weekly influenza & respiratory illness activity report

12
Minnesota Department of Health 651-201-5414 or 1-877-676-5414 www.health.state.mn.us Weekly Influenza & Respiratory Illness Activity Report Week Ending Oct. 23, 2021 | WEEK 42 A summary of influenza surveillance indicators prepared by the Division of Infectious Disease Epidemiology Prevention & Control. All data are preliminary and may change as more information is received. Minnesota Influenza Surveillance (www.health.state.mn.us/diseases/flu/stats/) Weekly U.S. Influenza Surveillance Report (www.cdc.gov/flu/weekly/) World Health Organization (WHO) Surveillance (www.who.int/influenza/surveillance_monitoring/updates/en/) Neighboring states’ influenza information: Iowa: Iowa Flu Reports (idph.iowa.gov/influenza/reports) Wisconsin: Influenza (Flu) (www.dhs.wisconsin.gov/communicable/influenza/) North Dakota: Reported Seasonal Influenza Activity in North Dakota (www.ndflu.com/default.aspx) South Dakota: South Dakota Influenza Information (doh.sd.gov/diseases/infectious/flu/) Contents Hospitalized Influenza Surveillance ............................................................................................................2 Influenza-Associated Death Surveillance ...................................................................................................4 Respiratory Disease Outbreak Surveillance: School Outbreaks .................................................................5 Respiratory Disease Outbreak Surveillance: LTC Outbreaks ......................................................................6 Sentinel Provider Surveillance (Outpatients) .............................................................................................7 Laboratory Surveillance ............................................................................................................................. 8 Minnesota Influenza Incidence Surveillance Project (MIISP) ..................................................................10 Weekly U.S. Influenza Surveillance Report ............................................................................................... 12 Minnesota Influenza Key Statistics Percent of molecular laboratory tests positive 0.1% Hospitalizations 2 Most common strain Influenza A and B School outbreaks 17 Long-term care outbreaks 1 Pediatric influenza-associated deaths 0 Due to the COVID-19 pandemic, CDC and MDH will not be posting the weekly geographic spread indicators (no activity, sporadic, local, regional, widespread) this season as they rely on influenza-like illness data (ILI). Because these data are based on symptoms, the cause of ILI cannot reliably be attributed to influenza while COVID-19 is widely circulating.

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Page 1: Weekly Influenza & Respiratory Illness Activity Report

Minnesota Department of Health651-201-5414 or 1-877-676-5414wwwhealthstatemnus

Weekly Influenza amp Respiratory Illness Activity Report

Week Ending Oct 23 2021 | WEEK 42A summary of influenza surveillance indicators prepared by the Division of Infectious Disease Epidemiology Prevention amp Control

All data are preliminary and may change as more information is received

Minnesota Influenza Surveillance (wwwhealthstatemnusdiseasesflustats)Weekly US Influenza Surveillance Report (wwwcdcgovfluweekly) World Health Organization (WHO) Surveillance (wwwwhointinfluenzasurveillance_monitoringupdatesen) Neighboring statesrsquo influenza information Iowa Iowa Flu Reports (idphiowagovinfluenzareports) Wisconsin Influenza (Flu) (wwwdhswisconsingovcommunicableinfluenza) North Dakota Reported Seasonal Influenza Activity in North Dakota (wwwndflucomdefaultaspx) South Dakota South Dakota Influenza Information (dohsdgovdiseasesinfectiousflu)

Contents

Hospitalized Influenza Surveillance 2Influenza-Associated Death Surveillance 4Respiratory Disease Outbreak Surveillance School Outbreaks 5Respiratory Disease Outbreak Surveillance LTC Outbreaks 6Sentinel Provider Surveillance (Outpatients) 7Laboratory Surveillance 8Minnesota Influenza Incidence Surveillance Project (MIISP) 10Weekly US Influenza Surveillance Report 12

Minnesota Influenza Key Statistics

Percent of molecular laboratory tests positive 01

Hospitalizations 2

Most common strain Influenza A and B

School outbreaks 17

Long-term care outbreaks 1

Pediatric influenza-associated deaths 0

Due to the COVID-19 pandemic CDC and MDH will not be posting the weekly geographic spread indicators (no activity sporadic local regional widespread) this season as they rely on influenza-like illness data (ILI) Because these data are based on symptoms the cause of ILI cannot reliably be attributed to influenza while COVID-19 is widely circulating

Week B (no genotype) B (Yamagata) B (Victoria) A (not subtyped) A H3 A H1 (unspecified) A (H1N1)pdm09 A (H1N2v) A (H3N2v) AampB Unknown

1

1

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

3 4 0 3 2 0 1

5 1 4 4 5 1 0

1 2 6 11 6 1 1

3 4 10 8 8 1

4 4 7 5 7 1

4 2 13 7 14 2

3 6 20 2 24 3

2 7 43 7 30 5

2 10 54 10 54 1

3 10 87 13 49 1

8 14 123 9 67 0

9 25 246 18 115 0

11 61 557 51 197 2

8 65 631 52 254 2

10 68 584 55 193 1

11 123 664 51 213 4

20 178 594 100 245 0

32 222 479 139 236 5

48 260 430 132 372 1

98 371 393 159 380 1

162 390 359 228 461 0

213 265 242 197 430 1

263 248 166 260 377 1

191 251 140 234 248 0

105 264 106 193 104 0

119 295 106 189 35 0

59 207 123 140 8 1

59 152 91 92 5 0

37 83 53 51 3 0

19 45 45 56 2 0

13 25 42 28 0 0

7 23 19 28 2 0

6 10 9 11 0 0

0

0

5

10

15

20

25

30

35

40

45

50

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Hos

pita

lizat

ions

MMWR Week

B (no genotype)

B (Yamagata)

B (Victoria)

A (not subtyped)

A H3

A H1 (unspecified)

A (H1N1)pdm09

A (H1N2v)

A (H3N2v)

AampB

Unknown

050

100150200250300350400450500550600650700

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Hos

pita

lizat

ions

MMWR Week

2016-17

2017-18

2018-19

2019-20

2020-21

2021-22

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 2

Hospitalized Influenza Surveillance

Hospitalized influenza cases are based on disease reports of laboratory-positive influenza (via DFA IFA viral culture EIA rapid test paired serological tests or RT-PCR) and specimens from hospitalized patients with acute respiratory illness submitted to MDH-PHL by hospitals and laboratories Due to the need to confirm reports and reporting delays consider current week data preliminary

Hospitalized Influenza Cases by Type Minnesota (FluSurv-NET)

Hospitalizations this week Hospitalizations last week Total hospitalizations (to date)

1 0 2

Hospitalized Influenza Cases by Season Minnesota (FluSurv-NET)

Season Total hospitalizations (historic)

2016-2017 3695

2017-2018 6446

2018-2019 2543

2019-2020 4022

2020-2021 35

2021-2022 2 (to date)FluSurv-NET = Influenza Surveillance Network

Region of hospitalizations Incidence (cases) per 100000 Persons

Central 0 000

Metro 1 003

Northeast 0 000

Northwest 0 000

South Central 0 000

Southeast 0 000

Southwest 1 047

West Central 0 000

Total 2 004

Age of hospitalizations Incidence (cases) per 100000 Persons

0-4 0 000

5-24 0 000

25-49 0 000

50-64 0 000

65+ 2 021

Case Total 2 004

00 00 00 00 00 00

05

0000

10

20

30

40

50

0

5

10

15

20

25

30

35

40

45

50

Cent

ral

Met

ro

Nor

thea

st

Nor

thw

est

Sout

h Ce

ntra

l

Sout

heas

t

Sout

hwes

t

Wes

t Cen

tral

Hospitalizations per 100000 Persons

Num

ber o

f Hos

pita

lizat

ions

Region

of hospitalizations

Incidence (cases) per 100000 Persons

October 3 2021 ndash October 23 2021

00 00 00 00 02

00

10

20

30

40

50

0

5

10

15

20

25

30

35

40

45

50

0-4 5-24 25-49 50-64 65+

Hospitalizations per 100000 Persons

Num

ber o

f Hos

pita

lizat

ions

Age Group (years)

of hospitalizations

Incidence (cases) per 100000 Persons

October 3 2021 ndash October 23 2021

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 3

Hospitalized Influenza Surveillance (continued)Number of Influenza Hospitalizations and Incidence by Region

