2,5-dimethoxyamphetamine
DESCRIPTION
Monografia de SubstânciaTRANSCRIPT
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The Drug Enforcement Administrations Special Testing and Research Laboratorygenerated this monograph using structurally confirmed reference material.
Page 1 of 5SWGDRUG.org/monographs.htmLatest Revision: 12/16/2013
Form Chemical Formula Molecular Weight Melting Point (oC)Base C11H17NO2 195 Not DeterminedHCl C11H17NO2 . HCl 231 108.8HBr C11H17NO2 . HBr 276 121.5 and 130.4
NH2
CH3
O
OCH3
CH3
1. GENERAL INFORMATION
IUPAC Name: 1-(2,5-dimethoxyphenyl)propan-2-amine
CAS#: 2801-68-5
Synonyms: 2,5-DMA; 2,5-dimethoxy-a-methyl-benzeneethanamine;
2,5-dimethoxy-a-methylphenethylamine
Source: DEA Reference Material Collection
Appearance: White powder (HCl and HBr)
UVmax(nm): Not Determined
2. CHEMICAL AND PHYSICAL DATA
2.1 CHEMICAL DATA
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The Drug Enforcement Administrations Special Testing and Research Laboratorygenerated this monograph using structurally confirmed reference material.
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3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Method NMR D2O
Sample Preparation: Dilute analyte to ~10 mg/mL in D2O containing TSP for 0 ppm reference and maleicacid as quantitative internal standard.
Instrument: 400 MHz NMR spectrometerParameters:
Spectral width: at least containing -3 ppm through 13 ppm Pulse angle: 90o Delay between pulses: 45 seconds
Chemical Shift (ppm)8 7 6 5 4 3 2
0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
3216111
Maleic Acid
TSP
1H NMR: 2,5-dimethoxyamphetamine HCl Lot # AKB29A
Chemical Shift...
6
Chemical Shift (ppm)
0
0.25
0.50
0.75
111
Chemical Shift (p...
3
Chemical Shift (ppm)
21
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The Drug Enforcement Administrations Special Testing and Research Laboratorygenerated this monograph using structurally confirmed reference material.
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[x 105
]In
tens
ity
0.5
1.0
1.5
2.0
2.5
3.0
44
51 65 77 91 108 121 13
7
152
164
180
195
EI+
EI Mass Spectrum: 2,5-dimethoxyamphetamine HCl Lot # AKB29A
3.2 Gas Chromatography/Mass Spectrometry
Sample Preparation: Dilute analyte ~1 mg/mL base extracted into chloroform.
Instrument: Agilent gas chromatograph operated in split mode with MS detector
Column: DB-1 MS (or equivalent); 30m x 0.25 mm x 0.25mm
Carrier Gas: Helium at 1 mL/min
Temperatures: Injector: 280oC
MSD transfer line: 280oC MS Source: 230oC MS Quad: 150oC Oven program: 1) 100oC initial temperature for 1.0 min 2) Ramp to 300oC at 12oC/min 3) Hold final temperature for 9.0 minInjection Parameters:
Split Ratio = 20:1, 1mL injectedMS Parameters: Mass scan range: 30-550 amu Threshold: 100 Tune file: stune.u Acquisition mode: scanRetention Time:
8.077 min
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The Drug Enforcement Administrations Special Testing and Research Laboratorygenerated this monograph using structurally confirmed reference material.
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3.3 INFRARED SPECTROSCOPY (FTIR)Insrument: FTIR with diamond ATR attachment (3 bounce)Scan Parameters: Number of scans: 32
Number of background scans: 32Resolution: 4 cm-1
Sample gain: 8Aperture: 150
Wavenumber (cm-1)3500 3000 2500 2000 1500
%Tr
ansm
ittan
ce
20
30
40
50
60
420459
590704
737820
891928
10051036
11131180
1225131313921439
15021603
2513
27892835
3165
Wavenumber (cm-1)1700 1600 1500 1400 1300 1200 1100 1000 900 800 700
%Tr
ansm
ittan
ce
24
32
40
48
56
64
72
420459
590
704737
820
891928
1036
1113
11801225
131313921439
1502
1603
FTIR ATR (Diamond, 3 Bounce): 2,5-dimethoxyamphetamine HCl Lot # AKB29A
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The Drug Enforcement Administrations Special Testing and Research Laboratorygenerated this monograph using structurally confirmed reference material.
Page 5 of 5SWGDRUG.org/monographs.htmLatest Revision: 12/16/2013
http://en.wikipedia.org/wiki/Dimethoxyamphetamine
http://forendex.southernforensic.org/index.php/detail/index/169
4. ADDITIONAL RESOURCES
Forendex
Wikipedia