2016 Corporate Report

What is Leitat?

Leitat is a Technological Institute with the mission of collaborating with companies and other entities to create economic, social and sustainable value by R&D+2i projects and technology processes from innovation and creativity. Leitat is the brand of the private entity Acondicionamiento Tarrasense and is recognized by the Catalan Government (TECNIO) and by the Spanish Ministry of Science and Innovation

Who does Leitat belong to?

Leitat is a private non-profit association of industrials with own legal and patrimonial capacity established in 1906. Leitat performs its activity according to the current legislation, its articles of association and its Internal Regime Rules.

What does Leitat contribute?

Leitat, from dynamism and proximity, provides flexible management in an open innovation environment as collaboration and cooperation driving force for technology transfer and promoting the principles of professionalism, respect for people and environmental care, at the same time.

Why does Leitat improve competitiveness at industrial level?

Because Leitat promotes the implementation of industrial innovation strengthening modernization of the productive structures and the development of new high technology value products and meets the changing needs of the global market.

How can Leitat solve the technological needs?

Thanks to its technology solvency, Leitat keeps creating knowledge, developing talent and acquiring high technology equipment and facilities, so that the specific and technology needs of our customers can be met.

Why does Leitat perform in many different sectors?

Because this allows that many technologies are applicable in different sectors obtaining more profitability of technology, generating and broadening new opportunities even in sectors never before interconnected and focusing its activity on these sectors: Transport, Building, Packaging, Textile, Energy, Environment, Food, Cosmetics, Detergency, Sport, Health, Pharmacy, Chemistry and Materials, Security and Sea sector.

How does Leitat collaborate with companies and institutions?

Leitat from experience and flexibility, by signing collaboration agreements to join efforts to meet the industrial technology challenges set out and promoting enterprising capacity and technology transfer.

Which is Leitat experience in industrial cooperation?

For more than 100 years ago, Leitat impacts on companies and other entities through the management of R+D+2i proposals (research, development and industrial innovation) leading or participating in strategic projects and generating actives and knowledge.

Which is the geographical ambit of action?

As well as acting at domestic level, Leitat actively leads and participates in many projects and international collaboration nets including European partners and others from other areas with convergent interests.

How become part of Leitat?

Any individual or corporation may become partner of Leitat by making a formal request on the webpage:

www.leitat.org/socio

FAQ In Leitat, innovation means meeting industrial technology challenges with efficiency and efficacy.

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Origin

Recent History

Organization

Current time

Promoting collaboration

Connected to knowledge networks

Value proposal

Multisectorial answers

Knowledge divisions

R+D+2i initiatives

Notified Inspection Body

Advanced Technology Solutions

Leitat undertakes

Summary of 2015 activities

Featured Events

R+D+2i Projects

Feedback from our customers

Leitat figures

Our commitment

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OriginIn 1906, a group of industrialists concerned about quality, certification and research in the wool textile sector decided to found a supporting association for competitiveness of companies named Acondicionamiento Tarrasense. Those industrialists knew how to anticipate needs for business collective solutions and laid the foundations of the current concept of Leitat

Over the years and thanks to the work performed, the entity evolved both to the extension of its activities and to the name that is currently identified with the brand known as Leitat.

During these years, our vocation in offering services to companies and entities has remained unchanged, whereas the activities developed, the organization and our internal work system have changed significantly specializing in different knowledge areas allowing the search for the best technology solutions for companies.

The results obtained lately show that the bet developed by Leitat towards knowledge generation and transfer to the productive fabric is an effective model for economic growth in a fast, efficient and sustainable way, creating at the same time new areas and models for talent development and personal performance for all employees.

Origin

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ORGANIZATION

Board of Directors The Board of Directors on December 1st, 2015, was comprised by the following members:

Acondicionamiento Tarrasense is a non-profit entity, with legal status and own assets, incorporated in 1906. The company governs its activities according to Law 4 / 2008, dated on April 24, of the third book of the Spanish Civil Code on legal persons (DOGC number 5123, May 2), the Organic Law 1 / 2002 of March 22, regulating the right of association (BOE 73, March 26) and its Articles

KNOWLEDGE DIVISIONS Human & Environmental Health & Safety Sustainability Advanced Materials BiomedDevices, Design & EngineeringEnvironmental & Bio TechnologiesTribology & Metal ProcessingFast Moving Consumer Goods

ADVANCED TECHNOLOGY SOLUTIONSSCIENTIFIC AND TECHNICAL SERVICES

Characterization of materials

R+D+2i INITIATIVESBIPCNBSS

NOTIFIED BODYCertifications of personal protective equipment (PPE) and building materials

INNOVATIONInnovation and New Technologies

STRATEGIC AND SUPPORTING STRUCTUREFinance and Administration Industrial Cooperation Corporate DevelopmentOrganization and Strategic Planning People Development and Management Project ManagementIntegrated Management Systems (Quality, Environment and Occupational Hazards Control) General Services Information Systems

President:Mr Eusebi Cima MolletRepresentatitive of E-CIMA S.A.U

Vice-president 1st: Mr Jordi William Carnes AyatsRepresentative of LEADING ADVANCED TECHNOLOGIES INVESTMENT, S.L.U.

Vice-president 2n: Mr Joan Parra FarréRepresentative of FUNDACIÓN PARA LA DESARROLLO Y LA INNOVACIÓN TECNOLÓGICA

Secretary:Mr Josep Armengol Giralt Representative of the INDUSTRIAL INSTITUTE OF TERRASSA

Member:Mr Salvador Maluquer TrepatRepresentative of COTTON PROCESSING TEXTILE INDUSTRIES ASSOCIATION

Member:Mr Francesc Roca i LlonguerasRepresentative of FINISH, S.A.

Member:Mrs Dolors Puig GasolRepresentative of EUNCET FORMACIÓN, S.L.

Organization chart From a traditional structure to a flexible and dynamic organization. We focus on work teams and projects based on cross-communication and definition of responsibilities with the goal of meeting the technological expectations of customers and society.

GOVERNING BODIES:The Association consists of 7 associate members coming from several complementary industrial sectors and business asso-ciations.

The General Assembly is the major and sovereign body of the entity in which all members are represented.

The Board has the authority to represent, lead and manage the Association. This body also implements the decisions taken by the General Assembly, in accordance with the regulations, instructions and guidelines established.

From the flexibility and agility that our customers require, we give answer with our value proposal, adapt to the market needs and promote the change to encourage the technology entrepreneurship, support the open innovation with large and SMEs, leader outstanding projects and strengthen the international collaboration as value of the technology networking, acting in this way as a unifying vehicle between market and research.

In collaboration with innovative companies and entities, and together with an extensive list of ambitious projects, we are joining efforts to research and be more open to a global and competitive market from creativity, innovation and learning. Our experience, stable and strong, enables us to keep on promoting industrial innovation focused on transforming technology challenges value with Social, Environmental, Economic and Industrial impact.

Thanks to our entrepreneurship and proactive attitude, together with our leadership capacity, we constantly challenge the status quo and search technologic solutions providing the company competitive advantage and growth. We focus our energy on promoting specialized teams in Technology Transfer, allowing the generation of collaborative and reliable business environments to reach an economy based on knowledge and talent development.

On this Corporate Report, we want to share and reflect the activities carried out in 2015, still in a very complex situation. These results are obtained from the strength of our attitude and availability, commitment, involvement and responsibility of all the employees that are part of Leitat. With our work, and attentive to our stakeholders (clients, partners, associated and society), clients, partners, collaborators, suppliers, public administration, partnerships and society) we keep on strengthening our institutional vocation of service to companies, entities and society, overcoming technology and economic challenges and respecting all the time our principles and values from the Excellence in management.

Hoping we keep on making progress, we remain at your disposal..

Best regards,info@leitat.org Mr. Eusebi Cima - PresidentDr. Joan Parra - General Manager

CURRENT TIMECURRENT TIMEMANAGING TECHNOLOGIES

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Mr. Eusebi CimaPresident

Dr. Joan Parra General Manager

MAIN NATIONAL ORGANIZATIONS

MAIN INTERNATIONAL ORGANIZATIONSLeitat takes part and works as

a technology partner in several initiatives that demonstrate its reliability as a dynamic agent for technology transfer and innovation planning in companies, entities and institutions, through different national and international organizations:

ORGANIZATIONS: 48 SPANISH 29 INTERNATIONAL

PROMOTING COLLABORATION

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MAIN INTERNATIONAL ORGANIZATIONS

MAIN SPANISH TECHNOLOGY PLATFORMS

MAIN EUROPEAN TECHNOLOGY PLATFORMS

CONNECTED TO KNOWLEDGE

NETWORKSRecognizing that intellectual property is universal and it is developed and strengthened anywhere in the world, Leitat strongly believes and promotes the concept of "Open Innovation" as force of collaboration to provide an effective response to the technology challenges posed by customers.

PLATFORMS:28 SPANISH 24 EUROPEAN

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MANAGING TECHNOLOGIESOur work is marked by flexible management and we are oriented to meet technological demandsof our clients

CollaborationParticipation in R+D+2i projects by providing knowledge and experience, with economical and social return.

CooperationWe cooperate to create sustainable and innovative value and globally respond with competitiveness

DynamismWe have a good organizational structure to be able to offer fast and efficient solutions that are adaptable, responsible and transparent.

ProximityWe establish good communication with our environment with a global perspective, confidentiality and commitment.

WE GIVE ANSWER with our value proposal

MISSIONCreate and transfer economic, social and sustainable value to companies and entities, through research and technology processes.