Minnesota

Median age (years) at time of admission

810

Number of Influenza Hospitalizations and Incidence by Age Minnesota

Region Hospitalizations this week

Total (to date)

Central 0 (0) 0 (0)

Metro 1 (100) 1 (50)

Northeast 0 (0) 0 (0)

Northwest 0 (0) 0 (0)

South Central 0 (0) 0 (0)

Southeast 0 (0) 0 (0)

Southwest 0 (0) 1 (50)

West Central 0 (0) 0 (0)

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

40 0 0 1 0 0 0

41 0 0 0 0 0 0

42 0 0 0 0 0 0

43 0 0 0 1 0

44 0 1 0 0 0

45 0 2 0 0 1

46 0 1 0 1 0

47 1 2 0 0 0

48 0 1 1 1 0

49 2 2 1 1 0

50 2 9 0 3 0

51 1 12 3 2 0

52 1 12 2 3 0

1 2 31 1 8 3

2 2 49 1 10 1

3 7 35 3 4 0

4 6 48 3 5 1

5 7 32 4 8 1

6 16 36 3 7 0

7 26 30 8 9 0

8 28 27 8 13 0

9 21 25 2 21 0

10 22 12 13 16 0

11 28 16 10 15 0

12 24 7 12 11 0

13 13 11 3 5 0

14 19 10 6 4 0

15 16 9 4 3 0

16 12 5 2 0 0

17 6 4 1 0 0

18 4 2 2 1 0

19 4 2 1 1 0

20 0 2 0 0 0

3 0 0

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

0-17 2 6 1 3 0 0

18-49 10 10 9 15 2 0

50-64 20 37 16 31 1 0

65-79 60 101 33 51 1 0

80+ 181 281 36 53 3 0

0

5

10

15

20

25

30

35

40

45

50

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Dea

ths

MMWR Week of Death

2016-17

2017-18

2018-19

2019-20

2020-21

2021-22

0

50

100

150

200

250

300

0-17 18-49 50-64 65-79 80+N

umbe

r of D

eath

sAge Group (years)

2016-17 2017-18 2018-19 2019-20 2020-21 2021-22

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 4

Influenza-Associated Death Surveillance

Influenza deaths are collected via reports from Minnesotarsquos death certificate database hospitals and long-term care facilities Decedents with influenza listed as a cause of or contributor to death have recent laboratory confirmation of influenza or are part of an ongoing influenza outbreak at a long-term care facility are reported to influenza surveillance Due to the need to confirm reports and reporting delays consider current week data preliminary

Deaths Associated with Influenza by Season Minnesota

Deaths Associated with Influenza by Age Group and Season Minnesota

Season Median age (years) at time of death

2016-2017 86

2017-2018 85

2018-2019 75

2019-2020 73

2020-2021 76

2021-2022 ---FluSurv-NET = Influenza Surveillance Network

Season Total deaths (historic) Total pediatric (lt18 years) deaths (historic)

2016-2017 273 2

2017-2018 440 6

2018-2019 126 1

2019-2020 197 3

2020-2021 7 0

2021-2022 0 0

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

40 0 1 1 0 8

41 2 1 3 0 8

42 1 0 1 1 1

43 0 0 4 0

44 2 2 0 0

45 1 4 4 1

46 3 0 7 1

47 2 1 19 0

48 1 1 7 0

49 5 5 14 0

50 19 5 61 0

51 3 6 172 0

52 3 0 5 0

53 5 0 9 0

1 73 12 32 0

2 122 38 121 0

3 77 31 79 0

4 103 8 91 0

5 109 16 79 0

6 66 38 66 0

7 22 30 35 0

8 23 22 44 1

9 4 43 22 0

10 16 33 25 0

11 7 26 2 0

12 3 15 0 0

13 4 12 0 0

14 8 10 0 0

15 8 2 0 0

16 0 5 0 0

17 1 6 0 0

18 3 6 0 0

19 0 4 0 1

20

0

50

100

150

200

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f Inf

luen

za-li

ke Il

lnes

s Out

brea

ks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 61 outbreaks were reported pre-season during weeks 37-39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 5

Respiratory Disease Outbreak Surveillance School Outbreaks

K-12 schools report an outbreak of influenza-like illness (ILI) when the number of students absent with ILI reaches 5 of total enrollment or three or more students with ILI are absent from the same elementary classroom

Influenza-like Illness (ILI) in Schools by Season

New school outbreaks this week New school outbreaks last week Total this season (to date)1 8 17dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

0 0 0 0 0 1

0 0 0 0 0 0

0 0 0 0 0 0

0 0 0 0 0

0 0 0 0 0

1 0 0 2 1

0 1 1 0 0

1 0 0 1 0

0 5 0 1 1

1 3 0 2 0

2 3 0 0 0

1 1 0 2 0

2 18 1 0 0

3 23 0 6 1

3 36 0 6 0

6 24 2 4 0

9 10 2 7 0

11 13 6 9 0

12 13 5 7 0

11 10 3 6 1

21 13 4 19 0

14 8 6 10 1

12 3 5 11 0

11 4 7 8 0

11 9 4 4 0

7 4 3 0 0

10 6 2 0 0

12 1 0 1 0

6 0 2 0 0

7 0 2 0 0

1 1 2 0 0

3 2 1 0

3 0 1 0

2

0

5

10

15

20

25

30

35

40

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f lab

-con

firm

ed o

utbr

eaks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 1 outbreak was reported pre-season during weeks 39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 6

Respiratory Disease Outbreak Surveillance LTC OutbreaksLong-Term Care (LTC) facilities report to MDH when they suspect an outbreak of influenza in their facility Laboratory-confirmed outbreaks are reported here

Confirmed Influenza Outbreaks in LTC by Season

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

New LTC outbreacksI this week New LTCoutbreaks last week Total this season (to date)0 0 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21 2020-21 MN BaselineDagger

40 143 128562 242367 066 13 28

41 143 171591 233836 087 106 28

42 142 139559 221124 073 8800 28

43 124 153928 239513 05 28

44 137 224719 240882 055 28

45 142 175836 227738 07 28

46 164 184595 243498 065 28

47 166 220573 272668 05 28

48 147 208246 405946 042 28

49 215 189865 352987 033 28

50 23 267372 353594 025 28

51 294 258014 565083 014 28

52 364 340117 971059 012 28

53 423 327022 37 024 28

1 506 474847 36 017 28

2 581 321409 33 018 28

3 632 379504 39 028 28

4 646 377994 48 046 28

5 673 325786 54 023 28

6 569 34634 64 03 28

7 533 372245 52 027 28

8 447 33982 54 035 28

9 376 359236 52 027 28

10 298 356018 44 043 28

11 239 303359 36 033 28

12 233 228605 23 035 28

13 166 241452 22 036 28

14 209 22887 16 042 28

15 218 214939 13 042 28

16 165 245684 15 047 28

17 176 215866 16 045 28

18 168 18928 19 043 28

19 14 231566 1 068 28

20

0

2

4

6

8

10

12

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Perc

ent w

ith In

fluen

za-li

ke Il

lnes

s

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Pre-pandemic MN Baselinedagger

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 7

Sentinel Provider Surveillance (Outpatients)

MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to outpatient clinics with influenza-like illness

Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)

of outpatients with ILI this week of outpatients with ILI last week

09 11

Indicates current week-data may be delayed by 1 or more weeks dagger The Week 53 value for these seasons is the average of Week 52 and Week 1Dagger MN Baseline valid for 2020-21 season only do not compare it with previous seasons The baseline is

calculated by averaging the ILI percent for non-influenza weeks over the previous four seasons and adding two standard deviations Non-influenza weeks account for less than 2 of the seasonrsquos total flu-positive specimens tested at Public Health Labs in HHS Region 5 Weeks where ILI is above baseline reflect weeks with excess health care visits due to ILI

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 2: Weekly Influenza & Respiratory Illness Activity Report

