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Clinical Pathology

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Page 1: 04 clinical pathology

Clinical Pathology

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Clinical Pathology

Located in Room 2020 Full service laboratory

Hematology, clinical chemistry, urinalysis, cytology, coagulation, blood bank

Provide 24 / 7 service Daytime M-F: 8:00 am – 9:00 pm Weekends Sat and Sun: 8:00 am – 11:00 pm After hours: On call night technicians

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Administrative

Darla Montalvo

Emily Kearney

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Technical Daytime

Myriah Vineyard

Barbara Dott

Elaine Nicholds

Al Brant

Catherine Samway

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TechnicalAfter Hours

Wendy Browning

Chase RatliffJeri Grotberg

Amber DucoteCourtney Duncan

Melanie Aschenberg

Marty Moore

Heidi Ertresvaag

Not pictured

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Pathology Residents

Dr. Angela Wilcox

Dr. Seth Chapman

Dr. Mary Nabity

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Pathologists

Dr. Mark Johnson Dr. Shashi Ramaiah

Dr. Karen Russell

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What We Do

Clinical Service Research Support Residency Training Teaching

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What We Do

Laboratory support for Clinics and Research Hematology (8,200 samples) Clinical Chemistry (10,000 samples) Cytology (1,600 samples) Urinalysis (2,500 samples) Coagulation (2,100 samples) Blood Bank (350 samples)

Central receiving for outside labs Send-out laboratory (6,200 samples)

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What We Do

Residency Training“The goal of the resident training program in

veterinary pathology is to provide veterinarians with the necessary background and knowledge to pursue successful careers in veterinary pathology.”

Generally have 2 - 4 residents 3 year program for clinical training

Teaching Clinical service Graduate courses

An additional 3 - 4 years to complete a PhD

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What We Do

Residency Training, con’t Since ~1995

7 (past) residents + 3 (current) residents 6 / 7 are ACVP Diplomates 2 / 7 have received a PhD

Where are they now? Academia (TAMU, Purdue, Auburn, MD Anderson) Industry (Eli Lilly) Referral Labs (IDEXX)

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What We Do

Teaching 4th year veterinary students (2-week

rotation) 3rd year veterinary student elective 2nd year veterinary students

General Pathology VTPB 922 Systemic Pathology VTPB 923

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What We Do

“Laboratory Visitors” Rotations in the laboratory (~ 1 - 4 wks)

Interns, residents, faculty 28 Texas A&M 22 Other US universities 4 International universities 2

Technicians 1

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For More Info andHow to Contact Us

Main Lab Number (979) 845 - 9180

http://www.cvm.tamu.edu/clinpath/

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Clinical Immunology

Infectious Agents

Immune-Mediated Phenomena

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Clinical Immunology

Monthly Tests 2005 2006

Heartworm 63 53

EIA (Coggins) 46 37

FeLV/FIV 14 13

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Clinical Immunology Other Tests: Infectious Agents

Virus:

EIAV (ELISA)

FeLV (ELISA)

Feline Heartworms

Antibody (ELISA)

Antibody + Antigen(ELISA)

Fungal

Blastomyces dermatitdis (AGID)

Coccidioides immitis (AGID)

Cryptococcus neoformans Antigen

Histoplasma capsulatum (AGID)

Fungal AGID (4 Fungi)

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Clinical Immunology Other Tests: Immune-Mediated Process

Coombs

Antinuclear AntibodyLE Prep

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Clinical Immunology Future?

Flow Cytometry

Immunophenotyping (Leukemia)

Reticulated Platelet CountReticulocyte Count

Immune-Mediated Phenomena:Platelet-Associated ImmunoglobulinErythrocyte-Associated Immunoglobulin

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Clinical Immunology Immunophenotyping?

Canine Undifferentiated Myeloid Leukemia

Mature Neutrophils

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Clinical Immunology Reticulated Platelets / Reticulocytes ?