VISIONBe a benchmark in the sector, creating a corporative culture that enables sustainable growth and efficiency of actions.

CORPORATIVE CULTURE

Principles:

CREATIVITY

INNOVATION

SUSTAINABILITY

ENVIRONMENTALLIABILITY

DIVERSITY

EFFICIENCY

EFFICACY

Values:

DYNAMISM

INDEPENDENCE

COMMITMENT

CUSTOMERORIENTATION

CONFIDENTIALITY

GLOBAL PERSPECTIVE

TALENT

ENVIRONMENTTRANSPORT SECTOR HEALTH

PACKAGINGTEXTILE SECTOR ENERGY

COSMETICS PHARMACY BUILDING

SECURITYCHEMISTRY AND MATERIALS SPORTS

DETERGENCY

FOOD

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SEA SECTOR

MULTISECTORIAL SOLUTIONS to the technology needs of companies

PROCESS IMPROVEMENTPRODUCTS IMPROVEMENTCHANGE ADAPTATIONINNOVATION CAPACITYCOMPETITIVE IMPACTSOCIAL IMPACTINTERNATIONALIZATIONECONOMIC RETURN

TRANSPORT SECTORBUILDINGPACKAGINGTEXTILE SECTORENERGYENVIRONMENTFOODCOSMETICSDETERGENCYSPORTSHEALTHPHARMACYCHEMISTRY AND MATERIALSSECURITYSEA SECTOR

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TRANSPORT

Advanced Materials (polymers, adhesives, coating, nano)Advanced Production Systems, CAD, CAE, design and simulation Smart systemsElectromobility, batteries and supercapacitors, alternative energy Support to industrialization and testing

BUILDING

Advanced Materials (asphalts, cementos, nano)Smart systems and Smart CitiesEnergy Efficiency Smart integration of renewable energy

PACKAGING

Design, FEA and implementation of conceptsNew materials: polymers, adhesives and nanomaterialsTransformation and printing pilot processesInks and printed electronics Global support to industrialization, testing and products validation

TEXTILE SECTOR

New materials for technical textiles (biomaterials)Development of inks, finishing and application of nanotechnology Spinning, weaving and finishing processes to pilot processes Smart textiles, support to industrialization and testing

ENERGY

Third generation solar cells Lithium and post_Lithium batteries and supercapacitors Energy harvestersStudies on energy efficiency

ENVIRONMENT

Treatment of wastewater and sensors of emerging pollutants Air treatment Valorisation of organic and mineral waste Studies on ecotoxicityNanosecurityLife cycle assessment and carbon footprint

FOOD

Functional food (screening, cellular models, bioavailability) Micro-capsulation of ingredients and active principles Food security New proteins

COSMETICS

Nanomaterials and nanocapsules Formulation of cosmetic products Test on consumers

DETERGENCY

Study and development of new ingredients Formulation and efficiency tests of products Test on consumers Applied microbiology

SPORTS

Prevention, diagnosis and treatment of muscle and tendon injuries Stem cellsMetabolomics and genetic studies Design and sports teams Physiological studies of top sportsmen New technical textiles Formulation of products of sports hygiene

HEALTH

BiosensorsMetabolomicsNanosecurity and nanotoxicologyMedical devices and textiles Social welfare

PHARMACY

New therapeutic targets New cellular models Biomedicine Nanomedicine Drug discovery and development

CHEMISTRY AND MATERIALS

Synthesis of nanomaterials and polymers Formulation of polymers, paints, coatings, asphalt and concretes Surface treatmentsNanosecurity , REACH Testing, analytical chemistry and accompaniment to industrialization

SECURITY

Design and validation of personal protective equipment Nanosecurity Sensors and actuatorsStudies on efficiency and toxicity

SEA SECTOR

Marine monitoring, marine sensors, detection and quantification of pollutants. Bioprospecting / bioproduction of marine natural products.“Smart” materials and recyclability, technology and treatment of surfaces, personal protection equipments. Marine organisms and microorganisms, screening for identifying active principles.Safety and sustainability (analysis & biosensors for detecting infections, toxicological studies). New solutions for designing personal care and home products (detergents, cosmetics) to reduce the marine impact.

KNOWLEDGE DIVISIONS Industrial research adding value, differentiation and innovation opportunities in the global markets.

Multidisciplinary teams with know-how and experience in different knowledge areas and disciplines.

HUMAN & ENVIRONMENTAL HEALTH & SAFETY (HEHS) SUSTAINABILITYADVANCED MATERIALS (AM)BIOMEDDEVICES, DESIGN & ENGINEERING (D2E)ENVIRONMENTAL & BIO TECHNOLOGIES (EBT) TRIBOLOGY & METAL PROCESSING (TMP)FAST MOVING CONSUMER GOODS (FMCG)

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HUMAN & ENVIRONMENTAL HEALTH & SAFETY (HEHS)

Research lines:

• Nanosecurity.

• Nano(eco)toxicology.

• Nanoencapsulation for therapeutic use and diagnosis.

• Security and efficiency of drugs, cosmetics and food additives.

• Bioanalytics and metabolic.

• Substance risk assessment / nanomaterials / additives.

• Exposure assessment.

• Advice on REACH and CLP.

The safety and sustainability area focuses its activity on providing technological support and advising to different industrial sectors in order to ensure that facilities, processes and products are safe. The technological support and advising offered for the different levels is:

Technological support:

• Monitoring and evaluation of emissions/release of NM of a product throughout all the stages of the life cycle (characterisation and quantification of emissions through highly sensitive techniques).

• Evaluation of NP risk and impact on the human health, particularly in the pharmaceutical, cosmetic and food industry fields: in vitro toxicological studies (feasibility, oxidative stress, genotoxicity, inflammation, irritation) in vitro biokinetics in cellular models with different levels of complexity and in vivo studies (biodistribution, histopathology) in rodent models.

• Bioanalytics and metabolomics services for in vitro and in vivo studies using high resolution analytical techniques (chromatography combined with mass spectrometry).

• Assessment on the risk of substances, emerging contaminants, metals and nanoparticles: ecotoxicological studies in the terrestrial and aquatic compartments; transport monitoring and transformation of nanoparticles in the terrestrial and aquatic compartments (including design of the sampling method and characterisation with highly sensitive equipments). Toxicology studies and assessment on the occupational and environmental exposure.

• Design and production of nanoparticulate systems (nanocapsules) for the vehiculation of active ingredients dermal and oral delivery, mainly for application to medicine and cosmetics.

• Design and production of metal nanoparticles for application to biosensors.

Advising:

• Legal-technical advising on environmental regulations and industrial safety: REACH, CLP. Diagnoses, drafting of registration files, action plans.

• Development of exposure scenarios and risk characterisation in the life cycle of the product.

• Training and awareness.

• Conducting trials required by REACH, determination of SVHC in items.

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ADVANCED MATERIALS (AM)

Research lines:

• Processes of synthesis of polymers and biopolymers, nanoparticles, nanofibres and micro and nanocapsules.

• Formulation of raw materials through pilot processes as composites, nanocomposites and biocomposites extrusion, electrospinning, preparation of inks, coatings and paints, concrete mixture processes and stabilized products.

• Application of new materials by new techniques such as injection, blow moulding, inkjet, screen printing, padding and plasma and sun-gel treatments.

Global and optimized projects for the development of new materials aimed at the main industrial sectors as transport, building, energy, packaging, consumer goods, aeronautics and textile, and focused on 4 great pillars:

• Nanotechnology.

• Polymers and polymeric composites.

• Surface technology.

• Inorganic materials of the building sector.

We perform integral projects in the sector of the science of materials covering the whole scale of values and different phases of the productive processes: synthesis phases, formulation of raw materials with pilot tests and realization of technology demonstrators applied to the new materials developed, as well as studies on recyclability and useful life of new materials. By doing so, we try to help the industry to develop their projects from any stage of the value chain of the materials with the aim of providing knowledge and innovation and creating an industrial network in the field of materials and industries to apply the new products and processes developed.

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SUSTAINABILITY

Leitat brings innovative solutions to complicated environmental issues and transform them into opportunities of competitive improvement.

Research lines:

• Sustainable Production:

We give response to companies to promote efficiency, resources optimization, prevention, waste minimization, management and valuation, sustainable mobility, etc. to face the new industrial panorama with success and security.

• Energetic audits on processes, installations and facilities.

• Studies on waste minimization and viability for the assessment of generated waste.

• Industrial symbiosis.

• Business models based on Circular Economy.

• Mobility plan of companies, studies on sustainable mobility.

• Ecodesign and Life Cycle Assessment:

Incorporation of environmental criteria in the design of products, services and processes to reduce negative environmental impact along their life. Quantification of environmental impact from the obtaining of raw materials through production, use and end of life as a waste.

• Life Cycle Assessment (LCA) of a product, service and package.

• Ecodesign of a product, productive process.

• Calculation of carbon footprint.

• Green shopping, greening of events.

• Ecolabel and Environmental Communication:

Voluntary tools so that the organization reaches high level of environmental protection and a commitment for continuous improving.

• Environmental Communication strategy of the organization.

• European Union Ecological Label (EU Ecolabel) for products and services.

• Distinctive of Environmental Quality Guarantee of the Catalan Government (DGQA).

• Environmental statement of the product, environmental information based on ACV.

• Environmental Management Systems according to the European Regulation EMAS and the International Standard ISO 14.001, Energy Management UNE-EN 16.001, Ecodesign Management ISO 14.006.

