23472397 abdominal trauma

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    Abdominal TraumaAbdominal Trauma

    Dr. Qiu XinguangDr. Qiu Xinguang

    Department ofDepartment of General Surgery,General Surgery,

    First Affiliated Hospital, Zhengzhou UniversityFirst Affiliated Hospital, Zhengzhou University(450052)(450052)

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    Mechanism of InjuryMechanism of Injury

    Blunt injuryBlunt injury

    Penetrating injuryPenetrating injury

    Blast injuryBlast injury Iatrogenic injuryIatrogenic injury

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    Blunt injuryBlunt injury

    Commonest modeCommonest mode

    Frequently multiFrequently multi--system injurysystem injury

    Abdominal injury accounts for 10%Abdominal injury accounts for 10%blunt trauma deathblunt trauma death

    Road traffic accidentRoad traffic accident

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    Mechanism of blunt injuryMechanism of blunt injury

    Direct impactDirect impact

    Deceleration and rotational forcesDeceleration and rotational forces

    Liver and spleen are the mostLiver and spleen are the mostcommonly injured organscommonly injured organs

    Bowel injury (acute increase inBowel injury (acute increase in

    intraluminal pressure / shearing atintraluminal pressure / shearing atmesentery)mesentery)

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    Penetrating injuryPenetrating injury

    High velocityHigh velocity

    Gunshot woundsGunshot wounds

    Low velocityLow velocity

    Stab wounds / lowStab wounds / low--velocity missilesvelocity missiles

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    Mechanism of penetrating injuryMechanism of penetrating injury

    Stab woundsStab wounds

    Injury confined to the tract ofInjury confined to the tract ofwoundingwounding

    Gunshot woundsGunshot wounds

    Depends on the energy transferredDepends on the energy transferred

    Penetration is accompanied by shockPenetration is accompanied by shockwave with cavitating effect (spiralwave with cavitating effect (spiralpath of motion)path of motion)

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    Iatrogenic injuryIatrogenic injury

    UncommonUncommon

    LaparoscopyLaparoscopy

    EndoscopyEndoscopy

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    Primary survey and resuscitationPrimary survey and resuscitation

    Objectives of this phase:Objectives of this phase:To identify and correct any immediate lifeTo identify and correct any immediate life--threatening conditionsthreatening conditionsTo anticipate problemsTo anticipate problems

    The activities are performed simultaneously withThe activities are performed simultaneously withenough personnelenough personnelAA-- Airway and cervical spine controlAirway and cervical spine controlBB-- BreathingBreathingCC-- Circulation with haemorrhage controlCirculation with haemorrhage controlDD-- DisabilityDisabilityEE-- ExposureExposure

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    Airway and CAirway and C--spinecontrolspinecontrol

    CC--spine injury should be assumedspine injury should be assumed

    No attempt should be made to turnNo attempt should be made to turn

    the patientthe patients head to one side unlesss head to one side unlessCC--spine injury has been ruled outspine injury has been ruled out

    Oxygen provided once airway clearedOxygen provided once airway clearedand securedand secured

    Beware of aspirationBeware of aspiration

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    BreathingBreathing

    Anticipate SIX immediately lifeAnticipate SIX immediately life--threateningthreateningthoracic conditions:thoracic conditions:1. Airway obstruction1. Airway obstruction2. Tension pneumothorax2. Tension pneumothorax

    3. Open chest wound3. Open chest wound4. Massive haemothorax4. Massive haemothorax5. Flail chest5. Flail chest6. Cardiac tamponade6. Cardiac tamponade

    Respiratory rate and effort are both sensitiveRespiratory rate and effort are both sensitivemarkers of underlying lung pathology (bothmarkers of underlying lung pathology (bothshould be monitored)should be monitored)

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    CirculationCirculation

    Key objectives of circulatory care:Key objectives of circulatory care:

    Stop haemorrhageStop haemorrhageAssess hypovolaemiaAssess hypovolaemia

    Vascular assessVascular assess

    Appropriate fluid resuscitationAppropriate fluid resuscitation

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    Stop haemorrhageStop haemorrhage

    Direct pressure (external haemorrhage)Direct pressure (external haemorrhage)

    Long bone fractures be splintedLong bone fractures be splinted

    Pelvic bindingPelvic binding

    Pneumatic antiPneumatic anti--shock garment (PASG)shock garment (PASG)

