When Good Cells Go Bad!!

Regulators of Cell Growth and Cancer

Standard(s):

• BI5. a. Students know the general structures and functions of DNA, RNA, and protein.

• Explanation-5.a.-DNA-double helix-contain genetic info, RNA-single-stranded, copy of a section of DNA, protein-make up many parts of the body

Objectives:

SWBAT…

• Explain the origin of new cells.

• Describe the structure and function of DNA.

• Understand that cancer is caused by a malfunction of the cell cycle.

Cell Cycle Regulation

• Injuries (broken bones and cuts), need new cells

• Cells at edge of injury will rapidly divide producing new cells

• When the injury heals cell division slows down

Cell Cycle Regulation

• What tells cells to divide, make copies of their chromosomes, or enter another phase of the cell cycle?

• Many proteins regulate the cell cycle.

• Cyclin – causes a mitotic spindle to form in a non-dividing cell.

• Internal and External Regulators (proteins)

What is Cancer?

• Body’s cells lose the ability to control growth.

• Cancer cells do not respond to signals that control cell growth.

• Disease of cell cycle.

• Tumors (masses of cells)

Causes of Cancer

• Causes – smoking tobacco, radiation exposure, and viral infections

• Science can lead us to the cure for cancer

• Cancer affects all of us

Cancer Factshttp://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-029771.pdf

• 2011-571,950 expected cancer deaths

• Women-over 240,000 women expected to be diagnosed with breast cancer this year

• Men-over 240,000 men expected to be diagnosed with prostate cancer this year

• Cancers common in teenagers: Ewing’s sarcoma, leukemia, lymphoma, astrocytoma

Lung Cancer Cells

Skin Cancer

Breast Cancer Cells

Summary Questions

• How does your body replace a cell after an injury?

• Which type of molecules tell the cells to divide and grow?

• What is cancer?

• How can cancer be caused?

• Which types of cancer are commonly found in teenagers?