2014 medical imaging

LocationTown & Country Resort and Convention CenterSan Diego, California, USA

Conferences and Courses15–20 February 2014

www.spie.org/micall

Call for PapersSubmit your abstract by 12 August 2013

www.spie.org/micall

2014

MI2014 Call Cover#2.indd 1 5/9/13 9:59 AM

TECHNOLOGIES• Physics of medical imaging• Image processing• Computer-aided diagnosis• Image-guided procedures,

robotic interventions, and modeling

• Biomedical applications in molecular, structural, and functional imaging

• Image perception, observer performance, and technology assessment

• PACS and imaging informatics: next generation and innovations

• Ultrasonic imaging, tomography, and therapy

• Digital pathology

Present your work at the premier event for medical scientists and practitioners in the fi eld of imaging

Call for PapersConferences and Courses: 15–20 February 2014Town & Country Resort and Convention CenterSan Diego, California, USA


+1 360 676 3290 • [email protected] • twitter (#SPIEMI) 1

Plan to Participate The SPIE Medical Imaging meeting is the internationally recognized premier forum for reporting state-of-the-art research and development in medical imaging. We invite contributions that address topics ranging from underlying fundamental scientifi c principles, to technology developments, scientifi c evaluation, and clinical application. The symposium covers the full range of medical imaging modalities including medical image acquisition, display, processing, analysis, perception, decision support, and informatics. Broad topics of interest include the following:

• imaging physics, systems analysis and modeling• x-ray imaging and computed tomography• ultrasonic acquisition and processing• magnetic resonance imaging (MRI)• molecular imaging• digital pathology• emerging image acquisition technologies• tomographic image reconstruction• quantitative imaging• image processing and analysis• computer-aided detection and diagnosis• computational models• image-guided therapies• visual rendering of complex datasets• visual perception and observer performance• physiological and functional interpretation of image data• clinical evaluations of new technologies• image data management (storage, retrieval, transmission)• medical informatics.

We encourage your contributions to Medical Imaging, where your work will be heard and read by colleagues from around the world. For those authors wishing to publish their work after the conference in a journal, SPIE copyright policy grants authors the right to include material from their Medical Imaging Proceedings papers in a peer-reviewed journal of their choice.

2014 Symposium Chairs:

Ehsan Samei, Duke Univ. (USA)

David Manning,Lancaster Univ.(United Kingdom)

SPIE is the international society for optics and photonics, a not-for-profi t organization founded in 1955 to advance light-based technologies. The Society serves nearly 225,000 constituents from approximately 150 countries, offering conferences, continuing education, books, journals, and a digital library in support of interdisciplinary information exchange, professional growth, and patent precedent. SPIE provided $3.2 million in support of education and outreach programs in 2012.

SPIE INTERNATIONAL HEADQUARTERS

P.O. Box 10, Bellingham, WA 98227-0010 USA Tel: +1 888 504 8171 or +1 360 676 3290 Fax: +1 360 647 1445 [email protected] • www.SPIE.org

MI14 call insides#5.indd 1 5/9/13 9:49 AM

2 SPIE Medical Imaging 2014 Call for Papers • www.spie.org/micall

MI101 Physics of Medical Imaging (Bruce R. Whiting/Christoph Hoeschen) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3

MI102 Image Processing (Sebastien Ourselin/Martin A. Styner) . . . . . . 4

MI103 Computer-Aided Diagnosis (Stephen Aylward/Lubomir M. Hadjiiski) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

MI104 Image-Guided Procedures, Robotic Interventions, and Modeling (Ziv R. Yaniv/David R. Holmes III). . . . . . . . . . . . . . . . . 6

MI105 Image Perception, Observer Performance, and Technology Assessment (Claudia R. Mello-Thoms/Matthew A. Kupinski) . . . 7

MI106 Biomedical Applications in Molecular, Structural, and Functional Imaging (Robert C. Molthen/John B. Weaver) . . . . . 8

MI107 PACS and Imaging Informatics: Next Generation and Innovations (Maria Y. Law/Tessa S. Cook) . . . . . . . . . . . . . . . . . 10

MI108 Ultrasonic Imaging and Tomography (Johan G. Bosch/Marvin M. Doyley) . . . . . . . . . . . . . . . . . . . . . . . 9

MI109 Digital Pathology (Metin N. Gurcan/Anant Madabhushi) . . . . . 12

General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13

Sponsorship Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13

Poster Session Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14

Abstract Submission . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

Contents

Cooperating Organizations AAPM—American Association of Physicists in Medicine

APS—American Physiological Society

CARS—Computer Assisted Radiology and Surgery

MIPS—Medical Image Perception Society

RSNA—Radiological Society of North America

SIIM—Society for Imaging Informatics in Medicine

WMIS—World Molecular Imaging Society

The DICOM Standards Committee

Photos Courtesy of Ken Hanson

Abstract Due Date: 12 August 2013



Physics of Medical Imaging (MI101)Conference Chairs: Bruce R. Whiting, Univ. of Pittsburgh (USA); Christoph Hoeschen, Helmholtz Zentrum München GmbH (Germany)Conference Co-Chair: Despina Kontos, The Univ. of Pennsylvania Health System (USA)Program Committee: Andreu Badal, U.S. Food and Drug Administration (USA); Kirsten Boedeker, Toshiba Medical Research Institute USA (USA); Hilde Bosmans, Univ. Hospitals of KU Leuven (Belgium); Guang-Hong Chen, Univ. of Wisconsin School of Medicine and Public Health (USA); Mats E. Danielsson, Royal Institute of Technology (Sweden); Mini Das, Univ. of Houston (USA); Maria Drangova, Robarts Research Institute (Canada), Univ. of Western Ontario {Canada); Thomas G. Flohr, Siemens Healthcare (Germany), Eberhard Karls Univ. Tübingen {Germany); Stephen J. Glick, Univ. of Massachusetts Medical School (USA); Michael Grass, Philips Research (Germany); Marc Kachelrieß, German Cancer Research Ctr. (DKFZ) (Germany); Karim S. Karim, Univ. of Waterloo (Canada); Hee-Joung Kim, Yonsei Univ. (Korea, Republic of); Joseph Y. Lo, Duke Univ. (USA); Robert M. Nishikawa, The Univ. of Chicago (USA); Norbert J. Pelc, Stanford Univ. (USA); Jinyi Qi, Univ. of California, Davis (USA); John A. Rowlands, Thunder Bay Regional Research Institute (Canada); John M. Sabol, GE Healthcare (USA); Taly G. Schmidt, Marquette Univ. (USA); Anders Tingberg, Lund Univ. (Sweden); John Yorkston, Carestream Health Technology and Innovation Ctr. (USA)

Abstract Due Date: 12 August 2013All submissions must include: a 100-word abstract for early release, a 250-word abstract, and a one to four page supplemental fi le (see Submission Guidelines)

