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Page 1: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

254

Chapter.8

Bibliography

Page 2: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

255

A

Abuja PM, Albertini R. Methods for monitoring oxidative stress, lipid peroxidation and

oxidation resistance of lipoproteins. Clin Chim Acta 2001;360:1-17.

Abul-Ezz SR, Walker PD, Shah SV. Role of glutathione in an animal model of

myoglobinuric acute renal failure. Proc Natl Acad Sci U S A 1991;88:9833-9837.

Ackermann D, Heinsen HA. Uber die physiologische Wirkung des Asterubins und anderer,

zum Teil neu dargestellter, schwefelhaltiger Guanidinderivate. Hoppe Seyles Z Physiol

Chemie 1935; 235: 115–121.

Aebi H. Catalase in vitro, Methods Enzymol 1984;105:121– 126.

Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MF. Phosphorylation of

Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and

inhibits insulin action. J Biol Chem 2002;277:1531-1537.

Alexandraki K, Piperi C, Kalofoutis C, Singh J, Alaveras A, Kalofoutis A. Inflammatory

process in type 2 diabetes: the role of cytokines. Ann NY Acad Sci 2006; 1084:89-117.

Allen DW, Schroeder WA, Balog J. Observations on the chromatographic heterogeneity of

normal adult and fetal human hemoglobin. J Am Chem Soc 1958;80:1628– 34.

Alvestrand A, Majagic M, Wajngot A, Efendic S. Glucose intolerance in uremic patients: The

relative contributions of impaired β-cell function and insulin resistance. Clin Nephro

1989;31:175-183.

Alvestrand A. Carbohydrate and insulin metabolism in renal failure. Kidney Int 1997;62:S48-

S52.

Amann K, Koch A, Hofstetter J, Gross ML, Haas C, Orth SR, Elmke H, Rump LC, Ritz E.

Glomerulosclerosis and progression: effect of subantihypertensive doses of alpha and beta

blockers. Kidney Int 2001;60:1309-1323.

Ames DNA damage from micronutrient deficiencies is likely to be a major cause of cancer.

Mutat Res 2001;475:7-20.

Anderson RA, Polansky MM. Tea enhances insulin activity. J Agric Food Chem

2002;50:7182-7186.

Annuk M, Zilmer M, Lind L, Linde T, Fellstrom B. Oxidative stress and endothelial function

in chronic renal failure. J Am Soc Nephrol 2001;12:2747–2752.

Annukk M, Zilmer M, Fellstrom B. Endotehlium-dependent vasodilation and oxidative stress

in chronic renal failure: Impact on cardiovascular disease. Kidney Int Suppl 2003;84:50-53.

Page 3: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

256

Anuradha CV, Balakrishnan SD. Taurine attenuates hypertension and improves insulin

sensitivity in the fructose-fed rat, an animal model of insulin resistance. Can J Physiol

Pharmacol 1999; 77: 749–754.

Arici M, Walls J. End-stage renal disease, atherosclerosis, and cardiovascular mortality: Is C-

reactive protein the missing link? Kidney Int 2001;59:407–414.

Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G,

Olefsky J, Karin M.. IKK-beta links inflammation to obesity-induced insulin resistance. Nat

Med 2005;11:191-198.

Aronis A, Madar Z, Tirosh O. Mechanism underlying oxidative stress-mediated lipotoxicity:

Exposure of j774.2 macrophages to triacylglycerols facilitates mitochondrial reactive oxygen

species production and cellular necrosis. Free Radic. Biol. Med. 2005;38:1221–1230.

Arguelles S, Garcia S, Maldonado M, Machado A, Ayala A. Do the serum oxidative stress

biomarkers provide a reasonable index of the general oxidative stress status? Biochim

Bipphys Acta 2004;1674:251-259.

Arsie MP, Marchioro L, Lapolla A. Evaluation of diagnostic reliability of DCA 2000 for

rapid and simple monitoring of HbA1C. Acta Diabetol 2000;37:1– 7.

Asante-Appiah E, Kennedy BP. Protein tyrosine phosphatases: the quest for negative

regulators of insulin action. Am J Physiol Endocrinol Metab 2003;284:E663-670.

Aso Y. Cardiovascular disease in patients with diabetic nephropathy. Curr Mol Med. 2008;

8:533-43.

Auroma OI, Halliwell B, Hoey BM, Butler J. Antioxidant action of taurine, hypotaurine and

their metabolic precursors. Biochem J 1988;256:251-255.

Auroma OI, Halliwell B, Gajewski E, Dizdaroglu M. Copper-iron dependent damage to bases

in DNA in the presence of hydrogen peroxide. Biochem J 1991;273:2601-2604.

Axelsson J, Qureshi AR, Sulinan ME. Truncal fat mass as a contributor to inflammation in

end-stage renal disease. Am J Clin Nutr 2004;80:1222–1229.

B

Babu NP, Bobby Z, Selvaraj N, Harish BN. Increased fructosamine in non-diabetic

rheumatoid arthritis patients: role of lipid peroxides and glutathione. Clin Chem Lab Med

2006;44:848-852.

Page 4: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

257

Bak JF, Schmitz O, Sørensen SS. Activity of insulin receptor kinase and glycogen synthase in

skeletal muscle from patients with chronic renal failure. Acta Endocrinol (Copenh)

1989;121:744-750.

Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein

glycation in non-diabetic pediatric nephritic syndrome: possible role of lipid peroxidation.

Clin Chim Acta 2003;337:127-132.

Balamurugan R, Selvaraj N, Bobby Z, Sathiyapriya V. Increased glycated hemoglobin level

in non-diabetic nephrotic children is associated with oxidative stress. Indian J Physiol

Parmacol 2007;51:153-159.

Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM. Increased p85/55/50 expression and

decreased phopshatidylinositol 3-kinase activity in insulin-resistance human skeletal muscle.

Diabetes 2005;54:2351-2539.

Barazzoni R, Biolo G, Zanetti M, Bernardi A, Guarnieri G. Inflammation and adipose tissue

in uremia. J Ren Nutr 2006;16:204-207.

Barford D, Jia Z, Tonks NK. Protein tyrosine phosphatases take off. Nat Struct Biol.

1995;2:1043–1053.

Barnes PJ, Karin M. Nuclear factor κB - a pivotal transcription factor in chronic

inflammatory disease. N Engl J Med 1997;336:1066–1071.

Barrett WC, DeGnore JP, Keng YF, Zhang ZY, Yim MB, Chock PB. Roles of superoxide

radical anion in signal transduction mediated by reversible regulation of protein-tyrosine

phosphatase 1B. J Biol Chem 1999;274:34543–34546.

Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, Soos MA, Maslen GL,

Williams TD, Lewis H, Schafer AJ, Chatterjee VK, O'Rahilly S. Dominant negative

mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus

and hypertension. Nature 1999;402:880–3.

Bastard JP, Maachi M, Van Nhieu JT, Jardel C, Bruckert E, Grimaldi A, Robert JJ, Capeau J,

Hainque B. Adipose tissue IL-6 content correlates with resistance to insulin activation of

glucose uptake both in vivo and in vitro. J Clin Endocrinol Metab 2002;87:2084-9.

Basu S, Kolesnick R. Stress signals for apoptosis: ceramide and c-Jun kinase. Oncogene

1998;17: 3277–3285.

Baumann H, Gauldie J. The acute phase response. Immunol Today 1994;15:74–80.

Baynes JW. Role of oxidative stress in development of complications of diabetes. Diabetes

1991;40:405–412.

Page 5: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

258

Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications: a new perspective

on an old paradigm. Diabetes 1999;48:1– 9.

Beckman JS. Ischemic injury mediator. Nature (Lond.) 1990;345:27–28.

Bemelmans MH, Gouma DJ, Buurmanwa. Influence of nephrectomy on tumor necrosis factor

clearance in murine model. J Immunol 1993;150:2007–2017.

Bender K, Gottlicher M, Whiteside S, Rahmsdorf HJ, Herrlich P. Sequential DNA damage-

independent and –dependent activation of NF-kappaB by UV. EMBO J 1998;17:5170–5181.

Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocytes-secreted protein

Acrp30 enhances hepatic insulin action. Nat Med 2001;7:947-953.

Bergström J, Hultman E. Glycogen content of skeletal muscle in patients with renal failure.

Acta Med Scand 1969;186:989-998.

Benjamin R, Sacks D. Glycated protein update: implications of recent studies, including the

diabetes control and complications trial. Clin Chem 1994;40:683-687.

Besarab A, Levin A. Defining a renal anemia management period. Am J Kidney Dis Suppl

2000;36:S13-S23.

Bertani T, Abbate M, Zoja C, et al. Tumor necrosis factor induces glomerular damage in the

rabbit. Am J Pathol 1989;134:419–430.

Beutler E, Kelley BM. The effect of sodium nitrate on RBC glutathione. Experientia

1963;19:96-97.

Bevan P. Insulin signalling. J Cell Sci 2001;114:1429–30.

Bhagat K, Vallance P. Inflammatory cytokines impair endothelium-dependent dilatation in

human veins in vivo. Circulation 1997;96:3042–3047.

Birdsall TC. Therapeutical application of taurine. Altern Med Rev 1998;3:128-136.

Birnbaum MJ. Turning down insulin signalling. J Clin Invest 2001;108:655-659.

Blair AS, Hajduch E, Litherland GJ, Hundal HS. Regulation of glucose transport and

glycogen synthesis fin L6 muscle cells during oxidative stress. Evidence for cross-talk

between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways. J

Biol Chem 1999;274:36293–36299.

Boaz M, Smetana S, Weinstein T, Matas Z, Gafter U, Iaina A, Knecht A, Weissgarten Y,

Brooks AP, Metcalfe J, Day JL, Edwards MS. Iron deficiency and glycosylated haemoglobin

A1. Lancet 1980;19. ii:141.

Boaz M, Smetana S, Weinstein T, Matas Z, Gafter U, Iaina A, Knecht A, Weissgarten Y,

Brunner D, Fainaru M, Green MS. Secondary prevention with antioxidants of cardiovascular

Page 6: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

259

disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet.

2000;356:1213-8.

Bologa RM, Levine DM, Parker TS, Cheigh JS, Serur D, Stenzel KH, Rubin AL. Interleukin-

6 predicts hypoalbuminemia, hypocholesterolemia, and mortality in hemodialysis patients.

Am J Kidney Dis 1998;32:107–114.

Bolton CH, Downs LG, Victory JGG, Dwight JF, Tomson CR, Mackness MI, Pinkney JH.

Endothelial dysfunction in chronic renal failure: Roles of lipoprotein oxidation and pro-

inflammatory cytokines. Nephrol Dial Transplant 2001;16:1189–1197.

Bone RC. Immunologic dissonance: A continuing evolution in our understanding of the

systemic inflammatory response syndrome and the multiple organ dysfunction syndrome.

Ann Intern Med 1996;125:690–691.

Boring L, Gosling J, Cleary M, Charo IF. Decreased lesion formation in CCR2-/- mice

reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998;394:894–897.

Boveris A, Costa LE, Cadenas E, Poderoso JJ. Regulation of mitochondrial respiration by

adenosine diphosphate, oxygen and nitric oxide. Methods Enzymol 1999;301:188–198.

Bradford M. A rapid and sensitive method for the quantification of microgram quantity of

protein utilizing the principle of protein dye binding. Anal Biochem 1976;72: 248-254.

Brand K, Page S, Walli AK, Neumeier D, Baeuerle PA. Role of nuclear factor-kappa B in

atherogenesis. Exp Physiol 1997;82:297–304.

Brazil DP, Hemmings BA. Ten years of protein kinase B signalling: a hard Akt to follow.

Trends Biochem Sci 2001;26:657–64.

Brenner RR. Endocrine control of fatty acid desaturation. Biochem Soc Trans 1990;18:773–

775.

Brett J, Schmidt AM, Yan SD, Zou YS, Weidman E, Pinsky D, Nowygrod R, Neeper M,

Przysiecki C, Shaw A. Survey of the distribution of a newly characterized receptor for

advanced glycation end products in tissues. Am J Pathol. 1993;143:1699-712.

Broadhurst CL, Polansdy MM, Anderson RA. Insulin-like biological activity of culinary and

medicinal plant aqueous extracts in vitro. J Agric Food Chem 2000;48:849-852.

Brown GC. Nitric oxide and mitochondrial respiration. Biochim Biophys Acta

1999;1411:351–369.

Brownlee M, Cerami A, Vlassara H. Advanced glycosylation end products and the

biochemical basis of diabetic complications. N Engl J Med 1988;318:1315– 21.

Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes

2005;54:1615–1625.

Page 7: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

260

Brunner D, Fainaru M, Green MS. Secondary prevention with antioxidants of cardiovascular

disease in end-stage disease (SPACE): randomised placebo- controlled trial. Lancet

2000;356: 1213-1218.

Bruun JM, Lihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B. Regulation

of adiponectin by tissue-derived cytokines; in vivo and in vitro investigations in humans. Am

J Physiol Endocrinol Metab 2003; 285:E527–E533.

Bui NT, Livolsi A, Peyron JF, Prehn JH. Activation of nuclear factor kappaB and Bcl-x

survival gene expression by nerve growth factor requires tyrosine phosphorylation of

IkappaB alpha. J Cell Biol 2001;152:753–764.

Buren J, Lindmark S, Renstrom F, Eriksson JW. In vitro reversal of hyperglycemia

normalizes insulin action in fat cells from type 2 diabetes patients: Is cellular insulin

resistance caused by glucotoxicity in vivo? Metabolism 2003;52:239–245.

C Caglar K, Peng Y, Pupim LB, Flakoll PJ, Levenhagen D, Hakim RM, Ikizler TA.

Inflammatory signals associated with hemodialysis. Kidney Int 2002;62:1408–1416.

Canaud B, Chenine L, Leray-Moragues H, Wiesen H, Tetta C. Residual renal function and

dialysis modality: Is it really beneficial to preserve residual renal function in dialysis

modality: Is it really beneficial to preserve residual renal function in dialysis patients?

Nephrology 2006;11:292-296.

Carantoni M, Abbasi F, Warmerdam F, Klebanov M, Wang PW, Chen YDI, Azhar S, Reaven

GM. Relationship between insulin resistance and partially oxidized LDL particles in healthy,

nondiabetic volunteers. Arterioscler Thromb Vasc Biol 1998;18:762–767.

Carvalho CR, Brenelli SL, Silva AC, Nunes AL, Velloso LA, Saad MJ. Effect of aging on

insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and

muscle of rats. Endocrinology 1996;137:151-9.

Casparie AF, Miedema K. GLycosylated hemoglobin in diabetes and renal failure. Lancet

1977;2:1833-1835.

Castellino P, AS, Luzi L, Barr JG, Smith DJ, Petrides A, Giordano M, Carroll C, DeFronzo

RA. Glucose and amino acid metabolism in chronic renal failure: Effect of insulin and amino

acids. Am J Physiol 1992;262:F168-F176.

Page 8: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

261

Ceballos-Picot I, Witko-Sarsat V, Merad-Boudia M, Nguyen AT, Thevenin M, Jaudon MC,

Zingraff J, Verger C, Jungers P, Descamps-Latscha B. Glutathione antioxidant system as a

marker of oxidative stress in chronic renal failure. Free Rad Biol Med 1996;21:845–853.

Cecchin E, De Marchi S, Panarello G, De Angelis V. Rheological abnormalities of

erythrocyte deformability and increased glycosylation of hemoglobin in nephrotic syndrome.

Am J Nephrol 1987;7:18-21.

Cefalu WT, Wang ZQ, Bell-farrow A, Ralapati S. Liver and kidney tissue membranes as

tissue markers for nonenzymatic glycosylation. Diabetes 1991;40:902– 7.

