7 principles of haccp. hazard ??? a biological, chemical, or physical agent in food with the...

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7 Principles of HACCP Slide 2 HAZARD ??? A biological, chemical, or physical agent in food with the potential to cause an adverse health effect (Codex, 1997). Hazard: MicrobiologicalMicrobiological ChemicalChemical PhysicalPhysical Food-borne disease (FBD): penyakit menular atau keracunan yang oleh mikroba atau agen yang masuk ke dalam tubuh melalui makanan yang di konsumsi (WHO). Slide 3 Principle 1: Hazard analysis The process of collecting and evaluating information on hazards and conditions leading to their presence to decide which are significant for food safety and should be addressed in the HACCP plan. The process of collecting and evaluating information on hazards and conditions leading to their presence to decide which are significant for food safety and should be addressed in the HACCP plan. Slide 4 Information needed for hazard analysis the agents that could be present in the food under study the severity of the effects and the likelihood of their occurrence the levels that could cause adverse health effects the conditions that could lead to unacceptable levels Slide 5 Slide 6 Microbial Hazards Dangerous microorganisms that cause food-borne disease (FBD): Dangerous microorganisms that cause food-borne disease (FBD): Bacteria Moulds Viruses Parasites Slide 7 Patogenic microorganisms are the MAJOR SOURCES of food contamination!!! Slide 8 Major bacteria causing FBD Aeromonas sppAeromonas spp Bacillus cereusBacillus cereus Brucella spp.Brucella spp. Camphylobacter jejuniCamphylobacter jejuni Clostridium botulinumClostridium botulinum Clostridium perfringensClostridium perfringens Escherichia coliEscherichia coli Listeria monocytogenesListeria monocytogenes Mycobacterium bovisMycobacterium bovis Salmonella spp.Salmonella spp. Shigella spp.Shigella spp. Staphylococcus aureusStaphylococcus aureus Vibrio choleraeVibrio cholerae Vibrio parahaemolyticusVibrio parahaemolyticus Vibrio vulcanificusVibrio vulcanificus Yersinia enteroliticaYersinia enterolitica Slide 9 Some toxigenic moulds causing FBD Aspergillus spp Fusarium spp. Penicilium spp Producing mycotoxins, such as aflatoxin, ochratoxin, etc. Main sources: fruits, nuts and grains Slide 10 Mycotoxins Slide 11 Major viruses causing FBD Hepatitis A and E viruses Hepatitis A and E viruses Small round structured viruses (e.g. Norwalk) Small round structured viruses (e.g. Norwalk) Rotavirus Rotavirus Polio virus Polio virus Slide 12 AnisakisAnisakis AscarisAscaris Clonorchis sinensisClonorchis sinensis CryptosporodiumCryptosporodium Cyclospora catetanensisCyclospora catetanensis DiphyllobothoriumDiphyllobothorium EchinococcusEchinococcus Entamoeba histolyticaEntamoeba histolytica Fasciola hepaticaFasciola hepatica GiardiaGiardia Opisthorcis felineusOpisthorcis felineus Opisthorcis viverriniOpisthorcis viverrini SarcosporodiumSarcosporodium TaeniaTaenia ToxoplasmaToxoplasma TrichinellaTrichinella Major parasites causing FBD Slide 13 Bacterial growth curve Slide 14 Food-Borne Disease Bacteria InfectionInfection Invasion of bacteria and theirs multiplication within the body.Invasion of bacteria and theirs multiplication within the body. E.g.: Salmonella, Campylobacter, E. coli, V. parahaemolyticus, V. cholerae, Y. enterolitica, L monocytogenesE.g.: Salmonella, Campylobacter, E. coli, V. parahaemolyticus, V. cholerae, Y. enterolitica, L monocytogenes IntoxicationIntoxication Caused by consuming toxin produced in food.Caused by consuming toxin produced in food. E.g.: Bacillus cereus, C. botulinum, S. aureus, E. coliE.g.: Bacillus cereus, C. botulinum, S. aureus, E. coli Slide 15 Example: 1. Salmonella Causing SalmonellosisCausing Salmonellosis Main symptoms: diarrhea, fever, vomiting, abdominal cramps.Main symptoms: diarrhea, fever, vomiting, abdominal cramps. Persons at high risk: young, old, pregnant woman, underlying disease states.Persons at high risk: young, old, pregnant woman, underlying disease states. Incubation period: 12 36 hIncubation period: 12 36 h Sources: meat, poultry, milk, eggs, vegetables, shellfish, spices and herbs, untreated water.Sources: meat, poultry, milk, eggs, vegetables, shellfish, spices and herbs, untreated water. Salmonella is heat sensitiveSalmonella is heat sensitive Pasteurization (70 o C for 2 min) is sufficient to kill Salmonella in high moisture foods.Pasteurization (70 o C for 2 min) is sufficient to kill Salmonella in high moisture foods. Slide 16 2. Camphylobacter Causing camphylobacteriosisCausing camphylobacteriosis Symptoms: fever, nausea, diarrhea, abdominal crampSymptoms: fever, nausea, diarrhea, abdominal cramp Person at high risks: babies, debilitated peoplePerson at high risks: babies, debilitated people Incubation: 2-5 daysIncubation: 2-5 days Heat sensitiveHeat sensitive Major sources: frozen foods (meats and poultry).Major sources: frozen foods (meats and poultry). Slide 17 Minimum infective dose L. monocytogenes High (100/g of food) Salmonella (excluding S. typhi) 10 6 Salmonella typhi 10 100 Camphylobacter About 500 Slide 18 Minimum toxic doses of bacterial toxins S. aureus: 10 6 (cells/g)S. aureus: 10 6 (cells/g) C. botulinum: 10 4 - 10 5C. botulinum: 10 4 - 10 5 B. cereus: 10 7 10 8B. cereus: 10 7 10 8 Slide 19 Temperature range for the growth of patogenic bacteria Slide 20 Temperature range for the growth of toxigenic moulds Slide 21 Prevention of FBD Slide 22 Chemical Hazards Pesticides: PCBs, organochlorinPesticides: PCBs, organochlorin DioxinsDioxins Heavy metals: Cd, Hg, PbHeavy metals: Cd, Hg, Pb Metals: Al, Se, etc.Metals: Al, Se, etc. Food additivesFood additives Natural contaminantsNatural contaminants DesinfectantsDesinfectants MycotoxinsMycotoxins Etc.Etc. Slide 23 Hazard Determination Is the presence of agent in raw material probable? Is the presence of agent in line or environment probable? Is an unacceptable survival, persistence or increase at this step probable? Is an unacceptable contamination at this step probable? Is reduction, if any at a further step adequate? YES No Hazard NO HAZARD Slide 24 Menentukan signifikansi bahaya Tingkat keseriusan bahaya (severity): Tingkat keseriusan bahaya (severity): Severity dapat ditetapkan dengan melihat seberapa jauh dampaknya terhadap kesehatan konsumen dan dampak terhadap pencitraan industri. Frekuensi terjadinya bahaya: Risiko tinggi: cenderung terjadi Risiko sedang: dapat terjadi Risiko rendah: cenderung tidak terjadi Slide 25 Menentukan signifikansi bahaya Matrix Risk (UNEP, 2002) Slide 26 Matriks Risiko Boevee (Hermawan, 2005) Risk ranking scheme based upon severity of risk (S) and probability of hazard (P) Severity of hazard (S) Probability of occurrence (P) UnlikelyOccasionallyProbableCommon (1)(2)(3)(4) Very High (4) 5678 High (3) 4567 Medium (2) 3456 Low (1) 2345 Slide 27 Mikroorganisme Patogen Bahaya Tinggi Bahaya Sedang Bahaya Rendah Clostridium botulinum Clostridium botulinum Shigella dysenteriae Shigella dysenteriae Salmonella typhy Salmonella typhy Salmonella paratyphy Salmonella paratyphy Trichinella spiralis Trichinella spiralis Vibrio cholerae Vibrio cholerae Listeria monocytogenes Listeria monocytogenes Camphylobacter jejuni Camphylobacter jejuni Salmonella spp. Salmonella spp. Shigella spp. Shigella spp. Streptococcus pyrogenes Streptococcus pyrogenes Yersinia enterolytica Yersinia enterolytica Hepatitis A dan E Hepatitis A dan E Aeromonas spp. Aeromonas spp. Rotavirus Norwalk Rotavirus Norwalk Vibrio parahaemolyticus Vibrio parahaemolyticus Bacillus cereus Bacillus cereus Clostridium perfringens Clostridium perfringens Staphylococcus aureus Staphylococcus aureus Taenia saginata Taenia saginata Sumber: Winarno & Suroto (2002) Slide 28 Contoh Produk dengan Berbagai Tingkat Risiko Risiko Tinggi Risiko Sedang Risiko Rendah Daging Daging Ikan mentah Ikan mentah Produk-produk olahan Produk-produk olahan susu. susu. Produk dengan nilai pH Produk dengan nilai pH 4.6 atau diatasnya 4.6 atau diatasnya Produk-produk yang Produk-produk yang mengandung ikan, mengandung ikan, daging, telur, sayur, daging, telur, sayur, serealia. serealia. Produk-produk kering dan Produk-produk kering dan produk beku (ikan, daging, produk beku (ikan, daging, telur, sayuran, serealia) telur, sayuran, serealia) Sandwich, pie daging Sandwich, pie daging Produk berbasis lemak Produk berbasis lemak (margarine, coklat, (margarine, coklat, mayonaise, salad mayonaise, salad dressing) dressing) Produk dengan pH di Produk dengan pH di bawah 4.6 (asam) bawah 4.6 (asam) Produk dengan kadar Produk dengan kadar gula tinggi (selai, sirup, gula tinggi (selai, sirup, dll) dll) Produk produk Produk produk konfeksioneri konfeksioneri Minyak Minyak Slide 29 Principle 2: determine the CCPs CCP: CCP: a step at which control can be applied and the step is essential to prevent and eliminate a food safety hazard or reduce it to an acceptable level (Codex 1997). CCPs relate to control of significant food safety hazards only. CCPs relate to control of significant food safety hazards only. Slide 30 2. Determination of CCPs Q1. Is it likely that the raw material contains the hazard under study at unacceptable levels? Q2. Will processing, including expected consumer use, eliminate the hazard or reduce it to an acceptable level? Critical control point decision tree Questions to be asked for each raw material used Questions to be asked for each raw material used YES NO YES Not CCP CCP for the raw materials for this hazard Slide 31 Questions to be asked for each process stage (SNI, 1998) Slide 32 Control Measure Any factor or activity which can be used to prevent, eliminate, or reduce food safety hazards to an acceptable level. Any factor or activity which can be used to prevent, eliminate, or reduce food safety hazards to an acceptable level. Control measures are specific for each hazard and can be either process or activities. Control measures are specific for each hazard and can be either process or activities.

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