1 using qualitative methods in health disparities research anna nápoles, ph.d. center for aging in...
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Using Qualitative Methods In Health Disparities Research
Anna Nápoles, Ph.D.Center for Aging in Diverse Communities
Division of General Internal MedicineMay 21, 2009
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Objectives
MIXED METHODS APPLICATIONS
Refine frameworks, concepts Develop measures Develop intervention
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What is the Role of Qualitative Research?
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Understanding Disparities: Moving Research into the Community
Qualitative research: Identify how research methods may need
to be tailored Identify mechanisms of disparities Welcomes community engagement
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a
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OUTCOME
What’s in the Black Box?
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Deconstructing Markers
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When are Qualitative Methods Used?
Open-ended interviews typically used in new areas of study
Useful for in-depth knowledge about issues, especially in less studied groups
Especially critical in cross-cultural studies due to lack of information
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What are Qualitative Methods?
Data consist of words, not numbers Richly descriptive, open-ended Focus on inductive analytic approaches Many types: ethnography, participant-
observation, direct observation, focus groups, in-depth interviews
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Combining Qualitative and Quantitative Methods
Prior to quantitative: to develop concepts, framework, hypotheses, and content for structured survey items or interventions
After quantitative: – to help identify reasons for survey items not
performing well quantitatively– to explore possible explanations for
unexpected results
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Sampling in Qualitative Research
Purposive, nonprobabilistic Deliberately select settings, persons or
events to best answer research questions
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Goals of Purposeful Sampling
Achieve representative, typical settings, individuals, or activities
Set up contrasts to examine differences between settings or individuals
(Maxwell JA. Sage Publications, Inc., 1996)
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1. Refining a Conceptual Framework
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Meaning of Events
Richness of Qualitative Data
Contextual Influences on
Behavior
Processes Underlying Observed
Relationships
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In-depth Individual Interviews
Semi-structured, open-ended Capture complexity Interactions of individuals with their
environments
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In-depth Interviews (cont.)
Advantages– useful for areas with little prior work
– allow for detailed exploration of relationships, phenomenon, esp. sensitive topics
– Can easily revise questions to clarify issues raised in earlier interviews
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In-depth Interviews (cont.)
Disadvantages– fewer participants
– less able to address generalizability
– less theory driven, less confirmatory
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In-Depth Interviews to Expand Framework
Similar employment rates among low-income families with and without special needs children (1996 US Census Bureau)
Conclude child care systems adequately meeting needs of special needs
Qual interviews - enormous strain on family relations, scarce programs, working nights, high turnover
(Sunhua L. 2002)
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Asking the Right Questions
NOT:
Are you currently: working FT, working PT, disabled, looking for work, etc.
BUT:
How has your current work situation affected your family?
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Revised Framework
Child with special needs Child with special needs
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Employment status of parents
Financial strainStress
Family functioningResources
Job instability
Original Framework
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2. Developing Measures of Concepts
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Focus Groups
Open-ended guided group discussion with probing of responses
Led by experienced moderator; usually 1 - 2 hours
Purposeful sampling of 6-10 homogenous participants per group
Participants stimulate comments of others Audio-record and transcribe discussion
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Focus Groups-Logistics
Moderator skills: listening, communication, negotiation, cultural similarity to participants
Costs of group: $600 - $1000 per group (incentives, audio-taping, transcription, translation, food)
Convenient and hospitable community setting In-person recruitment works best with
telephone/mail reminders
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Focus Groups
Advantages– group stimulates fruitful discussion
– spontaneity leads to discovery of new issues and factors
Disadvantages: scheduling, skilled moderator, group setting may be inappropriate
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Example: Measures of Cultural Sensitivity of Clinicians
Conducted 19 focus groups with 163 participants
61 African Americans, 45 Latinos and 55 non-Latino Whites
What do or don’t your doctors understand about your culture or health beliefs?
