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Page 1: Welcome to the ISHR XXI World Congress · It is my great pleasure and honor to welcome all of the colleagues to the XXI World Congress of the ISHR in San Diego. The World Congress

Welcome to the

ISHR XXI World Congress

Name: Email:

Page 2: Welcome to the ISHR XXI World Congress · It is my great pleasure and honor to welcome all of the colleagues to the XXI World Congress of the ISHR in San Diego. The World Congress
Page 3: Welcome to the ISHR XXI World Congress · It is my great pleasure and honor to welcome all of the colleagues to the XXI World Congress of the ISHR in San Diego. The World Congress

ISHR XXI World Congress | June 30, 2013 – July 4, 2013 | San Diego, California www.ishr2013.com

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Contents ISHR Executive Committee 2010-2013 ......................................................................................................... 3 2013 ISHR World Congress Organizing Committee ...................................................................................... 3 2013 ISHR World Congress Planning Committees ........................................................................................ 4 Welcome from the ISHR President ............................................................................................................... 5 Welcome from the Scientific Program Committee Chair ............................................................................. 6 Welcome from the XXI World Congress Program Chair and Co-Chair ......................................................... 7 The International Society for Heart Research ............................................................................................... 8 ISHR Administrative Offices/Staff ................................................................................................................. 8 Congress Schedule ........................................................................................................................................ 9 Floor Plans and Maps .................................................................................................................................. 23

San Diego Convention Center (SDCC), Upper Level ................................................................................ 23 Marriott Marquis & Marina Floor Plan ................................................................................................... 24

Meeting Information ................................................................................................................................... 25 About the Meeting .................................................................................................................................. 25 Assistance for Attendees ........................................................................................................................ 25 Business Center – Ground Level ............................................................................................................. 25 ECI Pre-Congress Event ........................................................................................................................... 25 Exhibits .................................................................................................................................................... 25 Family/Nursing Mothers Room ............................................................................................................... 25 FISHR Dinner ........................................................................................................................................... 25 Food and Beverage Service ..................................................................................................................... 26 Housing/Hotels ....................................................................................................................................... 26 Internet Access ........................................................................................................................................ 26 ISHR Council Meetings ............................................................................................................................ 26 Lost and Found ........................................................................................................................................ 26 Message Board ........................................................................................................................................ 26 Parking .................................................................................................................................................... 26 Poster Sessions ........................................................................................................................................ 27 Registration Hours .................................................................................................................................. 27 Registration Fees ..................................................................................................................................... 28 Restaurant, City Information, Tours and Activities ................................................................................. 28 San Diego Zoo Excursion ......................................................................................................................... 28 Social Media ............................................................................................................................................ 28 Speaker Ready/Presentation Upload Room ........................................................................................... 29 Travel and Visitor Information ................................................................................................................ 29

Awards for Excellence ................................................................................................................................. 30 Award Lectures & Presentations............................................................................................................. 30 ISHR Bing Award 2013 Finalists ............................................................................................................... 30

Selected Junior Faculty Speakers ................................................................................................................ 31 Travel Awardees.......................................................................................................................................... 32 Invited Speakers .......................................................................................................................................... 33 Poster Sessions and Numbers ..................................................................................................................... 38 Exhibitors .................................................................................................................................................... 47 NOTES.......................................................................................................................................................... 50

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ISHR XXI World Congress | June 30, 2013 – July 4, 2013 | San Diego, California www.ishr2013.com

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ISHR Executive Committee 2010-2013

Masatsugu Hori, MD, PhD, President Metin Avkiran, DSc, President-Elect Richard Moss, PhD, Secretary General Elizabeth Murphy, PhD, Treasurer Roberto Bolli, MD, Past-President

Thomas Eschenhagen, MD, Council Member Leslie Anderson Lobaugh, PhD, Heart News and Views Editor David Eisner, DPhil, J Mol Cell Cardiol Editor

ISHR gratefully acknowledges the expertise, hard work and dedication of the 2013 Organizing Committee

*****************

2013 ISHR World Congress Organizing Committee

Joan Heller Brown, PhD, Chair School of Medicine University of California, San Diego Yibin Wang, PhD, Co-Chair David Geffen School of Medicine University of California, Los Angeles

Donald M. Bers, PhD School of Medicine University of California, Davis Kirk U. Knowlton, MD School of Medicine University of California, San Diego Mark Mercola, PhD Sanford Burnham Medical Research Institute, San Diego Robert M. Mentzer, MD Donald P. Shiley Bioscience Center, San Diego Daria Mochly-Rosen, PhD School of Medicine Stanford University Richard L. Moss, PhD School of Medicine and Public Health University of Wisconsin Paul C. Simpson, MD School of Medicine University of California, San Francisco Mark A. Sussman, PhD Heart Institute San Diego State University James N. Weiss, MD David Geffen School of Medicine University of California, Los Angeles

Page 5: Welcome to the ISHR XXI World Congress · It is my great pleasure and honor to welcome all of the colleagues to the XXI World Congress of the ISHR in San Diego. The World Congress

ISHR XXI World Congress | June 30, 2013 – July 4, 2013 | San Diego, California www.ishr2013.com

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2013 ISHR World Congress Planning Committees

ISHR Scientific Program Planning Committee Richard L. Moss, PhD, Chair | School of Medicine and Public Health, University of Wisconsin Donald M. Bers, PhD | School of Medicine, University of California, Davis Sian E. Harding, PhD | National Heart & Lung Institute Walter J. Koch, PhD | Jefferson Medical College Masahiko Kurabayashi, MD, PhD | School of Medicine, Gunma University Salvatore Pepe, PhD | Murdoch Children's Research Institute Rainer Schulz, MD, PhD | Justus-Liebig University Giessen Martin Vila-Petroff, PhD | Facultad de Ciencias Medicas Rui-Ping Xiao, MD, PhD | National Institute on Aging, NIH, DHH 2013 ISHR World Congress Local Planning Committee Eric Adler, MD | School of Medicine, University of California, San Diego Brian Black, PhD | School of Medicine, University of California, San Francisco Ju Chen, PhD | School of Medicine, University of California, San Diego Neil C. Chi, MD, PhD | School of Medicine, University of California, San Diego Shu Chien, MD, PhD | University of California, San Diego Shaun R. Coughlin, MD, PhD | School of Medicine, University of California, San Francisco Anthony N. DeMaria, MD | School of Medicine, University of California, San Diego Wolfgang H. Dillmann, MD | School of Medicine, University of California, San Diego Sylvia Evans, PhD | School of Medicine, University of California, San Diego Chris C. Glembotski, PhD | San Diego State University Josh Goldhaber, PhD | David Geffen School of Medicine, UCLA Roberta Gottlieb, MD | San Diego State University Barry H. Greenberg, MD | School of Medicine, University of California, San Diego Asa B. Gustafsson, PhD | School of Medicine, University of California, San Diego Paul Insel, MD | School of Medicine, University of California, San Diego Joel S. Karliner, MD | School of Medicine, University of California, San Francisco Robert A. Kloner, MD | Heart Institute of the Hospital of the Good Samaritan Joel Linden, PhD | La Jolla Institute for Allergy & Immunology W. Robb MacLellan, MD | David Geffen School of Medicine, UCLA Eduardo Marban, MD, PhD | Heart Institute Cedars - Sinai Medical Center Andrew McCulloch, PhD | University of California, San Diego Charles E. Murry, MD | School of Medicine, University of Washington Sangiv Narayan, MD | St. John’s Medical College & Hospital Hemal Patel, PhD | School of Medicine, University of California, San Diego Kirk L. Peterson, MD | School of Medicine, University of California, San Diego Peipei Ping, PhD | David Geffen School of Medicine, UCLA Robert Ross, MD | School of Medicine, University of California, San Diego Farah Sheikh, PhD | School of Medicine, University of California, San Diego Deepak Srivastava, MD | School of Medicine, University of California, San Francisco Jill C. Tardiff, MD, PhD | College of Medicine, University of Arizona Rong Tian, MD, PhD | School of Medicine, University of Washington Sam Tsimikas, MD | School of Medicine, University of California, San Diego Francisco J. Villarreal, MD, PhD | School of Medicine, University of California, San Diego Thomas M. Vondriska, PhD | David Geffen School of Medicine, UCLA Joseph C. Wu, MD | School of Medicine, Stanford University

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Welcome from the ISHR President

Dear Colleagues, It is my great pleasure and honor to welcome all of the colleagues to the XXI World Congress of the ISHR in San Diego. The World Congress which meets every three years is a good opportunity for our colleagues from seven sections all over the world to get together and discuss the recent progress in the cardiovascular research. The XXI World Congress is effectively organized by Professors Joan Heller Brown and Yibin Wang and their colleagues, at one of the most beautiful sites in the world, San Diego. The program is composed of the exciting symposia, Award and keynote lectures in which cutting edge science will be discussed. For young researchers, Richard Bing Young Investigator Award competition and early career investigator (ECI) program are provided as well as the poster presentation. Meeting with face-to-face discussion is the shortest way for treasure hunting and friendship making. As a president of the ISHR, I cordially invite all of the colleagues to participate in this exciting World Congress in San Diego. Finally, I would like to extend my sincere thanks to Joan, Yibin and Rick Moss (program committee chair) for their devoted contributions in organizing the Congress, looking forward to a great success.

Dr. Masatsugu Hori President ISHR 2010-2013 ISHR XX World Congress Chair President, Osaka Medical Center for Cancer and Cardiovascular Diseases Professor-emeritus, Osaka University School of Medicine, Osaka, Japan

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Welcome from the Scientific Program Committee Chair

Welcome to the 2013 World Congress of the International Society for Heart Research! The ISHR is among the leading societies internationally dedicated to understanding the mechanisms of inherited and acquired diseases of the heart and cardiovascular system, with the ultimate goal of improving clinical approaches to treatment and prevention of disease. This year’s World Congress promises to deliver reports of substantive progress in our understanding of the determinants of cardiac health and disease. Nearly 180 speakers from all seven of our regional sections will make oral presentations addressing the primary themes of the meeting:

Emerging Concepts of Cardiac Regulation: Beyond the Genome Ion Channel Mechanisms and Therapeutic Targets for Arrhythmias Cardioprotection New Insights into Cardiac Dysfunction New Mechanisms of Cardioprotection and Injury Regenerative Medicine for Heart Diseases Signaling in Cardiac Disease and Therapy Translation from Cardiac Research to Therapies

The Scientific Program Committee in collaboration with the Local Organizing Committee has drafted a schedule of 40 symposia that ensures that these themes are carried through the three and a half days of the Congress. The scientific program notably features participation by investigators at early career stages: a half-day pre-Congress session involving presentations by Early Career Investigators, symposium presentations by faculty at ranks equivalent to assistant professor, and co-chairing of all the symposia that comprise the meeting. The schedule has been tailored to ensure that poster sessions occur during “prime time” each day. The outstanding poster from each of the three sessions selected by the judges will be recognized by a poster prize to the primary author. On behalf of the ISHR, I extend deepest appreciation to the Scientific Program Committee and the Local Organizing Committee for their thoughtful and dedicated work in bringing this World Congress to fruition. I especially thank Joan Heller Brown and Yibin Wang, Chair and Co-Chair of the Local Organizing Committee for their initiative in hosting this meeting in San Diego, for their leadership in planning meeting logistics, and for their relentless pursuit of excellence in organizing the meeting. The work involved in this undertaking is demanding and can at times be consuming, but through it all, Joan and Yibin and their organizing committee have worked tirelessly to ensure that this World Congress is compelling and memorable. To reap the full benefit of the World Congress, I encourage you to take part in the General Assembly and all social activities as a means to learn more about the missions of the ISHR and to meet ISHR colleagues from around the globe.

On behalf of the Scientific Program Committee and the Local Organizing Committee, I wish you a very successful meeting! Thank you for your commitment to the missions and programs of the ISHR.

Richard L. Moss, PhD Secretary General, ISHR Chair, Scientific Program Committee

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Welcome from the XXI World Congress Program Chair and Co-Chair

Dear Friends and Colleagues, It is with great pleasure and anticipation that we welcome you to the XXI ISHR World Congress in San Diego. Cardiovascular research is undergoing breath-taking progress with tremendous advances in traditional and emerging new disciplines. The symposia developed and sponsored by the International Program Committee and ISHR Sections, complemented by those conceived and funded locally, encompass a remarkably broad and timely range of topics. Most important is the outstanding line up of invited speakers and stellar Award recipient lectures to be given by scientists at the forefront of our field. At this year’s Congress we have also made a special effort to promote and recognize the successes of our Early Career Investigators (ECIs) as part of the central mission of the ISHR. In addition to the pre-Congress ECI Workshop there is an ISHR International Poster Award Competition and the prestigious Richard J. Bing Young Investigator Competition; also we have incorporated 18 short talks in the final symposia specifically selected from junior investigators based on their submitted abstracts, and offered symposia chair opportunities to many other early career investigators.

The Marriott Hotel and Marina have been highly accommodating as their needs and ours have changed since the time of our original planning more than 5 years ago, and the San Diego Convention Center should provide a luxurious amount of space to meet formally and informally while enjoying the spectacular harbor views and Southern California breezes. We sincerely thank our sponsors and exhibitors, in particular those who have been unexpectedly generous with their support which has been essential to the realization of this meeting. The staff at Strategic Results has been incredible, in particular Jackie Burkhardt who has been there to help with absolutely everything, including volunteering to do all the worrying for me, and has always kept her optimism and composure. Finally, without the sage advice and stewardship of Rick Moss and Tish Murphy we would have been overwhelmed with all of the arrangements and decisions to be made. We hope the Congress will be a memorable experience for each of you, and expect that the fine weather, unequaled collegiality, and exciting science will drive collaborations and advance our field from bench to bedside and beyond. Thank you all for being an important part of this event and we hope you enjoy the congress and your visit in San Diego. With warm wishes,

Joan Heller Brown, PhD, Chair Distinguished Professor and Chair Department of Pharmacology University of California, San Diego

Yibin Wang, PhD, Co-Chair Professor of Molecular Medicine Departments of Anesthesiology, Physiology and Medicine David Geffen School of Medicine, UCLA

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The International Society for Heart Research ISHR Administrative Offices/Staff Leslie Anderson Lobaugh, PhD Executive Secretary P.O. Box 52643, Durham, NC 27717-2643 Fax: 919-493-4418 • E-mail: [email protected] ISHR Web site: www.ishrworld.org • World Congress Web Site: www.ishr2013.com

ISHR Section Leadership

Australasian Section Lea M. Delbridge, PhD, President David Saint, PhD, Secretary Chinese Section Rui-Tai Hui, President Qi Chen, Vice-President Youyi Zhang, Vice-President Huang-Tian Yang, MD, PhD, Vice-President Yi Zhu, MD, Secretary Liling Wu, MS, Treasurer European Section Peter Ferdinandy, MD, PhD, President Denise Hilfiker-Kleiner, PhD, Secretary/Treasurer Indian Section K. K. Talwar, President S. K. Gupta, MD, Secretary General R.K. Goyal, Finance Secretary N.K. Ganguly, Chief Patron C.C. Kartha, International Advisor Japanese Section Issei Komuro, MD, PhD, President Keiichi Fukuda, MD, PhD, President-Elect Masatsugu Hori, MD, Past-President Yoshikiko Saito, Secretary General T. Murohara, Treasurer Latin American Section Paulina Donoso, MSc, President Martin Vila-Petroff, PhD, Past-President Gina Sanchez, Secretary Alejandro Aiello, Treasurer North American Section Elizabeth Murphy, PhD, President Jennifer Van Eyk, PhD, Secretary Evangelia Kranias, PhD, Treasurer