    Pelvic fracture may need external fixationPelvic fracture may need external fixation

    Try to avoid:Try to avoid:

    Vessel clampingVessel clamping

    Tourniquets (distal ischaemia)Tourniquets (distal ischaemia)

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    Assessment forhypovolaemiaAssessment forhypovolaemia

    Skin (colour, clamminess and capillary refill)Skin (colour, clamminess and capillary refill)

    Heart rate and BPHeart rate and BP

    Pulse pressurePulse pressure

    Conscious levelConscious level ECG monitoringECG monitoring

    Search for common sites of occult bleeding:Search for common sites of occult bleeding:

    ChestChest

    Abdomen / RetroperitoneumAbdomen / Retroperitoneum

    PelvisPelvis

    Long bonesLong bones

    Splints and dressingsSplints and dressings

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    VascularassessVascularassess

    Large bore IV catheterLarge bore IV catheter

    20ml blood taken for grouping and x20ml blood taken for grouping and x--

    match and for ematch and for e--

    + full blood count+ full blood count Femoral line / venous cut down /Femoral line / venous cut down /

    intraintra--osseous access (if peripheral IVosseous access (if peripheral IVassess failed)assess failed)

    Central venous line insertion is notCentral venous line insertion is notessential for initial resuscitationessential for initial resuscitation

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    Fluid resuscitationFluid resuscitation

    Initial fluid resuscitation:Initial fluid resuscitation:

    2L warmed crystalloid2L warmed crystalloid

    Responder: Give maintenance fluids onceResponder: Give maintenance fluids once

    initial deficit replacedinitial deficit replaced Transient responder: Deteriorate due toTransient responder: Deteriorate due to

    continued haemorrhage, give blood andcontinued haemorrhage, give blood andurgent surgical opinionurgent surgical opinion

    NonNon--responder: Ongoing haemorrhage atresponder: Ongoing haemorrhage ata greater rate, need urgent surgicala greater rate, need urgent surgicalopinionopinion

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    Resuscitation endResuscitation end--pointpoint

    Administer sufficient fluids to maintain perfusionAdminister sufficient fluids to maintain perfusionof essential organsof essential organs

    SBP 80mmHg (previously normotensive)SBP 80mmHg (previously normotensive) Equivalent to a palpable radial pulseEquivalent to a palpable radial pulse Permissive hypotension to minimizePermissive hypotension to minimize

    Ongoing haemorrhageOngoing haemorrhageDisruption of established thrombusDisruption of established thrombusDilution of clotting factorsDilution of clotting factors

    Monitored vitals:Monitored vitals:Resp rate, SaO2, HR, BP, Pulse pressure, CardiacResp rate, SaO2, HR, BP, Pulse pressure, Cardiacmonitoring, Temp, Urine output, GCSmonitoring, Temp, Urine output, GCS

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    Urethral injuryUrethral injury

    Far more common in male patientsFar more common in male patients

    55--25% patients with pelvic fractures have an25% patients with pelvic fractures have anassociated urethral injuryassociated urethral injury

    Symptoms:Symptoms:

    Perineal painPerineal pain

    DysuriaDysuria

    Failure to voidFailure to void

    Signs:Signs:

    Blood at urethral meatusBlood at urethral meatus

    Bruising around scrotumBruising around scrotum

    HighHigh--riding prostateriding prostate

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    Urethral injuryUrethral injury

    Urinary catheterization isUrinary catheterization iscontraindicated:contraindicated:

    Conversion of partial to completeConversion of partial to completetransectiontransection

    Stricture formationStricture formation

    Introduce infectionIntroduce infection Diagnosis confirmed by retrogradeDiagnosis confirmed by retrograde

    urethrogramurethrogram

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    DisabilityDisability

    Baseline neurological examination:Baseline neurological examination:

    AVPU responseAVPU response

    Glasgow comma scale (if time permits)Glasgow comma scale (if time permits)

    Pupillary responsePupillary response Repeated assessment to look for signs ofRepeated assessment to look for signs of

    deteriorationdeterioration

    Common causes of deterioration:Common causes of deterioration:

    HypoxiaHypoxia

    HypovolaemiaHypovolaemia

    HypoglycaemiaHypoglycaemia

    Raised ICPRaised ICP

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    ExposureExposure

    Trauma victims must be kept warmTrauma victims must be kept warmand covered with blankets when notand covered with blankets when notexaminedexamined