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Identify Themes (Codes): How Culture Might Affect Health Care and Outcomes
CAM Discrimination Doctor Culture Ethnicity of MD Family Immigration
Language Modesty Nutrition Patient
submissiveness Spirituality
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Define Domains of Each Cultural Sensitivity Domain: CAM
Definition: MD’s knowledge and acceptance of non-Western, non-biomedical, holistic approaches to health or healing
“When I told her I was on estrogen, it was refreshing to hear suggestions about alternative types of herbal treatments.”
AA woman > 50
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Develop Items Based on Definition and Wording Used by Participants
Over the past 12 months, how often did doctors…
..ask if you would be interested in hearing more about alternative types of herbal treatments? (CAM domain)
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Reducing Item Pool
Criteria:– maintain breadth of concept, multiple
items/concept– reduce redundancy (but OK to test alternate
versions of items)– eliminate items that are unclear, complex, lack
face validity, or will not translate well
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Cognitive Interviews toPretest Measures
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Cognitive Interviews
Derived from social and cognitive psychology to explore processes respondents use to answer survey questions
Diagnostic tool for pretesting survey questions
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Purpose of Cognitive Interviews
To learn … if respondents understand words and
phrases as intended (meaning) about the process of answering the
questions whether items are unacceptable about the usefulness of response choices
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Writing Probe Questions
From reduced set of items, select potentially problematic items for pretesting
Write open-ended scripted probe questions– worded to reveal if suspected problem
with a specific item is present
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Types of Cognitive Probes
General– Tell me what you were thinking when you
answered that question– How easy or difficult was it to answer that
question? Why? Explore meaning of word or phrase
– I asked you how often doctors take a genuine interest in you. What does the phrase “genuine interest” mean to you?
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Types of Cognitive Probes (cont.)
Retrieval– How did you remember that?
Judgment– Why did you pick that number for your answer?
Response– Do you think that most people answer this
question honestly?Collins D. Quality of Life Research 2003. 12:229-38.
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Types of Cognitive Probes (cont.)
Redundancy– How is the phrase “give you advice about your diet
and exercise” different from the phrase “talk to you about your diet and exercise”?
Acceptability– When I asked you how often you felt discriminated
against by doctors because of your race or ethnicity, you answered (read answer given). Were you offended by this question?
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Types of Cognitive Probes (cont.)
Cultural appropriateness– I asked you how often doctors asked you about
your health beliefs? What does the term ‘health beliefs’ mean to you?
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Sampling for Cognitive Interviews
Usually do not use representative samples Include respondents from major segments
of population to be sampled for main survey
Approximately 5-15 interviews/group, but may involve several rounds
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Recruiting for Cognitive Interviews
Explain how their help fits into larger study, process of creating questions
Explain their role clearly: – “help us learn how to ask better questions”– “help us make questions clearer for others” – “help us to identify problems with questions”
Pay subjects $25 - $50, interview is demanding If survey is long, pretest different sections on
different subjects
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Conducting Cognitive Interviews
Individual face-to-face, in-depth interviews
Standard administration of closed-ended items
Administer probe questions at the end (or concurrently)
Typically 1 hr interview Each interview audiotaped and transcribed
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Data Analysis of Cognitive Interviews
Create summary of most significant problems:– Annotated questionnaire: use electronic
version of survey to enter comments for each item directly under each question
– Aggregate item-by-item comments over multiple interviews
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Content Analysis of Items and Probes
Using qualitative analysis software, review all dialogue during standard administration of closed-ended items and open-ended probes– can reveal source of problems– can help in deciding whether to keep, modify or
drop items Allows you to examine dialogue by item
– within groups– across groups/languages
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Example of Results: Unclear Phrase
Original item: Have you had any medical tests or procedures in past year?– 26% of respondents asked for clarification
Probe: What did you include as medical tests or procedures?
Medical test or procedures unclear (e.g., asked if it included dental or cosmetic procedures)
Item revised to include examples:– Have you had any medical tests or procedures, such as blood
tests, x-rays, or cancer screening tests?