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Congress Schedule

ECI Pre-Congress Workshop

10:00 AM ECI Pre-Congress Registration

11:00 AM Does GAPDH acts a mitochondrial trans-S-nitrosylase in the myocardium?Mark Kohr, Johns Hopkins, USA

11:15 AM High passive cardiomyocyte stiffness in a mouse model of hypertrophic cardiomyopathyAref Najafi, VU University, Netherlands

11:30 AM Aging-related cardiomyocyte functional decline is sex- and angiotensin II-dependentKimberley Mellor, University of Auckland, New Zealand

11:45 AM Aldosterone mediates the cardiac sodium/bicarbonate transporter (NBC) activation through a

non-genomic and ROS-dependent mechanismAlejandro Orlowski, UNLP-CONICET, Argentina

12:00 PM Peroxisome proliferator-activated receptor delta mediates the vascular benefits of metformin

through inhibiting endoplasmic reticulum stress in diet-induced obese mice

Wai San Cheang, The Chinese University of Hong Kong, China

12:15 PM A novel mechanism of CaMKII activation during hyperglycemiaJeff Erickson, UC Davis, USA & University of Otago, New Zealand

12:30 PM Lunch1:30 PM MiRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy

Melanie Ricke-Hoch, Hannover Medical School, Germany1:45 PM The cAMP/PKA pathway contributes to sex differences in SR calcium release in murine

cardiomyocytesRandi Parks, Dalhousie University, Canada

2:00 PM The Balance of fatty acid contents in macrophages is crucial for prevention against cardiac

remodeling induced by pressure overloadJin Endo, Keio University School of Medicine, Japan

2:15 PM Characterising L-type Ca2+ channel function and mitochondrial function in two murine models

of familial hypertrophic cardiomyopathyHelena Viola, University of Western Australia, Australia

2:30 PM Career Development Workshop: Publishing - The Do’s, Don’ts, and DilemmasElizabeth Murphy (USA) and Dr David Eisner (UK)

3:30 PM Social Hour

World Congress

3:00 PM World Congress Registration Opens

4:30 PM Welcome 4:35 PM Distinguished Leader Award Presentation

Alicia Mattiazzi, MD4:40 PM Outstanding Investigator Award Lecture

Deepak Srivastava, MD5:40 PM Keith Reimer Award Lecture

Karin Sipido, MD, PhD

6:40 PM Opening Reception

Location: Lobby 6

Location: 6A

Location: San Diego Marriott Marquis & Marina, Coronado Terrace

Sunday, June 30, 2013

Location: 5AB Foyer

Location: 5AB

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7:00 AM World Congress Registration Opens

Location: 6A8:30 AM Research Achievement Award Lecture

Eric Olson, University of Texas Southwestern Medical Center at DallasLocation: Bayside Corridor9:30 AM Refreshments

Symposium 1 Myocardial autophagy - for better or for worse?

Location: 6D Session Chair(s): Lea Delbridge, University of Melbourne, Australia& Sonia Singh, Experimental

Pharmacology Hamburg

10:00 AM Mitophagy in Cardioprotection Roberta A Gottlieb, San Diego State University

10:30 AM Autophagy, mitochondria and sterile inflammation Kinya Otsu, King’s College London, United Kingdom

11:00 AM Autophagy, angiotensin II and insulin resistance Lea M D Delbridge, University of Melbourne, Australia

11:30 AM The role of autophagy in cardiac failure and aging Masatsugu Hori, Osaka University Graduate School of Medicine, Osaka, Japan

Symposium 2 Thin filament function in cardiac health and disease

Location: 6E Session Chair(s): Andrew McCulloch, University of California, San Diego & John Seubert,

University of Alberta 10:00 AM Novel arrhythmia mechanisms caused by sarcomeric mutations

Bjorn Knollman, Vanderbilt University10:30 AM Mechanisms of lamin AC cardiomyopathies

Giselle Bonne, Inserm Institut de Myologie, Paris, France11:00 AM Allosteric effects of thin filament mutations on sarcomeric assembly and function

Ji l Tardiff, University of Arizona11:30 AM Molecular Dynamics of Bio-Sensing Troponins

Joseph Metzger, University of Minnesota

Symposium 3 Ca2+

signalling and cardiac pacemaker function

Location: 6F Session Chair(s): Tomoaki Higo, Osaka University & Elizabeth Woodcock, Baker IDI Heart and

Diabetes Institute

10:00 AM The emergence of rhythmicity of the heart’s pacemaker cells is phosphorylation-dependentEdward Lakatta, Gerontology Research Center, NIH

10:30 AM IP3R Ca2+ signalling in cardiac pacemaker tissue Yue-kun Ju, University of Sydney, Australia

11:00 AM The regulation of P21 activated kinase 1 on Ca2+ signalling and electrical activity in cardiac

myocytes

Ming Lei, University of Manchester, United Kingdom

11:30 AM Voltage and calcium dependent arrhythmic mechanisms Barry London, University of Iowa

Symposium 4 Protein kinases as therapeutic targets

Location: 11AB Session Chair(s): Katsuki Okada, Osaka University Graduate School of Medicine & Yibin

Wang, University of California, Los Angeles10:00 AM Calmodulin-dependent protein kinase II

Mark Anderson, University of Iowa10:30 AM The molecular basis for dual PKC-delta signalling modes in cardiomyocytes

Susan Steinberg, Columbia University11:00 AM Targeting PI3 kinase signalling to improve function of the failing heart

Julie McMullen, Baker Heart Research Institute, Australia11:30 AM Targeting p38 in amyloidosis

Ronglih Liao, Harvard Medical School

Symposia 1 -6

Monday, July 1, 2013

Location: Lobby 6

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Symposium 5 The language & function of microRNAs

Location: 6C Session Chair(s): Gerald Dorn, Washington University in St. Louis & Naoto Muraoka, Keio

University School of Medicine, Tokyo, Japan9:50 AM microRNAs in cardiac remodeling (Keynote)

Eric Olson, University of Texas Southwestern Medical Center at Dallas

10:20 AM Biomarkers in the postgenomic Era: MicroRNAs, lipid species and protein targets across the

cardiovascular continuum

Manuel Mayr, King’s College London, United Kingdom10:45 AM microRNAs in cardiac development and regeneration

Da-Zhi Wang, Children’s Hospital, Harvard 11:10 AM Regulatory RNAs and the failing heart

Thomas Thum, Hannover Medical School, Germany11:35 AM hiPSC screening to develop RNA therapeutics for heart failure

Mark Mercola, Sanford Burnham Medical Research Institute, San Diego

Symposium 6 Stem cells in the developing and adult cardiovascular system

Location: 5AB Session Chair(s): Alex Zambon, University of California, San Diego & Sean Wu, Stanford

University School of Medicine10:00 AM Lessons from embyronic development for myocardial regeneration in the adult

Michel Puceat, INSERM, Paris, France10:30 AM Adult Cardiac Stem Cells: You Can't Turn Back the Clock, but You Can Wind It Up Again

Mark Sussman, San Diego State University11:00 AM Stem Cells and myocardial aging

Piero Anversa, Brigham and Women’s Hospital, Harvard Medical School11:30 AM Does Is1-1 mark a progenitor population in the postnatal heart?

Thomas Eschenhagen, University Hospital Hamburg-Eppendorf, Germany

12:00 PM Poster Session 1 (PS1) & Lunch

Symposium 7 Gasotransmitters in cardioprotection

Location: 6D Session Chair(s): David Lefer, Emory University School of Medicine 2:00 PM Hydrogen sulfide signalling and cardioprotection

Gary F. Baxter, Cardiff University, United Kingdom2:30 PM NO signalling in cardioprotection 

Peter Ferdinandy, University of Szeged, Hungary

3:00 PM Carbon monoxide signalling in cardioprotection Roberto Motterlini , ISERM, Paris, France

3:30 PM S-nitrosylation and cardioprotection Elizabeth Murphy, NHLBI, Bethesda, US

4:00 PM Trimetazidine attenuates cardiac dysfunction in endotoxemic mice through a modulation of

inflammatory responseChen Chen, Tongji Hospital, Tongji Medical College, HUST, China

Symposium 8 Myosin binding protein C: a modulator of myocardial dysfunction

Location: 6E Session Chair(s): Sarah Franklin, University of Utah & Richard Moss, University of Wisconsin

2:00 PM Altered cMyBP-C phosphorylation in human cardiomyopathy – cause or consequence Jolanda van der Velden, VU University Medical Center, Amsterdam

2:30 PM Actin binding bymyosin-binding protein C  Samantha Harris, University of California, Davis

3:00 PM Cardioprotection by myosin binding protein C Jeff Robbins, Cincinnati Children's Hospital

3:30 PM Myosin binding protein C mutations and hypertrophic cardiomyopathyLucie Carrier, University Medical Center Hamburg-Eppendorf, Germany

4:00 PM SREBP2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced

atherosclerosis susceptibility

Han Xiao, Peking University Third Hospital, Beijing, China

Symposia 7 - 12 (Junior Faculty Presentations)

Location: Sails Pavilion

Monday, July 1, 2013

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Symposium 9 Physiopathology of the heart at supraphysiological pacing frequenciesLocation: 6F Session Chair(s): Alejandro Aiello, Centro de Investigaciones Cardiovasculares & Eric Larson,

University of Colorado, Denver 2:00 PM Action potential alterations in ventricular tachycardia

Ariel Escobar, University of California, Merced2:30 PM Mechanisms underlying sodium overload-induced arrhythmias 

Martin Vila Petroff, Universidad de La Plata, Argentina3:00 PM Impaired calcium release and early afterdepolarizations in mice harboring a RyR2 loss-of-

function mutationHector Valdivia, University of Michigan

3:30 PM Electrical therapy of severe arrhythmias: searching for more efficient and safer strategiesRosana Bassani, Universidad de Campinas, Brazil

4:00 PM A novel role for mechanical cell-cell junction proteins in sinus node functionFarah Sheikh, University of California, San Diego

Symposium 10 Chocolate: cocoa flavanoids and cardiovascular healthLocation: 11AB Sponsored by Hershey

Session Chair(s): Dorothy Vatner, University of Medicine and Dentistry, New Jersey2:00 PM Chocolate consumption and cardiovascular risk

L. Djousse, Brigham and Women's Hospital, Harvard Medical School

2:30 PM Effects of cacao flavanols on endothelial biology and modulation of blood pressure 

Cesar Fraga, University of Buenos Aires, Argentina

3:00 PM Epicatechin effects on cardiac and skeletal muscle bioenergetics Francisco Villarreal, University of California, San Diego

3:30 PM Mechanisms underlying reductions in cardiometabolic risks with cacao flavanols 

Sruti Shiva, University of Pittsburgh

4:00 PM Natural killer T cells are involved in aortic valvular calcification via inhibiting osteoclastic

differentiation in uremic apolipoprotein-E deficient miceNaoki Ishimori, Hokkaido University, Japan

Symposium 11 Systems approaches with next generation genomics and proteomics Location: 6C

Session Chair(s): Eric Olson, UT Southwestern Medical Center

2:00 PM Systems analysis of the cardiac microRNA-mRNA interactome: What is epitranscriptional

regulation? 

Gerald Dorn, Washington University Center for Pharmacogenomics

2:30 PM Remodeling chromatin structure in heart failure: Proteomic insights 

Qing Wang, Cleveland Clinic Foundation

3:00 PM Global gene regulation network in cardiac development and diseases 

Silke R. Sperling, Max Planck Institute for Molecular Genetics, Berlin, Germany

3:30 PM miRNA and global gene regulation in heart during pathological remodeling Maha Abdellatif, New Jersey Medical School

4:00 PM A polymorphism in the PDE3A gene promoter that prevents cAMP-induced Increases in

transcriptional activity, and may protect against PDE3A inhibitor drug toleranceCarmen Sucharov, University of Colorado Denver

Monday, July 1, 2013

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Symposium 12 Signalling in ischemic injury Location: 5AB Session Chair(s): Gerd Heusch, Essen University, Germany & David Roth, University of

California, San Diego

2:00 PM CaMKII activation: opposing roles during ischemia/reperfusion

Alicia Mattiazzi, University of La Plata, Argentina2:30 PM Caveolin and caveolae in ischemia reperfusion injury

Hemal Patel, University of California, San Diego3:00 PM Cardioprotective effects of MST1 

Jun Sadoshima, University of Medicine and Dentistry of New Jersey

3:30 PM STAT signalling in ischemia/reperfusion injury Gerd Heusch, Essen University,  Germany

4:00 PM Cardiac Macrophages Facilitate Atrioventricular Conduction and Right Ventricular Function

after Right Ventricular Pressure OverloadKatsuhito Fujiu

4:10 PM Richard J Bing Young Investigator Competition

5:10 PM Servier Award Ceremony, ISHR European Section

5:30 PM International Council Meeting 1, Old and New Councils

Location: 6A

Location: 3

Monday, July 1, 2013

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7:00 AM World Congress Registration Opens

8:00 AM Peter Harris Award LectureMasatsugu Hori, MD, PhD

Location: Bayside Corridor9:00 AM Refreshments

Symposium 13 Mitochondrial permeability transition pore (PTP) regulation

Location: 6D Session Chair(s): Sara Menazza, National Institutes of Health & Anne Murphy, University of

California, San Diego

9:30 AM Regulation of PTP opening by hexokinase 2 binding

Andrew Halestrap, Bristol University, United Kingdom10:00 AM The permeability transition pore forms from dimers of FOF1 ATP synthase

Paolo Bernardi, University of Padua, Italy10:30 AM Mitochondrial microRNA and mitochondrial dysfunction 

Charles Steenbergen, Johns Hopkins Medical Institutes

11:00 AM Evidence and questions for conditioning-like protective effects in human hearts Michel Ovize, INSERM, Lyon, France

11:30 AM Akt phosphorylates HK-II at Thr473 and increases mitochondrial HK-II association to protect

cardiomyocytesShigeki Miyamoto, University of California, San Diego

Symposium 14 The giant protein titin in heart disease

Location: 6E Session Chair(s): Wolfgang Linke, Ruhr University Bochum, MA & Romina G. Díaz, Centro de

Investigaciones Cardiovasculares, UNLP, Argentina

9:30 AM Titin kinase as a mechanical signalling hub in the cardiac sarcomere—involvement in hereditary

cardiomyopathy 

Mathias Gautel, King’s College London, UK10:00 AM Role of titin in heart function and disease  

Henk L. Granzier, University of Arizona10:30 AM Titin phosphorylation in human systolic and diastolic heart failure 

Wolfgang A. Linke, Ruhr University Bochum, MA

11:00 AM The cross-talk of two giants: what happens when obscurin fails to bind titin

