world hepatitis day workshop...
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World Hepatitis Day Report 2018
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World Hepatitis Day
Workshop Report July 27-31, 2018
Islamabad, Lahore, Karachi
Safe Blood Transfusion Programme Ministry of National Health Services, Regulation & Coordination
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INDEX
1. List of participants……………………………………………………..……...…….…….3
2. Agenda…………………………………….………………………………...…...………..9
3. Speech by Prof. H.A Zaheer…………………………………...…………………......….12
4. Presentation on Hepatitis and Blood Safety, Pakistan Scenario….....………………..….16
5. Presentation on Blood Screening Technologies ……………….………….…..….…..…22
6. Presentation on Role of NAT screening in prevention and diagnosis………………………....25
7. Presentation on Hepatitis E, HBsAg Mutant & Occult HBV Infections in Pakistan.……........30
8. Presentation on Hepatitis Prevention in Punjab………………………………………….33
9. Presentation on …………………………………………………….…………………….33
10. Panel Discussion .…………………………………………….……………….....…...….34
11. Press Release ………..……………………………………………,……………..…........35
12. Press Coverage……..………………………………………………,……………………36
13. Photos…………………………………………………………………………...……..…38
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LIST OF PARTICIPANTS
Islamabad, July 27, 2018
Sr Name Designation Organization
1 Ms. Saira Tahir Programme Officer Safe Blood Tansfusion Programme
2 Ms. Kaenat Nasir Programme Officer Safe Blood Tansfusion Programme
3 Ms. Rabia Butt Representative Ali Medical Centre
4 Mr. Baber Hameed Representative Ali Medical Centre
5 Mr. Ibrar Rafique Representative Ali Medical Centre
6 Mr. Muhammad
Yousaf
Representative PIMS
8 Ms. Ujala Saeed Representative Excel Labs
9 Ms. Komal Victor Representative Excel Labs
10 Mr. Zain Shuja Representative NUST community service club
11 Ms. Eesha qureshi Representative NUST community service club
12 Mr. Abdul Hayee Representative NUST community service club
13 Ms. Mehak Nimra Representative National Institute of health
14 Mr. Zubair Niazi Executive Editor ADFLUX news/Jang lhr
15 Mr. Rajab Ali Lab Technician PAEC General Hospital
16 Ms. Sadia Rauf Representative Ali Medical Centre
17 Mr. Nadir ali Representative NUST community service club
18 Mr. Muhammd Asghar Representative PAEC General Hospital
19 Dr. Masooma Raza Consultant
Haematologist
PAEC General Hospital
20 Mr. Muhammad Aslam Trainer UHS Lahore
21 Ms. Saima Noman Supervisor Lab Quaid-e-Azam Int'l Hospital
22 Dr. Ayesha Tariq Molecular Biologist PAEC General Hospital
23 Dr Hafsa Aziz Senior Scientist NORI Hospital
24 Dr. M. Saeed Representative THQ Murree
26 Dr. M. safdar RMU Holy Family Hospital
27 Dr. Ali Mustafa Representative University of Lahore
28 Mr. Umair Hassan Representative Ali Medical Centre
29 Dr. Muhammad Idrees RMU Holy Family Hospital
30 Dr Tanveer-ul-Haq Zia Representative University of Lahore
31 Mr. M. Jawad Representative University of Lahore
32 Mr. Taimoor Haider
shah
Representative University of Lahore
33 Ms. Hannan Shaukat Representative University of Lahore
34 Ms. Ayesha Anis Representative University of Lahore
35 Ms. Minahil Ehsan Representative University of Lahore
36 Ms. Hira Tariq Representative University of Lahore
37 Ms. Abroo Basharat Representative University of Lahore
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38 Ms. Wania Sajid Representative University of Lahore
39 Ms. Fatima Mustafa Representative University of Lahore
40 Mr. M. Awais Qarni Representative University of Lahore
41 Ms. Anum Zahra naqvi Representative University of Lahore
42 Ms. Kainat Naseer Representative University of Lahore
43 Ms. Bisma Najjad Representative University of Lahore