This conference will cover all aspects of image formation in medical imaging, including systems using ionizing radiation (x-rays, gamma rays) or non-ionizing techniques (ultrasound, optical, ther-mal, magnetic resonance, or magnetic particle imaging). Papers of a theoretical nature or papers reporting new experimental results are invited. Topics of particular interest include experimental methods and results regarding image performance, image reconstruction, detector materials and elec-tronic design, analytical and computer modeling of imaging systems, and novel methods for image formation including the physics of contrast media. The conference will cover predicted and measured system performance, including image noise and contrast, spatial and temporal resolution, and in-herent artifacts. Systems of interest include those producing projection, tomographic, volumetric, dynamic, or time resolved studies, along with systems using specialized approaches for depth or tissue discrimination. Work directed toward the imaging of human subjects, small animals, or tissue specimens are welcome. Original papers are especially requested in the following areas:Imaging Science • Physics of signal detection and image formation • Object characterization and contrast mechanisms • Characterization of detector and system

performance (MTF, NPS, DQE, task- and observer-based)

Technology• Novel medical imaging systems and methods

including contrast media / nanoparticles. • Properties of scintillating, photoconductive, or

other sensor materials • Novel sources of radiation • Image reconstruction methods (e.g., for CT,

tomosynthesis, SPECT and PET, optical imaging, MRI, etc.)

• Multi-energy (spectral) x-ray and CT imaging • Computer simulation of imaging systems

including models for radiation sources, imaged objects, physical interactions, and detectors

• Phantoms (physical and numerical) • Radiation (e.g., optical) and signal transport • Radiation dose, dosimetry, and dose effects

(risk), as well as possible stratifi cation Devices and Applications• Advanced multi-slice or cone beam CT systems • Advanced radiographic, fl uoroscopic, or

angiographic systems (including phase contrast and diffraction)

• Advanced applications (clinical, translational, preclinical, basic science, biomarkers)

• Non-ionizing radiation systems (ultrasound, MRI, optical, thermal, magnetic particle imaging)

• Small animal imaging systems • Nuclear medical imaging methods • Multi-modality imaging devices • Low-cost imaging devices with global health

applications • Imaging applications in therapy (e.g., radiation

therapy, surgery, interventions)

TOPIC AREAS: For this conference onlyDuring the submission process, you will be asked to choose no more than three topics from the following list to assist in the review process. Please select in order of importance.• ALG - Algorithmic developments, simulations,

calibration, classifi cation, etc. (for CT and tomosynthesis reconstruction use dedicated categories)

• APPS - Applications, e.g. cardiovascular, oncology, image guided interventions (for breast imaging use dedicated category)

• CON – Physics of contrast enhancement using contrast media / nanoparticles

• CT - All conventional CT topics (for reconstruction, cone beam, and multi-energy use dedicated category)

• CTCB - Cone beam CT • CTME - Multi-energy CT • CTREC - CT image reconstruction • DET - Detector technology; scintillators,

photoconductors, diodes, TFT • DOSE - radiation dose, dosimetry, and dose effects • MAM - Imaging of the breast (any device) • METR - Measurement methods (MTF, NPS, DQE,

eDQE, gDQE, Spectra, ...) • IMG - Imaging methods including optical, MR,

ultrasound, etc. (for x-ray or nuclear based methods use dedicated categories)

• NUC – nuclear medical imaging innovations (for reconstruction use dedicated category)

• PER - Observer or perception-based performance evaluations of systems

• PHT - Work involving development of phantoms or anatomical simulation models

• PHS - Phase contrast imaging • RADT - Radiation Transport Calculations • RECON - Image reconstruction including SPECT,

PET, OCT and tomosynthesis • SYS - Reports on complete systems, prototypes,

products including small animal or microscopic imaging devices

• TSY - Tomosynthesis (for reconstruction use dedicated category)

• XIM - X-ray imaging, x-ray sources, techniques, scatter (for detectors, mammography, and reconstruction use dedicated categories)

• XME - Multi-energy radiography or mammography (for CT use CTME instead)

• OTHER - Other technical areas



SPIE Medical Imaging 2014

Image Processing (MI102)Conference Chairs: Sebastien Ourselin, Univ. College London (United Kingdom); Martin A. Styner, The Univ. of North Carolina at Chapel Hill (USA)Program Committee: Paul Aljabar, King’s College London (United Kingdom); Mostafa Analoui, The Livingston Group, LLC (USA); Elsa D. Angelini, Telecom ParisTech (France), Columbia Univ. (USA); Kyongtae Ty Bae, Univ. of Pittsburgh Medical Ctr. (USA); Christian Barillot, IRISA / INRIA Rennes (France); Benoit M. Dawant, Vanderbilt Univ. (USA); Baowei Fei, Emory Univ. (USA); Aaron Fenster, Robarts Research Institute (Canada); Alejandro F. Frangi, The Univ. of Sheffi eld (United Kingdom); Mona K. Garvin, The Univ. of Iowa (USA); Guido Gerig, The Univ. of Utah (USA); David R. Haynor, Univ. of Washington (USA); Tobias Heimann, Siemens AG (Germany); Bennett A. Landman, Vanderbilt Univ. (USA); Tianhu Lei, Univ. of Pittsburgh Medical Ctr. (USA); Boudewijn Lelieveldt, Leids Univ. Medisch Ctr. (Netherlands); Murray H. Loew, The George Washington Univ. (USA); Cristian Lorenz, Philips Medizin Systeme GmbH (Germany); Frederik Maes, Katholieke Univ. Leuven (Belgium); Vincent A. Magnotta, The Univ. of Iowa Hospitals and Clinics (USA); Sunanda D. Mitra, Texas Tech Univ. (USA); Kensaku Mori, Nagoya Univ. (Japan); Nassir Navab, Technische Univ. München (Germany); Mads Nielsen, Univ. of Copenhagen (Denmark); Wiro Niessen, Erasmus Univ. Medical Ctr. (Netherlands), Delft Univ. of Technology {Netherlands); Brian S. Nutter, Texas Tech Univ. (USA); Josien P. W. Pluim, Univ. Medical Ctr. Utrecht (Netherlands); Jerry Prince, Johns Hopkins Univ. (USA); Sonia Pujol, Harvard Medical School (USA), Brigham and Women’s Hospital (USA); Punam K. Saha, The Univ. of Iowa (USA); Olivier Salvado, CSIRO (Australia); Julia A. Schnabel, Univ. of Oxford (United Kingdom); Philippe Thévenaz, École polytechnique fédérale de Lausanne (Switzerland); Jayaram K. Udupa, The Univ. of Pennsylvania Health System (USA); Tomaž Vrtovec, Univ. of Ljubljana (Slovenia); Andreas Wahle, The Univ. of Iowa (USA)


