warrior pda
TRANSCRIPT
new trendsPioneering
Ibn e SinaIbn e Sina was born in 980 C.E. in the village of Afshana near Bukhara.He wrote almost 450 treatises on a wide range of subjects, of which around 240 have survived. In particular, 150 of his surviving treatises concentrate on philosophy and 40 of them concentrate on medicine. Ibn e Sina was one of the pioneers in “ISLAMIC DENTISTRY” and dedicated many chapters of The Canon of Medicine to dentistry, dental
restoration. treatment for dental caries.
new trendsPioneeringSERVAZSERVAZ
250 mgCapsule
( A z i t h r o m y c i n d i h y d r a t e )
SUPERIOR MIC AGAINSTODONTOGENIC PATHOGENS
“Azithromycin (Servaz ) have a Triple role in treatment of Resolution of periodontal Disease.”
Ref: J.Periodontal 1999;70:960:966
TRIPLEROLE IN PERIODONTITIS
Ref: J.Periodontal res. 2012
1: Suppressing Periodontal Pathogens2: Anti Inflammatory activity with Macrophages3: Healing with Fibroblast stimulation
Ref: Data on f ile
Peptostreptococus Spp.
Prevotella Intermedia
Porphyromonas Gingivalis
Actinomyecetecomitans
Strep. Viridians
Strep. Pyogenes
Staph: Aureus
CLINDAMYCIN
0.75 µ/ml
0.12 µ/ml
0.16 µ/ml
4 µ/ml
0.12 µ/ml
0.128 µ/ml
0.38 µ/ml
0 µ/ml
0.5 µ/ml
0.16 µ/ml
1.1 µ/ml
2 µ/ml
1.6 µ/ml
0.94 µ/ml
PATHOGEN AMOXICILLINLINCOMYCIN
4 µ/ml
2 µ/ml
0.6 µ/ml
1.6 µ/ml
4 µ/ml
0.8 µ/ml
0.12 µ/ml
SERVAZ
0.5 µ/ml
0.03 µ/ml
0.02 µ/ml
0.25 µ/ml
0.5 µ/ml
0.1 µ/ml
0.023 µ/ml
(Az i th romyc in )
new trendsPioneeringSERVAZSERVAZ
250 mgCapsule
( A z i t h r o m y c i n d i h y d r a t e )
IDEAL ANTIBIOTIC FORPERIODONTITIS
Ref: Pearly white.Dentition.File.Wordpress.Com/2011/01/azithromycin
“ Azithromycin (SERVAZ) is the latest antibiotic for being trialled for treatment of gum & bone disease (periodontitis). Servaz has remarkable results for the treatment of periodontitis.”
EFFICACIOUS INODONTOSTOMATOLOGICAL
INFECTIONS
SUPERIOR TISSUE CONCENTRATIONS
Ref: Minerva stomatol 1998 jan-feb ; 47 ; (1-2);57-62
“ Azithromycin achieved good therpeutic results in odontostomatological infections in terms of both efficacy & tolerability.”
2.6%
1.1%
(Cefadroxil)
2.12%(Cephalexin)
2.0%(Amoxicillin)
(Clindamycin)
4.0%(Azithromycin)
Ref: Data on f ile
new trendsPioneeringSERVAZSERVAZ
250 mgCapsule
( A z i t h r o m y c i n d i h y d r a t e )
SERVAZIS RECOMMENDED FOR
Peri-Implantitis
Pericoronitis
Periodontitis
Periodontal AbscessDento Alveolar Abscess
Maxillo Facial SurgeryPre & Post Operative Prohylaxis
Gingivitis
Extensive Coverage
Sustained high tissue concentration
Short duration of treatment
Better tolerability
Excellent efficacy in multiple indications
DOSAGESUPERIOR HALF LIFE
1Hr
2-3Hrs
5.4Hrs
14Hrs
Amoxicillin ClindamycinLincomycin Azithromycin
B.D For 1 Day&
1 Cap. O.D for4 days
250mgCapsule
250mgCapsule
B.D For 3 Days
R
Ref 1: Revomet (Metronidazoe), prescribing information, file data; Ref 2: Braz Oral Res 2008;2 2(2):145-50; Ref 3: Revomet (Metronidazoe), prescribing information, file data
How
Works 1
Application
Flowability
Fills thePocket
HighlyViscous
gel
Releaseto formthe gel
Preferred Choice InGingivitis Peridontitis
R.C.T Dry Socket
Root Scaling Stomatitis
R
Concentration in GCF shows its avalaibility till 48 hours 2
Metronidazole is absorbed slowly from the dentalgel and the bioavailability is about 70% 3
% C
once
ntra
tion
in G
CF
Time in Hours
6 Hours 24 Hours 48 Hours
78.57%
39.29%
25%
DENTAL PAIN IS INEVITABLE
SUFFERING IS OPTIONAL
PROVIDES SUPERIOR ANALGESIC ACTIONWITH RAPID RELIEF from...from...
95%Bioavailibility
95%Bioavailibility
QuickAbsorptionQuickAbsorption
Cost EffectiveTherapy
Cost EffectiveTherapy
ConvenientB.D DosageConvenientB.D Dosage
Onset of Action
in 15-min
Onset of Action
in 15-min
PAIN IS INEVITABLESUFFERING IS OPTIONAL
The Striking PowerThe Striking Power
500mgCapsules
“Against the most of Infections InvolvingGram +ve & Gram -ve Bacteria”
Spectrum of Activity:
PATHOGENS ACTIVITY
Porphyromonas gingivalis
Fusobacterium nucleatum
Streptococcus mutans
Streptococcus sanguis
Bacteroides forsythus
Antimicrobial agent and Chemotherapy, Feb 1997. P 324-330
The Striking PowerThe Striking Power
PericoronitisPericoronitisPericoronalAbscessPericoronalAbscess
Pre-PestoperativeProphyalaxis
Pre-PostoperativeProphyalaxis
MaxillofacialSurgery
MaxillofacialSurgery
PulpitisPulpitisBroad spectrum antibiotic
Well tolerated
Better safety profile
Convenient B.D dosage
Cost effective therapy