44 Mr. Fahad Tufail Representative University of Lahore
45 Mr. Abdul Quddus Representative Kulsum Int'l Hospital
46 Mr. Naseer Masih Representative Maroof Int'l Hospital
47 Mr. Mukhtar Ahmed Representative Maroof Int'l Hospital
48 Ms. Amna Batool Representative Islamabad Medical and Dental College
49 Dr. Asfa Zawar Representative Islamabad Medical and Dental College
50 Ms. Mamoona javed Representative Islamabad Medical and Dental College
51 Mr. Ahmed Sultan Representative Islamabad Medical and Dental College
52 Mr. Bilal Abbas Representative Excel Labs
53 Mr. Abdul Waheed Representative Excel Labs
54 Mr. Fahad Hussain Representative University of Lahore
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Lahore, July 31,2018
Sr Name Designation Hospital
1 Dr. Shahid Ahmed Incharge Blood Bank Lahore General Hospital
2 Dr. M. Ali Khawaja Incharge Blood Bank Mayo Hospital Lahore
3 Dr. Fareed Ahmed Afzal Incharge Blood Bank Punjab Social Security
Hospital
4 Prof. Ayesha Ehsan Incharge Blood Bank Fatima Memorial Hospital
5 Dr. Ghulam Rasool Sial Incharge Blood Bank Ittefaq Hospital Trust
6 Dr. Aalia Khurram Khan Incharge Blood Bank Mid City Hospital Blood
Bank
7 Dr. Atta Ullah Roshani Incharge Blood Bank Sundus Foundation
8 Dr. M. Shafique Incharge Blood Bank DHQ Kot Khawaja Saeed
9 Dr. Farhan Shaukat Incharge Blood Bank Sharif Medical City Hospital
10 Dr. Asad Hayat Ahmed Incharge Blood Bank Shaukat Khanum Hospital
11 Dr. Zafar Iqbal Sheikh Incharge Blood Bank Surgimed Hospital
12 Dr. Zahid Asghar Incharge Blood Bank Doctor's Hospital & Medical
Centre
13 Prof. Dr. Abdur Rahman Incharge Blood Bank Gulab Devi Hospital
14 Dr. Yahya Saleem Incharge Blood Bank Cavalry Hospital Blood Bank
15 Col (Rtd) Dr. M. Jan Leghari Incharge Blood Bank Bahria Int'l Hospital
16 Dr. Asma Saadia Incharge Blood Bank Shalamar Hospital
17 Dr. M. Asif Naveed Incharge Blood Bank Al-Khidmat Blood Bank
18 Prof Dr. Mona Aziz Gilani Incharge Blood Bank Sheikh Zayed Hospital Lhr
19 Dr. Shakeel Arif Incharge Blood Bank Akram Medical Complex,
Excel Lab
20 Dr. Tanveer-ul-Islam Incharge Blood Bank Amina Bashir Memorial Trust
21 Dr. M. Farooq Khan Incharge Blood Bank Farooq Hospital
22 Dr. Naveed Toosy Incharge Blood Bank OMC Hospital
23 Brig (Rtd) Dr. Abdus Sattar Incharge Blood Bank Bahria Int'l Hospital
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24 D.r M. Nadir Khan Incharge Blood Bank Iqbal Medical Complex
25 Dr. Malika Incharge Blood Bank Farooq Hospital
26 Dr. Farzana Aslam Incharge Blood Bank Lady Aitchison Hospital
27 Dr. Shahida Mohsin Incharge Blood Bank Muhammad Shahbaz Sharif
Hospital
28 Dr. Muhammad Zafar Incharge Blood Bank Hamid Latif Hospital Lhr
29 Dr. Imtiaz Waqar Incharge Blood Bank Lady Willington Hospital
30 Dr. Hashmat Mumtaz Rao Incharge Blood Bank Arif Memorial Teaching
Hospital
31 Dr. Alia Waheed Incharge Blood Bank Akhtar Saeed Trust Hospital
32 Dr. Farhana Incharge Blood Bank Fatimid Foundation
33 Dr. M. Asif Hussain Khan Incharge Blood Bank Aadil Hospital
34 Dr. Saima Irum Incharge Blood Bank Jinnah Hospital Lahore
35 Dr. Ahsan Masood Khan Incharge Blood Bank Masood Hospital
36 Dr. Muhammad Qadeer Incharge Blood Bank District Blood Unit Services
Hospital
37 Dr. Shabnam Bashir Incharge Blood Bank Punjab Thalassameia
Prevention Programme
38 Dr. Nazish Saqlain Incharge Blood Bank Children Hospital Lhr
39 Prof. Nisar Ahmed Incharge Blood Bank Children Hospital Lhr
40 Dr. Ayesha Imran Incharge Blood Bank National Medical Centre
DHA
41 Dr. Zafar Iqbal Incharge Blood Bank IBTS
42 Dr. Ather Incharge Blood Bank PBTA
43 Dr. Asif Naveed Incharge Blood Bank King Edward Medical
University
44 Mr. Ahmed Representative Almueed BDS
