work on asthma
TRANSCRIPT
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Name: cyko shgu Topic : AsthmaSubmited to: chemist
Asthma
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Overview
Asthma – What is it?Classification of asthmaSymptoms of asthmaCausesWhat substances trigger asthma?Can asthma be cured? What YOU can do if you have asthma
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Asthma – What is It? Asthma is a chronic
lung disease that obstructs airflow
The obstruction is reversible
It involves difficulty in breathing due to – Inflammation (swelling)– Mucus in the airways– Tightening of muscles
around the airways
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Classification
Asthma is clinically classified according to the frequency of symptoms:
– Brittle asthma
– Asthma attack
– Status asthmaticus
– Exercise induced
– Occupational
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Brittle asthma
Brittle asthma is a term used to describe two types of asthma, distinguishable by recurrent, severe attacks.
Type 1 brittle asthma refers to disease with wide peak flow variability, despite intense medication.
Type 2 brittle asthma describes background well-controlled asthma, with sudden severe exacerbations.
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Asthma attack
An acute asthma exacerbation is commonly referred to as an asthma attack.
The classic symptoms are shortness of breath, wheezing, and chest tightness.
While these are the primary symptoms of asthma, some people present primarily with coughing, and in severe cases, air motion may be significantly impaired such that no wheezing is heard.
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Asthma attack
Signs which occur during an asthma attack include the use of accessory muscles of respiration.
there may be a paradoxical pulse (a pulse that is weaker during inhalation and stronger during exhalation), and over-inflation of the chest.
Blue color of the skin and nails may occur from lack of oxygen.
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Status asthmaticus
Status asthmaticus is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators and steroids.
Nonselective beta blockers (such as Timolol) have caused fatal status asthmaticus.
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Exercise induced
Here appears to be a relatively high incidence of asthma in sports such as cycling, mountain biking, and long-distance running, and a relatively lower incidence in weightlifting and diving.
It is unclear how much of these disparities are from the effects of training in the sport.
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Occupational
Asthma as a result of (or worsened by) workplace exposures is a commonly reported occupational respiratory disease.
Animal proteins, enzymes, flour, natural rubber latex, and certain reactive chemicals are commonly associated with work-related asthma.
When recognized, these hazards can be mitigated, dropping the risk of disease.
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Symptoms
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Symptoms of asthma
Common symptoms of asthma include:
Coughing
Wheezing, a whistling sound
Shortness of breath
Chest tightness
Sneezing & runny nose
Itchy and inflamed eyes
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Symptoms of asthma
Symptoms are often worse at night or in the early morning, or in response to exercise or cold air.
Some people with asthma only rarely experience symptoms, usually in response to triggers, whereas other may have marked persistent airflow obstruction.
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Causes
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Causes (Environmental factors)
Asthma is mainly caused by environmental factors.
Maternal tobacco smoking during pregnancy and after delivery is associated with a greater risk of asthma-like symptoms, wheezing, and respiratory infections during childhood.
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Causes (Environmental factors)
Low air quality, from traffic pollution or high ozone levels, has been repeatedly associated with increased asthma morbidity.
Recent studies show a relationship between exposure to air pollutants (e.g. from traffic) and childhood asthma.
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Causes (Environmental factors)
The occurrence of the disease and exacerbation of childhood asthma are affected by outdoor air pollutants.
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Causes (Genetic factors)
Over 100 genes have been associated with asthma.
But studies indicates that all these
genes are not associated with asthma under every condition
Some genetic variants may only cause asthma when they are combined with specific environmental exposures, and otherwise may not be risk factors for asthma
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What substances trigger asthma?
Type of Substance ExamplesAir pollutants, including dusts, smoke, mists & fumes
Diesel exhaust; tobacco smoke; mineral, rock, coal, & wood dusts; gases; fumes & vapors from aerosol agents, chemicals, cleaning materials, solvents, paints, welding & from heating & cooling metals quickly
Pollens, mites & molds Trees, flowers, weeds, hay, plants
Animal dander Birds, cats, dogs
Medications Aspirin, anti-inflammatory drugs
Foods Egg, wheat, nuts
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Can asthma be cured? Asthma can be controlled (but not cured)
by:– Avoiding triggers or reducing exposure to
triggers– Using medication to control symptoms
Medications - generally two types are used – Controller or long-term drugs
• Taken to prevent excess production of mucus & to reduce the inflammation and constriction of airway muscles
– Rescue or quick-relief drugs• Taken to relax muscles around the airways to improve
breathing
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Poorly controlled asthma leads to:
Increased visits to – Doctor, Urgent
Care Clinic or Hospital
Hospitalizations
Limitations in daily activities
Lower quality of life
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What YOU can do if you have asthma?
Identify and minimize contact with your asthma trigger(s)
Understand and take asthma medications as prescribed
Recognize early signs that your asthma is getting worse
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Enjoy life