1.skin histol lina 2011

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    Structure of Skin and Its

    Appendages

    dr. Ni Made Linawati, M.Si

    Histology departmentMedical Faculty of Udayana University

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    OUTLINE

    1. Skin

    ! "#ick skin

    ! "#in skin

    layer, cells

    $. Skin %ppendages

    ! Se&aceous gland! Sweat gland

    ! Hair

    ! Nail

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    Structures of the Skin

    'pidermis

    (ermis

    Hypodermis

    Hair follicle

    Sweat pore

    Nerves

    MuscleSweat

    gland

    Fat

    Se&aceous

    gland

    Hair)loodvessels

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    Functionals of the skin structure

    1. *ermea&ility &arrier epidermis

    $. *rotection from pat#ogen,uv

    +. "#ermoregulation sweat gland, &lood vessel

    . -eception of continual sensations from t#e

    environment merkel cells, meisners

    . '/cretion sweat gland

    0. *#ysical appearance melanocyte

    . 2ound repair3regeneration

    4. %&sorpsion epidermis

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    kin layer

    1. Epidermis

    2. Dermis

    3.Hypodermis

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    EPIDERMIS 5rigin from ectoderm Stratified s6uamous keratini7ed epit#elium or stratums cells types

    Dermis 5rigin from mesoderm 8onnective tissue cells, matri/9 fi&ers $ layerscontents

    HIPOE!"IS! Loose connective tissue! %ccumulate of adipocyte cells

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    CELLS OF THE EPIDERMIS

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    I##igrant $ells of The Epider#is

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    %eratinoc&tes

    "#e largest population ofcells

    %rranged in five layer

    Morp#ology different

    depend on t#e strata

    8ells in diff. strata produced

    diff. type of keratin protein

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    %eratinoc&te differentiation

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    "elanoc&tes

    Neural crest

    epidermis Synt#esi7e melanin (eep layer of epidermis Morp#ology rounded or

    cu&oid9 proc of cytoplasmstratum spinosum 8ytoplasmgranules

    melanosomescytocrinesecretion

    *rotect us from uvradiation ::::::

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    E!"IS

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    !eticular La&er

    Papillar& La&er

    dermis: Papiar! and Reticuar a!ers

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    SU($UTANEOUS LA)E!

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    S%IN APPENA'ES

    S')%S'5US =L%N(

    S2'%" =L%N(

    H%>-

    N%>L

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    SE(ASEOUS 'LAN

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    SE(ASEOUS 'LAN

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    S*EAT 'LAN

    '88->N' S2'%" =L%N(; M'-58->N'

    %*58->N' S2'%" =L%N(UN('- "H'

    >NFLU'N8' 5F H5-M5N'S

    M5(>F>'( =L%N( 8'-UM>N5US %N(

    M%MM%-? =L%N(

    S'8-'"5-? UN>", (U8",

    M?5'*>"H'L>%L 8'LLS

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    S"eat #ands

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    S*EAT 'LANS +E$$!INE,

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    S*EAT 'LANS +APO$!INE,

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    S-eat 'lands

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    HAI!

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    HAI! Filamentous, keratini7ed

    structures t#at pro@ect

    from t#e epidermalsurface of t#e skin

    "ype+

    Hair follicles develop from

    epidermis and invade t#edermis and #ypodermis

    Hair root and dermalpapilla#air &ul&

    Hair s#aft

    8ells matri/ cells,melanocytes

    HAI! FOLLI$LE

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    HAI! FOLLI$LE

    Functions warm, s#ield,filter

    Hair growt# cyclesanagen, catagen, telogen

    NAIL

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    NAIL

    Aeratini7ed epit#ellialcells arranged in plates of#ard keratin

    "erm nail plate, nail &ed,nail matri/, nail root,eponyc#ium,#yponyc#ium, lunula

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    SU""A!)

    "#ick vs t#in skin different

    ! in epidermis Bstratum vs C

    Skin appendages

    ! Sweat =land Becrine vs apocrine S=C

    ! Se&aseous =land

    Secretion9 location9 open9 #ormonal influence9

    etc

    ! Hair, nail

    skin vs #air vs nail differ in keratin type

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    THAN% )OU