45 Mr. Hassan Ameer Representative Sheikh zahid hospital
46 Mr. Ali Ahmed Representative PUCIT
47 Mr. M. Rashid Representative SOCH foundation
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48 Mr. Khuram Representative USA
49 Mr. Arslan Representative Shadra green blood
50 Mr. Awais Representative AIMC
51 Mr. Hassan Representative PBDS
52 Mr. Naimat ullah Representative Hajvery
53 Mr. Mubashir Representative UMT
54 Mr. Noman Representative Ali Baba Foundation
55 Mr. Hamza Representative We Care foundation
56 Mr. Jawaid Awan Representative Life foundation
57 Mr. Rana osama Representative Save humanity
58 Mr. Syed Abdullah Representative GCU
59 Mr. Ashir Representative PAC
60 Mr. Hammad Representative Ripha
61 Mr. Talha Naseer Representative Jido jahad
62 Mr. Azka Representative LMDS
63 Mr. Shoaib Representative UET
64 Mr. Umer Khan Representative LSE
65 Mr. Nauman Representative COMSATS Lhr
66 Mr. Hassan Raza Representative University Of Education
67 Mr. Aquib Representative Bahria University
68 Mr. Shahrukh Taimoor Representative Beaconhouse National
University
69 Mr. Asim Representative University Of Lahore
70 Mr. Zain Naveed Representative FAST University
71 Mr. Mujahid Representative LEEDS University
72 Mr. Usman Representative UCP
73 Ms. Hijab Fatima Representative GC University
74 Mr. Saad Chawla Representative LUMS
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Karachi, July 30, 2018
Sr. Name Designation Organization
1. Prof Syed M. Irfan Consultant
Haematologist
Liaqat National Hospital,
2. Dr. Shabneez Hussain
Consultant
Haematologist
Fatimid Foundation
3. Dr. Zahid Hasan Ansari Secretary Sindh Blood Transfusion Authority
4. Prof. Ikram uddin Ujjan Consultant
Haematologist
Liaqat University of Medical &
Health Sciences,
5. Dr Bushra Moeez, Head of Blood Bank
Services
Aga Khan University Hospital
6. Dr. Saba Jamal Head of Blood Bank
Services
The Indus Hospital
7. Dr. Sarfaraz Hussain Jafri Director of Blood Bank
Services
Hussaini Blood Bank
8. Dr. Muhammad Anwar Assistant Professor Jinnah Postgraduate Medical Centre
(JPMC)
9. Dr. Waleed Bin Azhar COO Fatimid Foundation
10. Mr. Akif Ali Atif Representative National Institute of Blood Disease
(NIBD)
11. Dr. Agha Umer Daraz Consultant
Haematologist
Liaqat National Hospital,
12. Mr. M. Moin Ahmed Manager Blood Bank Jinnah Postgraduate Medical Centre
(JPMC)
13. Dr. Saadia Saeed Pathologist SIUT
14. Dr. Ashraf Memon Consultant Pathologist -
15. Dr. Saeeda Incharge Blood Bank PWA, Civil Hospital
16. Dr. Munira Borhany Consultant
Haematologist
National Institute of Blood Disease
(NIBD)
17. Mr. Mehdi Rizvi Representative Mohammadi Blood Bank
18. Mr. S. Arif Ali Founder & Chairman Help International Welfare Trust
19. Dr. Kashif H. Ansari President Omair Sana Foundation
20. Mr. Wasiq Paracha President Patients’ Welfare Association
Civil Hospital,
21. Mr. Muhammad Iqbal Chairman Kashif Iqbal Thalassemia Care
Centre (Trust)
22. Mr. Javeed Qaim Ali Project Incharge Burhani BB and Thalassaemia
Centre
23. Dr. Asima Zahid
HOD MBA Health
Management
Programme,
Institute of Business Management
24. Prof. Agha Akbar Head of Pathology
Department
Dow University of Health Sciences
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AGENDA
World Hepatitis Day Marriott Hotel, Islamabad, July 27, 2018
Agenda
10:30 am Registration
11:00 am Recitation from the Holy Quran
11:05 am Welcome Remarks
11:10 am Hepatitis and Blood Safety: Pakistan Scenario Prof. Hasan Abbas Zaheer
11:30 am Hepatitis Screening Technologies Brig. (R) Prof. Javaid Usman
11:50 am Role of NAT screening in prevention and diagnosis Dr. Ayesha Junaid
12:10 pm Hepatitis E, HBsAg Mutant & Occult HBV Infections in Pakistan Mr. Usman Waheed