Ceriello A, Giugliano D, Quatraro A, Donzella C, Dipalo G, Lefebvre PJ. Vitamin E

reduction of protein glycosylation in diabetes. New prospect for prevention of diabetic

complications? Diabetes Care 1991;14:68-72.

Ceriello A. Is oxidative stress the missing link between insulin resistance and atherosclerosis?

Diabetologia 1995; 38:1484–1485.

Ceriello A. Oxidative stress and glycemic regulation. Metabolism 2000;49:27–29.

Chade AR, Rodriguez-Porcel M, Grande JP. Krier JD, Lerman A, Romero JC, Napoli C,

Lerman LO. Distinct renal injury in early atherosclerosis and renovascular disease.

Circulation 2002;106:1165-1171.

Chakravarthy BK, Gupta S, Gode KD. Functional beta cell regeneration in the islets of

pancreas in alloxan induced diabetic rats by (-)-epicatechin. Life Sci 1982;31:2693-2697.

Chen NG, Azhar S, Abbasi F, Carantoni M, Reaven GM. The relationship between plasma

glucose and insulin response to oral glucose, LDL oxidation, and soluble intercellular

adhesion molecule-1 in healthy volunteers. Atherosclerosis 2000;152: 203–208.

Chen J, Muntner P, Hamm LL, Fonseca V, Batuman V, Whelton PK, He J. Insulin resistance

and risk of chronic kidney disease in nondiabetic US adults. J Am Soc Nephrol 2003;14:469-

477.

Chen M, Robertson RP. Restoration of the acute insulin response by sodium salicylate: a

glucose dose-related phenomenon. Diabetes 1978;27:750-756.

Chen ZJ, Parent L, Maniatis T. Site-specific phosphorylation of IkappaB alpha by a novel

ubiquitination-dependent protein kinase activity. Cell 1996;84:853–862.

Chen X, Scholl TO, Leskiw MJ, Donaldson MR, Stein TP. Association of glutathione

peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. J

Clin Endocrinol Metab 2003;88:5963-5968.

Cheng TO, Green tea, coffee, and diabetes. Ann Intern Med 2006;145:633-4.

Page 9: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

262

Chowdhury TA, Lasker SS. Elevated glycated haemoglobin in nondiabetic patients is

associated with an increased mortality in myocardial infarction. Postgrad Med J 1998;74:480-

481.

Chugh SN, Jain S, Agrawal N, Sharma A. Evaluation of oxidative stress before and after

hemodialysis in chronic renal failure. J Assoc Phys India 2000;48:981– 4.

Chung HY, Yokozawa T, Soung DY, Kye IS, No JK, Baek BS. Peroxynitrite-scavenging

activity of green tea tannin. J Agric Food Chem 1998;46:4484-4486.

Coban E, Ozdogan M, Timuragaoglu A. Effect of iron deficiency anemia on the levels of

hemoglobin A1C in nondiabetic patients. Acta Haematol 2004;112:126-128.

Cohen MP, Wu V-Y. Identification of specific amino acids in diabetic glomerular basement

membrane collagen subject to non-enzymatic glucosylation in vivo. Biochem Biophys Res

Commun 1981;100:1549 – 54.

Cohen P. The structure and regulation of protein phosphatase. Annu Rev Biochem

1989;58:453-508.

Collins T, Cybulsky MI. NF-kappaB: pivotal mediator or innocent bystander in

atherogenesis? J Clin Invest 2001;107:255–264.

Conteras I, Caro JF, Aveledo L, Diaz K, Durrego P, Weisinger JR. In chronic uremia, insulin

activates receptor kinase but not pyruvate dehydrogenase. Nephron 1992;61:77-81.

Cybulsky MI, Gimbrone MAJ. Endothelial expression of a mononuclear leukocyte adhesion

molecule during atherogenesis. Science 1991;251:788–791.

D

D’ Alessandris C, Lauro R, Presta I, Sesti G. C-reactive protein induces phosphorylation of

insulin receptor substrate – 1 on Ser 307 and Ser 612 in L6 myocytes, thereby impairing the

insulin signalling pathway that promotes glucose transport. Diabetologia 2007;50:840-849.

Dandona P, Freedman DB, Moorhead J. Glycosylated Hb in chronic renal failure. Br Med J

1979;i:1183-1184.

Danesh J, Collins R, Appleby P, Peto R. Association of fibrinogen, C-reactive protein,

albumin, or leukocyte count with coronary heart disease: Meta-analyses of prospective

studies. JAMA 1998;279:1477-1482.

Danielski M, Ikizler TA, McMonagle E, Kane JC, Pupim L, Morrow J, Himmelfarb J.

Linkage of hypoalbuminemia, inflammation, and oxidative stress in patients receiving

maintenance hemodialysis therapy. Am J Kidney Dis 2003;42:286–294.

Page 10: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

263

Davie S, Gould B, Yudkin J. Effect of vitamin C on glycosylation of proteins. Diabetes

1992;41:167-173.

Davies KJA. Protein damage and degradation by oxygen free radicals. II Modification of

amino acids. J Biol Chem 1987a;262: 9902-9907.

Davies KJA. Protein damage and degradation by oxygen free radicals. IV Degradation of

denatured proteins. J Biol Chem 1987b; 262: 9914-9920.

Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-252.

de Alvaro C, Teruel T, Hernandez R, Lorenzo M. Tumor necrosis factor-α produces insulin

resistance in skeletal muscle by activation of inhibitor-kB Kinase in a p38 MAPK-dependent

manner. J Biol Chem 2004;279:17070-17078.

De Biase L, Pignatellii P, Lenti L, Tocci G, Piccioni F, Riondino S, Pulcinelli FM, Rubattu S,

Volpe M, Violi F. Enhanced TNF alpha and oxidative stress in patients with heart failure:

effect of TNF alpha on platelet O2− production. Thromb Haemost 2003;90:317–325.

De Boer MJ, Miedema K, Casparie AF. Glycosylated hemoglobin in renal failure.

Diabetologia 1980;18:437-440.

Decsi T, Molnár D, Koletzko B. Lipid corrected plasma α-tocopherol values are inversely

related to fasting insulinaemia in obese children. Int J Obes Relat Metab Disord 1996;20:

970–972.

DeFronzo RA, Tobin JD, Rowe JW, Andres R. Glucose intolerance in uremia: Quantification

of pancreatic beta cell sensitivity to glucose and tissue sensitivity to insulin. J Clin Invest

1978;62:425-435.

DeFronzo RA, Beckles AD. Glucose intolerance following chronic metabolic acidosis in

man. Am J Physiol 1979;236:E328-E334.

DeFronzo RA, Alvestrand A. Glucose intolerance in uremia: Site and mechanism. Am J Clin

Nutr 1980;33:1438-1445.

DeFronzo RA, Alvestrand A, Smith D, Hendler R, Hendler E, Wahren J. Insulin resistance in

uremia. J Clin Invest 1981;67:563-568.

del Aguila LF, Claffey KP, Kirwan JP. TNF-alpha impairs insulin signalling and insulin

stimulation of glucose uptake in C2C12 muscle cells. Am J Physiol 1999;276:E849–E855.

De Marchi S, Cecchin E, Basile A, Donadon W, Lippi U, Quaia P, Tesio F. More on the

increase of hemoglobin A1 in chronic renal failure: the role of acidosis. Nephron 1983;35:49-

53.

Dembe K, Karnafel W, Pacuła P. The effect of age on glucose tolerance and B cell secretion.

Pol Arch Med Wewn 1997;97:112-9.

Page 11: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

264

Demoule A, Divangahi M, Yahiaoui L, Danialou G, Gvozdic D, Labbe K, Bao W, Petrof BJ.

Endotoxin triggers nuclear factor-kappaB- dependent up-regulation of multiple

proinflammatory genes in the diaphragm. Am J Respir Crit Care Med 2006;174:646-653.

Denu JM, Tanner KG. Specific and reversible inactivation of protein tyrosine phosphatases

by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox

regulation. Biochemistry 1998;37:5633–5642.

Descamps-Latscha B, Herbelin A, Nguyen AT, Roux-Lombard P, Zingraff J, Moynot A,

Verger C, Dahmane D, de Groote D, Jungers P. Balance between IL-1β, TNF-α, and their

specific inhibitors in chronic renal failure and maintenance dialysis. Relationships with

activation markers of T cells, B cells, and monocytes. J Immunol 1995;154:882–892.

Descamps-Latscha B, Jungers P, Witko-Sarsat V. Immune system dysregulation in uremia:

role of oxidative stress. Blood Purif 2002;20:481-484.

Devaraj S, Xu DY, Jialal I. C-reactive protein increases plasminogen activator inhibitor-1

expression and activity in human aortic endothelial cells: implications for the metabolic

syndrome and atherothrombosis. Circulation 2003;107:398–404.

De Vega L, Fernandez RP, Martin Mateo MC, Bustamante JB, Herrero AM, Munguira EB.

Glutathione determination and a study of the activity of glutathioneperoxidase, glutathione-

transferase, and glutathione–reductase in renal transplants. Renal Failure 2002;24:421–432.

Diamond GF. Reactive oxygen species and progressive glomerular disease. J Lab Clin Med

1994;124:468-469.

DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive

IkappaB kinase that activates the transcription factor NF-kappaB. Nature 1997;388:548–554.

Digicaylioglu M, Lipton SA. Erythropoietin-mediated neuroprotection involves cross-talk

between Jak2 and NFkappa B signalling cascades. Nature 2001;412:641–647.

Dokshina GA, Silaeva TY, Yartsev EI. Some insulin-like effects of taurine (in Russian).

Vopr Med Khim 1976; 22: 503–507.

Dounousi E, Papavasiliou E, Makedou A, Ioannou K, Katopodis KP, Tselepis A,

Siamopoulos KC, Tsakiris D. Oxidative stress is progressively enhanced with advancing

stages of CKD. Am J Kidney Dis 2006;48:752-60.

Drueke, TB, Khoa TN, Massy ZA, Witko-Sarsat B, Lacour B, Descaps-Latsch B. Role of

oxidized low density lipoprotein in the atherosclerosis of uremia. Kidney Int Suppl

2001;78:S114-S119.

Drueke TB, Rostand SG. Progresssion of vascular calcification in uraemic patients: can it be

stopped? Nephrol Dial Transplant 2002;17:1365-1368.

Page 12: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

265

Dzúric R, Spustová V, Lajdová I. Inhibition of glucose utilization in isolated rat soleus

muscle by pseudouridine: Implications for renal failure. Nephron 1993;65:108-110.

Dzurik R, Valovicova E. Glucose utilization during uremia: In vitro study. Clin Chim Acta

1970;30:137-142.

Dzurik R, Spustova V, Janekova K. The prevalence of insulin resistance in kidney disease

patients before the development of renal failure. Nephron 1995;69:281-285.

Ducluzeau PH. Perretti N, Laville M, Andreelli F, Vega N, Riou JP, Vidal H. Regulation by

insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific

defects in type 2 diabetes. Diabetes 2001;50:1134-1142.

Dunlop ME, Muggli EE. Small heat shock protein alteration provides a mechanism to reduce

mesangial cell contractility in diabetes and oxidative stress. Kidney Int 2000;57,464–475.

E

Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 2005;365:1415-28.

Eckl PM, Ortner A, Esterbauer H. Genotoxic properties of 4-hydroxyalkenals and analogous

aldehydes. Mutat Res 1993;290:183–192.

Eidemak I, Feldt-Rasmussen B, Kanstrup IL, Nielsen SL, Schmitz O, Strandgaard S. Insulin

resistance and hyperinsulinemia in mild to moderate progressive chronic renal failure and its

association with aerobic work capacity. Diabetologia 1995;38:565-572.

El-Agouza I, Abu Shola A, Sirdah M. The effect of iron deficiency anaemia on the levels of

haemoglobin subtypes: possible consequences for clinical diagnosis. Clin Lab Haematol

2002;24:285-289.

El-Ghar SM, Qureshi M, Shoker A, Prasad K. Oxidative stress in renal transplant patients

who develop cardiovascular disease. J Cardiovasc Pharmacol Ther 2006;11:203-10.

Elhage R, Clamens S, Besnard S, Mallat Z, Tedgui A, Arnal J, Maret A, Bayard F.

Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak

formation by 17beta-estradiol in apolipoprotein E-deficient mice. Atherosclerosis

2001;156:315–320.

Elizarova EP, Nedosugova LV. First experiments in taurine administration for diabetes

mellitus – the effect on erythrocyte membranes. Adv Exp Med Biol 1996; 403: 583–588.

El-Rashidy FH, Al-Turk WA, Stohs SJ. Glutathione, glutathione reductase and glutathione S-

transferase activities in erythrocytes and lymphocytes in chronic renal disease. Res Commun

Chem Pathol Pharmacol 1984;44:423-430.

Page 13: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

266

Eppler B, Dawson Jr. R, Dietary taurine manipulation in aged male Fischer 344 rat tissue:

taurine concentration, taurine biosynthesis, and oxidative markers. Biochem Pharm

2001;62:29-39.

Eric DW, Jongsoon L, Lone H, Minsheng Y, Steven ES. Insulin resistance due to

phosphorylation of insulin receptor substrate-1 at serine 302. J Biol Chem. 2004;279, 35298-

35305.

Escriva F, Agote M, Rubio E, Molero JC, Pascual-Leone AM, Andres A, Satrustegui J,

Carrascosa JM. In vivo insulin-dependent glucose uptake of specific tissues is decreased

during aging of mature Wistar rats. Endocrinology 1997;138:49-54.

Esterbauer H, Wag G, Puhl H. Lipid peroxidation and its role in atherosclerosis. Br Med Bul

1993;49:566–576.

Esterbauer H. Cytotoxicity and genotoxicity of lipid oxidation products. Am J Clin Nutr

1993;57:779S–786S.

Evans JL, Goldfine ID: α-Lipoic acid: a multi-functional antioxidant that improves insulin

sensitivity in patients with type 2 diabetes. Diabetes Technol Ther 2000;2:401–413.

Evans JL, Goldfine ID, Maddux BA, Grodsky GM. Oxidative stress and stress-activated

signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 2002;23:599–622.

Evans JL, Heymann CJ, Goldfine ID, Gavin LA: Pharmacokinetics, tolerability, and

fructosamine-lowering effect of a novel, controlled release formulation of α-lipoic acid.

Endocr Pract 2002;8:29–35.

Evans JL, Goldfine ID,Maddux BA, Grodsky GM. Are oxidative stress activated signaling

pathways mediators of insulin resistance and β-cell dysfunction? Diabetes 2003;52:1–8.

Evans JL, Maddux BA, Goldfine ID. The molecular basis for oxidative stress-induced insulin

resistance. Antioxid Redox Signal 2005;7:1040–1052.

F Facchini FS. Effect of phlebotomy on plasma glucose and insulin concentrations. Diabetes

Care 1988;21:2190.

Facchini FS, Humphreys MH, DoNascimento CA, Abbasi F, Reaven GM. Relation between

insulin resistance and plasma concentrations of lipid hydroperoxides, carotenoids, and

tocopherols. Am J Clin Nutr 2000; 72: 776–779.

Page 14: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

267

Fantus G, Kadota S, Deragon G, Foster B, Posner BI. Pervanadate (peroxide(s) of vanadate)

mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase.

Biochemistry. 1989;28:8864–8871.

Felber JP, Meyer HU, Curchod B, Iselin HU, Rousselle J, Maeder E, Pahu P, Jequier E.

Glucose storage and oxidation in different degrees of human obesity measured by continuous

indirect calorimetry. Diabetologia 1981;20:3944.