Week B (no genotype) B (Yamagata) B (Victoria) A (not subtyped) A H3 A H1 (unspecified) A (H1N1)pdm09 A (H1N2v) A (H3N2v) AampB Unknown

1

1

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

3 4 0 3 2 0 1

5 1 4 4 5 1 0

1 2 6 11 6 1 1

3 4 10 8 8 1

4 4 7 5 7 1

4 2 13 7 14 2

3 6 20 2 24 3

2 7 43 7 30 5

2 10 54 10 54 1

3 10 87 13 49 1

8 14 123 9 67 0

9 25 246 18 115 0

11 61 557 51 197 2

8 65 631 52 254 2

10 68 584 55 193 1

11 123 664 51 213 4

20 178 594 100 245 0

32 222 479 139 236 5

48 260 430 132 372 1

98 371 393 159 380 1

162 390 359 228 461 0

213 265 242 197 430 1

263 248 166 260 377 1

191 251 140 234 248 0

105 264 106 193 104 0

119 295 106 189 35 0

59 207 123 140 8 1

59 152 91 92 5 0

37 83 53 51 3 0

19 45 45 56 2 0

13 25 42 28 0 0

7 23 19 28 2 0

6 10 9 11 0 0

0

0

5

10

15

20

25

30

35

40

45

50

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Hos

pita

lizat

ions

MMWR Week

B (no genotype)

B (Yamagata)

B (Victoria)

A (not subtyped)

A H3

A H1 (unspecified)

A (H1N1)pdm09

A (H1N2v)

A (H3N2v)

AampB

Unknown

050

100150200250300350400450500550600650700

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Hos

pita

lizat

ions

MMWR Week

2016-17

2017-18

2018-19

2019-20

2020-21

2021-22

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 2

Hospitalized Influenza Surveillance

Hospitalized influenza cases are based on disease reports of laboratory-positive influenza (via DFA IFA viral culture EIA rapid test paired serological tests or RT-PCR) and specimens from hospitalized patients with acute respiratory illness submitted to MDH-PHL by hospitals and laboratories Due to the need to confirm reports and reporting delays consider current week data preliminary

Hospitalized Influenza Cases by Type Minnesota (FluSurv-NET)

Hospitalizations this week Hospitalizations last week Total hospitalizations (to date)

1 0 2

Hospitalized Influenza Cases by Season Minnesota (FluSurv-NET)

Season Total hospitalizations (historic)

2016-2017 3695

2017-2018 6446

2018-2019 2543

2019-2020 4022

2020-2021 35

2021-2022 2 (to date)FluSurv-NET = Influenza Surveillance Network

Region of hospitalizations Incidence (cases) per 100000 Persons

Central 0 000

Metro 1 003

Northeast 0 000

Northwest 0 000

South Central 0 000

Southeast 0 000

Southwest 1 047

West Central 0 000

Total 2 004

Age of hospitalizations Incidence (cases) per 100000 Persons

0-4 0 000

5-24 0 000

25-49 0 000

50-64 0 000

65+ 2 021

Case Total 2 004

00 00 00 00 00 00

05

0000

10

20

30

40

50

0

5

10

15

20

25

30

35

40

45

50

Cent

ral

Met

ro

Nor

thea

st

Nor

thw

est

Sout

h Ce

ntra

l

Sout

heas

t

Sout

hwes

t

Wes

t Cen

tral

Hospitalizations per 100000 Persons

Num

ber o

f Hos

pita

lizat

ions

Region

of hospitalizations

Incidence (cases) per 100000 Persons

October 3 2021 ndash October 23 2021

00 00 00 00 02

00

10

20

30

40

50

0

5

10

15

20

25

30

35

40

45

50

0-4 5-24 25-49 50-64 65+

Hospitalizations per 100000 Persons

Num

ber o

f Hos

pita

lizat

ions

Age Group (years)

of hospitalizations

Incidence (cases) per 100000 Persons

October 3 2021 ndash October 23 2021

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 3

Hospitalized Influenza Surveillance (continued)Number of Influenza Hospitalizations and Incidence by Region

Minnesota

Median age (years) at time of admission

810

Number of Influenza Hospitalizations and Incidence by Age Minnesota

Region Hospitalizations this week

Total (to date)

Central 0 (0) 0 (0)

Metro 1 (100) 1 (50)

Northeast 0 (0) 0 (0)

Northwest 0 (0) 0 (0)

South Central 0 (0) 0 (0)

Southeast 0 (0) 0 (0)

Southwest 0 (0) 1 (50)

West Central 0 (0) 0 (0)

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

40 0 0 1 0 0 0

41 0 0 0 0 0 0

42 0 0 0 0 0 0

43 0 0 0 1 0

44 0 1 0 0 0

45 0 2 0 0 1

46 0 1 0 1 0

47 1 2 0 0 0

48 0 1 1 1 0

49 2 2 1 1 0

50 2 9 0 3 0

51 1 12 3 2 0

52 1 12 2 3 0

1 2 31 1 8 3

2 2 49 1 10 1

3 7 35 3 4 0

4 6 48 3 5 1

5 7 32 4 8 1

6 16 36 3 7 0

7 26 30 8 9 0

8 28 27 8 13 0

9 21 25 2 21 0

10 22 12 13 16 0

11 28 16 10 15 0

12 24 7 12 11 0

13 13 11 3 5 0

14 19 10 6 4 0

15 16 9 4 3 0

16 12 5 2 0 0

17 6 4 1 0 0

18 4 2 2 1 0

19 4 2 1 1 0

20 0 2 0 0 0

3 0 0

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

0-17 2 6 1 3 0 0

18-49 10 10 9 15 2 0

50-64 20 37 16 31 1 0

65-79 60 101 33 51 1 0

80+ 181 281 36 53 3 0

0

5

10

15

20

25

30

35

40

45

50

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Dea

ths

MMWR Week of Death

2016-17

2017-18

2018-19

2019-20

2020-21

2021-22

0

50

100

150

200

250

300

0-17 18-49 50-64 65-79 80+N

umbe

r of D

eath

sAge Group (years)

2016-17 2017-18 2018-19 2019-20 2020-21 2021-22

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 4

Influenza-Associated Death Surveillance

Influenza deaths are collected via reports from Minnesotarsquos death certificate database hospitals and long-term care facilities Decedents with influenza listed as a cause of or contributor to death have recent laboratory confirmation of influenza or are part of an ongoing influenza outbreak at a long-term care facility are reported to influenza surveillance Due to the need to confirm reports and reporting delays consider current week data preliminary

Deaths Associated with Influenza by Season Minnesota

Deaths Associated with Influenza by Age Group and Season Minnesota

Season Median age (years) at time of death

2016-2017 86

2017-2018 85

2018-2019 75

2019-2020 73

2020-2021 76

2021-2022 ---FluSurv-NET = Influenza Surveillance Network

Season Total deaths (historic) Total pediatric (lt18 years) deaths (historic)

2016-2017 273 2

2017-2018 440 6

2018-2019 126 1

2019-2020 197 3

2020-2021 7 0

2021-2022 0 0

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

40 0 1 1 0 8

41 2 1 3 0 8

42 1 0 1 1 1

43 0 0 4 0

44 2 2 0 0

45 1 4 4 1

46 3 0 7 1

47 2 1 19 0

48 1 1 7 0

49 5 5 14 0

50 19 5 61 0

51 3 6 172 0

52 3 0 5 0

53 5 0 9 0

1 73 12 32 0

2 122 38 121 0

3 77 31 79 0

4 103 8 91 0

5 109 16 79 0

6 66 38 66 0

7 22 30 35 0

8 23 22 44 1

9 4 43 22 0

10 16 33 25 0

11 7 26 2 0

12 3 15 0 0

13 4 12 0 0

14 8 10 0 0

15 8 2 0 0

16 0 5 0 0

17 1 6 0 0

18 3 6 0 0

19 0 4 0 1

20

0

50

100

150

200

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f Inf

luen

za-li

ke Il

lnes

s Out

brea

ks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 61 outbreaks were reported pre-season during weeks 37-39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 5

Respiratory Disease Outbreak Surveillance School Outbreaks

K-12 schools report an outbreak of influenza-like illness (ILI) when the number of students absent with ILI reaches 5 of total enrollment or three or more students with ILI are absent from the same elementary classroom

