testing and validation were perfor-med by the full screen mode ofoperation. Revision 6.0 extends thiscapability to approval, entry ofretests and dictionary maintenance.Test definitions, product specifica-tions, calculations and test schedu-ling may be maintained and updatedon-line. Review and approval of allsuch changes may be required beforeputting them into use. All previoustest specifications, product specifica-tions and other dictionary entries can

Outputs are available on the con-troller to drive most modern fre-quency, analogue or RS232 drivenpumps and now it is possible toassemble a gradient HPLC systemusing two pumps from different man-ufacturers.

The Aston LC controller requires aPC or compatible with 512K RAMand CGA, EGA or Hercules graph-ics, and an RS232 interface. As alimited period introductory promo-tion Aston Scientific will be shippingthe controller with a free AmstradPPC640 portable PC.

For further information contact MarlinPerry, Aston Scientific Ltd, 49 LongPlough, Aston Clinton, BuckinghamshireHP22 5HD UK. Tel.: 0296 630304.

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The new chromatography integrator from Hewlelt-Packard (HP 3396A), which offers a

full range orfunctions for less than 1500. For this price, it provides wide-rangingcapabilities including storage and re-plolting of chromatograms, negalive peak handling,ESTD% reporting, mulli-level calibration, method storage and automation. A singleintegrated circuit board contains all system electronics, and the integralor can be used tocontrol and implement a complete analysis, and to generate and annotate reports. Fullinformation from the Analytical Instrumentation Group, Hewlett-Packard Ltd, MillerHouse, The Ring, Bracknell, Berkshire RG12 1XN, UK.

New products

be maintained on-line for reviewwhere laboratories are subject tocompliance with government regula-tions. All changes are recorded- whomade the change and the time anddate.

Lab Manager Revision 6.0 alsoimproves data output. Users mayscroll or pan the screen horizontally.Report commands are now permittedwith full screen data entry. LabManager Revision 6.0 offers the abil-ity to add AUTOLOG, an optionalsoftware package for automatic sam-ple log-in; it is especially useful forapplications where a multitude ofsamples are generated on a periodic-ally scheduled basis, such as chem-ical processing plants.

For additional information, specificationsor a demonstration, contact: John Boother,Laboratory Automation Operations, Beck-man RHC Ltd, Progress Road, SandsIndustrial Estate, High Wycombe, Buck-inghamshire HP12 4JL, UK. Tel.: 049441181.

Metrohm and Howe

From January Metrohm equip-ment will be sold in the UK by V. A.Howe & Company Ltd. A cataloguedescribing Metrohm’s products isnow available from Howe. The rangeincludes:

Dispensers and diluters.

’Titroprocessors’.

Karl Fischer titrators.

Ion chromatographs.Photometers.

Conductometers.

pH, redox and ion meters.

Howe are backing up the dealershipwith seminars, service contracts,applications advise and a users’ club.

Copies of the catalogue from V. A. Howe& Co. Ltd, 12-14 St Ann’s Crescent,London SW18 2LS. Tel.: 01 874 0422.

Atomic absorption spectrophoto-meter

The model 5100 is a fully automatedmulti-element system for any AAapplication and is optimized for

flame, furnace and mercury/hydridesampling. It will readily performboth conventional flame and furnaceAA, as well as Zeeman-correctedgraphite furnace analysis.

The Model 5100 PC has been de-signed to be easy to use. Thecolour software works within a GEMenvironment and control of theinstrument is via a mouse pointerand function keys. Drop-downmenus, and multiple windows pro-viding between one and five simul-

taneous ’views’ into the system, offermaximum versatility with peak per-formance.

The 5100 PC system uses an IBM offully compatible PC and includes afull complement ofo.ptions and acces-sories to expand system capability asanalytical needs change.

For further information, contact Perkin-Elmer Ltd, Post Office Lane, Beacons-feld, Buckinghamshire HP9 1QA, UK.Tel.: 04946 6161.

Linear Instruments Corporation has introduced its high speed UV-Vis HPLC detector,Model 206, which is designed to out-perform the more expensive Photodiode Array (PDA)HPLC detectors. The Model 206 can monitor 32 diffirent wavelengths simultaneouslyduring the running of a chromatogram, and can provide chromatogram tracings at fourselected wavelengths, including on the fly spectra.