Original papers are invited on all aspects of the processing and analysis of medical, small animal, or cellular images, with applications in medicine, biological, and pharmaceutical research. Of inter-est are algorithms applied to all imaging modalities, including x-ray, DSA, CT, MRI, nuclear medicine, optical, ultrasound, macroscopic, and microscopic imaging. Papers dealing with the challenges of bringing advances in research laboratories into clinical application are particularly welcomed. Papers typically involve research that includes one or more of the following categories (in alpha-betical order):

Categories • Classifi cation • Compressive sensing/sparse reconstruction

methods • Computational anatomy and atlases • Deformable geometry • Diffusion MRI analysis • Functional imaging (e.g. fMRI) and connectivity

analysis • Image representation and compression • Image restoration and enhancement • Mathematical morphology • Machine Learning • Model-based image analysis • Motion/time series analysis • Multiresolution and wavelets • Open software for medical image processing

and translational research • Pattern detection and recognition • Population/clinical studies • Quantitative image analysis • Registration methodologies • Segmentation methodologies • Shape representation and analysis • Statistical methodology • Stereoscopic x-ray processing and visualization • Texture representation and analysis • Validation, including creation of ‘ground truth’

image repositories • Voxel/deformation/tensor-based morphometry

TOPIC AREAS: For this conference only During the submission process, you will be asked to choose no more than three topics from the list above to assist in the review process.Critical Dates

Abstract Due Date: 12 August 2013

Post-Meeting Manuscript Due Date: 20 January 2014Please Note: Submissions imply the intent of at least one author to register, attend the conference, present the paper as scheduled, and submit a full-length manuscript for publication in the conference proceedings.



Call for Papers

Computer-Aided Diagnosis (MI103)Conference Chairs: Stephen Aylward, Kitware, Inc. (USA); Lubomir M. Hadjiiski, Univ. of Michigan Health System (USA)Program Committee: Samuel G. Armato III, The Univ. of Chicago (USA); Susan M. Astley, The Univ. of Manchester (United Kingdom); Kyongtae Ty Bae, Univ. of Pittsburgh Medical Ctr. (USA); Matthew S. Brown, Univ. of California, Los Angeles (USA); Heang-Ping Chan, Univ. of Michigan Health System (USA); Marleen de Bruijne, Erasmus MC (Netherlands), Univ. of Copenhagen {Denmark); Thomas M. Deserno, RWTH Aachen (Germany); Catalin Fetita, Telecom SudParis (France); Hiroshi Fujita, Gifu Univ. School of Medicine (Japan); Maryellen L. Giger, The Univ. of Chicago (USA); Hayit Greenspan, Tel Aviv Univ. (Israel); Horst K. Hahn, Fraunhofer MEVIS (Germany), Jacobs Univ. Bremen {Germany); Nico Karssemeijer, Radboud Univ. Nijmegen Medical Ctr. (Netherlands); Jong Hyo Kim, Seoul National Univ. College of Medicine (Korea, Republic of); Joseph Y. Lo, Duke Univ. (USA); Marius George Linguraru, Children’s National Medical Ctr. (USA), George Washington Univ. (USA); Michael F. McNitt-Gray, Univ. of California, Los Angeles (USA); Kensaku Mori, Nagoya Univ. (Japan); Janne J. Näppi, Massachusetts General Hospital (USA), Harvard Medical School (USA); Meindert Niemeijer, IDx, LLC. (USA); Noboru Niki, Univ. of Tokushima (Japan); Carol L. Novak, Siemens Corp., Corporate Technology (USA); Nicholas A. Petrick, U.S. Food and Drug Administration (USA); Ronald M. Summers, National Institutes of Health (USA); Kenji Suzuki, The Univ. of Chicago (USA); Georgia D. Tourassi, Oak Ridge National Lab. (USA); Bram van Ginneken, Radboud Univ. Nijmegen Medical Ctr. (Netherlands); Eva M. van Rikxoort, Radboud Univ. Nijmegen Medical Ctr. (Netherlands); Rafael Wiemker, Philips Research (Germany); Axel Wismüller, Univ. of Rochester (USA); Xiaofeng Yang, Emory Univ. (USA)


TOPIC AREAS: For this conference onlyDuring the submission process, you will be asked to choose no more than three topics (one Applica-tions, and up to two others) from the following list to assist in the review process. Choose one or more applications topic from the following list:• Applications: Breast • Applications: (Cardio-)Vascular • Applications: Colon and other Gastrointestinal

Tract • Applications: Eye (including retina) • Applications: Head and Neck • Applications: Liver • Applications: Lung • Applications: Microscopy and Histopathology • Applications: Multiple Organ Systems • Applications: Musculoskeletal • Applications: Oncology • Applications: Prostate • Applications: Novel Applications • Applications: Other Organ Systems

Choose up to two topics from the following list:• Detection • Characterization and staging • Classifi cation and/or machine learning • CAD system quality and/or risk assessment • Segmentation • False positive reduction • Feature extraction • Data management and/or reference libraries • Content-based image retrieval • Visualization and interaction • Validation and/or quantitative analysis • Observer studies • Human factors in CAD • Decision support systems • Comparative evaluation of different CAD systems • Combining or fusing different CAD systems • Other (please specify)

This conference will provide a forum for research-ers involved in development and application of computer-aided diagnosis and detection systems. Original papers are requested on all aspects of CAD, including segmentation, pattern recognition, feature extraction, classifi er design, workstation design, human interaction, database construction, and evaluation. CAD methods involving any medical imaging modality are welcome, including x-ray, CT, MRI, nuclear medicine, molecular imaging, optical, ultrasound, endoscopy, macroscopic and micro-scopic imaging, and multi-modality technologies.

LIVE DEMONSTRATIONS WORKSHOPA workshop featuring real-time demonstrations of algorithms and systems will be held during the conference. This workshop is intended to be a forum for developers to exhibit their creations, fi nd new collaborators, and inspire the attend-ees. All participants of SPIE Medical Imaging are invited to submit a proposal for a demonstration. More information will be provided at a later date.




Image-Guided Procedures, Robotic Interventions, and Modeling (MI104)Conference Chairs: Ziv R. Yaniv, Children’s National Medical Ctr. (USA); David R. Holmes III, Mayo Clinic (USA)Program Committee: Purang Abolmaesumi, The Univ. of British Columbia (Canada); Wolfgang Birkfellner, Medizinische Univ. Wien (Austria); Alexandre X. Falcão, Univ. Estadual de Campinas (Brazil); Baowei Fei, Emory Univ. (USA); Gabor Fichtinger, Queen’s Univ. (Canada); George J. Grevera, Saint Joseph’s Univ. (USA); Steven L. Hartmann, Medtronic Navigation (USA); David R. Haynor, Univ. of Washington (USA); William E. Higgins, The Pennsylvania State Univ. (USA); Pierre Jannin, Univ. de Rennes 1 (France); David M. Kwartowitz, Clemson Univ. (USA); Lena Maier-Hein, German Cancer Reserach Ctr. (DKFZ) (Germany); Michael I. Miga, Vanderbilt Univ. (USA); Kensaku Mori, Nagoya Univ. (Japan); Maryam E. Rettmann, Mayo Clinic (USA); Frank Sauer, Siemens Corp., Corporate Technology (USA); Guy Shechter, Philips Healthcare (USA); Eric J. Seibel, Univ. of Washington (USA); Robert J. Webster III, Vanderbilt Univ. (USA); Jay B. West, Accuray, Inc. (USA); Ivo Wolf, Hochschule Mannheim (Germany); Kenneth H. Wong, Virginia Polytechnic Institute and State Univ. (USA)

