What Government wants – can we deliver? Introducer Tony Raven Chief Executive, Cambridge Enterprise Chair Sir Keith O’Nions Chairman, Cambridge Enterprise Speakers Charlotte Heyes Deputy Director, Innovation & Place, BIS Professor Tim Dafforn Chief Scientific Advisor, BIS

2

Knowledge Exchange and Commercialisation of Research

supporting the successful exploitation of new ideas – products, services & processes

4

Innovation a key priority for UK

• Innovation can transform lives. • It can help to address our biggest societal and

economic challenges such as energy supply, food security and managing the impacts of demographic change.

• It enables businesses to develop new ideas, products and services, create new jobs and export opportunities.

Global innovation performance The UK has a long and strong history in science and innovation, and a world-leading reputation, being ranked second in the Global Innovation Index in 2015.

5

UK Innovation Performance: Innovation survey results 2015

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UK Innovation ambition

• We want to make Britain the best place in Europe to innovate, patent new ideas, start and grow a business

• We want an innovation system that promotes collaboration and the sharing of ideas to drive innovation opportunities

• Vital role for Universities and KE professionals in supporting this ambition - providing businesses with access to world class research, highly skilled people and world-leading experts

7

UK is doing well but still room to improve • Dowling Review

– Hiding the wiring – IP – Building an culture of

enterprise – Long term R&D

collaboration – SMEs – Underpinning Science &

Innovation funding

8

Responding to Dowling and beyond • Science & Innovation Funding • Innovate UK – single Innovation Fund • Creation of UK Research and Innovation • Maintaining Higher Education Innovation

Funding • HEFCE benchmarking KE performance

across the HE sector – best practice and the professionalization of knowledge exchange skills

9

National Innovation Plan • We are developing a National Innovation Plan

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What we want to see more of… • Focus on wider social impact – universities

as economic actors in their local areas and regions

• Collaboration and partnerships with business part of the culture, alongside excellent research AND across Universities

• Parity of esteem for those academics who invest themselves in commercialisation

• Further professionalisation of KE

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Scientific Commercialisation Why and How?

Professor Tim Dafforn Chief Scientific advisor

Quality of UK Science.

Academic Economics (Pre-2006)

Academic Economics (Post - 2006)

Universities

Experiences of Academic Commercialisaion

Hand Held device • Multiplexed

– more than one test at a time

• Multimodal – more than one type of

test (e.g. immuno & PCR)

Conventional approach: Highly developed detectors, ignore reagents

Compulsory 2 Day course in

entrepreneurship

1990

Development of low volume Linear

Dichroism system for biology

Dio

ptic

a S

cien

tific

Ltd

E

stab

lishe

d

+13

yrs

Entrepreneurial PhD supervisor

Demonstration that Linear Dichroism can be used to

detect mutations

+11

yrs

PATE

NT

FILE

D

Failed VC funding (£5 Million)

UG PhD PDRA

Spinner (£5K)

+15

Yrs

Matt Hicks Joins team as a PDRA

+17

yrs

Idea to use linear dichroism as a

platform detection technology

PATE

NT

FILE

D

Fellow

RDF £20K

EPSRC Follow-on fund

£100K

Use of M13 Bacteriophage in assay to increase

signal

+18

yrs

Medici Fellowship (1 Year + training)

BBSRC Enterprise Fellowship

(1 Year + training)

Line

ar D

iagn

ostic

s Lt

d Fo

rmed

+21

yrs

E. coli O157 Assay

LOD 107 cells/ml

Faculty

Equity split: UoB 35%

Investor 35% Founders (2) 35%

+22

yrs

E. coli O157 Assay

LOD 105 cells/ml M

att H

icks

Joi

ns

LD L

td a

s C

TO

Line

ar D

iagn

ostic

s Lt

d Fo

rmed

+23

yrs

Assay Multiplexing

DNA and Small molecule detection

“Handheld detector”

(Molecular Vision Ltd)

PATE

NT

FILE

D

PATE

NT

FILE

D

Knowledge transfer secondment to

Fleet Bioprocessing Ltd**

KTS to Molecular Vision Ltd

PhD with Dstl

First round investment

+24

yrs

IUK with MV Foods Ltd £500K

Em

ploy

ee 2

+25

yrs

Dstl Grant £500K (procurement linked,

unofficially!)

Develop Entrepreneurship

module Entrepreneurial

Mentoring

Academic – Industrial Partnership

R&D projects £4.22:£1 GVA R&D projects with Universities £9.67:1 GVA

Dowling Review 2015

32% UK economic growth comes from science and tech

+22

yrs

E. coli O157 Assay

LOD 105 cells/ml M

att H

icks

Joi

ns

LD L

td a

s C

TO

Line

ar D

iagn

ostic

s Lt

d Fo

rmed

+23

yrs

Assay Multiplexing DNA and Small

molecule detection

“Handheld detector”

(Molecular Vision Ltd)

PATE

NT

FILE

D

PATE

NT

FILE

D

Knowledge transfer secondment to

Fleet Bioprocessing Ltd**

KTS to Molecular Vision Ltd

PhD with Dstl

First round investment

+24

yrs

IUK with MV Foods Ltd £500K

Em

ploy

ee 2

+25

yrs

Dstl Grant £500K (procurement linked,

unofficially!)

Develop Entrepreneurship

module Entrepreneurial

Mentoring

Lessons learnt • Ideas “pipeline” is healthy • Sow the seed early (make it a natural part of the

science thought process) • Quality training a challenge** • Entrepreneurial activity is still risky in the UK

academic environment • Understand risk appetite

Ris

k Ap

petit

e

UG PhD PDRA Faculty Retired

Panel Questions & Answers