Katia Kontrogianni-Konstantopoulos, University of Maryland

11:30 AM A muscle-specific variant of the formin family member FHOD3 maintains thin filament integrity

in cardiomyocytes and is down-regulated in heart failureElisabeth Ehler, King's College London, United Kingdom

Symposium 15 Late Na+ current as a Therapeutic Target

Location: 6F Session Chair(s): Andrew Edwards & Hugh Clements-Jewery, West Virginia School of

Osteopathic Medicine

9:30 AM The anti-anginal agent ranolazine is a potent anti-arrhythmic agent Robert Kloner, University of Southern California

10:00 AM Inhibition of late Na+ current: Ranolazine and beyondLuiz Belardinelli , Gilead Sciences

10:30 AM Late Na+ current in pathological conditions Lars Maier, University of Göttingen, Germany

11:00 AM Late Na current, cellular Na+ loading and arrhythmogenesis  Eleonora Grandi, University of California, Davis

11:30 AM Polycystin-1 regulates cardiac hypertrophy via the l-type calcium channelZully Pedrozo, Universidad de Chile

Tuesday, July 2, 2013

Location: Lobby 6

Symposia 13 - 18 (Junior Faculty Presentations)

Location: 6A

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Symposium 16 New aspects of β-adrenergic signalling in the heart

Location: 11AB Session Chair(s): Burns C. Blaxall, Cincinnati Children's Hospital Medical Center & Paul Insel,

University of California, San Diego

9:30 AM Non-classical signalling through beta-adrenergic receptors 

Martin Lohse, University of Würzburg, Germany

10:00 AM β2-adrenergic signalling in cardiomyopathy

Sian Harding, Imperial College, United Kingdom

10:30 AM β-arrestin-mediated G protein-coupled receptor signalling Howard Rockman, Duke University

11:00 AM β3 adrenoceptors and cardiac signalling

Jean-Luc Balligand, Catholic University of Louvain, Brussels, Belgium

11:30 AM β-adrenergic activation inhibits PKD activation by Gq-coupled agonists by preventing its

intracellular translocation

Julie Bossuyt, University of California, Davis

Symposium 17 Epigenetic mechanisms in cardiac hypertrophy and failure: Role of HDACs

Location: 6C Session Chair(s): Metin Avkiran, King’s College London & Donald Menick, Medical University of

South Carolina

9:30 AM The cardiac epigenome in heart failure

Roger Foo, University of Cambridge Department of Medicine, United Kingdom10:00 AM Isoform-Specific Roles for HDACs in the Control of Cardiac Hypertrophy and Fibrosis

Timothy McKinsey, University of Colorado10:30 AM Novel kinase-dependent and independent pathways for HDAC regulation

Metin Avkiran, King’s College London, United Kingdom

11:00 AM HDAC regulation of autophagy in cardiac remodellingJoseph Hill, University of Texas Southwestern Medical Center at Dallas

11:30 AM Role of autophagy in Epac- induced cardiac myocyte hypertrophyFrank Lezoualc'h, Inserm, University Toulouse III, France

Symposium 18 Stem cells in disease modeling and cardiac repair

Location: 5B Session Chair(s): Paul Burridge, Stanford University & Loren Field, Indiana University

9:30 AM Regenerating the heart of a non-human primate

Chuck Murry, University of Washington10:00 AM Fetal chimerism in repair of maternal myocardium 

Hina Chaudhry, Mount Sinai Medical Center

10:30 AM What has proliferative signalling taught us about myocardial regeneration?Loren Field, Indiana University

11:00 AM Induced pluripotent stem cells: arrhythmia models and beyond  

Lior Gepstein, Technion University, Haifa, Israel

11:30 AM Transplantation of Mesenchymal Cells Rejuvenated by Delivery of Telomerase and Myocardin

Genes Promotes Revascularization and Tissue RepairRosalinda Madonna, University of Chieti, Italy

11:40 AM Poster Session 2 (PS2) & LunchLocation: Sails Pavilion

Tuesday, July 2, 2013

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Symposium 19 The Battle for Mitochondrial REDOX Regulation

Location: 6D Bayer Yakuhin Symposium - in Memory of Howard E Morgan (ISHR President 1983-86)

Session Chair(s): Katsuhito Fujiu, The University of Tokyo & Charles Steenbergen, Johns

Hopkins University 1:30 PM Multifunctional role of pyridine nucleotide redox status in the cardiomyocyte 

Brian O'Rourke, Johns Hopkins University School of Medicine2:00 PM Oxidative stress and programmed necrosis 

Chris Baines, University of Missouri, Columbia2:30 PM NADPH-dependent REDOX control in the mitochondrial inner membrane 

Salvatore Pepe, University of Melbourne, Australia3:00 PM Mitochondrial ROS regulation:  What Doesn't Kill You Makes You Stronger

James Weiss, University of California, Los Angeles

Symposium 20 Inflammation in cardiac healing and remodeling

Location: 6E Canon Symposium - in Memory of Normal R Alpert (JMCC Editor 1993-98)

Session Chair(s): Han Xiao, Peking University Third Hospital & Yi Zhu, Tianjin Medical

University 1:30 PM Role of cardiac innate immunity in repair and remodeling of the heart 

Douglas Mann, Washington University2:00 PM Autoantibodies in cardiac remodelling   

Roland Jahns, University of Würzburg,  Germany2:30 PM NF-κB signalling in myocardial survival

Lorrie Kirshenbaum, Institute of Cardiovascular Sciences, University of Manitoba, Canada3:00 PM Inflammation and aging cause heart failure 

Issei Komuro, Chiba University, Japan

Symposium 21 Evolving concepts in arrhythmogenesis

Location: 6F Session Chair(s): Robin Shaw, University of California, San Francisco, Timothy Kamp,

University of Wisconsin1:30 PM The heart’s brain – autonomics & arrhythmias

Kalyanam Shivkumar, University of California, Los Angeles2:00 PM Role of the sympathetic nervous system in triggered arrhythmias 

Crystal Ripplinger, University of California, Davis2:30 PM Gap junctions & arrhythmias 

Robin Shaw, University of California, San Francisco3:00 PM Repolarization reserve revisited – new insights from modeling

Zhilin Qu, University of California, Los Angeles

Symposium 22 Termination of signal transduction

Location: 11AB Session Chair(s): Alessandra Ghigo, University of Torino, Molecular Biotechnology Center &

Michael Kapiloff, University of Miami 1:30 PM A new dimension in transcriptome programming in cardiac development and disease

Yibin Wang, University of California, Los Angeles2:00 PM Novel regulators of protein phosphatases 

Evangelia (Litsa) G. Kranias, University of Cincinnati2:30 PM Compartmentalization of cyclic nucleotide signalling in the heart  

Manuela Zaccolo, University of Oxford, United Kingdom3:00 PM Termination of beta-adrenergic signaling by beta-AR associated phosphodiesterases

Yang Kevin Xiang, University of California, Davis

Symposia 19 - 24

Tuesday, July 2, 2013

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Symposium 23 Energy nutrient signaling in the heart

Location: 5AB Session Chair(s): Maengjo Kim, University of Washington & Chris Larson, Takeda California,

Inc.

1:30 PM Integration of ketone body metabolism into pathological myocardial states 

Peter Crawford, Washington University

2:00 PM Targeting fatty acid and carbohydrate oxidation in the ischemic and failing heart  Gary Lopaschuk , University of Alberta, Canada

2:30 PM Triglyceride metabolism: an unique player Doug Lewandowski, University of Il l inois at Chicago

3:00 PM Metabolic stress as cause for dysfunctional protein homeostasis in failing heart

Heinrich Taegtmeyer, The University of Texas Medical School at Houston

Symposium 24 Translational applications and implications for stem cell therapy

Location: 6C Session Chair(s): Preeti Ahuja, University of California, Los Angeles & Mark Sussman, San

Diego State University

1:20 PM Treatment of ischemic cardiomyopathy with autologous c-kit+ cardiac stem cells (Keynote)

Roberto Bolli, University of Louisvil le

2:00 PM Utilization of cardiospheres for autologous myocardial repair: a CADUCEUS trial update  

Eduardo Marban, Cedars Sinai Hospital, Los Angeles2:30 PM MicroRNAs inducing cardiac regeneration by promoting cardiomyocyte re-entry into cell cycle

Mauro Giacca, ICGEB Trieste, Italy

3:00 PM Cellular and Genetic Dissection of Cardiovascular Development and Regeneration

Neil Chi, University of California, San Diego

4:00 PM San Diego Zoo Excursion (first departure leaves at 3:45 PM)

6:30 PM FISHR Dinner (depart from the Marriott at 6:00 PM)

Sponsored in part by Fisher Scientific

Location: Il Fornaio

Location: San Diego Zoo

Tuesday, July 2, 2013

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7:00 AM World Congress Registration Opens

Symposium 25 Mechanisms of REDOX signaling

Location: 6D Session Chair(s): Ajay Shah, King’s College & Hua Linda Cai, University of Californa, Los

Angeles 8:30 AM Nox4 dependent regulation of cardiac stress responses  

Ajay M Shah, King’s College London, United Kingdom

9:00 AM Hydrogen peroxide as a signaling mediator in vascular endothelial cellsSantiago Lamas, Centro de Biología Molecular, Spain

9:30 AM Hydrogen peroxide as an EDHF Hiroaki Shimokawa, Tohoku University School of Medicine, Japan

10:00 AM Oxidative post-translational modifications and redox regulation Philip Eaton, King’s College London, United Kingdom

10:30 AM Targeting the upregulation of reactive oxygen species (ROS) subsequent to hyperglycemia

prevents type 1 diabetic cardiomyopathy in miceRebecca Ritchie, Baker IDI Heart & Diabetes Institute, Australia

Symposium 26 Cardiac Ca2+

, Na+ and pH regulation in health and disease

Location: 6E Kaito Symposium - Memory of Yoshio Ito (ISHR President 1989-92)

Session Chair(s): Steven Houser,Temple University & Alejandra Yeves, Cardiovascular Research

Center8:30 AM Regulation, localization and function of Na/K-pump in the heart 

Donald Bers, University of California, Davis9:00 AM The Na+/H+ exchanger 1: signalilng pathways leading to cardiac hypertrophy  

Shigeo Wakabayashi, National Cardiovascular Center Research Institute, Japan9:30 AM Microdomain Ca2+ activates cardiac hypertrophy

Steven Houser, Temple University 10:00 AM Calcium flux balance in health and heart failure 

David Eisner, University of Manchester, United Kingdom10:30 AM C-terminal truncations decrease phospholamban membrane localization and oligomerization

and alter the structure of the phospholamban-SERCA complexSeth Robia, Loyola University Chicago

Symposium 27 Cardio-Oncology: exploring new shores Location: 6F Session Chair(s): Kimberley Mellor, Auckland Bioengineering Institute, University of Auckland 8:30 AM Mechanisms of chemotherapy induced cardiotoxicity 

Thomas Force, Temple University School of Medicine9:00 AM PI3 kinases in cancer and cardiac protection 

Emilio Hirsch, University of Torino, Italy9:30 AM Cardiac side effects of anticancer treatments: new mechanistic insights  

Douglas B. Sawyer, Vanderbilt University (Not yet confirmed)10:00 AM New Insights into Anthracycline-Induced Cardiotoxicity

Daniel Bernstein, MD, Stanford University School of Medicine10:30 AM Ivabradine alters proliferation and α-smooth muscle actin expression in cardiac fibroblasts

Cesare Terracciano, Imperial College London, United Kingdom

Symposium 28 Cardiac GPCR signalling: New insights Location: 11AB Session Chair(s): Pilar Ruiz-Lozano, Stanford University & Nicole Purcell, University of

California, San Diego8:30 AM G-protein coupled receptor kinases (GRKs) in cardiac injury and repair

Wally Koch, Temple University School of Medicine9:00 AM G-protein signalling pathways in pressure overload-induced cardiac remodelling

Stefan Offermanns, Max-Planck-Institute for Heart and Lung Research

9:30 AM Nuclear GPCR signalling in the heart   Terry Hébert, Montreal Heart Institute, Canada

10:00 AM Enhancement of β-adrenergic and serotonergic signalling by natriuretic peptides Finn Olav Levy, University of Oslo, Norway 

10:30 AM Sphingosine-1-phosphate receptor-1 is required for sarcomere assembly and heart development

in vertebratesLisa Wilsbacher, University of California, San Francisco

Symposia 25 - 30 (Junior Faculty Presentations)

Wednesday, July 3, 2013Location: Lobby 6

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Symposium 29 Systems approaches to dissect cardiac disease

Location: 5AB Session Chair(s): Jennifer van Eyk, Johns Hopkins University & Sarah Scruggs, University of

California, Los Angeles

8:30 AM Proteomic and genomic investigations of cardiac chromatin structure Thomas Vondriska, University of California, Los Angeles

9:00 AM Uncovering novel mechanisms of cardiovascular disease by proteomics  Jennifer van Eyk, Johns Hopkins University

9:30 AM Mining the secretome for therapuetic targets in heart failureKenneth Walsh, Boston University

10:00 AM Subcellular and organelle-specific proteome complexity and plasticity in the heart 

Peipei Ping, University of California, Los Angeles10:30 AM TBD

TBD

Symposium 30 Translational Insights into Heart Failure

Location: 6C Sponsored in part by ResMed

Session Chair(s): Bianca Bernardo, Baker IDI Heart and Diabetes Institute & Kirk Knowlton,

University of California, San Diego 8:30 AM mRNA translation in heart 

Gianluigi Condorelli , University of California, San Diego9:00 AM Pluripotent stem cell models of inherited cardiovascular disease 

Eric Adler, University of California, San Diego9:30 AM Gene transfer therapy trials in the treatment of heart failure

Barry Greenberg, University of California, San Diego

10:00 AM Sleep in cardiac disease or sleep apnea in congestive heart failure

Atul Malhotra, Harvard Medical School, Brigham and Women's Hospital

10:30 AM Suppression of soluble Flt-1 production in endothelial cells promotes the progression of

atherosclerosis in CKD patients

Yukiji Takeda, The First Department of Internal Medicine, Japan

10:40 AM Refreshments

11:10 AM General Assembly Meeting / Janice Pfeffer Award Lecture

Michael Marber, PhD

1:10 PM Poster Session 3 (PS3) & Lunch

Symposium 31 Nitric Oxide: New oil for the heart?

