what can dna health test tell you? · healthy living and ageing? if your environment is problematic...
TRANSCRIPT
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Preventive health and wellness approach based on scientific evidence
What can DNA Health Test tell you?
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Overview
1. Our journey with you 2. Basic concepts 3. Risk assessment frameworks
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I’m frustrated with my ongoing
symptoms and not performing in my
daily life.
I NEED answers!
Our journey with you
The future of health care will be a world away from the current system that typically treats people only after they become sick.
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Our journey with you
Meeting of minds Research
2012
Launched 1st DNA Test Lifestyle Questionnaire Portal
2014
Practitioner Portal Best New Product award
2015
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Our journey with you
Report Generator Tool
Health and wellness DNA Test
2016
New look Reports Practitioner Support Notes
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Our journey with you
Risk for Coeliac Disease/Gluten sensitivity
Increased need for antioxidants
Risk for essential fatty acids imbalance
2017
Lifestyle Assessment
Report
PUFA levels influenced by diet and genetic availability
• FADS1: reduced D5D activity; impacts downstream
production of omega 3 precursors
• FADS2: increased D6D activity; impacts downstream
production of omega 6 precursors
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Our journey with you
CYP7A1 Response to cholesterol lowering functional foods
2018 Research and development
CYP7A1 genetic variant affects how well foods such as plant sterols and beta-glucan (found in many cholesterol-lowering functional food products) will reduce total cholesterol (TC) and Low-Density Lipoprotein cholesterol (LDL-C)
Why might this be useful to know? • How likely a nutritional protocol designed to optimise LDL-C levels using plant sterols may be
effective genetically. • Alongside this, G allele genetic variants of CYP7A1 may also be sensitive to increased TC and
LDL-C when including dairy in their diet.
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Our journey with you
32 and you evidence for genetic dental disorders
2018 Research and development
Sports Performance evidence for genetic variants and epigenetics
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Scientific process
Our scientific process to assess potential candidate SNPs
Relevance: Susceptibility genes need to be characterised by biological studies
Reliability: Scientific papers, research data and population
Actionable: Nutritional and lifestyle interventions
Lab testing
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Who are we working with
Nutritional Practitioners
Naturopaths Functional Medicine
Osteopaths GPs/Holistic Dentists
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myDNAhealth approach
The environment around us, our genetic inheritance, how we live our lives and the opportunities we have together largely determine our health.
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myDNAhealth approach
THE GREATEST HEALTH THREATS NOW ARISE FROM HOW WE LIVE, WORK, EAT, PLAY, AND MOVE
• NCDs can progress slowly in people and include type 2 diabetes, Alzheimer’s and Cardiovascular Disease …
• Non-communicable symptoms can be weight gain, tiredness, joint pain, low mood, gut health issues etc.
• Risk factors include environment, excessive weight gain, age, genetics, physical inactivity, smoking, unhealthy diet, stress and insufficient sleep
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You today
(your health state)
Who are you today?
Is it a result of your DNA? Your genes
(nature)
Your environment
(nurture)
Or is it a consequence of your environment?
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It’s Both
Genetic predisposition + Environmental Inputs
= Function / Dysfunction
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Understanding the genetic association with human biochemical function and connection with nutrition and lifestyle offers clinical tools with which to practice.
Nutritional Genomics In Practice
e.g. turmeric, food
45 gene variants
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What’s the implication for healthy living and ageing?
If your environment is problematic …
you eat badly, and live in a heavily polluted area, you do little exercise and suffer from stress, poor sleep
… then you are likely to exceed your genetic ability to adapt and you may eventually develop health issues.
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Connecting your DNA and lifestyle
Our DNA Reports makes connections between your DNA and lifestyle for healthy living and ageing.
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Putting it all together
Our focus is on those genetic variations that can be influenced by EPIGENTIC MODIFCIATIONS (lifestyle)
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Market acknowledgement
US Direct-to-Consumer DNA Testing Landscape (April 2018) Source: Mintel
myDNAhealth appears to be the only company that adds the epigenetic component to testing
and has a unique engagement model
That’s why we are different!
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Brain Health
Stress/ Sleep
Diet – Sugar &
Fat
Exercise
Obesity
Smoking
Gut Atopic
Disorders /IgE
Toxicity
Vitamin D
Inflamm-ation
APoE
MTHFR
Self-assessment online questionnaires (environment, lifestyle, habits, symptoms)
17
Practitioner Tools: A health risk analysis and preventive framework
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Obesity
Stress & Trauma /
Sleep
Diet
Vitamin D
Gut health
Atopic Disorders
Toxicity
Exercise/
Lifestyle
Inflammation
Nutri-genetics
Example: A metabolic risk analysis and preventative framework
Interactive secure client portal
Practitioner Tools: A health risk analysis and preventive framework
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Practitioner Tools: A health risk analysis and preventive framework
Inflammation
Stress Trauma Sleep
Diet
Infection&
Dysbiosis
Gut Permeab-
ility
Atopic Disorder
/IgE
Xenobiotic Toxicity
Endocrine Imbalance
EFA Balance
Genetic Mediators
Some Triggers to think about
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Summary
1. Multi faceted approach
2. Gain experience by practice
3. Try our risk analysis frameworks
4. Make sure your genetic testing company provides this type of support
5. If your client is healthy, then support through diet and lifestyle
6. If they are symptomatic, further functional testing may be needed
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More information: https://mydnahealth.co.uk/
Practitioner Support:
T: +44 (0)1603 861614
Come and talk to us today