• Memory of Sustainability, Actions of Social Responsibility.

• Workshops and training courses on good environmental practices.

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BIOMED

Research lines:

• Generation of polyclonal and monoclonal antibodies (mAb) made to order for basic research, diagnosis and treatment.

• Genetic engineering of monoclonal antibodies: Antibody Drug Conjugates (ADC), Single domain antibodies (Nanobody), Bispecific Antibodies, Chimerization, Humanization, fusion proteins, Antibody fragments (Fab, scFv), and Biosimilars.

• In vitro cellular models to study efficiency, action mechanisms, screening, synergies, etc. (oncology, inflammation, angiogenesis).

• In vitro animals models to study efficiency, biodistribution, pre-Tox MTD, pre-PK, histology, etc (oncology, inflammation, angiogenesis and severe and chronic pain).

• Design of biogenomic tools for the validation of therapeutic targets and biomarkers diagnoses: siRNA, hairpins of DNA, arrays analysis, etc.

Aimed at therapy and diagnosis of oncology, inflammatory, autoimmune and angiogenic diseases with activity in the areas of:

• Analysis of therapeutic effectiveness of new drugs, whether chemical, biologic or genetic (at molecular, biochemical, immunochemical, cellular level, and in laboratory animals).

• Drug-targeting and drug-delivery projects for drugs improvement and other therapeutic applications.

• Development of new biologic drugs (monoclonal antibodies and recombinant proteins) and improvement of these drugs (quimerization, humanization, biosimilars, conjugation).

• Identification, assessment and characterization of new therapeutic targets and diagnostic biomarkers.

• Determination of new indications for commercialized drugs and in clinical phases (reprofilling).

• Development of new and innovative tools for diagnosis, prognosis and monitoring of the evolution of diseases and their treatment (monoclonal antibodies, ELISA kits and Immunohistological kits).

• Development of devices for outpatient use (lateral flow devices, biosensors). Our diagnostic solutions and the specific biosensors are applicable in different industrial sectors as health, veterinary, food and environment.

DEVICES, DESIGN & ENGINEERING (D2E)

Research lines:

• Devices: design, manufacture, characterization and development of new applications for sensors, biosensors and telecommunication antennas.

• Enertronics: design, assembling and characterization, control and integration of devices and energy systems (photovoltaic, energy storage, thermoelectricity and combustible batteries).

• Advanced manufacture processes: composites processing, robotics, additive fabrication, printed electronics and ionic liquid technology.

• Design and development of product and process by tools of industrial design, simulation and multiphysics modelling.

Innovation in products and processes meeting the needs of different sectors as textile, telecommunications, health, energy, transport or environment, and focused on:

• Technology research.

• Industrial design and development.

Thanks to a multidisciplinary team grouped by physicists, chemists, mathematicians, electrochemists and engineers, we can develop innovative projects from different perspectives. We also have laboratories especially equipped to develop these activities.

• Electronics laboratory.

• Additive manufacturing laboratory.

• Energy laboratory.

• Equipments for manufacturing, assembling and printing devices.

• Equipments for solar simulation and electrochemical characterisation.

• Equipments for processing and characterising composites.

• CAD/CAE/CAM design tools.

• Software for multiphysics simulation.

• Useful life and pre-approval trials for accelerated ageing.

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ENVIRONMENTAL & BIO TECHNOLOGIES (EBT)

Research lines:

• WATER: Treatment, sanitization, reuse, assessment.

• WASTE: Treatment, material/energy assessment.

• INDUSTRIAL BIOTECHNOLOGY AND APPLIED MICROBIOLOGY: Biocatalysis, bioprocesses, bioadditives, new strains, biofilms.

Sustainable and innovative technology for an efficient management of the natural resources (water and raw materials), air pollution, treatment and assessment of waste from different origin, and the incorporation of biotechnology and bioprocesses in the industrial sector, at laboratory and/or pilot scale.

Specific removal of pollutants, maximum reuse of WATER and recovery of high added value products or energy through:

• Electrochemical processes and advanced oxidation processes.

• Membrane technology and new selective materials/nanomaterials.

• Biologic/bioelectrochemical processes.

Technology sequential combination for the assessment of the vector WASTE allows the material maximum recovery, energy conversion and the obtaining of new products or bioproducts thanks to an integral strategy applicable to biomass and mix or complex municipal and industrial waste:

• Mechanical, chemical, physical-chemical, thermal and biotechnological / bioelectrochemical technologies.

Chemical analysis and sensory control of the AIRE vector, together with strategies of pollutants removal inside or outside:

• Photocatalytics, physical-chemical, biologic processes.

Application of INDUSTRIAL BIOTECHNOLOGY for obtaining more efficient and innovative processes and bioproducts:

• Bioprocesses, biocatalysis and bioelectrochemical system for obtaining active bioproducts.

• Utilization of enzymes as functional additives in Fast Moving Consumer Goods formulations.

MICROBIOLOGY APPLIED in the industrial environment:

• Obtaining and improving new microbial consortia with high capacity to degrade pollutants or produce high added value bioproducts.

• Application of biofilms: models for forming and obtaining biomaterials; models of complex microbiota.

• Alternative antimicrobials and models for validating antimicrobial activities.

TRIBOLOGY & METAL PROCESSING (TMP)

Leading team with proven expertise in Tribology and Tribochemistry, focused on the formulation of cutting fluids.

Studies on stability of products from the Tribochemistry sector and other products from the machinery-tools sector, including the concentrated product and the emulsion in water of different degrees of hardness. There is also available a set of equipment to study lubricity, corrosion, wear protection and foaming capacity fulfilling the most demanding international standards, DIN and ASTM.

Speciality in foaming studies simulating the real conditions of use in the industry for a wide range of processes in the manufacturing industry, as well as stability tests in saline and climatic chamber to assess the stability of metallic pieces to corrosion.

Screening and assessment of raw materials alternative to the conventional cutting fluids. Use of biodegradable materials with low impact on environment, in line with green manufacturing, as the use of biomaterials and the processes with lower energy consumption.

Selective treatments of multi metal surfaces, washing and cataphoresis, followed by the most demanding performance studies and quality in the metallic finishing.

Selective use of experiments design as useful tool to detect the correlation between different parameters and the desired answer by the client.

FAST MOVING CONSUMER GOODS (FMCG)

Research lines:

• Solutions in the design of detergent, cosmetic and food products by innovative formulations, optimizing those already existing and incorporating new raw materials added value to products.

• Efficiency tests based on standards or new tests adapted to the needs of our customers showing the efficiency of the products.

• Specialization in Ecolabel, detergent assessment reports, general cleaning and healthcare products as well as cosmetic products.

• Tests on consumers, smelling assessment and custom-made tests helping communication strategy.

Specialization in detergents for clothing care, surfaces, hand and automatic dishwashers for the industrial sector (industrial and home) of consumer goods (industrial and home) as well as development and assessment of new cosmetic products.

The stability, microbiological, enzymatic activity, toxicity and in vitro security tests complement the solutions for the companies of Home & Personal Care supported by our knowledge in textiles, materials and surfaces.

Integral development of projects regarding food technology, considering the different phases: study of the raw materials, formulations, manufacturing process, sensory assessment and useful life of the product. Specialization in functional food. Improvement and optimization of formulations with the aim of achieving “cleaner labels” with natural ingredients.

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Fotografía_Laboratorio_fuente_Archivo_Leitat

BIPBarcelona Institute of Packagingwww.barcelonapackaging.org

Program supporting companies on innovation and development of packaging projects and offering technical advice on industrial implementation, searching the best synergies of the R+D equipment and the product engineering of Leitat.

Activities:• Product Packaging Engineering. Development of new

projects of Packaging (CAD-CAM-CAE). From Design to Industrialization.

• Studies on industrial viability of new projects of packaging.

• Technical validations and testing. Assessment of new designs, new materials and compatibility of product-package. Analysis and assessment of the essential parameters in all kind of packages and packaging, from the mechanical to the physicochemical properties.

• Packaging re-engineering. Re-designs, optimization and standardization projects to improve efficiency and behaviour in the production lines. OCB cost reduction programs OCB (Optimal Cost Balance).

• Packaging and Logistics. Projects on logistics effectiveness. Logistic validations. Tests and assessment on storage and transport. Codification and identification.

• Services of processes homologation, new machinery for packaging and conditioning of products according to the international acceptance criteria for new machinery and processes.

• Ecodesign in Packaging. Transitional projects to the sustainable design of Packaging. Life cycle analysis. Environmental re-engineering.

• Support to training. The Program has the academic support of the University Politècnica of Catalonia on the training and recycling of engineering and technicians capable of leading the new challenges of the packaging engineering sector, package and conditioning of products within the framework of the current Master in Packaging Engineering and its specialization courses.

CNBSSCentro de NanoBioSeguridad y Sostenibilidadwww.cnbss.eu

Common initiative by Leitat and the Catalan Institute of Nanotechnology (ICN) created in 2009 with the following goals:• Develop new tools and methods to determine the safe

and rational use of the nanomaterials in the products along their life cycle. Quantifying the risk and the environmental impact will facilitate the acceptation of the innocuous nanoproducts by the market, accelerate their acceptation by society and investment return.

• Develop new, safe and sustainable applications of nanoscience and nanotechnology in a wide range of fields, including environmental improvement, drugs administration, energy, new semiconductors, building and food. It includes the development of the metrology as a key tool to facilitate the normalization and efficient regulation and standards elaboration.