12:30 pm Panel Discussion
o Sub-standard manual screening kits
o Screening Technology options for Hepatitis detection
o Rising Prevalence of Hepatitis in Blood Donors
o Hepatitis B and C Prevalence in Thalassaemia and Haemophilia
01:00 pm Address by Chief Guest
01:15 pm Group Photograph
01:20 pm Lunch
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World Hepatitis Day PC Hotel, Lahore, July 31, 2018
Agenda
10:30 am Registration
11:00 am Recitation from the Holy Quran
11:05 am Welcome Remarks
11:10 am Hepatitis and Blood Safety: Pakistan Scenario Prof. Hasan Abbas Zaheer
11:30 am Hepatitis Screening Technologies Dr. Shabnam Bashir
11:50 am Hepatitis Prevention in Punjab Dr. Syeda Zahida Sarwar
12:10 pm Hepatitis E, HBsAg Mutant & Occult HBV Infections in Pakistan Mr. Usman Waheed
12:30 pm Panel Discussion
o Sub-standard manual screening kits
o Screening Technology options for Hepatitis detection
o Rising Prevalence of Hepatitis in Blood Donors
o Hepatitis B and C Prevalence in Thalassaemia and Haemophilia
01:00 pm Address by Chief Guest
01:15 pm Group Photograph
01:20 pm Lunch
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World Hepatitis Day Marriott Hotel, Karachi, July 30, 2018
Agenda
10:30 am Registration
11:00 am Recitation from the Holy Quran
11:05 am Welcome Remarks
11:10 am Hepatitis and Blood Safety: Pakistan Scenario Prof. Hasan Abbas Zaheer
11:30 am Hepatitis Screening Technologies Dr. Ashraf Memon
11:50 am Early detection of viral hepatitis in healthy donors by NAT screening
Prof. Bushra Moiz
12:10 pm Hepatitis E, HBsAg Mutant & Occult HBV Infections in Pakistan Mr. Usman Waheed
12:30 pm Panel Discussion
o Sub-standard manual screening kits
o Screening Technology options for Hepatitis detection
o Rising Prevalence of Hepatitis in Blood Donors
o Hepatitis B and C Prevalence in Thalassaemia and Haemophilia
01:00 pm Address by Chief Guest
01:15 pm Group Photograph
01:20 pm Lunch
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SPEECH BY PROF. HASAN ABBAS ZAHEER, NATIONAL COORDINATOR SBTP
Globally, viral hepatitis is a major public health challenge that requires urgent attention and response.
The disease caused 1.34 million deaths in 2015, a number comparable to annual deaths caused by
tuberculosis worldwide and higher than that caused by HIV. But while the tuberculosis and HIV
epidemics are being managed successfully and their mortalities reducing, the viral hepatitis epidemic
is still on the rise. To address this alarming scenario, the UN General Assembly in 2015 adopted the
2030 Agenda for Sustainable Development which called on the international community to eliminate
hepatitis and followed it up by presenting the ‘Global Health Sector Strategy on Viral Hepatitis’ in
the World Health Assembly in 2016. To implement this Strategy, a global plan was outlined in the
‘Global Health Report 2017’ to contain and reverse the hepatitis epidemic through a number of key
interventions and scaled up interventions. To highlight the scale of the hepatitis epidemic and raise
awareness about its prevention the World Health Organization has designated July 28 as the World
Hepatitis Day.
Viral hepatitis is the inflammation of the liver caused by five main hepatitis viruses commonly referred
to as types A, B, C, D and E. While all hepatitis viruses can cause acute hepatitis, Hepatitis B, C and
D frequently cause chronic hepatitis, which can lead to progressive scarring of the liver (cirrhosis)
and to primary liver cancer (hepatocellular carcinoma). HBV and HCV cause 96% of the mortality
from viral hepatitis and usually occur as a result of parenteral contact with infected body fluids.