Influenza-like Illness (ILI) in Schools by Season

New school outbreaks this week New school outbreaks last week Total this season (to date)1 8 17dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

0 0 0 0 0 1

0 0 0 0 0 0

0 0 0 0 0 0

0 0 0 0 0

0 0 0 0 0

1 0 0 2 1

0 1 1 0 0

1 0 0 1 0

0 5 0 1 1

1 3 0 2 0

2 3 0 0 0

1 1 0 2 0

2 18 1 0 0

3 23 0 6 1

3 36 0 6 0

6 24 2 4 0

9 10 2 7 0

11 13 6 9 0

12 13 5 7 0

11 10 3 6 1

21 13 4 19 0

14 8 6 10 1

12 3 5 11 0

11 4 7 8 0

11 9 4 4 0

7 4 3 0 0

10 6 2 0 0

12 1 0 1 0

6 0 2 0 0

7 0 2 0 0

1 1 2 0 0

3 2 1 0

3 0 1 0

2

0

5

10

15

20

25

30

35

40

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f lab

-con

firm

ed o

utbr

eaks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 1 outbreak was reported pre-season during weeks 39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 6

Respiratory Disease Outbreak Surveillance LTC OutbreaksLong-Term Care (LTC) facilities report to MDH when they suspect an outbreak of influenza in their facility Laboratory-confirmed outbreaks are reported here

Confirmed Influenza Outbreaks in LTC by Season

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

New LTC outbreacksI this week New LTCoutbreaks last week Total this season (to date)0 0 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21 2020-21 MN BaselineDagger

40 143 128562 242367 066 13 28

41 143 171591 233836 087 106 28

42 142 139559 221124 073 8800 28

43 124 153928 239513 05 28

44 137 224719 240882 055 28

45 142 175836 227738 07 28

46 164 184595 243498 065 28

47 166 220573 272668 05 28

48 147 208246 405946 042 28

49 215 189865 352987 033 28

50 23 267372 353594 025 28

51 294 258014 565083 014 28

52 364 340117 971059 012 28

53 423 327022 37 024 28

1 506 474847 36 017 28

2 581 321409 33 018 28

3 632 379504 39 028 28

4 646 377994 48 046 28

5 673 325786 54 023 28

6 569 34634 64 03 28

7 533 372245 52 027 28

8 447 33982 54 035 28

9 376 359236 52 027 28

10 298 356018 44 043 28

11 239 303359 36 033 28

12 233 228605 23 035 28

13 166 241452 22 036 28

14 209 22887 16 042 28

15 218 214939 13 042 28

16 165 245684 15 047 28

17 176 215866 16 045 28

18 168 18928 19 043 28

19 14 231566 1 068 28

20

0

2

4

6

8

10

12

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Perc

ent w

ith In

fluen

za-li

ke Il

lnes

s

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Pre-pandemic MN Baselinedagger

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 7

Sentinel Provider Surveillance (Outpatients)

MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to outpatient clinics with influenza-like illness

Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)

of outpatients with ILI this week of outpatients with ILI last week

09 11

Indicates current week-data may be delayed by 1 or more weeks dagger The Week 53 value for these seasons is the average of Week 52 and Week 1Dagger MN Baseline valid for 2020-21 season only do not compare it with previous seasons The baseline is

calculated by averaging the ILI percent for non-influenza weeks over the previous four seasons and adding two standard deviations Non-influenza weeks account for less than 2 of the seasonrsquos total flu-positive specimens tested at Public Health Labs in HHS Region 5 Weeks where ILI is above baseline reflect weeks with excess health care visits due to ILI

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 3: Weekly Influenza & Respiratory Illness Activity Report

Region of hospitalizations Incidence (cases) per 100000 Persons

Central 0 000

Metro 1 003

Northeast 0 000

Northwest 0 000

South Central 0 000

Southeast 0 000

Southwest 1 047

West Central 0 000

Total 2 004

Age of hospitalizations Incidence (cases) per 100000 Persons

0-4 0 000

5-24 0 000

25-49 0 000

50-64 0 000

65+ 2 021

Case Total 2 004

00 00 00 00 00 00

05

0000

10

20

30

40

50

0

5

10

15

20

25

30

35

40

45

50

Cent

ral

Met

ro

Nor

thea

st

Nor

thw

est

Sout

h Ce

ntra

l

Sout

heas

t

Sout

hwes

t

Wes

t Cen

tral

Hospitalizations per 100000 Persons

Num

ber o

f Hos

pita

lizat

ions

Region

of hospitalizations

Incidence (cases) per 100000 Persons

October 3 2021 ndash October 23 2021

00 00 00 00 02

00

10

20

30

40

50

0

5

10

15

20

25

30

35

40

45

50

0-4 5-24 25-49 50-64 65+

Hospitalizations per 100000 Persons

Num

ber o

f Hos

pita

lizat

ions

Age Group (years)

of hospitalizations

Incidence (cases) per 100000 Persons

October 3 2021 ndash October 23 2021

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 3

Hospitalized Influenza Surveillance (continued)Number of Influenza Hospitalizations and Incidence by Region

Minnesota

Median age (years) at time of admission

810

Number of Influenza Hospitalizations and Incidence by Age Minnesota

Region Hospitalizations this week

Total (to date)

Central 0 (0) 0 (0)

Metro 1 (100) 1 (50)

Northeast 0 (0) 0 (0)

Northwest 0 (0) 0 (0)

South Central 0 (0) 0 (0)

Southeast 0 (0) 0 (0)

Southwest 0 (0) 1 (50)

West Central 0 (0) 0 (0)

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

40 0 0 1 0 0 0

41 0 0 0 0 0 0

42 0 0 0 0 0 0

43 0 0 0 1 0

44 0 1 0 0 0

45 0 2 0 0 1

46 0 1 0 1 0

47 1 2 0 0 0

48 0 1 1 1 0

49 2 2 1 1 0

50 2 9 0 3 0

51 1 12 3 2 0

52 1 12 2 3 0

1 2 31 1 8 3

2 2 49 1 10 1

3 7 35 3 4 0

4 6 48 3 5 1

5 7 32 4 8 1

6 16 36 3 7 0

7 26 30 8 9 0

8 28 27 8 13 0

9 21 25 2 21 0

10 22 12 13 16 0

11 28 16 10 15 0

12 24 7 12 11 0

13 13 11 3 5 0

14 19 10 6 4 0

15 16 9 4 3 0

16 12 5 2 0 0

17 6 4 1 0 0

18 4 2 2 1 0

19 4 2 1 1 0

20 0 2 0 0 0

3 0 0

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

0-17 2 6 1 3 0 0

18-49 10 10 9 15 2 0

50-64 20 37 16 31 1 0

65-79 60 101 33 51 1 0

80+ 181 281 36 53 3 0

0

5

10

15

20

25

30

35

40

45

50

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Dea

ths

MMWR Week of Death

2016-17

2017-18

2018-19

2019-20

2020-21

2021-22

0

50

100

150

200

250

300

0-17 18-49 50-64 65-79 80+N

umbe

r of D

eath

sAge Group (years)

2016-17 2017-18 2018-19 2019-20 2020-21 2021-22

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 4

Influenza-Associated Death Surveillance

Influenza deaths are collected via reports from Minnesotarsquos death certificate database hospitals and long-term care facilities Decedents with influenza listed as a cause of or contributor to death have recent laboratory confirmation of influenza or are part of an ongoing influenza outbreak at a long-term care facility are reported to influenza surveillance Due to the need to confirm reports and reporting delays consider current week data preliminary

Deaths Associated with Influenza by Season Minnesota

Deaths Associated with Influenza by Age Group and Season Minnesota

Season Median age (years) at time of death

2016-2017 86

2017-2018 85

2018-2019 75

2019-2020 73

2020-2021 76

2021-2022 ---FluSurv-NET = Influenza Surveillance Network

Season Total deaths (historic) Total pediatric (lt18 years) deaths (historic)