    LogLog--rollroll

    Assess the spine from skull base toAssess the spine from skull base tococcyxcoccyx

    Examine the back for signs of injuryExamine the back for signs of injury

    Rectal examinationRectal examination

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    Secondary surveySecondary survey

    (abdominal examination)(abdominal examination)

    Key objective:Key objective:

    To decide if laparotomy is neededTo decide if laparotomy is needed

    Detailed examination of the abdomen,Detailed examination of the abdomen,

    pelvis and perineumpelvis and perineum Note for bruising and woundsNote for bruising and wounds

    Cover exposed bowel loops with warm NSCover exposed bowel loops with warm NSsoaked gauzesoaked gauze

    Gastric tube to decompress distendedGastric tube to decompress distendedstomach to facilitate abdominalstomach to facilitate abdominalexamination and reduce risk of aspirationexamination and reduce risk of aspiration

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    Physical examinationPhysical examination

    Most alert patients will haveMost alert patients will have abdominalabdominaltendernesstenderness

    Initial PE in blunt abdominal trauma isInitial PE in blunt abdominal trauma is

    only 65% accurateonly 65% accurateAltered mental state (drugs, alcohol, HI,Altered mental state (drugs, alcohol, HI,etc)etc)

    Sensory abnormalities (spinal cord injury)Sensory abnormalities (spinal cord injury)

    Distracting injuries (extraDistracting injuries (extra--abdominal)abdominal) Serial examinations are often moreSerial examinations are often more

    importantimportant

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    Physical findingsPhysical findings

    DistensionDistension

    Usually 2Usually 200 to ileus orto ileus or

    pneumoperitoneum orpneumoperitoneum orhaemoperitoneumhaemoperitoneum

    BruisingBruising

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    PalpationPalpation

    Lower ribs fractureLower ribs fracture

    Abdominal tenderness, guarding orAbdominal tenderness, guarding orreboundrebound

    Pelvic stabilityPelvic stability Lumbar spine for tendernessLumbar spine for tenderness

    Rectal examinationRectal examination

    Anal toneAnal tone

    Prostate position (?high riding)Prostate position (?high riding)

    Blood over examination gloveBlood over examination glove

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    Plain radiographsPlain radiographs

    CXRCXR

    The most important plain filmThe most important plain film

    Obvious intraObvious intra--thoracic andthoracic anddiaphragmatic injuriesdiaphragmatic injuries

    Pelvis (AP view)Pelvis (AP view)

    CC--spine (Lat view) make sure Cspine (Lat view) make sure C11--CC77are well shownare well shown

    AXR seldom helpful (not routine)AXR seldom helpful (not routine)

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    Laboratory studiesLaboratory studies

    Laboratory tests play limited role inLaboratory tests play limited role inthe diagnosis of IAI (normal testthe diagnosis of IAI (normal testnever R/O IAI)never R/O IAI)

    Baseline Hb levelBaseline Hb level

    AcidAcid--base statusbase status

    Amylase (not sensitive / specific)Amylase (not sensitive / specific) Urinalysis (gross haematuria is theUrinalysis (gross haematuria is the

    most consistent sign of serious renalmost consistent sign of serious renalinjury)injury)

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    Diagnostic peritoneal lavageDiagnostic peritoneal lavage

    Before the introduction of DPL ~20%Before the introduction of DPL ~20%patient with abdominal trauma died ofpatient with abdominal trauma died ofunrecognized injuryunrecognized injury

    Sensitive 97Sensitive 97--99%99% Fast (5Fast (5--15 min)15 min) False +ve 1.4%False +ve 1.4% Complication rate 1%Complication rate 1% No information on retroperitoneal organsNo information on retroperitoneal organs Not sensitive to detect diaphragmatic orNot sensitive to detect diaphragmatic or

    bladder injuries (these result in minimalbladder injuries (these result in minimalbleeding)bleeding)

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    Contraindication ofPDLContraindication ofPDL

    AbsoluteAbsolute

    Obvious need for laparotomyObvious need for laparotomy

    EviscerationEvisceration RelativeRelative

    Pregnancy (>12 wks)Pregnancy (>12 wks)

    Previous abdominal surgeryPrevious abdominal surgery

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    Criticism ofPDLCriticism ofPDL

    Overly sensitiveOverly sensitive

    NonNon--bleeding solid organ injuriesbleeding solid organ injuries

    (which can be managed(which can be managedconservatively)conservatively)

