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35 MCQ Pharmacology

15 MCQ Pharmaceutics &Biopharmaceutics

5 MCQ Pharmacy calculation

15 MCQ Pharmacy Practices & ClinicalPharmacy

70 Total

1-70!"#$%&'(MCQ)-*$+,"$$" .// ,24 ) !

!+ 6'( &4& ;!

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also #00 $its% And Classications from 'ippincott (th)ditionare must, without classication u can *e in trou*le+ so *ecareful

All you need to clarify the concept about all dugs neer use rattafication !ethod

because !ost of the "uestions are t#isted$%his "uestions co!e to !e and other phar!acist in the sa!e day in &ubai and 'ta(e ti!e on #ritten )uestion and arranged and select true choice$

*ood luc( !y friends and please as( *od for help !e in !y life%han(s for all

The action of histamine is :

a-capillary constriction b-elevation of bloodpressurec-stimulation of gastric secretion

d-skeletal muscle paralysis e-slowing the heart rate

One of the following antibiotics is resistant to penicillinase :a-penicillin V b-penicillin Gc-oxapen d-ampicilline-amoxicillin

nderal is :a-similar in action to ergotamineb-similar in action to tubocurarinec-used as an antihistamine

d-pure b -adrenergic receptor blocker

!hich of the following is non selective b" blocker #a-labitolol b-tera$osinec-cloridine d-captoprile-verapamil

%rythroped & :a-is e'ective against G (ve )occib-is a macrolide antibioticc-can increase g*i*t* motilityd-could be used in pregnant women if neede-all of the above

+or the treatment of anaphylactic shock use :

a-salbutamol b-diphenhydraminec-aceta$olamide d-epinephrinee-aminophylline

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-./ 12345

67/.89: . ?@29 89: The mechanism of action of atropine is :a-muscarinic antagonist b-muscarinic agonistc-nicotinic antagonist d-nicotinic agoniste-non of the above

,yocardial muscle tissue property to generate electrical is :a-inotropy b-chronotropyc-automaticity d-contractilitye-non of the above .romotropic e'ect

&denosine is used for :a-ventricular arrythmias b-atrial bradycardiac-supraventricular tachycardiad-supraventricular bradycardiae-non of the above

!hich of the following is responcible for bu'ering

a-magnesium b-chloridec-bicarbonates d-potassiume-troponin

The term shock signi/es :a-hyperperfusion b-hypoperfusion c-tachycardiad-bradycardia e-non of the above

the amount of water in adult male is about:a-012 b-342 c-542 d-"42e-"62

!hich of the following are causes of oedema#a- ncrease hydrostatic pressureb- .ecrease oncotic pressure

c-capillary permeabilityd- a and b e- a 7 b and

8atients prescribed non reversible monoamine oxidase inhibitorshould be advised not to consume food containing tyraminebecause this combination causes:a-postural hypotension b-hallucinationsc-anaphylactic shock d-muscle weakness andtremor e-acute adrenergic crisis including severhypertention

)oncerning )O9 0 inhibitors 7 which is OT true#a-they have lower risk gastric adverse reactionsb-good evidence about their e'ectiveness

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c-cardiac toxicity is a recent concern of this classd-they usually administrated twice dailye-combination with non selective agents give more e'ectiveaction

n the treatment of osteoporosis which of the following is OT

true#a-alendronate should be taken 34 min* before breakfastb-)a and vit* . are essentialc-hormone replacement therapy should be consideredd-outcome should be assessed with periodic bone densitye-raloxifeno is selective oestrogen modulator

!hich of the following is the /rst choice in acute gout#a-allopurinol b-indomethacinc-colchicine d-probencid e-

sul/nylpyra$one%arly symptoms of aspirin poisoning are :a-lethergy ; fatigue b-skin rash ; headachec-throbbing headache ; di$$inessd-uid retention hypotensione-ringing in the ears ; blurred vision

& disease modifying drugs in rheumatoid arthritis:a-gold preparationsb-hydroxychloro

