Bell Ringer (5)Bell Ringer (5)

What are the stages What are the stages of the cell cycle?of the cell cycle?

Bell RingerBell Ringer

Put these Put these pictures of pictures of mitosis in the mitosis in the correct order.correct order.Sketch them.Sketch them.Label each Label each phase.phase.

Mitosis FoldableMitosis FoldableMaterials: 3 pieces of white paperMaterials: 3 pieces of white paperStagger the pages about 1 inch apart.Stagger the pages about 1 inch apart.Fold the pages “hamburger style” to make Fold the pages “hamburger style” to make 6 flaps.6 flaps.Label the flaps as follows: (1) The Cell Label the flaps as follows: (1) The Cell Cycle & Mitosis (2) Interphase (3) Cycle & Mitosis (2) Interphase (3) Prophase (4) Metaphase (5) Anaphase (6) Prophase (4) Metaphase (5) Anaphase (6) Telophase & CytokinesisTelophase & CytokinesisOn the back, draw the cell cycle.On the back, draw the cell cycle.

G2 phase

S phase

G1 phase

M phase

The Cell CycleThe Cell Cycle

InterphaseInterphase (period in-between division) (period in-between division)– G1 (growth)G1 (growth)– S (DNA replication)S (DNA replication)– G2 (prepare for mitosis)G2 (prepare for mitosis)M phaseM phase (division) (division)– Mitosis (division of the nucleus)Mitosis (division of the nucleus)– Cytokinesis (division of the cytoplasm)Cytokinesis (division of the cytoplasm)Most of the time the cell is in Most of the time the cell is in interphaseinterphase!!!!!!

InterphaseInterphase

1.1. G1 (growth) G1 (growth) 2.2. S (DNA replication) S (DNA replication) 3.3. G2 (prepare for mitosis)G2 (prepare for mitosis)

www.youtube.com/watch?v=VlN7K1-9QB0

Mitosis & Cytokinesis!Mitosis & Cytokinesis!

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(a) (b)

(c)

mitoticcell

division

mitoticcell

division

Multicellular organisms grow, maintain and repair cells by mitosis.

Mitosis Facts

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ReplicationReplication

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DNA Doubles

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MitosisMitosisMitosis is the division of the Mitosis is the division of the nucleusnucleus..There are There are 4 stages 4 stages of mitosis:of mitosis:–Prophase Prophase –MetaphaseMetaphase–AnaphaseAnaphase–TelophaseTelophase

Terms CentrioleCentriole CentromereCentromere SpindleSpindle Chromosome Chromosome (sister (sister

chromatids)chromatids)

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ProphaseProphaseIn this stage everything sets up for In this stage everything sets up for mitosis. It is the first and mitosis. It is the first and longestlongest stage stage of mitosis.of mitosis.The The nucleolus disappears.nucleolus disappears.The The chromatin condenses into chromatin condenses into chromosomes.chromosomes.The The centrioles separatecentrioles separate and and form a form a spindlespindle of microtubules. of microtubules.The The nuclear membrane breaks down.nuclear membrane breaks down.

ProphaseProphase

centromeres

sister chromatids CLA

MetaphaseMetaphase

Metaphase is the 2Metaphase is the 2ndnd phase of mitosis. phase of mitosis.The The spindle attaches to the spindle attaches to the centromere centromere of the chromosomes.of the chromosomes.The chromosomes line up on the The chromosomes line up on the spindle in the MIDDLE of the cell.spindle in the MIDDLE of the cell.Metaphase may last only a few Metaphase may last only a few minutes.minutes.

MetaphaseMetaphase

AnaphaseAnaphaseAnaphase is the 3Anaphase is the 3rdrd phase of mitosis. phase of mitosis.In this phase the In this phase the chromosomes are chromosomes are pulled APART at the centromerepulled APART at the centromere..Sister chromatids are pulled to Sister chromatids are pulled to opposite ends of the cell.opposite ends of the cell.Anaphase begins as soon as the Anaphase begins as soon as the chromosomes begin separating and chromosomes begin separating and ends as soon as the chromosomes ends as soon as the chromosomes stop moving. stop moving.

AnaphaseAnaphase

TelophaseTelophase

This is the last phase of mitosis.This is the last phase of mitosis.ChromosomesChromosomes disperse and tangle disperse and tangle back into chromatinback into chromatin..2 2 nuclear envelopes formnuclear envelopes form around the around the chromatin.chromatin.The The spindle breaks downspindle breaks down..The The nucleolus becomes visiblenucleolus becomes visible..

TelophaseTelophase

CytokinesisCytokinesisCytokinesis is the division of the Cytokinesis is the division of the cytoplasmcytoplasm. . It usually It usually occurs at the same time as occurs at the same time as telophasetelophase..The cytoplasm can be divided 2 ways:The cytoplasm can be divided 2 ways:– Animal cells pinch offAnimal cells pinch off into 2 cells. into 2 cells.– Plant cells form aPlant cells form a cell platecell plate (which is (which is

the beginning of the cell wall)the beginning of the cell wall)

Cytokinesis Cytokinesis in in

Animal Animal CellsCells

Cytokinesis Cytokinesis in in

Plant Cells Plant Cells

Final ProductFinal Product

The final product of mitosis The final product of mitosis and cytokinesis is:and cytokinesis is:–2 genetically identical 2 genetically identical

daughter cellsdaughter cells

Mitosis - can youname the stages?

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