Using a high speed grating drive mechanism, the detector can achieve sensitivity levels abovethose achieved by PDA units.

The Model 206 is entirely user programmable in simple, easy to understand language.

The Model 206 uses Linear’s complete line of externally mounted Jlow cells, including:capillary, microbore, analytical, semi-preparative and variable pathlength preparative cell.

The operating range of the instument is 190-800 nm, and it is priced well under $10 000.

For complete information, contact Linear Instruments Corporation, 500 Edison Way, Reno,Nevada 89502, USA. Tel.: 702 786 3636.

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New products

Integration for chromatography

Severn Analytical have introducedthe Chromatocorder 12, a low-costsingle channel integrator for chro-matography. The integrator is com-patible with any GC, LC, SFC orTLC. Although compact it incorpor-ates an integral full-width printer/plotter. Remote control and long-term power fail memory back up arealso included as standard.

Key features of the instrument arethe extensive ’Help’ messages de-signed to improve ease-of-use, andchromatogram storage and replaywith base-line construction and nam-ing of peaks.

To further expand its capability thereis an optional program available forGPC applications, and an optionaltwin 31/2 in disk drive for increaseddata storage.

For further technical information contactDave Green, Severn Analytical Ltd, Unit2B St Francis Way, Shefloral IndustrialPark, Shefford, Bedfordshire SG17 5DZ,UK. Tel.: 0462 816406.

Controlled stress rheometer

The CarriMed controlled stressrheometer is a computer controlledinstrument capable of characterizingthe flow properties ofsubstances withcomplex rheologies. It has applica-tions in the formulation of cosmetics,pharmaceuticals, foodstuffs, paintsand inks.

The rheometer works on the con-trolled stress principle. In addition tostandard measurements that can bemade on a rotational controlled-shear rate instrument, it is suited tostudies on materials at rest, inter-actions between phases and mol-ecular interactions. Moreover, stresscontrolled situations, such as thesettling of suspensions, film levelling,and flow under gravity, can be simu-lated.

Operating modes include creep andoscillation tests, plus controlledstress and controlled shear flowmodes. The instrument can handle awide range of samples, includingvisco-elastic inks, thixotropic paints,fibrous and heterogeneous foodstuffs,

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Autochrom, Inc. ’s HPLC controller.

and relatively delicate low viscositybiological fluids and polymer solu-tions.

The user can choose sensors withdifferent measuring geometries tosuit the characteristics and size of hissample. Configurations include coneand plate, parallel plates, concentricand double-gap concentric cylindersand special designs for surface rheol-ogy and fibre testing.

Temperatures between 8C and60 C can be handled without a water

bath; this can be extended to a rangeof 100 C to 300 C.

Mechanically more simple than arotational rheometer, the same con-trolled stress system can be appliedto many different substances simplyby software changes. Experimentalvariables can be stored in the com-puter and set for a given experiment.Once set-up, the full rheologicalcharacterization is handled entirelyby the computer.

The controlled stress rheometer cancharacterize the flow behaviour ofboth high and low viscosity materialsfrom 2"5 x 10.2 mPasec to 2"5 x 109mPasec. Shear rates can be measuredfrom 5 109 to readings of 10-:’

sec--1 and below, depending upon thegeometry and technique applied.

Further details are availablefrom Mrs SueChick, Carri-Med Ltd, GlebelandsCentre, Vincent Lane, Dorking, Surrey,UK. Tel.: 0306 886180. The US dislribu-tot is MiTech Corporation.

HPLC gradient/system controller

The Autochrom Model 300 family ofHPLC controllers upgrade existingisocratic HPLC systems. The Model300 family of controllers blend up tothree solvents using one pump or twosolvents using two pumps. Prop-rietary proportioning algorithms(AAPT) can upgrade pumps to pro-vide gradient accuracy and repeatab-ility comparable to integrated solventdelivery systems costing two to threetimes more. Four curve types,battery-backed memory, and sixexternal events expand the versa-

tility. Configurations tbr eitherstand-alone or computer-basedHPLC systems are available.

Details from Autochrom, Inc., PO Box207, Milford, Massachusetts 01757,USA. Tel.: 617 478 2670.