2016-2017 273 2

2017-2018 440 6

2018-2019 126 1

2019-2020 197 3

2020-2021 7 0

2021-2022 0 0

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

40 0 1 1 0 8

41 2 1 3 0 8

42 1 0 1 1 1

43 0 0 4 0

44 2 2 0 0

45 1 4 4 1

46 3 0 7 1

47 2 1 19 0

48 1 1 7 0

49 5 5 14 0

50 19 5 61 0

51 3 6 172 0

52 3 0 5 0

53 5 0 9 0

1 73 12 32 0

2 122 38 121 0

3 77 31 79 0

4 103 8 91 0

5 109 16 79 0

6 66 38 66 0

7 22 30 35 0

8 23 22 44 1

9 4 43 22 0

10 16 33 25 0

11 7 26 2 0

12 3 15 0 0

13 4 12 0 0

14 8 10 0 0

15 8 2 0 0

16 0 5 0 0

17 1 6 0 0

18 3 6 0 0

19 0 4 0 1

20

0

50

100

150

200

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f Inf

luen

za-li

ke Il

lnes

s Out

brea

ks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 61 outbreaks were reported pre-season during weeks 37-39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 5

Respiratory Disease Outbreak Surveillance School Outbreaks

K-12 schools report an outbreak of influenza-like illness (ILI) when the number of students absent with ILI reaches 5 of total enrollment or three or more students with ILI are absent from the same elementary classroom

Influenza-like Illness (ILI) in Schools by Season

New school outbreaks this week New school outbreaks last week Total this season (to date)1 8 17dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

0 0 0 0 0 1

0 0 0 0 0 0

0 0 0 0 0 0

0 0 0 0 0

0 0 0 0 0

1 0 0 2 1

0 1 1 0 0

1 0 0 1 0

0 5 0 1 1

1 3 0 2 0

2 3 0 0 0

1 1 0 2 0

2 18 1 0 0

3 23 0 6 1

3 36 0 6 0

6 24 2 4 0

9 10 2 7 0

11 13 6 9 0

12 13 5 7 0

11 10 3 6 1

21 13 4 19 0

14 8 6 10 1

12 3 5 11 0

11 4 7 8 0

11 9 4 4 0

7 4 3 0 0

10 6 2 0 0

12 1 0 1 0

6 0 2 0 0

7 0 2 0 0

1 1 2 0 0

3 2 1 0

3 0 1 0

2

0

5

10

15

20

25

30

35

40

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f lab

-con

firm

ed o

utbr

eaks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 1 outbreak was reported pre-season during weeks 39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 6

Respiratory Disease Outbreak Surveillance LTC OutbreaksLong-Term Care (LTC) facilities report to MDH when they suspect an outbreak of influenza in their facility Laboratory-confirmed outbreaks are reported here

Confirmed Influenza Outbreaks in LTC by Season

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

New LTC outbreacksI this week New LTCoutbreaks last week Total this season (to date)0 0 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21 2020-21 MN BaselineDagger

40 143 128562 242367 066 13 28

41 143 171591 233836 087 106 28

42 142 139559 221124 073 8800 28

43 124 153928 239513 05 28

44 137 224719 240882 055 28

45 142 175836 227738 07 28

46 164 184595 243498 065 28

47 166 220573 272668 05 28

48 147 208246 405946 042 28

49 215 189865 352987 033 28

50 23 267372 353594 025 28

51 294 258014 565083 014 28

52 364 340117 971059 012 28

53 423 327022 37 024 28

1 506 474847 36 017 28

2 581 321409 33 018 28

3 632 379504 39 028 28

4 646 377994 48 046 28

5 673 325786 54 023 28

6 569 34634 64 03 28

7 533 372245 52 027 28

8 447 33982 54 035 28

9 376 359236 52 027 28

10 298 356018 44 043 28

11 239 303359 36 033 28

12 233 228605 23 035 28

13 166 241452 22 036 28

14 209 22887 16 042 28

15 218 214939 13 042 28

16 165 245684 15 047 28

17 176 215866 16 045 28

18 168 18928 19 043 28

19 14 231566 1 068 28

20

0

2

4

6

8

10

12

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Perc

ent w

ith In

fluen

za-li

ke Il

lnes

s

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Pre-pandemic MN Baselinedagger

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 7

Sentinel Provider Surveillance (Outpatients)

MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to outpatient clinics with influenza-like illness

Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)

of outpatients with ILI this week of outpatients with ILI last week

09 11

Indicates current week-data may be delayed by 1 or more weeks dagger The Week 53 value for these seasons is the average of Week 52 and Week 1Dagger MN Baseline valid for 2020-21 season only do not compare it with previous seasons The baseline is

calculated by averaging the ILI percent for non-influenza weeks over the previous four seasons and adding two standard deviations Non-influenza weeks account for less than 2 of the seasonrsquos total flu-positive specimens tested at Public Health Labs in HHS Region 5 Weeks where ILI is above baseline reflect weeks with excess health care visits due to ILI

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 4: Weekly Influenza & Respiratory Illness Activity Report

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

40 0 0 1 0 0 0

41 0 0 0 0 0 0

42 0 0 0 0 0 0

43 0 0 0 1 0

44 0 1 0 0 0

45 0 2 0 0 1

46 0 1 0 1 0

47 1 2 0 0 0

48 0 1 1 1 0

49 2 2 1 1 0

50 2 9 0 3 0

51 1 12 3 2 0

52 1 12 2 3 0

1 2 31 1 8 3

2 2 49 1 10 1

3 7 35 3 4 0

4 6 48 3 5 1

5 7 32 4 8 1

6 16 36 3 7 0

7 26 30 8 9 0

8 28 27 8 13 0

9 21 25 2 21 0

10 22 12 13 16 0

11 28 16 10 15 0

12 24 7 12 11 0

13 13 11 3 5 0

14 19 10 6 4 0

15 16 9 4 3 0

16 12 5 2 0 0

17 6 4 1 0 0

18 4 2 2 1 0

19 4 2 1 1 0

20 0 2 0 0 0

3 0 0

Week 2015-16 2016-17 2017-18 2018-19 2019-20 2020-21

0-17 2 6 1 3 0 0

18-49 10 10 9 15 2 0

50-64 20 37 16 31 1 0

65-79 60 101 33 51 1 0

80+ 181 281 36 53 3 0

0

5

10

15

20

25

30

35

40

45

50

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Num

ber o

f Dea

ths

MMWR Week of Death

2016-17

2017-18

2018-19

2019-20

2020-21

2021-22

0

50

100

150

200

250

300

0-17 18-49 50-64 65-79 80+N

umbe

r of D

eath

sAge Group (years)

2016-17 2017-18 2018-19 2019-20 2020-21 2021-22

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 4

Influenza-Associated Death Surveillance

Influenza deaths are collected via reports from Minnesotarsquos death certificate database hospitals and long-term care facilities Decedents with influenza listed as a cause of or contributor to death have recent laboratory confirmation of influenza or are part of an ongoing influenza outbreak at a long-term care facility are reported to influenza surveillance Due to the need to confirm reports and reporting delays consider current week data preliminary

Deaths Associated with Influenza by Season Minnesota

Deaths Associated with Influenza by Age Group and Season Minnesota

Season Median age (years) at time of death

2016-2017 86

2017-2018 85

2018-2019 75

2019-2020 73

2020-2021 76

2021-2022 ---FluSurv-NET = Influenza Surveillance Network

Season Total deaths (historic) Total pediatric (lt18 years) deaths (historic)

2016-2017 273 2

2017-2018 440 6

2018-2019 126 1

2019-2020 197 3

2020-2021 7 0

2021-2022 0 0

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

40 0 1 1 0 8

41 2 1 3 0 8

42 1 0 1 1 1

43 0 0 4 0

44 2 2 0 0

45 1 4 4 1

46 3 0 7 1

47 2 1 19 0

48 1 1 7 0

49 5 5 14 0

50 19 5 61 0

51 3 6 172 0

52 3 0 5 0

53 5 0 9 0

1 73 12 32 0

2 122 38 121 0

3 77 31 79 0

4 103 8 91 0

5 109 16 79 0

6 66 38 66 0

7 22 30 35 0

8 23 22 44 1

9 4 43 22 0

10 16 33 25 0

11 7 26 2 0

12 3 15 0 0

13 4 12 0 0

14 8 10 0 0

15 8 2 0 0

16 0 5 0 0

17 1 6 0 0

18 3 6 0 0

19 0 4 0 1

20

0

50

100

150

200

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f Inf

luen

za-li

ke Il

lnes

s Out

brea

ks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 61 outbreaks were reported pre-season during weeks 37-39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 5