This conference is primarily concerned with applica-tions of medical imaging data in the engineering of therapeutic systems. Original papers are requested in the following topic areas:

• 3D visualization • Augmented, virtual, and enhanced reality • Mathematical modeling to guide and

understand therapy • Techniques in population-specifi c and patient-

specifi c model generation • Image-based models for characterization of

tissue and disease properties • Novel interfaces for therapy and visualization of

data • Image-guided procedures • Minimally invasive surgery • Computer-assisted therapy and therapy

planning • Robotic interventions and surgical tools • Medical image based simulation • Localization technologies and navigation

systems • Tracking and calibration • Intraoperative imaging • Intraoperative patient-to-image/-model

registration • Modeling of intraprocedural changes • Validation/evaluation • Telemedicine systems and their applications • Clinical applications and technology integration • High performance computing for real-time

modeling and/or large dataset visualization • Modeling and analysis of procedures • Safety and standards for image-guided and

robotic procedures • Other related areas.

Papers from student authors are particularly en-couraged; there is a competition for the best student paper and limited student travel awards are also available. Submissions that cross over between this conference and others at SPIE Medical Imaging, and which would be appropriate for combined sessions, are also welcomed.


TOPIC AREAS: For this conference onlyDuring the submission process, you will be asked to choose no more than three topics from the following list to assist in the review process.• Abdominal Procedures • Calibration • Cardiac Procedures • Pelvic Procedures • Diagnosis • Disease Characterization • Localization and Tracking Technologies • Endoscopic Procedures • Enhanced Reality • Image-Guided Therapy • Data Integration for the Clinic/OR • Intraoperative Imaging • Medical Robotics • Modeling • Monitoring and Feedback • Multimodality Display • Neurosurgical Procedures • Registration • Segmentation • Surgical Simulation • Therapy Planning • Treatment Planning • Ultrasound Guidance • Validation/Evaluation • Visualization • Human Factors • Stereoscopic Display • Other (please specify)



Call for Papers

Image Perception, Observer Performance, and Technology Assessment (MI105)Conference Chairs: Claudia R. Mello-Thoms, The Univ. of Sydney (Australia), Univ. of Pittsburgh (USA); Matthew A. Kupinski, College of Optical Sciences, The Univ. of Arizona (USA)Program Committee: Craig K. Abbey, Univ. of California, Santa Barbara (USA); François O. Bochud, Lausanne Univ. Hospital (Switzerland); Jovan G. Brankov, Illinois Institute of Technology (USA); Alastair G. Gale, Loughborough Univ. (United Kingdom); Howard C. Gifford, Univ. of Houston (USA); Stephen L. Hillis, Univ. of Iowa (USA); Elizabeth A. Krupinski, The Univ. of Arizona (USA); Maciej A. Mazurowski, Duke Univ. (USA); Anthony J. Maeder, The Univ. of Western Sydney (Australia); Mark F. McEntee, The Univ. of Sydney (Australia); Subok Park, U.S. Food and Drug Administration (USA); David L. Wilson, Case Western Reserve Univ. (USA); Federica Zanca, UZ Leuven (Belgium)

This conference focuses on a broad understanding of medical image perception, observer-performance measurement, and the application of these meth-ods to evaluation of medical technology. Areas of traditional interest include, but are not limited to, optimizing image acquisition, display and worksta-tions, psychophysical and vision-science based models of human observer performance, factors that affect the diagnostic process, eye-movement studies, observer performance methodologies, human-computer interaction, optimal decision-making strategies, statistical models for evaluation of observer performance, and observer variability assessment. The conference welcomes new areas of research as well. Original papers and posters are requested in the following areas:

• Technology assessment • Diagnostic-performance evaluation

methodologies (ROC, FROC and alternatives) • Observer performance evaluation of new

technologies (Acquisition devices, CAD, display devices etc.)

• Cognitive aspects of image interpretation • Perceptual and performance factors in

diagnostic workstation and environmental design

• Perceptual and performance factors in new modalities (e.g., digital pathology and telemedicine)

• Models of detection, discrimination, and localization

• The nature of reader expertise • Sources of observer variance


TOPIC AREAS: For this conference only To assist the reviewers, choose up to three keywords in order of relevance from the following list.• Image Display • Image Perception • Observer Performance Evaluation • ROC Methodology • Model Observers • Technology Assessment • Technology Impact • Other (please specify)

Critical DatesAbstract Due Date: 12 August 2013





Biomedical Applications in Molecular, Structural, and Functional Imaging (MI106)Conference Chairs: Robert C. Molthen, Medical College of Wisconsin (USA); John B. Weaver, Dartmouth Hitchcock Medical Ctr. (USA)Program Committee: Amir A. Amini, Univ. of Louisville (USA); Thorsten M. Buzug, Univ. zu Lübeck (Germany); Juan R. Cebral, George Mason Univ. (USA); Yu Chen, Univ. of Maryland, College Park (USA); Anne Clough, Marquette Univ. (USA); Alejandro F. Frangi, The Univ. of Sheffi eld (United Kingdom); Barjor Gimi, Geisel School of Medicine (USA); Andreas H. Hielscher, Columbia Univ. (USA); Xiaoping P. Hu, Emory Univ. (USA); Xavier Intes, Rensselaer Polytechnic Institute (USA); Andrzej Krol, SUNY Upstate Medical Univ. (USA); John F. LaDisa, Marquette Univ. (USA); Armando Manduca, Mayo Clinic College of Medicine (USA); Erik Leo Ritman, Mayo Clinic College of Medicine (USA); Merryn H. Tawhai, The Univ. of Auckland (New Zealand); Nicholas J. Tustison, Univ. of Virginia (USA); Axel Wismüller, Univ. of Rochester (USA)

This conference will cover all aspects of measuring and quantifying molecular, structural and functional parameters from biomedical images. Descriptions of work based on any imaging technology, includ-ing multidimensional and multimodality, are invited. Techniques, methods, and systems for evaluation and interpretation of structure-function relation-ships and interrelationships from images of intact, living tissues, are of particular interest. Work in emerging areas such as novel contrast agents, small animal imaging, optical or electrical impedance tomography, and dual-modality imaging is also of specifi c interest. Original papers are requested in, but not limited to, the following areas:

• Imaging methods, processing, analysis, registration

• Preclinical imaging, small animal imaging, molecular imaging

• Multimodality imaging, hybrid imaging • Nanoparticle, biosensors and magnetic particle

imaging (MPI) • Optical, electrical impedance, terahertz or

microwave imaging • Pulmonary structure and function: perfusion,

ventilation, mechanics, and modeling • Vessel and airway imaging: detection, modeling,

trees, reactivity, blood fl ow, perfusion • Cardiac structure and function: perfusion,

modeling, electrophysiology • Functional neuro-imaging and brain mapping,

fMRI • Magnetic resonance imaging (MRI) • Soft tissue imaging: deformation, quantifi cation,

analysis • Breast imaging • Bone and skeletal imaging: micro-structure,

orthopedic, fi nite-element models • Biomechanical imaging and modeling • Nuclear medicine: PET, SPECT, molecular

breast imaging (MBI), scintigraphy • Novel physiological imaging agents/

probes: quantum dots, nanoparticles, radiopharmaceuticals

• Physiologic modeling: metabolism, receptor-ligand binding

• Pharmacokinetic models


TOPIC AREAS: For this conference only During the submission process, you will be asked to choose no more than three topics from the following list to assist in the review process. • Physiological modeling / computational physiology • Novel imaging methods • Optical imaging • Vascular imaging • Breast imaging • Electrical impedance, terahertz or microwave

imaging • Imaging agents/molecular probes: receptor-ligand

binding / pharmacokinetic models • Magnetic particle imaging (MPI) • Nanoparticle imaging: sensing/therapy • Neuro-imaging, brain mapping, fMRI • Bone and skeletal imaging, biomechanics • Image processing, detection, segmentation,

registration, perception, analysis • Cardiac imaging and cardiomechanical modeling • Pulmonary structure & function: perfusion,

ventilation, mechanics, and modeling



Ultrasonic Imaging and Tomography (MI108)Conference Chairs: Johan G. Bosch, Erasmus Univ. Rotterdam (Netherlands); Marvin M. Doyley, Univ. of Rochester (USA)Program Committee: Jeffrey C. Bamber, The Royal Marsden NHS Foundation Trust (United Kingdom); Jan D’Hooge, Katholieke Univ. Leuven (Belgium); Neb Duric, Delphinus Medical Technologies, Inc. (USA); Stanislav Y. Emelianov, The Univ. of Texas at Austin (USA); James F. Greenleaf, Mayo Clinic (USA); Michael F. Insana, Univ. of Illinois at Urbana-Champaign (USA); Jørgen Arendt Jensen, Technical Univ. of Denmark (Denmark); Roman G. Maev, Univ. of Windsor (Canada); Stephen A. McAleavey, Univ. of Rochester (USA); Nicole V. Ruiter, Karlsruher Institut für Technologie (Germany); K. Kirk Shung, The Univ. of Southern California (USA); Kai E. Thomenius, General Electric Co. (USA); William F. Walker, Univ. of Virginia (USA)

The paper you present will live far beyond the conference roomAll proceedings from this event will be published in the SPIE Digital Library, promoting breakthrough results, ideas, and organizations to millions of key researchers from around the world.

www.SPIEDigitalLibrary.org

Helping engineers

and scientists stay

current and competitive


This conference provides a forum for in-depth dis-cussion of all aspects related to medical ultrasound imaging: physics of ultrasound wave propagation, image reconstruction strategies, hardware and system design, new imaging modalities, contrast agents, biological and biomedical applications of new ultrasound modalities. In addition, the 2014 conference will put special emphasis on acoustic microscopy (methodology, technology, application). A joint session with the Image-Guided Proce-dures, Robotic Interventions, and Modeling con-ference will be held in order to have a high-level discussion on the state-of-the-art in ultrasound guidance of surgical interventions.

TOPIC AREAS: For this conference onlyDuring the submission process, you will be asked to choose no more than three topics from the following list to assist in the review process.• Physics and computer simulation • Transducers and beam forming • Novel imaging approaches • Ultrasound tomography • Acoustic microscopy • Ultrafast imaging • Ultrasound image analysis • Ultrasound functional imaging • Motion and deformation estimation • Elastography • Contrast imaging • Tissue characterization • Photoacoustic imaging • High frequency imaging • New applications of ultrasound in medicine and

biology • Other (please specify)

Call for Papers



PACS and Imaging Informatics: Next Generation and Innovations (MI107)Conference Chairs: Maria Y. Law, Hong Kong Sanatorium and Hospital (Hong Kong, China); Tessa S. Cook, The Univ. of Pennsylvania Health System (USA)Program Committee: William W. Boonn, The Univ. of Pennsylvania Health System (USA); Thomas M. Deserno, RWTH Aachen (Germany); Steven C. Horii, The Univ. of Pennsylvania Health System (USA); Heinz U. Lemke, Computer Assisted Radiology and Surgery (Germany); Brent J. Liu, The Univ. of Southern California (USA); Eliot L. Siegel, Univ. of Maryland Medical Ctr. (USA); Jianguo Zhang, Shanghai Institute of Technical Physics (China)


Rapid developments implementation of picture archiving and communication systems (PACS) and related imaging and healthcare information management systems. The continued emphasis on system integration, workfl ow and globalization of information management has led to a need for more sophisticated imaging informatics techniques. In addition, the role of imaging informatics is bridg-ing gaps between the diagnostic and therapeutic realms. A new generation of PACS that accommo-dates other imaging-rich clinical specialties beyond radiology is a new focus this year. The conference will include, but is not necessarily limited to, the following general session topics:

Advanced PACS-Based Radiology Workfl ow and Image SharingWith the advent of thin-slice volumetric imaging, the need for research in more effi cient methods to analyze and navigate through large volumes of crucial clinical data becomes more apparent. Clinical experiences, workfl ow issues, systems performance, multimodality image display and navigation, new intelligent display technologies as well as sharing of images within a regional area will be discussed in this session.

PACS: Clinical Applications Beyond Radiology Images are used in multiple clinical specialties in addition to radiology. This new topic covers information management in the digital operating room as well as imaging in other clinical specialties such as pathology, dermatology and cardiology, to name a few. Suggested topics include but are not limited to: surgical workfl ow, digital operating room ergonomics, therapy imaging and model manage-ment systems, PACS, DICOM and IHE in surgery and other imaging-rich specialties, management and assessment of OR systems integration and architecture of ORs and imaging suites.

New Generation of PACS PACS is often designed for image storage and trans-fer within radiology or a hospital. With its extended utilization in different clinical areas and research such as bioimaging and bioinformatics, a new generation of dedicated PACS is worth resesarching that takes storage for research data and veterinary images for small animals into consideration. Also images from PACS are often being integrated with electronic health records. New and innovative con-cepts and technologies of PACS for such purposes will be discussed in this session.

Imaging and Information Exchange with Mobile Devices This session includes the application of cloud com-puting technology in imaging informatics related to healthcare and the use of mobile devices in radiol-ogy. Suggested topics include distributed image processing, design, implementation, and challenges in cloud storage architecture as well as mobile ap-plication development, security and networking challenges, mobile display performance, and imag-ing workfl ow performance utilizing mobile devices.