• Promote the use of solutions based on nanotechnology applied in strategic sectors through activities as training, education and dissemination, approaching nanotechnology to industry.

In 2010, the Centre received initial funding by the Catalan Government and the Spanish Ministry of Science and Innovation (MICINN). Since then, both Leitat and ICN have been working on:

• Wide range of technical services and products. • Observatory of best practices and regulation. • Search of applied research. • Creation of a platform of resources for experts. • Creation of a platform to the dissemination and

training for the general public.

R+D+2i INICIATIVES

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NOTIFIED BODYLeitat is the Notified Inspection Body no. 0162, authorized by the Ministry of Industry, Commerce and Tourism for the performance of the Conformity Assessment (Marking EC) of Personal Protective Equipment according to the regulation 89/686/EEC, as well as quality control assessment of finished products (Article 11A) for personal protective equipment of category III, which offer protection against serious risk or danger. Also for building materials, according to the European directive 305/2011 system 3.

Recognized laboratory by the International Automobile Federation to perform testing on protective clothing and gloves for pilots according to standard FIA 8856-2000.

Recognized laboratory by CIK-FUI for the homologation of karting suits.

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Materials behaviour• Physical, mechanical, thermal, chemical and

microbiological• Microscopic and colorimetric characterisation • Climate ageing –radiation-corrosion

Analytical chemistry• Development of analytical methods• Wastewater analysis• Identification and characterisation of polymers and

additives • Identification and characterisation of loads and stresses• Identification and characterisation of VOCs substances

anresidual substances (VOCs, formaldehyde) • Carbon emission (automotive industry) • Formaldehyde emission (automotive industry) • Fogging of condensable components (automotive industry)• Global and specific Migration studies• Nanoparticles analysis• Elemental analysis (N,C, O, H y S)• Biodegradability analysis• Traces of water analysis (Karl Fisher)• Analysis of pollutants in air• Analysis of biogas• Analysis of sugars, anions and volatile fatty acids

Quality control• Product assurance• Process assurance• Supply Chain Management

Validation of prototypes• Materials• Finished products• Industrial processes

EU-EcolabelTests and verification of assessment reports of environmental criteria for:• Textile products• Cleaning products in general • Laundry detergent• Detergents for industrial washing • Detergents for dishwashing• Detergents for industrial dishwashing • Detergents for hand dishwashing • Cosmetics (rinse needed)• Soap and shampoo• Paints and varnishes• Furniture• Lubricants• Paper• Tourist accommodations• Campings

Characterization of materials Application of new technologies• Plasma• Polymer extrusion• Rapid Prototipe – 3D Impression

Three-dimensional metrology (in laboratory or in situ)• Metrology of pieces: homologation reports of moulds and dies• Measurement and reports with the CAD comparative method• Dimensional study on assembling faults• Measurement of samples, statistic reports and process control• Automatic measurement programs for measurement equipment by

coordenates• Digitalization and reverse enginery

Fire behaviour• Tests for materials aimed at textile architecture• Tests for protective equipment against heat and flame• Recognition by the Ministry of Public Works for the certification of

security products against fire (aviation)• Recognition by Iberia for the certification of products for security

against fire (aviation)

Bioanalysis and health• Antibacterial and antifungal activity of actives, materials and

formulations• Models of formation and elimination of biofilms• Studies on microtoxicity and water microbiological control• Tests on enzyme activity• Studies on cosmetics security and efficacy (BPL)• Efficacy test of preservatives in cosmetics (Challenge Test)• Studies on security for detergency products • Studies on security for medical devices• Studies on biodisponibility and alimentary allergenicity• Studies on absorption, distribution, metabolism, excretion and toxicity

of medicaments (ADMEtox)• Bioequivalences (BPL)• Metabolomic analysis in vitro/ in vivo (GLP)• Studies on the efficiency of antitumor compounds (in vitro and in vivo)• Studies on the efficiency of potential drugs against autoimmune

diseases causing inflammation (in vitro and in vivo)• Generation of poli and monoclonal antibodies to be used in research,

diagnosis, prognosis and therapy.• Design and development of biosensors diagnoses• Antibodies engineering: humanization and chimerization nanobodies,

scFv, bi-specific, ADCs, fusion proteins, Biosimilars• Drug reprofiling

TECHNICAL CAPACITYBecause of its vocation to multisector service, Leitat constantly updates to provide latest technology in order to perform characterization and behavior of materials, targeted at a wide range of sectors.

ADVANCED TECHNOLOGY SOLUTIONS SCIENTIFIC AND TECHNICAL SERVICES

LEITAT UNDERTAKESEntrepreneurshipCreation, development and technology transfer with social implication in the new markets by identified needs of the markets or sectors.Financial and competitive support in the development of the project/product to guarantee its impact in the market and capitalizing technology development.

TECH MENTORINGTechnology transfer from knowledge generating cores. Complete use of technology and knowledge obtained from research. Creation of actives and abilities to customers (technology, brand and systems).

ADVANCED MANAGEMENTGlobal-market oriented strategic administration.Directive competences and abilities. Flexibility and adaptability.

GROWING BUSINESS AREAAccess to multisectorial equipment, using synergies with the Centre and in an Open Innovation environment to broaden the initiatives reach. Acceleration platform for internationalization. Complimentarity with other already extisting projects.

FFF COMMUNITYRelationship with financial funds and partners to facilitate and improve the company plans and the first stages of the Technology Based Companies (TBC) projects.Generation of critical mass for business development by promoting and developing projects focused on growth and business consolidation oriented to market success.

CONCEPTLABDefinition of concepts for products, services, processes and business models that are authentically and aimed at the market.

REORIENTATIONSearch of new activities allowing an approach to new management models.

INFORMACIÓN INFORMATION ON TECHNOLOGYImprove the technology level of products, services and processes. Use mechanisms to be able to find, evaluate and transfer external technological knowledge.

TRAINING AND TRANSFERDevelopment of generic training actions that are specified on technological topics and innovation management.

INNOVATION MANAGEMENTImplementation of a personalized model to improve innovative capacity.

PROCESSES IMPROVEMENT SYSTEMSImprovement of processes by using more efficient techniques and management

LEITAT INNOVATION

DESCRIPTION OF BUSINESS IDEA

ANALYSIS OF MARKET NEEDS VIABILITY

ECONOMIC ANALYSIS

SELECTION TEAM

OBJECTIVES

SCIENTIFIC SUPPORT

DEVELOPMENT IDEA

BUSS

INES PLAN

SPINOFF

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SUMMARY OF ACTIVITIES 2015

Creativity

Innovation

Learning

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Chemistry, Energy and Resources and sustainable Mobility.Leitat coordinates de Community of Health-Applied Technologies (TEC-SALUT) to promote innovation in the medical technologies within the ecosystem of innovation. The Community TEC-SALUT aims to create a collaboration and common work system within the health system meeting the needs and challenges of the different agents forming the health system. In this community, more than 110 members of the Catalan sanitary sector participate and the plan of action of the community is based on 4 projects focused on priority specialization areas of technologies imported to Health and sustainable partner-sanitary ecosystem. In the plan of action of 3 years length, there is the participation of entities such as Hospital Sant Joan de Déu, Hospital de la Vall d’Hebron, Terrassa Health Consortium, Parc Taulí, University Politécnica of Catalonia, Intelligent Pharma, IDNEO, EAP Centelles, etc. The total budget to carry out the plan of actions is 9M€ with 4,2M€ grant.

LEITAT ORGANIZED THE KICK OFF MEETING OF THE ALISE PROJECT

Leitat organized the kick off meeting of the ALISE Project (Advance Lithium Sulphur Batteries for Hybrid Electric Vehicle) in Barcelona, a collaborative ambitious project of 4 years length within the framework program Horizonte 2020. The event was the kick off for the collaboration of the 15 pan-European participating entities with the aim of developing innovative batteries by means of the lithium sulphur technology for the automotive sector. In the meeting, the research works to be performed in the first phases of the project were coordinated and intended to create great impact on the automotive sector. The ALISE project, with a budget of 6 M€, intends the demonstration of the viability of the lithium sulphur batteries for automation with a pilot test in a real car. This kick off meeting represents the way towards a more efficient Europe, improvement of competitiveness and the positioning of the European companies in the energy storage sector within the automotive industry.

ACEC AND LEITAT: INSTITUTIONAL COLLABORATION AGREEMENT

The presidents of the ACEC (Catalan Association of Consulting Companies) and Leitat, Joan Camprubí and Eusebi Cima respectively, signed an institutional collaboration agreement to develop common actions between both entities and the associated companies of ACEC. This is a strategic agreement of high importance since Leitat is in the leading-edge on innovation in the private sector. The event was attended by three members of the Advisory Committee of ACEC: Jordi Casas, Emilio Cuatrecasas and Jordi Hereu.

LEITAT OBTAINS THE SEAL EFQM 400+

Leitat renewed its seal of European Excellence (EFQM) reaching the 400+ points, which recognizes the excellence of its management system. This seal is the result of the work started years ago on the improvement of the management systems oriented at Excellence and, at the same time, the commitment to keep on working on efficiency and efficacy to reach new excellence and quality levels in all its structures. The Management Excellence Club (MEC) is a non-profit business association, founded in Spain in 1991, by twenty one first executives of the most important Spanish companies and Primary Partner of the European Foundation for Quality Management (EFQM) since 1994. The MEC is formed by 20 partners from a wide range of sectors, which nowadays represent the 26% GDP and 34% IBEX35. It intends strengthening the global competitiveness of organizers and professionals from different sectors through the values of excellence, and providing its partners infrastructure to share knowledge, develop abilities and give visibility to their excellence levels.