Festa A, D’Agostiono R, Howard G, Mykk nen L, Tracy RP, Haffner SM. Chronic

subclinical inflammation as part of the insulin resistance syndrome; The Insulin Resistance

Atherosclerosis Study (IRAS). Circulation 2000;102:42–47.

Fiorillo C, Oliviero C, Rizzuti G, Nediani C, Pacini A, Nassi P. Oxidative stress and

antioxidant defences in renal patients. Clin Chem Lab Med 1998;36:149-153.

Fichtscherer S, Rosenberger G, Walter DH, Breuer S, Dimmeler S, Zeiher AM. Elevated C

reactive protein levels and impaired endothelial vasoreactivity in patients with coronary heart

disease. Circulation 2000;102:1000–1006.

Fisher CJ, Agosti JM, Opal SM, Lowry SF, Balk RA, Sadoff JC, Abraham E, Schein RM,

Benjamin E. Treatment of septic shock with the tumour necrosis factor: Fc fusion protein. N

Engl J Med 1996;334:1697–1702.

Fliser D, Pacini G, Engelleiter R, Kautzky-Willer A, Prager R, Franek E, Ritz E. Insulin

resistance and hyperinsulinemia are already present in patients with incipient renal disease.

Kidney Int 1998;53:1343-1347.

Floccari F, Aloisi C, Crascì E, Sofi T, Campo S, Tripodo D, Criseo M, Frisina N, Buemi M.

Oxidative stress and uremia. Med Res Rev 2005;25:473-86.

Fluckiger R, Harmon W, Meier W, Loo S, Gabbay K. Hemoglobin carbamylation in uremia.

N Engl J Med 1981;304:823-827.

Foley RN, Parfrey PS, Sarnak JM. Cardiovascular disease in chronic renal disease. Clinical

epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis 1998;32:S

112-119.

Fong KL, McCay PB, Poyer JL. Evidence for superoxide-dependent reduction of Fe3+ and its

role in enzyme-generated hydroxyl radical formation. Chem Biol Interaction 1976;15:77-89.

Ford ES. The metabolic syndrome and C-reactive protein, fibrinogen, and leukocyte count:

findings from the Third National Health and Nutrition Examination Survey. Atherosclerosis

2003; 168;351–358.

Ford HC, Chew-Lim W, Crooke MJ. Hemoglobin A1C and serum fructosamine levels in

hyperthyroidism. Clin Chim Acta 1987;166: 317-321.

Page 15: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

268

Franconi F, Bennardini F, Mattana A, Miceli M, Ciuti M, Mian M, Gironi A, Anichini R,

Seghieri G. Plasma and platelet taurine are reduced in subjects with insulin-dependent

diabetes mellitus: effects of taurine supplementation. Am J Clin Nutr 1995; 61: 1115–1119.

Franconi F, Miceli M, Fazzini A, Seghieri G, Caputo S, DiLeo MA, Lepore D, Ghirlanda G.

Taurine and diabetes – humans and experimental models. Adv Exp Med Biol 1996;403: 579–

582.

Freedman D, Dandona P, Fernando O, Moorhead JF. Glycosylated haemoglobin in chronic

renal failure and after renal transplantation. J Clin Pathol 1982;35:737-739.

Freeman BD. Biological sites and mechanisms of free radical production. In: Free Radicals in

Molecular Biology, Aging, and Disease, edited by Armtrong D, Sohal RS, Cutler RG and

Slater TF. New York: Raven, 1984, p 43-52.

Frei B, Higdon JV. Antioxidant activity of tea polyphenols in vivo: evidence from animal

studies. J Nute 2003;133:6190-6195.

Fridovich I. Superoxide dismutases. Annu Rev Biochem 1975;44:147-159.

Fridovich I. The biology of oxygen radicals. Science 1978;201:875-880.

Friedman JE, Dohm GL, Elton CW, Rovira A, Chen JJ, Leggett-Frazier N, Atkinson SM Jr,

Thomas FT, Long SD, Caro JF. Muscle insulin resistance in uremic humans: glucose

transport, glucose transporters, and insulin receptors. Am J Physiol 1991;261:E87-94.

Fujita K, Nishizawa H, Funahashi T, Shimomura I, Shimabukuro M. Systemic oxidative

stress is associated with visceral fat accumulation and the metabolic syndrome. Circ J

2006;70:1437–1442.

Fujishiro M, Gotoh Y, Katagiri H, Sakoda H, Ogihara T, Anai M, Onishi Y, Ono H, Abe M,

Shojima N, Fukushima Y, Kikuchi M, Oka Y, Asano T. Three mitogen-activated protein

kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol

Endocrinol 2003;17:487–497.

Fulop T, Larbi A, Douziech N. Insulin receptor and ageing. Pathol Biol 2003;51:574-80.

Furth AJ. Glycated proteins in diabetes. Br J Biomed Sci 1997;54:192–200.

Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O,

Makishima M, Matsuda M, Shimomura I. Increased oxidative stress in obesity and its impact

on metabolic syndrome. J Clin Invest. 2004;114:1752-61.

Page 16: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

269

G Galle J, Heinloth A, Schwedler S Wanner C. Effect of HDL and atherogenic Hpoproteins on

formation of O2'- and renin release in juxtaglomerular cells. Kidney Int 1997; 51:253-260.

Galle J, Schneider R, Winner B Lehmann-Bodem C, Schinzel R, Munch G, Conzelmann E,

Wanner. Glyc-oxidized LDL impair endothelial fiinction more potently than oxidized LDL:

Role of enhanced oxidative stress. Atherosclerosis 1998; 138:65-77.

Galle J. Oxidative stress in chronic renal failure. Nephrol Dial Transplant 2001;16:2135-

2137.

Garg AX, Blake PG, Clark WF, Clase CM, Haynes RB, Moist LM. Association between

renal insufficiency and malnutrition in older adults: Results from the NHANES III. Kidney

Int 2001;60:1867–1874.

Gallardo JM, de Carmen Prado-Uribe M, Amato D, Paniagua R. Inflammation and oxidative

stress markers by pentoxifylline treatment in rats with chronic renal failure and high sodium

intake. Arch Med Res 2007;38:34-8.

Gao Z, Hwang D, Bataille F, Lefevre M, York D, Quon MJ, Ye J. Serine phosphorylation of

insulin receptor substrate 1 by inhibitor kappa B kinase complex. J Biol Chem

2002;277:48115–48121.

Gao Z, Zhang X, Zuberi A, Hwang D, Quon MJ, Lefevre M, Ye J. Inhibition of insulin

sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1

adipocytes. Mol Endocrinol. 2004;18:2024-34.

Gao Z, Zuberi A, Quon MJ, Dong Z, Ye J. Aspirin inhibits serine phosphorylation of insulin

receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine

kinases. J Biol Chem 2003;278:24944–24950.

Garibotto G, Sofia A, Procopio V, Villaggio B, Tarroni A, Di Martino M, Cappelli V,

Gandolfo MT, Aloisi F, De Cian F, Sala MR, Verzola D. Peripheral tissue release of

interleukin-6 in patients with chronic kidney diseases: effects of end-stage renal disease and

microinflammatory state. Kidney Int 2006;70:384-390.

Gerard C, Bruyns C, Marchant A, Abramowicz D, Vandenabeele P, Delvaux A, Fiers W,

Goldman M, Velu T. Interleukin-10 reduces the release of tumor necrosis factor and prevents

lethality in experimental endotoxemia. J Exp Med 1993;177:547–550.

Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved

mediators of immune responses. Annu Rev Immunol 1998;16:225–260.

Page 17: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

270

Granberry MC, Fonseca VA. Insulin resistance syndrome: options for treatment. South Med J

1999;92:2–15.

Granger DN, Rutili G, McCord JM. Superoxide radicals in feline intestinal ischemia.

Gasteroenterology 81; 22-29: 1981.

Goldberg A, Hagberg J, Delmez J, Haynes ME, Harter HR. The metabolic effects of exercise

training in hemodialysis patients. Kidney Int 1989;18:754-761.

Goldstein BJ. Protein-tyrosine phosphatases: emerging targets for therapeutical intervention

in type 2 diabetes and related states of insulin resistance. J Clin Endocrinol Metab

2002;87:2474-2480.

Gomes A, Vedasiromone JR, Das M, Sharma RM, Ganguly DK. Antihyperglycemic effect of

black tea in rat. J Enthanopharmacol 1994;45:223-226.

Goodman HO, Shihabi ZK. Supplemental taurine in diabetic rats: effects on plasma glucose

and triglycerides. Biochem Med Metab Biol 1990; 43: 1–9.

Green TR, Fellman JH, Eicher AL, Pratt KL. Antioxidant role and subcellular location of

hypotaurine and taurine in human neutrophils. Biochim Biophys Acta 1991;1073:91-97.

Griesmacher A, Kindhauser M, Andert SE, Schreiner W, Toma C, Knoebl P, Prager R,

Schnack C, Schernthaner G. Enhanced serum levels of thiobarbituric acid reactive substances

in diabetes mellitus. Am J Med 1995; 98:469–475.

Griselli M, Herbert J, Hutchinson WL, Taylor KM, Sohail M, Krausz T, Pepys MB. C-

reactive protein and complement are important mediators of tissue damage in acute

myocardial infarction. J Exp Med 1999;190:1733–1740.

Guo Q, Zhao B, Li M, Sthen S, Xin W. Studies on protective mechanisms of four

components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochem

Biophys Acta 1996;1304:210-222.

H

Haber CA, Lam TK, Yu Z, Gupta N, Goh T, Bogdanovic E, Giacca A, Fantus IG. N-

acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible

role of oxidative stress. Am J Physiol Endocrinol Metab 2003;285:E744-53.

Haber F, Weiss JJ. The catalytic decomposition of hydrogen peroxide by iron salts. Proc R

Soc London 1934;A147:332–351.

Page 18: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

271

Hagar HH, Etter EE, Arafa M. Taurine attenuates hypertension and renal dysfunction induced

by cyclosporine A in rats. Clin Exper Pharm Physiol 2006;33:189-196.

Hainque B. Adipose tissue IL-6 content correlates with resistance to insulin activation of

glucose uptake both in vivo and in vitro. J Clin Endocrinol Metab 2002;87:2084–2089.

Haley RJ, Ward DM. Nonenzymatically glucosylated serum proteins in patients with end-

stage renal failure. Am J Kidney Dis 1986;8: 115-121.

Halliwell B, Gutteridge JMC. Oxygen toxicity, oxygen radicals, transition metals and disease.

Biochem J 1984;219:1–14.

Halliwell B, Gutteridge JMC. The antioxidants of human extracellular fluids. Arch Biochem

Biophys 1990;289:1-8.

Han JS, Kim YS, Chin HJ, Joen US, Ahn C, Kim S, et al. Temporal changes and reversibility

of carbamylated hemoglobin in uremia. Nephrol Dial Transplant 1989;4:96-100.

Handelman GJ, Walter MF, Adhikarla R, Gross J, Dallal GE, Levin NW, Blumberg JB.

Elevated plasma F2-isoprostanes in patients on long-term hemodialysis. Kidney Int

2001;51:1960–1966.

Hansen LL, Ikeda Y, Olsen GS, Busch AK, Mosthaf L. Insulin signaling is inhibited by

micromolar concentrations of H2O2. Evidence for a role of H2O2 in tumor necrosis factor

alpha-mediated insulin resistance. J Biol Chem 1999;274:25078–25084.

Harber F, Weiss JJ. The catalytic decomposition of hydrogen peroxide by iron salts. Proc R

Soc Lond Ser A 1981;147: 332-351.

Harding JJ. Post-translational modification of lens proteins in cataract. Lens Eye Tox Res

1991;8:245-250.

Haring HU. The insulin receptor: signalling mechanism and contribution to the pathogenesis

of insulin resistance. Diabetologia 1991;34:848-861.

Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol

1956;11:298–300.

Harris TB, Ferrucci L, Tracy RP, Corti MC, Wacholder S, Ettinger WH Jr, Heimovitz H,

Cohen HJ, Wallace R. Association of elevated interleukin-6 and C-reactive protein levels

with mortality in the elderly. Am J Med 1999;106:506–512.

Hasselwander O, Young IS: Oxidative stress in chronic renal failure. Free Radic Res

1998;29:1-11.

Haugen E, Nath KA. The involvement of oxidative stress in the progression of renal injury.

Blood Purif 1999;17:58-65.

Page 19: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

272

Hayes GR, Lockwood DH. Role of insulin receptor phosphorylation in the insulinomimetic

effects of hydrogen peroxide. Proc Natl Acad Sci U S A. 1987;84:8115–8119.

Heaton A, Taylor R, Johnston DG, Ward MK, Wilkinson R, Alberti KGGM. Hepatic and

peripheral insulin action in chronic renal failure before and during continuous ambulatory

peritoneal dialysis. Clin Sci 1989;77:383-388.

Heffetz D, Bushkin I, Dror R, Zick Y. The insulinomimetic agents H2O2 and vanadate

stimulate protein tyrosine phosphorylation in intact cells. J Biol Chem. 1990;265:2896–2902.

Heliovaara MK, Teppo AM, Karonen SL, Tuominen JA, Ebeling P. Plasma IL-6

concentration is inversely related to insulin sensitivity, and acutephase proteins associate with

glucose and lipid metabolism in healthy subjects. Diabetes Obes Metab 2005;7:729–736.

Hession C, Decker JM, Sherblom AP, Kumar S, Yue CC, Mattaliano RJ, Tizard R,

Kawashima E, Schmeissner U, Heletky S. Uromodulin (Tamm-Horsfall glycoprotein): A

renal ligand for lymphokines. Science 1987;237:1479–1484.

Himmelfarb J, McMonagle E, McMenamin E. Plasma protein thiol oxidation and carbonyl

formation in chronic renal failure. Kidney Int 2000;58:2571– 8.

Himmelfarb J, Stenvinkel P, Ikizler A, Stenvinkel P. The elephant of uremia: oxidative stress

as a unifying concept of cardiovascular disease in uremia. Kidney Int 2002;62:1524-38.

Himmelfarb J, Hakim RM. Oxidative stress in uremia. Curr Opin Nephrol Hypertens

2003;12:593-598.

Hirosumi J, Tuncman G, Chang L, Gorzun CZ, Uysal KT, Maeda K, Karin M, Hotamisligil

GS. A central role of JNK in obesity and insulin resistance. Nature 2002;420:333-336.

Ho FM, Liu SH, Liau CS, Huang PJ, Lin-Shiau SY. High glucose-induced apoptosis in

human endothelial cells is mediated by sequential activations of c- JunNH(2)-terminal kinase

and caspase-3. Circulation 2001;101:2618–2624.

Holtham SB, Schutz F. The effect of cyanate on the stability of proteins. Biochem Biophys

Acta 1949;3:65-81.

Horkko S, Savolainen MJ, Kervinen K, Kesaniemi YA. Carbamylation-induced alterations in

low-density lipoprotein metabolism. Kidney Int 1992;41:1175-1181.

Hostetter TH. Prevention of the development and progression of renal disease J AM Soc

Nephrol 2003;14:S144-S147.

Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM. Tumor necrosis factor alpha

inhibits signalling from the insulin receptor. Proc Natl Acad Sci USA 1994;91:4854–4858.

Page 20: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

273

Hotamisligil GS, Arner P, Caroj F, Atkinson RL, Spiegelman BM. Increased adipose tissue

expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin

Invest 1995;95:2409–2415.

Houstis N, Rosen ED, Lander ES. Reactive oxygen species have a causal role in multiple

forms of insulin resistance. Nature 2006;440:944–948.