Location: 6D Session Chair(s): Nitish Mahapatra, Indian Institute of Technology Madras & Anupam Mittal,

Department of Cardiology, PGIMER, Chandigarh

3:00 PM Beta-adrenoceptors and AMPK activate NOS in cardiac myocytes: direct NO detection from

new fluorescent sensors Thomas Michel, Harvard Medical School 

3:30 PM nNOS-mediated regulation of eNOS activity and myocardial function Barbara Casadei, Oxford University, United Kingdom

4:00 PM Insulin signalling and eNOS in the regulation of vascular function and metabolism E. Dale Abel, University of Utah School of Medicine

4:30 PM β3 adrenergic receptor mediated cardioprotection

David Lefer, Emory University

Location: Sails Pavilion

Location: 6A

Location: Bayside Corridor

Symposia 31 - 35

Wednesday, July 3, 2013

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Symposium 32 Myocardial injury and repair

Location: 6E Session Chair(s): Livia Hool, The University of Western Australia & Rachel Richardson, The

Univeristy of Edinburgh3:00 PM Cytoskeletal disruption and altered Ca homeostasis in cardiomyopathy

Livia Hool, University of Western Australia, Australia3:30 PM Localized Ca signalling – the subsarcolemmal architecture of failure

Christian Soeller, University of Auckland, New Zealand4:00 PM Molecular and cellular mechanism of acute ventricular remodelling and rupture after

infarction  Xiao-Jun Du, Baker IDI Heart Reearch Institute, Australia

4:30 PM Regulators of myocardial regenerative and repair responses  Enzo Porrello, University of Queensland, Australia

Symposium 33 Emerging Tools for the Identification and Study of Arrhythmias

Location: 6F Session Chair(s): James Bell, University of Melbourne & Luiz Belardinelli , Gilead Sciences3:00 PM Heterogeneity in action potential restitution as an arrhythmogenic substrate

David Saint, University of Adelaide, Australia3:30 PM Designing K+ sensitive optical sensors  

Guy Salama, University of Pittsburgh School of Medicine

4:00 PM Optogenetic approaches to investigate arrhythmias 

Marco Mongillo, Venetian Institute of Molecular Medicine, Italy

4:30 PM Using iPS-derived cardiac myocytes to investigate inherited heart diseaseTimothy J. Kamp, University of Wisconsin, Madison

Symposium 34 Mechanisms and therapies for cardiac fibrosis

Location: 11AB Session Chair(s): Lu Fang, Baker IDI Heart and Diabetes Institute & Robert Ross, University of

California, San Diego3:00 PM Signalling pathways in cardiac repair and fibrosis  

Nikolaos Frangogiannis, Albert Einstein College of Medicine3:30 PM Myocyte-fibroblast cross talk via PAR1 receptors  

Burns Blaxall, Cincinnati Children’s Hospital 4:00 PM Cardiomyocytes control cardiac fibroblast cAMP

Stefan Engelhardt, Technical University of Munich, Germany 4:30 PM Pro-and anti-fibrotic GPCRs and cardiac fibroblasts  

Paul Insel, University of California, San Diego

Symposium 35 Systems view of cardiac metabolism

Location: 6C Session Chair(s): Heinrich Taegtmeyer, University of Texas Medical School at Texas & Mohit

Jain

2:50 PM Nuclear Receptors and AMPK: Resetting metabolism (Keynote)Ron Evans, Salk Institute, La Jolla

3:30 PM Seamless networks of myocardial bioenergetics  Jianyi Jay Zhang, University of Minnesota

4:00 PM Deciphering the metabolic basis of heart failure: A systems approach Dan Kelly, Sanford Burnham Medical Research Institute

4:30 PM Mitochondrial metabolism and heart failure  Rong Tian, University of Washington

5:00 PM International Council Meeting 2, New Council

7:00 PM Closing Banquet Dinner (informal American-style barbeque)Location: San Diego Marriott Marquis & Marina, Coronado Terrace

Location: 3

Wednesday, July 3, 2013

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7:00 AM World Congress Registration Opens

8:00 AM President's Award LectureRichard Kitsis, MD

9:00 AM Refreshments

Symosium 36 Cardioprotection pathways

Location: 5AB Session Chair(s): Said Khatib, Jordan University of Science and Technology & Hemal Patel,

University of California, San Diego 9:30 AM The RISK Pathway in cardioprotection 

Derek Hausenloy, University College London, United Kingdom10:00 AM The SAFE pathway in cardioprotection

Sandrine Lecour, University of Cape Town, South Africa10:30 AM Mitochondrial proteins  in cardioprotection 

Rainer Schulz, Giessen,  Germany11:00 AM Protein folding in the sarco/endoplasmic reticulum and cardioprotection

Christopher C. Glembotski, San Diego State University

Symposium 37 Models and mechanisms in the hypertrophy-failure transition

Location: 6D Session Chair(s): Richard Moss, University of Wisconsin9:30 AM Physiologic and pathologic cardiac hypertrophy: are they two stages of the same adaptive

mechanism? 

Irene L. Ennis, Centro de Investigaciones Cardiovasculares, La Plata, Argentina10:00 AM Cardioprotective mechanisms in pythons translated to mammals 

Leslie Leinwand, University of Colorado10:30 AM miR24 in excitation-contraction uncoupling in heart failure  

Ming Xu, Peking University11:00 AM MG53-mediated diabetic cardiomyopathy

Rui-Ping Xiao, Peking University

Symposium 38 CaMKII signalling in cardiac health and disease

Location: 6E Session Chair(s): Leandro Matias Sommese, Centro de Investigaciones Cardiovasculares.La

Plata, Argentina & Xander Wehrens, Baylor College of Medicine 9:30 AM RyR phosphorylation in I/R-induced arrhythmias 

Cecilia Mundiña Weilenmann, University of  La Plata, Argentina10:00 AM CaMKII and SR Ca release control  

Derek Laver, Newcastle University, Australia10:30 AM CaMKII and pro-arrhythmogenic contexts  

James Bell, University of Melbourne, Australia11:00 AM CaMKII signalling in cardiomyocyte apoptosis 

Julieta Palomeque, University of La Plata, Argentina

Symposium 39 Approaches to the use of pluripotent stem cells in cardiac repair 

Location: 6F Session Chair(s): Yimeng Song, Peking University Health Science Center 9:30 AM Efficient generation and maintenance of cardiovascular progenitor cells from human

pluripotent stem cells

Huangtian Yang, Institute of Health Sciences, Shanghai, China

10:00 AM Cardiac iPSCs for Disease Modeling and Drug DiscoveryJoseph Wu, Stanford University School of Medicine

10:30 AM Optimization of iPS cell selection and delivery for myocardial regeneration 

Keiichi Fukuda, Keio University, Tokyo, Japan

11:00 AM Pluripotent stem cell-based cardiac regeneration—lesson from cardiac development Sean Wu, Stanford University

Symposia 36 - 40

Thursday, July 4, 2013

Location: 6A

Location: Bayside Corridor

Location: Lobby 6

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Symposium 40 Bottlenecks and opportunities in CV drug discovery

Location: 11AB Session Chair(s): Fay Lin Khong, The University of Melbourne & Paul Simpson, VA Medical

Center, University of California, San Francisco

9:30 AM The role of the academic researcher in drug discovery 

Daria Mochly-Rosen , Stanford University

10:00 AM Challenges in the development of heart failure drugs: a partnership opportunity for pharma

and academiaOrlando Bueno, Takeda Pharmaceuticals

10:30 AM Protease-activated receptors: discovery to "drug" 

Shaun Coughlin, University of California, San Francisco

11:00 AM Current Strategy in Therapeutic Development of Heart Failure Aarif Khakoo, Amgen

11:30 AM Closing Ceremony

Location: 6A

Thursday, July 4, 2013

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Floor Plans and Maps

San Diego Convention Center (SDCC), Upper Level Please note the shaded rooms are those in which symposia will be held.

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Marriott Marquis & Marina Floor Plan Walking directions from the San Diego Convention Center (SDCC) to the Marriott: Exit the Convention Center, take a left and walk along Harbor Drive, come up to front entrance of the Marriott. From the lobby, take a left towards the South Tower then take the elevator to the fourth floor.

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Meeting Information About the Meeting The scientific symposia sessions and related events for the ISHR XXI World Congress will be held at the San Diego Convention Center (SDCC), unless otherwise indicated. The San Diego Convention Center is located at 111 West Harbor Drive, San Diego, CA 92101; Tel: 619.525.5000. The Welcome Reception and Closing Banquet Dinner (informal American-style barbeque) will be held on the Coronado Terrace at the San Diego Marriott Marquis & Marina, located at 333 W Harbor Dr San Diego, CA 92101; Tel: 619.234.1500. All World Congress details are available on the ISHR XXI World Congress website at www.ishr2013.com. Please reference the website for the most up-to-date information regarding the World Congress. Assistance for Attendees Registrants with questions regarding special needs for auxiliary requirements (such as hearing assistance/sign language interpretation), housing, and transportation should contact the ISHR office in advance by e-mailing [email protected] with your specific request. NOTE: It may not be possible to accommodate last-minute and on-site requests. The San Diego Convention Center is compliant with the Americans with Disabilities Act. Business Center – Ground Level The convention center has a full-service FedEx Office business center for your convenience. Hours will be posted outside the entrance. The business center will provide an array of services including faxing, copying, express mail, packaging and printing. ECI Pre-Congress Event This year, the Congress will be hosting its first half-day event dedicated entirely to Early Career Investigators. This half-day event is comprised of 2 scientific sessions, with oral presentations from selected Early Career Investigators, followed by an interactive career development workshop with some of the leading researchers in our field. Exhibits Exhibits will be available in the Sails Pavilion during the following dates and times:

Family/Nursing Mothers Room The family room (Room 1A) is open during registration hours. The purpose of the room is to provide parents and children a place to relax during the convention. Attendees are not permitted to use this room for babysitting services. This room has been set aside for nursing mothers to have privacy. FISHR Dinner The Fellows of the International Society for Heart Research (FISHR) will attend a special dinner sponsored by the ISHR and in part by Fisher Scientific on Tuesday, July 2, 2013 at Il Fornaio Cucina Italiana, 1333 First Street, Coronado, CA. Transportation will be provided and will depart from the waterfall area in front of the Marriott Marquis at exactly 6:00 PM and will return to the Marriott Marquis at 9:45 PM.

Date Time

Monday, July 1 8:30 AM - 5:00 PM

Tuesday, July 2 8:00 AM - 4:00 PM

Wednesday, July 3 8:30 AM - 5:00 PM

Exhibit Schedule

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Food and Beverage Service ISHR will provide coffee service each morning of the World Congress in the Bayside Corridor. Lunch will be provided inside the Sails Pavilion during the poster sessions on Monday, July 1, Tuesday, July 2 and Wednesday, July 3. For your convenience, Starbucks will be open in Lobby A on the ground level of the San Diego Convention Center from 7:00 AM through 4:00 PM each day of the Congress. Housing/Hotels The official ISHR XXI World Congress hotel is The San Diego Marriott Marquis & Marina, located at 333 West Harbor Drive, San Diego, CA 92101, 1-877-622-3056. Internet Access Complimentary Wi-Fi is available in all public lobbies of the Convention Center and is limited to one session per calendar day. Instant internet is available in the lobby areas, meeting rooms and Sails Pavilion for $12.95 per 24 clock hours per device. Exhibitor Internet is available in the Sails Pavilion only and is priced at $79.99/24 hours; $159.99/3 days; $239.99/5 days. Those who wish to use the Wi-Fi service should bring their own laptop or PDA with a wireless 802.11a/g/n network card installed. To access this server, open your browser and enter your user name (email address) and password where asked, located on the left of the page. Click BUY NOW for your initial purchase or click LOGIN if you have already created an account. Both the user name and password fields are case sensitive. ISHR Council Meetings International Council Meeting 1, Old and New Councils July 1

st – 5:30 PM

International Council Meeting 2, New Council July 3rd

– 5:00 PM Please refer to the Daily Schedule for date, time and room assignment. Lost and Found The San Diego Convention Center makes every effort to return items lost at the facility back to the rightful owner during and after an event. Items recovered following an event are held for a maximum of 30 days. Unclaimed items will be disposed of after such time. To claim an item that you have lost while at a Center event, please leave a message on our lost and found hotline: 619-525-5407. Be sure to include a description of the item, event name, the date you lost it and your contact information to include a phone number. Alternatively, you can email all of this information to the administrator of the program at [email protected]. Message Board Attendees can post fliers advertising social events or upcoming meetings on the Message Board located in Lobby 6 outside of the Sails Pavilion. Exhibitors are not permitted to display materials in this area. Job seekers and employers should post their resume/job descriptions on 8½” x 11” paper on the Message Center.

Parking On-site, private vehicle parking at the Convention Center is available in the underground 1,950-space garage through an outside parking management company, not controlled by the Convention Center. Daily rates apply. The daily rate is $15, which allows for day-use parking with no in or out privileges. Please note there is no overnight or 24-hour parking. RV parking is not permitted. Off-site, private vehicle parking is also available at numerous parking lots located nearby. Go to www.visitsandiego.com for more information.

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Off-site parking is available at numerous nearby parking lots and garages in Downtown San Diego, many are within walking distance of the Center. Lots and garages are individually owned and operated, prices vary by location. Metered street parking is available in some areas. Parking meters are enforced Monday through Saturday, from 8 a.m. until 6 p.m., unless otherwise posted. Metered spots are free on Sunday and designated holidays. Meters accept nickels, dimes, quarters, and prepaid electronic debit cards. Poster Sessions Lunch will be provided for all registered attendees during the Poster Sessions. These lunchtime Poster Sessions will provide a forum for investigators from diverse disciplines to exchange new knowledge, findings, and ideas, and to lay the groundwork for future collaborations. Poster Award Competition: If you have entered the poster award competition, one outstanding poster from each of the three sessions selected by the judges will be recognized by a poster prize to the primary author at the Closing Banquet Dinner (informal American-style barbeque) on July 3 at the Marriott Marquis. The Poster Sessions will occur at the following times:

All submitted abstracts are available on the ISHR website, www.ishrworld.org. Registration Hours World Congress registration, badge, and program pickup is located in Lobby 6, located directly outside Room 6A on the Upper Level of the San Diego Convention Center and is open during the following hours:

Poster Sessions Schedule

Date Set-Up Time Poster Session Dismantle Time

Monday, July 1 (PS1) 7:00 AM - 9:00 AM 12:00 PM – 2:00 PM 3:30 PM - 5:30 PM

Tuesday, July 2 (PS2) 7:00 AM - 9:00 AM 11:40 AM – 1:30 PM 2:00 PM - 4:00 PM

Wednesday, July 3 (PS3) 7:00 AM - 9:00 AM 1:10 PM – 3:00 PM 3:00 PM - 5:00 PM

Date Time

Sunday, June 30 3:00 PM – 6:30 PM

Monday, July 1 7:00 AM – 5:00 PM

Tuesday, July 2 7:00 AM – 4:00 PM

Wednesday, July 3 7:00 AM – 5:00 PM

Thursday, July 4 7:00 AM – 10:00 AM

Registration Hours

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Registration Fees The registration fee includes many benefits: 7 Scientific Sessions with 40 Symposia, Welcome Reception, lunch for 3 days, AM breaks and a subsidized rate for the banquet. The fee does not include hotel or travel costs. Registration may be paid by check, money order or credit card.

*Post Doc (within 6 years of terminal degree) Restaurant, City Information, Tours and Activities City and surrounding area information is available at the information center, located at the bottom of the escalators on the lower level. For additional information, please inquire at the registration booth in Lobby 6. The convention center is also pleased to provide complimentary restaurant reservation services. In addition, ticket sales for city tours and other attractions are available for purchase. A booth, centrally located in Lobby B2, is staffed during peak event times. Hours of operation will be: Sunday, June 30 from 12 pm – 6 pm and Monday, July 1 through Wednesday, July 3 from 8:00 AM – 5:00 PM. San Diego Zoo Excursion If you registered for the Zoo Excursion, taking place on Tuesday, July 2, please follow this transportation schedule:

Please Note: If you didn’t register for the Zoo Excursion and would like to join the group, please visit the booth in lobby B2 of the convention center to inquire about ticket purchase and transportation options.