LEITAT LAUNCHES AN OPEN LABORATORY TO PROMOTE EXPERIMENTATION WITH ADDITIVE FABRICATION AMONG COMPANIES

According to the strategy of smart specialization in the Advanced Manufacture sector in Catalonia, Leitat has finished one of its most lengthily persecuted projects: the implementation of the Additive Manufacturing & 3D Printing Lab, the additive manufacturing and 3D printing laboratory. The goal is offering to the industrial fabric a high capacity tool that facilitates and strengthens the massive use of these technologies by the productive industry to obtain all advantages from their potential. This new additive manufacturing laboratory is divided into three zones depending on the topology of the materials to be processed and their presentation: metal powder, powdered and filament thermoplastics and photosensitive liquid thermostables. It is a particular laboratory because it is open to the industry of the country and Europe to research on new materials, benchmarking of assessment of the AM/3DP technologies for the production and development of new applications and post-processes and finishing of components obtained by additive manufacturing.

LEITAT LEADS THE COMMUNITY RIS3CAT “HEALTH-APPLIED TECHNOLOGIES, TEC-SALUT”

The research and innovation strategy for the smart specialization of Catalonia (RIS3CAT) defines the framework from which the Government develops the financing actions and programs of R+D+I for the period 2014-2020. In the first call 2015, ACCIÓ assigned 19.1 million Euros from the European Regional Development Fund (ERDF) to certify 5 Communities RIS3CATin the following sectors: two communities in the health industries and one in the following areas: Food,

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authorities chairing the event were the manager of the Medical and Performance Area of FC Barcelona, Jordi Monés, and the general manager of Leitat, Joan Parra. The event was supported by Fundación FCB, Fundación Leo Messi and the Catalan Government. MuscleTech is a worldwide referent project as meeting for researchers, doctors, physiotherapists and physical trainers, of acknowledged international prestige, to interchange, debate, publish and discuss the latest tendencies and innovations in the field of muscle and tendon lesions. This edition was attended by 450 international participants.

LEITAT HOSTS THE ANNUAL ASSEMBLY OF CLUSTER OF PACKAGING

Leitat actively participates in the policy of clusters, and it has defined as strategic the sector of packaging, locating in its facilities the Barcelona Institute of Packaging (BIP), the technology supplier in the field of packaging for companies. As member of the Board of Directors of the Cluster of Packaging, Leitat hosted the Annual Assembly of the cluster in its auditorium in Terrassa. The assembly was started by the welcome by the president of Leitat, Eusebi Cima, and the president of the cluster, Artur Costa, who stressed the importance of the packaging sector in the country. The cluster presented the incorporation of 10 new partners, four of which are big companies (Lecta Group, Lubrizol, KAO Chemicals and GCR Group), 4 SMEs (Decapulp, Cimworks, Sheet-Pack and Font Packaging Group) and 2 other members (IRTA and Amec). Among the activities realized, there are the relationships with other clusters and clients, which stimulate the demand of new innovative projects, training with the promotion of a new Packaging Engineering

LEITAT ORGANIZES THE VI WORKSHOP ON INNOVATION IN CATALONIA

The VI Workshop on Innovation in Catalonia celebrated in the auditorium of the facilities of Leitat in Terrassa was titled: Innovation – Engine for economy and competitiveness. Once again, this workshop reinforced the will of Leitat to be a benchmark in innovation, both at national and international level. In the event, Albert Giralt, general manager of Avinent; Artur Costa, general manager of Pyamsa; Carles Rua, manager of Strategic and Innovation Projects of the Port of Barcelona; Jorge Barrero, general manager of Cotec; Xavier Cañadó, manager of Companies of the Catalan Territory of Banc Santander; and Jordi Portabella, manager of the Research and Knowledge Area of the Fundación Bancaria la Caixa, gathered together to discuss on economy and the role of the administrations as engine for innovation. The first part dealt with issues as the company seen as an incubator to create new companies and the corporative entrepreneurship as the great opportunity for the companies to create them. The importance of innovation as one of the three points of the strategic model of a company was stressed out, as well as internationalization and specialized diversification. Finally, the participants talked about the sectors of greater innovation in the ports: security, information systems, operative efficiency, alternative fuels, sensorization and the transport models. The second part dealt with the view of innovation as a change based on knowledge generating value, noting eight tendencies to innovate: collaboration, entrepreneurship, reuse, commitment, ubiquity, limits, opening and speed. The Program Advanced was pointed out as a new form of innovation for business growth based on talent, internationalization, occupation and digital connectivity. There were also presented other tools as CaixaImpulse and the program RRI-TOOLS, based on the knowledge triangle (business, training and research), to which the society is incorporated to carry out responsible innovation and research.

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During the closing, the general manager of Leitat, Joan Parra, stressed that “we can innovate in all sectors, innovation cannot be automated and the sources, of all type, are key factors in the innovation processes”.

INTERNATIONAL LEITAT: CHILE, OUR FIRST IMPORTANT INTERNATIONALIZATION PROJECT

With the goal of contributing to the creation of value in the strategic sectors in Chile through innovation and technology, Leitat launched the International Center of Excellence in Nanotechnology (CEN) Leitat Chile on September 2015 in Santiago de Chile. The event was attended by authorities as the Vice-president of Corfo, Eduardo Bitrán, the General Manager of Leitat, Joan Parra, the Rector of the University Santiago de Chile, Juan Manuel Zolezzi, and the Ambassador of Spain in Chile, Carlos Robles. Fundación Leitat Chile supports CEN with the challenge of transforming technology research and development into specific services and products providing value, productivity and competitiveness to the sectors of the country traditionally based on natural sources. CEN is supported by the Program of Attraction of R+D International Centers of Excellence of Corfo and the leadership of Leitat, as well as the collaboration of the University Santiago de Chile, the University Autónoma of Barcelona, the University Politécnica of Valencia and the Knowledge Innovation Market (KIM) in Spain. The challenge of this ambitious project is to generate in Chile an industry of nanotechnologies companies to diversify production and sophisticate the companies of the national production system. This Center will operate in Chile with all experience in research and technology provided by Leitat.

7TH MUSCLETECH NETWORK WORKSHOP

The facilities of FC Barcelona, in Camp Nou, hosted the seventh annual meeting of MuscleTech Network, which this year coincided with the fourth Congress of ECOSEP ((European College of the Sport & Exercises Physicians). The meeting was organized by FC Barcelona, Aspetar, Ecosep and Fundación Leitat. The main

LEITAT AND THE COUNCIL OF VILANOVA DEL CAMÍ: II WORKSHOP ON INNOVATION OF L’ANOIA

The Workshop on the prospects of Innovation in l’Anoia was celebrated in the Anoia Innovation Center. The first part of the event had the participation of Vanessa González, Mayoress of Vilanova del Camí, Blai Paco, President of the UEA, Eusebi Cima, President of Leitat and Jaume Caterineu, President of TicAnoia. The introduction was carried out by Sergi Artigas, Manager of Strategy in Innovation of Leitat, who gave the lecture Innovation Opportunities. In the second part of the event, it was organized a panel discussion on Innovation, moderated by Marc Mañé from 2.0 TICAnoia, with the participation of Joan Dosrius from ABACUS, Paco Ortiz from PLANEXT, Lluís Pinardel from PIERA ECOCERÁMICA, Miquel Vila from CLÚSTER DE LA PELL and Jordi Solà from CUBUS GAMES, who discussed the visions of innovation of different companies and entities in the current scene. Antoni Castellà, Secretary of Universities and Research of the Catalan Government, closed the event. .

LEITAT, COMMITTED TO THE WEEK OF SUSTAINABLE AND SECURE MOBILITY

In the framework of the Week of Sustainable and Secure Mobility, Leitat organized a walk from the facilities in terrassa to Llac Petit in Can Bogunyà. This water reservoir, created to water sourcing of the fields of Can Bogunyà, forms artificial lake, s meeting point in contact with nature of the citizens of Terrassa at the beginning of 1900. During 1 hour and low difficulty level, the walk was taken under a relaxed and lively atmosphere, strengthening the after-work relationship among the staff of Leitat. This activity recalled the importance of doing physical activity for the well-being of people. Leitat, within the framework

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Postgraduate Course with the UPC as well as the generation of collaboration projects among the members of the cluster. Once selected the new members of the Board of Directors, it was organized an open day to other companies with a master class of “30 pieces of a management to SUPERvivir. The vision of the CEO 2015-2020”, given by Luis Soler, from Odgers Berndtson, and the Presentation of the Promotion Plan of the Food Industry, by Belén Tascón, from the Catalan Government.