Common modes of transmission include transfusion of contaminated blood or blood products,
invasive medical procedures using contaminated equipment and for hepatitis B transmission from
mother to baby at birth, from family member to child, and also by sexual contact. Hepatitis A and E
infections are usually self-limiting and are typically caused by ingestion of contaminated food or
water. Acute infection may occur with limited or no symptoms, or may include symptoms such as
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jaundice (yellowing of the skin and eyes), dark urine, extreme fatigue, nausea, vomiting and
abdominal pain. Hepatitis can also be caused by other infections, toxic substances (e.g. alcohol, certain
drugs), and autoimmune diseases.
Credible epidemiological evidence clearly demonstrates that elimination of viral hepatitis is possible.
Universal coverage of Hepatitis B vaccine has established excellent results in containing the spread
of Hepatitis B epidemic. The introduction of recent antiviral drugs treatment for chronic Hepatitis C
infections has recorded cure rates exceeding 95%. Strengthening the blood supply system in countries
with advanced health care systems has made blood transfusions very safe and largely risk free as far
as transmission of transmissible infections are concerned. Improving injection safety in many
countries has contained the spread of hepatitis through this mode of transmission. The design of the
response to global hepatitis epidemic is based on all these proven successful interventions. Even at
this early stage, several countries with committed political leadership have demonstrated encouraging
results in containing hepatitis epidemic through reduction in prices of essential medicines, reduction
in cost of screen testing, improving blood transfusion screening systems and ensuring universal
coverage of Hepatitis B vaccination.
In Pakistan, all the five main types of viral hepatitis (A, B, C, D, and E) are epidemic. Most of the
population is affected by Hepatitis A (Childhood) or E (Adulthood) with maximum morbidity. At the
same time, Pakistan is also facing the epidemic of Hepatitis B and C. The last national survey
conducted in 2008 showed 2.5% prevalence of HBV and 4.9% prevalence of HCV. HBV was more
prevalent in males (2.9%) as compared to females (2.0%). But there was no gender difference in the
HCV prevalence and overall Pakistan has the highest HCV prevalence after Egypt. The common
causes of transmission identified in the Report and other research publications include contaminated
blood transfusions, therapeutic injections, reuse of syringes and medical devices, injecting drug use,
dental procedures, renal dialysis, shaving by barbers and commercial sex work.
In countries with developed health care systems, high standards of quality of blood and blood
components throughout the entire blood transfusion chain has led to high level of human health
protection and generated faith and confidence in the system among the donors as well as the users.
Challenging standards of quality and safety for the collection, testing, processing, screening, storage
and distribution of human blood and blood components have been set and successfully attained. As a
result, incidence of transmission of hepatitis viruses through contaminated blood transfusions is
extremely rare in such countries.
On the other hand, the health care systems of developing countries continuously face challenges of
inadequate supply of safe blood and an increase in the prevalence of transfusion associated infections
including hepatitis. Until 2010, the situation in Pakistan was also no different and the quality of blood
transfusion services was adversely affected due to the imbalance in the supply and demand. According
to national estimates, 3.5 million donations are made annually in Pakistan and this huge amount of
blood collected used to be a potential key vector for transmitting infectious diseases, affecting about
7.4 percent of the population. Screening for transfusion-transmissible infections is a critical part of
the process of ensuring that transfusion is as safe and infection free as possible. In a fragmented blood
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transfusion system and with an only incipient culture of voluntary donations, a strong reliance on
family replacement donors, and the lack of systematic screening strategy, the infection risks were at
the upper end. A large community of thalassaemic patients in the country (6% carrier rate) faced an
imminent risk of acquiring infection through blood transfusion since they receive multiple
transfusions every year.
To reduce the risk of transmission of infections through blood transfusions and improve the blood
transfusion services, the Government of Pakistan with the support from the Government of Germany
initiated the blood safety systems reforms in Pakistan in 2010. The reforms included the formulation
of a national blood policy and strategic framework and the establishment of a national blood
transfusion programme. At the federal level, the government’s Safe Blood Transfusion Programme
(SBTP) performs the role of a central coordinating body to oversee policy planning, provide strategic
guidelines, set standards, monitor and evaluate programmes, liaise with development partners and
report on international commitments. The Programme is developing a nationwide blood transfusion
infrastructure which consists of constructing and equipping a network of regional blood centres and
renovation and refurbishment of the existing hospital blood banks. The model is consistent with
international recommendations of separation of blood production and blood utilization and regulated
through a functioning oversight mechanism. The Programme also covers the associated technical work
to prepare the system to function according to the international guidelines and directives.