Howard M, Muchamuel T, Andrade S, Menon S. Interleukin 10 protects mice from lethal

endotoxemia. J Exp Med 1993;177:1205–1208.

Hu ML, Louie S, Motchik P, Halliwell B. Antioxidant protection against hypochlorous acid

in human plasma. J Lab Clin Med 1993; 121: 257–262.

Huber SA, Sakkinen P, Conzed D, Hardin N, Tracy R. Interleukin-6 exacerbates early

atherosclerosis in mice. Arterioscler Thromb Vasc Biol 1999;19:2364–2367.

Huang Y, Domann FE. Redox modulation of AP-2 DNA binding activity in vitro. Biochem

Biophys Res Commun 1998;249, 307–312.

Hundal RS, Mayerson AB, Petersen KF, Rife FS, Randhawa PS, Inzucchi SE, Shoelson SE,

Shulman GI. Potential for a novel class of insulin sensitizing agents by inhibition of IKKβ

activity (Abstract). Diabetes 2001;A117.

Hunsicker LG, Adler S, Caggiula A, England BK, Greene T, Kusek W, Rogers NL, Teschan

PE. Predictors of the progression of renal disease in the modification of diet in renal disease

study. Kidney Int 1997;51:1908-1919.

I

Iiyama K, Hajra L, Iiyama M, Li H, DiChiara M, Medoff BD, Cybulsky MI. Patterns of

vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit

and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ Res

1999;85:199–207.

Ikizler TA, Morrow JD, Roberts LJ, Evanson JA, Becker B, Hakim RM, Shyr Y, Himmelfarb

J. Plasma F2-isoprostane levels are elevated in chronic hemodialysis patients. Clin Nephrol

2002;58:190–197.

Imbert V, Rupec RA, Livolsi A, Pahl HL, Traenckner EB, Mueller-Dieckmann C, Farahifar

D, Rossi B, Auberger P, Baeuerle PA, Peyron JF. Tyrosine phosphorylation of I kappa B-

alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. Cell

1999;86:787–798.

Page 21: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

274

Inaba M, Okuno S, Kumeda Y, Yamada S, Imanishi Y, Tabata T, Okamura M, Okada S,

Yamakawa T, Ishimura E, Nishizawa Y; Osaka CKD Expert Research Group. Glycated

albumin is a better indicator than glycated hemoglobin values in hemodialysis patients with

diabetes: effect of anemia and erythropoietin injection. J Am Soc Nephrol 2007;18:896-903.

Inal M, Kanbak G, Sen S, Akyuz F, Sunal E. Antioxidant status and lipid peroxidation in

hemodialysis patients undergoing erythropoietin and erythropoietin-vitamin E combined

therapy. Free Radic Res 1999;31:211– 216.

Inouye M, Hashimoto H, Mio T, Sumino K. Levels of lipid peroxidation product and

glycated hemoglobin A1C in the erythrocytes of diabetic patients. Clin Chim Acta

1998;276:163-172.

Inouya M, Mio T, Sumino K. Glycated hemoglobin and lipid peroxidation in erythrocytes of

diabetic patients. Metabolism 1999;48:205-209.

Inzucchi SE, Maggs DG, Spollett GR, Page SL, Rife FS, Walton V, Shulman GI. Efficacy

and metabolic effects of metformin and troglitazone in type II diabetes mellitus. N Engl J

Med 1998;338:867–872.

J Jacob S, Lehmann R, Rett K, Haring H-U: Oxidative stress and insulin action: a role for

antioxidants. In Antioxidants in Diabetes Management. Packer L, Ro¨ sen P, Tritschler HJ,

King GL, Eds. New York, Marcel Dekker, 2000, p. 319–338 .

Jacobson HR. Chronic renal failure; pathophysiology. Lancet 1991;338:419-423.

Jager J, Gremeaux T, Cormont M, et al. Interleukin-1beta induced insulin resistance in

adipocytes through down-regulation of insulin receptor substrate-1 expression.

Endocrinology 2007;148:241-251.

Jain SK. Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in

human red blood cells. J Biol Chem 1989;264:21340– 5.

Jain SK. The effect of oxygen radicals, metabolites and vitamin E on glycation of proteins in

red blood cells. Diabetes 1993;42:105A.

Jain SK, McVie R. Effect of glycemic control, race (white vs. black), and duration of diabetes

on reduced glutathione content in erythrocytes of diabetic patients. Metabolism 1994;43:306-

309.

Jain SK. Glutathione and glucose-6-phosphate dehydrogenase deficiency can increase protein

glycosylation. Free Radic Biol Med 1998;24:197–201.

Page 22: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

275

Jain SK, Lim G. Lipoic acid decreases lipid peroxidation and protein glycosylation and

incareses (Na++ K+) and Ca++-ATPase activities in high glucose-treated human erythrocytes.

Free Radic Biol Med 2000;29:1122-1128.

Jain SK, Rains J, Jones K. Effect of Curcumin on protein glycosylation, lipid peroxidation,

and oxygen radical generation in human red blood cells exposed to high glucose levels. Free

Radic Biol Med 2006;41:92-96.

Jakus V, Hrnciarova M, Carsky J, Krahulec B, Rietbrock N. Inhibition of nonenzymatic

protein glycation and lipid peroxidation by drugs with antioxidant activity. Life Sci

1999;65:1991-1993.

Jensen M, Nathan DG, Bunn HF. The reaction of cyanate with the a and b subunits in

hemoglobin. J Biol Chem 1973;248:8057-8063.

Jocelyn PC. Spectrophotometric assay of thiols. Methods in Ezymol 1987; 143: 44-67.

Johansson M, M, Elam M, Rundqvist B, Eisenhofer G, Herlitz H, Lambert G, Friberg P.

Increased sympathetic nerve activity in renovascular hypertension. Circulation 1999;99:2537-

2542.

Jones SA, Horiuchi S, Topley N, Le Marchand-Brustel Y, Tanti JF. The soluble interleukin 6

receptor: Mechanisms of production and implications in disease. FASEB J 2001;15:43–58.

John WG. Glycated haemoglobin analysis. Ann Clin Biochem 1997;34:17– 31.

Johnstoone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, Creager MA. Impaired

endothelium -dependent vasodilation in patients with insulin-dependent diabetes mellitus.

Circulation 1993;88:2510-2516.

Joy MS, Cefalu WT, Hogan SL, Nachman PH. Long-term glycemic control measurements in

diabetic patients receiving hemodialysis. Am J Kidney Dis 2002;39:297-307.

K

Kaaja RJ, Greer IA. Manifestations of chronic disease during pregnancy. JAMA

2005;294:2751-2757.

Kadota S, Fantus IG, Deragon G, Guyda HJ, Posner BI. Stimulation of insulin-like growth

factor II receptor binding and insulin receptor kinase activity in rat adipocytes. J Biol Chem.

1987;262:8252–8256.

Kahn CR. Insulin action, diabetogenes, and the cause of type 2 diabetes. Diabetes

1994;43:1066–1084.

Page 23: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

276

Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest 2000;106:473-481.

Kalantarinia K, Awad AS, Siragy HM. Urinary and renal interstitial concentrations of TNF-

alpha increase prior to the rise in albuminuria in diabetic rats. Kidney Int 2003;64:1208–

1213.

Kalantar-Zadeh K, Balakrishnan VS. The kidney disease wasting: inflammation, oxidative

stress, and diet-gene interaction. Hemodial Int 2006;10:315-325.

Kallner AB, Hartmann D, Hornig DH. On the requirements of ascorbic acid in man: steady-

state turnover and body pool in smokers. Am J of Clin Nutr 1981; 34: 1347-1355.

Kaneto H, Nakatani Y, Kawamori D, Miyatsuka T, Matsuoka TA, Matsuhisa M, Yamasaki

Y. Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in

pancreatic beta-cell dysfunction and insulin resistance. Int J Biochem Cell Biol 2006;38:782-

793.

Karin M. The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation. J Biol

Chem 1999;274:27339–27342.

Karin M, Delhase M. The I kappa B kinase (IKK) and NF-kappa B: key elements of

proinflammatory signaling. Semin Immunol 2000;12:85–98.

Karin M, Takahashi T, Kapahi P, Delhase M, Chen Y, Makris C, Rothwarf D, Baud V, Natoli

G, Guido F, Li N. Oxidative stress and gene expression: the AP-1 and NFkappa B

connections. Biofactors 2001;15:87–89.

Karin M, Ben-Neriah Y. Regulatory functions of ubiquitination in the immune system. Nat

Immunol 2002;3:20–26

Karin M, Lin A. NF-kappaB at the crossroads of life and death. Nat Immunol 2002;3:221–

227.

Karkar AM, Koshino Y, Cashman SJ, et al. Passive immunization against tumour necrosis

factor-alpha (TNF-alpha) and IL-1 beta protects from LPS enhancing glomerular injury in

nephrotoxic nephritis in rats. Clin Exp Immunol 1992;90:312–318.

Karkar AM, Smith J, Pusey CD. Prevention and treatment of experimental crescentic

glomerulonephritis by blocking tumour necrosis factor-alpha. Nephrol Dial Transplant

2001;16:518–524.

Kasai T, Inada K, Takakuwa T, Yamada Y, Inoue Y, Shimamura T, Taniguchi S, Sato S,

Wakabayashi G, Endo S. Anti-inflammatory cytokine levels in patients with septic shock.

Res Commun Mol Pathol Pharmacol 1997;98:34–42.

Kato Jr T, Delhase M, Hoffmann A, Karin M. CK2 Is a C-Terminal IkappaB Kinase

Responsible for NF-kappaB Activation during the UV Response. Mol Cell 2003;12:829–839.

Page 24: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

277

Kato A, Takita T, Maruyamay, Hishida A. Chlamydial infection and progression of carotid

atherosclerosis in patients on regular haemodialysis. Nephrol Dial Transplant 2004;19:2539–

2546.

Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative

insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in

humans. J Clin Endocrinol Metab 2000;85:2402–10.

Kawabata T, Packer L. Alpha-lipoate can protect against glycation of serum albumin, but not

low density lipoprotein. Biochem Biophys Res Commun 1994;203:99-104.

Keane WF. Proteinuria: its clinical importance and role in progressive renal disease. Am J

Kidney Dis 2000; 35: S97-S105.

Keren P, Rina H, Derek L. Molecular basis of insulin resistance: Elevated Serine/Threonine

phosphorylation of IRS-1 and IRS-2 inhibits their binding to the jextamembrane region of the

insulin receptor and impairs their ability to undergo insulin induced tyrosine phosphoryla-

tion. J Biol Chem 1997;272, 29911-29918.

Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis

factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol

2001;280:E745–E751.

Khan SG, Kattiyar SK, Agarwal R, Mukhtar H. Enhancement of antioxidant and phase II

enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice

possible role in cancer chemoprvention. Cancer Res 1992;52:4050-4052.

Kher V. End-stage renal disease in developing countries. Kidney Int 2002; 62: 350–62.

Kietzmann T, Fandrey J, Acker H. Oxygen radicals as messengers in oxygen-dependent gene

expression. News Physiol Sci. 2000;15:202–208.

Kim JK, Kim YJ, Fillmore JJ, Chen Y, Moore I, Lee J, Yuan M, Li ZW, Karin M, Perret P,

Shoelson SE, Shulman GI. Prevention of fat-induced insulin resistance by salicylate. J Clin

Invest 2001;108:437-446.

Kim HJ, Higashimori T, Park SY, Choi H, Dong J, Kim YJ, Noh HL, Cho YR, Cline G, Kim

YB, Kim JK. Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin

action in vivo. Diabetes 2004;53:1060–1067.

Kim HJ, Hawke N, Baldwin AS. NF-kappa B and IKK as therapeutic targets in cancer. Cell

Death Differ 2006;13:738-747.

Kimmel PL, Phillips TM, Simmens SJ, Peterson RA, Weihs KL, Alleyne S, Cruz I, Yanovski

JA, Veis JH. Immunologic function and survival in hemodialysis patients. Kidney Int

1998;54:236–244.

Page 25: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

278

Kislinger T, Tanji N, Wendt T, Qu W, Lu Y, Ferran LJ Jr, Taguchi A, Olson K, Bucciarelli

L, Goova M, Hofmann MA, Cataldegirmen G, D'Agati V, Pischetsrieder M, Stern DM,

Schmidt AM.Receptor for advanced glycation end products mediates inflammation and

enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.

Arteriosclerosis Thromb Vasc Biol 2001;21:905-910.

Kitiyakara C, Gonin J, Massy Z, Wilcox CS. Non-traditional cardiovascular disease risk

factors in end-stage renal disease: oxidative stress and hyperhomocysteinemia. Curr oin

Nephrol Hypertens 2000;9:477-487.

Klover PJ, Zimmers TA, Koniaris LG, Mooney RA. Chronic exposure to interleukin-6

causes hepatic insulin resistance in mice. Diabetes 2003;52:2784–2789.

Klemm A, Voigt C, Friedrich M, Fünfstück R, Sperschneider H, Jäger EG, Stein G.

Determination of erythrocyte antioxidant capacity in haemodialysis patients using electron

paramagnetic resonance. Nephrol Dial Transplant 2001;16:2166-71.

Knight JA. Biochmeistry of aging. Adv Clin Chem 2000;35:1-62.

Kobayashi S, Maesato K, Moriya H, Ohtake T, Ikeda T. Insulin resistance in patients with

chronic kidney disease. Am J Kidney Dis 2005;45:275-280.

Kolterman OG, Insel J, Saekow M, Olefsky JM. Mechanisms of insulin resistance in human

obesity: evidence for receptor and post-receptor defects. J Clin Invest 1980;65:1272-1284.

Koner BC, Banerjee BD, Ray A. Effects of in vitro generation of oxygen free radicals on

immune responsiveness in rabbits. Immunol Lett 1997;59:127-31.

Korish AA, Arafah MM. Catechin combined with vitamins C and E ameliorates insulin

resistance (IR) and atherosclerotic changes in aged rats with chronic renal failure (CRF).

Arch Gerontol Geriatr. 2008;46:25-39.

Koshio O, Akanuma Y, Kasuga M. Hydrogen peroxide stimulates tyrosine phosphorylation

of the insulin receptor and its tyrosine kinase activity in intact cells. Biochem J. 1988;250:95–

101.

Kosmidou I, Vassilakopoulos T, Xagorari A, Zakynthinos S, Papapetropoulos A, Roussos C.

Production of interleukin-6 by skeletal myotubes: Role of reactive oxygen species. Am J

Respir Cell Mol Biol 2002;26:587–593.

Kovarik J, Stummvoll HK, Graf H, Muller MM. Glucose intolerance and hemoglobin A1 in

chronic renal insufficiency. Nephron 1981;28:209-212.

Krieger-Brauer HI, Kather H. Human fat cells possess a plasma membrane-bound H2O2

generating system that is activated by insulin via a mechanism bypassing the receptor kinase.

J Clin Invest 1992;89:1006–1013.

Page 26: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

279

Kulakowski EC, Maturo J. Hypoglycemic properties of taurine: not mediated by enhanced

insulin release. Biochem Pharmacol 1984; 33: 2835–2838.

Kumar A, Lnu S, Malya R, Barron D, Moore J, Corry DB, Boriek AM. Mechanical stretch

activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in

lung parenchyma: implications in asthma. FASEB J 2003;17:1800–1811.

Kumar A, Takada Y, Boriek AM, Aggarwal BB. Nuclear factor-kB: its role in health and

disease. J Mol Med 2004; 82:434–448.

Kunsch C, Medford RM. Oxidative stress as a regulator of gene expression in the

vasculature. Circ Res 1999;85:753–66.

L

Lagrand WK, Visser CA, Hermens WT , Niessen HW, Verheugt FW, Wolbink GJ, Hack CE.