LEITAT, MEETING POINT OF CATALAN COUNTRIES OF THE NET INNPULSO

Leitat hosted the first meeting of Catalan cities of the Net Innpulso, which gathers the cities of Spain that have obtained the distinction “City of Science and Innovation”, granted by the Ministry of Economy and Competitiveness (MINECO). The meeting was organized by the Council of Terrassa and Leitat within the collaboration framework between both entities and framed in the Parc Cientific i Tecnològic Orbital 40. The event was attended by Luis Cueto Álvarez de Sotomayor, Deputy Director of Business Innovation Promotion, of the General Direction of Innovation and Competitiveness of the MINECO. He focused on the presentation of the 2020 European Strategy and the financing resources for SMEs. In the event, representatives of different cities participated: Cerdanyola del Vallès, Sabadell, Sant Boi de Llobregat, Sant Feliu de Llobregat, Terrassa, Viladecans and Vilanova del Camí. These Councils presented the innovation state in their cities. During the event, they manifested that there are interesting financing opportunities for the Spanish SMEs until at least 2020, which will allow these companies to carry out innovation and research projects, largely financed by European funds. The event was followed by a “networking” session in which the local Administrations and the participating companies shared experiences and possible communication channels. The meeting ended with bilateral meetings between Leitat and the participant companies and between the different Councils and the Ministry of Economy and Competitiveness.

of its environmental policy, has a Guide of sustainable actions, which includes environmental criteria to minimize the environmental impact on the organization of events.

EXHIBITION OF THE CATALAN PRIZE ECODESIGN 2015 IN LEITAT

The Show-Room of Leitat hosted the travelling exhibition “Catalan Prize Ecodesign 2015”. This exhibition showed products, projects and strategies participating in the contest convened by the Office of Territory and Sustainability of the Catalan Government with the Waste Agency of Catalonia. The main goal of the contest was rewarding the proposals that, through the design, reduce the environmental impact along the whole life of the product, favoring better environmental behavior from the extraction of the raw matter through production, use and management as waste. The prize consisted of 5 categories: Product, Product in development, Strategy, young Design and Euro-Mediterranean Design. The exhibition gathered the winner applications as well as those that received a special mention by the jury.

R+D+2i OUTSTANDING PROJECTS ON INDUSTRIAL RESEARCH

Industrial innovation

Competitiveness

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NUEVAS DIANASDISCOVERY AND COMBINATION OF NEW THERAPIES FOR THE TREATMENT OF CANCER THROUGH THE MODULATION OF EPIGENETIC TARGETS AND ADENOSINE RECEPTORS"

The project intends the integration of the programs of pharmaceutical development of new targets aimed at the treatment of oncology diseases of Palobiofarma and Oryzon Genomics. The project tries to make progress in the researching lines of each one of the participating companies with the collaboration of participating Researching Bodies (USC-BioPharma and Leitat-Biomed) and also tries to explore a possible treatment combined between the epigenetic inhibitors developed by Oryzon and the inhibitors of andenosine receptors developed by Palobiofarma. The participation of USC and Leitat in the analysis and development of the compounds of both companies will allow an integral comparison of the results of the compounds of each one of the companies, which will help to firmly define and quantify the possible enhancer or synergic effects of a combination of compounds.

Contract number: RTC-2015-3332-1 Total Budget: 1.479.659,52 € Funding: 1.334.965,91 €Budget Leitat: 160.382,25 €

METASIN FUNCTIONAL ALIMENTATION AS NATURAL ALTERNATIVE TO THE METABOLIC SYNDROME’S TREATMENT, THE SO CALLED “21ST CENTURY EPIDEMIC”

The project METASIN’s main objective is to research and develop ready to market multifunctional active ingredients, foods and nutritional complements, which are able to have influence on the pathologies and risk factors associated to the metabolic syndrome. The aim is to improve the quality of life of the targeted population in an integral way. METASIN is a project consisting of a consortium of 8 Spanish industrial companies.

http://metasin.eu/Total Budget: 10.139.812,90 € Funding: 7.550.224,79 €Budget Leitat: 852.700,00 €

PROGRESOPROTEINS OF THE FUTURE: INNOVATIVE SOLUTIONS TO THE PROCESSING OF PROTEINS AND THEIR APPLICATION IN NEW FOOD PRODUCTS ADAPTED TO POPULATION GROUPS WITH SPECIFIC NEEDS

The project PROGRESO encompasses within a working common framework where different researching lines are related to the main goal, which is researching on technologies that allow obtaining high added food products that improve protein intake in food and that provide technical solution to the protein demand of population groups with specific needs. This project consists of 8 industrial partners from the sector.

Total Budget: 8.563.067 € Funding: 6.422.300 €Budget Leitat: 709.855 €

SMART FACTORY RESEARCHING ON ENABLING TECHNOLOGY OF SMART SYSTEMS FOR THE FACTORIES OF THE FUTURE

The project focuses on technology research for smart systems aimed to create the factories of the future. The vision of the project is a world highly automated and collaborative, where smart robotics combines its efforts with creativity and adaptation to persons. The project aims to take a substantial leap regarding the current state of the art, contributing to all the items of this vision. SMART FACTORY is a national level project and consists of 12 partners.

Total Budget: 7.465.728 € Funding: 5.599.296 €Budget Leitat: 446.000 €

GLUBAARESEARCH AND DEVELOPMENT OF NEW LUBRICANT, BIODEGRADABLE, SELF-EXTINGUISHING AND ANTI-VIBRATION FATS

The goal of this project is the development of new highly secure, biodegradable, self-extinguishing and anti-vibration industrial lubricant fats to be applied in railway installations, ski slopes or aquatic parks. This R+D project will last for two years and a new range of lubricant products will be developed with the aim of giving answer to the sectors where the use of mineral fats presents potential risk of fire or implicates high cost of maintenance due to cleaning or the need of applying the product constantly.

Contract number: RD15-1-0102Total Budget: 624.247,17 € Funding: 233.247,32 €Budget Leitat: 157.000 €

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ZITOMABDEVELOPMENT OF ANTI-TUMOUR SECOND GENERATION IMMUNOTHERAPIES: ANTIBODIES AND NANOBODIES CONJUGATED WITH TOXINS THROUGH INTEINS – ZIP

The project ZITOMAB will develop a new strategy of immunotherapy based on the last generation of conjugated antibodies and nanobodies. This innovative strategy will allow the access to inner zones of the solid tumour, which are inaccessible up to now. For this purpose, there is the experience and technology of the companies ZIP solutions, which provides its inteins technology, Althia health, which provides knowledge in the production of owning antibodies as well as histopathology analysis and two important public research centers: IRB Barcelona, which will provide its knowledge on peptides and cytotoxic synthesis, and Leitat, which will provide its knowledge both on antibodies, animal models and research on the leading technology of Nanobodies.

Contract number: RTC-2015-4336-1Total Budget: 926.362,80 € Funding: 724.988,13 €Budget Leitat: 199.500 €

RECOVER ANTI-POLLUTION INTEGRAL SUSTAINABLE TREATMENT FOR THE CREATION OF GREEN RAIL CORRIDORS

The goal of the project RECOVER is the creation of Green Rail Corridors, by removing or mitigating the pollution associated to the development of these infrastructures mainly to heavy metals and hydrocarbures. The project intends the generation of a zone free of pollution coming from the circulation of trains in the railways and surroundings, which will allow environmental improvement of these railways and near areas. Leitat will participate in the project by developing sol-gel based ballast coating and phytoremediation and bioremediation processes to treat grounds adjacent to railways. The results will favor the legislative development concerning the decontamination of grounds at national and European level. Funding of the project was granted in 2015 within the call Challenges-Collaboration by the Ministry of Economy and Competitiveness. The project will be carried out by the partners COMSA, CETIM and Leitat.

Contract number: RTC-2015-4043-4Total Budget: 779.442 € Funding: 419.168,22 €Budget Leitat: 230.147,20 €

IMMEDANTI-TUMOR AND ANTI-METASTATIC ACTIVITY OF MONOCLONAL ANTIBODIES IN ANIMALS MODELS OF HUMAN CANCERS

The project IMMED has been encouraged by a consortium consisting of the company Immunological and Medicinals Products and two world-renowned centers: the Foundation for the Biomedical Research of the Hospital Universitario de la Princesa (FIBHULP) and Leitat. Immunological and Medicinals Products is a company with wide experience in the development of therapies and methods of molecular diagnoses for oncology and inflammatory and autoimmune diseases. IMMED will participate in the pre-clinical and functional assessment of the leads antibodies. The center FIBHULP will participate in the in vitro tests of the antibodies union. Leitat will participate in the determination of the efficacy of the activity in cellular lines and in the determination of the anti-angiogenic and anti-metastic in in vivo animals’ models.

Contract number:: RTC-2015-3318-1Total Budget: 573.680,20 € Funding: 534.932,82 €Budget Leitat: 144.994,20€

MICROALMABS ASSESSMENT OF A NEW PLATFORM OF PRODUCTION OF THERAPEUTIC ANTIBODIES

The goal of the project MICROALMABS is the assessment of a system of monoclonal antibodies expression (AcM) in micro algaes. The monoclonal antibodies are essential in the health sector because they are part of the fight against cancer and autoimmune illnesses, both in the diagnoses and therapy. The elevate costs and the Health hazards of the current production methods make necessary the development of expression systems and appropriate methodologies to face the costs and the demands. The micro algaes are exceptional candidates to meet this challenge, especially because of cost reduction and facility of production besides providing more therapeutic and biologic security. Contract number:: RTC-2015-3775-1Total Budget: 520.682,44 € Funding: 469.546 €Budget Leitat: 212.000 €

BATCureDEVELOPING NEW THERAPIES FOR BATTEN DISEASE

The goal of BATCure is to advance the development of new therapeutic options for a group of rare lysosomal diseases – neuronal ceroid lipofuscinoses (NCL) or Batten disease. The project will follow a novel integrated strategy to identify specific gene and small molecule treatments for three genetic types of Batten disease that include the most prevalent world-wide, juvenile CLN3 disease, and in southern and Mediterranean Europe, CLN6 and CLN7 diseases.