The overall objective of the Programme is to provide safe, efficacious and quality assured blood to
the people of Pakistan which is free from infections, particularly hepatitis, as much as possible. The
infrastructure developed so far has started to provide service delivery and the people are thus deriving
direct benefit of the blood sector reforms in the shape of better and safer blood transfusion services.
In the current second phase of the project the size and scope of the project is being expanded
exponentially to cover the hitherto uncovered regions.
The establishment of systems to ensure that all donated blood is screened for transfusion-transmitted
infections including hepatitis is a core component of the SBTP. Through this Programme training
activities and research studies have been conducted with the aim to improve the standard of screening
in the blood centers and preventing the spread of infections through transfusions. National screening
strategies and algorithms have been developed after extensive consultations. The adoption of these
technical initiatives has contributed significantly to improvements in blood safety in the country. The
regulatory oversight has been strengthened through the operationalization of the largely dormant
provincial and regional blood transfusion authorities. These authorities now register and license all
blood centers in their respective regions and ensure that all blood establishments adhere to the basic
minimum criteria for licensing including the equipment, HR and resources required for quality assured
screening of the mandatory hepatitis and other markers. One impact of the empowered blood
regulatory authorities has been the significant decline in the widespread use of the cheap substandard
manual screening kits used in the public and private sector blood banks. The gradual consolidation of
services through the nationwide establishment of the Regional Blood Centers and the adoption of this
model in the existing facilities has not only provided economy of scales but also improved the
screening standards. The SBTP is actively promoting automation and use of modern technology in
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the blood centers which has also contributed in strengthening the screening standards. The regulatory
authorities are also working on promoting the culture of quality in the blood services and developing
a national external quality assurance system.
Despite all these milestone achievements by the flagship national blood programme gaps still remain.
But with the gradual expansion in the coverage of services through the new system managed by the
SBTP with continued support by the German partners strengthening of the credible partners and the
regulatory authorities and phasing out of the smaller but numerous unsafe service providers the risk
of hepatitis transmission through blood transfusions is likely to be successfully contained in Pakistan
in the near future.
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PRESENTATION ON HEPATITIS AND BLOOD SAFETY IN PAKISTAN
Prof. Hasan Abbas Zaheer (Isb, Lhr, Khi)
National Coordinator, Safe Blood Transfusion Programme
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PRESENTATION ON HEPATITIS SCREENING TECHNOLOGIES
By Brig. Javaid Usman, Consultant Safe Blood Transfusion Programme (Isb),
Dr. Shabnam Bashir, Associate Prof. Fatima Jinnah Hospital (Lhr),
Dr. Ashraf Memon, Consultant National AIDS Contol Programme (Khi)
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PRESENTATION ON ROLE OF NAT IN BLOOD TRANSFUSION SERVICES
Prof. Ayesha Junaid (Isb)
Incharge Blood Bank, Shifa Inrernational Hospital
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PRESENTATION ON EVALUATION OF SCREENING EFFECTIVENESS OF HBsAG
AND ANTI-HCV RAPID TEST KITS IN PAKISTAN
Mr. Usman Waheed (Isb, Lhr, Khi)
Technical Expert, Safe Blood Transfusion Programme
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PRESENTATION ON HEPATITIS PREVENTION IN PUNJAB
Dr. Zahida Sarwar (Khi)
Program Manager, Hepatitis Control Program
PRESENTATION ON ROLE OF SCREENING IN PREVENTION AND DIAGNOSIS OF
HEPATITIS
Dr. Mateen Izhar (Lhr)
Consultant Micobiologist, Sheikh Zayed Hospital Lahore
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PANEL DISCUSSION
Discussion Points
➢ Sub-standard manual screening kits
➢ Screening Technology options for Hepatitis detection
➢ Rising Prevalence of Hepatitis in Blood Donors
➢ Hepatitis B and C Prevalence in Thalassaemia and Haemophilia
Discussion & Recommendations
• There are various types of screening assays available for screening of blood. However, not
all assays are suitable in all situations and each assay has its limitations which need to be
understood and taken into consideration when selecting assays.
• TPHA is best of all the screening assays available in the country for screening of syphilis
• Thalassaemics are among the most transfused patients and therefore are most exposed to
transfusion transmitted infections, all these patients usually receive multiple blood
tmnsfusions which in most cases are not screened or screened by cheaper and unreliable
techniques.