    NonNon--therapeutic laparotomiestherapeutic laparotomies

    Best preserved for hypotensive,

    Best preserved for hypotensive,unstable, multiunstable, multi--injured patientsinjured patients

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    TechniquesTechniques

    Closed percutaneousClosed percutaneous

    SemiSemi--closedclosed

    OpenOpen

    1 Liter1 Liter of warmof warm normal salinenormal saline is instilledis instilledin adultsin adults

    15 ml/kg in children15 ml/kg in childrenA minimum ofA minimum of300 ml300 ml of lavage fluid mustof lavage fluid mustreturn to give a representative samplereturn to give a representative sample

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    Positive results ofDPLPositive results ofDPL

    10ml gross blood or bowel contents10ml gross blood or bowel contentswith initial aspirationwith initial aspiration

    RBC count >100,000 cells/ml inRBC count >100,000 cells/ml inblunt traumablunt trauma

    RBC count >10,000 cells/ml in stabRBC count >10,000 cells/ml in stabwoundswounds

    RBC count >5000 cells/ml inRBC count >5000 cells/ml inpenetrating chest traumapenetrating chest trauma

    WBC count >500 cells/mlWBC count >500 cells/ml

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    UltrasoundUltrasound

    Kristensen et al first reported the use ofKristensen et al first reported the use ofUSG in abdominal trauma in 1971USG in abdominal trauma in 1971

    NonNon--invasive and inexpensiveinvasive and inexpensive

    Portable (bed side)Portable (bed side) No radiation / contrast requiredNo radiation / contrast required Well tolerated (excellent for unstableWell tolerated (excellent for unstable

    patients)patients) Quick (within 3 mins in experienced hands)Quick (within 3 mins in experienced hands) Serial examination easy to performSerial examination easy to perform Best screens for haemoperitoneumBest screens for haemoperitoneum

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    FAST techniqueFAST technique

    Focused Abdomianl Sonography forFocused Abdomianl Sonography forTrauma (Rozycki et al)Trauma (Rozycki et al)

    A standard approach which involvesA standard approach which involves

    imaging a limited number of US windowsimaging a limited number of US windowsto detect fluid:to detect fluid:

    RUQ (MorisonRUQ (Morisons pouch)s pouch)

    LUQ (to view the spleen)LUQ (to view the spleen)

    Pelvis (Douglas pouch)Pelvis (Douglas pouch)Pericardial window to assess forPericardial window to assess forpericardial effusion (epigastric)pericardial effusion (epigastric)

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    Reliability ofFASTReliability ofFAST

    Sensitivity 93.4%Sensitivity 93.4%

    Specificity 98.7%Specificity 98.7%

    Accuracy 97.5%Accuracy 97.5%A collected review of ~5000 patientsA collected review of ~5000 patients(with FAST performed by surgeons)(with FAST performed by surgeons)

    Rozycki and Shackford J Trauma 1996; 28: 483Rozycki and Shackford J Trauma 1996; 28: 483--99

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    Results interpretationResults interpretation

    Unstable patients with a +ve USUnstable patients with a +ve USrequires laparotomyrequires laparotomy

    Stable patients can be followed byStable patients can be followed byserial US or employ CT for furtherserial US or employ CT for furtherevaluationevaluation

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    LimitationsLimitations

    Operator dependentOperator dependent

    Uncooperative / agitated patientsUncooperative / agitated patients

    ObesityObesity

    Surgical emphysemaSurgical emphysema

    IleusIleus

    Cannot assess retroperitoneal organsCannot assess retroperitoneal organs

    Like CT, US is insensitive for bowel injuryLike CT, US is insensitive for bowel injury

    Poor sensitivity for penetrating traumaPoor sensitivity for penetrating trauma

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    Abdominal computed tomographyAbdominal computed tomography

    Introduced in late 1970s for traumaIntroduced in late 1970s for traumamanagementmanagement

    CT quantifies intraperitoneal bloodCT quantifies intraperitoneal blood

    and grades organ injuryand grades organ injury IV and oral contrastIV and oral contrast

    Accuracy is extremely readerAccuracy is extremely reader--

    dependentdependent Modern spiral scan requires 3Modern spiral scan requires 3--5 mins5 mins