The consortium of BATcure consists of 13 members from 7 different countries, mainly universities and research institutes.

http://www.batcure.euGrant Agreement: 666918Total Budget: 5.995.769 € EC Contribution: 5.995.769 €Budget Leitat: 213.962,50 €

GLAMGLASS LASER MULTIPLEXED BIOSENSOR

GLAM will develop an integrated device based on novel label-free photonic biosensors with ultra-sensitivity, simplicity of use, portability, multiplexing and low cost. GLAM capitalizes on the unprecedented sensitivity achieved using laser microring resonators to detect key biomarkers in tumor development and treatment. Point of Care of the device will be carried out by preclinical and clinical sample analysis of genitourinary cancer patients to warrant personalized medicine. The GLAM unique technology will make the device also usable with other biofluids and might also be used to help physicians with other biomarker driven.

The consortium of this project consists of 10 members including industrial companies and research organizations.

http://glam-project.eu/Grant Agreement: 634928Total Budget: 4.835.586 € EC Contribution: 4.835.586 €Budget Leitat: 692.633 €

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ECO-COMPASSECOLOGICAL AND MULTIFUNCTIONAL COMPOSITES FOR APPLICATION IN AIRCRAFT INTERIOR AND SECONDARY

The project ECO-COMPASS aims to bundle the knowledge of research in China and Europe to develop ecological improved composites for the use in aircraft secondary structures and interior. Therefore bio-based reinforcements, resins and sandwich cores will be developed and optimized for their application in aviation. Furthermore the use of recycled man-made fibres to increase the mechanical strength and multifunctional aspects of biocomposites will be evaluated. To withstand the special stress in aviation environment, protection technologies to mitigate the risks of fire, lightning and moisture uptake will be investigated.

Eight European partners and thirteen Chinese partners participate in this project.

Grant Agreement: 690638Total Budget: 4.044.736,25 € EC Contribution: 1.893.685 € Budget Leitat: 340.063 €

RESET RE-USE OF THERMOPLASTICS

RESET project aims to bring a second life to those thermoplastic composites which have been condemned to landfills, to the carbon fibre recovery by means of polymer pyrolysis or to energetic recovery. This milestone will be achieved through a sorting and milling process of these materials, leading to short chopped fibre reinforced thermoplastic granulates. These conditioned leftovers will be subsequently used to obtain new reinforced thermoplastic composites, by melt compounding along with virgin polymer, considering both monocomponent as well as binary blends.

Grant Agreement: 686636Total Budget: 349.156 € EC Contribution: 325.006 €Budget Leitat: 268.656 €

IBDINTENSIFIED BY DESIGN FOR THE INTENSIFICATION OF PROCESSES INVOLVING SOLIDS HANDLING

IbD® will create a holistic platform for facilitating process intensification in processes in which solids are an intrinsic part, the cornerstone of which will be an intensified-by-design® (IbD). The IbD approach is hinged on the use of robust data about a process to ‘redesign’, modify, adapt and alter that process in a continuous, intensified system, and will be the new paradigm in the intensification of processes based on statistical, analytical and risk management methodologies in the design, development and processing of high quality safe and tailored chemicals, pharmaceuticals, minerals, ceramics, etc. under intensified processes.

Twenty-one partners from eight countries participate in this project in collaboration between industrial companies and universities.

http://ibd-project.eu/Grant Agreement: 680565Total Budget: 9.451.056 € EC Contribution: 8.484.493 €Budget Leitat: 337.000 €

MIDWOR-LIFE MITIGATION OF ENVIRONMENTAL IMPACT CAUSED BY DWOR TEXTILE FINISHING CHEMICALS STUDYING THEIR NON-TOXIC

The main objective of the project is to mitigate the environmental, health and safety impacts of current and future Durable Water and Oil Repellents (DWOR) alternatives by analyzing their environmental impact and technical performances in order to assess manufacturers on the best available technologies for repellent finishing. Moreover, the risks of the DWOR alternatives will be evaluated for human and environmental health in the textile finishing industry. In this perspective, policy recommendations will be set in order to promote the widespread implementation of the less toxic and most effective DWOR alternatives to fulfill REACH Regulation.

This project consists of 5 textile companies, 3 of which are Spanish.

http://www.midwor-life.eu/Total Budget: 931.850 € EC Contribution: 554.608 €Budget Leitat: 246.544 €Grant Agreement: LIFE14 ENV/ES/000670

REGROUNDCOLLOIDAL IRON OXIDE NANOPARTICLES FOR THE RECLAMATION OF TOXIC METAL CONTAMINATED GROUNDWATER AQUIFERS, DRINKING WATER WELLS, AND RIVER BANK FILTRATIONS

The main objective of the presented innovation action is the first application and near-market replication of a novel water nanogeotechnology for the immobilization of toxic metals in groundwater aquifers, drinking water wells, and river bank filtration sites. The basic concept of our technology is the creation of an adsorptive in situ barrier for the immobilization of toxic metal contaminations. This barrier is made of iron oxide nanoparticles, which are injected into sediments as colloidal suspension, forming stable deposits there. Over the last 6 years, we have developed

a novel technology for the injection of iron oxide nanoparticles (NPs) into groundwater contaminant plumes. The feasibility of this approach has been successfully tested in lab experiments and a scientific field application.

This project consists of 7 universities and technology centers.

http://reground-project.eu/Grant Agreement: 641768Total Budget: 2.748.750 € EC Contribution: 2.748.750 €Budget Leitat: 160.000 €

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NANOFASENANOMATERIAL FATE AND SPECIATION IN THE ENVIRONMENT

NanoFASE will deliver an integrated Exposure Assessment Framework, including methods, parameter values, model and guidance that will allow Industry to assess the full diversity of industrial nano-enabled products to a standard acceptable in regulatory registrations. Methods to assess how use phases, waste streams and environmental compartments (air, soil, water biota) act as “reactors” in modifying and transporting ENMs will be developed and used to derive parameter values. Our nanospecific models will be integrated with the existing multi-media fate model SimpleBox4Nano for use in EUSES and also develop into a flexible multi-media model for risk assessment at different scales and complexities.

This big consortium consists of 33 members mising industrial companies and research institutes.

http://nanofase.eu/Grant Agreement: 646002 Total Budget: 11.296.705 € EC Contribution: 9.954.479 € Budget Leitat: 519.451 €

RICAS2020DESIGN STUDY FOR THE EUROPEAN UNDERGROUND RESEARCH INFRA-STRUCTURE RELATED TO ADVANCED ADIABATIC COMPRESSED AIR ENERGY STORAGE

RICAS2020 will provide an innovative design concept of an Underground Research Infrastructure to develop technologies by which the storage of very high amounts of “green” energy will be possible. The big advantage of the new design concept will be the independence from the encountered geological conditions. This means that energy will be directly stored at all places where high energy demands will exist.

The consortium consists of 6 partners, mainly Swiss industrial companies.

http://www.ricas2020.eu/Grant Agreement: 654387Total Budget: 1.373.638 € EC Contribution: 1.373.638 € Budget Leitat: 90.000 €

ALION HIGH SPECIFIC ENERGY ALUMINIUM-ION RECHARGEABLE BATTERIES FOR DECENTRALISED ELECTRICITY GENERATION SOURCES

The overall objective of the ALION project is to develop aluminium-ion battery technology for energy storage application in decentralised electricity generation sources. ALION pursues an integral approach comprising electroactive materials based on “rocking chair” mechanism, robust ionic liquid-based electrolytes as well as novel cell and battery concepts, finally resulting in a technology with much lower cost, improved performance, safety and reliability with respect to current energy storage solutions.

This project consists of 13 partners, mainly industrial companies, from 6 European countries.

http://www.alionproject.eu/Grant Agreement: 646286Total Budget: 7.223.551,25 € EC Contribution: 7.223.551,25 € Budget Leitat: 565.965 €

ALISEADVANCED LITHIUM SULPHUR BATTERY FOR HYBRID ELECTRIC VEHICLE

ALISE is a pan-European collaboration focused on the development and commercial scale-up of new materials and on the understanding of the electrochemical processes involved in the lithium sulphur technology. It aims to create impact by developing innovative battery technology capable of fulfilling the expected and characteristics from European Automotive Industry needs, European Materials Roadmap, Social factors from vehicle consumers and future competitiveness trends and European Companies positioning. The project is focused to achieve 500 Wh/Kg stable LiS cell.

The consortium of ALISE consists of 15 partners, mainly industrial associations, from 5 European countries.

http://aliseproject.com/Grant Agreement: 666157Total Budget: 6.899.233 € EC Contribution: 6.899.233 € Budget Leitat: 694.819 €

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31

VENAIRMrs. Norma Ferrer R&D Manager

Venair is an international business group, with presence in 65 countries, technology leader in engineering and manufacture of silicon tubes for the most demanding sectors such as pharmaceutical, biotechnological or aeronautics.

The company is pioneer in Europe in the manufacturing of high performance silicon and offers specific engineering solutions to each client thanks to the development of high purity silicon tubes in a short space of time. The products of Venair have also application in chemical processes, cosmetic sector and alimentary and industrial uses, among others. Venair considers crucial innovation and development, so that it is vital to collaborate with a technological center as Leitat to keep on innovating and growing. Venair and Leitat started collaboration in 2014 with a concrete project and from then on the collaboration opportunities have been growing and will keep on growing for a long time.