Respiratory Disease Outbreak Surveillance School Outbreaks

K-12 schools report an outbreak of influenza-like illness (ILI) when the number of students absent with ILI reaches 5 of total enrollment or three or more students with ILI are absent from the same elementary classroom

Influenza-like Illness (ILI) in Schools by Season

New school outbreaks this week New school outbreaks last week Total this season (to date)1 8 17dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

0 0 0 0 0 1

0 0 0 0 0 0

0 0 0 0 0 0

0 0 0 0 0

0 0 0 0 0

1 0 0 2 1

0 1 1 0 0

1 0 0 1 0

0 5 0 1 1

1 3 0 2 0

2 3 0 0 0

1 1 0 2 0

2 18 1 0 0

3 23 0 6 1

3 36 0 6 0

6 24 2 4 0

9 10 2 7 0

11 13 6 9 0

12 13 5 7 0

11 10 3 6 1

21 13 4 19 0

14 8 6 10 1

12 3 5 11 0

11 4 7 8 0

11 9 4 4 0

7 4 3 0 0

10 6 2 0 0

12 1 0 1 0

6 0 2 0 0

7 0 2 0 0

1 1 2 0 0

3 2 1 0

3 0 1 0

2

0

5

10

15

20

25

30

35

40

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f lab

-con

firm

ed o

utbr

eaks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 1 outbreak was reported pre-season during weeks 39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 6

Respiratory Disease Outbreak Surveillance LTC OutbreaksLong-Term Care (LTC) facilities report to MDH when they suspect an outbreak of influenza in their facility Laboratory-confirmed outbreaks are reported here

Confirmed Influenza Outbreaks in LTC by Season

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

New LTC outbreacksI this week New LTCoutbreaks last week Total this season (to date)0 0 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21 2020-21 MN BaselineDagger

40 143 128562 242367 066 13 28

41 143 171591 233836 087 106 28

42 142 139559 221124 073 8800 28

43 124 153928 239513 05 28

44 137 224719 240882 055 28

45 142 175836 227738 07 28

46 164 184595 243498 065 28

47 166 220573 272668 05 28

48 147 208246 405946 042 28

49 215 189865 352987 033 28

50 23 267372 353594 025 28

51 294 258014 565083 014 28

52 364 340117 971059 012 28

53 423 327022 37 024 28

1 506 474847 36 017 28

2 581 321409 33 018 28

3 632 379504 39 028 28

4 646 377994 48 046 28

5 673 325786 54 023 28

6 569 34634 64 03 28

7 533 372245 52 027 28

8 447 33982 54 035 28

9 376 359236 52 027 28

10 298 356018 44 043 28

11 239 303359 36 033 28

12 233 228605 23 035 28

13 166 241452 22 036 28

14 209 22887 16 042 28

15 218 214939 13 042 28

16 165 245684 15 047 28

17 176 215866 16 045 28

18 168 18928 19 043 28

19 14 231566 1 068 28

20

0

2

4

6

8

10

12

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Perc

ent w

ith In

fluen

za-li

ke Il

lnes

s

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Pre-pandemic MN Baselinedagger

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 7

Sentinel Provider Surveillance (Outpatients)

MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to outpatient clinics with influenza-like illness

Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)

of outpatients with ILI this week of outpatients with ILI last week

09 11

Indicates current week-data may be delayed by 1 or more weeks dagger The Week 53 value for these seasons is the average of Week 52 and Week 1Dagger MN Baseline valid for 2020-21 season only do not compare it with previous seasons The baseline is

calculated by averaging the ILI percent for non-influenza weeks over the previous four seasons and adding two standard deviations Non-influenza weeks account for less than 2 of the seasonrsquos total flu-positive specimens tested at Public Health Labs in HHS Region 5 Weeks where ILI is above baseline reflect weeks with excess health care visits due to ILI

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 5: Weekly Influenza & Respiratory Illness Activity Report

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

40 0 1 1 0 8

41 2 1 3 0 8

42 1 0 1 1 1

43 0 0 4 0

44 2 2 0 0

45 1 4 4 1

46 3 0 7 1

47 2 1 19 0

48 1 1 7 0

49 5 5 14 0

50 19 5 61 0

51 3 6 172 0

52 3 0 5 0

53 5 0 9 0

1 73 12 32 0

2 122 38 121 0

3 77 31 79 0

4 103 8 91 0

5 109 16 79 0

6 66 38 66 0

7 22 30 35 0

8 23 22 44 1

9 4 43 22 0

10 16 33 25 0

11 7 26 2 0

12 3 15 0 0

13 4 12 0 0

14 8 10 0 0

15 8 2 0 0

16 0 5 0 0

17 1 6 0 0

18 3 6 0 0

19 0 4 0 1

20

0

50

100

150

200

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f Inf

luen

za-li

ke Il

lnes

s Out

brea

ks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 61 outbreaks were reported pre-season during weeks 37-39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 5

Respiratory Disease Outbreak Surveillance School Outbreaks

K-12 schools report an outbreak of influenza-like illness (ILI) when the number of students absent with ILI reaches 5 of total enrollment or three or more students with ILI are absent from the same elementary classroom

Influenza-like Illness (ILI) in Schools by Season

New school outbreaks this week New school outbreaks last week Total this season (to date)1 8 17dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

0 0 0 0 0 1

0 0 0 0 0 0

0 0 0 0 0 0

0 0 0 0 0

0 0 0 0 0

1 0 0 2 1

0 1 1 0 0

1 0 0 1 0

0 5 0 1 1

1 3 0 2 0

2 3 0 0 0

1 1 0 2 0

2 18 1 0 0

3 23 0 6 1

3 36 0 6 0

6 24 2 4 0

9 10 2 7 0

11 13 6 9 0

12 13 5 7 0

11 10 3 6 1

21 13 4 19 0

14 8 6 10 1

12 3 5 11 0

11 4 7 8 0

11 9 4 4 0

7 4 3 0 0

10 6 2 0 0

12 1 0 1 0

6 0 2 0 0

7 0 2 0 0

1 1 2 0 0

3 2 1 0

3 0 1 0

2

0

5

10

15

20

25

30

35

40

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f lab

-con

firm

ed o

utbr

eaks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 1 outbreak was reported pre-season during weeks 39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 6

Respiratory Disease Outbreak Surveillance LTC OutbreaksLong-Term Care (LTC) facilities report to MDH when they suspect an outbreak of influenza in their facility Laboratory-confirmed outbreaks are reported here

Confirmed Influenza Outbreaks in LTC by Season

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

New LTC outbreacksI this week New LTCoutbreaks last week Total this season (to date)0 0 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21 2020-21 MN BaselineDagger

40 143 128562 242367 066 13 28

41 143 171591 233836 087 106 28

42 142 139559 221124 073 8800 28

43 124 153928 239513 05 28

44 137 224719 240882 055 28

45 142 175836 227738 07 28

46 164 184595 243498 065 28

47 166 220573 272668 05 28

48 147 208246 405946 042 28

49 215 189865 352987 033 28

50 23 267372 353594 025 28

51 294 258014 565083 014 28

52 364 340117 971059 012 28

53 423 327022 37 024 28

1 506 474847 36 017 28

2 581 321409 33 018 28

3 632 379504 39 028 28

4 646 377994 48 046 28

5 673 325786 54 023 28

6 569 34634 64 03 28

7 533 372245 52 027 28

8 447 33982 54 035 28

9 376 359236 52 027 28

10 298 356018 44 043 28

11 239 303359 36 033 28

12 233 228605 23 035 28

13 166 241452 22 036 28

14 209 22887 16 042 28

15 218 214939 13 042 28

16 165 245684 15 047 28

17 176 215866 16 045 28

18 168 18928 19 043 28

19 14 231566 1 068 28

20

0

2

4

6

8

10

12

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Perc

ent w

ith In

fluen

za-li

ke Il

lnes

s

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Pre-pandemic MN Baselinedagger