    Dome of diaphragm to pelvisDome of diaphragm to pelvis

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    PrecautionsPrecautions

    Haemodynamically stableHaemodynamically stable

    More time consuming than DPL /More time consuming than DPL /

    FASTFAST 3030--50 min50 min

    Adequate monitoringAdequate monitoring

    Resuscitation facilities must beResuscitation facilities must beavailable in the CT roomavailable in the CT room

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    Diagnostic laparoscopyDiagnostic laparoscopy

    DL is a relatively new investigationDL is a relatively new investigation Little evidence to support its role in bluntLittle evidence to support its role in blunt

    traumatrauma

    Not sensitive in Dx hollow viscus andNot sensitive in Dx hollow viscus andretroperitoneal injuryretroperitoneal injury Penetrating trauma (stab wounds) inPenetrating trauma (stab wounds) in

    stable patientstable patient100% sensitivity100% sensitivity for identification offor identification of

    peritoneal penetrationperitoneal penetration Most effective for diagnosing rupturedMost effective for diagnosing ruptured

    diaphragmdiaphragm

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    Limitation ofDLLimitation ofDL

    Time consumingTime consuming

    InvasiveInvasive

    General anaestheticGeneral anaesthetic Difficult to exclude hollow viscusDifficult to exclude hollow viscus

    perforationperforation

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    Management approach forManagement approach for

    blunt abdominal traumablunt abdominal trauma Unstable patient with abdominal signUnstable patient with abdominal sign

    OperationOperation

    Unstable patient with uncertain abdominal injuryUnstable patient with uncertain abdominal injury

    DPL or FASTDPL or FAST Stable patient with associated severe injuriesStable patient with associated severe injuries

    DPL or FASTDPL or FAST

    Stable patient with associated minor injuries andStable patient with associated minor injuries andequivocal abdomenequivocal abdomen

    CT scanCT scan Stable patient with abdominal signsStable patient with abdominal signs

    CT scan (allowing nonCT scan (allowing non--operative Tx if appropriate)operative Tx if appropriate)

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    Stab woundsStab wounds

    Penetrates peritoneum in 2/3 casesPenetrates peritoneum in 2/3 cases Only 50Only 50--70% of these have significant70% of these have significant

    visceral or vascular injuryvisceral or vascular injury

    Selective laparotomies to reduce morbiditySelective laparotomies to reduce morbidityand hospital stay in haemodynamicallyand hospital stay in haemodynamicallystable patientsstable patients

    Diagnostic aids:Diagnostic aids:Wound explorationWound exploration

    DPLDPLLaparoscopyLaparoscopySerial examinationsSerial examinations

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    Lumbarand flank woundsLumbarand flank wounds

    Significantly less risk (

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    Management approach forManagement approach for

    penetrating abdominal traumapenetrating abdominal trauma

    Sensitivity ofCT or US are far too low toSensitivity ofCT or US are far too low toexclude intraexclude intra--abdominal injuryabdominal injury

    Stab woundsStab wounds

    Peritoneal penetrationPeritoneal penetration pp LaparotomyLaparotomyDiagnostic laparoscopyDiagnostic laparoscopy ss LaparotomyLaparotomy

    Wound explorationWound exploration ss LaparotomyLaparotomy

    Gunshot woundsGunshot wounds

    Obligatory laparotomyObligatory laparotomy

    Diagnostic laparoscopyDiagnostic laparoscopy ss LaparotomyLaparotomy

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    Incidence ofIAI requiringIncidence ofIAI requiring

    exploratory laparotomyexploratory laparotomy

    BluntBlunt%%

    PenetratinPenetrating %g %

    SpleenSpleen 4747 77LiverLiver 5151 2828

    Pancreas /Pancreas /

    DuodenumDuodenum

    1010 1111

    ColonColon 55 2323

    Stomach /Stomach /Small bowelSmall bowel

    99 4242

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    Management PrioritizationManagement Prioritization

    Concurrent head injuriesConcurrent head injuries

    An exsanguinating abdominal injuryAn exsanguinating abdominal injury

    demands a laparotomy to controldemands a laparotomy to controlbleeding before assessment of the HIbleeding before assessment of the HI

    Pelvic fracturePelvic fracture

    Rapid application of external fixatorRapid application of external fixatorto stabilize the pelvis beforeto stabilize the pelvis beforelaparotomylaparotomy

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    NonNon--operative management ofoperative management of

    solid organ injurysolid organ injury

    Increasing evidence to support nonIncreasing evidence to support non--operative Mxoperative Mx