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a-naloxone b-bethidine c-morphine

d-celecoxib e-naproxen

!hat is a maAor contraindication to the use of an OT)sympathomimetic drug

a-gastric ulcer b-uncontrolled hypotension

c-severe asthma d-rheumatoid arthritis

e-hypertension

!hen concidering drug therapy for hypertention 7 which is true#

a-combination of drugs always preferred

b-hydrala$ine is /rst line therapy in young hypertension

c-furosemide should be administrated before meal to improveabsorption

d-beta-blokers should be avoided in asthmatic patient

e- &)%s are recommended in pregnant women

!hich of the following is OT used in theophylline toxicitymanagement :

a-symptomatic control of sei$ures with ben$odia$epine

b-activated charcoal to enhance eliminationc- b blocker for tachycardia

d-control vomiting with metoclopramide

e-methylphenidate to reduce excessive sedation

The antimalarial to be avoided in glucose-3-phosphatedehydrogenase de/ciency :

a-prima

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d-the solvent and solute can be separated by /ltratione-solute doesnBt precipitate as time passes

which of the following need /ltration before V infusion

a- mannitol b- dextrose 12c- insulin

d- >uspension e- emulsion

to increase duration of lidocaine in anasethia

a- propranolol b- succinyl choline c- epinephrine

d- &tropine

which of the following are characteristic for %rythrosine:

a-not e'ective against G(ve cocci

b- has amino glycoside antibiotic

c-decrease GT motility

d-should not be used in pregnant woman if need

e-should be used in pregnant woman if need

which of the following has aldosterone antagonist e'ect

a- amiloride b- furosemidec- spironolactone d- hydrochlorothia$ide

)hiral molecule mean:-

a-dipole moment b- solubilityc- chelating prep* d-optical activity*

lovastatin produce action through:-C,G-co reductase inhibitor*

D

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Een$odia$epine mechanism through:-bindinsubunit of G&E&-& receptor*

most common process for sterili$ation:-

a- /ltration b- dry heatc- moist heat

which of the following need serum level monitoringwith Fuinidine:-

a-.igoxin b- albutrolc-ampicillin ""3-drug used for ttt of migraineand CT:-

a-clonidine b- minoxidilc- propranolol d- hydrala$in

normal water can be used in:-a- parentral prep* b-ophthalmic prep*

c- oral susp* d-external prep*

%cothiophate mechanism through:-

a-binding to muscarinic receptor b- cholinergicantagonist

c- make complex with acetylcholinesterase and inhibit its action

if a drug has the same active ingredient like other drug but notcontain the same inactive ingredient this mean :-

a- Eioe

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c- &sthmatic pt

&ll the following are side e'ect of oral contraceptive except:-

a-hypertension b-weight gain

c- Cyperglycemia d- di$$iness e- constipation

phenytoin act on voltage gated a channel blocker

>&.s produce action through:-

decrease prostaglandin synthesis

which of the following not characteristic of theophylline:-

a- relaxation to brochial smooth muscleb- increase cardiac contractility7 )O

c- nausea 7 abdominal disturbance

e- convulsion

d- sedation

what is drug of choice in ttt of bronchospasmIasthma:-

a-salbutamol =albutrol @ b-theophylline c-propranolol

d-esmolol e-

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which of following tricyclic antidepressant is tertiary amine#

&mitriptyline

antihypertensive used in pregnancy #

&lpha ,ethyldopa

= G,8@ mean:- Good ,anufacturing 8ractice

a-Good ,anufacturing 8rotocol

b-Good ,anu factor 8roduct

c-General ,anufacturing 8rotocol

d-General ,anufacturing 8roduct /DE: F :GHIJ:

deltia$em ; nifedipine ;ocdipine act as

- block )a to intracellular ; increase metabolism from storage site

!hich of the following drug has side e'ect lupus like syndrome :

a- lidocaine b-minoxdile

c- procainamide d-hydrochlorothia$ide

&mpicilline has similar action of:-

a- tetracycline b-cephalexin

c-cloramphinicol d-amikacine

&mphetamine act as :-=.L%)T-&)TG &.L%%LG) &GO>T@

propencid increase the con* Of penicillin through :-

a-increase renal tubular reabsorption

b-decrease renal excretion

c-decrease hepatic metabolism

,ecanism of action of Tri cyclic antidepressant:-

>erotonin ; % Leuptake nhibitor

sopretrenol is :-

a-alpha ;beta agonist b-alpha blocker

c- alpha agonist d-beta agonist

e-beta blocker

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,echanism of action of echothiophate:-