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Example of Results: Interpreting the Question
Original item: How satisfied are you with the amount of stress or worries in your life?
Probe: Did you answer this question in terms of stress, worries, or both?
AA and Spanish-speakers - tended to answer in terms of worries
Revised item– How satisfied are you with the amount of worries in your
life?Warnecke RB, et al. JNCI Monographs No. 20, 1996; 29-38.
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Pretesting in Diverse Populations
Greatest problems are with question interpretation - simplify
Sometimes English concepts not meaningful in other languages or meaning varies across groups
Response sets can also be problematic
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Advantages of Cognitive Interviews Identifies where responses might be
affected by cultural or group experiences Suggests ways to revise items, responses Improves validity of questions
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Disadvantages of Cognitive Interviews
Flags problems, but significance of the problem is a subjective judgment– When do you need to revise or drop items?
Based on small number of respondents Time and labor intensive
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3. Developing Interventions to Reduce Disparities
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How did I get here?
48Source: http://www.ahrq.gov/clinic/3rduspstf/behavior/fig2shell.htm
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Themes for Designing Peer Support Intervention
Project Aims
Identify barriers to and benefits of psychosocial health services
Preferred mode for intervention
Preferred intervention content
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Mixed Methods to Develop Interventions
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Themes
Informational needs Early intervention Fear of impending death Peer support Powerlessness Role of family
Spirituality Advocacy Difficulty expressing
feelings, needs Cultural congruence Trust building
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Implications for Peer Intervention
Low-literacy cancer info in Spanish Early case identification Emotional support Dispel myths Peer-delivered Engage family in providing support
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Implications for Peer Intervention (cont.)
Advocate for patient CBT Client activation Cultural congruence of peer and client Develop trust over time, multiple personal
contacts
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Content Analysis of Qualitative Interviews
Use qualitative analysis software to review and code transcripts
Allows you to examine codes and their frequencies:– within groups or individuals– across groups or individuals– sorted by research interest/questions,
e.g. ethnic differences, specialists vs. generalists
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Coding of Transcripts
Directly interpret individual remarks/instances Aggregate instances into categories and
analytically define category or class Search for patterns-consistencies and
inconsistencies Can manually code in margins of transcripts
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Manuscript Preparation
Describe unit of analysis Describe and define codes-these can be
categories/classes, processes, behaviors Provide illustrative quotes Can provide frequencies of number of
units coded for each category
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Manuscript Preparation
Report consistencies and inconsistencies
Organize themes or codes into higher, interrelated level of analysis and abstraction - framework
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Manuscript Preparation
Describe strategies for validating conclusions:
multiple coders, deductive and inductive approaches, triangulate findings across methods or sources, verified by participants, attention to negative cases
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Limitations of Qualitative Methods
Small number of respondents limits generalizability
Time and labor intensive analyses
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Advantages
Very rich and detailed Unstructured aspects allows for on-the-
spot probing Can creatively explore potential
hypotheses
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Conclusions: Usefulness of Qualitative Methods
VITAL to health disparities research
INSIGHTS into relevant frameworks, questions, themes, constructs, items
EXPANDS our conceptual models of mechanisms of disparities-identify unanticipated factors
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“How-To” Resources
Ward H, Atkins J. From their lives: a manual on how to conduct focus groups of low-income parents. Institute for Child and Family Policy, Edmund S. Muskie School of Public Health, University of Southern Maine, 2002: http://muskie.usm.maine.edu/focusgroupmanual/manual.htm
Kruegar RA, Casey MA. Focus Groups: A Practical Guide for Applied Research, 3rd ed. Thousand Oaks, CA: Sage Publications, Inc., 2002.
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Grant Applications
Qualitative Methods in Health Research: Opportunities and Considerations in Application and Review
OBSSR, NIH
http://obssr.od.nih.gov/pdf/Qualitative.pdf
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Nature of Qualitative Data
Exploratory, descriptive
Identify unanticipated phenomena and influences
Generate hypotheses about processes underlying observed relationships