Enzyme-linked HPLC

The combination of an enzyme-linked assay and HPLC is a simpleroutine method to analyse acetyl-

New products

choline and choline in the p molrange. These are separated by HPLCand then passed through the enzyme-reactor, where hydrolysis of acetyl-choline, oxidation of choline andformation of H202 take place. TheH202 is then measured by the elec-trochemical detector. Complicatedextraction and concentration proce-dures (for instance for the analysis oftissue homogenates) are unneces-sary. There is no loss in enzymeactivity for several months in con-tinuous mode action.

More information from Biometra, Biome-dizinische Analytik GmbH, Wagenstieg 5,D 3400 Gittingen, FR Germany.

Amino-acid analysis

Beckman’s recently introducedSystem Gold Personal Chromato-graph is now available in a specialconfiguration for amino-acid analy-sis. Ion exchange chromatographycan be used with this system andthere is a choice of ion exchangecolumns for separating eitherphysiological fluids or hydrolysates.

For results that are unaffected bysample matrix or derivative stabilityduring separation, the System Goldchromatograph uses cation exchangewith ninhydrin post-column deriviti-zation and detection at 500 nm. Thismethod separates and detects allamino-acids in a single process.

The system can also be easily con-figured for high-sensitivity binarygradient analysis of PTH, PTC andOPA derivatives using the com-pany’s Ultrasphere columns.

The user controls the System Goldpersonal chromatograph for amino-acid analysis with an IBM PC-XT,PC-AT or PS 2 model computer, andviews chromatograms, integrationdata and system status on themonochrome or colour screen. Thesystem’s autosampler handles up to80 samples with injection volumesfrom to 250 tl programmable in 1increments. The UV/VIS detector isfully programmable and includes atungsten source and a post column

reactor are also included in thesystem.

Details from Beckman Ltd, ProgressRoad, Sands Industrial Estate, HighWycombe, Buckinghamshire, UK. Tel.:0494 41181.

Atomic spectrometers

A new four page colour mini-catal-ogue for atomic absorption spectro-photometers, sequential and simul-taneous ICAP spectrometers, arc/spark direct reading emission spec-trometers, and solid samplingplasma spectrometers was publishedin January by Thermo Jarrell Ash,Franklin, MA. The catalogue isintended to provide spectroscopicinformation to analytical labora-tories performing elemental analysesranging from the analyses of metal

castings, to the analyses of a fewdozen solution samples a week forone or two trace metals, to theroutine determination of large num-bers of elements in hundreds ofsamples a day.

Copiesfrom ThermoJarrell Ash, 8E ForgeParkway, Franklin, Massachusetts 02038,USA. Tel.: 617 520 1880.

Applications bibliography

Over 500 articles and procedures,which cite the use of Analytichemsolid phase extraction products in theextraction and purification of a widevariety ofchemical compounds foundin biomedical, clinical, environmen-tal, food and general industrial appli-cations, are listed in Analytichem’sapplications biography, published inJanuary 1988.

Each entry lists the complete refer-ence, as well as the compounds ofinterest, the matrix from which theisolates were extracted, the method offinal analysis and the type ofAnalyti-chem sorbent used.

The company’s Bond Elut, BondElut LRC and Chem Elut and ToxElut extraction columns can solvetime-consuming sample preparationproblems by extracting, purifyingand concentrating compounds ofinterest in minutes instead of hours.

The bibliography highlights analy-tical methods using solid phaseextraction in conjunction with a

variety of analytical techniques.These include HPLC, GC, GC/MS,UV spectroscopy, ion selective elec-trode analysis, RIA, enzyme immu-noassay NMR, LC/MS and TLC.

More informationfrom Analytichem Inter-national, PO Box 234, CambridgeCB2 1PE, UK. Tel.: 0223 328177.

pH/blood gas analysers

An improved family of pH/blood gasanalysers from Instrumentation Lab-oratory (IL) offers a choice of sam-pling modes that now includes sam-ple injectioin, as well as aspirationfrom all common containers. In addi-tion a ’Help key’ has been added tosimplify operation and troubleshoot-ing.

The ’Help key’ is now available onIL’s mid-priced System 1306 analyser.The key provides instant access tosome 40 different ’help’ messages. Aswell as diagnosing any problem, itprovides directions on the variousoperating modes, such as explaininghow to turn certain parameters on oroff. It even knows if the unit isinterfaced with an IL CO-Oximeter.The ’Help key’ feature is available infive languages.