Information Management, Systems Integration and StandardsIntegration of radiology-based imaging with the electronic medical record and multimedia informa-tion from other specialties can positively impact the diagnostic and treatment process but must meet demands for enterprise-wide access and distribu-tion of image-intensive data. In addition, enterprise-level PACS design and implementation, extending to all clinical areas and patient care settings, can be achieved through the utilization of standards such as DICOM and HL-7 along with a number of IHE initiatives. This section will also cover topics includ-ing fault tolerance, data security and data integrity. Research developed utilizing DICOM-SR and other imaging informatics standards (eg, XML, HTML, XDS, etc) will also be covered within this session.

Quantitative Analysis, Data Mining and Image-based Patient-Specifi c Data ModelingLarge collections of reference images with reliable ground truth meta-information are required for comprehensive evaluation of image processing algorithms as well as for generation of reference models. Novel research aims at building patient-specifi c models, where individual morphology or function is integrated into the model. Although such data collections are used already in contests and applications, research is required to automatically generate and maintain such collections from PACS. Research in database development, database ag-gregation and knowledge base development will be covered along with data mining tools, such as content-based image retrieval (CBIR) methodolo-gies and the development of other tools to mine data. Medical imaging search related topics includ-ing web-, local-, and image-based search engines, indexing, ranking algorithms and NLP integration will be included.

Imaging Informatics for Diagnostic and Therapeutic ApplicationsDICOM provides a data-rich standard for image data that can be used for various diagnostic, therapeutic and rehabiliation applications. DICOM integration within radiation oncology, optical imaging and pa-thology in addition to research advancement in the utilization of DICOM-RT objects will be included in




Call for Papers

this session. Topics relating to research work per-formed based on DICOM WG26 are encouraged as well. Image-intensive diagnostic and therapeutic applications (e.g., surgery, radiation therapy, che-motherapy, and rehabilitation) will be discussed in this session.

Imaging Informatics for Medical and Biomedical Translational ResearchThis session will discuss the extension of imaging informatics to translational research. Research advancements toward personalized medicine will be investigated from genomic-related imaging in-formatics to small animal imaging to functional and/or whole body imaging and any imaging informatics tools developed to link various fi elds of research.

Managing Imaging Biomarkers and Image-Based Surrogates in Clinical TrialsImaging has become a key issue in controlled clinical trials. Endpoints of studies are defi ned on quantitative measurements extracted from images. However, PACS and electronic data capture (EDC) systems still appear disconnected, in particular providing insuffi cient support of multi-center trials. Based on existing standards for communication, ap-plied research is required to implement transparent interconnection for data and information exchange between such systems, which must be conformant with data privacy and security requirements.

Quality and Patient Safety Issues in Imaging InformaticsResearch on business intelligence and applica-tions for quality and patient safety within imaging informatics, including radiation dose monitoring and tracking, productivity and effi ciency, and other performance metrics and integration of CAD and PACS, will be discussed in this session.

TOPIC AREAS: For this conference only During the submission process, you will be asked to choose no more than three topics from the following list to assist in the review process: • Advanced PACS-Based Radiology Workfl ow and

Image Sharing • PACS Clinical Applications Beyond Radiology • New Generation of PACS • Imaging and Information Exchange with Mobile

Devices • Information Management, Systems Integration and

Standards • Quantitative Analysis, Data Mining and Image-

Based Patient-Specifi c Data Modeling • Imaging Informatics for Diagnostic and Therapeutic

Applications • Imaging Informatics for Medical and Biomedical

Translational Research • Managing Imaging Biomarkers and Image-Based

Surrogates in Clinical Trials • Quality and Patient Safety Issues in Imaging

Informatics





Digital Pathology (MI109)Conference Chairs: Metin N. Gurcan, The Ohio State Univ. Wexner Medical Ctr. (USA); Anant Madabhushi, Case Western Reserve Univ. (USA)Program Committee: Selim Aksoy, Bilkent Univ. (Turkey); Andrew H. Beck, Harvard Medical School (USA), Beth Israel Deaconess Medical Ctr. (USA); Rohit Bhargava, Univ. of Illinois at Urbana-Champaign (USA); Ulysses G. Balis, Univ. of Michigan Health System (USA); Eric Cosatto, NEC Labs. America, Inc. (USA); Andinet Enquobahrie, Kitware, Inc. (USA); Michael Feldman, The Univ. of Pennsylvania Health System (USA); David J. Foran, Univ. of Medicine & Dentistry of New Jersey (USA); Brandon D. Gallas, U.S. Food and Drug Administration (USA); Marios A. Gavrielides, U.S. Food and Drug Administration (USA); Stephen M. Hewitt, National Institutes of Health (USA); Jason Hipp, National Cancer Institute, NIH (USA); Elizabeth A. Krupinski, The Univ. of Arizona (USA); Richard M. Levenson, Univ. of California, Davis (USA); Olivier Lezoray, Univ. de Caen Basse-Normandie (France); Derek Magee, Univ. of Leeds (United Kingdom); Anne L. Martel, Sunnybrook Research Institute (Canada), Univ. of Toronto {Canada); Erik Meijering, Erasmus Univ. Medical Ctr. (Netherlands); James P. Monaco, VuCOMP (USA); Tim W. Nattkemper, Univ. Bielefeld (Germany); Nasir M. Rajpoot, Univ. of Warwick (United Kingdom), Univ. of Qatar {Qatar); Badrinath Roysam, Univ. of Houston (USA); Berkman Sahiner, U.S. Food and Drug Administration (USA); John E. Tomaszewski, Univ. at Buffalo (USA); Darren Treanor, Univ. of Leeds (United Kingdom), Leeds Teaching Hospitals NHS Trust {United Kingdom); Martin J. Yaffe, Sunnybrook Research Institute (Canada); Bulent Yener, Rensselaer Polytechnic Institute (USA)

This conference will address digital pathology, from acquisition of pathology data to its management, analysis, and interpretation by observers. The use of digital pathology data, by both the human and computer, is growing in importance with the recent advent of whole slide scanners and novel instru-mentation for multispectral, multiparametric tissue imaging. There is potential for digital pathology to improve diagnosis and grading of cancer and other pathology tasks, but there are still limitations and challenges that must be addressed before it can be incorporated in the clinical workfl ow. Although there has been great progress in the development and application of digital pathology over recent years, there are a number of signifi cant computational challenges specifi c to pathology imaging that distinguish it from its radiological counterpart. There are also unique challenges in terms of how digitized pathology specimens and correlated data are presented to, modifi ed and interpreted by clinicians. We invite submissions that address specific problems related to image acquisition, computer-aided diagnosis, and quantitative image analysis of pathology specimens. We particularly welcome contributions that identify and address challenges encountered in digital pathology imaging as well as in new approaches for image capture and analysis.