Social Media Attendees are encouraged to post their thoughts on exciting scientific or clinical advances they have heard about during the World Congress, and on challenges that the field will face, by using hashtag #ISHRXXI. Questions about the World Congress can be sent to Strategic Results via twitter @Strategic10. Follow ISHR on Twitter: @ISHRXXI

Registration Fees

ISHR Members: Rate (USD)

Medical Professionals 695.00$

Graduate Students 495.00$

Post Doc / Fellow * 595.00$

Registration Fees

Non-ISHR Members: Rate (USD)

Medical Professionals 795.00$

Graduate Students 595.00$

Post Doc / Fellow * 695.00$

3:45 PM 1st departure to Zoo

4:00 PM 2nd departure to Zoo 

7:00 PM 1st departure to the Marriott

7:45 PM 2nd departure to the Marriott

8:30 PM 3rd departure to the Marriott

9:15 PM Final departure to the Marriott

Depart from Entrance B at the SDCC to Zoo

 Return from Zoo to the Marriott Marquis and Marina

3:45 PM 1st departure to Zoo

4:00 PM 2nd departure to Zoo 

7:00 PM 1st departure to the Marriott

7:45 PM 2nd departure to the Marriott

8:30 PM 3rd departure to the Marriott

9:15 PM Final departure to the Marriott

Depart from Entrance B at the SDCC to Zoo

 Return from Zoo to the Marriott Marquis and Marina

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Speaker Ready/Presentation Upload Room The Speaker Ready and Presentation Upload Room (Room 10) will be open daily as follows:

Please Note: All presentations will be uploaded in the Speaker Ready Room (Room 10) and networked to the appropriate session room. Please bring your presentation to the Speaker Ready Room the day before your presentation. Audio Visual technicians will be available during the hours listed above to upload your presentation and assist you with any revisions. Personal laptops may not be used during your presentation. Travel and Visitor Information San Diego is one of the nation’s most vibrant cities. For travel and visitor information, please visit www.visitsandiego.com. Additionally, please refer to the San Diego Visitor’s Guide provided to you at registration for further information regarding transportation and local attractions.

Date Time

Sunday, June 30 1:30 PM - 4:30 PM

Monday, July 1 7:00 AM – 5:30 PM

Tuesday, July 2 7:00 AM – 4:00 PM

Wednesday, July 3 7:00 AM – 4:00 PM

Thursday, July 4 7:00 AM – 11:00 AM

Speaker Ready/Presentation Room Hours

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Awards for Excellence The International Society for Heart Research is pleased to announce the following awardees: Award Lectures & Presentations (see back cover – and daily schedule for award times) Research Achievement Award | Eric N. Olson, PhD Outstanding Investigator Award | Deepak Srivastava, MD Peter Harris Distinguished Scientist Award | Masatsugu Hori, MD, PhD Distinguished Lecture Awards:

Keith Reimer Distinguished Lecture | Karin Sipido, MD, PhD Janice Pfeffer Distinguished Lecture| Michael Marber, PhD President’s Distinguished Lecture| Richard Kitsis, MD

Distinguished Leader Award Presentation | Alicia Mattiazzi, MD, PhD ISHR Bing Award 2013 Finalists Shenuarin Bhuiyan, PhD Division of Molecular Cardiovascular Biology Cincinnati Children’s Hospital Medical Center Induced autophagy ameliorates cardiac proteinopathy Advisor: Jeffrey Robbins Dominic Del Re, PhD Department of Cell Biology & Molecular Medicine University of Medicine and Dentistry of New Jersey A mitochondrial K-Ras death complex activates Mst1 to promote myocardial ischemia/reperfusion injury Advisor: Junichi Sadoshima Chen Gao, BS University of California, Los Angeles David Geffen School of Medicine at UCLA RBFox1 mediated Alternative RNA Splicing of MEF2 Transcripts Regulates Postnatal Development and Function in Heart Advisor: Yibin Wang Zheng Maggie Huang, MD, PhD Center for Translational Medicine Temple University School of Medicine Convergence of G Protein-Coupled Receptor and Nitric Oxide Pathways determine outcome to cardiac ischemic injury Advisor: Walter Koch

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Selected Junior Faculty Speakers The International Society for Heart Research congratulates the following Junior Faculty Presentation Awardees: Bossuyt, Julie | University of California, Davis | July 2, 2013 11:30 AM - 11:40 AM

Chen, Chen | Tongji Hospital, Tongji Medical College, HUST | July 1, 2013 4:00 PM - 4:10 PM

Ehler, Elisabeth | King's College London | July 2, 2013 11:30 AM - 11:40 AM

Fujiu, Katsuhito | University of Tokyo |July 1, 2013 4:00 PM - 4:10 PM

Ishimori, Naoki | Hokkaido University |July 1, 2013 4:00 PM - 4:10 PM

Lezoualc'h, Frank | Inserm, University Toulouse III | July 2, 2013 11:30 AM - 11:40 AM

Madonna, Rosalinda | University of Chieti, Italy | July 2, 2013 11:30 AM - 11:40 AM

Miyamoto, Shigeki | University of California, San Diego | July 2, 2013 11:30 AM - 11:40 AM

Pedrozo, Zully | Facultad de Medicina, Universidad de Chile | July 2, 2013 11:30 AM - 11:40 AM

Ritchie, Rebecca | Baker IDI Heart & Diabetes Institute | July 3, 2013 10:30 AM - 10:40 AM

Robia, Seth | Loyola University Chicago | July 3, 2013 10:30 AM - 10:40 AM

Sheikh, Farah | University of California, San Diego | July 1, 2013 4:00 PM - 4:10 PM

Sucharov, Carmen | University of Colorado Denver | July 1, 2013 4:00 PM - 4:10 PM

Takeda, Yukiji | The First Department of Internal Medicine | July 3, 2013 10:30 AM - 10:40 AM

Terracciano, Cesare | Imperial College London | July 3, 2013 10:30 AM - 10:40 AM

Wilsbacher, Lisa | University of California, San Francisco | July 3, 2013 10:30 AM - 10:40 AM

Xiao, Han | Peking University Third Hospital | July 1, 2013 4:00 PM - 4:10 PM

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Travel Awardees The International Society for Heart Research congratulates the following Travel Awardees: Australasian Section Bianca Bernardo Laura Bienvenu Nga Cao Catherine Passariello Lu Fang Fay Lin Khong Norman Liaw Kimberley Mellor Padmapriya Muralidharan Paul Burridge Cheng Xue (Helena) Qin Helena Viola Chinese Section Chen Chen Dou Dou Yu-liang Feng Ling Gao Yimeng Song Cheang Wai San Shijun Wang Han Xiao Li-Mei Zhao European Section Pelin Arabacilar Anton Baysa Peter Bencsik Ayca Bilginoglu Slavka Carnicka Miroslav Ferko Miguel Frias Alessandra Ghigo Márton Gönczi Marc Hirt Aminah Loonat Rosalinda Madonna Martina Muráriková Aref Najafi

European Section (continued) Anna Pia Plazzo Antonella Ranieri Rachel Richardson Melanie Ricke-Hoch Olivia Robertson-Gray Sonia Singh Britta Stapel Justus Stenzig Mitchel Tate Zoltan Varga Indian Section Anupam Mittal Latin American Section Natália Ferreira Oshiyama Luis Gonano Jair Trapé Goulart Alejandro Orlowski Zully Pedrozo Leandro Sommese Carlos Alfredo Valverde Alejandra Yeves North American Section Preeti Ahuja Jeanne Egar Enrique Guerrero Adam Hotchkiss MaengjoKim Mark Kohr Eric Larson Won Hee Lee Sara Menazza Megan Montgomery Tiffany Nguyen Sang-Ging Ong Randi Parks Tangy Wilder

Japanese Section Yoh Arita Yoshihiro Dohi Jin Endo Katsuhito Fujiu Arata Fukushima Tomoaki Higo Gentaro Ikeda Yoshinori Katsumata Akihiko Kubota Naoto Muraoka Ryo Nakamura Taro Narumi Seitaro Nomura Katsuki Okada Jin O-Uchi Ippei Shimizu Tomokazu Sumida Kazuko Tajiri Yukiji Takeda Masamichi Yano Registration awards to Developing Countries Gisel Diaz Gabriela Gutierrez Salmean Said Khatib Nitish Mahapatra Miruna Micheu Cecilia Mundina-Weilenmann Yan Wang Li-Mei Zhao

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Invited Speakers

Abdellatif, Maha | New Jersey Medical School | July 1, 2013 2:00 PM - 4:10 PM

Abel, E. Dale | University of Utah School of Medicine | July 3, 2013 3:00 PM - 5:00 PM

Adler, Eric | University of California, San Diego | July 3, 2013 8:30 AM - 10:40 AM

Anderson, Mark | University of Iowa | July 1, 2013 10:00 AM - 12:00 PM

Anversa, Piero | Brigham & Women's Hospital, Harvard Medical School | July 1, 2013 10:00 AM - 12:00 PM

Avkiran, Metin | King's College London | July 2, 2013 9:30 AM - 11:40 AM

Baines, Christopher | University of Missouri-Columbia | July 2, 2013 1:30 PM - 3:30 PM

Balligand, Jean-Luc | Université Catholique de Louvain | July 2, 2013 9:30 AM - 11:40 AM

Bassani, Rosana | Center for Biomedical Engineering, University of Campinas | July 1, 2013 2:00 PM - 4:10 PM

Baxter, Gary | Cardiff University | July 1, 2013 2:00 PM - 4:10 PM

Belardinelli, Luiz | Gilead Sciences, Inc. | July 2, 2013 9:30 AM - 11:40 AM

Bell, James | University of Melbourne | July 4, 2013 9:30 AM - 11:30 AM

Bernardi, Paolo | University of Padova | July 2, 2013 9:30 AM - 11:40 AM

Bernstein, Daniel | Stanford University | July 3, 2013 8:30 AM - 10:40 AM

Bers, Donald | University of California, Davis | July 3, 2013 8:30 AM - 10:40 AM

Blaxall, Burns | Cincinnati Children's Hospital Medical Center | July 3, 2013 3:00 PM - 5:00 PM

Bolli, Roberto | University of Louisville | July 2, 2013 1:30 PM - 3:30 PM

Bonne, Gisele | Inserm U974 | July 1, 2013 10:00 AM - 12:00 PM

Bueno, Orlando | Takeda Pharmaceuticals | July 4, 2013 9:30 AM - 11:30 AM

Carrier, Lucie | University Medical Center Hamburg-Eppendorf | July 1, 2013 2:00 PM - 4:10 PM

Casadei, Barbara | University of Oxford | July 3, 2013 3:00 PM - 5:00 PM

Chaudhry, Hina | Mount Sinai School of Medicine | July 2, 2013 9:30 AM - 11:40 AM

Chi, Neil | University of California, San Diego | July 2, 2013 1:30 PM - 3:30 PM

Condorelli, Gianluigi | Institute of Biomedical Technologies | July 3, 2013 8:30 AM - 10:40 AM

Coughlin, Shaun | University of California, San Francisco | July 4, 2013 9:30 AM - 11:30 AM

Crawford, Peter | Washington University | July 2, 2013 1:30 PM - 3:30 PM

Delbridge, Lea | University of Melbourne | July 1, 2013 10:00 AM - 12:00 PM

Di Lisa, Fabio | University of Padova | July 2, 2013 9:30 AM - 11:40 AM

Djousse, Luc | Brigham & Women's Hospital, Harvard Medical School | July 1, 2013 2:00 PM - 4:10 PM

Dorn, Gerald | Washington University in St. Louis | July 1, 2013 2:10 PM-4:10 PM

Du, Xiao-Jun | Baker IDI Heart and Diabetes Institute | July 3, 2013 3:00 PM - 5:00 PM

Eaton, Philip | King's College London | July 3, 2013 8:30 AM - 10:40 AM

Eisner, David | University of Manchester | July 3, 2013 8:30 AM - 10:40 AM

Engelhardt, Stefan | Institute of Pharmacology and Toxicology of TUM | July 3, 2013 3:00 PM - 5:00 PM

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Invited Speakers

Ennis, Irene | Centro de Investigaciones Cardiovasculares, UNLP-CONICET | July 4, 2013 9:30 AM - 11:30 AM

Eschenhagen, Thomas | University Medical Center Hamburg-Eppendorf | July 1, 2013 10:00 AM - 12:00 PM

Escobar, Ariel | School of Engineering University of California Merced | July 1, 2013 2:00 PM - 4:10 PM

Evans, Ronald | The Salk Institute for Biological Studies | July 3, 2013 3:00 PM - 5:00 PM

Ferdinandy, Peter | Semmelweis University | July 1, 2013 2:00 PM - 4:10 PM

Field, Loren J. | Indiana University | July 2, 2013 9:30 AM - 11:40 AM

Foo, Roger | University of Singapore | July 2, 2013 9:30 AM - 11:40 AM

Force, Thomas | Temple University School of Medicine | July 3, 2013 8:30 AM - 10:40 AM

Fraga, Cesar | University of Buenos Aires | July 1, 2013 2:00 PM - 4:10 PM

Frangogiannis, Nikolaos | Albert Einstein College of Medicine | July 3, 2013 3:00 PM - 5:00 PM

Fukuda, Keiichi | Keio University | July 4, 2013 9:30 AM - 11:30 AM

Gautel, Mathias | King's College London | July 2, 2013 9:30 AM - 11:40 AM

Gepstein, Lior | Technion - Israel Institute of Technology | July 2, 2013 9:30 AM - 11:40 AM

Giacca, Mauro | International Centre for Genetic Engineering and Biotechnology ICGEB | July 2, 2013 1:30 PM - 3:30 PM

Glembotski, Chris | San Diego State University | July 4, 2013 9:30 AM - 11:30 AM

Gottlieb, Roberta | SDSU Shiley BioScience Center | July 1, 2013 10:00 AM - 12:00 PM

Grandi, Eleonora | University of California, Davis | July 2, 2013 9:30 AM - 11:40 AM

Granzier, Henk | University of Arizona | July 2, 2013 9:30 AM - 11:40 AM

Greenberg, Barry | University of California, San Diego | July 3, 2013 8:30 AM - 10:40 AM

Halestrap, Andrew | University of Bristol | July 2, 2013 9:30 AM - 11:40 AM

Harding, Sian | Imperial College London | July 2, 2013 9:30 AM - 11:40 AM

Harris, Samantha | University of Arizona | July 1, 2013 2:00 PM - 4:10 PM

Hausenloy, Derek | University College London | July 4, 2013 9:30 AM - 11:30 AM

Hébert, Terence | McGill University | July 3, 2013 8:30 AM - 10:40 AM

Heusch, Gerd | University of Essen Medical School | July 1, 2013 2:00 PM - 4:10 PM

Hill, Joseph | UT Southwestern Medical Center | July 2, 2013 9:30 AM - 11:40 AM

Hirsch, Emilio | University of Torino | July 3, 2013 8:30 AM - 10:40 AM

Hool, Livia | The University of Western Australia | July 3, 2013 3:00 PM - 5:00 PM