C-reactive-protein as a cardiovascular risk: more than an epiphenomenon? Circulation

1999;100:96–102.

Lahera V, Goicoechea M, De Vinuesa SG, Oubi a P, Cachofeiro V, Gomez-Campdera F,

Amann R, Luno J. Oxidative stress in uremia: The role of anemia correction. J Am Soc

Nephrol 2006;17:S174-S177.

Lamb RE, Goldstein BJ. Modulating an oxidative-inflammatory cascade: potential new

treatment strategy for improving glucose metabolism, insulin resistance, and vascular

function. Int J Clin Pract 2008;62:1087–1095.

Lampson WG, Kramer JH, Schaffer SW. Potentiation of the actions of insulin by taurine. Can

J Physiol Pharmacol 1983; 61: 457–463.

Landray MJ, Wheeler DC, Lip GY, Newman DJ, Blann AD, McGlynn FJ, Ball S, Townend

JN, Baigent C. Inflammation, endothelial dysfunction, and platelet activation in patients with

chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study. Am J

Kidney Dis 2004;43:244–253.

Lapolla A, Fedele D, Plebani M, Aronica R, Garbeglio M, Seraglia R, D'Alpaos M, Traldi P.

Evaluation of glycated globins by matrix-assisted laser desorption/ionization mass

spectrometry. Clin Chem 1999;4:288– 90.

Lapolla A, Traldi P, Fedele D. Importance of measuring products of non-enzymatic glycation

of proteins. Clin Biochem 2005;38:103-115.

Page 27: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

280

Larriviere F, Chiasson JL, Schiffrin A, Taveroff A, Hoffer LJ. Effects of dietary protein

restriction on glucose and insulin metabolism in normal and diabetic humans. Metabolism

1994;43:462-467.

Larsen ML. The clinical usefulness of glycated haemoglobin in diabetes care evaluated by

use of a medical technology assessment strategy. Dan Med Bull 1997;303– 15.

Lawrence T, Gilroy DW, Colville-Nash PR, Willoughby DA. Possible new role for NF-

kappaB in the resolution of inflammation. Nat Med 2001;7:1291–1297.

Lawrence JC Jr, Roach PJ. New insights into the role and mechanism of glycogen synthase

activation by insulin. Diabetes 1997;46:541-547.

Le Hir M, Haas C, Marino M, Ryffel B. Prevention of crescentic glomerulonephritis induced

by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice. Lab Invest

1998;78:1625–1631.

Lee JA, Lee HR, Sadler PJ. Uraemia: is urea more important than we think? Lancet

1991;38:1438-1440.

Lee JC, Kumar S, Griswold DE, Underwood DC, Votta BJ, Adams JL. Inhibition of p38

MAP kinase as a therapeutic strategy. Immunopharmacology 2000; 47: 185–201.

Lee FS, Peters RT, Dang LC, Maniatis T. MEKK1 activates both IkappaB kinase alpha and

IkappaB kinase beta. Proc Natl Acad Sci USA 1998;95:9319–9324.

Lee HS, Song CY.Oxidized Low-Density Lipoprotein and Oxidative Stress in the

Development of Glomerulosclerosis. Am J Nephrol. 2008;29:62-70.

Lee SR, Yang KS, Kwon J, Lee C, Jeong W, Rhee SG. Reversible inactivation of the tumor

suppressor PTEN by H2O2. J Biol Chem 2002;277:20336–20342.

LeRoith D, Zick Y. Recent advances in our understanding of insulin action and insulin

resistance. Diabetes Care 2001;24:588-597.

Leung HW, Vang MJ, Mavis RD. The cooperative interaction between vitamin E and vitamin

C in suppression of peroxidation of membrane phospholipids. Biochim Biophys Acta 1973;

664: 266-272.

Levine B, Kalman J, Mayer L, Fillit HM, Packer M. Elevated circulating levels of tumor

necrosis factor in severe chronic heart failure. N Engl J Med 1990;323:236–241.

Lewis TS, Shapiro PS, Ahn NG, 1998. Signal transduction through MAP kinase cascades. In:

Woude GFV, Klein G, eds. Advances in cancer research. San Diego: Academic Press Inc.;

vol 74, 49–139.

Page 28: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

281

Li X, Chen H, Epstein PN. Metallothionein and catalase sensitize to diabetes in nonobese

diabetic mice. Reactive oxygen species may have a protective role in pancreatic β-cells.

Diabetes 2006;55:1592-604.

Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, Scherer PE. The

hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen

species. J Biol Chem 2005;280:4617–4626.

Li N, Karin M. Is NF-kappaB the sensor of oxidative stress? FASEB J 1999;13:1137-1143.

Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat Rev Immunol

2002;2:725-734.

Ligier S, Fortin PR, Newkirk MM.A new antibody in rheumatoid arthritis targeting glycated

IgG: IgM anti-IgG-AGE. Br J Rheumatol. 1998;37:1307-14.

Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B,

Lindsay RM, Smith W, Lee WK, Dominiczak MH, Baird JD. The effect of δ-gluconolactone,

an oxidized analogue of glucose, on the nonenzymatic glycation of human and rat

hemoglobin. Clin Chim Acta 1997;263:239–47.

Ling L, Cao Z, Goeddel DV. NF-kappaB-inducing kinase activates IKK-alpha by

phosphorylation of Ser-176. Proc Natl Acad Sci USA 1998;95:3792–3797.

Locatelli F, Amico MD, Cernevskis H, Dainys B, Miglinas M, Luman M, Ots M, Ritz E. The

epidemiology of end-stage renal disease in the Baltic countries: an evolving picture. Nephrol

Dial Transplant 2001;16: 1338-42.

Locatelli F, Canaud B, Eckardt KU, Stenvinkel P, Wanner C, Zoccali C. Oxidative stress in

end-stage renal disease: an emerging threat to patient outcome. Nephrol Dial Transplant

2003;18:1272-1280.

London GM, Parfrey PS. Cardiac disease in chronic uremia: pathogenesis. Adv Ren Replace

Ther 1997;4:194-211.

Lu D, Maulik N, Moraru II, Kreutzer DL, Das DK. Molecular adaptation of vascular

endothelial cells to oxidative stress. Am J Physiol 1993;264:C715–C722.

Lundgren M, Svensson M, Lindmark S, Renstrom F, Ruge T, Eriksson JW. Fat cell

enlargement is an independent marker of insulin resistance and ‘hyperleptinaemia’.

Diabetologia 2007;50:625–633.

Lyons TJ. Glycation, oxidation and glycoxidation reactions in the development of diabetic

complications. Contrib Nephrol 1995;112:1– 10.

Page 29: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

282

M

Macallum AB, Sivertz C. The potentiation of insulin by sulfones. Can Chem Process Ind

1942; 26: 569.

MacMillan-Crow LA, Crow JP, Kerby JD, Beckman JS, Thompson JA. Nitration and

inactivation of manganese superoxide dismutase in chronic rejection of human renal

allografts. Proc Natl Acad Sci USA 1996;93:11853–11858.

Maddux BA, See W, Lawrence JC Jr, Goldfine AL, Goldfine ID, Evans JL: Protection

against oxidative stress-induced insulin resistance in rat L6 muscle cells by micromolar

concentrations of α-lipoic acid. Diabetes 2001;50:404–410.

Madrid LV, Mayo MW, Reuther JY, Baldwin AS Jr. Akt stimulates the transactivation

potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase

and activation of the mitogen-activated protein kinase p38. J Biol Chem 2001;276:18934-40.

Majer M, Popov KM, Harris RA, Bogardus C, Prochazka M. Insulin down regulates pyruvate

dehydrogenase kinase (PDK) mRNA: potential mechanism contributing to increased lipid

oxidation in insulin-resistant subjects. Mol Genet Metab 1998;65:181-186.

Mak RHK, Turner C, Thompson T, Haycock GB, Chantler C. The effects of low protein diet

with amino acid/keto acid supplements on glucose metabolism in children with uremia. J Clin

Endocrinol Metab 1986;63:985.

Mak RHK. Carbohydrate metabolism in uremia. Pediatr Nephrol 1989;3:201-208.

Mak RHK. Effect of recombinant human erythropoietin on insulin, amino acid, and lipid

metabolism in uremia. J Pediatr 1996;129:97-104.

Marchant A, Deviere J, Byl B, De Groote D, Vincent JL, Goldman M. Interleukin-10

production during septicaemia. Lancet 1994;343:707–708.

Maritim AC, Sanders RA, Watkins JB 3rd. Effects of alpha-lipoic acid on biomarkers of

oxidative stress in streptozotocin-induced diabetic rats. J Nutr Biochem 2003;14:288-294.

Marty C, Misset B, Tamion F, Fitting C, Carlet J, Cavaillon JM. Circulating interleukin-8

concentrations in patients with multiple organ failure of septic and nonseptic origin. Crit Care

Med 1994;22:673–679.

Mates JM, Perez-Gomez C, Nunez de Castro I. Antioxidant enzymes and human diseases.

Clin Biochem 1999;32:595– 603.

Page 30: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

283

Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis

model assessment: insulin resistance and beta-cell function from fasting plasma glucose and

insulin concentrations in man. Diabetologia 1985;28:412–9.

Mayer TK, Freedman ZR. Protein glycosylation in diabetes mellitus: a review of laboratory

measurements and of their clinical utility. Clin Chim Acta 1983;127:147–84.

Mayerson AB, Hundal RS, Dufour S, Lebon V, Befroy D, Cline GW, Enocksson S, Inzucchi

SE, Shulman GI, Petersen KF: The effects of rosiglitazone on insulin sensitivity, lipolysis,

and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes

2002;51:797–802.

McCarty MF. Exploiting complementary therapeutic strategies for the treatment of type II

diabetes and prevention of its complications. Med Hypotheses 1997; 49: 143–152.

McCarthy ET, Sharma R, Sharma M, Li JZ, Ge XL, Dileepan KN, Savin VJ. TNF-alpha

increases albumin permeability of isolated rat glomeruli through the generation of

superoxide. J Am Soc Nephrol 1998;9:433–438.

McClung JP, Roneker CA, Mu W, Lisk DJ, Langlais P, Liu F, Lei XG.et al: Development of

insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase. Proc

Natl Acad Sci USA 2004;101:8852-8857.

McCord JM, Fridovich I. the utility of superoxide dismutase in studing free radicals. II. The

mechanism of the mediation of cytochrome c reduction by a variety of electron carriers. J.

Biol.Chem 262; 1374-1377: 1970.

McIntyre EA,WalkerM. Genetics of type 2 diabetes and insulin resistance: knowledge from

human studies. Clin Endocrinol (Oxf) 2002;57:303–11.

Mckay DL, Blumberg JB. The role of tea in human health: An update. Journal of the

American College of Nutrition 2002;21:1-13.

Mackenzie HS, Brenner BM. Current strategies for retarding progression of renal disease.

Am J Kidney Dis 1998;31:161-170.

Maritim AA, Sanders RA, Watkins JB III. Diabetes, oxidative stress, and antioxidants: a

review. J Biochem Mol Toxicol 2003;17:24–38.

Mee-Kyuing C, Il-Han K. Glutathione-linked thiol peroxidase activity in human serum

albumin: a possible antioxidant role of serum albumin in blood plasma. Biochem Biophys

Res Commun 1996; 222: 619-625.

Michiels C, Remacle J. Cytotoxicity of linoleic acid peroxides, malondialdehyde and 4-

hydroxynonenal towards human fibroblast. Toxicology 1991;66:225–34.

Page 31: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

284

Michieles C, Toussaint O, Remacle J. Comparative study of oxygen toxicity on human

fibroblasts and endothelial cells. J Cell Physiol 1990;144:295–302.

Mimic-Oka J, Simic T, Djukanovic L, Reljic Z, Davicevic Z. Alteration in plasma antioxidant

capacity in various degrees of chronic renal failure. Clin Nephrol 1999;51(4):233– 41.

Miyata T, van Ypersele de Strihou C, Kurokawa K, Baynes JW. Alterations in nonenzymatic

biochemistry in uremia: origin and significance of ‘‘carbonyl stress’’ in long-term uremic

complications. Kidney Int 1999;55:389– 99.

Mizuno T, Matsui H, Imamura A, Numaguchi Y, Sakai K, Murohara T, Okumura K. Insulin

resistance increases circulating malondialdehyde-modified LDL and impairs endothelial

function in healthy young men. Int J Cardiol 2004;97:455–461.

Moeller S, Gioberge S, Brown G. ESRD patients in 2001: global overview of patients,

treatment modalities and development trends. Nephrol Dial Transplant 2002;17: 2071-6.

Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Yudkin JS, Klein S, Coppack

SW. Subcutaneous adipose tissue releases interleukin-6, but not tumour necrosis factor-a, in

vivo. J Clin Endocrin Metab 1997;82:4196–4200.

Mohan Kumar KM, Bobby Z, Selvaraj N, Kumar Das A, Chandra Koner B, Sen SK, Ramesh

R, Ranganathan P. Possible link between glycated hemoglobin and lipid peroxidation in

hyperthyroidism. Clin Chim Acta 2004;342:187-192.

Mohanty P, Hamouda W, Garg R, Aljada A, Ghanim H, Dandona P. Glucose challenge

stimulates reactive oxygen species generation by leucocytes. J Clin Endocrinol Metab 2000;

85: 2970–2973.

Moon H-S, Lee H-G, Choi Y-J, Kim T-G, Cho C-S. Proposed mechanisms of (-)-

epugallocatechin-3-gallate for anti-obesity. Chemico-Biological Interactions 2007;167:85-98.

Morehouse LA, Thomas CE, Aust SD. Superoxide-generation by NADPH-cytochrome P-450

reductase: the effect of iron chelators and the role of superoxide in microsomal lipid

peroxidation. Arch Biochem Biophys 232; 366-377: 1984.

Mothe I, Van Obberghen E. Phosphorylation of insulin receptor substrate- 1 on multiple

serine residues, 612, 632, 662, and 731, modulates insulin action. J Biol Chem 1996;271,

11222–11227.

McAuley KA,Williams SM, Mann JI, Walker RJ, Lewis-Barned NJ, Temple LA, Duncan

AW. Diagnosing insulin resistance in the general population. Diabetes Care 2001;24:460–4.

Mukhopadhyay A, Manna SK, Aggarwal BB. Pervanadate-induced nuclear factor-kappaB

activation requires tyrosine phosphorylation and degradation of IkappaB alpha. Comparison

with tumor necrosis factor-alpha. J Biol Chem 2000; 275:8549–8555.

Page 32: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

285

N

Nadhini ATA, Anuradha CV. Inhibition of lipid peroxidation, protein glycation and elevation

of membrane ion pump activity by taurine in RBC exposed to high glucose. Clin Chim Acta

2003;336:129-135.

Nandhini AT, Thirunavukkarsu V, Anuradha CV. Taurine modifies insulin signaling

enzymes in the fructose-fed insulin resistant rats. Diabetes Metab 2005;31:337-344.

Nakagawa T, Yokozawa T, Terasawa K, Shu S, Juneja LR. Protective activity of green tea

against free radical- and glucose-mediated protein damage. J Agric Food Chem

2002;50:2418-22.

Nakamura T, Ushiyama C, Suzuki S. Effects of taurine and vitamin E on microalbuminuria,

plasma metalloproteinase-9, and serum type IV collagen concentrations in patients with

diabetic nephropathy. Nephron 1999; 83: 361–362.

Nakanishi I, Moutabarrik A, Okada N, Takahara S, Kokado Y, Ishibashi M, Sonoda T.

Interleukin-8 in chronic renal failure and dialysis patients. Nephrol Dial Transplant

1994;9:1435–1442.