TOPIC AREAS: For this conference only.During the submission process, you will be asked to choose no more than three topics from the following list to assist in the review process.

Image Acquisition• Acquisition, storage, and processing of microscopy

images, including histopathology, cytology, immunohistochemistry, and immunofl uorescence,

• Image mosaicking of nontraditional near-real-time microscopy (OCT, confocal)

• Multispectral imaging • Multi-focus volume imaging

Quantitative Image Analysis• Computer-aided diagnosis and prognosis • Automated quantifi cation of tissue biomarkers • Grading and classifi cation of pathology images • Segmentation of cellular and tissue structures • Shape analysis and morphology in pathology

imaging • Architectural feature extraction and quantifi cation • Multispectral- and volume-based segmentation • Content-based image retrieval, machine-learning,

semantic annotation, and visualization of pathology image databases

• High-performance computing for whole-slide tissue image analysis

Information Fusion• Radiology-pathology registration and fusion • Registration of multiply stained tissue microscopy

images • Integration of digital image features with “omics”

data for fused diagnostics

Others• Color normalization • Remote consultation • Metrics, variability and standardization issues

unique to digital pathology • Methodologies for the objective technical

assessment of digital pathology systems • Observer performance, human factors and

diagnostic interpretation issues • Optical probe tracking and visualization tools • PACS and new DICOM standards for

histopathology • Other (please specify)






VenueTown & Country Resort and Convention Center500 Hotel Circle NorthSan Diego, CA 92108 USAThe Town & Country Resort and Convention Center features 1,000 guest rooms spread over 40 lushly landscaped acres in San Diego’s Mission Valley. Three swimming pools, full service spa and health club, barber and beauty services, in-room movies, valet and room services, and a complimentary morning newspaper are available to each guest! Located in the heart of Mission Valley, the Town & Country Resort is ideally situated for attendees and their guests to enjoy the many adjacent and nearby attractions.

RegistrationSPIE Medical Imaging registration will be available October 2013All participants, including invited speakers, con-tributed speakers, session chairs, co-chairs, and committee members, must pay a registration fee. Authors, coauthors, program committee members, and session chairs are accorded a reduced sympo-sium registration fee. Fee information for conferences, courses, a regis-tration form, and technical and general information will be available on the SPIE website in October 2013.

Hotel InformationOpening of the hotel reservation process for SPIE Medical Imaging 2014 is scheduled for the begin-ning of October 2013. SPIE will arrange special discounted hotel rates for conference attendees. The website will be kept current with any updates: www.spie.org/micall

Student Travel GrantsA limited number of SPIE student travel grants will be awarded based on need. Applications must be received no later than 9 December 2013. Eligible applicants must present an accepted paper at this meeting. Offer applies to undergraduate/graduate students who are enrolled full-time and have not yet received their PhD.

SPIE Scholarship ProgramInformation is available online at: www.spie.org/scholarships

Clearance InformationIf government and/or company clearance is required to present and publish your presenta tion, start the process now to ensure that you receive clearance if your paper is accepted.

Important News for All Visitors from Outside the United StatesFind important requirements for visiting the United States on the SPIE Medical Imaging website. There are steps that ALL visitors to the United States need to follow.Online at: www.spie.org/visa

General Information

Conference Sponsorship Opportunities

SPIE would like to express its deepest appreciation to the symposium chairs, conference chairs, program committees, session chairs, and authors who have so generously given their time and advice to make this symposium possible.

The symposium, like our other conferences and activities, would not be possible without the dedicated contribution of our participants and members.

This year’s SPIE Medical Imaging conference sponsorships provide a unique opportunity to interact with the leading professionals in the fi eld and gain high-profi le visibility before, during, and after the event.

Interested in sponsoring an event, advertising with SPIE? Learn more:

Contact Al Ragan, +1 360 685 5539 · Fax: +1 360 647 1445 or [email protected]

www.spie.org/mi14sponsor

Sponsor Packages:‘Gold’ Sponsor Level – $5000 (2 Available)‘Silver’ Sponsor Level – $2000 (5 Available)

Event Specifi c SponsorshipsStudent Networking Luncheon $2,500 (Exclusive)Best Student Paper $1,250 (Exclusive)Poster Sessions $1,250 (Exclusive each day)Workshops $1,250 (Exclusive)Conference Sponsor $1,250 (Exclusive, one sponsor per conference)Conference Bags 1,$500 (Exclusive)

Advertising OpportunitiesPrint and Web Ads The prices are 25% lower than traditional SPIE program

advertisement pricing. Web advertising pricing varies.


Each conference review committee recognizes a selected poster at the cum laude level for best poster presentation in their conference. Congratulations to the following who received this award in 2013.

NOTE: Papers accepted in the program and presented during the poster session are eligible for award consideration.

Congratulations to the 2013 Poster Award Winners

Participate in a Poster SessionGain valuable feedback and one-on-one networking with colleagues.

Physics of Medical Imaging Biomedical Applications in Molecular, Structural, and Functional Imaging

Pressure distribution on mammography compression of breasts containing breast cancerPaper 8668-158Authors: Daniel Förnvik, Magnus Dustler, Ingvar Andersson, Håkan Brorson, Pontus Timberg, Sophia Zackrisson, Anders Tingberg, Lund Univ. (Sweden)

Reduced centrality of Wernicke’s area in autismPaper 8672-78Authors: Caspar J. Goch, Klaus H. Fritzsche, Jan Hering, Bram Stieltjes, Deutsches Krebsforschungszentrum (Germany); Romy Henze, UniversitätsKlinikum Heidelberg (Germany); Hans-Peter Meinzer, Deutsches Krebsforschungszentrum (Germany)

Image Processing Image Perception, Observer Performance, and Technology Assessment

3D seam selection techniques with application to improved ultrasound mosaicingPaper 8669-158Authors: Jason F. Kutarnia, Peder C. Pedersen, Worcester Polytechnic Institute (USA)Note: Only student papers are considered for theaward in this conference.