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 7

Sentinel Provider Surveillance (Outpatients)

MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to outpatient clinics with influenza-like illness

Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)

of outpatients with ILI this week of outpatients with ILI last week

09 11

Indicates current week-data may be delayed by 1 or more weeks dagger The Week 53 value for these seasons is the average of Week 52 and Week 1Dagger MN Baseline valid for 2020-21 season only do not compare it with previous seasons The baseline is

calculated by averaging the ILI percent for non-influenza weeks over the previous four seasons and adding two standard deviations Non-influenza weeks account for less than 2 of the seasonrsquos total flu-positive specimens tested at Public Health Labs in HHS Region 5 Weeks where ILI is above baseline reflect weeks with excess health care visits due to ILI

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 6: Weekly Influenza & Respiratory Illness Activity Report

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21

0 0 0 0 0 1

0 0 0 0 0 0

0 0 0 0 0 0

0 0 0 0 0

0 0 0 0 0

1 0 0 2 1

0 1 1 0 0

1 0 0 1 0

0 5 0 1 1

1 3 0 2 0

2 3 0 0 0

1 1 0 2 0

2 18 1 0 0

3 23 0 6 1

3 36 0 6 0

6 24 2 4 0

9 10 2 7 0

11 13 6 9 0

12 13 5 7 0

11 10 3 6 1

21 13 4 19 0

14 8 6 10 1

12 3 5 11 0

11 4 7 8 0

11 9 4 4 0

7 4 3 0 0

10 6 2 0 0

12 1 0 1 0

6 0 2 0 0

7 0 2 0 0

1 1 2 0 0

3 2 1 0

3 0 1 0

2

0

5

10

15

20

25

30

35

40

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber o

f lab

-con

firm

ed o

utbr

eaks

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Current week

Note 1 outbreak was reported pre-season during weeks 39

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 6

Respiratory Disease Outbreak Surveillance LTC OutbreaksLong-Term Care (LTC) facilities report to MDH when they suspect an outbreak of influenza in their facility Laboratory-confirmed outbreaks are reported here

Confirmed Influenza Outbreaks in LTC by Season

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

New LTC outbreacksI this week New LTCoutbreaks last week Total this season (to date)0 0 1

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21 2020-21 MN BaselineDagger

40 143 128562 242367 066 13 28

41 143 171591 233836 087 106 28

42 142 139559 221124 073 8800 28

43 124 153928 239513 05 28

44 137 224719 240882 055 28

45 142 175836 227738 07 28

46 164 184595 243498 065 28

47 166 220573 272668 05 28

48 147 208246 405946 042 28

49 215 189865 352987 033 28

50 23 267372 353594 025 28

51 294 258014 565083 014 28

52 364 340117 971059 012 28

53 423 327022 37 024 28

1 506 474847 36 017 28

2 581 321409 33 018 28

3 632 379504 39 028 28

4 646 377994 48 046 28

5 673 325786 54 023 28

6 569 34634 64 03 28

7 533 372245 52 027 28

8 447 33982 54 035 28

9 376 359236 52 027 28

10 298 356018 44 043 28

11 239 303359 36 033 28

12 233 228605 23 035 28

13 166 241452 22 036 28

14 209 22887 16 042 28

15 218 214939 13 042 28

16 165 245684 15 047 28

17 176 215866 16 045 28

18 168 18928 19 043 28

19 14 231566 1 068 28

20

0

2

4

6

8

10

12

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Perc

ent w

ith In

fluen

za-li

ke Il

lnes

s

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Pre-pandemic MN Baselinedagger

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 7

Sentinel Provider Surveillance (Outpatients)

MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to outpatient clinics with influenza-like illness

Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)

of outpatients with ILI this week of outpatients with ILI last week

09 11

Indicates current week-data may be delayed by 1 or more weeks dagger The Week 53 value for these seasons is the average of Week 52 and Week 1Dagger MN Baseline valid for 2020-21 season only do not compare it with previous seasons The baseline is

calculated by averaging the ILI percent for non-influenza weeks over the previous four seasons and adding two standard deviations Non-influenza weeks account for less than 2 of the seasonrsquos total flu-positive specimens tested at Public Health Labs in HHS Region 5 Weeks where ILI is above baseline reflect weeks with excess health care visits due to ILI

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 7: Weekly Influenza & Respiratory Illness Activity Report

Week 2016-17dagger 2017-18dagger 2018-19dagger 2019-20dagger 2020-21 2020-21 MN BaselineDagger

40 143 128562 242367 066 13 28

41 143 171591 233836 087 106 28

42 142 139559 221124 073 8800 28

43 124 153928 239513 05 28

44 137 224719 240882 055 28

45 142 175836 227738 07 28

46 164 184595 243498 065 28

47 166 220573 272668 05 28

48 147 208246 405946 042 28

49 215 189865 352987 033 28

50 23 267372 353594 025 28

51 294 258014 565083 014 28

52 364 340117 971059 012 28

53 423 327022 37 024 28

1 506 474847 36 017 28

2 581 321409 33 018 28

3 632 379504 39 028 28

4 646 377994 48 046 28

5 673 325786 54 023 28

6 569 34634 64 03 28

7 533 372245 52 027 28

8 447 33982 54 035 28

9 376 359236 52 027 28

10 298 356018 44 043 28

11 239 303359 36 033 28

12 233 228605 23 035 28

13 166 241452 22 036 28

14 209 22887 16 042 28

15 218 214939 13 042 28

16 165 245684 15 047 28

17 176 215866 16 045 28

18 168 18928 19 043 28

19 14 231566 1 068 28

20

0

2

4

6

8

10

12

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Perc

ent w

ith In

fluen

za-li

ke Il

lnes

s

MMWR Week

2017-18

2018-19

2019-20

2020-21

2021-22

Pre-pandemic MN Baselinedagger

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 7

Sentinel Provider Surveillance (Outpatients)

MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to outpatient clinics with influenza-like illness

Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)

of outpatients with ILI this week of outpatients with ILI last week

09 11

Indicates current week-data may be delayed by 1 or more weeks dagger The Week 53 value for these seasons is the average of Week 52 and Week 1Dagger MN Baseline valid for 2020-21 season only do not compare it with previous seasons The baseline is

calculated by averaging the ILI percent for non-influenza weeks over the previous four seasons and adding two standard deviations Non-influenza weeks account for less than 2 of the seasonrsquos total flu-positive specimens tested at Public Health Labs in HHS Region 5 Weeks where ILI is above baseline reflect weeks with excess health care visits due to ILI

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 8: Weekly Influenza & Respiratory Illness Activity Report

Week A (H1N1) pdm09 A H3 A (not subtyped) B 2016-17 + by PCR 2017-18 + by PCR 2018-19 + by PCR 2019-20 + by PCR 2020-21 + by PCR

40 3 1 025 0 013175 0 013

41 1 2 019 0123 034247 06 01

42 0 1 0 1 129 0898 095238 03 0108

43 078 06924 202899 0

44 174 1139 137112 02

45 351 03525 332577 0

46 482 034404 331263 01

47 633 047733 859206 01

48 61 10506 992443 0

49 557 06435 116883 01

50 1063 200222 173616 003

51 2219 38961 25333 01

52 2662 6875 287995 01

53 2373 689858 247537 0

1 2608 8645 238247 009

2 3128 11334 291924 0

3 2973 15812 285285 016

4 256 198343 313398 006

5 2463 219485 330324 0

6 2433 257567 359588 0065

7 229 260141 341712 0073

8 2105 255621 354538 0

9 1938 267438 277136 018

10 1745 239014 22092 0

11 1801 224066 928172 012

12 1689 1891 510657 0

13 1711 192825 105079 0

14 1463 105078 0 0045

15 1132 887902 0 0

16 144 743062 0 0

17 1196 554455 0 0

18 529 481348 0 0

19 538 441176 0

0

0

5

10

15

20

25

30

35

40

45

50

0

5

10

15

20

25

30

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Percent of Positive Molecular TestsN

umbe

r of P

ositi

ve M

olec

ular

Tes

ts

MMWR Week

B

A (not subtyped)