Nakao T, Matsumoto H, Okada T, Han M, Hidaka H, Yoshino M. Influence of erythropoietin

treatment on hemoglobin A1C levels in patients with chronic renal failure on hemodialysis.

Intern Med 1998;37:826-830.

Nakatani Y, Kaneto H, Kawamori D, Hatazaki M, Miyatsuka T, Matsuoka TA, Kajimoto Y,

Matsuhisa M, Yamasaki Y, Hori M. Modulation of the JNK pathway in liver affects insulin

resistance status. J Biol Chem. 2004;279:45803-9.

Nakaya Y, Minami A, Harada N, Sakamoto S, Niwa Y, Ohnaka M. Taurine improves insulin

sensitivity in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous type 2

diabetes. Am J Clin Nutr 2000;71:54-58.

Nara Y, Yamori Y, Lovenberg W. Effect of dietary taurine on blood pressure in

spontaneously hypertensive rats. Biochem Pharmacol 1978;27:2689-92.

Nath KA, Salahudeen AK. Induction of renal groth and injury in the intact rat kidney by

dietary deficiency and antioxidants. J Clin Invest 1990; 86: 1179-1192.

Page 33: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

286

Navarro JF, Mora C, Rivero A, Gallego E, Chahin J, Macía M, Méndez ML, García J.

Urinary protein excretion and serum tumor necrosis factor in diabetic patients with advanced

renal failure: Effects of pentoxifylline administration. Am J Kidney Dis 1999;33:458–463.

Navarro JF, Mora C, Maca M, Garca J. Inflammatory parameters are independently

associated with urinary albumin in type 2 diabetes mellitus. Am J Kidney Dis 2003;42:53–61.

Nguyen-Khoa T, Massy ZA, De Bandt JP, Kebede M, Salama L, Lambrey G, Witko-Sarsat

V, Drueke TB, Lacour B, Thevenin M. Oxidative stress and haemodialysis: role of

inflammation and duration of dialysis treatment. Nephrol Dial Transplant 2001;16:335–340.

Nguyen MTA, Satoh H, Favelyukis S, Babendure JL, Imamura T, Sbodio JI, Zalevsky J,

Dahiyat B, Chi N-W, Olefsky JM. JNK and tumor necrosis factor-α mediate free fatty acid-

induced insulin resistance in 3T3-L1 adipocytes. J Biol Chem 2005;280:35361-35371.

Niskanen LK, Salonen JT, Nyyssonen K, Uusitupa MI. Plasma lipid peroxidation and

hyperglycemia: a connection through hyperinsulinaemia? Diabet Med 1995; 12: 802–808.

Nawawi H, Osman NS, Annuar R, Khalid BA, Yusoff K. Soluble intercellular adhesion

molecule-1 and interleukin-6 levels reflect endothelial dysfunction in patients with primary

hypercholesterolaemia treated with atorvastatin. Atherosclerosis 2003;169:283–291.

O Obata T, Brown GE, Yaffe MB. MAP kinase pathways activated by stress: the p38 MAPK

pathway. Crit Care Med 2000;28, N67–N77.

Oberley LW. Free radicals and diabetes. Free Radic Biol Med 1998;5:113–124.

Oberg BP, McMenamin E, Lucas FL, McMonagle E, Morrow J, Ikizler TA, Himmelfarb J.

Increased prevalence of oxidant stress and inflammation in patients with moderate to severe

chronic kidney disease. Kidney Int 2004; 65:1009-1016.

Odetti P, Garibaldi S, Noberasco G, Aragro I, Valentini S, Traverso N, et al., Levels of

carbonyl groups in plasma proteins of type 2 diabetes mellitus. Acta Diabetologia

1999;36:179–183.

Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide

anion production. J Clin Invest 1993; 91:2546-2551.

Oimoni M, Kubota S, Takagi K, Kawasaki T, Tanke G, Yoshimura Y. Glycosylated

hemoglobin in renal failure. Nephron 1981;28:306.

Page 34: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

287

Oimomi M, Matsumoto S, Hatanaka H, Ishikawa K, Kubota S, Yoshimura Y. Determination

of carbamylated plasma protein and its clinical application to renal failure. Nephron

1985;40:405-406.

Okada T, Nakao T, Matsumoto H, Shino T, Nagaoka Y, Tomaru R, Wata T. Association

between markers of glycemic control, cardiovascular complications and survival in type 2

diabetic patients and endstage renal disease. Intern Med 2007;46:807-814.

Okar DA, Lange AJ. Fructose-2,6-bisphosphate and control of carbohydrate metabolism in

eukaryotes. Biofactors 1999;10:1-14.

O'Rahilly S. Insights into obesity and insulin resistance from the study of extreme human

phenotypes. Eur J Endocrinol 2002;147:435–41.

Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, Hotta K, Nishida M,

Takahashi M, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Funahashi T,

Matsuzawa Y. Adiponectin, an adipocytes-derived plasma protein, inhibits endothelial NF-

kB signalling through a cAMP-dependent pathway. Circulation 2000;102:1296-1301.

P

Packer L, Rosen P, Tritschler H, King GL, Azzi A (Eds): Antioxidants and Diabetes

Management. New York, Marcel Dekker, 2000.

Pahl HL. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene

1999;18:6853–6866.

Paisey R, Banks R, Holton R, Young K, Hopton M, White D, Hortog M. Glycosylated

hemoglobin in uremia. Diabetic Med 1986;3:445-448.

Pamplona R, Prat J, Cadenas S, Rojas C, Perez-Campo R, Lopez Torres M, Barja G. Low

fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-

lived species: the pigeon and human case. Mech Ageing Dev1996; 86:53–66.

Pan X, Niu G, Liu H. Microwave-assisted extraction of tea polyphenols and tea caffeine from

green tea leaves. Chemical Engineering and processing 2003;42:129-133.

Panichi V, Migliori M, De Pietro S, Taccola D, Andreini B, Metelli MR, Giovannini L, Palla

R. The link of biocompatibility to cytokine production. Kidney Int 2000;58:96-103.

Paolisso G, D’Amore A, DiMaro G, Galzerano D, Tesauro P, Varricchio M. Evidence for a

relationship between free radicals and insulin action in elderly. Metabolism 1993; 42: 659–

663.

Page 35: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

288

Paolisso G, Giugliano D. Oxidative stress and insulin action. Is there a relationship?

Diabetologia 1996;39:357–363.

Parija M, Bobby Z, Kumar VS, Saradha B. Oxidative stress and protein glycation in patients

with chronic obstructive pulmonary disease. Indian J Physiol Pharmacol 2005;49:95-98.

Park DS, Stefanis L, Yan CYI, Farinelli SE, Greene LA. Ordering the cell death pathway.

Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor,

and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12

cells. J Biol Chem 2001; 271, 21898–21905.

Pecoits-Filho R, Barany B, Lindholm B, Heimbürger O, Stenvinkel P. Interleukin-6 and its

receptor is an independent predictor of mortality in patients starting dialysis treatment.

Nephrol Dial Transplant 2002;17:1684–1688.

Pecoits-Filho R, Lindholm B, Stenvinkel P. The malnutrition, inflammation, and

atherosclerosis (MIA) syndrome: the heart of the matter. Nephrol Dial Transplant

2002;17:28-31.

Pecoits-Filho R, Heimbürger O, Bárány P, Suliman M, Fehrman-Ekholm I, Lindholm B,

Stenvinkel P. Associations between circulating inflammatory markers and residual renal

function in CRF patients. Am J Kidney Dis 2003;41:1212–1218.

Peraldi P, Xu M, Spiegelman BM. Thiazolidinediones block tumor necrosis factor-alpha-

induced inhibition of insulin signaling. J Clin Invest 1997;100:1863-1869.

Pessin JE, Saltiel AR. Signalling pathways in insulin action: molecular targets of insulin

resistance. J Clin Invest 2000;106:165-169.

Pianetti S, Arsura M, Romieu-Mourez R, Coffey RJ, Sonenshein GE. Her-2/neu

overexpression induces NFkappaB via a PI3-kinase/Akt pathway involving calpain-mediated

degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene

2001; 20:1287–1299.

Pickavance, L.C., Wilding, J.P., 2001. Effects of S 15511, a therapeutic metabolite of

insulin sensitizing agent S15261, in Zucker Diabetic Fatty rat. Diabetes Obes Metab 2001;9:

114-120.

Pieri C, Testa R, Marra M, Bonfigli AR, Manfrini S, Testa I. Age dependent changes of

serum oxygen radical scavenger capacity and haemoglobin glycosylation in non-insulin-

dependent diabetic patients. Gerontology 2001;47:88-92.

Pinsky MR, Vincent JL, Deviere J, Alegre M, Kahn RJ, Dupont E. Serum cytokine levels in

human septic shock: Clin J Am Soc Nephrol 2006;1:979–986.

Page 36: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

289

Pirola L, Johnston AM, Van Obberghen E. Modulation of insulin action. Diabetologia

2004;47:170–84.

Pjodkowaki RA, Grotz VL, Mudalar S, Henry RR. The effects of alpha lipoic acid on glucose

homeostasis in type 2 diabetes. J Invest Med 2002;50:71A.

Poole S, Bird TA, Selkirk S, Gaines-Das RE, Choudry Y, Stephenson SL, Kenny AJ,

Saklatvaa J. Fate of injected interleukin 1 in rats: Sequestration and degradation in the

kidney. Cytokine1990; 2:416–422.

Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6,

and risk of developing type 2 diabetes mellitus. JAMA 2001;286:327–334.

Purcell NH, Yu C, He D, Xiang J, Paran N, DiDonato JA, Yamaoka S, Shaul Y, Lin A.

Activation of NF-kappaB by hepatitis B virus X protein through an IkappaB kinase

independent mechanism. Am J Physiol Gastrointest Liver Physiol 2001;280:G669–G677.

Q

Qi C, Pekala PH. Tumor necrosis factor-alpha-induced insulin resistance in adipocytes. Proc

Soc Exp Biol Med 2000;223:128 –135.

Qiao L, Goldberg JL, Russell JC, Sun XL. Identification of enhanced serine kinase activity in

insulin resistance. J Biol Chem 1999;274:10625-10632.

R

Rahbar S. An abnormal hemoglobin in reed cells of diabetics. Clin Chim Acta 1968;22:296–

8.

Rahman I, MacNee W. Regulation of redox glutathione levels and gene transcription in lung

inflammation: therapeutic approaches. Free Radic Biol Med 2000;28:1405-20.

Rambod M, Broumand B. Glycosylated hemoglobin, glycemic control, and mortality in

hemodialzed diabetic patients. Kidney Int 2007;71:1078.

Rana SVS, Allen T, Singh R. Inevitable glutathione, then and now. Indian J Exp Biol 2002;

40: 706-716.

Raught B, Gingras AC, Sonenberg N. The target of rapamycin (TOR) proteins. Proc Natl

Acad Sci U S A 2001;98:7037–44.

Page 37: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

290

Rauchhaus M, Doehner W, Francis DP, Davos C, Kemp M, Liebenthal C, Niebauer J,

Hooper J, Volk HD, Coats AJ, Anker SD. Plasma cytokine parameters and mortality in

patients with chronic heart failure. Circulation 2000;102:3060–3067.

Reaich D, Channon SM, Scrimgeour CM, Daley SE, Wilkinson R, Goodship THJ. Correction

of acidosis in humans with CRF decreases protein degradation and amino acid oxidation. Am

J Physiol 1993;265:E230-E235.

Reaven GM. Insulin resistance and its consequences: type 2 diabetes mellitus and coronary

heart disease. In Diabetes Mellitus: A Fundamental and Clinical Text. LeRoith D, Taylor SI,

Olefsky JM, Eds. Philadelphia,Lippincott Williams & Wilkins, 2000, p. 604–615.

Reibel DK, Shaffer JE, Kocsis JJ, Neely JR. Changes in taurine content in heart and other

organs of diabetic rats. J Mol Cell Cardiol 1979; 11: 827–830.

Remuzzi G, Ruggenenti P, Benigni A. Understanding the nature of renal disease progression.

Kidney Int 1997;51:2-15.

Remuzzi G, Bemuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J

Med 1998;339:1448–1456.

Renier G. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), a relevant target

for diabetic vasculopathy? Cardiovasc Hematol Disord Drug Targets 2008;8:203-11.

Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for

carbonyl assay. Methods Enzymol 1994;233:357–63.

Richard MJ, Arnaud J, Jurkovitz C, Hachache T, Meftachi H, Laporte F, Foret M, Favier A,

Corolonnier D. Trace elements and lipid peroxidation abnormalities in patients with chronic

renal failure. Nephron 1991;57:10–15.

Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin and

the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973–9.

Ridker PM. High-sensitivity C-reactive protein: potential adjunct for global risk assessment

in the primary prevention of cardiovascular disease. Circulation 2001;103:1813–1818.

Ridker PM, Rifai N, Stampfer MJ, Hennekens. Plasma concentration of interleukin-6 and the

risk of future myocardial infarction among apparently healthy men. Circulation

2000;101:1767– 1772.

Rigalleau V, Combe C, Blanchtier V, Aubertin J, Apacicio M, Gin H. Low protein diet in

uremia: Effects of glucose metabolism and energy production rate. Kidney Int 1997;51:1222-

1227.

Roden M, Shulman GI. Applications of NMR spectroscopy to study muscle glycogen

metabolism in muscle. Annu Rev Med 1999;50:277–290.

Page 38: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

291

Rodriguez-Garcia J, Requena JR, Rodriguez-Segade R. Increased concentrations of serum

pentosidine in rheumatoid arthritis. Clin Chem 1998;44:250-255.

Romagnani S. T-cell subsets (Th1 versus Th2). Ann Allergy Asthma Immunol 2000;85:9-21.

Rosenzweig T, Braiman L, Bak A, Alt A, Kuroki T, Sampson SR. Differential effects of

tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition

of insulin receptor signaling. Diabetes 2002;51:1921–1930.

Rothwarf DM, Zandi E, Natoli G, Karin M. IKKgamma is an essential regulatory subunit of

the IkappaB kinase complex. Nature 1998;395:297–300.

Rotter V, Nagaev I, Smith U. Interleukin-6 (IL-6) induces insulin resistance in 3T3–L1

adipocytes and is, like IL-8 and tumor necrosis factor-α, overexpressed in human fat cells

from insulin-resistant subjects. J Biol Chem 2030;278:45777–45784.

Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG. Selenium:

Biochemical roles as a component of glutathione peroxidase. Science 1973; 179: 588-590.

Roxborough HE, Mercer C, McMaster D, Young IS. Plasma glutathione peroxidase activity

is reduced in haemodialysis patients. Nephron 1999;81:278–283.

Ruan H, Miles PD, Ladd CM, Ross K, Golub TR, Olefsky JM, Lodish HF. Profiling gene

transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-

alpha: implications for insulin resistance. Diabetes 2002;51:3176-3188.

Rudich A, Kozlovsky N, Potashnik R, Bashan N. Oxidant stress reduces insulin

responsiveness in 3T3-L1 adipocytes. Am J Physiol 1997;272:E935–40.

Rudich A, Tirosh A, Potashnik R, Hemi R, Kanety H, Bashan N. Prolonged oxidative stress

impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes. Diabetes 1998;47:1562–

1569.

Ruggenenti P, Perna A, Mosconi L, Pisoni R, Remuzzi G. Urinary protein excretion rate is

the best independent predictor of ESRF in non-diabetic proteinuria chronic nephropathies.

“Gruppo Italiano di Studi Epidemiologici in Nefrologia” (GISEN). Kidney Int 1998;53:1209-

1216.