= +orm stable complex which cholinesterase en$yme @

=ndirect-&cting )holinergic &gonists @

=&nticholinesterases MirreversibleN @

a picosulfate is used for KlaxativeK**

.opamine is used in cardiac shock as:-

a@ increase lung performance b@ decrease)*O*8* c@ .ont inducepreiphral vasoconistriction d@ dec*force of contraction

e@ selective dilate renal ; mesenteric

Verapamil can increase e'ect of =theophylline ;carbama$epne;digoxinK*@ as a liver en$yme inhibitor

dipivefrene is:- epinephrine analoug used in glaucoma

enkefaline as peptide used in :-

a-electrical conduction as neuron transmitter

b-similar in action to morphined-KKKKKKKKKKKKKK

anextrapyramidal adverse e'ects is caused by the blocking of:-

a->erotonin receptors in the brain

b-&cetylcholine receptors in the brain

c-.opamine receptors in the brain

d-.opamine receptors outside the brain

!hich of the following are side e'ects of phenytoin treatment#

a-&cne

b-Cirsuitism

c-Gingival hyperplasia

d-a7b7and c

&ll These drugs can be used for 8arkinsonism except :

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a- >elgitine C)?

b- )arbidopa

c- 8ergolide

d- edocromil >od*

)ardiac arrest could be managed by the following except :-

a- %phedrine

b- ?docaine

c- 8ropranolol

d- ormal saline

&ll These drugs are anti-bacterial except :-

a- Palcitabineb- ?omeoxacin

c- )efpra$one

d- on of the above

!hich one of the following has vasodilator e'ect :-

a- icotine

b- )holestyramin

c- urikinase

d- Vit* &&ll of the following are controlled drugs except :

a- Livotril

b- %panutin

c- >resolid

d- .ia$epam

!hich one of the symptoms does not occur with morphine :

a- .iarrhea

b- Lespiratory depression

c- )onstipation

d- Vomiting

!hich one of these drugs is not used for acute pain :-

a- aproxen

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b- )olchicine

c- )odeine

d- 8rednisolone

!hich of the following is not cardio speci/c Q-blocker#

a &tenolol*

b &cebutolol*

c >atolol*

d ?abetalol*

procainamide is like:

a trong >&.s*

c &spirin*

.rug which decreases Santidote the action of warfarin is:

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a )arbima$ole*

b Oral contraceptive*

c 8henobarbitone*

d Vitamin U*

e Give the antidote of each of the following drugs*

Ceparin -8rotomin Pinc*

8aracetamol -&cytylcystiene*

!arfarin -Vitamin U*

The antidote of heparin available in /sh is:

8rotamin sulphate*

Cepatotoxicity is induced due to these drugs except:

a Lifampicin*

b Uetocona$ole*

c Fuinolones*

d .ipyridamole*

The cause of death in morphine toxicity is:

a Lespiratory failure*

b Ceart block*

c &-V block*

8seudomembranous colitis is a side e'ect of:

a )lindamycin*

b Vancomycin*

c Leserpine*

d C*

&ll of these are antimetabolites =cytotoxic@ except:

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a ,ethotrexate*

b )ytarabin*

c &$athioprine*

d ,ercaptopurine*

e +luorouracil*

f )yclophosphamide*

>peci/c >erotonin reuptake inhibitors are used as:

a &ntihistaminic*

b &ntidepressant*

c &ntihypertensive*d &nti-emetic*

+luoxatine =8ro$ac@ is:

>>L antidepressant*

a >elective >erotonin Leuptake nhibitor*

b & ; E*

!hich one is correct#

a .ia$epam is not used for long time*

b .ia$epam is taken *,* only*

c .ia$epam is derived from morphine*

d .ia$epam can cause muscle spasm*

>ource of human insulin is %-coli by:

a Eiosynthetically by recombinant .& technology using %-coli*

b >emi synthetically by en$ymatic modi/cation of protein material*

c & ; E are correct*

The steady state concentration of the drug in the plasma dependson:

a .irect proportion to the rate of elimination*

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b ndirect proportion to the rate of elimination*

c .irect proportion to the rate of administration*

d ndirect proportion to the rate of administration*

)lonididne used in:

a Cypertension*

b Cypotension*

c one of the above*

>ustained release tablets depend on:

8C of stomach*

Treatment with an anti arrhythmic drug depends on the followingexcept:

a 8atient sex*

b Type of medication*

c 8eriod of medication*

d .octors advise*electrical property which produce impulses called :

a-conduction b-automaticity

c-velocity d- excitability

infusion of hypotonic solution in blood cause :

a) shriniking of blood cell

b) hemolysis

c) hyperglycemia

hypoglycemiae) b + d

About definition of first pass effect , it increase with:-

a- increase rate of absorption

b- increase biotransformation

c- increase pka

d- A&

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metal used in rheumatoid arthiritis : gold

in hypodyna!ic shoc( treat!ent #e used +,a, dopa!ineb, nicotine

c, aspirin

!ipivefrine is:-

a-Anti "#$ b-chelating agent

c-%laucoma

Khich of the following Lot occur in digitalis toMicityNOa@hypokalemia b@hypomagnesiac@hypocalcemia

d@hypothyroidism e@impaired kidneyfunction%

the main cause of digitalis toxicity isrenal failure)

-ifty !icrogra!s e"uals+a,.//// 0 nanogra!es 12 b, /$/. 0 !illigra!s 12c, /$///. g

d, a and be, a and c

!c g + 3/// nano g !illi g + 3/// !c g g + 3/// !g g + 3////// !c g456 can prepare 3// !l of 378 9g:l by ta(ing2

a,37!l of 9*:; dissole in 3// !l #aterb,37 g! of 9*:; dissole in 3// !l #aterc,37!l of 9*:; dissole in 3/// !l #aterd,

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sucrose is C7$ gD!ole1 is+

A$ 7$3EC F 3/,pp!G$7$3EC pp!:$7$3ECg!D!l:$ Goth A and G&$ Goth Gand :

pp! concentration = !ass in !g D olu!e in liters!ass 0#t 1 = !ole H !#t = g!

!ass=@$.B3/,@BC7$=7$3ECB3/,g!I JKLMN OPQ!g RS TUN RVWX3///=7$3EC !g Y \ olu!e=3liter]ZRVWX]MRVWX G$7$3EC pp!the phar!acological property of a!pheta!ine is+

A$ :auses release of estrogen$G$ :auses release of stored norepinephrine$:$ &oes not cross the blood brain barrier$&$ :auses the release of stored acetylcholine$^$ 9etaboli_ed by phosphodiesterase ''*cushing - like syndrome is due toa@ adrenal hyperplasia b@ adrenal hypoplasiac@ Cypothyroidism d@ hyperthyroidismThe following properties are similar for both solutions andsuspensions:

&* The components of both solutions and suspensions can beseparated from eachother by physical processes* *5* >olutions and suspensions are composed of two or morecomponents*)* >olute in the solutions and suspensions settle out over a periodof time*.* Eoth & and E

One of the statement considering TetracaineOne of neuro muscular blocker-

n the ttt of T*E-Opioid analgesic-Vit d metabolite-The most one of choice in spinal anaesthesia

*The antimalarial to be avoided in glucose-3-phosphatedehydrogenase de/ciency :

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a- prima