A brochure describing the pH/blood gasanalysers is availablefrom InstrumentationLaboratory, 113 Hartwell Avenue, Lexing-ton, Massachusetts 02173, USA. Tel.: 617861 0710, orfrom Instrumentation Labora-tory SpA, Milan, Italy. Tel: 39 2 25221.

Chiramonitor

Recent developments in the monitor-ing ofoptically active compounds hasshown the need for a universalmethod of quantitatively detectingchiral enantiomers ofdrugs and otherpharmaceutical formulations. Enan-tiomers can show therapeutic proper-ties in one isomer, whilst the other istoxic.

The Chiramonitor, manufactured byApplied Chromatography Systems,will detect any compounds showingoptical activity. The detector is sensi-

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New products

tive down to ngm levels and linearover wide concentration levels.

A laser source, coupled with a photo-diode detection system, allowsaccurate and reproducible HPLCanalysis.

By using enantiomer ratioing proce-dures, it is possible to analyse theexact concentrations of enantiomers,without the requirement for separa-tion. Thus, expensive and specificchiral columns are not necessary insome applications.

Details from Applied ChromatographySystems, Heapy Street, Macclesfield,Cheshire SK11 7JB, UK.Tel.: 0625 34575.

IL Test reagents

New IL Test reagents for CK/CPK,uric acid, cholesterol and ALT/SGPT have been introduced byInstrumentation Laboratory (IL) forthe Monarch chemistry system

The new reagents offer increasedon-board stability, improved linear-ity and faster assay time, resulting inmore tests per kit, lower cost per testand faster turn-around of test results.

The new IL Test for CK/CPK is anNAC activated procedure with anexpected range of 14-156 U/1 at30C. It has a reconstituted life ofseven days at 2-6 C and is linear to1800 U/1. Assay time has beenreduced to less than 5 min.

The new IL Test for uric acid is asingle reagent procedure with recon-stituted stability of two months at2-6C and linearity to 20 mg/dl.

The new IL Test for cholesterol usesa concentrated liquid reagent withopen container stability for 30 days at2-25C. This 4-min assay requiresonly 50 tl of reagent per test.

The IL Test reagent for ALT/SGPThas a reconstituted stability of 14days at 2-15 C.

The new IL Test reagents are pack-aged in easy-to-use, prefilled BoatILcontainers which are loaded directlyinto the Monarch Chemistry System.Containers are bar-coded so the

system can identify them automatic-ally.

For a detailed brochure, contact Instrumen-tation Laboratory, Lexington, MA 02173,USA. Tel: 617 861-0710. Tlx: 92-3440(247084 ILLX UR, via RCA); orInstrumentation Laboratory SpA, Milan,Italy. Tel: 39-2-25221. Tlx: 330112ILSPA I.

Compact printer

Another addition to the wide range ofproducts introduced during the last12 months is now available fromSalter A & D. Weighing 330 g andoperating on either a.c. or batterypower, the unit has been speciallybuilt for use with a wide range ofweighing indicators and electronicand counting balances.

Standard features include: a serialthermal dot matrix printer; a fullrange of statistical functions showingweight and counting data in a num-ber of operations with the addedability to calculate up to 999 datablocks. The AD-8117 is priced at399.00.

Detailsfrom Salter A & D, Spring Road,Smethwick, Warley, West Midlands, UK.Tel.: 021 553 1855.

TLC Autospotter

A comprehensive range ofTLC hard-ware is now available from What-man. The range includes separatingchambers, dipping chambers, UVissystems and features the AutospotterTLC sample application system.

The Autospotter is designed specific-ally for routine quality-control appli-cations and allows the simultaneousapplication and concentration of upto 20 samples on 20 x 20 cm or 20 x10 cm TLC plates. The samplevolume can be varied between 5-501. Spot diameters, after evaporationby the built-in drying system, areheld between mm and 5 mm.

The Autospotter is ideal for use withWhatman Linear-K, pre-channelledand conventional TLC plates.

More information from Whatman Ltd,Springfield Hill, Maidstone, Kent ME142LE, UK. Tel.: 0622 61681.

Chromacol bench-top crimper

Crimpmate (see p. 119) was built toease the work-loads met by growingnumbers of laboratories and otherwork units with increasing vialcrimping requirements.