A H3

A (H1N1) pdm09

2017-18 + by PCR

2018-19 + by PCR

2019-20 + by PCR

2020-21 + by PCR

2021-22 + by PCR

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 8

Laboratory Surveillance

The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories voluntarily submitting testing data weekly These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV) Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses MDH-PHL provides further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage Tracking the laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the influenza season as well as prevalence of disease in the community

Specimens Positive for Influenza by Molecular Testing by Week

of molecular tests positive this week of molecular tests positive last week

01 01

Beginning in 2016-17 laboratories report results for rapid molecular influenza tests in addition to RT-PCR results

dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 9: Weekly Influenza & Respiratory Illness Activity Report

Region AB+ A+ B+ dagger2015-16 + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21 +

40 0 0 0 203 036 1145 103448 0 0

41 0 1 2 072 22 0715 232558 4 23

42 0 1 4 170 203 2916 221239 18 27

43 524 187 16344 18 12

44 196 172 2489 316742 11

45 192 347 08658 468948 32

46 240 485 315501 601589 07

47 460 734 332 95373 34

48 600 113 2247 127993 21

49 501 1109 199336 152819 31

50 788 1562 260869 237288 18

51 934 2187 405872 284537 0

52 1325 3006 919143 311344 18

53 12675 28255 8677865 2940235 265

1 1210 2645 81643 276703 081

2 1338 2899 134066 262082 22

3 1865 3389 167612 312544 0

4 2269 3316 227335 330813 0

5 2427 3239 254458 359291 28

6 2696 271 249393 360528 0

7 3081 2975 28238 368231 574

8 2756 2987 287495 342097 221

9 2689 2712 297446 350487 233

10 2990 2243 315927 309389 0

11 3028 2194 338757 226124 079

12 3082 1891 281729 136591 109

13 2704 1984 253886 407303 159

14 2369 1648 224849 188442 408

15 2180 1771 21995 219178 122

16 1810 172 149654 134771 0

17 1074 1679 149688 104167 175

18 900 148 14718 181818 159

19 980 983 137681 714

20 775 886 133891 0

Region Number + dagger2016-17 + dagger2017-18 + dagger2018-19 + dagger2019-20 + 2020-21+

40 56 1304 1489 810811 91 21

41 106 10 1327 625 10 36

42 72 65 7 493827 158 348

43 96 6767 123711 13

44 93 20408 208333 33

45 91 12381 894309 0

46 25 196429 155844 0

47 241 2227 281633 0

48 2949 29787 237013 77

49 2601 364 26378 0

50 3205 372881 251724 0

51 4051 350133 26824 59

52 3767 324009 291747 0

53 3581 358621 319404 714

1 313 37844 245742 0

2 3291 320833 262443 0

3 3006 320366 201729 105

4 3211 255937 228261 0

5 3043 304094 235474 0

6 2667 29683 190736 0

7 3041 206997 211144 435

8 2248 183871 169675 0

9 2283 214925 142857 0

10 2627 1512 881543 0

11 873 1666667 102881 0

12 1186 179916 48346 0

13 1603 115555 205882 0

14 909 903226 204082 333

15 583 958904 30303 0

16 735 34247 263158 769

17 411 84033 181818 0

18 8 289855 0

19 15 322581 454

20 1 57 15 322581 454

0

5

10

15

20

25

30

35

40

45

50

0

2

4

6

8

10

12

14

16

18

20

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19

Percentage of Rapid Antigen Influenza Tests Positive

Num

ber o

f Pos

itive

Influ

enza

Spe

cim

ens

MMWR Week

AB+ A+B+ 2016-17 +2017-18 + 2018-19 +2019-20 + 2020-21 +

Current week

0

10

20

30

40

50

60

70

80

90

100

0

25

50

75

100

125

150

175

200

225

250

275

300

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Percentage of Rapid Antigen RSV Tests Positive

Num

ber o

f Pos

itive

RSV

Tes

ts

MMWR Week

Number +

2017-18 +

2018-19 +

2019-20 +

2020-21+

2021-22+

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 9

Laboratory Surveillance (continued)MLS Laboratories ndash Influenza Testing

Specimens Positive by Influenza Rapid Antigen Test by WeekMLS Laboratories ndash RSV Testing

Specimens Positive by RSV Rapid Antigen Test by Week

Region rapid antigen influenza tests + this week

Central 1

Metro 3

Northeast 0

Northwest 0

South Central 6

Southeast 0

Southwest 0

West Central 0

Statewide (overall) 3

Region rapid antigen RSV tests + this week

Central 30

Metro 25

Northeast 0

Northwest 33

South Central 49

Southeast 37

Southwest 35

West Central 35

Statewide (overall) 35dagger The Week 53 value for these seasons is the average of Week 52 and Week 1

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 10: Weekly Influenza & Respiratory Illness Activity Report

Week COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

40 0 0 5 9 28

41 5 0 0 0 17

42 2 0 0 0 13

43

44

45

46

47

48

49

50

51

52

53

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

0

10

20

30

40

50

60

40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Num

ber P

ositi

ve b

y RT

-PCR

MMWR Week

COVID-positive Flu-positive RSV-positive Other-pathogen positive All tests negative

Current week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 10

Minnesota Influenza Incidence Surveillance Project (MIISP)

MIISP surveillance sites collect 10-20 specimens every week on patients presenting with acute respiratory illness with or without fever The graph below illustrate the number of positive results by virus family detected each week The primary purpose of these graphs is to visualize the respiratory viruses circulating in Minnesota

MIISP Testing (Outpatient) by Week

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 11: Weekly Influenza & Respiratory Illness Activity Report

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 11

Minnesota Influenza Incidence Surveillance Project (continued)

Pathogen Group Pathogen Frequency Percent of detections

All Negative None 58

Adenovirus Adenovirus 1 5

Bocavirus Bocavirus - -

Influenza Flu AH12009 - -

Flu AH1seasonal - -

Flu AH3 - -

Flu AUnknown - -

Flu AUnsubtypeable - -

Flu B - -

Parainfluenza Parainfluenza-1 - -

Parainfluenza-2 - -

Parainfluenza-3 - -

Parainfluenza-4 - -

RSVMetapneumovirus Metapneumovirus - -

RSV 5 24

Seasonal Coronavirus Coronavirus-229E - -

Coronavirus-HKU1 - -

Coronavirus-NL63 - -

Coronavirus-OC43 - -

RhinovirusEnterovirus Enterovirus - -

Rhinovirus - -

RhinovirusEnterovirus (non-differentiated) 8 38

SARS-CoV-2 (COVID-19) SARS-CoV-2 7 33

This table details the specific viruses detected during the 2020-21 Influenza season Viruses are grouped by the virus family they belong to with the exception of SARS-CoV-2 (the virus that causes COVID-19) which is singled out from the seasonal coronaviruses that regularly circulate throughout the year

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report
Page 12: Weekly Influenza & Respiratory Illness Activity Report

Minnesota Department of Health Weekly Influenza amp Respiratory Activity Report for Week Ending Oct 23 2021 | WEEK 42 Page 12

Weekly US Influenza Surveillance Report

Week 41 ending Oct 16 2021Seasonal influenza activity in the United States remains lowbull An annual flu vaccine is the best way to protect against flu and its potentially serious complicationsbull CDC recommends everyone 6 months or older get a flu vaccine by the end of Octoberbull There also are flu antiviral drugs that can be used to treat flu illness

Outpatient Illness ILINet Activity Map

This week 2 jurisdictions experienced moderate activity and no jurisdictions experienced high or very high activity

CDC National Influenza Surveillance (httpwwwcdcgovfluweekly)

  • Hospitalized Influenza Surveillance
  • Influenza-Associated Death Surveillance
  • Respiratory Disease Outbreak Surveillance School Outbreaks
  • Respiratory Disease Outbreak Surveillance LTC Outbreaks
  • Sentinel Provider Surveillance (Outpatients)
  • Laboratory Surveillance
  • Minnesota Influenza Incidence Surveillance Project (MIISP)
  • Weekly US Influenza Surveillance Report