Hori, Matsatsugu | Osaka Medical Center for Cancer and Cardiovascular Diseases | July 1, 2013 10:00 AM - 12:00 PM

Houser, Steven | Temple University School of Medicine | July 3, 2013 8:30 AM - 10:40 AM

Insel, Paul | University of California, San Diego | July 3, 2013 3:00 PM - 5:00 PM

Jahns, Roland | University Hospital Würzburg | July 2, 2013 1:30 PM - 3:30 PM

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Invited Speakers

Ju, Yue-kun | University of Sydney | July 1, 2013 10:00 AM - 12:00 PM

Kamp, Timothy | University of Wisconsin | July 3, 2013 3:00 PM - 5:00 PM

Kelly, Daniel | Sanford-Burnham Medical Research Institute | July 3, 2013 3:00 PM - 5:00 PM

Khakoo, Aarif | Amgen Inc. | July 4, 2013 9:30 AM - 11:30 AM

Kirshenbaum, Lorrie | University of Manitoba | July 2, 2013 1:30 PM - 3:30 PM

Kloner, Robert | Keck School of Medicine, USC, Heart Inst Good Samaritan Hospital | July 2, 2013 9:30 AM - 11:40 AM

Knollmann, Bjorn | Vanderbilt University | July 1, 2013 10:00 AM - 12:00 PM

Koch, Walter | Temple University | July 3, 2013 8:30 AM - 10:40 AM

Komuro, Issei | The University of Tokyo | July 2, 2013 1:30 PM - 3:30 PM

Kontrogianni-Konstantopoulos, Aikaterini | University of Maryland School of Medicine | July 2, 2013 9:30 AM - 11:40 AM

Kranias, Evangelia | University of Cincinnati College of Medicine | July 2, 2013 1:30 PM - 3:30 PM

Lakatta, Edward | National Institute on Aging Intramural Research Program, NIH | July 1, 2013 10:00 AM - 12:00 PM

Lamas, Santiago | Centro de Biologia Molecular Severo Ochoa (CSIC-UAM) | July 3, 2013 8:30 AM - 10:40 AM

Laver, Derek | University of Newcastle | July 4, 2013 9:30 AM - 11:30 AM

Lecour, Sandrine | Hatter, Institute, University of Cape Town, South Africa | July 4, 2013 9:30 AM - 11:30 AM

Lefer, David | Emory University School of Medicine | July 3, 2013 3:00 PM - 5:00 PM

Lei, Ming | University of Manchester | July 1, 2013 10:00 AM - 12:00 PM

Leinwand, Leslie | University of Colorado | July 4, 2013 9:30 AM - 11:30 AM

Levy, Finn Olav | University of Oslo | July 3, 2013 8:30 AM - 10:40 AM

Lewandowski, E. Douglas | University of Illinois at Chicago College of Medicine | July 2, 2013 1:30 PM - 3:30 PM

Liao, Ronglih | Brigham & Women's Hospital, Harvard Medical School | July 1, 2013 10:00 AM - 12:00 PM

Linke, Linke | Ruhr University Bochum | July 2, 2013 9:30 AM - 11:40 AM

Lohse, Martin | University of Würzburg, Institute of Pharmacology and Toxicology | July 2, 2013 9:30 AM - 11:40 AM

London, Barry | University of Iowa | July 1, 2013 10:00 AM - 12:00 PM

Lopaschuk, Gary | University of Alberta | July 2, 2013 1:30 PM - 3:30 PM

Maier, Lars | University Goettingen | July 2, 2013 9:30 AM - 11:40 AM

Malhotra, Atul | Harvard Medical School | July 3, 2013 8:30 AM - 10:40 AM

Mann, Douglas | Washington University School of Medicine | July 2, 2013 1:30 PM - 3:30 PM

Marban, Eduardo | Cedars-Sinai Heart Institute | July 2, 2013 1:30 PM - 3:30 PM

Mattiazzi, Alicia | Centro de Investigaciones Cardiovasculares | July 1, 2013 2:00 PM - 4:10 PM

Mayr, Manuel | King's College London | July 1, 2013 10:00 AM - 12:00 PM

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Invited Speakers

McKinsey, Timothy | University of Colorado Denver | July 2, 2013 9:30 AM - 11:40 AM

McMullen, Julie | Baker IDI Heart and Diabetes Institute | July 1, 2013 10:00 AM - 12:00 PM

Mercola, Mark | Sanford Burnham Medical Research Institute, San Diego | July 4, 2013 9:30 AM - 11:30 AM

Metzger, Joseph | University of Minnesota | July 1, 2013 10:00 AM - 12:00 PM

Michel, Thomas | Brigham and Women's Hospital, Harvard Medical School | July 3, 2013 3:00 PM - 5:00 PM

Mochly-Rosen, Daria | Stanford University School of Medicine | July 4, 2013 9:30 AM - 11:30 AM

Mongillo, Marco | University of Padova | July 3, 2013 3:00 PM - 5:00 PM

Motterlini, Roberto | INSERM | July 1, 2013 2:00 PM - 4:10 PM

Mundiña-Weilemann, Cecilia | Centro de Investigaciones Cardiovasculares | July 4, 2013 9:30 AM - 11:30 AM

Murphy, Elizabeth | National Heart, Lung, and Blood Institute, NIH | July 1, 2013 2:00 PM - 4:10 PM

Murry, Chuck | University of Washington | July 2, 2013 9:30 AM - 11:40 AM

Offermanns, Stefan | Max-Planck-Institute for Heart and Lung Research | July 3, 2013 8:30 AM - 10:40 AM

Olson, Eric | UT Southwestern Medical Center | July 1, 2013 10:00 AM - 12:00 PM

O'Rourke, Brian | Johns Hopkins University | July 2, 2013 1:30 PM - 3:30 PM

Otsu, Kinya | King's College London | July 1, 2013 10:00 AM - 12:00 PM

Ovize, Michel | Hospices Civils de Lyon | July 2, 2013 9:30 AM - 11:40 AM

Palomeque, Julieta | Centro de Investigaciones Cardiovasculares | July 4, 2013 9:30 AM - 11:30 AM

Patel, Hamel | University of California, San Diego | July 1, 2013 2:00 PM - 4:10 PM

Pepe, Salvatore | University of Melbourne & Murdoch Childrens Research Institute | July 2, 2013 1:30 PM - 3:30 PM

Ping, Peipei | UCLA David Geffen School of Medicine | July 3, 2013 8:30 AM - 10:40 AM

Porrello, Enzo | The University of Queensland | July 3, 2013 3:00 PM - 5:00 PM

Puceat, Michel | INSERM | July 1, 2013 10:00 AM - 12:00 PM

Qu, Zhilin | University of California, Los Angeles | July 2, 2013 1:30 PM - 3:30 PM

Ripplinger, Crystal | University of California, Davis | July 2, 2013 1:30 PM - 3:30 PM

Robbins, Jeff | Cincinnati Children's Hospital Medical Center | July 1, 2013 2:00 PM - 4:10 PM

Rockman, Howard | Duke University | July 2, 2013 9:30 AM - 11:40 AM

Sadoshima, Junichi | University of Medicine and Dentistry, New Jersey | July 1, 2013 2:00 PM - 4:10 PM

Saint, David | University of Adelaide | July 3, 2013 3:00 PM - 5:00 PM

Salama, Guy | University of Pittsburgh | July 3, 2013 3:00 PM - 5:00 PM

Sawyer, Douglas | Vanderbilt University | July 3, 2013 8:30 AM - 10:40 AM

Schulz, Rainer | Institute of Physiology, Justus-Liebig University of Giessen | July 4, 2013 9:30 AM - 11:30 AM

Shah, Ajay | King's College London | July 3, 2013 8:30 AM - 10:40 AM

Shaw, Robin | University of California, San Francisco | July 2, 2013 1:30 PM - 3:30 PM

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Invited Speakers

Shimokawa, Hiroaki | Tohoku University Graduate School of Medicine | July 3, 2013 8:30 AM - 10:40 AM

Shiva, Sruti | University of Pittsburgh | July 1, 2013 2:00 PM - 4:10 PM

Shivkumar, Kalyanam | University of California, Los Angeles | July 2, 2013 1:30 PM - 3:30 PM

Soeller, Christian | University of Auckland & University of Exeter | July 3, 2013 3:00 PM - 5:00 PM

Sperling, Silke | Experimental and Clinical Research Center, Charité | July 1, 2013 2:00 PM - 4:10 PM

Steenbergen, Charles | Johns Hopkins University | July 2, 2013 9:30 AM - 11:40 AM

Steinberg, Susan | Columbia University | July 1, 2013 10:00 AM - 12:00 PM

Sussman, Mark | San Diego State University | July 1, 2013 10:00 AM - 12:00 PM

Taegtmeyer, Heinrich | The University of Texas Medical School at Houston | July 2, 2013 1:30 PM - 3:30 PM

Tardiff, Jil | University of Arizona | July 1, 2013 10:00 AM - 12:00 PM

Thum, Thomas | Medical School Hannover | July 1, 2013 10:00 AM - 12:00 PM

Tian, Rong | University of Washington | July 3, 2013 3:00 PM - 5:00 PM

Valdivia, Hector | University of Michigan | July 1, 2013 2:00 PM - 4:10 PM

Van der Velden, Jolanda | Vanderbilt University Medical Center | July 1, 2013 2:00 PM - 4:10 PM

Van Eyk, Jennifer | Johns Hopkins University | July 3, 2013 8:30 AM - 10:40 AM

Vila-Petroff, Martín | Centro de Investigaciones Cardiovasculares | July 1, 2013 2:00 PM - 4:10 PM

Villarreal, Francisco | University of California, San Diego | July 1, 2013 2:00 PM - 4:10 PM

Vondriska, Thomas | University of California, Los Angeles | July 3, 2013 8:30 AM - 10:40 AM

Wakabayashi, Shigeo | National Cerebral and Cardiovascular Center Research Institute | July 3, 2013 8:30 AM - 10:40 AM

Walsh, Kenneth | Boston University | July 3, 2013 8:30 AM - 10:40 AM

Wang, Da-Zhi | Boston Children's Hospital, Harvard Medical School | July 1, 2013 10:00 AM - 12:00 PM

Wang, Qing | Huazhong University of Science and Technology/Cleveland Clinic | July 1, 2013 2:00 PM - 4:10 PM

Wang, Yibin | David Geffen School of Medicine, UCLA | July 2, 2013 1:30 PM - 3:30 PM

Weiss, James | University of California, Los Angeles | July 2, 2013 1:30 PM - 3:30 PM

Wu, Joseph | Stanford University School of Medicine | July 4, 2013 9:30 AM - 11:30 AM

Wu, Sean | Stanford University School of Medicine | July 4, 2013 9:30 AM - 11:30 AM

Xiang, Yang | University of California, Davis | July 2, 2013 1:30 PM - 3:30 PM

Xiao, Rui-Ping | Peking University | July 4, 2013 9:30 AM - 11:30 AM

Xu, Ming | Peking University Third Hospital | July 4, 2013 9:30 AM - 11:30 AM

Yang, Huangtian | Institute of Health Sciences | July 4, 2013 9:30 AM - 11:30 AM

Zaccolo, Manuela | University of Oxford | July 2, 2013 1:30 PM - 3:30 PM

Zhang, Jianyi | University of Minnesota | July 3, 2013 3:00 PM - 5:00 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First NameISHR Section Category

PS1-P1 Crossman David Australasian Calcium and Contractile FunctionPS1-P2 Hool Livia Australasian Calcium and Contractile FunctionPS1-P3 Hool Livia Australasian Calcium and Contractile FunctionPS1-P4 Dou Dou Chinese Calcium and Contractile FunctionPS1-P5 Flenner Frederik European Calcium and Contractile FunctionPS1-P6 White Christopher European Calcium and Contractile FunctionPS1-P7 Kusakari Yoichiro Japanese Calcium and Contractile FunctionPS1-P8 Sommese Leandro Latin American Calcium and Contractile FunctionPS1-P9 Gonzalez-Serrano Pilar North American Calcium and Contractile FunctionPS1-P10 Parks Randi North American Calcium and Contractile FunctionPS1-P11 Arnolda Leonard Australasian Cardiac RemodelingPS1-P12 Gao Xiao-Ming Australasian Cardiac RemodelingPS1-P13 Tsoutsman Tatiana Australasian Cardiac RemodelingPS1-P14 Wang Shijun Chinese Cardiac RemodelingPS1-P15 Tate Mitchel European Cardiac RemodelingPS1-P16 Khatib Said Younes European Cardiac RemodelingPS1-P17 Baysa Anton European Cardiac RemodelingPS1-P18 Yano Masamichi Japanese Cardiac RemodelingPS1-P19 Pérez-Treviño Perla Latin American Cardiac RemodelingPS1-P20 Nakama Karina Non-ISHR Member Cardiac RemodelingPS1-P21 Lange Stephan North American Cardiac RemodelingPS1-P22 Bagchi Rushita North American Cardiac RemodelingPS1-P23 Yang Yanfei North American Cardiac RemodelingPS1-P24 Egom Emmanuel North American Cardiac RemodelingPS1-P25 Kolpakov Mikhail North American Cardiac RemodelingPS1-P26 Fan Frank (Xiaohu) North American Cardiac RemodelingPS1-P27 Bell James Australasian CardioprotectionPS1-P28 Vella Rebecca Australasian CardioprotectionPS1-P29 Khong Fay Lin Australasian CardioprotectionPS1-P30 Tian FuJu Chinese CardioprotectionPS1-P31 Liu Xin Chinese CardioprotectionPS1-P32 Li Yuzhen Chinese CardioprotectionPS1-P33 Liu Xiuhua Chinese CardioprotectionPS1-P34 Wang Xiaoreng Chinese CardioprotectionPS1-P35 Bilginoğlu Ayça European CardioprotectionPS1-P36 Teh Elaine European CardioprotectionPS1-P37 Santer David European CardioprotectionPS1-P38 Leslie Robert European CardioprotectionPS1-P39 Fauconnier Jérémy European CardioprotectionPS1-P40 Bencsik Peter European CardioprotectionPS1-P41 Giricz Zoltan European CardioprotectionPS1-P42 Shainberg Asher European CardioprotectionPS1-P43 Das Saswati Indian CardioprotectionPS1-P44 Annapoorani Ponnambalam Indian CardioprotectionPS1-P45 Endo Jin Japanese CardioprotectionPS1-P46 Goulart Jair Latin American CardioprotectionPS1-P47 Carrasco Rodrigo Latin American CardioprotectionPS1-P48 Biswas Aviroop Non-ISHR Member CardioprotectionPS1-P49 Gray Charlie Non-ISHR Member CardioprotectionPS1-P50 Gupta Sudhiranjan North American CardioprotectionPS1-P51 Rainer Peter North American CardioprotectionPS1-P52 Jahania Salik North American Cardioprotection

Poster Session 1 (PS1): Monday, July 1, 2013 12:00 PM - 2:00 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First NameISHR Section Category