S Saad MJA, Araki E, Miralpeix M, Rothenberg PL, White MF, Kohn CR. Regulation of

insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. J Clin

Invest 1992;90:1839-1849.

Page 39: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

292

Sabater J, Quereda C, Herrera I, Pascual J, Villafruela J, Ortuno J. Nonenzymatic

glycosylation of hemoglobin and total plasmatic proteins in end-stage renal failure. Am J

Nephrol 1991;11:37-43.

Sadaivudu B, Sasikala M, Sailaja V, Reddy SS. Serum malondialdehyde, insulin, glucose and

lipid profile in hypertension. Med Sci Res 1997; 25: 631–633.

Salah N, Miller NJ, Paganga G, Tijburg L, Bolwell GP, Rice-Evans C. Polyphenolic

flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch

Biochem Biophys 1995;322:339-346.

Salmeen A, Andersen JN, Myers MP, Meng TC, Hinks JA, Tonks NK, Barford D. Redox

regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate.

Nature 2003;423:769–773.

Salonen JT, Nyyssonen K, Tuomainen TP, et al. Increased risk of non-insulin dependent

diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men.

Br Med J 1995; 311: 1124–1127.

Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism.

Nature 2001;414:799-806.

Sathiyapriya V, Bobby Z, Vinod Kumar S, Selvaraj N, Parthibane V, Swapnil G. Evidence

for the role of lipid peroxides on glycation of hemoglobin and plasma proteins in non-diabetic

asthma patients. Clin Chim Acta 2006;366:299-303.

Sathiyapriya V, Selvaraj N, Nandeesha H, Bobby Z, Agrawal A, Pavithran P. Enhanced

glycation of hemoglobin and plasma proteins is associated with increased lipid peroxides

levels in non-diabetic hypertensive subjects. Arch Med Res 2007;38:822-826.

Sathiyapriya V, Selvaraj N, Nandeesha H, Bobby Z, Agrawal A, Sridhar MG, Pavithran P,

Rattina Dasse. Increased glycation of hemoglobin and plasma proteins in normotensive, non-

diabetic obese Indian subjects: putative role of lipid peroxides. Clin Chem Lab Med

2007;45:996-999.

Sasaki S, Yokozawa T, Cho EJ, Oowada S, Kim M. Protective role of gamma-aminobutyric

acid against chronic renal failure in rats. J Pharm Pharmacol 2006;58:1515-25.

Scanferla F, Landini S, Fracasso A, Righetto F, Scanferla F, Toffoletto P, Genchi R, Bazzato

G. Risk factors for the progression of diabetic nephropathy: Role of hyperlipidemia and its

correction. Acta Diabetol 1992;29:268-272.

Schmid E, El Benna J, Galter D, Klein G, Dr ge W. Redox priming of the insulin receptor β-

chain associated with altered tyrosine kinase activity and insulin responsiveness in the

absence of tyrosine autophosphorylation. FASEB J. 1998;12:863–870.

Page 40: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

293

Schmitt TL, Hotz-Wagenblatt A, Klein H, Dr ge WJ. Interdependent regulation of insulin

receptor kinase activity by ADP and hydrogen peroxide. J Biol Chem 2005;280:3795–3801.

Schmitz A, Vaeth M. Microalbuminuria: a major risk factor in non-insulin-dependent

diabetes. A 10-year follow up study of 503 patients. Diabet Med 1988;5:126-134.

Scholze A, Rinder C, Beige J, Riezler R, Zidek W, Tepel M. Acetylcysteine reduces plasma

homocysteine concentration and improves pulse pressure and endothelial function in patients

with end-stage renal failure. Circulation 2004;109:369-374.

Schwartz JC. The role of glycohemoglobin and other proteins in diabetes management.

Diabetes Rev 1995;3:269 –87.

Sechi LA, Catena C, Zingaro L, Melis A, De Marchi S. Abnormalities of glucose metabolism

in patients with early renal failure. Diabetes 2002;51:1226-1232.

Senn JJ, Klover PJ, Nowak IA, Mooney RA. Interleukin-6 induces cellular insulin resistance

in hepatocytes. Diabetes 2002;51:3391–3399.

Shah SV. Role of reactive oxygen metabolites in experimental glomerular disease. Kidney

Dis 1989;35:1093-1106.

Shah OJ, Wang Z, Hunter T. Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette

induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Curr Biol

2004;14:1650-1656.

Shahidi F, Wanasundara PD. Phenolic antioxidants. Critical Reviews in Food Science and

Nutrion 1992;32:67-103.

Sharma K, Khosla PK, Tiwari HK, Sharma RK, Bajaj JS. Anti-insulin antibodies and

retinopathy in juvenile onset type-1 diabetes. Indian J Ophthalmol 1991;39:174–5.

Sheehan EW, Zematis MA. A constituent of Pterocarpus Marsupium, (-)-epicatechin, as a

potential antidiabetic agent. J Nat Prod 1983;46:232-234.

Shin MJ, Park E, Lee JH, Chung N. Relationship between insulin resistance and lipid

peroxidation and antioxidant vitamins in hypercholestrolemic patients. Ann Nutr Metab

2006;50:115–120.

Shlipak MG, Fried LF, Crump C, Bleyer AJ, Manolio TA, Tracy RP, Furberg CD, Psaty BM.

Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal

insufficiency. Circulation 2003;107:87–92.

Sies H, Sharov VS, Klotz LO, Briviba K. Glutathione peroxidase protects against

peroxynitrite-mediated oxidations: a new function for selenoproteins as peroxynitrite

reductase, J Biol Chem 1997;272:27812– 27817.

Page 41: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

294

Sinha S, Perdomo G, Brown NF, Doherty RM. Fatty acids induced insulin resistance in L6

myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor

kappa B. J Biol Chem 2004;279:41294-41301.

Sit D, Kardioglu AK, Kayabasi H, Yilmaz ME. The prevalence of insulin resistance in

nondiabetic nonobese patients with chronic kidney disease. Adv Ther 2006;23:988-998.

Slatter AD, Murray M, Bailey AJ. Formation of a dihydropyridine derivative as a potential

cross-link from malondialdehyde in physiological systems. FEBS Lett 1998;421:180-184.

Slatter DA, Bolton CH, Bailey AJ. The importance of lipid-derived malondialdehyde in

diabetes mellitus. Diabetologia 2000;43:550-557.

Smith WGJ, Holden M, Benton M, Brown CB. Carbamylated haemoglobin in chronic renal

failure. Clin Chim Acta 1988;178:297-304.

Stachowska E, Wesolowska T, Olszewska M, Safranow K, Millo B, Domanski L,

Jakubowska K, Ciechanowski K, Chlubek D. Elements of Mediterranean diet improves

oxidative status in blood of kidney graft recipients. Br J Nutr 2005;93:345–352.

Stadtman ER. Metal ion in catalyzed oxidation of proteins: Biochemical mechanism and

biological consequences. Free Radic Biol Med 1990; 9: 315-325.

Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witzum JL. Beyond cholesterol:

modifications of low-density lipoprotein that increases its atherogenicity. N Eng J Med 1989;

320: 915-924.

Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD. Insulin mediated skeletal

muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric

oxide release. J Clin Invest 1994; 94:1172–1179.

Stenvinkel P, Ottosson-Seeberger A, Alvestrand A. Renal hemodynamics and sodium

handling in moderate renal insufficiency: The role of insulin resistance and dyslipidemia. J

Am Soc Nephrol 1994;5:1751-1760.

Stenvinkel P, Heimburger O, Paultre F, Diczfalusy U, Wang T, Berglund L, Jogestrand T.

Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal

failure. Kidney Int 1999;55:1899-1911.

Stenvinkel P, Alvestrand P. Inflammation in end-stage renal disease: Sources, consequences

and therapy. Semin Dial 2002;15:330–338.

Stenvinkel P, Barany P, Heimbürger O, Pecoits-Filho R, Lindholm B. Mortality, malnutrition

malnutrition and atherosclerosis in end-stage renal disease: What is the role of interleukin-6?

Kidney Int 2002; 61:S103–S108.

Page 42: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

295

Stenvinkel P, Ketteler M, Johnson RJ, Lindholm B, Pecoits-Filho R, Riella M, Heimbürger

O, Cederholm T, Girndt M. IL-10, IL-6, and TNF-a: Central factors in the altered cytokine

network of uremia—The good, the bad, and the ugly. Kidney Int 2005;67:1216–1233.

Stolba P, Hatle K, Krnakova A, Streda M, Starka L. Effects of ascorbicacid on nonenzymatic

glycation of serum proteins in vitro and in vivo. Diabetologia 1987;30:585A

Sommerburg O, Grune T, Ehrich JHH, Siems WG. Adaptation of glutathione peroxidase

activity to oxidative tress occurs in children but not in adult patients with end-stage renal

failure undergoing hemodialysis. Clin Nephrol 2002;58:S31–S36.

Sundaram RC, Selvaraj N, Vijayan G, Bobby Z, Hamide A, Rattina Dasse N. Increased

plasma malondialdehyde and fructosamine in iron deficiency anemia: effect of treatment.

Biomed Pharmacother 2007;61:682-685.

Suematsu M, Suzuki H, Delano A, Schmid-Schonbein GW. The inflammatory aspect of the

microcirculation in hypertension; oxidative stress, leukocytes/endothelial interaction,

apoptosis. Microcirculation 2002;9:259-276.

Sugarman BJ, Aggarwal BB, Hass PE, et al. Recombinant human tumor necrosis factor-

alpha: Effects on proliferation of normal and transformed cells in vitro. Science

1985;230:943–945.

Sutherland BA, Rahman RM, Appleton I. Mechanisms of action of green tea catechins, with

a focus on ischemia-induced neurodegeneration. J Nutr Biohcem 2006;17:291-306.

Suyama K, Kabuyama Y, Suzuki S, Kawasaki Y, Suzuki J, Suzuki H, Homma Y. Induction

of transcription factor AP-2 by cytokines and prostaglandins in cultured mesangial cells. Am

J Nephrol 2001;21,307–314.

Svenungsson E, Feig Z, Jensen-Urstad K, de Faire U, Hamsten A, Frostegard J. TNF-alpha:

A link between hypertriglyceridaemia and inflammation in SLE patients with cardiovascular

disease. Lupus 2003;12:454–461.

T

Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, Hirano T, Kishimoto T.

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130.

Cell 1989;58:573–581.

Takahashi T, Kubita M, Nakamura T, Ebihara I, Koide H. Interleukin-6 gene expression in

peripheral mononuclear cells from patients undergoing hemodialysis or continuous

ambulatory peritoneal dialysis. Ren Fail 2000;22:345–354.

Page 43: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

296

Talior I, Tennenbaum T, Kuroki T, Eldar-Finkelman H. Increased risk of obesity resulting

from the interaction between high energy intake and the Trp64Arg polymorphism of the

beta3-adrenergic receptor gene in healthy Japanese men. J Epidemiol 2005;15:203-10.

Tamashiro M, Iseki K, Sunagawa O, Inoue T, Higa S, Afuso H, Fukiyama K.Significant

association between the progression of coronary artery calcification and dyslipidemia in

patients on chronic hemodialysis. Am J Kidney Dis 2001;38:64-9.

Taniguchi T, Koido Y, Aiboshi J, Yamashita T, Suzaki S, Kurokawa A: Change in the ratio

of interleukin-6 to interleukin-10 predicts a poor outcome in patients with systemic

inflammatory response syndrome. Crit Care Med 1999;27:1262–1264.

Tanti JF, Gremeaux T, Obberghen E, Marchand-Brustel Y, Serine/threonine phosphorylation

of insulin receptor substrate 1 modulates insulin receptor signaling. J Biol Chem

1994;269:6051– 6057.

Tas S, Dirican M, Sarandol E, Serdar Z. The effect of taurine supplementation on oxidative

stress in experimental hypothyroidism. Cell Biochem Funct 2006;24:153-158.

Taylor SI, Samuels B, Roth J, et al. Decreased insulin binding in cultured lymphocytes from

two patients with extreme insulin resistance. J Clin Endocrinol Metab 1982;54:919–30.

Tepel M, van der Giet M, Statz M, Jankowski J, Zidek W. The antioxidant acetylcysteine

reduces cardiovascular events in patients with end-stage renal failure: a controlled trial.

Circulation 2003;107:992-995.

Teruel T, Hernandez R, Lorenzo M. Ceramide mediates insulin resistance by tumor necrosis

factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state.

Diabetes 2001;50:2563–2571.

Tesio F, Cecchin E, De Marchi S, Quaia P. Glycosylated or carbamylated hemoglobin in

uremia? N Engl J Med 1982;306:1053.

Testa R, Testa I, Manfrini S, Bonfigli AR, Piantanelli I, Marra M, Pieri C. Glycosylated

hemoglobin and fructosamines: does their determination really reflect the glycemic control in

diabetic patients. Life Sci 1996;59:43-49.

Thornalley PJ. Advanced glycation and the development of diabetic complications. Unifying

the involvement of glucose, methylglyoxal and oxidative stress. Endocrinol Metab

1996;3:149–66.

Timoshanko JR, Sedgwick JD, Holdsworth SR, Tipping PG. Intrinsic renal cells are the

major source of tumor necrosis factor contributing to renal injury in murine crescentic

glomerulonephritis. J Am Soc Nephrol 2003;14:1785–1793.

Page 44: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

297

Tintut Y, Patel J, Parhami F, Demer LL. Tumor necrosis factor α promotes in vitro

calcification of vascular cells via the cAMP pathway. Circulation 2000;102:2636–2642.

Tipping PG, Leong TW, Holdsworth SR. Tumor necrosis factor production by glomerular

macrophages in anti-glomerular basement membrane glomerulonephritis in rabbits. Lab

Invest 1991;65:272–279.

Tirosh A, Potashnik R, Bashan N, Rudich A. Oxidative stress disrupts insulin-induced

cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in

3T3-L1 adipocytes: A putative cellular mechanism for impaired protein kinase B activation

and GLUT4 translocation. J Biol Chem 1999;274:10595–10602.

Tirosh A, Rudich A, Potashnik R, Bashan N. Oxidative stress impairs insulin but not platelet-

derived growth factor signalling in 3T3-L1 adipocytes. Biochem J 2001;355:757–763.

Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide

gels to nitrocellulose sheets. Pro Natl Acad Sci 1975; 16, 4350-4354.

Trachtman H, Futterweit S, Maesaka J, Ma C, Valderrama E, Fuchs A, Tarectecan AA, Rao

PS, Sturman JA, Boles TH,. Taurine ameliorates chronic streptozotocin-induced diabetic

nephropathy in rats. Am J Physiol 1995;269:F429-38.

Trevisan M, Browne R, Ram M, Muti P, Freudenheim J, Carosella M, Armstrong D.

Correlates of markers of oxidative stress in the general population. Am J Epidemiol

2001;154:348-356.

Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Functional in vivo

interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. PNAS 2006;

103: 10741–6.

Turrens JF, Boveris A. Generation of superoxide anions by the NADH dehydrogenase of

bovine heart mitochondria. Biochem J 1980;191:421–427.

U

Um SH, Frogerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini

PR, Kozma SC, Aumerx J, Thomas G. Absence of S6K1 protects against age- and diet-

induced obesity while enhancing insulin sensitivity. Nature 2004;431:200-205.

Uma K, Rondeau E, Jean-Daniel S, Michael AF, Tsilibary EC. Alterations in human

glomerular epithelial cells interacting with non-enzymatically glycosyalted matrix. J Biol

Chem 1997;44:27966– 70.

Page 45: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

298

Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced

insulin resistance in mice lacking TNF-alpha function. Nature 1997;389:610–614.