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Clinical Immunology Reticulated Platelets / Reticulocytes ?

responded to therapyno bone marrow analysis available

Immune-Mediated Thrombocytopenia

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Clinical Immunology Reticulated Platelets / Reticulocytes ?

azathioprine therapy2° pneumonia euthanasia

bone marrow: hypoplasia

Myasthenia Gravis

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Clinical Immunology Surface Immunoglobulin?

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Clinical Immunology Future?

Molecular Diagnostics

Clonality by PCR (Lymphoma/Reactive)

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Clinical Immunology

Infectious Agents

Immune-Mediated Phenomena

More?

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Clinical Microbiology

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Clinical Microbiology

• Where we are:– Located in 2015 VMTH– Laboratory hours 8-5, Monday-Friday; 9-noon

on Saturday– Student worker on call at 412-3336 (old pager

not functioning) – Dr. Libal cell 218-0520– home 764-3940

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Clinical Microbiology

• Who we are– Rosa Gonzalez- Laboratory supervisor– Elizabeth Fernandez- Technician– Kay Duncan- Technician ½ time– Todd Stewart- student worker– Lane Roasa- on call/student worker– Melissa C. Libal

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Kay Duncan

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Rosie Gonzalez

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Todd Stewart

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Lizzie Fernandez

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Clinical Microbiology

• What we do– Clinical service– Teaching– Research support– Residency training

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Clinical Service

• 2005– Bacterial cultures- 3726– Susceptibility testing- 2647– Fungal cultures- 170– Environmental cultures of large and small

animal clinics- 6243– Clostridium toxin testing- 91

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Teaching

• Senior veterinary student rotations

• Undergraduate

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Other

• Research support– Antimicrobial resistance– Johnes– Epidemiology of infectious disease

• Residency program– Goal

• Graduate degree

• ACVM boards

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Newly acquired equipment

• Bactron I anaerobe hood– Increase quantity/quality of anaerobic culture

capability

• Trek (Sensititre) MIC system– testing on food animal pathogens– testing on small animal/equine pathogens for

veterinary drugs– Research capability

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Clinical Parasitology

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Clinical Parasitology what we are

• A lab designated to the diagnosis of parasitic disease in vertebrate hosts

• Aid in evaluation of animal wellness programs

• Aid in research programs

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Clinical Parasitologywho we are

Craig, Cyr, Holeman, Snowden

Whagela, Wagner

ElGayar, Smith

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Clinical ParasitologyWhat We Do

• Located in Room 320 VMA• Laboratory diagnosis of parasitic

– Helminths– Protozoa – Arthropods

• Provide service– Daytime M-F: 8:30 am – 5:00 pm– After hours:by arrangement

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What We Do

• Laboratory support – Clinics and Research projects

• Fecal examinations • Blood examinations • Serology, PCR (limited)• Tissues, worm counts, identification

• Consultation• 1 – 5 telephone calls / day veterinarians, general

public, extension, industry

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Clinical ParasitologyWho We Work For

• Clinical Service: teaching hospital TVMDL veterinarians

• Research Support: CVM TAES other

• Teaching students producers

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What We Do

• Teaching– 4th year veterinary students (2-week rotation)– 2nd year veterinary students Parasitology

VTPB 920– Graduate students Helminthology

VPAR 601 or Protozoology VPAR 604

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Immunopathology/ Immunopathology/ Histopathology ServiceHistopathology Service

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PersonnelPersonnel

Dr. Andy AmbrusDr. Andy AmbrusSupervisor:Supervisor:

ImmunopathologyImmunopathology

lablab

Rosemary VollmarRosemary VollmarSupervisor:Supervisor:

Histopathology labHistopathology lab

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PersonnelPersonnel

Susan HernandezSusan HernandezHistotechnician/Histotechnician/

ImmunotechnicianImmunotechnician Chaitali Chaitali

MukherjeeMukherjeeHistotechnicianHistotechnician

Allison TewellAllison TewellStudent workerStudent worker

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PersonnelPersonnel

Shannon DavisShannon Davis Dawn CurrinDawn Currin Cheryl ChambleeCheryl Chamblee Sharon DickersonSharon Dickerson