PS1-P53 Miyamoto Shigeki North American CardioprotectionPS1-P54 Gross Eric North American CardioprotectionPS1-P55 Menazza Sara North American CardioprotectionPS1-P56 Nguyen Tiffany Tuyen North American CardioprotectionPS1-P57 Govindapillai Arun North American CardioprotectionPS1-P58 Arnolda Leonard Australasian Excitability and PacemakersPS1-P59 Ge Fu Gui Chinese Excitability and PacemakersPS1-P60 Shen Lin-Lin Chinese Excitability and PacemakersPS1-P61 Zaglia Tania European Excitability and PacemakersPS1-P62 Bassani Rosana Latin American Excitability and PacemakersPS1-P63 Bassani José Latin American Excitability and PacemakersPS1-P64 Fang Lu Australasian Heart FailurePS1-P65 Mellor Kimberley Australasian Heart FailurePS1-P66 Walweel Kafa Australasian Heart FailurePS1-P67 Xu Ming Chinese Heart FailurePS1-P68 Sabourin Jessica European Heart FailurePS1-P69 Singh Sonia European Heart FailurePS1-P70 Castaldi Alessandra European Heart FailurePS1-P71 Yarham Janet European Heart FailurePS1-P72 Saikia Uma Nahar Indian Heart FailurePS1-P73 Khullar Madhu Indian Heart FailurePS1-P74 Tajiri Kazuko Japanese Heart FailurePS1-P75 Enomoto Hirokazu Japanese Heart FailurePS1-P76 Dohi Yoshihiro Japanese Heart FailurePS1-P77 Fukushima Arata Japanese Heart FailurePS1-P78 Hammer Karin Non-ISHR Member Heart FailurePS1-P79 Zordoky Beshay Non-ISHR Member Heart FailurePS1-P80 Bino Lucia Non-ISHR Member Heart FailurePS1-P81 Lim Byung-Kwan Non-ISHR Member Heart FailurePS1-P82 Rowell Janelle North American Heart FailurePS1-P83 Yang Yi North American Heart FailurePS1-P84 Pereira Laetitia North American Heart FailurePS1-P85 Herren Anthony North American Heart FailurePS1-P86 Al-Khoury Johny North American Heart FailurePS1-P87 Sucharov Carmen North American Heart FailurePS1-P88 Yang Xiangsheng North American Heart FailurePS1-P89 Blant Alexandra North American Heart FailurePS1-P90 Suarez Jorge North American Heart FailurePS1-P91 Diaz Juarez Julieta North American Heart FailurePS1-P92 Silva-Platas Christian North American Heart FailurePS1-P93 Guerrero-Beltrán Carlos Enrique North American Heart FailurePS1-P94 Figtree Gemma Australasian Oxidative Stress and NOPS1-P95 Dong Li-Hua Chinese Oxidative Stress and NOPS1-P96 Varga Zoltán European Oxidative Stress and NOPS1-P97 G S Ajith Kumar Indian Oxidative Stress and NOPS1-P98 Orban Marek Non-ISHR Member Oxidative Stress and NOPS1-P99 Al-Khoury Johny North American Oxidative Stress and NOPS1-P100 Vagnozzi Ronald North American Oxidative Stress and NOPS1-P101 Reichelt Melissa Australasian Signal TransductionPS1-P102 Rose'Meyer Roselyn Australasian Signal TransductionPS1-P103 Zhang Haifeng Chinese Signal TransductionPS1-P104 Sun Shaoguang Chinese Signal Transduction

Poster Session 1 (PS1): Monday, July 1, 2013 12:00 PM - 2:00 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First NameISHR Section Category

PS1-P105 Shang Dandan Chinese Signal TransductionPS1-P106 Ranieri Antonella European Signal TransductionPS1-P107 Markou Thomais European Signal TransductionPS1-P108 Loonat Aminah European Signal TransductionPS1-P109 Madonna Rosalinda European Signal TransductionPS1-P110 Kho Ay Lin European Signal TransductionPS1-P111 Francois Asvi European Signal TransductionPS1-P112 Sumida Tomokazu Japanese Signal TransductionPS1-P113 Shimizu Ippei Japanese Signal TransductionPS1-P114 Orlowski Alejandro Latin American Signal TransductionPS1-P115 Díaz Romina Latin American Signal TransductionPS1-P116 Yeves Alejandra Latin American Signal TransductionPS1-P117 Wilsbacher Lisa North American Signal TransductionPS1-P118 Fliegel Larry North American Signal TransductionPS1-P119 Morales Jose A. North American Signal TransductionPS1-P120 Xiang Sunny North American Signal TransductionPS1-P121 Li Jinliang North American Signal TransductionPS1-P122 Kirshenbaum Lorrie North American Signal TransductionPS1-P123 Pugach Emily North American Signal TransductionPS1-P124 Wang Yan Chinese Stem CellsPS1-P125 Che Hui Chinese Stem CellsPS1-P126 Navratilova Jana Non-ISHR Member Stem CellsPS1-P127 Blusztajn Agnieszka Non-ISHR Member Stem CellsPS1-P128 Valle Ileana Non-ISHR Member Stem CellsPS1-P129 MacArthur John Non-ISHR Member Stem CellsPS1-P130 Zhao Li-Mei Chinese Target and Drug DiscoveryPS1-P131 Liping Han Chinese Target and Drug DiscoveryPS1-P132 LI ZHichao Chinese Target and Drug DiscoveryPS1-P133 Li Zhichao Chinese Target and Drug DiscoveryPS1-P134 Hirt Marc European Target and Drug DiscoveryPS1-P135 Kijima Yoshiyuki Japanese Target and Drug DiscoveryPS1-P136 Gutiérrez-Salmeán Gabriela Latin American Target and Drug DiscoveryPS1-P137 Bailly Jacques Non-ISHR Member Target and Drug Discovery

Poster Session 1 (PS1): Monday, July 1, 2013 12:00 PM - 2:00 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First Name ISHR Section CategoryPS2-P1 Viola Helena Australasian Calcium and Contractile FunctionPS2-P2 Viola Helena Australasian Calcium and Contractile FunctionPS2-P3 Zhao Wen Chinese Calcium and Contractile FunctionPS2-P4 Yadid Moran European Calcium and Contractile FunctionPS2-P5 Messer Andrew European Calcium and Contractile FunctionPS2-P6 Shimizu Juichiro Japanese Calcium and Contractile FunctionPS2-P7 Salazar Ayleen Latin American Calcium and Contractile FunctionPS2-P8 Najibeddine Wassim North American Calcium and Contractile FunctionPS2-P9 Lam Chi Keung North American Calcium and Contractile FunctionPS2-P10 Edwards Andrew North American Calcium and Contractile FunctionPS2-P11 Ritchie Rebecca Australasian Cardiac RemodelingPS2-P12 SHAN Zhi Xin Chinese Cardiac RemodelingPS2-P13 Richardson Rachel European Cardiac RemodelingPS2-P14 Galatou Eleftheria European Cardiac RemodelingPS2-P15 Barallobre-Barreiro Javier European Cardiac RemodelingPS2-P16 Najafi Aref European Cardiac RemodelingPS2-P17 Vellaichamy Elangovan Indian Cardiac RemodelingPS2-P18 Kmit Fernanda Vieira Non-ISHR Member Cardiac RemodelingPS2-P19 Rachmin Inbal Non-ISHR Member Cardiac RemodelingPS2-P20 Santer David Non-ISHR Member Cardiac RemodelingPS2-P21 Roche Patricia North American Cardiac RemodelingPS2-P22 Danziger Robert North American Cardiac RemodelingPS2-P23 Abdelaziz Iman North American Cardiac RemodelingPS2-P24 Alemrayat Bayan North American Cardiac RemodelingPS2-P25 Davis, 3rd Robert North American Cardiac RemodelingPS2-P26 Kim Maengjo North American Cardiac RemodelingPS2-P27 Lee Ling North American Cardiac RemodelingPS2-P28 Thomas Colleen Australasian CardioprotectionPS2-P29 Alexa Andrei Australasian CardioprotectionPS2-P30 Liaw Norman Australasian CardioprotectionPS2-P31 Zhou Xiao Chinese CardioprotectionPS2-P32 Chen Chen Chinese CardioprotectionPS2-P33 He Yonggui Chinese CardioprotectionPS2-P34 Cao Chun-Mei Chinese CardioprotectionPS2-P35 gao ling Chinese CardioprotectionPS2-P36 Hochhauser Edith European CardioprotectionPS2-P37 Frias Miguel European CardioprotectionPS2-P38 Helgeland Erik European CardioprotectionPS2-P39 Aldugman Mohammed European CardioprotectionPS2-P40 Kessler-Icekson Gania European CardioprotectionPS2-P41 Kessler-Icekson Gania European CardioprotectionPS2-P42 Carnicka Slavka European CardioprotectionPS2-P43 Ledvenyiova Veronika European CardioprotectionPS2-P44 Ikeda Gentaro Japanese CardioprotectionPS2-P45 Nakano Yasuhiro Japanese CardioprotectionPS2-P46 Nagaoka Kazuhiro Japanese CardioprotectionPS2-P47 Donoso Paulina Latin American CardioprotectionPS2-P48 Castil lo Rodrigo Latin American CardioprotectionPS2-P49 Webster Ingrid Non-ISHR Member CardioprotectionPS2-P50 Webster Ingrid Non-ISHR Member CardioprotectionPS2-P51 Egar Jeanne North American CardioprotectionPS2-P52 Ganguly Riya North American Cardioprotection

Poster Session 2 (PS2): Tuesday, July 2, 2013 11:40 AM - 1:30 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First Name ISHR Section CategoryPS2-P53 Zong Nobel North American CardioprotectionPS2-P54 Lam Maggie PY North American CardioprotectionPS2-P55 Kim Sujeoung North American CardioprotectionPS2-P56 Lin Amanda North American CardioprotectionPS2-P57 Zong Nobel North American CardioprotectionPS2-P58 Yaniv Yael Non-ISHR Member Excitability and PacemakersPS2-P59 Yaniv Yael Non-ISHR Member Excitability and PacemakersPS2-P60 Xie Yuanfang North American Excitability and PacemakersPS2-P61 Clements-Jewery Hugh North American Excitability and PacemakersPS2-P62 Kalyanasundaram Anuradha North American Excitability and PacemakersPS2-P63 Torrente Angelo North American Excitability and PacemakersPS2-P64 Bernardo Bianca Australasian Heart FailurePS2-P65 Cao Nga Australasian Heart FailurePS2-P66 Zhang Weihua Chinese Heart FailurePS2-P67 Su Min Chinese Heart FailurePS2-P68 Ehler Elisabeth European Heart FailurePS2-P69 Stenzig Justus European Heart FailurePS2-P70 Wang Xinzhu European Heart FailurePS2-P71 Ricke-Hoch Melanie European Heart FailurePS2-P72 Stapel Britta European Heart FailurePS2-P73 Hochhauser Edith European Heart FailurePS2-P74 MIttal Anupam Indian Heart FailurePS2-P75 Kubota Akihiko Japanese Heart FailurePS2-P76 Fujiu Katsuhito Japanese Heart FailurePS2-P77 Okada Katsuki Japanese Heart FailurePS2-P78 Higo Tomoaki Japanese Heart FailurePS2-P79 Teng Allen CT North American Heart FailurePS2-P80 Abbasi Cynthia North American Heart FailurePS2-P81 Cosme Jake North American Heart FailurePS2-P82 Wang Dingyan North American Heart FailurePS2-P83 Methawasin Mei North American Heart FailurePS2-P84 van Dijk Sabine North American Heart FailurePS2-P85 Keita Ramatoulaye North American Heart FailurePS2-P86 Carley Andrew North American Heart FailurePS2-P87 Lahey Ryan North American Heart FailurePS2-P88 Mishra Shikha North American Heart FailurePS2-P89 Ahuja Preeti North American Heart FailurePS2-P90 Tsoporis James North American Heart FailurePS2-P91 Setty Shaun North American Heart FailurePS2-P92 Chan X'avia North American Heart FailurePS2-P93 Pyle W. Glen North American Heart FailurePS2-P94 Muralidharan Padmapriya Australasian Oxidative Stress and NOPS2-P95 Xia Xiaohong Chinese Oxidative Stress and NOPS2-P96 Cheang Wai San Chinese Oxidative Stress and NOPS2-P97 Miriyala Sumitra Indian Oxidative Stress and NOPS2-P98 Gonano Luis Latin American Oxidative Stress and NOPS2-P99 Mowafy Hatem Hossam Non-ISHR Member Oxidative Stress and NOPS2-P100 Feridooni Tiam North American Oxidative Stress and NOPS2-P101 Woodcock Elizabeth Australasian Signal TransductionPS2-P102 Xiao Han Chinese Signal TransductionPS2-P103 Zhang Lijun Chinese Signal TransductionPS2-P104 Qi Ying-Xin Chinese Signal Transduction

Poster Session 2 (PS2): Tuesday, July 2, 2013 11:40 AM - 1:30 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First Name ISHR Section CategoryPS2-P105 Ghigo Alessandra European Signal TransductionPS2-P106 Jabr Rita European Signal TransductionPS2-P107 Melsom Caroline European Signal TransductionPS2-P108 Lezoualc'h Frank European Signal TransductionPS2-P109 Bassi Rekha European Signal TransductionPS2-P110 Arabacilar Pelin European Signal TransductionPS2-P111 Smith Emma European Signal TransductionPS2-P112 Arita Yoh Japanese Signal TransductionPS2-P113 O-Uchi Jin Japanese Signal TransductionPS2-P114 Pedrozo Zully Rocio Latin American Signal TransductionPS2-P115 Palomeque Julieta Latin American Signal TransductionPS2-P116 Sankar Natesan North American Signal TransductionPS2-P117 Hotchkiss Adam North American Signal TransductionPS2-P118 Moreno Aldo North American Signal TransductionPS2-P119 Gupta Manish North American Signal TransductionPS2-P120 Greenwald Eric North American Signal TransductionPS2-P121 Polanowska-Grabowska Renata North American Signal TransductionPS2-P122 Monasky Michelle North American Signal TransductionPS2-P123 Lim Shiang Yong Australasian Stem CellsPS2-P124 Lim Shiang Yong Australasian Stem CellsPS2-P125 Yu Xi-Yong Chinese Stem CellsPS2-P126 Madonna Rosalinda European Stem CellsPS2-P127 Egashira Toru Japanese Stem CellsPS2-P128 LeBlanc Amanda North American Stem CellsPS2-P129 Willems Erik North American Stem CellsPS2-P130 Cai Wenqing North American Stem CellsPS2-P131 Wu Liling Chinese Target and Drug DiscoveryPS2-P132 Liang Xiangyan Chinese Target and Drug DiscoveryPS2-P133 Bisserierb Malik European Target and Drug DiscoveryPS2-P134 Yabumoto Chizuru Japanese Target and Drug DiscoveryPS2-P135 Takeda Yukiji Japanese Target and Drug DiscoveryPS2-P136 Lim Byung-Kwan Non-ISHR Member Target and Drug Discovery

