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*Asthma images by Peter Jeffery* . ........ ; MEF 50%/ MIF 50%. ( ); ( ) ( ); ( )*Pathological changes in asthmaThis slide highlights the morphological changes of airways in asthma patients compared with the airways of normal patients.Variable airflow obstruction and bronchial hyperreactivity (specific and non-specific) are central features in asthma.Post-mortem examinations of patients who have died during status asthmaticus have revealed extensive inflammatory changes of the airway involving the mucus glands, epithelium, and basement membrane.

Cotran RS et al. Robbins Pathologic Basis of Disease. 6th edn. Philadelphia: WB Saunders, 1999:697755.Kavuru NS, Wiedemann HP. Diagnosis and Management of Asthma. 2nd edn. Caddo: Professional Communications, 1998:3340.