NIFCO Mr. Albert Serarols Quality Department

Nifco Products España S.L. is a company entirely dedicated to the manufacture of thermoplastic pieces and assembly of sets for the automotive sector. It is part of the Nifco Inc. group, with worldwide presence and leadership in the manufacture of plastic pieces for the automotive sectors, “Home electric appliances” as well as sportive products. With about 50 years experience in the market, the goal of the group is the manufacture of pieces based on the highest quality standards contributing to reduce weight and environmentally friendly.

Our collaboration with Leitat started more than 12 years ago. Its staff and its technology solvency have always been a great support to offer high quality products to our customers. Therefore, we have initiated an internationalization process and nowadays our market share multiplied in several occasions.

In the last years, Nifco Products España S.L. has experimented strong growth, which has in turn strengthen the existing professional link with Leitat, due to the most demanding levels of the current market. That is why we keep on trusting on Leitat as technology partner to keep on supporting and helping us to reach our current and future goals.

BIOSYSTEMSMr. Petraki Munujos, PhDR&D Projects Director

BioSystems is a company with subsidaries globally distributed and belonging to the Ginper Group, that since 1981 it focus its activity on R+D to develop, produce and commercialize instruments and reliable reagents for analysis, specially aimed at clinical diagnoses and agro-alimentary sector. The goal of BioSystems is contributing to improve health of people, by providing equipment and reagents of high quality performance, as a result of the continuous improvement process and adaptation to the users.

As a result of the process based on R+D of excellence of its products, some years ago BioSystems opted for establishing close collaboration with Leitat in the design and development of new products, since it is an innovation benchmark in our country. Nowadays, Biosystems has different open projects with Leitat, both with the Biomed Division and the Industrial Design and Development Division, among which there is the the project founded by CDTI (Research and Development Projects – RDP) for the development of a new turbidimetric reagent (2015-2016). Due to the technical complexity of the products intended to be developed and the distance with the current business activity of BioSystems, Leitat has provided strong scientific and technical support, highly professional and external key advising on the design and implementation of new products. Furthermore, the collaboration with Leitat has always been close in order to meet the needs of BioSystems, with high willingness to interchange ideas for a better use of the resources and improvement of the productive processes.

The collaboration with Leitat is providing technical and competitive advantages and an innovative vision that Biosystems expects to keep on enjoying for a long time. To do so, new collaboration agreements are intended to be initiated for the design of more innovative products and therefore strengthen the global recognition of BioSystems in the clinical diagnoses sector.

COUNCIL OF VILANOVA DEL CAMÍ

In 2014, the Innovation Center of l’Anoia in Vilanova del Camí was inaugurated. A center led by the Council of Vilanova del Camí, with the complicity and the commitment of more than twenty local entities and economic and social agents of the zone, with the aim of giving value to innovation and technology research of the town and the region.

The project involves the service delivery of added value: training, gathering spaces, resources for companies and mechanisms to promote innovation and cooperation among entrepreneurs favoring the competitiveness of the region.

With the will of innovating, improving competitiveness of the zone and being a benchmark in the research field, the Council of Vilanova del Camí looked for a strong partner to share these aims and work in the same line. Leitat, thanks to its track record and European relevance, is an excellent partner with which the Council is working closely in the Innovation Center of l’Anoia, making it known and making advantage of the synergies offered by this center to promote technology research and innovation to the region.

OUR CUSTOMERS’ OPINION

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GERMANS BOADA S.A. Mr. Xavier DalmauTechnical Manager

Germans Boada is a company dedicated to the manufacturing and commercialization of machinery, both manual and electrical, to cut ceramics, although nowadays it offers a wide range of additional products aimed at the building sector. Today, the group is present in more than 100 countries and it is leader in the markets of Spain, Portugal, France and the United Kingdom, besides the annual strong growth in North America and Near Est. The typology of our products, many of them with a limited technology load, besides the strong Asian competition, makes an extra effort and innovation necessary in order to keep on leading our markets and open to new ones.

We contacted with Leitat for the first time 11 years ago, when Leitat was still in its former headquarters in Terrassa. The first tasks requested were certification of PPE. Then, the collaboration strengthened, and besides it keeps on being a reliable partner for testing and calibrations, Leitat gave us support in R+D projects that helped to increase the added value of our products.

During all these years of collaboration with Leitat, we treated with different persons within the organization, reaching high commit-ment level, professionalism and customer service. Analyzing our experience with Leitat up to now, from Germans Boada we can only predict greater collaboration in the near future.

NAD, S.L. Mollet del Vallès

In the last years, thanks to the performance of new Projects OEM by prestigious international brands and the expansion of the mark SHAD into the international markets, the activity of NAD, S.L. has experienced great growth concerning models and markets. The requirements of our customers and distributors concerning homologations and quality control are more demanding each time. In this scene, Leitat offers us an almost 100% coverage of the tests necessary for these processes. In the few cases in which Leitat was not able to perform the necessary tests, the willingness by Leitat to the research of an alternative solution that has enabled us to find always the solution to work with.

As services supplier, Leitat characterizes by its fast answer to our demands, the value that the experience and knowledge of its staff provide to the process and the proactive communication and feedback with customers.

OUR CUSTOMERS’ OPINION

2015 ACTIVITY REPORT

Photo_Corporate_Headquarters_Source_Archives_Leitat

45%Men(105)

2015 ACTIVITY REPORT

STAFF

Leitat Technological Center has opted for an increase in the number of employees, which currently consists of a team of specialists in different areas of knowledge, and investment in talent management policy to offer high added value technology response.

194214 225

Number of collaborators (average)

54%College Graduates(126)

26%Doctors

(60)

55%Women(127)

OUTPUTS 2015

65 R&D +2i ongoing European projects*

90 R&D +2i ongoing National projects

29 Projects led

267 Industrial projects

3.305 Advanced Technology Solutions

*We are participating in European projects with a total of 538 partners, overall budget of 407M €, and collaborating with 34 countries

34

Distribution 2015 Average age 35 years

232

· Number of collaborators (average)

College Graduates 2015

· Distribution 2015 – Average age 35 years

20%Others: (46)

232

2015 ACTIVITY REPORT

INCOME:

In recent years, the evolution of Leitat has been focused on creating sustainable and lasting value technology, aligned with the needs and expectations of the market, with an economic return for companies and institutions.

Fixed assets: 14.549

Debtors: 12.919

Financial assets: 4.761

Total 32.229

Shareholders’ equity: 9.849

Non-current assets: 10.021

Current assets: 12.359

Total 32.229

BALANCE 2015thousand Euros

Distribution of total revenues by activity*STA, Advanced Technology Solutions

Income distribution by type of R&D+2i project

90%R+D Projects 10%

*STA

35

16,5

Projects with non competitiveness public fundingOwn and Company R+D+I projects

70%R+D+I projects forcompanies

30%Own

R+D+I projects

EBITDA (Euros)

2.01

6.17

5

1.69

3.99

9

1.79

5.49

8

1.78

4.26

6

1.49

6.58

3

15,817,9 17,1 18

13,914,9 14,7 15,3 16,5

Income in thousand Euros

With society

Decisive commitment for dual training as basic tool of the business fabric and the educative community for the creation of new professional profiles linked to the industrial sector and R+D. Leitat does not only actively and jointly participate in the creation of these new professional profiles but it also participates in workshops. Collaboration in mentoring programs to insert young people into the labor market, through the collaboration with Barcelona Activa.Collaboration with non-profit foundations for the promotion of campaigns and collaborations of corporate volunteering.

• Collaboration with awards to young enterprisers as evaluation part in the institutional and technical jury.

• Promotion and diffusion of scientific studies among students, who are the knowledge and innovation future workers by collaborating with public and private entities in specific projects.

• Series of conferences and welcome programs for internship students working in the different research and technology solution areas in Leitat, both at national level and with international associtations, by hosting students with Leonardo grants, Erasmus programs, etc.

• Collaboration with the local agents (Consortium for the Occupation of Vallès Occidental) in strategic policies linked to the entrepreneurship and environmental sustainability and the attraction of business economic activity generating direct impact on the creation of job offers linked to industry.

• Participation in the “Week of the Science”, by offering our facilities to visits specialised in the future technology thematic and lines.

• Conference on Professional and Business Orientation aimed at Institutes, private schools and universities.

• Participation in working groups with the different public representatives, in the formulation of possible proposals that develop into executive actions and legal measures that facilitate positive impact on the reactivation and economic growth mainly based on Research, Development and Innovation (R+D+i), and in particular on the real transfer of knowledge towards the SME business fabric. .

With our employees

• Investment in training plans according to the needs of our employees, their performance and career, applying an annual estimate depending on the needs of each organization department of Leitat.

• Subsidy and promotion of doctoral degrees.• Offering our employees the chance to give and receive inner/external training.• Promotion and development of our employees in the following and management

of students in internship.• Welcome actions to facilitate the adaptation of internship students of different

cultures for their integration in Leitat.• Reinforcement of the corporative culture through different channels to facilitate

inner communication.• Realization of after-work activities to encourage a satisfactory and conciliatory

atmosphere among the staff.• Specific campaigns on the promotion of healthy habits in the daily life, environment,

risk prevention and security for all.• Existence of the Agent for Equality in the welcome programs and training actions

aimed at our personnel.• Reconciliation measures and flexibility for our staff.

OUR COMMITMENT 2015We keep on strengthen our commitment with the Corporate Social Responsibility through initiatives aimed at providing social and technology value to our stakeholders: clients, partners, associated, people and society.

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Organismo notificado 0162

SOCIAL NET:

TerrassaVilanova del camí

2016 Corporate Report

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