V

van Dissel JT, van Langevelde P, Westendorp RG, Kwappenberg K, Frolich M. Anti-

inflammatory cytokine profile and mortality in febrile patients. Lancet 1998;351:950–953.

Vareesangthip K, Tong P, Wilkinson R, Thomas TH. Insulin resistance and adult polycystic

kidney disease. Kidney Int 1997;52:503-508.

Vaziri ND, Ni Z, Oveisi F, Liang K, Pandian R. Enhanced nitric oxide inactivation and

protein nitration by reactive oxygen species in renal insufficiency. Hypertension

2002;39:135-141.

Vaziri ND. Dyslipidemia of chronic renal failure: the nature, mechanisms, and potential

consequences. Am J Physiol Renal Physiol. 2006;290:F262-72.

Verma S, Li SH, Badiwala MV, Weisel RD, Fedak PW, Li RK, Dhillon B, Mickle DA.

Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-

reactive protein. Circulation 2002;105:1890–1896.

Venkatesan A, Hemalatha A, Bobby Z, Selvaraj N, Sathiyapriya V. Nonenzymatic glycation

of plasma proteins in smokers. Indian J Physiol Pharmacol 2006;50:403-408.

Venugopal SK, Devaraj S, Yuhanna I, Shaul P, Jialal I.. Demonstration that C-reactive

protein decreases eNOS expression and bioactivity in human aortic endothelial cells.

Circulation 2002;106:1439–1441.

Vijayalingam S, Parthiban A, Shanmugasundaram KR, Mohan V. Abnormal antioxidant

status in impaired glucose tolerance and non-insulin-dependent diabetes mellitus. Diabet Med

1996;13: 715–719.

Vijayan G, Sundaram RC, Bobby Z, Hamide A, Selvaraj N, Rattina Dasse N. Increased

plasma malondialdehyde and fructosamine in anemic H. pylori infected patients: effect of

treatment. World J Gastroenterol 2007;13:796-800.

Vina JR, Saez GT, Vina J. The physiological fuctions of glutathione. In: CRC Hand Book of

Free Radicals and Antioxidants in Biomedicine. Miquel J, Quantaniha AT, Weber H (eds),

CRC Press Inc., Boca Raton, 1989; p 121-132.

Vinson JA, Teufel K, Wu N. Green and black teas inhibit atherosclerosis by lipid,

antioxidant, and fibrinolytic mechanisms. J Agric Food Chem 2004;52:3661-5.

Page 46: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

299

Vinayaga Moorthi R, Bobby Z, Selvaraj N, Sridhar MG. Vitamin E protects the insulin

sensitivity and redox balance in rat L6 muscle cells exposed to oxidative stress. Clin Chim

Acta 2006;367:132–136.

Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, Tatranni PA. High white blood

cell count is associated with a worsening of insulin sensitivity and predicts the development

of type 2 diabetes. Diabetes 2002;51:455–461.

W

Wagner BA, Buettner GR, Burns CP. Free-radical mediated lipid peroxidation in cells:

oxidizability is a function of cell lipid bis-allylic hydrogen content. Biochemistry

1994;33:4449–4453.

Walker WG. Relation of lipid abnormalities to progression of renal damage in essential

hypertension, insulin-dependent and non-insulin-dependent diabetes mellitus. Miner

Electrolyte Metab 1993;19:137-143.

Waltner-Law ME, Wang XL, Law BK, Hall RK, Nawano M, Granner DK. Epigallocatechin

gallate, a constituent of green tea, represses hepatic glucose production. J Biol Chem

2002;277:34933-40.

Wang CC, Goalstone ML, Draznin B. Molecular mechanisms of insulin resistance that

impact cardiovascular biology. Diabetes 2004;53:2735–40.

Wang X, Peesapati SK, Renedo MF, Moktan S. Hemoglobin A1C levels in non-diabetic

patients with end-stage renal disease (ESRD) receiving hemodialysis. J Endocrinol Invest

2004;27:733-735.

Wanner C, Metzger T. C-reactive protein a marker for all-cause and cardiovascular mortality

in haemodialysis patients. Nephrol Dial Transplant 2002;17:29-32.

Weigert C, Hennige AM, Tasja Brischmann T, Moeschel K, Myriam S, Rainer L. The

phosphorylation of Ser318 of insulin receptor substrate- 1 is not per se inhibitory in skeletal

muscle cells but is necessary to trigger the attenuation of the Insulin-stimulated signal. J

Biol Chem 2005;280, 37393–37399.

Wells-Knecht KJ, Brinkmann E, Wells-Knecht MC, Litchfield JE, Ahmed MU, Reddy S,

Zyzak DV, Thorpe SR, Baynes JW. New biomarker of Maillard reaction damage to proteins.

Nephrol Dial Transplant 1996;11:41-47.

Page 47: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

300

Wendel A. Glutathione peroxidase. Methods Enzymol 1981; 77:325–333.

West IC. Radicals and oxidative stress in diabetes. Diabet Med 17:171–180, 2000.

Westervelt FB. Insulin effect in uremia. J Lab Clin Med 1969;74:79-84.

White MF. Insulin signalling in health and disease. Science 2003;302:1710-1711.

Wild S, Sireee R, Roglic G, King H, Green A. Global prevalence of diabetes. Estimates for

the year 2000 and projection for 2030. Diabetes Care 2004;27:1047–1053.

Williams ME, Lacson E Jr, Ofsthun N, Lazarus JM. Hemodialysis type 1 and type II diabetic

patients in the US: characteristics, glycemic control, and survival. Kidney Int 2006;70:1503-

1509.

Wilkinson KD. Signal transduction: aspirin, ubiquitin and cancer. Nature 2003;424:738–739.

Wiseman SA, Balentine DA, Frei B. Antioxidants in tea. Critical Reviews in Food Science

and Nutrition 1997;37:705-718.

Wolf G, Butzmann U, Wenzel UO. The rennin-angiotensin system and progression of renal

disease: from hemodynamics to cell biology. Nephron Physiol 2003;93:P3-P13.

Wolff SP, Dean RT. Glucose autoxidation and protein modification and protein modification:

the potential role of autoxidative glycosylation in diabetes. Biochem J 1988;256: 205– 12.

Wright Jr E, Scism-Bacon JL, Glass LC. Oxidative stress in type 2 diabetes: the role of

fasting and postprandial glycaemia. Int J Clin Pract 2006;60:308–314.

Wu LY, Juan CC, Hwang LS, Hsu YP, Ho PH, Ho LT. Green tea supplementation

ameliorates insulin resistance and increase glucose transport IV content in a fructose-fed rat

model. Eur J Nutr 2004;43:116-124.

Wu CC, Hsu MC, Hsieh CW, Lin JB, Lai PH, Wung BS. Upregulation of heme oxygenase-1

by epigallocatechin-3 gallate via the phosphatidylinositol 3 kinase/Akt and ERK pathways.

Life Sci 2006;78:2889-2897.

X

Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and

JNK-p38 MAP kinases on apoptosis. Science 1995;270, 1326–1331.

Xu L, Badr MZ. Enhanced potential for oxidative stress in hyperinsulinemic rats: imbalance

between hepatic peroxisomal hydrogen peroxide production and decomposition due to

hyperinsulinemia. Horm Metab Res 1999;31:278–282.

Page 48: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

301

Y

Yagi K. Assay for blood plasma or serum lipid peroxides. Methods Enzymol 1984;105:28–

31.

Yamaoka S, Courtois G, Bessia C, Whiteside ST, Weil R, Agou F, Kirk HE, Kay RJ, Israel

A. Complementation cloning of NEMO, a component of the IkappaB kinase complex

essential for NF-kappaB activation. Cell 1998;93:1231–1240.

Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K,

Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML,

Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel

P, Kadowaki T. The fat-derived hormone adiponectin reverses insulin resistance associated

with both lipoatrophy and obesity. Nat Med 2001;7:941–946.

Yeun JY, Kaysen GA. C-reactive protein, oxidative stress, homocysteine, and troponin as

inflammatory and metabolic predictors of atherosclerosis in ESRD. Curr opin Nephrol

Hypertens 2000;9:621-630.

Yeung JH. Effects of glycerol-induced acute renal failure on tissue glutathione and

glutathione-dependent enzymes in the rat. Methods Find Exp Clin Pharmacol 1991;13:23-8.

Yue DK, McLennan S, Church DB, Turtle JR. The measurement of glycosylated hemoglobin

in man and animals by aminophenylboronic acid affinity chromatography. Diabetes

1982;31:701– 5.

Yildirim Z, Kilic N, Ozer C, Babul A, Take G, Erdogan D. Effects of taurine in cellular

responses to oxidative stress in young and middle-aged rat liver. Ann N Y Acad Sci 2007;

1100:553-561.

Yokozawa T, Zheng PD, Oura H, Koizumi F. Animal model of adenine-induced chronic

renal failure in rats. Nephron 1986;44:230-234.

Yokozawa T, Him HW,Kim HY, Tanaka T, Sugino H, Okubo T, Chu D-C, Juneja LJ. Amla

(Emblica officinalis Gaertn.) Attenuates Age-Related Renal Dysfunction by Oxidative Stress.

J Agric Food Chem 2007,55:7744–7752.

Youngren JF, Paik Bernard JR, Impaired insulin receptor autophosphorylation is an early

defect in fat-fed, insulin resistant rats. Am J Physiol 2001;91, 2240-2247.

Page 49: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

302

Yoshimura S, Suemizu H, Nomoto Y, Sakai H, Katsuoka Y, Kawamura N, Moriuchi T.

Plasma glutathione peroxidase deficiency caused by renal dysfunction. Nephron 1996;73:

207–211.

Yoon JW, Pahl MV, Vaziri ND. Spontaneous leukocyte activation and oxygen-free radical

generation in end-stage renal disease. Kidney Int 2007;71:167-172.

Yu BP. Cellular defenses against damage from reactive oxygen species. Physiological

Reviews 1994; 74: 139- 162.

Yuan M, Konstantopoulos N, Lee J, Hansen L, Li ZW, Karin M, Shoelson SE. Reversal of

obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKK- β.

Science 2001;293:1673-1677.

Yudkin JS, Stehouwer CDA, Emeis JJ, Coppack SW. C-reactive protein in healthy subjects:

associations with obesity, insulin resistance, and endothelial dysfunction. Arterioscler

Thromb Vasc Biol 1999;19:972–978.

Yudkin JS, Kumari M, Humphries SE, Mohamed-Ali V. Inflammation, obesity, stress and

coronary heart disease: Is interleukin-6 the link? Atherosclerosis 2000;148:209–214.

Z

Zachara BA, Adamowicz A, Trafikowska U, Pilecki A. Decreased plasma glutathione

peroxidase activity in uremic patients. Nephron 2000;84: 278–279.

Zachara BA, Trafikowska U, Adamowicz A, Nartowicz E, Manitius J. Selenium, glutathione

peroxidases, and some other parameters in blood of patients with chronic renal failure. J

Trace Elem Med Biol 2001;15:161–166.

Zachara BA, Koterska D, Manitius J, Sadowski L, Dziedziczko A, Salak A, Wasowicz W.

Selenium supplementation to patients with the end stage of chronic renal failure has no effect

on the increase of lowered plasma glutathione peroxidase activity. Biol Trace Elem Res

2004a;97: 15–30.

Zachara BA, Salak A, Koterska D, Manitius J, Wasowicz W. Selenium and glutathione

peroxidases in blood of patients with different stages of chronic renal failure. J Trace Elem

Med Biol 2004b;17:291–299.

Zachara BA, Wlodarczyk Z, Andruszkiewicz J, Gromadzinska J, Wasowicz W. Glutathione

and glutathione peroxidase activities in blood of patients in early stages following kidney

transplantation. Ren Fail 2005;27:751-5.

Page 50: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

303

Zanetti M, Barazzoni R, Bosutti A, Stocca A, Grassi G, Guarnieri G. Vascular sources of

oxidative stress: implications for uremia-related cardiovascular disease. J Ren Nutr 2007

17:53-56.

Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. The IkappaB kinase complex

(IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB

phosphorylation and NF-kappaB activation. Cell 1997;91:243–252.

Zaveri NT. Green tea and its polyphenolic catechins: medicinal uses in cancer and noncancer

applications.Life Sci. 2006;78:2073-80.

Zanetti M, Barazzoni R, Bosutti A, Stocca A, Grassi G, Guarnieri G. Vascular sources of

oxidative stress: implications for uremia-related cardiovascular disease. J Ren Nutr

2007;17:53-56.

Zanetti M, Barazzoni R, Guarnieri G. Inflammation and insulin resistance in uremia. J Ren

Nutr 2008;18:70-75.

Zhang B, saku K, Hirata K, Liu R, Tateishi K, Shiomi M, Arakawa K. Quantitative

characterization of insulin-glucose response in Watanabe heritable hyperlipidemic and

cholesterol-Fed rabbits and the effect of cliazapril. Metabolism 1994; 43: 360-366.

Zhou LZ, Johnson AP, Rando TA. NF kappa B and AP-1 mediate transcriptional responses to

oxidative stress in skeletal muscle cells. Free Radic Biol Med 2001;31:1405–1416.

Zhu CH, Huang Y, Oberley LW, Domann FE. A family of AP-2 proteins down-regulate

Manganese superoxide dismutase expression. J Biol Chem 2001;276:14407-14413.

Zimmer S, Pollard V, Marshall GD, Garafalo RP, Traber D, Prough D, Herndon DN. The

1996 Moyer Award. Effects of endotoxin on the Th1/Th2 response in humans. J Burns Care

Rehabil 1996;17:491–496.

Zuckerman SH, O’Neal L. Endotoxin and GM-CSF-mediated down-regulation of

macrophage ApoE secretion is inhibited by a TNF-specific monoclonal antibody. J Leukoc

Biol 1994;55:743–748.

Zwolinska D, Grzeszczak W, Kilis-Pstrucinska K, Szprynger K, Szczepanska M. Lipid

peroxidation and antioxidant enzymes in children with chronic renal failure. Pediatr Nephrol

2004;19:888–892.

Page 51: Chaptershodhganga.inflibnet.ac.in/bitstream/10603/5597/17/17_chapter 9.pdf · Balamurugan R, Bobby Z, Selvaraj N, Nalini P, Koner BC, Sen SK. Increased protein glycation in non-diabetic

304

List of papers publication

1. Selvaraj N, Bobby Z, Sathiyapriya V. Effect of lipid peroxides and antioxidants on

glycation of hemoglobin: An in vitro study on human erythrocytes. Clin Chim Acta 2006;

366: 190-5.

2. Sathiyapriya V, Bobby Z, Vinod Kumar S, Selvaraj N, Parthibane V, Swapnil Gupta.

Evidence for the role of lipid peroxides on glycation of hemoglobin and plasma proteins in

non-diabetic asthma patients. Clin Chim Acta 2006; 366: 299-303. (This paper contains as

part the in vitro study on the effect of H2O2 on glycation of hemoglobin)

3. Selvaraj N, Balamurugan R, Bobby Z, Sathiyapriya V. Increased glycated hemoglobin

level in non-diabetic nephrotic children is associated with oxidative stress. Indian J Physiol

Pharmacol 2007;51:153-159. (This paper contains as part the in vitro study on the effect of

GSH on glycation of hemoglobin)

4. Selvaraj N, Bobby Z, Sridhar MG. Oxidative stress: Does it play a role in the genesis of

early glycated proteins? Medical Hypothesis 2008;70:265-268.

5. Selvaraj N, Bobby Z, Sridhar MG. Increased glycation of hemoglobin in chronic renal

failure: Potential role of oxidative stress. Achieves of Medical Research 2008;39:277-284.

published erratum appears in Archieves of Medical Research 2008;39:466.