Prediction of near-term breast cancer risk using a Bayesian belief networkPaper 8673-50Authors: Bin Zheng, Pandiyarajan Ramalingam, Harishwaran Hariharan, Univ. of Pittsburgh (USA); Joseph K. Leader, UPMC Presbyterian (USA); David Gur, Univ. of Pittsburgh School of Medicine (USA)

Computer-Aided Diagnosis Advanced PACS-based Imaging Informatics, and Therapeutic Applications

Curved planar reformation and optimal path tracing (CROP) method for false positive reduction in computer- aided detection of pulmonary embolism CTPAPaper 8670-115Authors: Chuan Zhou, Heang-Ping Chan, Yanhui Guo, Jun Wei, Lubomir M. Hadjiiski, Baskaran Sundaram, Smita Patel, Jean W. Kuriakose, Ella A. Kazerooni, Univ. of Michigan Health System (USA)

An intelligent monitoring and management system for cross-enterprise biomedical data sharing platformPaper 8674-29Authors: Tushen Wang, Yuanyuan Yang, Jianguo Zhang, Shanghai Institute of Technical Physics (China)

Image-Guided Procedures, Robotic Intervention, and Modeling Ultrasonic Imaging, Tomography, and Therapy

Transorbital target localization in the porcine modelPaper 8671-63Authors: Michael P. DeLisi, Louise A. Mawn, Robert L. Galloway, Vanderbilt Univ. (USA)

Development of a 3D ultrasound system to investigate post-hemorrhagic hydrocephalus in pre-term neonatesPaper 8675-58Authors: Jessica Kishimoto, Robarts Research Institute (Canada) and Lawson Health Research Institute (Canada); Sandrine de Ribaupierre, The Univ. of Western Ontario (Canada); Aaron Fenster, Robarts Research Institute (Canada); Keith St. Lawrence, Lawson Health Research Institute (Canada); David Lee, The Univ. of Western Ontario (Canada)

Digital Pathology

An adaptive image representation learned from data for cervix cancer tumor detectionPaper 8676-25Authors: Angel Cruz Roa, Eduardo Romero Castro, Fabio González Osorio, Univ. Nacional de Colombia (Colombia)


Congratulations to the 2013 Student Paper Award Recipients

2014 Student Paper Awards InformationATTENTION STUDENTS

Below are the submission instructions and eligibility requirements for the 2014 Student Paper Awards.

Submissions Due: 16 December 2013

The winners of this award will be students: • without a doctoral degree • who are the principal authors of the paper in the current program • selected by the review committee.

A fi rst place winner and runner-up will be recognized with a cash prize and a certifi cate during the plenary session at the meeting. To be considered, students must submit electronic copies of: • the full manuscript to the Conference Programs Coordinator ([email protected])

- no later than 16 December 2013. • a signed letter from the student’s advisor stating that the principal contribution to the

work described was made by the student.

NOTE: This manuscript will be used for review purposes only. A separate manuscript must be submitted for publication by the manuscript due date.

The best student paper award was presented to:Pankaj Daga, Univ. College London (United Kingdom)

Susceptibility artefact correction by combining B0 fi eld maps and non-rigid registration using graph cuts . . . [8669-10]

Congratulations to the Runners Up of the Best Student Paper AwardKe Li, Univ. of Wisconsin School of Medicine and Public Health (USA)

How to determine detection performance of a DPC-CT system from a conventional cone beam CT system? . . . . . . . [8668-35]

Asha Singanamalli, Case Western Reserve Univ. (USA)

Identifying in vivo DCE MRI Parameters Correlated with ex vivo Quantitative Microvessel Characteristics: A Radiohistomorphometric Approach . [8676-3]

NOTE: Students with accepted papers in the program are eligible to enter the Best Student Paper competition. Full papers must be submitted by the 16 December 2013 due date.


Submission of Abstracts

By submitting an abstract, I agree to the following conditions: An author or coauthor (including keynote, invited, oral, and poster presenters) will:• Register at the reduced author registration rate (cur-

rent SPIE Members receive an additional discount on the registration fee).

• Attend the meeting.• Make the presentation as scheduled in the program.• Submit a full-length manuscript (6 pages minimum)

for publication in the SPIE Digital Library, Proceed-ings of SPIE, and CD-ROM compilations.

• Obtain funding for their registration fees, travel, and accommodations, independent of SPIE, through their sponsoring organizations.

• Ensure that all clearances, including government and company clearance, have been obtained to present and publish. If you are a DoD contractor in the USA, allow at least 60 days for clearance. .

Submit an abstract and summary online at www.spie.org/micall • Please submit a 250-word text abstract for technical

review purposes that is suitable for publication. SPIE is authorized to circulate your abstract to confer-ence committee members for review and selection purposes.

• Please also submit a 100-word text summary suit-able for early release. If accepted, this summary text will be published prior to the meeting in the online or printed programs promoting the conference.

• Identify the topics appropriate to the specifi c con-ference. During the submission process you will be asked to choose no more than three topics from a predefi ned list and/or add a topic not included on the list. (See individual conference Call for Papers for topic categories.)

• Prepare your 2-4 page supplemental MS Word or PostScript fi le. Supplemental fi le instructions can be found online. For full consideration this fi le must include the paper title, authors, 250-word abstract text, and the following supplemental information: - Description of purpose - Method(s) - Results - New or breakthrough work to be presented - Conclusions - Whether the work is being, or has been, submitted

for publication or presentation elsewhere, and, if so, indicate how the submissions differ.

- This fi le may contain supporting images/tables/fi gures

- Failure to follow these guidelines may disqualify your submission.

• Only original material should be submitted.• Abstracts should contain enough detail to clearly

convey the approach and the results of the research.

• Commercial papers, papers with no new research/development content, and papers where support-ing data or a technical description cannot be given for proprietary reasons will not be accepted for presentation in this conference.

• Please do not submit the same, or similar, abstracts to multiple conferences.

Review, Notifi cation, and Program Placement Information• To ensure a high-quality conference, all submissions

will be assessed by the Conference Chair/Editor for technical merit and suitability of content.

• Conference Chair/Editors reserve the right to reject for presentation any paper that does not meet con-tent or presentation expectations.

• The contact author will receive notifi cation of ac-ceptance and presentation details by e-mail no later than 11 October 2013.

• Final placement in an oral or poster session is sub-ject to the Chairs’ discretion.

Proceedings of SPIE and SPIE Digital Library Information• Manuscript instructions are available from the “For

Authors/Presenters” link on the conference website. • Conference Chair/Editors may require manuscript

revision before approving publication and reserve the right to reject for publication any paper that does not meet acceptable standards for a scientifi c publication. Conference Chair/Editors’ decisions on whether to allow publication of a manuscript is fi nal.

• Authors must be authorized to transfer copyright of the manuscript to SPIE, or provide a suitable publication license.

• Only papers presented at the conference and received according to publication guidelines and timelines will be published in the conference Pro-ceedings of SPIE and SPIE Digital Library.

• Published papers are indexed in leading scientifi c databases including Astrophysical Data System (ADS), Chemical Abstracts (relevant content), Com-pendex, CrossRef, Current Contents, DeepDyve, Google Scholar, Inspec, Portico, Scopus, SPIN, and Web of Science Conference Proceedings Citation Index, and are searchable in the SPIE Digital Library. Full manuscripts are available to SPIE Digital Library subscribers worldwide.

When submitting your manuscript to the pro-ceedings, we encourage you to consider also submitting it to the SPIE peer-reviewed Journals, Journal of Biomedical Optics (JBO) and Journal of Electronic Imaging (JEI). Manuscripts submitted to these journals will go through the normal peer-review process. No reformatting is necessary for initial submission to the journals, but manuscripts intended to be reviewed must adhere to the gen-erally higher standards of content required of a refereed journal. For more information, please visit the Author Information at www.spie.org/journals




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