Poster Session 2 (PS2): Tuesday, July 2, 2013 11:40 AM - 1:30 PM

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44

Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First Name ISHR Section CategoryPS3-P1 Hou Yufeng Australasian Calcium and Contractile FunctionPS3-P2 Deng Chunyu Chinese Calcium and Contractile FunctionPS3-P3 Adameova Adriana European Calcium and Contractile FunctionPS3-P4 Marston Steven European Calcium and Contractile FunctionPS3-P5 Ziegelhoffer Attila European Calcium and Contractile FunctionPS3-P6 Oshiyama Natália Latin American Calcium and Contractile FunctionPS3-P7 Valverde Carlos Latin American Calcium and Contractile FunctionPS3-P8 Capes E. Michelle North American Calcium and Contractile FunctionPS3-P9 Robia Seth North American Calcium and Contractile FunctionPS3-P10 Kooij Viola North American Calcium and Contractile FunctionPS3-P11 Zhu Guangjin Chinese Cardiac RemodelingPS3-P12 Robinson Emma European Cardiac RemodelingPS3-P13 Santer David European Cardiac RemodelingPS3-P14 Lencova-Popelova Olga European Cardiac RemodelingPS3-P15 Terracciano Cesare European Cardiac RemodelingPS3-P16 Katsumata Yoshinori Japanese Cardiac RemodelingPS3-P17 Nakamura Ryo Japanese Cardiac RemodelingPS3-P18 Touma Marlin Non-ISHR Member Cardiac RemodelingPS3-P19 Kooij Viola North American Cardiac RemodelingPS3-P20 Yang Xiangsheng North American Cardiac RemodelingPS3-P21 Domenighetti Andrea North American Cardiac RemodelingPS3-P22 Gupta Sudhiranjan North American Cardiac RemodelingPS3-P23 Passariello Catherine North American Cardiac RemodelingPS3-P24 MacLean Jessica North American Cardiac RemodelingPS3-P25 Qu Jun North American Cardiac RemodelingPS3-P26 Ramirez-Sanchez Israel North American Cardiac RemodelingPS3-P27 Gao Chen North American Cardiac RemodelingPS3-P28 Qi Ying Xin Chinese Cardiac RemodelingPS3-P29 Tsuruda Toshihiro Japanese Cardiac RemodelingPS3-P30 Liaw Norman Australasian CardioprotectionPS3-P31 Qin CX Australasian CardioprotectionPS3-P32 Yang Huang-Tian Chinese CardioprotectionPS3-P33 Zhou Ping Chinese CardioprotectionPS3-P34 Cai Ting Shi Chinese CardioprotectionPS3-P35 Tie Ru Chinese CardioprotectionPS3-P36 Zhao Yajun Chinese CardioprotectionPS3-P37 Ravingerova Tanya European CardioprotectionPS3-P38 Sterba Martin European CardioprotectionPS3-P39 Simunek Tomas European CardioprotectionPS3-P40 Sklyanna Olena European CardioprotectionPS3-P41 Gönczi Márton European CardioprotectionPS3-P42 Robertson-Gray Olivia European CardioprotectionPS3-P43 Ferko Miroslav European CardioprotectionPS3-P44 Muráriková Martina European CardioprotectionPS3-P45 Nonaka Daishi Japanese CardioprotectionPS3-P46 Narumi Taro Japanese CardioprotectionPS3-P47 Nakamura-NIshitani Tomoe Japanese CardioprotectionPS3-P48 Hernández-Reséndiz Sauri Latin American CardioprotectionPS3-P49 Salie Ruduwaan Non-ISHR Member CardioprotectionPS3-P50 Rockwood Kenneth Non-ISHR Member CardioprotectionPS3-P51 Soetkamp Daniel Non-ISHR Member CardioprotectionPS3-P52 Bhuiyan Md. Shenuarin North American Cardioprotection

Poster Session 3 (PS3): Wednesday, July 3, 2013 1:10 PM - 3:00 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First Name ISHR Section CategoryPS3-P53 Fan Frank (Xiaohu) North American CardioprotectionPS3-P54 Seubert John North American CardioprotectionPS3-P55 Alsaleh Nasser North American CardioprotectionPS3-P56 Tranter Michael North American CardioprotectionPS3-P57 Ong Sang-Ging North American CardioprotectionPS3-P58 Lee Won Hee North American CardioprotectionPS3-P59 Larson Eric North American Excitability and PacemakersPS3-P60 St. Clair Joshua North American Excitability and PacemakersPS3-P61 Hua Rui North American Excitability and PacemakersPS3-P62 Vella Kimberly North American Excitability and PacemakersPS3-P63 Krishnaswamy Pooja North American Excitability and PacemakersPS3-P64 Sheng Xiao Ye North American Excitability and PacemakersPS3-P65 Golovko Vladimir European Excitability and PacemakersPS3-P66 Sheikh Farah North American Excitability and PacemakersPS3-P67 Munro Michelle Australasian Heart FailurePS3-P68 Bienvenu Laura Australasian Heart FailurePS3-P69 Xu Chang-Qing Chinese Heart FailurePS3-P70 Hamdani Nazha European Heart FailurePS3-P71 Schoemaker Regien European Heart FailurePS3-P72 Gouweleeuw Leonie European Heart FailurePS3-P73 Gouweleeuw Leonie European Heart FailurePS3-P74 Dargan James European Heart FailurePS3-P75 Walsh Sarah European Heart FailurePS3-P76 Singh Gurinder Indian Heart FailurePS3-P77 Mahapatra Nitish Indian Heart FailurePS3-P78 Uchinaka Ayako Japanese Heart FailurePS3-P79 Sakai Satoshi Japanese Heart FailurePS3-P80 Watanabe Tomoyuki Japanese Heart FailurePS3-P81 Toyo-oka Licht Japanese Heart FailurePS3-P82 Qu Jun North American Heart FailurePS3-P83 De Lange Willem North American Heart FailurePS3-P84 McLendon Patrick North American Heart FailurePS3-P85 Schroeder Analyne North American Heart FailurePS3-P86 Manso Ana Maria North American Heart FailurePS3-P87 Ryall Karen North American Heart FailurePS3-P88 Henze Marcus North American Heart FailurePS3-P89 Wilder 1 Tanganyika North American Heart FailurePS3-P90 Das Sam North American Heart FailurePS3-P91 Miyamoto Shelley North American Heart FailurePS3-P92 Nakano Stephanie North American Heart FailurePS3-P93 García-Rivas Gerardo North American Heart FailurePS3-P94 Agnetti Giulio North American Heart FailurePS3-P95 Sun Haipeng North American Heart FailurePS3-P96 Atluri Pavan North American Heart FailurePS3-P97 Toyo-oka Licht Japanese Heart FailurePS3-P98 Ritchie Rebecca Australasian Oxidative Stress and NOPS3-P99 Lu Fanghao Chinese Oxidative Stress and NOPS3-P100 Karunakaran Gauthaman European Oxidative Stress and NOPS3-P101 Karunakaran Gauthaman European Oxidative Stress and NOPS3-P102 Kisvári Gábor European Oxidative Stress and NOPS3-P103 Correa Francisco Latin American Oxidative Stress and NOPS3-P104 Uludag Orhan Non-ISHR Member Oxidative Stress and NO

Poster Session 3 (PS3): Wednesday, July 3, 2013 1:10 PM - 3:00 PM

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Poster Sessions and Numbers

Poster Session

& Number

Presenting Author

Last Name

Presenting Author

First Name ISHR Section CategoryPS3-P105 Kohr Mark North American Oxidative Stress and NOPS3-P106 Cooley Nicola Australasian Signal TransductionPS3-P107 Yin Lianhua Chinese Signal TransductionPS3-P108 Gong Kaizheng Chinese Signal TransductionPS3-P109 Plazzo Anna Pia European Signal TransductionPS3-P110 ROBIN Elodie European Signal TransductionPS3-P111 Marcillac Fabrice European Signal TransductionPS3-P112 Zaglia Tania European Signal TransductionPS3-P113 Zhang Qiuping European Signal TransductionPS3-P114 Panchatcharam Manikandan Indian Signal TransductionPS3-P115 Jhun Bong Sook Japanese Signal TransductionPS3-P116 Israeli Sharon Non-ISHR Member Signal TransductionPS3-P117 Bossuyt Julie North American Signal TransductionPS3-P118 Ferrero Maura North American Signal TransductionPS3-P119 Purcell Nicole North American Signal TransductionPS3-P120 Thistlethwaite Patricia North American Signal TransductionPS3-P121 Li Hao-Dong North American Signal TransductionPS3-P122 Ramirez-Sanchez Israel North American Signal TransductionPS3-P123 Fu Qin North American Signal TransductionPS3-P124 Shi Qian North American Signal TransductionPS3-P125 Estrada-Avilés Rafael North American Signal TransductionPS3-P126 Feng Yuliang Chinese Stem CellsPS3-P127 Song Yimeng Chinese Stem CellsPS3-P128 Micheu Miruna European Stem CellsPS3-P129 Michielin Federica European Stem CellsPS3-P130 Muraoka Naoto Japanese Stem CellsPS3-P131 Nomura Seitaro Japanese Stem CellsPS3-P132 Fair Joel North American Stem CellsPS3-P133 Wang Meijing North American Stem CellsPS3-P134 Gu Mingxia North American Stem CellsPS3-P135 Xu Shunjiang Chinese Target and Drug DiscoveryPS3-P136 Yang Liming Chinese Target and Drug DiscoveryPS3-P137 Haller Paul European Target and Drug DiscoveryPS3-P138 Ishimori Naoki Japanese Target and Drug DiscoveryPS3-P139 Moreno_Ulloa Aldo North American Target and Drug DiscoveryPS3-P140 Montgomery Megan North American Target and Drug DiscoveryPS3-P141 Warszta Dominik European Signal TransductionPS3-P142 Shishido Tetsuro Japanese Heart FailurePS3-P143 Campesan Marika European Oxidative Stress and NO

Poster Session 3 (PS3): Wednesday, July 3, 2013 1:10 PM - 3:00 PM

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47

Exhibitors

Company Name: ADInstruments Contact Name: Matthew Dilworth Contact Email Address: [email protected] Contact Phone: 719-576-3970 Company Address: 2205 Executive Circle, Colorado Springs, Colorado 80906 Website: http://www.adinstruments.com ADInstruments provides computer-based data acquisition systems for cardiovascular research applications. Our PowerLab data acquisition systems and LabChart software provide outstanding data acquisition, display, analysis for today's lab bench research scientist. Radnoti has been setting the research standard in glassware apparatus technology and functionality for over 35 years with complete solutions for isolated tissue and isolated organ research from tissue bath and myograph systems to isolated Langendorff, working heart systems, and isolated perfused organ systems.

Company Name: Multi Channel Systems Contact Name: Margaret Badon Contact Email Address: [email protected] Contact Phone: 631-393-6401 Company Address: 60 Marine Street, Farmingdale, New York 11735 Website: http://www.multichannelsystems.com Multi Channel Systems, with our partner ALA Scientific Instruments, have a long-standing experience in cardiac electrophysiology, safety pharmacology, and stem cell research. Our systems enable mapping and high-resolution recording of cardiac signals from individual cells, tissue and whole organs. We have high-resolution microelectrode arrays, cardiac specific software for QT analysis and high resolution cardiac mapping. We can record in vivo from beating hearts, as well as Langendorff preparations. Both in vivo and in vitro systems from basic to applied research are available.

Company Name: Harvard Apparatus Contact Name: Mary Ann Capone Contact Email Address: [email protected] Contact Phone: 508-893-8999 Company Address: 84 October Hill Road, Holliston, Massachusetts 01746 Website: http://www.harvardapparatus.com Hugo Sachs Elektronik – Harvard Apparatus Cardiovascular Physiology Workstations, including Langendorff and Working Heart Perfusion Systems, are at the heart of cardiovascular and physiology research. NEW bioreactors provide the perfect solution for cutting edge Regenerative Medicine research. Our systems are the preferred choice for Drug Discovery, Safety Pharmacology & Tissue Engineering.

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Company Name: IonOptix Contact Name: Joe Soughayer Email Address: [email protected] Work Phone: 617-696-7335 Company Address: 309 Hillside Street, Milton, Massachusetts 02186 Website: http://www.ionoptix.com IonOptix was formed in 1990 with the goal of developing systems for quantifying calcium using fluorescent indicators. A system was developed through academic collaborations to simultaneously record calcium levels and cell length from a single cardiomyocyte. A software-based edge-detection system was developed in 1995 and, in 1998, IonOptix developed real-time sarcomere length recording. IonOptix is now the leader in simultaneous quantitative calcium and contractility data acquisition. Our new force transducer can be added to measure fast nanoNewton forces from single intact myocytes. Other turnkey products include electrostimulation of myocytes in culture, blood vessel fluorimetry and diameter, and whole heart fluorescence.

Company Name: VisualSonics

Contact Name: Mandi Da Silva Contact Email Address: [email protected] Contact Phone: 416-484-5000 Company Address: 3080 Yonge Street Suite 6100, Toronto, Ontario M4N3N1 , Canada Website: http://www.visualsonics.com VisualSonics is the undisputed world leader in real-time, in vivo, high-resolution, micro-imaging systems, providing modalities specifically designed for preclinical research. These cutting edge technologies allow researchers at the world’s most prestigious pharmaceutical and biotechnology companies, hospitals and universities to conduct research in cardiovascular, cancer, neurobiology and developmental biology areas. These technologies support applications that include genetic research, phenotypic studies and drug development. VisualSonics platforms combine high-resolution, real-time in vivo imaging at reasonable cost with ease-of-use and quantifiable results.

Company Name: Seahorse Bioscience

Contact Email Address: [email protected] Contact Phone: 978-671-1600 Company Address: 16 Esquire Rd, North Billerica, MA 01862 Website: www.seahorsebio.com The Seahorse XFe Analyzer and stress test kits provide cellular bioenergetic scientists with an efficient and user-friendly method to non-invasively measure cell metabolism in cardiomyocytes, vascular endothelial cells, embryonic stem cells and more - providing information on basal oxygen consumption, glycolysis rates, ATP turnover, and respiratory capacity to assess mitochondrial dysfunction.

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Company Name: Fisher Scientific Contact Name: Jason B. Jaurequi Contact Email Address: [email protected] Contact Phone: 858-373-7238 Company Address: 300 Industry Dr., Pittsburgh, PA 15275 Website: http://www.fishersci.com Thermo Fisher Scientific is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of $13 billion, we have approximately 39,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through three premier brands, Thermo Scientific, Fisher Scientific and Unity™ Lab Services, which offer a unique combination of innovative technologies, convenient purchasing options and a single solution for laboratory operations management. Our products and services help our customers solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity.

Company Name: Eppendorf Contact Name: Christina Glennon-Czerwinski Contact Email Address: [email protected] Contact Phone: 760-801-1850 Company Address: 102 Motor Parkway, Hauppauge, NY 11788 Website: www.eppendorfna.com Eppendorf is a leading life science company that develops and sells instruments, consumables, and services for liquid-, sample-, and cell handling in laboratories worldwide. Its product range includes pipettes and automated pipetting systems, dispensers, centrifuges, mixers, spectrometers, and DNA amplification equipment as well as ultra-low temperature freezers, fermentors, bioreactors, CO2 incubators, shakers, and cell manipulation systems. Associated consumables like pipette tips, test tubes, microtiter plates, and disposable bioreactors complement the instruments for highest quality workflow solutions.

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NOTES

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NOTES