    Parallels with the wideParallels with the wide--spread use ofspread use ofCTCT

    Clinical criteria (not CT grading) areClinical criteria (not CT grading) areused for decision makingused for decision making

    Must be continuously monitored inMust be continuously monitored inHDU or ICU settingHDU or ICU setting

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    Criteria for nonCriteria for non--operativeMxoperativeMx

    Solid organ injury shown on CT scanSolid organ injury shown on CT scan

    Minimal abdominal signsMinimal abdominal signs

    Haemodynamically stableHaemodynamically stable Requires

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    Success rate of nonSuccess rate of non--operativeMxoperativeMx

    LiverLiver

    5050--80%80%

    SpleenSpleen93% for minor injuries93% for minor injuries

    RenalRenal

    Majority can be Mx conservativelyMajority can be Mx conservativelyunless there is injury to renal pedicleunless there is injury to renal pedicleor massive damageor massive damage

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    Intervention radiologyIntervention radiology

    AngiographyAngiography ss embolizationembolization

    Both diagnostic and therapeuticBoth diagnostic and therapeutic

    Common useCommon usePelvic fracture with bleedingPelvic fracture with bleedinguncontrolled by fixationuncontrolled by fixation

    Solid organ injurySolid organ injury

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    Damagecontrol surgeryDamagecontrol surgery

    10% trauma patients cannot tolerate10% trauma patients cannot toleratedefinitive procedure at initial laparotomydefinitive procedure at initial laparotomy

    Survival benefit demonstrated with theSurvival benefit demonstrated with the

    use ofuse ofdamage controldamage control approachapproachControl bleedingControl bleeding

    Injured bowel stapled without anastomosisInjured bowel stapled without anastomosis

    Solid organ injury packedSolid organ injury packedAbdomen rapidly closed with towel clips orAbdomen rapidly closed with towel clips orplastic bagplastic bag

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    Indications for damagecontrolIndications for damagecontrol

    HypothermiaHypothermia ee353500CC

    Acidosis pH

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    Abdominal compartment syndromeAbdominal compartment syndrome

    ACS: A group of adverse progressiveACS: A group of adverse progressivephysiological effects of raised intraphysiological effects of raised intra--abdominal pressureabdominal pressure

    Abdominal trauma is the commonestAbdominal trauma is the commonestcausecause

    Pressure required to precipitate ACSPressure required to precipitate ACS

    is unknown (varies with individuals)is unknown (varies with individuals) Most will require decompression atMost will require decompression at

    2525--35 cmH35 cmH22OO

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    Predisposing factors in traumaPredisposing factors in trauma

    patientspatients

    Massive intraMassive intra--abdominal bleedingabdominal bleeding

    Visceral edema (ischaemiaVisceral edema (ischaemia--

    reperfusion)reperfusion) Vigorous fluid resuscitationVigorous fluid resuscitation

    SurgerySurgery

    PackingPacking

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    PathophysiologyPathophysiology

    Diaphragmatic splinting (Resp)Diaphragmatic splinting (Resp)

    Pressure on IVC (Decreases venousPressure on IVC (Decreases venous

    return and thus cardiac output)return and thus cardiac output) Oliguria (Direct renal compressionOliguria (Direct renal compression

    +/+/-- reduced systemic blood flow)reduced systemic blood flow)

    The condition is fatal unless treatedThe condition is fatal unless treatedbefore irreversible physiologicalbefore irreversible physiologicalinsult occursinsult occurs

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    Major systems affectedMajor systems affected

    PulmonaryPulmonary

    CardiovascularCardiovascular

    RenalRenal

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    Treatment ofACSTreatment ofACS

    Urinary manometry to monitor theUrinary manometry to monitor theintraabdominal pressureintraabdominal pressure

    Nasogastric decompressionNasogastric decompression

    Abdominal decompressionAbdominal decompression

    Control of haemorrhageControl of haemorrhage

    Evacuation of gauze packs and bloodEvacuation of gauze packs and blood

    Delayed wound closure (temporaryDelayed wound closure (temporaryplastic wrap)plastic wrap)

    Ventilatory support till definitiveVentilatory support till definitive

    closure (optimally in 2closure (optimally in 2--3 days time)3 days time)

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    Thank you!Thank you!

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    PhD. Qiu XinguangPhD. Qiu Xinguang

    [email protected]@yahoo.com

    03710371--6511 57776511 5777

    1380371071013803710710