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MissionMission

To supply histopathology and To supply histopathology and immunopathology support to the immunopathology support to the VTH, pathology services, and VTH, pathology services, and research components at TAMU research components at TAMU

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GoalsGoals

To provide rapid as possible turn To provide rapid as possible turn around times for diagnostic and around times for diagnostic and research histopathology specimensresearch histopathology specimens

To provide quality specimens for all To provide quality specimens for all servicesservices

To provide accurate immunostaining To provide accurate immunostaining for challenging diagnostic cases and for challenging diagnostic cases and research interests research interests

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Laboratory Accessions 05Laboratory Accessions 05

Total ProceduresTotal Procedures 22,57322,573

Total Proc/Emb/H&ETotal Proc/Emb/H&E 13,46113,461

Total Special StainsTotal Special Stains 2,5752,575

Total Immunopathology Total Immunopathology ProceduresProcedures 1,5721,572

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HistologyHistology

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ImmunohistochemistryImmunohistochemistry

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ImmunocytochemistryImmunocytochemistry

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ImmunocytochemistryImmunocytochemistry

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Anatomic Anatomic pathologypathology

NecropsyNecropsy Surgical pathologySurgical pathology

DermatopathologyDermatopathology

OrthopedicOrthopedicpathologypathology

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Surgical pathologySurgical pathology

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PeoplePeople

Dr. Roy Pool. Dr. Roy Pool. Dr. Joanne Mansell. Dr. Joanne Mansell. Dr. Jairo Nunes.Dr. Jairo Nunes. Dawn CurrinDawn Currin Shannon Davis. Shannon Davis.

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MissionMission

Service. Surgical pathology Service. Surgical pathology support for the VMTH small and support for the VMTH small and large animal clinicslarge animal clinics

Teaching. 6 anatomic pathology Teaching. 6 anatomic pathology residents rotate with faculty.residents rotate with faculty.

Research. Mostly collaborative Research. Mostly collaborative with clinicians in small and large with clinicians in small and large animal clinics.animal clinics.

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ServiceService

Real time web site for surgical Real time web site for surgical resultsresults

http://vtpb-www.cvm.tamu.edu/surgpath/dailyhttp://vtpb-www.cvm.tamu.edu/surgpath/daily.lasso.lasso

Approximately 800-900 cases/yrApproximately 800-900 cases/yr

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We encourage clinician-We encourage clinician-pathologist interaction. pathologist interaction.

Review slides with clinicians, Review slides with clinicians, clinical residents, and studentsclinical residents, and students

Love to be invited to clinic to see Love to be invited to clinic to see clinical casesclinical cases

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TeachingTeaching

There are 6 anatomic pathology There are 6 anatomic pathology residents who rotate on the residents who rotate on the service with faculty.service with faculty.

Residents and students in the Residents and students in the clinic are welcome to come and clinic are welcome to come and look at slides of their cases.look at slides of their cases.

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ResearchResearch

Collaborative publications with Collaborative publications with clinicians in the VMTH, and clinicians in the VMTH, and pathologists at other institutions. pathologists at other institutions.

Presentations at national and Presentations at national and international meetings.international meetings.

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Dermatopathology Dermatopathology

National and state specialty serviceNational and state specialty service Approx 2000 cases/yrApprox 2000 cases/yr One of 3 universities with dermpath One of 3 universities with dermpath

services.services. Provides cases for teaching, Provides cases for teaching,

publications, and presentations at publications, and presentations at national & international meetings.national & international meetings.

Joanne Mansell. Melanie Buote Joanne Mansell. Melanie Buote training on service. Previous faculty; training on service. Previous faculty; Dunstan, Credille, MecklenburgDunstan, Credille, Mecklenburg

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Orthopedic Orthopedic pathologypathology National and state specialty National and state specialty

serviceservice Approx 260 cases/yrApprox 260 cases/yr One of 2 universities with One of 2 universities with

osteopath serviceosteopath service Provides cases for teaching, Provides cases for teaching,

publications, and presentationspublications, and presentations Dr. PoolDr. Pool