The main body of the system issupported by a stem on a solid base.It can be raised or lowered to suit thepersonal needs of the user by meansof a simple finger knob. Because ofthe unique leverage system, onlyabout a quarter of the normal musclepressure is used.

The jaws fit into a holder in the mainbody in such a way that they can beinterchanged in 1.ess than 8 seconds.Eachjaw head has a fine tuning knobwhich allows a given jaw head to beadjusted to deal with variations inseal thickness and in vial collartolerances. Four jaw sizes are

presently available: 8 mm, 11 mm, 13mm, 20 mm.

Details from Chromacol Ltd, Glen RossHouse, Summers Row, London N12 OLD,Tel.: 01 368 7666.

Bioscreen

The first of a new generation ofBioscreens has been purchased byUnilever Research and installed attheir Colworth House laboratory inBedfordshire, UK. This latest ver-sion of Labsystems’ microbiologicalgrowth analyser, known as the Bio-screen-C, contains an incubatorwhich is continuously adjustablefrom 15C to 55C.

The instrument purchased by Uni-lever is to be used in a researchproject being run jointly by DrsMartin Cole and Martin Jones of themicrobiology department at Col-worth. The Bioscreen will be utilizedfor predictive modelling of the bac-terial flora associated with a varietyof foodstuffs.

Bioscreen-C is available with a num-ber of different sofware programsdedicated to routine food qualitycontrol, research on anti-microbialcompounds, bioassays and toxicitytesting. As well as aerobic and anae-robic bacteria, Bioscreen may beused for monitoring yeasts andmoulds.

118

New products

range of printers, including the HPLaserJet and HP ThinkJet.

ChemText allows information from a

variety of sources, such as the HPChemStation, to be integrated into a

single document. Images imported toChemText remain computable- thechemist can, for example, move amolecular diagram to and fromChemText documents, data-bases,modelling programs etc. Graphs,chromatograms and other diagramsmay be manipulated and labelled to

produce a complete presentationquality document.

Details from Wendy Holt, Hewlett-Pack-ard Ltd, Miller House, The Ring, Brack-nell, Berkshire RG12 1XN, UK. Tel:0344 424898.

Chromacol Ltd’s Crimplate ’easy action’ bench-top crimper. (See p. 118)

More information from Labsystems (UK)Ltd, 12 Redford Way, Uxbridge, Mid-dlesex UB8 1SZ, UK. Tel.: 0895 38421.

Chemical word-processor

Chemical word-processing is pos-sible on Hewlett-Packard’s Vectrapersonal computer- the user cancreate documents incorporatinggraphical output from data collectedand processed by the HP ChemSta-tion.

The ChemText package, which was

developed by Molecular DesignLimited (California), is designed to

provide an accurate, reliable andeffective means of communicatingchemical information. Reports,documents and scientific papers maybe created easily on the HP Vectra or

equivalent personal computer, andstructures drawn directly on screenusing the mouse.

A word-processor that handles chem-ical symbols, molecular structures,mathematical formulae and otherspecial characters, ChemText out-puts to the printer what is seen onscreen. Text can be produced incor-porating chemical structures, reac-tion diagrams, equations and flow-charts. The software supports a wide

New family coagulation analysers

A new family of three ACETM auto-mated coagulation analysers hasbeen announced by InstrumentationLaboratory (IL). The A CL 100 isdesigned for routine clinical analysisin laboratories running about 30 testsper day. It automates all routineclot-timing analyses, includingsimultaneous analysis ofboth PT andfibrinogen. With 1100 data pointsaveraged into each test result, thesystem offers superior accuracy andprecision. Typical analytical preci-sion within a run is -< 1% coefficientof variation for PT when using ILreagents with fresh plasma.

The A CL 200 performs chromogenicsubstrate assays, in addition to allroutine clot-timing analyses.

The A CL 300 provides all the capabili-ties of the A CL 200 system plushigher throughput, a built-in thermalprinter and an additional RS232Cport. Recommended for larger hospi-tals and research laboratories, it isdesigned to interface with an externalPC computer. A built-in rotorpreheater increases analyticalthroughput from 10 to 175 tests perhour for PT and from 80 to 115 testsper hour for APTT. An optionalResearch Program allows the user tovary test conditions and display for-mats.

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