• Poor quality rapid devices are being used in most parts of the country.
• Prevalence of HBV, HCV and HIV in our population and especially among patients with
multiple transfusions like beta thalassaemics should be known to avoid the spread of further
blood borne infection of these viruses.
• Government of Pakistan has taken different initiatives like vaccination, patient safety,
blood screening, education and awareness about disease but still there is high prevalence
of hepatitis in Pakistan.
• Punjab government has recently taken initiative to shift screening in public sector hospitals
from rapid devices to ELISA.
• There are specific hepatitis pockets in central Punjab. These are the areas which need to be
targeted specifically and awareness campaigns are to be run for these people.
• The treatment of hepatitis is very costly and a developing country like Pakistan cannot
afford such high costs. Therefore more focus should be on preventive measures.
• All thalassaemia centres should adhere to minimum screening standards for all
thalassaemia patients
• The life expectancy of transfusion dependent thalassaemia major patients can be improved
by transfusing screened blood and blood products. It will be much cheaper to prevent these
diseases rather than treat them.
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PRESS RELEASE
Blood Program celebrates World Hepatitis Day
The World Hepatitis Day is celebrated all over the world on July 28 to highlight the global spread of
the hepatitis epidemic. The Day is also celebrated in Pakistan widely by the stakeholders since
Pakistan is among the high burden countries for hepatitis. The Safe Blood Transfusion Programme
(SBTP) organized a Seminar in Islamabad to celebrate this Day. The Seminar participants included
a large number of representatives of the blood banks, blood donor organizations, NGOs, university
and college students and other partners.
Prof. Hasan Abbas Zaheer, National Coordinator, SBTP in his presentation briefed about the global,
regional and national aspects of the hepatitis epidemic. He described in detail the global strategy and
response to halt and prevent the spread of hepatitis. The international effort led by the World Health
Organization is supported by all the member states. Pakistan is also a signatory to these international
commitments made in the UN General Assembly in 2015 which adopted the 2030 Agenda for
Sustainable Development which called on the international community to eliminate hepatitis. These
commitments were articulated in the ‘Global Health Sector Strategy on Viral Hepatitis’ presented in
the World Health Assembly in 2016.
One of the important modes of transmission of hepatitis in Pakistan is the unsafe contaminated blood
transfusions. Prof. Zaheer enumerated the efforts of the SBTP to make transfusions in Pakistan
infection free and strengthen the blood transfusion services. These efforts included the development
of a new nationwide blood transfusion infrastructure (construction of regional Blood Centers) with
the support of the German government through KFW Development Bank grant where blood
transfusion services are being provided according to the international recommended guidelines
adopting good laboratory practices for the screening of infections including Hepatitis. Other SBTP
initiatives include developing technical manuals, guidelines, SoPs and training of the human resource
which strengthen the blood screening systems. SBTP has also revived the blood regulatory authorities
in all the provinces and regions which are now strictly enforcing quality screening systems in the
blood centers. The regulatory authorities have also managed to curb and significantly reduce the
rampant use of substandard manual screening devices, a major source of spread of hepatitis in
Pakistan. As a result of these concerted efforts by SBTP blood safety standards particularly the
standard of blood screening has improved considerably.
The Seminar also included some technical presentations by eminent experts including Prof. Javaid
Usman, Prof. Ayesha Junaid and Mr. Usman Waheed on the topics of screening assays for hepatitis,
Nucleic Acid testing and blood screening guidelines and algorithms. The Seminar also included an
extensive Panel discussion session on Blood Safety and Hepatitis Spread. The discussion topics
included Availability of cheap substandard kits; screening technology options for hepatitis detection;
Rising prevalence of hepatitis among blood donors; and High Hepatitis B and C prevalence in
Thalassaemia patients. The panel discussion provided an excellent opportunity for an interactive
session where the participants engaged in a knowledgeable debate with eminent experts about
hepatitis prevention.
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PRESS COVERAGE
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PHOTOS
Islamabad
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Lahore
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Karachi
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Safe Blood Transfusion Programme
Hostel A, NISTE building, Off Sufi Tabbasum Road,
Sector H-8/1, Islamabad, Pakistan.
Phone: +92 51 925 0307-8 | +92 51 9250 313
Fax: +92 51 8250 309
Email: [email protected]
Website: www.sbtp.gov.pk